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Research Activity

Field of Study

Pathogenic Microbiology, Microbiology, Molecular Biology, Biochemistry

Subject of Study

生理活性物質に対する微生物の応答に関する研究, 病原性微生物の制御に関する研究 (Pseudomonas aeruginosa, multi-drug resistance, antibiotics, quorum sensing, catechin, microcystin)

Book / Paper

Book:

1. 日本微生物生態学会 編集 and Hideaki Maseda :
環境と微生物の辞典,
朝倉書店, Tokyo, Jul. 2014.
2. Hideaki Maseda :
安心・安全・信頼のための抗菌材料,
米田出版, Chiba, Mar. 2010.

Academic Paper (Judged Full Paper):

1. Kazuya Shimizu, Motoo Utsumi, Kunihiro Okano, Tomoaki Itayama, Norio Iwami, Hideaki Maseda, Hiroyuki Kinohira, Norio Sugiura, Jieming Li, Yuhei Inamori, Zhenya Zhang and Norio Sugiura :
Whole-Genome Sequence of the Microcystin-Degrading Bacterium Sphingopyxis sp. Strain C-1.,
Genome Announcements, Vol.3, No.4, 2016.
(DOI: 10.1128/genomeA.00838-15,   PubMed: 26227601,   Elsevier: Scopus)
2. Hidehisa Shimizu, Nanako Baba, Takuma Nose, Ryoko Taguchi, Shinya Tanaka, Ga-Hyun Joe, Hideaki Maseda, Nobuhiko Nomura, Masahito Hagio, Ja-Young Lee, Satoru Fukiya, Atsushi Yokota, Satoshi Ishizuka and Hitoshi Miyazaki :
Activity of ERK regulates mucin 3 expression and is involved in undifferentiated Caco-2 cell death induced by 3-oxo-C12-homoserine lactone.,
Bioscience, Biotechnology, and Biochemistry, Vol.79, No.6, 937-942, 2015.
(DOI: 10.1080/09168451.2015.1006570,   PubMed: 25774422,   Elsevier: Scopus)
3. Akihiro Shirai, Masayoshi Onitsuka, Hideaki Maseda and Takeshi Omasa :
Effect of polyphenols on reactive oxygen species production and cell growth of human dermal fibroblasts after irradiation with ultraviolet-A light,
Biocontrol Science, Vol.20, No.1, 27-33, 2015.
(DOI: 10.4265/bio.20.27,   PubMed: 25817810,   CiNii: 130005061978,   Elsevier: Scopus)
4. Ryoko Taguchi, Shinya Tanaka, Ga-Hyun Joe, Hideaki Maseda, Nobuhiko Nomura, Junji Ohnishi, Satoshi Ishizuka, Hidehisa Shimizu and Hitoshi Miyazaki :
Mucin 3 is involved in intestinal epithelial cell apoptosis via N-(3-oxododecanoyl)-L-homoserine lactone-induced suppression of Akt phosphorylation.,
American Journal of Physiology, Cell Physiology, Vol.307, No.2, C162-8, 2014.
(DOI: 10.1152/ajpcell.00271.2013,   PubMed: 24848113)
5. Masayoshi Onitsuka, Miki Tatsuzawa, Ryutaro Asano, Izumi Kumagai, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
Trehalose suppresses antibody aggregation during the culture of Chinese hamster ovary cells,
Journal of Bioscience and Bioengineering, Vol.117, No.5, 632-638, 2014.
(DOI: 10.1016/j.jbiosc.2013.10.022,   PubMed: 24315529,   CiNii: 110009823142,   Elsevier: Scopus)
6. Ga-Hyun Joe, Midori Andoh, Mikako Nomura, Hitoshi Iwaya, Jae-Sung Lee, Hidehisa Shimizu, Youhei Tsuji, Hideaki Maseda, Hitoshi Miyazaki, Hiroshi Hara and Satoshi Ishizuka :
Acyl-homoserine lactones suppresses IEC-6 cell proliferation and increase permeability of isolated rat colon.,
Bioscience, Biotechnology, and Biochemistry, Vol.78, No.3, 462-465, 2014.
(DOI: 10.1080/09168451.2014.882748,   PubMed: 25036834)
7. Akihiro Shirai, Mutsumi Aihara, Akira Takahashi, Hideaki Maseda and Takeshi Omasa :
Synergistic antimicrobial activity based on the combined use of a gemini-quaternary ammonium compound and ultraviolet A light,
Journal of Photochemistry and Photobiology B: Biology, Vol.130, 226-233, 2014.
(DOI: 10.1016/j.jphotobiol.2013.11.027,   PubMed: 24362318,   Elsevier: Scopus)
8. Akihiro Shirai, Toshiyuki Endo, Hideaki Maseda and Takeshi Omasa :
Synthesis of thiazole derivatives and evaluation of their antiamoebic activity and cytotoxicity,
Biocontrol Science, Vol.18, No.4, 183-191, 2013.
(DOI: 10.4265/bio.18.183,   PubMed: 24366623,   Elsevier: Scopus)
9. Tomohiro Inaba, Yuta Tokumoto, Yusuke Miyazaki, Naoyuki Inoue, Hideaki Maseda, Toshiaki Nakajima-Kambe, Hiroo Uchiyama and Nobuhiko Nomura :
Analysis of genes for succinoyl trehalose lipid production and increasing production in Rhodococcus sp. strain SD-74.,
Applied and Environmental Microbiology, Vol.79, No.22, 7082-7090, 2013.
(DOI: 10.1128/AEM.01664-13,   PubMed: 24038682,   Elsevier: Scopus)
10. Akihiro Shirai, Yasuko Fumoto, Tomoaki Shouno, Hideaki Maseda and Takeshi Omasa :
Synthesis and biological activity of thiazolyl-acetic acid derivatives as possible antimicrobial agents,
Biocontrol Science, Vol.18, No.2, 59-73, 2013.
(DOI: 10.4265/bio.18.59,   CiNii: 130003373489)
11. Hideaki Maseda, Hisaharu Kusaka, Makoto Yamane, Toshiaki Isaka, Kazuhiko Tsutsumi and Shinichi Tebayashi :
Endophytic bacterial diversity in Moso bamboo (Phyllostachys edulis) canes by 16S rDNA sequence analysis,
Journal of Bioindustrial Science, Vol.2, No.1, 8-11, 2013.
12. Uwate Maki, Ichise Yu-ki, Akihiro Shirai, Takeshi Omasa, Nakae Taiji and Hideaki Maseda :
Two routes of MexS-MexT-mediated regulation of MexEF-OprN and MexAB-OprM efflux pump expression in Pseudomonas aeruginosa,
Microbiology and Immunology, Vol.57, No.4, 263-272, 2013.
(DOI: 10.1111/1348-0421.12032,   PubMed: 23586630)
13. Hideaki Maseda, Kazuya Shimizu, Yoshiaki Doi, Yuhei Inamori, Motoo Utsumi, Norio Sugiura and Michihiko Kobayashi :
MlrA Located in the Inner Membrane Is Essential for Initial Degradation of Microcystin in Sphingopyxis sp. C-1,
Journal of Japan Biological Society of Water and Waste, Vol.48, No.3, 99-107, 2012.
(CiNii: 40019441957)
14. Kazuya Shimizu, Hideaki Maseda, Kunihiro Okano, Takumi Kurashima, Yukio Kawauchi, Qiang Xue, Motoo Utsumi, Zhenya Zhang and Norio Sugiura :
Enzymatic pathway for biodegrading microcystin LR in Sphingopyxis sp. C-1.,
Journal of Bioscience and Bioengineering, Vol.114, No.6, 630-634, 2012.
(DOI: 10.1016/j.jbiosc.2012.07.004,   PubMed: 22883536)
15. Akihiro Shirai, Shoko Ueta, Hideaki Maseda, Hiroki Kourai and Takeshi Omasa :
Action of reactive oxygen species in the antifungal mechanism of gemini-pyridinium salts against yeast,
Biocontrol Science, Vol.17, No.2, 77-82, 2012.
(DOI: 10.4265/bio.17.77,   PubMed: 22790843,   CiNii: 10030826450)
16. Uwate Maki, Ichise Yu-ki, Kayama Shizuo, Akihiro Shirai, Miyake Yoichiro, Takeshi Omasa, Nakae Taiji and Hideaki Maseda :
Functionalization of MexT Enhances MexEF-OprN Expression to Overcome Its Repression by MvaT in Pseudomonas aeruginosa,
Journal of Bioindustrial Science, Vol.1, 10-14, 2012.
17. Hideaki Maseda, Doi Yoshiaki, Okano Kunihiro, Sugiura Norio and Kobayashi Michihiko :
Rapid and high efficiency transformation of Sphingomonas and Sphingopyxis by electroporation using frozen cell suspensions,
Journal of Bioindustrial Science, Vol.1, 1-4, 2012.
18. Jieming Li, Kazuya Shimizu, Hideaki Maseda, Zhijiang Lu, Motoo Utsumi, Zhenya Zhang and Norio Sugiura :
Investigations into the biodegradation of microcystin-LR mediated by the biofilm in wintertime from a biological treatment facility in a drinking-water treatment plant,
Bioresource Technology, Vol.106, 27-35, 2012.
(DOI: 10.1016/j.biortech.2011.11.099,   PubMed: 22206920)
19. Shimizu Kazuya, Hideaki Maseda, Okano kunihiro, Itayama Tomoaki, Kawaguchi Yukio, Chen Rongzhi, Utsumi Motoo, Zhang Zhenya and Sugiura Norio :
How microcystin-degrading bacteria express microcystin degradation activity,
Lakes & Reservoirs: Research & Management, Vol.16, 169-178, 2011.
(DOI: 10.1111/j.1440-1770.2011.00480.x)
20. Hideaki Maseda, Hashida Yumiko, Akihiro Shirai, Takeshi Omasa and Nakae Taiji :
Mutation in the sdeS gene promotes expression of the sdeAB efflux pump gene and multidrug resistance in Serratia marcescens,
Antimicrobial Agents and Chemotherapy, Vol.55, No.6, 2922-2926, 2011.
(DOI: 10.1128/AAC.01755-10,   PubMed: 21422216)
21. Akihiro Shirai, 久保山 泰典, 室巻 良彦, Hideaki Maseda and Hiroki Kourai :
The Quantitative Assay of Trophozoites and Cysts of Acanthamoeba by Applying ATP Measurement and the Establishment of an Amoebicidal Test Method,
Journal of Antibacterial and Antifungal Agents, Japan, Vol.38, No.10, 651-660, 2010.
(CiNii: 10026732709)
22. Hideaki Maseda, Maki Uwate and Taiji Nakae :
Transcriptional regulation of the mexEF-oprN multidrug efflux pump operon by MexT and an unidentified repressor in nfxC-type mutant of Pseudomonas aeruginosa,
FEMS Microbiology Letters, Vol.311, No.1, 36-43, 2010.
(DOI: 10.1111/j.1574-6968.2010.02063.x,   PubMed: 20727012)
23. Akihiro Shirai, 森下 裕生, Hideaki Maseda and Hiroki Kourai :
The Development of Gemini-Quaternary Ammonium Compound-Supported Inorganic-Organic Hybrids as Antimicrobial Materials,
Journal of Antibacterial and Antifungal Agents, Japan, Vol.38, No.3, 133-142, 2010.
(CiNii: 10026327124)
24. Yasuo Jimbo, Kunihiro Okano, Kazuya Shimizu, Hideaki Maseda, Motoo Utsumi and Norio Sugiura :
Quantification of Microcystin-degrading Bacteria in a Biofilm from a Practical Biological Treatment Facility by Real-time PCR,
Journal of Water and Environment Technology, Vol.8, No.3, 193-201, 2010.
(DOI: 10.2965/jwet.2010.193)
25. Kunihiro Okano, Kazuya Shimizu, Yukio Kawauchi, Hideaki Maseda, Motoo Utsumi, Zhenya Zhang, Brett A Neilan and Sugiura Norio :
Characteristics of a Microcystin-Degrading Bacterium under Alkaline Environmental Conditions.,
Journal of Toxicology, Vol.2009, 1-8, 2009.
(DOI: 10.1155/2009/954291,   PubMed: 20224628)
26. Hideaki Maseda, Hashida Yumiko, Konaka Rumi, Akihiro Shirai and Hiroki Kourai :
Mutational upregulation of a resistance-nodulation-cell division-type multidrug efflux pump, SdeAB, upon exposure to a biocide, cetylpyridinium chloride, and antibiotic resistance in Serratia marcescens,
Antimicrobial Agents and Chemotherapy, Vol.53, No.12, 5230-5235, 2009.
(DOI: 10.1128/AAC.00631-09,   PubMed: 19752278)
27. Yutaka Yawata, Hideaki Maseda, Satoshi Okabe, Akinobu Ito, Isao Sawada, Hiroaki Kurashima, Hiroo Uchiyama and Nobuhiko Nomura :
The Response of Pseudomonas aeruginosa PAO1 Efflux Pump-Defective Mutants to N-Octanoyl-L-Homoserine Lactone,
Microbes and Environments, Vol.24, No.4, 338-342, 2009.
(DOI: 10.1264/jsme2.ME09130,   PubMed: 21566394)
28. Shimizu Kazuya, Okano Kunihiro, Hideaki Maseda, Kurasima Taku, Utsumi Motoo and Sugiura Norio :
Effect of Microcystin and Its Degradation Products on the Transcription of Genes Encoding Microcystion Degrading Enzymes,
Japanese Journal of Water Teatment Biology, Vol.45, No.1, 45-55, 2009.
29. Akihiro Shirai, Tomoko Sumitomo, Mayuko Kurimoto, Hideaki Maseda and Hiroki Kourai :
The mode of the antifungal activity of gemini-pyridinium salt against yeast,
Biocontrol Science, Vol.14, No.1, 13-20, 2009.
(DOI: 10.4265/bio.14.13,   PubMed: 19344094)
30. Sugimura Makoto, Hideaki Maseda, Hanaki Hideaki and Nakae Taiji :
Macrolide Antibiotic-Mediated Downregulation of MexAB-OprM Efflux Pump Expression in Pseudomonas aeruginosa,
Antimicrobial Agents and Chemotherapy, Vol.52, No.11, 4141-4144, 2008.
(DOI: 10.1128/AAC.00511-08,   PubMed: 18676884)
31. Akihiro Shirai, Tomoko Sumitomo, 岡村 菜穂, 大久保 彰洋, 湯浅 明彦, Hideaki Maseda and Hiroki Kourai :
銀担持アクリル繊維を含む抗菌紙の魚病原因細菌に対する殺菌特性,
Journal of Antibacterial and Antifungal Agents, Japan, Vol.36, No.9, 579-585, 2008.
(CiNii: 10024288308)
32. Toyofuku Masanori, Nomura Nobuhiko, Fujii Tatsuya, Takaya Naoki, Hideaki Maseda, Sawada Isao, Nakajima Toshiaki and Uchiyama Hiroo :
Quorum Sensing Regulates Denitrification in Pseudomonas aeruginosa PAO1,
Journal of Bacteriology, Vol.189, No.13, 4969-4972, 2007.
(DOI: 10.1128/JB.00289-07,   PubMed: 17449629)
33. Okano Kunihiro, Hideaki Maseda, Sugita Kazutoshi, Saito Takeshi, Utsumi Motoo, Maekawa Takaaki and Kobayashi Michihikko :
Biochemical characteristics of microcystin LR degradation by typical protease,
Japanese Journal of Water Teatment Biology, Vol.42, No.1, 27-35, 2006.
(CiNii: 10017980631)
34. Shima Eda, Hideaki Maseda, Yoshihara Eisaku and Nakae Taiji :
Assignment of the outer-membrane-subunit-selective domain of the membrane fusion protein in the tripartite xenobiotic efflux pump of Pseudomonas aeruginosa,
FEMS Microbiology Letters, Vol.254, No.1, 101-107, 2006.
(DOI: 10.1111/j.1574-6968.2005.00010.x,   PubMed: 16451186,   Elsevier: Scopus)
35. Hiroshi Fukatsu, Sachio Herai, Yoshireru Hashimoto, Hideaki Maseda, Hiroshi Higashibata and Kobayashi Michihiko :
High-level expression of a novel amine-synthesizing enzyme, N-substituted formamide deformylase, in Streptomyces with a strong protein expression system,
Protein Expression and Purification, Vol.40, No.1, 212-219, 2005.
(DOI: 10.1016/j.pep.2004.11.013,   PubMed: 15721791)
36. Hideo Kobayashi, Asaomi Kuwae, Hideaki Maseda, Akira Nakamura and Takayuki Hoshino :
Isolation of a low-molecular-weight, multicopy plasmid, pNHK101, from Thermus sp. TK10 and its use as an expression vector for T. thermophilus HB27,
Plasmid, Vol.54, No.1, 70-79, 2005.
(DOI: 10.1016/j.plasmid.2004.12.004,   PubMed: 15907540)
37. Sachio Herai, Yoshiteru Hashimoto, Hiroki Higashibata, Hideaki Maseda, Haruo Ikeda, Satoru Omura and Michihiko Kobayashi :
Hyperinducible expression system for streptomycetes,
Proceedings of the National Academy of Sciences of the United States of America, Vol.101, No.39, 14031-14035, 2004.
(DOI: 10.1073/pnas.0406058101,   PubMed: 15377796)
38. Hideaki Maseda, Isao Sawada, Taiji Nakae, Hiroo Uchiyama and Nobuhiko Nomura :
A quorum-sensing autoinducer enhances the mexAB-oprM efflux-pump expression without the MexR-mediated regulation in Pseudomonas aeruginosa.,
Microbiology and Immunology, Vol.48, No.5, 435-439, 2004.
(PubMed: 15215631)
39. Hideaki Maseda, Sawada Isao, Saito Kohjiro, Uchiyama Hiroo, Nakae Taiji and Nomura Nobuhiko :
Enhancement of the mexAB-oprM efflux-pump expression by a quorum-sensing autoinducer and its cancellation by a regulator, MexT, of the mexEF-oprN efflux-pump operon in Pseudomonas aeruginosa,
Antimicrobial Agents and Chemotherapy, Vol.48, No.4, 1320-1328, 2004.
(DOI: 10.1128/AAC.48.4.1320-1328.2004,   PubMed: 15047536,   CiNii: 30020632079)
40. Goh Takayama, Takehide Kosuge, Hideaki Maseda, Akira Nakamura and Takayuki Hoshino :
Nucleotide sequence of the cryptic plasmid pTT8 from Thermus thermophilus HB8 and isolation and characterization of its high-copy-number mutant,
Plasmid, Vol.51, No.3, 227-237, 2004.
(DOI: 10.1016/j.plasmid.2004.01.003,   PubMed: 15109829)
41. Matsuzaka Emiko, Nomura Nobuhiko, Hideaki Maseda, Otagaki Hiroshi, Nakajima-Kambe Toshiaki, Nakahara Tadaatsu and Uchiyama Hiroo :
Participation of nitrite reductase in conversion NO2- to NO3- in a heterotrophic nitrifier, Burkholderia cepacia NH-17, with denitrification activity,
Microbes and Environments, Vol.18, No.4, 203-209, 2003.
(DOI: 10.1264/jsme2.18.203,   CiNii: 110001269348)
42. Eda Shima, Hideaki Maseda and Nakae Taiji :
An elegant means of self-protection in gram-negative bacteria by recognizing and extruding xenobiotics from the periplasmic space,
The Journal of Biological Chemistry, Vol.278, No.4, 2085-2088, 2003.
(DOI: 10.1074/jbc.C200661200,   PubMed: 12460990)
43. Hideaki Maseda, Kitao Masataka, Eda Shima, Yoshihara Eisaku and Nakae Taiji :
A novel assembly process of the multi-component xenobiotic-efflux pump in Pseudomonas aeruginosa,
Molecular Microbiology, Vol.46, No.3, 677-686, 2002.
(DOI: 10.1046/j.1365-2958.2002.03197.x,   PubMed: 12410825)
44. Eisaku Yoshihara, Hideaki Maseda and Kohjiro Saito :
The outer membrane component of the multidrug efflux pump from Pseudomonas aeruginosa may be a gated channel.,
European Journal of Biochemistry, Vol.269, No.19, 4738-4745, 2002.
(DOI: 10.1046/j.1432-1033.2002.03134.x,   PubMed: 12354104)
45. Hiroshi Yoneyama, Hideaki Maseda, Taka-aki Ta Yamabayashi, Shotaro Izumi and Taiji Nakae :
Secondary-site mutation restores the transport defect caused by the transmembrane domain mutation of the xenobiotic transporter MexB in Pseudomonas aeruginosa.,
Biochemical and Biophysical Research Communications, Vol.292, No.2, 513-518, 2002.
(DOI: 10.1006/bbrc.2002.6659,   PubMed: 11906191)
46. Kohjiro Saito, Shima Eda, Hideaki Maseda and Taiji Nakae :
Molecular mechanism of MexR-mediated regulation of MexAB-OprM efflux pump expression in Pseudomonas aeruginosa.,
FEMS Microbiology Letters, Vol.195, No.1, 23-28, 2001.
(PubMed: 11166990)
47. Hideaki Maseda, Kohjiro Saito, Akira Nakajima and Taiji Nakae :
Variation of the mexT gene, a regulator of the MexEF-oprN efflux pump expression in wild-type strains of Pseudomonas aeruginosa.,
FEMS Microbiology Letters, Vol.192, No.1, 107-112, 2000.
(PubMed: 11040437)
48. Hideaki Maseda, Hiroshi Yoneyama and Taiji Nakae :
Assignment of the substrate-selective subunits of the MexEF-OprN multidrug efflux pump of Pseudomonas aeruginosa.,
Antimicrobial Agents and Chemotherapy, Vol.44, No.3, 658-664, 2000.
(DOI: 10.1128/AAC.44.3.658-664.2000,   PubMed: 10681335,   Elsevier: Scopus)
49. Hiroshi Yoneyama, Hideaki Maseda, Hiroshi Kamiguchi and Taiji Nakae :
Function of the membrane fusion protein, MexA, of the MexA, B-OprM efflux pump in Pseudomonas aeruginosa without an anchoring membrane.,
The Journal of Biological Chemistry, Vol.275, No.7, 4628-4634, 2000.
(PubMed: 10671490)
50. Hideaki Maseda and Takayuki Hoshino :
Development of Expression Vectors for Thermus thermophilus,
Journal of Fermentation and Bioengneering, Vol.86, No.1, 121-124, 1998.
51. Hideaki Maseda and Takayuki Hoshino :
Fusion with Ribosomal Protein L32 Incresed the in vivo Thermostability of Kanamycin Nucleotidyltransferase in Thermus thermophilus,
Journal of Fermentation and Bioengneering, Vol.82, No.6, 525-530, 1996.
52. Hideaki Maseda and Takayuki Hoshino :
Screening and analysis of DNA fragments that show promoter activities in Thermus thermophilus.,
FEMS Microbiology Letters, Vol.128, No.2, 127-134, 1995.
(PubMed: 7750730)
53. Takayuki Hoshino, Hideaki Maseda and Tadaatsu Nakahara :
Plasmid Marker Rescue Transformation in Thermus thermophilus. Journal of Fermentation and Bioengneering,
Journal of Fermentation and Bioengneering, Vol.76, 276-279, 1993.

Academic Paper (Unrefereed Paper):

1. Akihiro Shirai, Kyohei Matsumura, Masato Kajiura, Hideaki Maseda and Takeshi Omasa :
フォトクロミック分子を応用した光応答型殺菌剤の開発,
LED総合フォーラム2014-2015 in 徳島 論文集, Vol.P-8, 121-122, 2015.
2. Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
ジェミニ型抗菌剤ハイジェニアとLED近紫外光の併用による相乗殺菌効果とその殺菌機構の解明,
LED総合フォーラム2013 in 徳島 論文集, Vol.P-8, 73-74, 2013.
3. Kobayashi Hiroaki, Shimizu Kazuya, Zhenya Zhang, Sugiura Norio, Takeshi Omasa and Hideaki Maseda :
Characterization of MlrB Involved in Degradation of the Cyanobacterial Toxin Microcystin LR,
Resouces Envionment Life, 186-190, 2011.
4. Uwate Maki, Nakae Taiji, Akihiro Shirai, Takeshi Omasa and Hideaki Maseda :
MexT-mediated Regulation of MexEF-OprN Multidrug Efflux Pump via Nod Box in Pseudomonas aeruginosa,
Resouces Envionment Life, 191-198, 2011.
5. 上手 麻希 and Hideaki Maseda :
緑膿菌多剤排出ポンプMexEF-OprN領域の解析,
緑膿菌感染症研究会, 108-112, 2009.
6. Hideaki Maseda :
A xenobiotic extrusion transporter and a quorum-sensing system,
緑膿菌感染症研究会, 27-32, 2009.
7. Minoru Watanabe, Tadashi Yamashiro, Takanori Satoh, Makoto Ohashi, Hideaki Maseda, Shyouzo Tsuzuki and Takao Hanabusa :
University and High school cooperation project-A report from experience-based study program of high school students in the laboratory of the university-,
Journal of University Education Research, No.6, 85-101, 2009.
(Tokushima University Institutional Repository: 82694,   CiNii: 110007591279)
8. Hideaki Maseda :
An RND-type Multi-drug Efflux Pump and Inhibition of Quorum-sensing System,
Bacterial Adherence & Biofilm, Vol.22, 31-37, 2008.

Review, Commentary:

1. Hideaki Maseda :
Quorum-sensing機構,
呼吸器科, Vol.12, 77-88, Jul. 2007.

Proceeding of International Conference:

1. Akihiro Shirai, Matsumura Kyohei, Masayoshi Onitsuka, Hideaki Maseda and Takeshi Omasa :
Application of photochromism to the molecular design of antimicrobial agents: synthesis of phenolic derivatives and their bactericidal activity based on a photo-reaction with ultraviolet-A light,
III International Conference on Antimicrobial Research, No.T64, 289, Madrid, Oct. 2014.
2. Ichise Yu-ki, Uwate Maki, Akihiro Shirai, Nakae Taiji and Hideaki Maseda :
Role of MexEF-OprN efflux pump in wild type strain of Pseudomonas aeruginosa,
114th General Meeting, American Society for Microbiology, 145, Boston, May 2014.
3. Uwate Maki, Ichise Yu-ki, Nakae Taiji, Akihiro Shirai and Hideaki Maseda :
The mechanism of mexT gene activation in the expression of the mexEF-oprN operon in Pseudomonas aeruginosa,
114th General Meeting, American Society for Microbiology, 168, Boston, May 2014.
4. Ichise Yu-ki, Uwate Maki, Nakae Taiji and Hideaki Maseda :
Analysis of transient expression of MexEF-OprN efflux pump in Pseudomnas aeruginosa,
The 12th Japan-Koria International Symposium on Microbiology 2014, 90, Tokyo, Mar. 2014.
5. Uwate Maki, Ichise Yu-ki, Nakae Taiji and Hideaki Maseda :
Expression of antibiotic resistance genes by specific nucleotide deletion in Pseudomonas aeruginosa,
The 12th Japan-Koria International Symposium on Microbiology 2014, 88, Tokyo, Mar. 2014.
6. Tomomi Tsutsui, Akitoshi Nishizawa, Akihiro Shirai, Masayoshi Onitsuka, Hideaki Maseda and Takeshi Omasa :
Expression profiling in UPR-regulated Chinese hamster ovary cell line,
25th Annual and international meeting of Japanese Association for Animal Cell Technology (JAACT 2012), 107, Nagoya, Nov. 2012.
7. Miki Tatsuzawa, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
Trehalose suppress the antibody aggregation in CHO cell culture,
25th Annual and international meeting of Japanese Association for Animal Cell Technology (JAACT 2012), 106, Nagoya, Nov. 2012.
8. Michiko Hoashi, Mai Takahashi, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
Construction of new mammalian expression vector on the basis of gene-amplified structure in CHO genome,
The 18th Young Asian Biochemical Engineers' Community (YABEC), 118, Tokushima, Oct. 2012.
9. Tomomi Tsutsui, Akitoshi Nishizawa, Akihiro Shirai, Masayoshi Onitsuka, Hideaki Maseda and Takeshi Omasa :
Expression profiling in UPR-engineered Chinese hamster ovary cell line,
The 18th Young Asian Biochemical Engineers' Community (YABEC), 116, Tokushima, Oct. 2012.
10. Miki Tatsuzawa, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
Aggregation-controlled Chinese hamster ovary cell cultivation in antibody production,
The 18th Young Asian Biochemical Engineers' Community (YABEC), 115, Tokushima, Oct. 2012.
11. Akihiro Shirai, Koichiro Sato, Masayoshi Onitsuka, Hideaki Maseda and Takeshi Omasa :
The effect of WFS1 over-expression on recombinant protein production in Chinese Hamster Ovary Cells,
The 18th Young Asian Biochemical Engineers' Community (YABEC), 113, Tokushima, Oct. 2012.
12. Ichise Yu-ki, Uwate Maki, Akihiro Shirai, Takeshi Omasa, Nakae Taiji and Hideaki Maseda :
Regulation of mexT-Mediated mexEF-oprN Expression and mexAB-oprM Depression by An Upper Regulator mexS in Pseudomonas aeruginosa,
The 5th Japan-China-Korea Graduate Student Forum, 110, Tsukuba, Sep. 2012.
13. Uwate Maki, Ichise Yuki, Akihiro Shirai, Takeshi Omasa, Nakae Taiji and Hideaki Maseda :
Regulation of mexT-Mediated mexEF-oprN Expression and mexAB-oprM Depression by an Upper Regulator mexS in Pseudomonas aeruginosa,
American Society for Microbiology 112th General Meeting, 143, San Francisco, Jun. 2012.
14. Masayoshi Onitsuka, Miki Tatsuzawa, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
Suppression of antibody aggregation in CHO cell culture by trehalose addition,
Cell Culture Engineering XIII, 210, Scottsdale, Arizona, USA, Apr. 2012.
15. Tomomi Tsutsui, Akitoshi Nishizawa, Akihiro Shirai, Masayoshi Onitsuka, Hideaki Maseda and Takeshi Omasa :
Gene expression profiles in ATF4-overexpressing CHO cell line,
Cell Culture Engineering XIII, 275, Scottsdale, Arizona, USA, Apr. 2012.
16. Masayoshi Onitsuka, Tatsuzawa Miki, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
Effects of trehalose on antibody production: Supression of protein aggregation and enhancement of productivity,
The 17th Young Asian Biochemical Engineers' Community (YABEC), No.F-9, 121, Incheon, Oct. 2011.
17. Akihiro Shirai, kuboyama Yasunori, Masayoshi Onitsuka, Katsu Satoshi, Takami Takayuki, Hideaki Maseda and Takeshi Omasa :
The effects of CHOP over-expression/down-regulation on recombinant Antithrombin III production in Chinese Hamster Ovary Cells,
The 17th Young Asian Biochemical Engineers' Community (YABEC), No.F-8, 120, Incheon, Oct. 2011.
18. Shimizu Kazuya, Hideaki Maseda, Okano Kunihiro, Itayama Tomoaki, Utsumi Motto, Zhang Zhenya and Sugiura Norio :
Expression of Microcystin degradation activity in microcystin-degrading bacterium,
International Union of Microbiology Societies 2011 Congress, 204, Sapporo, Sep. 2011.
19. Uwae Maki, Ichise Yuki, Akihiro Shirai, Takeshi Omasa, Nakae Taiji and Hideaki Maseda :
MexS cancels the MexT-dependent repression of MexAB-OprM efflux pump in Pseudomonas aeruginosa,
International Union of Microbiology Societies 2011 Congress, 221, Sapporo, Sep. 2011.
20. Akihiro Shirai, Yasuko Fumoto, Hideaki Maseda and Hiroki Kourai :
Synthesis and biological properties of novel anionic surfactant, potassium acetate salt of (5-alkyl-2-methyl-1,3-thiazole)s,
The 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010), No.04-ORGN-1613, 139, Honolulu, Dec. 2010.
21. Toshiyuki Endoh, Kanae Sakaguchi, Hideaki Maseda, Hiroki Kourai, Akihiro Shirai and Takeshi Omasa :
Development of new antimicrobial agents: synthesis and biological properties of hybrid-type quaternary ammonium salts as a safe antimicrobial agent,
The 16th Young Asian Biochemical Engineers' Community (YABEC), No.F-13, 72, Taoyuan, Nov. 2010.
22. Akihiro Shirai, Yuki Ohtsu, Yasunori Kuboyama, Hideaki Maseda, Hiroki Kourai and Takeshi Omasa :
Water disinfection system based on the combined use of gemini-quaternary ammonium salt and ultraviolet (A)-light emitting diode,
The 16th Young Asian Biochemical Engineers' Community (YABEC), No.F-17, 74, Taoyuan, Nov. 2010.
23. Yasuo Jimbo, Kunihiro Okano, Kazuya Shimizu, Hideaki Maseda, Motoo Utsumi and Norio Sugiura :
Quantification and Seasonal Change of Microsystin-Degrading Bacteria by Real-Time PCR,
Journal of Water and Environment Technology, Vol.8, No.3, 193-201, Ishinomaki, Jan. 2010.
(DOI: 10.2965/jwet.2010.193)
24. Hideaki Maseda :
Determination of Membrane Topology of the Microcystin-degrading Enzyme, MlrA, and Construction of its High-level Expressing Cells,
Chiang Mai, Dec. 2009.
25. Akihiro Shirai, Yasuko Fumoto, Shou Nashino, Hideaki Maseda and Hiroki Kourai :
Synthesis and antimicrobial properties of novel anionic heterocyclic surfactant derivatives of 5-alkyl-2-methyl-1,3-thiazole,
42nd IUPAC Congress: Chemistry Solutions, Vol.P206_018, Glasgow, Aug. 2009.
26. Shimizu Kazuya, Okano Kunihiro, Amemiya Takao, Hideaki Maseda, Utsumi Motoo and Sugiura Norio :
Effect of Cyclic Microcystin and Its Degradation Products on Transcription of the Gene Encoding Microcystin Degrading Enzymes,
1st Japan-China Graduated Forum, Tsukuba, Oct. 2008.
27. Shimizu Kazuya, Okano Kunihiro, Hideaki Maseda, Amemiya Takao, Utsumi Motoo and Sugiura Norio :
Effect of Cyclic Microcystin and Its Degradation Products on Transcription of the Gene Encoding Microcystin Degrading Enzymes,
12th International Symposium on Microbiol Ecology, Cairns, Aug. 2008.
28. Takuya Maeda, Ryoko Buma, Masaharu Kamei, Hideaki Maseda and Hiroki Kourai :
Pathogenic Bacteria Carried by Houseflies and The Possibility of Transmission from Source to Human,
Second Bangladesh-Japan Joint International Conference of Microbiology and Food Hygiene, 31-34, Nara, Dec. 2006.

Proceeding of Domestic Conference:

1. Hideaki Maseda :
多剤耐性菌に立ち向かう,
Nippon Kagaku Kaishi,
2. Hideaki Maseda :
Multidrug efflux pump contributes to antibiotic resistance in persisters of Pseudomonas aeruginosa,
日本細菌学会雑誌, Vol.71, No.1, 42, Mar. 2016.
3. 上手 麻希, 市瀨 裕樹, 北島 圭, Akihiro Shirai, 中江 太治 and Hideaki Maseda :
Novel gene regulation system mediated by rearrangement,
日本細菌学会雑誌, Vol.71, No.1, 144, Mar. 2016.
4. 市瀨 裕樹, 上手 麻希, 北島 圭, Akihiro Shirai, 中江 太治 and Hideaki Maseda :
Analysis of the transient resistant cells in Pseudomonas aeruginosa,
日本細菌学会雑誌, Vol.71, No.1, 143, Mar. 2016.
5. Hideaki Maseda :
Antibiotic resistance obtained at the expense in Pseudomonas aeruginosa,
日本細菌学会雑誌, Vol.71, No.1, 20, Mar. 2016.
6. Hideaki Maseda :
緑膿菌の遺伝子制御系を読み解く,
第49回緑膿菌感染症研究会プログラム, Vol.1, No.1, 1, Mar. 2016.
7. Keiji Murakami, Hideaki Maseda, 天羽 崇, Katsuhiko Hirota, Keiko Kataoka and Yoichiro Miyake :
臨床および環境分離緑膿菌の抗菌薬抵抗性と病原因子に関する検討,
第88回日本細菌学会総会, Mar. 2015.
8. Hideaki Maseda :
DNAレベルでのスプライシングによる隠れ遺伝子発現機構,
近畿バイオインダストリー振興会議, Feb. 2015.
9. 北島 圭, 上手 麻希, 市瀬 裕樹, Akihiro Shirai, 中江 太治 and Hideaki Maseda :
多剤耐性緑膿菌NfxC変異株におけるOprDポーリンの発現機構の解析,
Nihon Saikingaku Zasshi, Vol.70, No.1, 194, Feb. 2015.
10. 市瀬 裕樹, 上手 麻希, 北島 圭, Akihiro Shirai, 中江 太治 and Hideaki Maseda :
緑膿菌MexEF-OprN薬剤排出ポンプの新規発現機構の解析,
Nihon Saikingaku Zasshi, Vol.70, No.1, 192, Feb. 2015.
11. 上手 麻希, 市瀬 裕樹, 北島 圭, 中江 太治 and Hideaki Maseda :
特異的欠失によるゲノムへの薬剤耐性調節遺伝子mexTの出現,
Nihon Saikingaku Zasshi, Vol.70, No.1, 192, Feb. 2015.
12. Shoko Kannuki, Yukari Yoshikawa, Keiji Murakami, Yoichiro Miyake, Hideaki Maseda, 畑 美智子, 佐藤 雅美, 笹田 倫子, 香川 葉子, 菅崎 幹樹, Momoyo Azuma, Akiko Sakurai and Keiko Kataoka :
臨床および環境分離緑膿菌における病原性について,
第38回徳島県医学検査学会, Dec. 2014.
13. Akihiro Shirai, Kyohei Matsumura, Masayoshi Onitsuka, Hideaki Maseda and Takeshi Omasa :
新規抗菌剤の分子設計におけるフォトクロミック特性の応用,
日本防菌防黴学会第41回年次大会要旨集, No.24Ap-12, 55, Sep. 2014.
14. Yuki Ichise, Uwate Maki, Takeshi Omasa and Hideaki Maseda :
緑膿菌MexEF-OprN薬剤排出ポンプの一過的な発現調節機構,
2014年度日本農芸化学会大会講演要旨集, 444, Mar. 2014.
15. Uwate Maki, Yuko Yokota, Takeshi Omasa and Hideaki Maseda :
緑膿菌ゲノムでの薬剤耐性調節遺伝子mexTの出現,
2014年度日本農芸化学会大会講演要旨集, 443, Mar. 2014.
16. Uwate Maki, Yuko Yokota, Kuroyama Ami, Ichise Yu-ki, Akihiro Shirai, Nakae Taiji and Hideaki Maseda :
多剤耐性緑膿菌NfxC変異株におけるイミペネム耐性機構の解析,
日本細菌学会雑誌, Vol.69, No.1, 201, Mar. 2014.
17. Ichise Yu-ki, Uwate Maki, Kuroyama Ami, Yuko Yokota, Akihiro Shirai, Nakae Taiji and Hideaki Maseda :
MexEF-OprN薬剤排出ポンプの発現と緑膿菌野生株での役割,
日本細菌学会雑誌, Vol.69, No.1, 200, Mar. 2014.
18. Kuroyama Ami, Ichise Yu-ki, Uwate Maki, Yuko Yokota, Akihiro Shirai, Nakae Taiji and Hideaki Maseda :
多剤耐性緑膿菌NfxC変異株におけるイミペネム耐性機構の解析,
日本細菌学会雑誌, Vol.69, No.1, 200, Mar. 2014.
19. Yuko Yokota, Uwate Maki, Ichise Yu-ki, Kuroyama Ami, Akihiro Shirai, Nakae Taiji and Hideaki Maseda :
特定の塩基配列の欠失による耐性関連遺伝子出現機構の解析,
日本細菌学会雑誌, Vol.69, No.1, 200, Mar. 2014.
20. Hideaki Maseda, 上手 麻希, Keiji Murakami and Yoichiro Miyake :
環境および臨床由来緑膿菌の特性比較,
第61回日本化学療法学会西日本支部総会, Nov. 2013.
21. Airi Honjoh, Miyuki Edagawa, Kazuaki Mawatari, Miki Maetani, Mutsumi Aihara, Takaaki Shimohata, Takashi Uebansou, Maki Uwate, Hideaki Maseda and Akira Takahashi :
トランスポゾン挿入変異ライブラリを用いた腸炎ビブリオの近紫外線関連遺伝子の探索,
第66回 日本細菌学会中国・四国支部総会, Oct. 2013.
22. 野田 真広, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
二重特異性抗体のドメイン配置が凝集性に及ぼす影響,
第65回日本生物工学会大会, 245, Sep. 2013.
23. 森下 明彦, 高橋 舞, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
異数性を有するChinese hamster ovary細胞における染色体不安定性解析,
第65回日本生物工学大会, 245, Sep. 2013.
24. 高橋 舞, 森下 明彦, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
Chinese hamster ovary 細胞株における染色体不安定性解析と抗体生産への応用,
第65回日本生物工学大会, 73, Sep. 2013.
25. 筒井 智美, Kyoung Ho Lee, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
細胞周期制御による抗体医薬品高生産CHO細胞株構築系の確率,
第65回日本生物工学大会, 73, Sep. 2013.
26. Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
ジェミニ型抗菌剤ハイジェニアとUVA波長光を併用することによる相乗殺菌効果とその殺菌機構の解明,
日本防菌防黴学会第40回年次大会要旨集, No.10Pp-44, 81, Sep. 2013.
27. Yukie Kinoshita, Tomomi Tsutsui, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
抗体生産CHO細胞株におけるNFKBIZ発現の影響,
日本動物細胞工学会2013年度大会(JAACT2013), 68, Jul. 2013.
28. Tomomi Tsutsui, KyoungHo Lee, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
細胞周期エンジニアリングによるChinese hamster ovary (CHO) 細胞における効率的な遺伝子増幅システムの構築,
日本動物細胞工学会2013年度大会(JAACT2013), 50, Jul. 2013.
29. Shizuka Matsumura, Shota Ikawa, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda, Keiji Uchiyama and Takeshi Omasa :
CHO細胞における小胞出芽関連因子Arfのクローニングと発現抑制によるタンパク質生産への影響,
日本動物細胞工学会2013年度大会(JAACT2013), 69, Jul. 2013.
30. Hideaki Maseda :
耐性菌の一生---どこで,どのように生まれ,淘汰されていくのか?,
Japanese Journal of Chemotherapy, May 2013.
31. Akihiko Morishita, Mai Takahashi, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
組換えバイオ医薬品生産CHO細胞株構築過程における染色体不安定性解析,
化学工学会第77年会, Mar. 2013.
32. Masahiro Noda, Miki Tatsuzawa, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
トレハロース添加によるCHO細胞培養過程の抗体凝集抑制,
化学工学会第77年会, Mar. 2013.
33. Yukie Kinoshita, Tomomi Tsutsui, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
NFKBIZ発現による高生産CHO細胞株の構築と解析,
化学工学会第77年会, Mar. 2013.
34. Yuki Ichise, Uwate Maki, Akihiro Shirai, Nakae Taiji and Hideaki Maseda :
緑膿菌mexS遺伝子による多剤耐性化抑制機構の解析,
日本細菌学会, Vol.68, No.1, 195, Mar. 2013.
35. Hideaki Maseda, Uwate Maki, Nakae Taiji, 市瀬 裕樹, Akihiro Shirai and Takeshi Omasa :
緑膿菌多剤耐性株におけるmexS-mexT遺伝子による耐性制御,
第41回薬剤耐性菌研究会, 31, Oct. 2012.
36. Akihiro Shirai, 佐藤 浩一郎, Masayoshi Onitsuka, Hideaki Maseda and Takeshi Omasa :
組換えタンパク質高生産CHO細胞株におけるWFS1発現の影響,
第64回日本生物工学会大会, 33, Oct. 2012.
37. 龍澤 実季, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
トレハロースを用いたCHO細胞培養における抗体の凝集抑制,
第64回日本生物工学会大会, 33, Oct. 2012.
38. 筒井 智美, Akihiro Shirai, Masayoshi Onitsuka, 西沢 明敏, Hideaki Maseda, 本田 孝祐, 大竹 久夫 and Takeshi Omasa :
ATF-4高発現CHO細胞における遺伝子発現解析,
第64回日本生物工学会大会, 33, Oct. 2012.
39. Ami Kuroyama, Uwate Maki, Akihiro Shirai, Nakae Taiji and Hideaki Maseda :
高度多剤耐性緑膿菌nfxC変異株の出現はmexT遺伝子の転写に依存する?,
日本細菌学会, Oct. 2012.
40. Yuko Yokota, Uwate Maki, Akihiro Shirai, Nakae Taiji and Hideaki Maseda :
ダイレクトリピートの欠失による緑膿菌mexT遺伝子出現機構の解析,
日本細菌学会, Oct. 2012.
41. Akihiro Shirai, 遠藤 聡志, Hideaki Maseda and Takeshi Omasa :
チアゾール系新規抗アメーバ剤の抗微生物活性および細胞毒性,
日本防菌防黴学会第39回年次大会要旨集, No.12Pa-01, 157, Sep. 2012.
42. Miki Tatsuzawa, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
CHO細胞培養における凝集体抑制培養:トレハロース添加の影響,
日本生物工学会 西日本支部 第2回講演会, 33, Jul. 2012.
43. Hideaki Maseda, 上手 麻希, Akihiro Shirai and Takeshi Omasa :
緑膿菌多剤耐性株の耐性機構の解析とその性状,
日本生物工学会 西日本支部 第2回講演会, 24, Jul. 2012.
44. 上手 麻希 and Hideaki Maseda :
緑膿菌の多剤耐性株におけるmexS遺伝子の機能解析,
日本化学療法学会雑誌ー第60回 日本化学療法学会学術集会特集号, Vol.60, 253, Mar. 2012.
45. 松本 知浩, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
The effect of medium additive on glycosylation of antibody produced by CHO cell,
第63回日本生物工学会大会講演要旨集, No.1Gp14, 51, Sep. 2011.
46. 帆足 理子, Masayoshi Onitsuka, 木村 修一, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
Construction of mammalian expression vector using gene-amplified structure,
第63回日本生物工学会大会講演要旨集, No.1Gp13, 51, Sep. 2011.
47. Yasunori Kuboyama, Akihiro Shirai, Masayoshi Onitsuka, Satoshi Katsu, 高見 貴之, Hideaki Maseda and Takeshi Omasa :
The effects of CHOP over/down-regulation on recombinant AT-III production,
第63回日本生物工学会大会講演要旨集, No.1Gp12, 51, Sep. 2011.
48. 龍澤 実季, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
トレハロースを用いた細胞培養過程における抗体凝集抑制の検討,
化学工学会第43回秋季大会, 628, Sep. 2011.
49. 遠藤 聡志, Akihiro Shirai, 久保山 泰典, Hideaki Maseda and Takeshi Omasa :
チアゾールを主骨格とする新規抗アメーバ剤の合成とその生物学的特性,
日本防菌防黴学会第38回年次大会要旨集, No.P39-31P, 117, Aug. 2011.
50. 龍澤 実季, Masayoshi Onitsuka, Akihiro Shirai, Hideaki Maseda and Takeshi Omasa :
トレハロース添加による一本鎖二重特異性抗体の凝集抑制効果の検討,
日本農芸化学会中四国支部第30回講演会, 30, May 2011.
51. Akihiro Shirai, Kanae Sakaguchi, Hideaki Maseda, Hiroki Kourai and Takeshi Omasa :
ハイブリッド型第四アンモニウム塩の抗菌特性と安全性,
日本化学会第91春季年会, No.1B5-56, 41, Mar. 2011.
52. 上手 麻希, 市瀬 裕樹, 中江 太治, Takeshi Omasa and Hideaki Maseda :
緑膿菌mexS遺伝子はQuorum-sensing機構を調節する?,
緑膿菌感染症研究会・抄録集, Vol.45, 30, Feb. 2011.
53. 板山 朋聡, 岩見 徳雄, 清水 和也, Niwoot Whangchai, Chayarat Pleumsumran, Sirapran Fakrajang, Suttida Wanno, Ruekeaw Praphrute, Korntip Kammika, Hideaki Maseda, 古澤 文章 and 杉浦 則夫 :
タイ国北部の養魚池における有害藍藻類の発生状況,
日本水処理生物学会誌, No.30, 26, Nov. 2010.
54. 清水 和也, 星 麻里恵, 伊藤 聡, Hideaki Maseda, 岡野 邦宏, 陳 栄志, 内海 真生, 張 振亜 and 杉浦 則夫 :
Microcystin分解産物の特性解析,
日本水処理生物学会誌, No.30, 29, Nov. 2010.
55. 石橋 学, 清水 和也, 小林 弘明, Akihiro Shirai, Takeshi Omasa, 杉浦 則夫 and Hideaki Maseda :
ミクロシスチンの分解に関わるMlrDタンパク質の関与,
日本水処理生物学会誌, No.30, 28, Nov. 2010.
56. 久保山 泰典, Akihiro Shirai, 室巻 良彦, Hideaki Maseda and Hiroki Kourai :
栄養体およびシストアメーバに対する抗アメーバ性試験法とその評価法の確立,
第37回日本防菌防黴学会年次大会, No.2PP-17, 215, Sep. 2010.
57. Akihiro Shirai, 庄野 知明, 布本 泰子, 室巻 良彦, Hideaki Maseda and Hiroki Kourai :
新規チアゾール系抗菌剤の合成とその抗菌特性,
第37回日本防菌防黴学会年次大会, No.1PA-07, 58, Sep. 2010.
58. Akihiro Shirai, 伊藤 優花, Hideaki Maseda and Hiroki Kourai :
ジェミニ型第四アンモニウム化合物を吸着させた無機-有機ハイブリッド抗菌剤の開発,
日本化学会第90春季年会(2010), No.1G7-03, 95, Mar. 2010.
59. 布本 泰子, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
新規アニオン性界面活性剤の開発,
日本防菌防黴学会2009年度若手の会, Dec. 2009.
60. 坂口 香苗, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
新規ハイブリッド型第四アンモニウム塩の合成と抗菌特性,
日本防菌防黴学会2009年度若手の会, Dec. 2009.
61. Akihiro Shirai, 谷村 賢一, 遠藤 聡志, Hideaki Maseda and Hiroki Kourai :
徐放性を付与したポリマー型固定化殺菌剤の構築,
日本防菌防黴学会2009年度若手の会, Dec. 2009.
62. 室巻 良彦, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
Gemini型第四アンモニウム塩の最適構造の検討,
日本防菌防黴学会2009年度若手の会, Dec. 2009.
63. Akihiro Shirai, 大徳 桃子, 大平 匡彦, Hideaki Maseda and Hiroki Kourai :
対称・非対称型ジェミニ新規抗菌剤の合成と抗菌機能,
日本防菌防黴学会2009年度若手の会, Dec. 2009.
64. Akihiro Shirai, 冨脇 真理, 室巻 良彦, Hideaki Maseda and Hiroki Kourai :
抗菌タイマー機能を付与したジェミニ型第四アンモニウム塩の構築,
日本防菌防黴学会2009年度若手の会, Dec. 2009.
65. 大平 匡彦, Akihiro Shirai, Yoichiro Miyake, Hideaki Maseda and Hiroki Kourai :
Synthesis and biological properties of strain-specific peptide derivative modified with a gemini quaternary ammonium salt,
第61回日本生物工学会大会, Sep. 2009.
66. Akihiro Shirai, 黒木 祐輔, Hideaki Maseda and Hiroki Kourai :
新規gemini型ベタインの合成とその殺菌特性,
第36回日本防菌防黴学会年次大会, Sep. 2009.
67. 坂口 香苗, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
新規ハイブリッド型第四アンモニウム塩の合成とその生物学的特性,
第36回日本防菌防黴学会年次大会, Sep. 2009.
68. 筒井 舞子, Akihiro Shirai, 室巻 良彦, Hideaki Maseda and Hiroki Kourai :
Gemini型第四アンモニウム塩による環境病原性アメーバの制御,
第36回日本防菌防黴学会年次大会, Sep. 2009.
69. 室巻 良彦, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
Gemini型第四アンモニウム塩の抗菌活性および細胞毒性評価,
第36回日本防菌防黴学会年次大会, Sep. 2009.
70. 橋田 裕美子, Hideaki Maseda, Akihiro Shirai and Hiroki Kourai :
多剤耐性Serratia marcescens の抗菌剤耐性に関与する遺伝子の同定,
第82回日本細菌学会総会, Mar. 2009.
71. 上手 麻希, Hideaki Maseda, Akihiro Shirai and Hiroki Kourai :
緑膿菌多剤排出ポンプMexEF-OprNの発現制御の解析,
第82回日本細菌学会総会, Mar. 2009.
72. Uwate Maki and Hideaki Maseda :
緑膿菌多剤耐性ポンプMexEF-OprN制御領域の解析,
第43回緑膿菌感染症研究会, 108-116, Feb. 2009.
73. Hideaki Maseda :
クォラムセンシング機構と異物排出システム,
第43回緑膿菌感染症研究会, 27-32, Feb. 2009.
74. Shoko Ueta, 橘 あゆみ, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
真菌類に対するジェミニ型第四アンモニウム塩の作用機構,
日本防菌防黴学会2008年度若手の会, Nov. 2008.
75. 森下 裕生, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
無機/有機ハイブリッド抗菌剤の収着・徐放性に関する研究,
日本防菌防黴学会2008年度若手の会, Nov. 2008.
76. 室巻 良彦, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
ジェミニ型第四アンモニウム塩の安全性評価,
第121回徳島生物学会, Nov. 2008.
77. 清水 和哉, 岡野 邦宏, Hideaki Maseda, 雨宮 崇, 内海 真生 and 杉浦 則夫 :
藍藻由来生物毒microcystin分解酵素遺伝子の転写制御に関する研究,
第45回日本水処理生物学会大会プログラム, No.27, Nov. 2008.
78. 上手 麻希, Hideaki Maseda, Akihiro Shirai and Hiroki Kourai :
緑膿菌多剤排出ポンプMexEF-OprNの発現に及ぼすmvaT遺伝子の効果,
第61回日本細菌学会中国・四国支部総会, Oct. 2008.
79. 橋田 裕美子, Hideaki Maseda, Akihiro Shirai and Hiroki Kourai :
多剤耐性Serratia marcescensの抗菌剤耐性に関与する遺伝子の同定,
第61回日本細菌学会中国・四国支部総会, Oct. 2008.
80. 大徳 桃子, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
新規ハイブリット型第四アンモニウム塩の合成,
第35回日本防菌防黴学会年次大会, Sep. 2008.
81. 冨脇 真理, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
エステル結合型疎水性基を有する新規抗菌剤の合成と抗菌活性,
第35回日本防菌防黴学会年次大会, Sep. 2008.
82. 谷村 賢一, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
徐放型固定化殺菌剤の合成とその特性,
第35回日本防菌防黴学会年次大会, Sep. 2008.
83. 森下 裕生, 室巻 良彦, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
ジェミニ型第四アンモニウム塩の毒性・抗菌活性の定量的構造活性相関解析,
第35回日本防菌防黴学会年次大会, Sep. 2008.
84. 室巻 良彦, Akihiro Shirai, 森下 裕生, Hideaki Maseda and Hiroki Kourai :
ジェミニ型第四アンモニウム塩の環境毒性および抗菌性の評価,
第35回日本防菌防黴学会年次大会, Sep. 2008.
85. Akihiro Shirai, 小野 勉, Hideaki Maseda and Hiroki Kourai :
新規gemini型グリシンベタインの合成とその抗菌特性,
第35回日本防菌防黴学会年次大会, Sep. 2008.
86. Hideaki Maseda :
Quorum-sensing機構の制御と薬剤排出ポンプ,
第22回Bacterial Adherance & Biofilm学術集会, Jul. 2008.
87. Hideaki Maseda, 小林 弘明, 土井 嘉亮, 岡野 邦宏, Hiroki Kourai, 杉浦 則夫 and 小林 達彦 :
ミクロキスチン分解酵素MlrAのトポロジー解析,
大会講演要旨集(2008・名古屋), Mar. 2008.
88. 上野 広太郎, 橋本 義輝, 戸来 幸男, 株本 浩樹, Hideaki Maseda, 東端 啓貴 and 小林 達彦 :
工業的放線菌におけるタンパク質新規生産系,
大会講演要旨集(2008・名古屋), Mar. 2008.
89. 根本 圭美, 八幡 穣, Hideaki Maseda, 野村 暢彦, 中島 敏明 and 内山 裕夫 :
異種細菌由来細胞間シグナル物質によるPseudomonas aeruginosa PAO1株バイオフィルムの抗生物質耐性の制御,
大会講演要旨集(2008・名古屋), Mar. 2008.
90. Hideaki Maseda, 上手 麻希, Akihiro Shirai and Hiroki Kourai :
緑膿菌多剤耐性化遺伝子mexTの機能解析,
第81回日本細菌学会総会, Mar. 2008.
91. Hideaki Maseda, 橋田 裕美子, Akihiro Shirai and Hiroki Kourai :
Serratia marcescensの抗菌剤耐性に関与する遺伝子の同定と解析,
第81回日本細菌学会総会, Mar. 2008.
92. Shoko Ueta, 栗本 麻友子, Tomoko Sumitomo, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
酵母に対するジェミニ型第四アンモニウム塩系薬剤の殺菌機構,
第119回徳島生物学会, Dec. 2007.
93. 倉島 巧, 岡野 邦宏, Hideaki Maseda, 内海 真生 and 杉浦 則夫 :
藍藻類microcystin分解関連酵素群の機能,
第44回日本水処理生物学会大会プログラム, No.27, Nov. 2007.
94. 雨宮 崇, 清水 和哉, 岡野 邦宏, Hideaki Maseda, 内海 真生 and 杉浦 則夫 :
microcystin分解酵素遺伝子の転写に関する研究,
第44回日本水処理生物学会大会プログラム, No.27, Nov. 2007.
95. 松川 雅則, 塚本 泰司 and Hideaki Maseda :
緑膿菌尿分離株における薬剤排出ポンプの発現とバイオフィルム形成能,
第56回日本感染症学会東日本地方会学術集会, Oct. 2007.
96. 辻 陽平, 伊藤 雅代, 延嶋 浩文, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
ジェミニ型第四アンモニウム塩化合物のレジオネラ殺菌に及ぼすCa2+,Mg2+の影響,
日本防菌防黴学会 第34回年次大会, Aug. 2007.
97. 冨脇 真理, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
種々のN-側鎖を有するビス型第四アンモニウム塩の合成とその抗菌活性,
日本防菌防黴学会 第34回年次大会, Aug. 2007.
98. 谷村 賢一, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
第四アンモニウム塩系ポリマー型固定化殺菌剤の合成とその殺菌特性,
日本防菌防黴学会 第34回年次大会, Aug. 2007.
99. 大徳 桃子, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
モノ型とジェミニ型第四アンモニウム塩の抗菌特性の差異,
日本防菌防黴学会 第34回年次大会, Aug. 2007.
100. 森下 裕生, 室巻 良彦, Tomoko Sumitomo, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
ジェミニ型第四アンモニウム塩系薬剤の毒性と化学構造の定量的構造活性相関解析,
日本防菌防黴学会 第34回年次大会, Aug. 2007.
101. 福居 麻弓, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
エーテル結合を有するGemini型第四アンモニウム塩の合成及び殺菌特性の検討,
日本防菌防黴学会 第34回年次大会, Aug. 2007.
102. 岡村 菜穂, Tomoko Sumitomo, 大久保 彰洋, 湯浅 明彦, Akihiro Shirai, Hideaki Maseda and Hiroki Kourai :
魚病細菌に対する光触媒抗菌紙の殺菌特性,
日本防菌防黴学会 第34回年次大会, Aug. 2007.
103. Akihiro Shirai, 栗本 麻友子, Tomoko Sumitomo, Hideaki Maseda and Hiroki Kourai :
酵母に対するジェミニ型ピリジニウム塩系薬剤の殺菌機構,
日本防菌防黴学会 第34回年次大会, Aug. 2007.
104. Hideaki Maseda, 小中 瑠実, Hideaki Nagamune, Tomoko Sumitomo, Takuya Maeda and Hiroki Kourai :
Serratia marcescens の消毒剤および抗生物質に対する耐性機構の解明,
日本細菌学会, Mar. 2007.
105. Hideaki Maseda :
微生物の応答と制御,
日本農芸化学会北海道・東北支部合同若手シンポジウム, Nov. 2006.
106. 古小路 夏美, Tomoko Sumitomo, Hideaki Maseda, Takuya Maeda and Hiroki Kourai :
多剤交叉耐性Achromobacter sp.の耐性化機構の解明,
日本防菌防黴学会2006年度若手の会, Oct. 2006.
107. 北浦 真希, Tomoko Sumitomo, Takuya Maeda, Hideaki Maseda and Hiroki Kourai :
セラチアに対するジェミニ型第四アンモニウム塩系薬剤の殺菌機構の解明,
日本防菌防黴学会2006年度若手の会, Oct. 2006.
108. Shoko Ueta, Mayuko Kurimoto, Tomoko Sumitomo, Takuya Maeda, Hideaki Maseda and Hiroki Kourai :
酵母に対するジェミニ型第四アンモニウム塩系薬剤の殺菌機構,
日本防菌防黴学会2006年度若手の会, Oct. 2006.
109. 岡村 菜穂, Tomoko Sumitomo, Takuya Maeda, Hideaki Maseda and Hiroki Kourai :
gemini型第四アンモニウム塩の枯草菌(Bacillus subtilis)に対する殺菌機構の解明,
日本防菌防黴学会2006年度若手の会, Oct. 2006.

Et cetera, Workshop:

1. Akihiro Shirai, Kyohei Matsumura, Masato Kajiura, Hideaki Maseda and Takeshi Omasa :
LED光殺菌に及ぼす有機系抗菌剤の相乗効果,
平成26年度革新的特色研究シンポジウム LEDライフフォトニクス研究プロジェクト・LEDライフイノベーション研究プロジェクト, Feb. 2015.
2. Hideaki Maseda :
日和見感染菌の抗菌剤耐性機構の解明と制御,
May 2008.

Patent:

1. Hideaki Maseda and 上手 麻希 : タンパク質発現方法, (Jul. 2015), 2015-149826 (Jul. 2015).
2. Hideaki Maseda, 上手 麻希 and 菅野 茂夫 : 新規発現誘導システムを可能する真核細胞発現カセット, (Jun. 2015), 2015-111458 (Jul. 2015).
3. Hideaki Maseda and 上手 麻希 : 薬剤耐性化抑制剤の候補物質のスクリーニング方法, (Jan. 2015), 2014-016816 (Jan. 2015).
4. Hideaki Maseda and 上手 麻希 : 発現カセット, (Jan. 2015), PCT/JP2015/52727 (Jan. 2015).
5. Hideaki Maseda and 上手 麻希 : 発現カセット, (Jan. 2014), 2014016814 (Jan. 2014).
6. Hiroki Kourai, Hideaki Maseda and Akihiro Shirai : ペプチド, 2009-65464 (Mar. 2009), 2009-254355 (Nov. 2009), .
7. 小林 達彦, Hideaki Maseda, 武井 謙典 and 藤田 理英子 : 新規物質TMR, 2006-81893 (Mar. 2006), 2007-254399 (Oct. 2007), .
8. 小林 達彦, 橋本 義輝, 東端 啓貴 and Hideaki Maseda : ストレプトマイセス属微生物における遺伝子高発現系, 2005-244690 (Aug. 2005), 2007-53994 (Mar. 2007), .
9. 小林 達彦, 橋本 義輝, 東端 啓貴, Hideaki Maseda and 西矢 芳昭 : タンパク質を製造する方法, 2005-227282 (Aug. 2005), 2007-37498 (Feb. 2007), .
10. 小林 達彦, 橋本 義輝, 東端 啓貴 and Hideaki Maseda : シャトルベクター, 2004-380940 (Dec. 2004), 2006-180843 (Jul. 2006), .
11. 野村 暢彦 and Hideaki Maseda : 細胞膜間の物質輸送を促進する薬剤, 2002-260338 (Sep. 2002), 2004-97030 (Apr. 2004), .
12. 野村 暢彦 and Hideaki Maseda : 排出ポンプ阻害剤をスクリーニングする方法, 2002-260386 (Sep. 2002), 2004-97031 (Apr. 2004), .

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 生来の腸内細菌に着目した微小動物の形質制御技術の開発と水質浄化への応用 (Project/Area Number: 18H03396 )
  • Determination of PODiR signaling pathway (Project/Area Number: 17K08832 )
  • Magnetic separation of antibioitics for the prevention of antibiotic resistant bacteria in the livestock environment (Project/Area Number: 16H05004 )
  • Elucidation of the mechanism of serotonin accumulation in rice root; A suppression of serotonin concentration during a primary stage. (Project/Area Number: 15H04462 )
  • Development of aquatic environment restoration technology using molecular breeding strain of cyanotoxin-degrading bacteria (Project/Area Number: 15H02840 )
  • Elucidation of gene appearance mechanism in genome (Project/Area Number: 26460529 )
  • Investigation on the actual condition of microorganisms with disability to purification treatment using ecogenomics in polluted freshwater sources in Malaysia (Project/Area Number: 26304002 )
  • Analysis on the effect of Global Warming for aquaculture ponds at different Altitudes using Environmental Genomics (Project/Area Number: 25303021 )
  • Analysis of musty odor production in the freshwater environment and development of its occurrence suppression scheme (Project/Area Number: 25281042 )
  • Development of new bacterial control system (Project/Area Number: 23590512 )
  • Elucidation of the nourishment condition improvement mechanism of the host plant by infestation of an aphid: Selective accumulation of the amino acid (Project/Area Number: 23580074 )
  • Next generation protein production on cellular quality-control process (Project/Area Number: 23360371 )
  • Construction of a new technology and science education system (Project/Area Number: 21500878 )
  • Metal Surface Modification to Moderate Marine Biofilm Formation And the Clarification of Moderation Mechanism (Project/Area Number: 21360372 )
  • Elucidation of microbial cyanotoxin degradation mechanism and use the knowledge for aquatic environment treatment application (Project/Area Number: 21310049 )
  • Development of quorum quenchers for the control of multidrug resistant strains (Project/Area Number: 20590447 )
  • 未来型バイオプロスペクティングの技術創成のための企画調査 (Project/Area Number: 17638003 )
  • 緑膿菌多剤排出ポンプの発現機構の解明とその制御 (Project/Area Number: 16790251 )
  • アーキアにおけるRNA末端形成システムの解明 (Project/Area Number: 16658033 )
  • Functional analysis of non-proteolytic enzymes involved in carbon-nitrogen bond cleavage (Project/Area Number: 14360047 )
  • Search by Researcher Number (10372343)