Induced expression of a subtilisin-like proprotein convertase PACE4 in the regeneration model of rat submandibular gland.

The 4th International Symposium on Salivary Glands in Honor of Niels Stensen


Sexual difference in the regeneration model of the rat submandibular gland.


Post-translational modifications of water channel aquaporin-5 in salivary gland cells, Oral Neuroscience 2016


Synaptic plasticity in the brain -Roles of NMDA receptor- (Invited lecture at Nantong University)


The Defense System of Oral Cavity: Lipopolysaccharide Induced Inflammatory Response in the Mice Salivary Gland

BIT's 1st Annual International Congress of Oral & Dental Medicine, Session 9: Oral Immunological Diseases, Allergy and Inflammation


Salivary Gland Development, Differentiation, and Regeneration - Role of Subtilisin-like Proprotein Convertase PACE4/SPC4

BIT's 1st Annual International Congress of Oral & Dental Medicine, Session 3: Oral Biology


Effects of natural point mutation of rat aquaporin 5 expressed in vitro on its capacity of water permeability and membrane trafficking

The Journal of Medical Investigation : JMI

In the colony of Sprague-Dawley (SD) strain, we found that there were rats expressing a mutant AQP5, which has a point mutation at nt 308 (G308A), leading to a replacement of (103)Gly with (103)Asp in the 3rd transmembrane domain. The mutant molecule scarcely expressed in the acinar cells, probably because of ineffective trafficking. The mutant molecule, however, showed normal water permeability when assessed by the oocyte system.


Induction of calprotectin mRNAs by lipopolysaccharide in the salivary gland of mice

Calprotectin is a major cytosolic calcium-binding protein of leukocytes which belongs to the S100 protein family. S100A8 and S100A9, major types of calprotectin are heterodimeric complexes being composed of light- and heavy-chain subunits. The calprotectin levels in the plasma, feces, synovial fluid, gingival crevicular fluid, dental calculus and saliva change when the host animal suffers from several inflammatory diseases. Members of Toll-like receptor (TLR) family are pattern-recognition receptors for lipopolysaccharide (LPS) and other pathogens. Here we examined if the biological role of TLR receptor is reflected to the calprotectin expression in the salivary gland. Time course study by using real-time RT-PCR detected higher levels of S100A8 and S100A9 mRNA at 1.5-3 h after injection of LPS in both the submandibular gland (SMG) and parotid gland (PG) of C3H/HeN mice but not in the same tissues of C3H/HeJ, a TLR-4 mutant strain, indicating that this induction is mediated via the TLR-4. These results indicate that, an inflammatory marker, calprotectin, is expressed in the mouse salivary gland and that LPS stimulated its synthesis. Calprotectin (S100A8/A9) showed minimum expression in all cellular segments in the SMG except excretory duct cells, which showed strong signal at the cytoplasm. LPS induced their expressions in the granular convoluted tubular cells and striated duct cells. In the PG, these proteins were expressed very weakly in both duct and acinar cells with a little stronger staining for the former cells. LPS injection induced calprotectin (S100A8/A9) in both duct and acinar cells especially in the former cells.


Down-regulation of submandibular gland AQP5 following parasympathetic denervation in rats

Following chorda tympani denervation (CTD, parasympathetomy), the protein levels of aquaporin5 (AQP5) as well as AQP1 and Na(+)K(+)ATPase alpha-subunit in the rat submandibular gland (SMG) were found to be decreased significantly. However, the level of another membrane protein, dipeptidyl peptidase IV was not affected by CTD, suggesting a selective reduction of AQP5, AQP1, and Na(+)K(+)ATPase alpha -subunit proteins by CTD. However, the AQP5 mRNA level was scarcely affected by CTD, which suggested that transcription process of AQP5 was unaffected by this operation. AQP5 protein was shown to be degraded in vitro by the extract of the SMG obtained from normal rat; inhibitor experiments in vitro suggested cathepsin B was a responsible enzyme. Co-localization of AQP5 and LAMP-2, a lysosomal marker, implicated AQP5 is degraded in lysosomes. A significant increase in the protein levels of LC3-II, an autophagy marker, at day 1 after CTD, and co-localization of the LC3 protein and AQP5, suggested that CTD activated autophagy of SMG, leading to AQP5 degradation.


Involvement of the IL-6/STAT3/Sca-1 system in proliferation of duct cells following duct ligation in the submandibular gland of mice

Ligation of the main excretory duct (MED) of the mouse submandibular gland (SMG) induced the expression of Sca-1, a stem cell marker. Sca-1 expression increased prominently in almost all of cells in the duct system, except the acinar cells. Sca-1 induction was accompanied with phosphorylated-STAT3 (Y705) elevation, which was localized in the nuclei of all duct cells. Electrophoretic mobility shift assay (EMSA) confirmed the specific binding of STAT3 to the GAS sequence, a biding site of gamma interferon activating site. Present study suggested one of the initial steps of the tissue regeneration after injury includes STAT3 pathway.


Salivary Gland Development: Its mediation by a subtilisin-like proprotein convertase, PACE4

The submandibular gland (SMG) develops under the epithelial-mesenchymal interaction. Its process is regulated by various growth/differentiation factors, which are synthesized as inactive precursors and activated via the limited proteolysis at their multi basic amino acid site(s) such as Arg-X-Lys/Arg-Arg. Although many of these processing steps are elucidated to be catalyzed by subtilisin-like proprotein convertases (SPCs), little is known about the role of SPCs in the SMG development. Here, we focused upon the physiological role of PACE4 (SPC4), a member of SPC family, in the SMG development. In the organ culture system of rat embryonic SMG (E15), Dec-RVKR-CMK, a potent inhibitor for SPCs, inhibited the salivary branching and the expression of an exocrine gland type water channel, AQP5. However, other peptidyl-CMKs and inhibitors for trypsin-like serine proteases including leupeptin did not affect the salivary branching and AQP5 expression. Dec-RVKR-CMK also suppressed the expression of PACE4, but not furin, another member of the family. The specific antibody for the catalytic domain of PACE4 suppressed the salivary branching and AQP5 expression similarly. These inhibitory effects of Dec-RVKR-CMK were partially rescued by the addition of recombinant BMP2 whose precursor is a candidate for the physiological substrates of PACE4. Further, the transcriptional silencing of PACE4 by its specific siRNAs caused the suppression of both the salivary branching and AQP5 expression in the present organ culture system. These observations strongly support the idea that PACE4 mediates the SMG development.


Aquaglyceroporins are involved in uptake of arsenite into murine gastrointestinal tissues

Aquaglyceroporins (AQGPs) are members of aquaporin (AQP) family and belong to a subgroup of this water channel family; they are transmembrane proteins that transport water as well as glycerol and other solutes of small molecules. Recent studies have also identified that AQGPs are important transporters of trivalent metalloid in some mammalian cells. However, the uptake routes of arsenite in mammals are still less defined. In this study, to understand the routes of arsenite intake in mammals, mice were treated with Hg(II), glycerol, and As(III) and uptake of As(III) into the gastrointestinal tissues was measured. The level of inorganic arsenic (iAs) in gastrointestinal tissues after As(III) stimulation was much higher than Hg(II) +As(III) or glycerol+As(III) group. RT-PCR results showed that AQGPs were extensively expressed in gastrointestinal tissues of mice. We also treated Caco-2 cells with Hg(II) and As(III); the level of iAs in a group treated with Hg(II)+As(III) decreased compared with As(III)-treated group. Our results suggested that AQGPs could be important transporters in arsenite uptake into gastrointestinal tissues of mice, but more data are need to prove if AQGPs is the only pathway involved in As transport in mammals or just one of them.


Potential down-regulation of parotid gland AQP5 by LPS via cross-coupling of NF-κB/AP1

The 11th International Symposium on Exocrine Secretion, Tokushima 09 ''Exocrine Secretion Mechanism and Disease''


Is AQP5 down-regulated via autophagic pathway following chorda tympani denervation?

The International Symposium on Oral Sciences to Improve the Quality of Life, organized by Toshihiko Nagata


Analyses of rat AQP5 G103D mutant expressed in MDCK-II cells and Xenopus oocytes


Activation of IL-6/STAT3/Sca-1 system induces proliferation of duct cells in the duct-ligated mouse submandibular gland

The 2nd International Symposium on The Future Direction of Oral Sciences in The 21st Century-Oral Sciences for Our Healthy Life-, organized by Toshihiko Nagata


A naturally occurring point mutation in rat AQP5 influencing its membrane trafficking in and water secretion from salivary gland

The 5th International Conference of Aquaporin


Effects of autonomic denervation and administration of M3 muscarinic receptor agonist on the AQP5 expression in the rat submandibular gland


LPS induces down-regulation of AQP5 and AQP1 via Nf-kB and MAPK pathways in the mouse parotid gland


Prenatal expression of rat salivary AQP5 is dependent on the submandibular gland development mediated by a subtilisin-like proprotein convertase PACE4


Alterations of AQP5, cellular markers of duct, and Sca-1 expression in the duct-ligated mouse submandibular gland


Point mutation of AQP5 in Sprague-Dawley rats and its implication for salivary gland physiology

The 1st International Symposium and Workshop on The Future Direction of Oral Sciences in The 21st Century, organized by Bando, E.


Effects of autonomic denervation and administration of muscarinic receptor agonist on the expression of AQPs in the rat submandibular gland


Changes of cellular markers of duct/acinni and side populations in the duct-ligated mouse submandibular gland


Molecular and cellular analyses of mutant AQP5 which occurred naturally in Spraque - Dawley rats

3rd International Symposium on Salivary Glands in Honor of Niels Stensen


Effects of autonomic denervation and administration of SNI-2011 on the expression of AQPs in the rat salivary gland

The 3rd International Symposium on Salivary Glands in honor of Niels Stensen


Tissue kallikrein mK13 is a candidate of the processing enzyme for pro-IL-1β in the mouse submandibular gland


Involvement of a subtilisin-like proprotein convertase, PACE4, in branching morphogenesis and AQP5 expression in the rat embryonic submandibular gland.


The expression of cellular markers of duct/acini and side population dynamics in the duct-ligated mouse submandibular gland.


Proteolytic processing of the precursor of interleukin-1β by tissue kallikrein mK13 in the submandibular gland of mice.

International symposium on "Medical and Biological Perspectives in Proteases and Their Inhibitors", Satellite meeting of the 20th IUBMB International Congress of Biochemistry and Molecular Biology & the 11th FAOBMB Congress


Inhibition of subtilisin-like proprotein convertase PACE4 reduces the branching morphogenesis and expression of AQP5 in the organ culture system of rat embryonic submandibular gland


サチライシン様前駆体蛋白質変換酵素PACE4の阻害はラット胎仔顎下腺の分枝形成とAQP5発現を抑制する

20th IUBMB International Congress of Biochemistry and Molecular Biology & 11th FAOBMB Congress, 第79回日本生化学会大会 & 第29回日本分子生物学会年会, also 第59回日本細胞生物学会大会


Induction, processing, and secretion of IL-1βin the submandibular gland of mice

The 35th International Congress of Physiological Sciences (IUPS2005) and Experimental Biology 2005


ECM-bound proprotein convertase PACE4 is involved in the branching morphogenesis of rat submandibular gland


コオロギ食が唾液腺機能に及ぼす効果の検証

コオロギ食が唾液腺機能に及ぼす効果の検証

第1回唾液ケア研究会学術集会

第1回唾液ケア研究会学術集会


食品成分が唾液腺機能に及ぼす影響

食品成分が唾液腺機能に及ぼす影響


マウス唾液腺AQP5発現に及ぼす高脂肪食および低タンパク質食摂取の影響

マウス唾液腺AQP5発現に及ぼす高脂肪食および低タンパク質食摂取の影響

第63回歯科基礎医学会学術大会

第63回歯科基礎医学会学術大会

徳島県徳島市(徳島大学)

徳島県徳島市(徳島大学)


周辺環境が主観的感覚および摂食行動に及ぼす影響:筋電図を用いた研究

周辺環境が主観的感覚および摂食行動に及ぼす影響:筋電図を用いた研究

日本味と匂学会第55回大会

日本味と匂学会第55回大会


Relationship between brain activities and feeding behavior under comfortable and uncomfortable environments.

快・不快環境下における脳活動と摂食行動の関連性

第55回日本味と匂い学会

第55回日本味と匂い学会


高脂肪食や低タンパク質食が引き起こすマウス唾液腺AQP5発現・局在変化

高脂肪食や低タンパク質食が引き起こすマウス唾液腺AQP5発現・局在変化

第75回日本栄養・食糧学会大会

第75回日本栄養・食糧学会大会


Localization of subtilisin-like proprotein convertase PACE4 in the course of development of the rat submandibular gland

サチライシン様前駆体蛋白質変換酵素PACE4のラット顎下腺発生過程における局在

第62回歯科基礎医学会学術大会

第62回歯科基礎医学会学術大会


Localization of subtilisin-like proprotein convertase PACE4 during development of the rat salivary gland

ラット唾液腺発生過程におけるサチライシン様前駆体蛋白質変換酵素PACE4の局在

第93回日本生化学会大会

第93回日本生化学会大会


Increase in theta-band EEG activities under tasting chocolate with unmatched odor stimulation

第41回日本神経科学大会

第41回日本神経科学大会


Theta band brain activity during checking the unmatched olfactory-taste information

匂いと味の不一致が引き起こすシータ波領域脳活動


甘味とニオイのミスマッチが甘味認知に与える影響

甘味とニオイのミスマッチが甘味認知に与える影響

第69回日本生理学会中国・四国地方会

第69回日本生理学会中国・四国地方会


唾液腺再生モデルにおける雌雄差の影響

唾液腺再生モデルにおける雌雄差の影響

第69回日本生理学会中国・四国地方会

第69回日本生理学会中国・四国地方会


Influences of Match/Mismatch of taste and odor on taste perception: An electroencephalogram frequency analysis study

味と匂いのミスマッチが味覚認知に与える影響:脳波周波数分析を用いた研究

日本味と匂学会第51回大会

日本味と匂学会第51回大会


カフェイン投与により誘発される視覚野オシレーション におけるnon-NMDA受容体とNMDA受容体の相互交錯的関与

第40回日本神経科学大会

第40回日本神経科学大会


Influences of olfactory stimulation on taste perception: An electroencephalogram frequency analysis study

The 94th Annual Meeting of the Physiological Science of Japan


Sexual difference in regeneration of salivary gland

唾液腺再生過程で見られる雌雄差について

第58回歯科基礎医学会学術大会

第58回歯科基礎医学会学術大会


Induction of a subtilisin-like proprotein convertase PACE4 in regeneration model of salivary gland Part II

唾液腺再生モデルにおけるサチライシン様前駆体蛋白質変換酵素PACE4の発現誘導-Part II-

第58回歯科基礎医学会学術大会

第58回歯科基礎医学会学術大会


Influences of oral impairment on neural oscilltion and wave propagation in the neocortex of rats

第38回日本神経科学大会

第38回日本神経科学大会


Expression of water channel AQP5 in regeneration model of salivary gland

唾液腺再生モデルにおける水チャネルAQP5の発現

福岡国際会議場, 福岡県

福岡国際会議場, 福岡県


Enhanced ubiquitylation and downregulation of aquaporin-5 by ubiquitin ligases

ユビキチンリガーゼによるAQP5のユビキチン化亢進とダウンレギュレーション

福岡国際会議場, 福岡県

福岡国際会議場, 福岡県


Induced expression of subtilisin-like proprotein convertase in regeneration model of salivary gland

唾液腺再生モデルにおけるサチライシン様前駆体蛋白質変換酵素の発現誘導

第56回歯科基礎医学会(福岡国際会議場/福岡県)

第56回歯科基礎医学会(福岡国際会議場/福岡県)


Involvment of subtilisin-like proprotein convertase PACE4 in regeneration of salivary gland

唾液腺再生におけるサチライシン様前駆体蛋白質変換酵素PACE4の関与

岡山コンベンションセンター/岡山県

岡山コンベンションセンター/岡山県


ヒト唾液腺HSG細胞における構成的なAQP5の取り込み

ヒト唾液腺HSG細胞における構成的なAQP5の取り込み

岡山コンベンションセンター/岡山県

岡山コンベンションセンター/岡山県


唾液腺再生におけるサチライシン様前駆体蛋白質変換酵素PACE4の関与


唾液腺再生におけるサチライシン様前駆体蛋白質変換酵素PACE4の関与

岡山コンベンションセンター/岡山県

岡山コンベンションセンター/岡山県


ラット大脳皮質におけるnon-NMDA受容体活動に依存する20Hzオシレーション

国立京都国際会館/京都府

国立京都国際会館/京都府


ヒト唾液腺HSG細胞における構成的なAQP5の取り込み

ヒト唾液腺HSG細胞における構成的なAQP5の取り込み


唾液腺細胞におけるアクアポリン5の翻訳後修飾

唾液腺細胞におけるアクアポリン5の翻訳後修飾

第53回歯科基礎医学会学術大会 サテライトシンポジウムSS11

第53回歯科基礎医学会学術大会 サテライトシンポジウムSS11


唾液腺細胞におけるアクアポリン5の翻訳後修飾 --- 第53回歯科基礎医学会学術大会(2011年9月30日-10月2日)サテライトシンポジウムSS11


Calprotectin expression in the mouse salivary gland: Induction by lipopolysaccharide


唾液腺細胞におけるアクアポリン5リン酸化のシグナル伝達機構

唾液腺細胞におけるアクアポリン5リン酸化のシグナル伝達機構


アクアポリン5のユビキチン化とその細胞内膜輸送系における役割

アクアポリン5のユビキチン化とその細胞内膜輸送系における役割


Calprotectin induction by lipopolysaccharide in the salivary gland of mice

マウス唾液腺でのリポ多糖によるカルプロテクチン誘導


AQP5 degradation via autophagy following parasympathetic denervation in the rat SMG.

ラット顎下腺での副交感神経切除に続くオートファジーを介したAQP5分解


An AQP5 G103D mutant found in SD rats shows normal water permeability but reduced membrane trafficking

SDラットで見られるAQP5 G103D変異は正常な水透過性を示すが，膜へのトラフィッキングが低下した


Down regulation of submandibular gland AQP5 by chorda tympany denervation

副交感神経切除による顎下腺AQP5のダウンレギュレーション


Involvement of IL-6-STAT3-Sca-1 system in the proliferation of duct cells in the ligated mouse submandibular gland

導管結紮マウス顎下腺における導管細胞の増殖へのIL-6-STAT3-Sca-1系の関与


LPSによる耳下腺AQP5の発現制御とそのシグナル伝達経路

LPSによる耳下腺AQP5の発現制御とそのシグナル伝達経路

第59回日本生理学会中国四国地方会

第59回日本生理学会中国四国地方会


唾液腺腺房細胞の発生・分化・成熟化と水チャネルAQP5発現

唾液腺腺房細胞の発生・分化・成熟化と水チャネルAQP5発現

第59回日本生理学会中国四国地方会

第59回日本生理学会中国四国地方会


Transient increase in IL-6 by duct ligation leading to continuous elevation of Sca-1, a stem cells marker, in the mouse submandibular gland

導管結紮によるマウス顎下腺での一過性のIL-6の増加が幹細胞マーカーSca-1の持続的な上昇を引き起す

第49回歯科基礎医学会学術大会

第49回歯科基礎医学会学術大会


Analyses of function of rat mutant AQP5 expressed in MDCK II cells

MDCK II細胞で発現させたラット変異AQP5の機能解析


Regulation of submandibular gland AQP5 protein expression by lysosomal system

リソゾーム系による顎下腺AQP5蛋白質発現の調節


唾液腺腺房細胞の分化とAQP5発現

唾液腺腺房細胞の分化とAQP5発現


Functional analyses of rat mutant AQP5 expressed in vitro system and it's implication to abnormal saliva secretion

in vitroシステムで発現したラット変異AQP5の機能解析と異常唾液分泌への影響


ラット唾液腺AQP5，AQP1，及びリソゾーム酵素系に対する自律神経切除とSNI2011投与の影響


LPSによる唾液腺AQP5およびAQP1の発現制御とそのシグナル伝達経路

LPSによる唾液腺AQP5およびAQP1の発現制御とそのシグナル伝達経路


顎下腺の分枝形成とAQP5発現は前駆体蛋白質変換酵素PACE4により調節される

顎下腺の分枝形成とAQP5発現は前駆体蛋白質変換酵素PACE4により調節される


Effect of duct ligation on the expression of cellular markers of duct/acini and side population dynamics of the mouse submandibular gland

マウス顎下腺における腺房細胞/導管細胞マーカーの発現，およびサイドポピュレーション細胞群の挙動に及ぼす主導管結紮の影響

第48回歯科基礎医学会学術大会

第48回歯科基礎医学会学術大会


第28回分子生物学会年会, ワークショップW3G「プロテアーゼによる細胞分化・機能制御, 植物から動物まで/Proteases as biomodulators in bacteria, plant and animal」


Effects of sympathectomy, parasympathectomy, administration of SNI-2011 on the expression of AQP5 and AQP1 in the rat submandibular gland

交感神経切除，副交感神経切除，およびSNI-2011投与のラット顎下腺におけるAQP5，AQP1発現におよぼす影響

第78回日本生化学会大会

第78回日本生化学会大会


Kallikrein mK13 is a candidate of pro-IL-1βprocessing enzyme in the mouse salivary gland

カリクレインmK13はマウス唾液腺におけるpro-IL-1βプロセシング酵素の候補である

第78回日本生化学会大会

第78回日本生化学会大会


Developmental regulation of the submandibular gland by ECM-bound proprotein convertase PACE4

ECM結合型前駆体蛋白質変換酵素PACE4による顎下腺発生過程の調節

第78回日本生化学会大会

第78回日本生化学会大会


ラット顎下腺AQP5並びにAQP1に対する交感神経切除・副交感神経切除及びSNI-2011投与の影響


マウス唾液腺カリクレインmK13はpro-IL-1βプロセシング酵素の候補である


顎下腺発生における前駆体蛋白質変換酵素PACE4の関与

顎下腺発生における前駆体蛋白質変換酵素PACE4の関与


外分泌腺における水チャネル，アクアポリンの発現と機能調節

外分泌腺における水チャネル，アクアポリンの発現と機能調節

第47回歯科基礎医学会サテライトシンポジウム「唾液分泌機構研究の最近の進歩」

第47回歯科基礎医学会サテライトシンポジウム「唾液分泌機構研究の最近の進歩」


ECM-bound proprotein convertase PACE4 is a candidate regulator in the branching morphogenesis of rat submandibular gland

ECM結合型前駆体蛋白質変換酵素PACE4はラット顎下腺の分枝形成における調節因子候補である

第77回日本生化学会大会

第77回日本生化学会大会


マウス顎下腺におけるカリクレインmK13によるpro-IL1βの活性化

マウス顎下腺におけるカリクレインmK13によるpro-IL1βの活性化


顎下腺の分枝形成と機能発現

顎下腺の分枝形成と機能発現


水チャネル，アクアポリンの外分泌腺における発現と機能調節

水チャネル，アクアポリンの外分泌腺における発現と機能調節

第45回日本生化学会中国・四国支部例会

第45回日本生化学会中国・四国支部例会


ラット顎下腺の発生・分化・成熟と機能発現

ラット顎下腺の発生・分化・成熟と機能発現

第45回日本生化学会中国・四国支部例会

第45回日本生化学会中国・四国支部例会


実験的炎症による唾液腺サイトカインの誘導

実験的炎症による唾液腺サイトカインの誘導


Jumping: An index behavior for the epileptic family of Mongolian gerbil. (Preliminary report)

ジャンピング:てんかん家系スナネズミに対する行動指標(プレリミナリーレポート)

第26回日本神経科学大会

第26回日本神経科学大会


ラット顎下腺発生過程でのAQPsの発現と局在

ラット顎下腺発生過程でのAQPsの発現と局在

第75回日本生化学会大会

第75回日本生化学会大会


Divergent gene expression and localization of aquaporin 5 in the submandibular gland of Sprague-Dawley rats

Sprague-Dawleyラット顎下腺におけるAQP5の相違する遺伝子発現と局在


ラット顎下腺発生過程でのAQPsの発現と局在

ラット顎下腺発生過程でのAQPsの発現と局在


病態モデルスナネズミ近交化の試み(中間報告)

病態モデルスナネズミ近交化の試み(中間報告)

第25回日本神経科学大会

第25回日本神経科学大会


マウス耳下腺における水チャネルAQP5のイソプロテレノールによるdouwn-regulationの機構


イソプロパノール反復投与によるマウス唾液腺機能に及ぼす影響

イソプロパノール反復投与によるマウス唾液腺機能に及ぼす影響


Induction of a subtilisin-like proprotein convertase PACE4 in regeneration model of salivary gland Part II

唾液腺再生モデルにおけるサチライシン様前駆体蛋白質変換酵素PACE4の発現誘導-Part II-


Sexual difference in regeneration of salivary gland

唾液腺再生過程で見られる雌雄差について


唾液腺再生への subtilisin-like proprotein convertase PACE4の関与

自然科学研究機構生理学研究所研究会「唾液腺形態形成研究会~機能解析から器官再生へ~」

自然科学研究機構生理学研究所研究会

自然科学研究機構生理学研究所研究会


細胞内cAMP上昇が大脳皮質味覚野から口腔体性感覚野への信号伝播速度に与える影響