mihachie/published_papers/15839552 Chie Wada-Mihara Hiroyuki Seto Hirofumi Ohba Kaku Tokunaga Jun-ichi Kido Toshihiko Nagata Koji Naruishi Local administration of calcitonin inhibits alveolar bone loss in an experimental periodontitis in rats Elsevier Masson SAS Biomedicine and Pharmacotherapy 1950-6007 97 1 765 770 20180101 10.1016/j.biopha.2017.10.165 29107933 2-s2.0-85032653167 mihachie/published_papers/15839553 Chie Mihara-Wada 美原(和田) 智恵 Koji Naruishi 成石浩司 Mika Bandou 板東美香 Nishikawa Yasufumi 西川泰史 Jung-Hwan Lew Eijiro Sakamoto 坂本英次郎 Ikuta Takahisa 生田貴久 Kono Kaoru 河野薫 Yukari Kajiura 梶浦由加里 Hashimoto Mari 橋本万里 Yukiko Nakajima 中島由紀子 Yuji Inagaki 稲垣裕司 Masami Ninomiya 二宮雅美 Jun-ichi Kido 木戸淳一 Toshihiko Nagata 永田俊彦 Post clinical clerkship-OSCEを見据えた歯周病科での模擬OSCEの概要 Journal of Oral Health and Biosciences 2188-7888 29 2 49 53 20170200 10.20738/johb.29.2_49 mihachie/published_papers/15839561 Jun-ichi Kido 木戸淳一 Mika Bandou 板東美香 Yuji Inagaki 稲垣裕司生田貴久 Yukari Kajiura 梶浦由加里 Yukiko Nakajima 中島由紀子 Eijiro Sakamoto 坂本英次郎 Chie Mihara-Wada 美原(和田) 智恵 Masami Ninomiya 二宮雅美西川泰史 Jung-Hwan Lew Koji Naruishi 成石浩司 Toshihiko Nagata 永田俊彦 Diagnosis of Periodontal Diseases using Biomarkers in Gingival Crevicular Fluid 歯肉溝滲出液中のバイオマーカーを用いた歯周病診断 Periodontal diseases cause an inflammation and degradation of periodontal tissues and missing of teeth. The incidence rate of periodontal diseases is high in middle-aged and elderly people.A reasonable diagnosis of periodontal diseases is very important to keep teeth, however, conventional examinations of periodontal diseases is not necessarily exact and objective. Gingival crevicular fluid (GCF) is an exudate secreted from periodontal tissues and contains many components including proteolytic enzymes, inflammatory cytokines, blood-associated proteins, cellular and bacterial fragments. Because some proteins in GCF are related to inflammation, tissue degradation and bone metabolism, those proteins have been studying as a diagnostic marker of periodontal diseases. GCF is noninvasively collected using a sterile paper strip and biomarkers are determined using enzyme-linked immunosorbent assay (ELISA) and enzyme activity assay. We identified calprotectin, an inflammationrelated protein, in GCF and calprotectin level in GCF from periodontitis sites was significantly higher than that of healthy control. Calprotectin level in GCF was positively correlated to gingival index and other biomarkers and decreased by periodontal treatments. Resistin is an adipocytokine and its level increases in some inflammatory diseases. Resistin level in GCF from periodontitis sites was high compared to the level of healthy control samples. Procollagen type I C-terminal peptide (PICP) is a biomarker for bone metabolism and its level was high in GCF collected from periodontitis sites. These results suggested that calprotectin, resistin and PICP are useful biomarkers for periodontal diseases. On the other hand, we showed that glycated albumin (GA), a marker of diabetes mellitus (DM), was contained in GCF and GA level in GCF from DM patients was significantly higher than that of non-DM individuals. Components in GCF may be biomarkers of systemic diseases as well as periodontal diseases and their determination will be useful diagnostic examination of some diseases. Recently, we have been studying the determining system of GCF calprotectin, including microchip ELISA, surface plasmon resonance assay and immuno-chromatography assay. When GCF biomarkers are determined using the determining systems, we will simply, exactly and objectively diagnose periodontal diseases at our dental offices. Journal of Oral Health and Biosciences 2188-7888 29 1 13 20 20161200 mihachie/published_papers/28148787 E. Sakamoto C. Mihara T. Ikuta Y. Inagaki J. Kido T. Nagata Inhibitory effects of advanced glycation end-products and Porphyromonas gingivalis lipopolysaccharide on the expression of osteoblastic markers of rat bone marrow cells in culture JOURNAL OF PERIODONTAL RESEARCH 1600-0765 51 3 313 320 20160600 10.1111/jre.12310 mihachie/published_papers/15839554 E. Sakamoto C. Mihara T. Ikuta Y. Inagaki J. Kido T. Nagata Inhibitory effects of advanced glycation end-products and Porphyromonas gingivalis lipopolysaccharide on the expression of osteoblastic markers of rat bone marrow cells in culture Blackwell Munksgaard Journal of Periodontal Research 1600-0765 51 3 313 320 20160601 10.1111/jre.12310 26223811 2-s2.0-84938353798 mihachie/published_papers/28661799 Y. Hiroshima M. Bando Y. Inagaki C. Mihara M. Kataoka H. Murata Y. Shinohara T. Nagata J. Kido Resistin in gingival crevicular fluid and induction of resistin release by Porphyromonas gingivalis lipopolysaccharide in human neutrophils JOURNAL OF PERIODONTAL RESEARCH 0022-3484 47 5 554 562 20121000 10.1111/j.1600-0765.2011.01466.x mihachie/published_papers/15839556 Y. Hiroshima M. Bando Y. Inagaki C. Mihara M. Kataoka H. Murata Y. Shinohara T. Nagata J. Kido Resistin in gingival crevicular fluid and induction of resistin release by Porphyromonas gingivalis lipopolysaccharide in human neutrophils Journal of Periodontal Research 0022-3484 47 5 554 562 20121000 10.1111/j.1600-0765.2011.01466.x 22309231 2-s2.0-84865553635 mihachie/published_papers/15839555 Chie Mihara-Wada 美原(和田) 智恵徳永格 Hiroyuki Seto 瀬戸浩行 Eijiro Sakamoto 坂本英次郎 Yuka Hiroshima 廣島佑香 Jun-ichi Kido 木戸淳一 Toshihiko Nagata 永田俊彦 Topical injection of osteoprotegerin prevents alveolar bone loss in rat experimental periodontitis ラット実験的歯周炎におけるオステオプロテジェリンの局所投与による歯槽骨吸収抑制効果 Osteoprotegerin (OPG) is a decoy receptor for Receptor Activator of NF- Ligand (RANKL) and blocks differentiation and activation of osteoclasts. Clinical trials of OPG administration have been successfully performed for bone-destructive diseases such as osteoporosis, bone metastatic cancer, and rheumatoid arthritis. In the case of periodontitis, systemic administration of OPG has been reported to be effective for decreasing alveolar bone loss in rat models of experimental periodontitis. In this study, we investigated the effect of topical OPG injection every other day in a rat model of experimental periodontitis, which was established by a ligature placement at the upper 2 <sup>nd</sup>molar. Micro-CT analysis revealed that the distance from the cement-enamel junction to the alveolar bone crest (CEJ-ABC) was higher in the ligature group, and that the CEJ-ABC was significantly shorter in the ligature-OPG group than in the ligature-control group on days 5 and 14 after ligaturing. Analysis of tartrate-resistant acid phosphatase (TRAP) staining revealed that the number of TRAP-positive cells (osteoclasts) was significantly lower in the ligature-OPG group than in the ligature-control group, having decreased to one-third by day 5. These results demonstrate that topical injection of OPG could prevent alveolar bone loss in rat experimental periodontitis, suggesting that OPG may be useful for alveolar bone preservation in periodontitis. Nihon Shishubyo Gakkai Kaishi(J Jpn Soc Periodontol)54(2):167-174, 2012. オステオプロテジェリン(OPG)は，骨芽細胞に発現する NF-кВ受容体リガンド(receptor activator of NF-кВ ligand:RANKL)のおとり受容体であり，破骨細胞の分化誘導や活性化を抑制する作用がある．すでに骨粗鬆症や癌性骨転移やリウマチ様関節炎などに対する臨床試験で OPG の効果が得られている．歯周病に関しては，ラット実験的歯周炎に対して OPG の全身投与が有効であり歯槽骨吸収が減少することが報告されている．本研究では，ラット実験的歯周炎における OPG の局所投与効果を調べた．上顎第 2 臼歯をナイロン糸で結紮した後，5 日目および 14 日目の当該組織の変化をマイクロ CT および酒石酸抵抗性酸性フォスファターゼ(TRAP)染色の組織観察によって調べた．OPG は結紮後 1 日おきに局所注射した．マイクロ CT 画像でセメントエナメル境から歯槽骨頂までの距離を計測すると，結紮 5 日目および 14 日目とも結紮による明らかな歯槽骨吸収が認められ，結紮し OPG を投与した群(OPG 投与群)での歯槽骨吸収量は結紮対照群よりも有意に少なかった．また，結紮 5 日目において，歯槽骨頂部位での TRAP 陽性細胞数は，OPG 投与群では結紮対照群の1/3 であり，破骨細胞数は有意に少なかった．これらの結果から OPG の局所投与により歯槽骨吸収が抑制されることが示され，将来の歯槽骨吸収予防薬として OPG が有用である可能性が示唆された．日本歯周病学会会誌(日歯周誌)54(2):167-174, 2012 JAPANESE SOCIETY OF PERIODONTOLOGY Journal of the Japanese Association of Periodontology 日本歯周病学会会誌 0385-0110 54 2 167 174 20120500 10.2329/perio.54.167 mihachie/published_papers/28269661 K. Tokunaga H. Seto H. Ohba C. Mihara H. Hama M. Horibe S. Yoneda T. Nagata Topical and intermittent application of parathyroid hormone recovers alveolar bone loss in rat experimental periodontitis JOURNAL OF PERIODONTAL RESEARCH 0022-3484 46 6 655 662 20111200 10.1111/j.1600-0765.2011.01386.x mihachie/published_papers/15839557 K. Tokunaga H. Seto H. Ohba C. Mihara H. Hama M. Horibe S. Yoneda T. Nagata Topical and intermittent application of parathyroid hormone recovers alveolar bone loss in rat experimental periodontitis Journal of Periodontal Research 0022-3484 46 6 655 662 20111200 10.1111/j.1600-0765.2011.01386.x 21722135 2-s2.0-80054907899 mihachie/published_papers/39303526 Mihara Chie 美原智恵 Kido Jun-ichi 木戸淳一 Yoneda Satoshi 米田哲 Hiroshima Yuka 廣島佑香 Seto Hiroyuki 瀬戸浩行 Nagata Toshihiko 永田俊彦 A case report on gingival overgrowth in a patient with severe flare-out of upper incisors. 上顎前歯の著しいフレアアウトを伴った薬物性歯肉増殖症の一症例 JAPANESE SOCIETY OF PERIODONTOLOGY 特定非営利活動法人日本歯周病学会 Program and Abstracts of Annual Meeting of the Japanese Society of Periodontology 特定非営利活動法人日本歯周病学会学術大会プログラムおよび講演抄録集 2011 158 158 20110000 10.14833/amjsp.2011s.0.158.0 mihachie/published_papers/39306269 Bando Mika 板東美香 Hiroshima Yuka 廣島佑香 Inagaki Yuji 稲垣裕司 Kataoka Masatoshi 片岡正俊 Mihara Chie 美原智恵 Horibe Masumi 堀部ますみ Yoneda Satoshi 米田哲 Oishi Keiji 大石慶二 Ninomiya Masami 二宮雅美 Purevjav Javkhlan Kido Jun-ichi 木戸淳一 Nagata Toshihiko 永田俊彦 Analysis of biomarkers in gingival crevicular fluid of diabetes-associated periodontitis 糖尿病関連歯周炎における歯肉溝滲出液中バイオマーカーの分析 JAPANESE SOCIETY OF PERIODONTOLOGY 特定非営利活動法人日本歯周病学会 Program and Abstracts of Annual Meeting of the Japanese Society of Periodontology 特定非営利活動法人日本歯周病学会学術大会プログラムおよび講演抄録集 2009 71 71 20090000 10.14833/amjsp.2009f.0.71.0 mihachie/published_papers/39306240 Mihara Chie 美原智恵 Tokunaga Kaku 徳永格 Seto Hiroyuki 瀬戸浩行 Oba Hirofumi 大場博史 Hiroshima Yuka 廣島佑香 Kido Jun-ichi 木戸淳一 Nagata Toshihiko 永田俊彦 Effects of osteoprotegerin on inflammation and bone resorption in rat experimental periodontitis ラット実験的歯周炎におけるオステオプロテジェリンの骨吸収と炎症に及ぼす効果 JAPANESE SOCIETY OF PERIODONTOLOGY 特定非営利活動法人日本歯周病学会 Program and Abstracts of Annual Meeting of the Japanese Society of Periodontology 特定非営利活動法人日本歯周病学会学術大会プログラムおよび講演抄録集 2009 41 41 20090000 10.14833/amjsp.2009f.0.41.0 mihachie/published_papers/39305938 Mihara Chie 美原智恵 Seto Hiroyuki 瀬戸浩行 Kido Jun-ichi 木戸淳一 Nagata Toshihiko 永田俊彦 A case report of drug-induced gingival overgrowth treated by gingivectomy and removal of melanin pigmentation with laser 歯肉切除およびレーザーを用いて色素除去を行った薬物性歯肉増殖症患者の1症例 JAPANESE SOCIETY OF PERIODONTOLOGY 特定非営利活動法人日本歯周病学会 Program and Abstracts of Annual Meeting of the Japanese Society of Periodontology 特定非営利活動法人日本歯周病学会学術大会プログラムおよび講演抄録集 2008 101 101 20080000 10.14833/amjsp.2008s.0.101.0 mihachie/published_papers/15839558 N. Hayashi Noriko Hayashi J. Kido Jun-ichi Kido Suryono R. Kido Reiko Kido C. Wada Chie Mihara-Wada M. Kataoka Masatoshi Kataoka Y. Shinohara Yasuo Shinohara T. Nagata Toshihiko Nagata Regulation of calprotectin expression by interleukin-1 alpha and transforming growth factor-beta in human gingival keratinocytes Regulation of Calprotectin Expression by IL-1α and TGF-β in Human Gingival Keratinocytes JOURNAL OF PERIODONTAL RESEARCH Journal of Periodontal Research 0022-3484 42 1 1 7 20070200 10.1111/j.1600-0765.2005.00857.x 17214633 mihachie/published_papers/15839559 C Wada M Kataoka H Seto N Hayashi J Kido Y Shinohara T Nagata High-turnover osteoporosis is induced by cyclosporin A in rats JOURNAL OF BONE AND MINERAL METABOLISM 0914-8779 24 3 199 205 20060500 10.1007/s00774-005-0672-x 16622732 mihachie/published_papers/15839560 M Ogino J Kido M Bando N Hayashi C Wada T Nagata F Nishimura Y Soga S Takashiba T Kubota M Itagaki Y Shimada H Tai H Yoshie N Yamazaki Y Shinohara M Kataoka alpha 2 integrin+807 polymorphism in drug-induced gingival overgrowth JOURNAL OF DENTAL RESEARCH 0022-0345 84 12 1183 1186 20051200 10.1177/154405910508401217 16304451 mihachie/misc/12382443 Toshihiko Nagata Masami Ninomiya Chie Mihara-Wada Jun-ichi Kido Seiji Nishikawa Etiology of drug-induced gingival overgrowth Current Issues in Periodontics 1 8 20161000 mihachie/misc/39382216 MIHARA Chie 美原智恵 SETO Hiroyuki 瀬戸浩行 KIDO Jun-ichi 木戸淳一 NAGATA Toshihiko 永田俊彦 Effect of Cyclosporin A on Rat Bone Metabolism : Morphological Analysis of Alveolar Bone and Tibia サイクロスポリンAがラット骨代謝に及ぼす影響 : 歯槽骨と脛骨の形態学的分析日本歯科保存学雑誌 = THE JAPANESE JOURNAL OF CONSERVATIVE DENTISTRY 0387-2343 50 133 133 20071005 mihachie/misc/39381972 TOKUNAGA Kaku 徳永格 SETO Hiroyuki 瀬戸浩行 OHBA Hirofumi 大場博史 MIHARA Chie 美原智恵 NAGATA Toshihiko 永田俊彦 Feeding of low calcium diet increases the level of alveolar bone resorption in rat experimental periodontitis 低カルシウム飼育ラット実験的歯周炎における歯槽骨吸収量の増加日本歯科保存学雑誌 = THE JAPANESE JOURNAL OF CONSERVATIVE DENTISTRY 0387-2343 50 43 43 20071005 mihachie/presentations/3127729 Chie Mihara-Wada 美原(和田) 智恵 Jun-ichi Kido 木戸淳一 Masami Ninomiya 二宮雅美 Hiromichi Yumoto 湯本浩通 A case report of comprehensive treatment for an elderly patient of chronic periodontitis with drug-induced gingival overgrowth 薬物性歯肉増殖を伴う高齢の慢性歯周炎患者に対して包括的歯周治療を行った一症例 The Japanese Society of Periodontology 日本歯周病学会第61回秋季日本歯周病学会学術大会 20181027 mihachie/presentations/3127730 Chie Mihara-Wada 美原(和田) 智恵 Masami Ninomiya 二宮雅美 Jun-ichi Kido 木戸淳一 Toshihiko Nagata 永田俊彦降圧薬由来の歯肉増殖を伴う重度歯周炎患者に対する歯周治療の効果日本歯周病学会中国四国3大学・日本臨床歯周病学会中国四国支部合同研修会 20171112 mihachie/presentations/3127731 Masami Ninomiya 二宮雅美 Yuji Inagaki 稲垣裕司 Chie Mihara-Wada 美原(和田) 智恵 Mika Bandou 板東美香 Yukiko Nakajima 中島由紀子 Eijiro Sakamoto 坂本英次郎 Ikuta Takahisa 生田貴久 Nishikawa Yasufumi 西川泰史 Jung-Hwan Lew Kido Rie 木戸理恵 Takagi Ryousuke 高木亮輔 Nonaka Kouhei 野中康平 Koji Naruishi 成石浩司 Jun-ichi Kido 木戸淳一 Toshihiko Nagata 永田俊彦新規歯周組織再生剤「リグロス歯科用液キット」の有効性四国歯学会第51回例会 20170629 mihachie/presentations/3127732 Chie Mihara-Wada 美原(和田) 智恵 Koji Naruishi 成石浩司 Mika Bandou 板東美香西川泰史 Hwan Jung Lew Eijiro Sakamoto 坂本英次郎生田貴久河野薫 Yukari Kajiura 梶浦由加里橋本万里 Yukiko Nakajima 中島由紀子 Yuji Inagaki 稲垣裕司 Masami Ninomiya 二宮雅美 Jun-ichi Kido 木戸淳一 Toshihiko Nagata 永田俊彦アドバンスドOSCEを見据えた当科の模擬OSCEの概要 Shikoku Dental Research 四国歯学会雑誌 20170623 mihachie/presentations/3127733 Chie Mihara-Wada 美原(和田) 智恵 Jun-ichi Kido 木戸淳一 Toshihiko Nagata 永田俊彦 A case report of severe periodontitis with tooth movement induced by gingival overgrowth 歯肉増殖によって歯の移動を伴った重度歯周炎患者に対する歯周治療の効果 Journal of the Japanese Association of Periodontology 日本歯周病学会会誌 20161008 mihachie/presentations/3127734 Chie Mihara-Wada 美原(和田) 智恵ラット実験的歯周炎におけるオステオプロテジェリンの局所投与による歯槽骨吸収抑制効果薫風会セミナー 20140306 mihachie/presentations/3127725 Jun-ichi Kido Mika Bandou Yuji Inagaki Yuka Hiroshima Hiromi Murata Chie Mihara-Wada 梶浦由加里生田貴久篠原宏貴橋本万里 Yukiko Nakajima Yukiko Bandou Makoto Funaki Haruhiko Saito Toshihiko Nagata Diagnosis of diabetes-associated periodontitis using glycoalbumin and calprotectin in gingival crevicular fluid 10th Asian Pacific Society of Periodontology Meeting 20130903 mihachie/presentations/3127727 Toshihiko Nagata Jun-ichi Kido Mika Bandou Yuka Hiroshima Yuji Inagaki Hiromi Murata Chie Mihara-Wada Mika Bandou Makoto Funaki Diagnosis of diabetes-associated periodontitis using biomarkers in gingival crevicular fluid 91th General Session & Exhibition of the International Association for Dental Research. Seattle, USA 20130522 mihachie/presentations/3127726 E Sakamoto Chie Mihara-Wada T Ikuta Yuji Inagaki Jun-ichi Kido Toshihiko Nagata AGE and LPS inhibits osteoblastic differentiation in rat bone-marrow cells 91th General Session & Exhibition of the International Association for Dental Research, Settle, USA 20130522 mihachie/presentations/3127736 Eijiro Sakamoto 坂本英次郎 Chie Mihara-Wada 美原(和田) 智恵生田貴久 Yuji Inagaki 稲垣裕司 Jun-ichi Kido 木戸淳一 Toshihiko Nagata 永田俊彦ラット骨芽細胞の分化発現に及ぼす最終糖化産物とリポ多糖の影響第56回春季歯周病学会 20130500 mihachie/presentations/3127735 Jun-ichi Kido 木戸淳一 Mika Bandou 板東美香 Yukiko Bandou 坂東由記子 Yuji Inagaki 稲垣裕司 Yuka Hiroshima 廣島佑香梶浦由加里 Chie Mihara-Wada 美原(和田) 智恵 Hiromi Murata 村田裕美生田貴久篠原宏貴 Makoto Funaki 船木真理 Toshihiko Nagata 永田俊彦糖尿病関連歯周炎の診断マーカーとしての歯肉溝滲出液中グリコアルブミンとカルプロテクチンの有用性第56回日本糖尿病学会 20130500 mihachie/presentations/3127722 E Sakamoto Chie Mihara-Wada T Ikuta Yuji Inagaki Jun-ichi Kido Toshihiko Nagata Age and LPS inhibit osteoblastic differentiation in rat bone marrow cells. international Associatuin of dental Research 20130300 mihachie/presentations/3127728 Toshihiko Nagata Jun-ichi Kido Mika Bandou Yuka Hiroshima Yuji Inagaki Masami Ninomiya Chie Mihara-Wada Hiromi Murata Yukiko Bandou Makoto Funaki Diagnosis of diabetes-associated periodontitis by measuring biomarkers in gingival crevicular fluid The 9th International Diabetes Federation Western Pacific Region Congress/ The 4th AASD Scientific Meeting 20121124 mihachie/presentations/3127737 坂本英次郎 Chie Mihara-Wada 美原(和田) 智恵生田貴久 Yuji Inagaki 稲垣裕司 Jun-ichi Kido 木戸淳一 Toshihiko Nagata 永田俊彦ラット骨芽細胞の分化に及ぼす最終糖化産物とリポ多糖の影響第19回徳島骨代謝研究会 20121100 mihachie/presentations/3127738 坂本英次郎 Chie Mihara-Wada 美原(和田) 智恵生田貴久 Yuji Inagaki 稲垣裕司 Jun-ichi Kido 木戸淳一 Toshihiko Nagata 永田俊彦ラット骨芽細胞の分化発現に及ぼす最終糖化産物及びリポ多糖の影響第136回春季日本歯周病学会 20120600 mihachie/presentations/3127739 Jun-ichi Kido 木戸淳一 Yuji Inagaki 稲垣裕司 Mika Bandou 板東美香 Yuka Hiroshima 廣島佑香 Hiromi Murata 村田裕美 Chie Mihara-Wada 美原(和田) 智恵 Masumi Horibe 堀部ますみ Satoshi Yoneda 米田哲 Masami Ninomiya 二宮雅美 Keiji Oishi 大石慶二 Eijiro Sakamoto 坂本英次郎中島由紀子生田貴久浅原洋士 Toshihiko Nagata 永田俊彦バイオマーカーを用いた糖尿病関連歯周炎の診断研究 Journal of the Japanese Association for Dental Science 日本歯科医学会誌 20120300 mihachie/presentations/3127740 Chie Mihara-Wada 美原(和田) 智恵 Jun-ichi Kido 木戸淳一 Satoshi Yoneda 米田哲 Yuka Hiroshima 廣島佑香 Hiroyuki Seto 瀬戸浩行 Toshihiko Nagata 永田俊彦上顎前歯の著しいフレアアウトを伴った薬物性歯肉増殖症患者の一症例 Journal of the Japanese Association of Periodontology 日本歯周病学会会誌 20110500 mihachie/presentations/3127741 坂本英次郎 Chie Mihara-Wada 美原(和田) 智恵徳永格瀬戸浩行 Yuka Hiroshima 廣島佑香ラット実験的歯周炎におけるオステオプロテジェリンの影響第53回秋季日本歯周病学会高松 20100920 mihachie/presentations/3127744 Jun-ichi Kido 木戸淳一 Yuji Inagaki 稲垣裕司 Mika Bandou 板東美香 Yuka Hiroshima 廣島佑香 Masatoshi Kataoka 片岡正俊 Chie Mihara-Wada 美原(和田) 智恵 Masumi Horibe 堀部ますみ Satoshi Yoneda 米田哲坂本英次郎中島由紀子 Masami Ninomiya 二宮雅美 Keiji Oishi 大石慶二淺原洋士 Toshihiko Nagata 永田俊彦歯肉溝浸出液中の糖尿病関連歯周炎バイオマーカーの検索 Journal of the Japanese Association of Periodontology 日本歯周病学会会誌 20100514 mihachie/presentations/3127742 Yuji Inagaki 稲垣裕司 Jun-ichi Kido 木戸淳一 Mika Bandou 板東美香 Yuka Hiroshima 廣島佑香 Chie Mihara-Wada 美原(和田) 智恵糖尿病関連歯周炎における歯肉溝浸出液中のバイオマーカーの分析第53回日本糖尿病学会 20100500 mihachie/presentations/3127745 Yuji Inagaki 稲垣裕司 Jun-ichi Kido 木戸淳一 Mika Bandou 板東美香 Yuka Hiroshima 廣島佑香 Masatoshi Kataoka 片岡正俊 Chie Mihara-Wada 美原(和田) 智恵 Masumi Horibe 堀部ますみ Satoshi Yoneda 米田哲坂本英次郎中島由紀子 Masami Ninomiya 二宮雅美 Keiji Oishi 大石慶二淺原洋士 Toshihiko Nagata 永田俊彦糖尿病関連歯周炎における歯肉溝滲出液中のバイオマーカーの分析 Journal of the The Japan Diabetes Society 糖尿病 20100425 mihachie/presentations/3127746 Yuka Hiroshima 廣島佑香 Mika Bandou 板東美香 Jun-ichi Kido 木戸淳一 Yuji Inagaki 稲垣裕司 Chie Mihara-Wada 美原(和田) 智恵 Keiji Oishi 大石慶二 Masatoshi Kataoka 片岡正俊 Toshihiko Nagata 永田俊彦ヒト口腔上皮細胞における抗菌ペプチド遺伝子発現に及ぼす小柴胡湯の影響第131回日本歯科保存学会秋季学術大会 20091030 mihachie/presentations/3127748 Mika Bandou 板東美香 Yuka Hiroshima 廣島佑香 Yuji Inagaki 稲垣裕司 Masatoshi Kataoka 片岡正俊 Chie Mihara-Wada 美原(和田) 智恵 Masumi Horibe 堀部ますみ Satoshi Yoneda 米田哲 Keiji Oishi 大石慶二 Masami Ninomiya 二宮雅美 Javkhlan Purevjav Jun-ichi Kido 木戸淳一 Toshihiko Nagata 永田俊彦糖尿病関連歯周炎における歯肉溝浸出液中バイオマーカーの分析 Journal of the Japanese Association of Periodontology 日本歯周病学会会誌 20091011 mihachie/presentations/3127747 Chie Mihara-Wada 美原(和田) 智恵徳永格瀬戸浩行大場博史 Yuka Hiroshima 廣島佑香 Jun-ichi Kido 木戸淳一 Toshihiko Nagata 永田俊彦ラット実験的歯周炎におけるオステオプロテジェリンの骨吸収と炎症におよぼす効果第52回秋季日本歯周病学会学術大会 20091011 mihachie/presentations/3127749 Jun-ichi Kido 木戸淳一 Masatoshi Kataoka 片岡正俊 Mika Bandou 板東美香 Yuka Hiroshima 廣島佑香 Chie Mihara-Wada 美原(和田) 智恵 Toshihiko Nagata 永田俊彦マイクロチップ基板を用いたカルプロテクチンの測定‐歯周病診断法への応用の可能性について‐ 第52回春季日本歯周病学会学術大会 20090515 mihachie/presentations/3127724 Yuka Hiroshima Mika Bandou Takahiro Hasegawa Yuji Inagaki Chie Mihara-Wada Resistin release from neutrophils is induced by Porphyromonas gingivalis lipopolysaccharide. IADR (International Association of Dental Research) Barcelona, Spain, July 14-17, 2010 mihachie/presentations/3127723 E Sakamoto Chie Mihara-Wada K Tokunaga H Seto Yuka Hiroshima Topical application of osteoprotegerin inhibits alveolar bone loss in rat experimental periodontitis International Joint Symposium on Oral Science, Bali, Indonesia, Dec 17-19, 2010 Chie Mihara-Wada 美原(和田) 智恵 The Japanese Society of Periodontology 日本歯周病学会日本歯周病学会会誌賞ラット実験的歯周炎におけるオステオプロテジェリンの局所投与による歯槽骨吸収抑制効果 20130900 Chie Mihara-Wada 美原(和田) 智恵 Faculty of Dentistry 歯学部西野瑞穂歯科臨床医学奨励賞薬剤投与が歯周組織の代謝に及ぼす影響の解明 20120200 Chie Mihara-Wada 美原(和田) 智恵日本歯科保存学会日本歯科保存学会奨励賞 HIgh-turnover osteoporosis is induced by cyclosporin A in rats. 20080605