type: misc

label: url

en: Varying clinical presentations of nontuberculous mycobacterial disease : Similar to but different from tuberculosis.

en: The incidence rate of pulmonary nontuberculous mycobacterial disease (PNTMD) in Japan is the highest among major industrialized nations. Although the typical clinical course and radiological manifestations of PNTMD are different from those of pulmonary tuberculosis (TB), confusion about these mycobacterial diseases leads to a diagnostic pitfall. Diagnostic challenges include the coexistence of Mycobacterium tuberculosis (MTB) and nontuberculous mycobacteria (NTM), false positives for NTM in MTB nucleic acid amplification tests, microbial substitution, and abnormal radiological manifestations caused by NTM. Features of extrapulmonary NTM diseases, such as pleurisy, vertebral osteomyelitis, and disseminated disease, are different from the corresponding tuberculous diseases. Moreover, the immunological background of the patient (status of human immunodeficiency virus infection with or without antiviral therapy, continuation or discontinuation of immunosuppressive therapy, use of immune checkpoint inhibitor, pregnancy and delivery, etc.) influences the pathophysiology of mycobacterial diseases. This review describes the varying clinical presentations of NTM disease with emphasis on the differences from TB. J. Med. Invest. 68 : 220-227, August, 2021.

en: The Journal of Medical Investigation : JMI


en: 肺非結核性抗酸菌症の診断と治療 : 肺結核との相違点と非典型例を中心に

ja: 肺非結核性抗酸菌症の診断と治療 : 肺結核との相違点と非典型例を中心に

en: Shikoku Acta Medica

ja: 四国医学雑誌


en: 肺がん領域における分子標的薬・免疫チェックポイント阻害薬の現状

ja: 肺がん領域における分子標的薬・免疫チェックポイント阻害薬の現状

en: Journal of Kochi Medical Association

ja: 高知県医師会医学雑誌


en: 慢性咳嗽の鑑別と検査

ja: 慢性咳嗽の鑑別と検査


en: 呼吸器疾患の分子病態と臨床 --- 4)肺癌の分子病態と臨床

ja: 呼吸器疾患の分子病態と臨床 --- 4)肺癌の分子病態と臨床

en: The Journal of the Japanese Society of Internal Medicine

ja: 日本内科学会雑誌