type: misc

label: url

en: 日本人における歯周病のセルフレポートに関する文献レビュー

ja: 日本人における歯周病のセルフレポートに関する文献レビュー

en: Journal of Dental Health

ja: 口腔衛生学会雑誌


en: 樹状細胞を活性化する経鼻アジュバントの開発-感染症・NCD制御を目指す粘膜ワクチン-


en: Periodontal disease, as a lifestyle-related disease, and as a risk factor for several other systemic lifestyle-related diseases

ja: 歯周病予防と生活習慣，そして生活習慣病予防と歯周病

en: The onset and progression of periodontal disease is closely associated with patients' lifestyles and habits, such as smoking, diet, stresses, etc. ; it is therefore considered to be a lifestyle-related disease. It is now listed as one of the complications of diabetes mellitus, as well as disorders of the retina, kidney, nervous system, heart, and brain. In addition to the concept that lifestyles and lifestyle-related diseases are causative factors of periodontal disease, this disease has now been revealed to be involved in the onset and progression of other systemic diseases, such as diabetes, as well as atherosclerosis, which leads to ischemic heart and brain diseases. Proinflammatory cytokines produced in the inflamed gingivae locally and bacteremia induced through the periodontal ulcerative lesions have been suggested to connect the local and systemic disorders. Periodontal diseases can be controlled by adequate risk management and oral health promotion, and this, in turn, contributes to risk reduction for other life-threatening systemic diseases.

en: Shikoku Acta Medica

ja: 四国医学雑誌


en: 歯科治療と感染性心内膜炎の予防

ja: 歯科治療と感染性心内膜炎の予防

en: 四国歯学誌

ja: 四国歯学誌


en: Infective endocarditis and dental procedures: evidence, pathogenesis, and prevention

en: Infective endocarditis is a serious infection occurring on the endothelial surfaces of the heart, especially at the valves. Oral commensal bacteria are the important etiologic agents in this disease. Common dental procedures, even non-surgical dental procedures, can often cause bacteremia of oral commensals. Periodontally diseased patients are at risk from bacteremia even after brushing the teeth. Bacteremia itself rarely affect healthy people but they can result in mortal infective endocarditis in those who have a predisposed risk for this disease, such as those with heart valve diseases, pacemaker implantation, etc. Infective endocarditis is thus established when all the 3 conditions are present simultaneously, i. e., 1) a predisposing impairments in the heart, 2) the introduction of bacteria into the bloodstream, and 3) the virulence of bacteria. Antibiotics have to be adequately used to prevent this infection, however, their frequent uses generates drug-resistant mutant bacteria, which is a serious social problem. The development of novel alternative drugs to be used instead of the current antibiotics is thus highly desired. We are now using several types of combinatorial peptide libraries to search for small size molecular mimetics that can interfere with the adhesion of bacteria to the target organ. The use of such peptides is expected to lead to the development of compounds for a novel preventive drug which does not kill bacteria, thus making it safer and less likely to generate drug-resistant mutants.

en: The Journal of Medical Investigation : JMI


en: 牛乳とむし歯 (う蝕) 予防の関係(2) --- 感染症としてのう蝕に対する受動ワクチン

en: Milk Science

ja: Milk Science


en: 牛乳とむし歯 (う蝕) 予防の関係(1) --- カゼインホスホペプチドのう蝕抑制作用


en: 免疫系の抗原認識と特異性

ja: 免疫系の抗原認識と特異性

en: 鹿児島大学歯学部紀要

ja: 鹿児島大学歯学部紀要


en: 臨床現場でのう蝕予防の実践 --- リスク評価と予防の実際

ja: 臨床現場でのう蝕予防の実践 --- リスク評価と予防の実際

en: 歯科医療

ja: 歯科医療


en: 抗原のポリエチレングリコール修飾によるトレランス誘導

ja: 抗原のポリエチレングリコール修飾によるトレランス誘導

en: Clinical Immunology

ja: 臨床免疫


en: 免疫学からみた歯周病 --- 歯周病患者のT細胞機能

ja: 免疫学からみた歯周病 --- 歯周病患者のT細胞機能

en: The Journal of Dental Medecine

ja: 歯科ジャーナル


en: タバコ使用と口腔微生物の関係 --- 1. 歯の周囲およびインプラント周囲の細菌

en: 日本口腔衛生学会誌

ja: 日本口腔衛生学会誌

misc_type: others


en: 口と全身の疾患と健康を評価する唾液検査法の開発 --- (平成29年度採択プロジェクト研究報告)

en: 日本歯科医学会雑誌

ja: 日本歯科医学会雑誌