type: misc

label: url

en: プリオン病における神経変性のメカニズム

ja: プリオン病における神経変性のメカニズム

en: Clinical Neuroscience

ja: Clinical Neuroscience


en: 細胞内小器官の維持のための新たな分子機構

ja: 細胞内小器官の維持のための新たな分子機構

en: Experimental Medicine

ja: 実験医学


en: p97/p47-Mediated Biogenesis of Golgi and ER.

en: In mammalian cells, the Golgi apparatus and endoplasmic reticulum have typical structures during interphase: stacked cisternae located adjacent to the nucleus and a network of interconnected tubules throughout the cytoplasm, respectively. At mitosis their architectures disappear and are reassembled in daughter cells. p97, an AAA-ATPase, mediates membrane fusion and is required for reassembly of these organelles. In the p97-mediated membrane fusion, p47 was identified as an essential cofactor, through which p97 binds to a SNARE, syntaxin5. A second essential cofactor, VCIP135, was identified as a p97/p47/syntaxin5-interacting protein. Several lines of recent evidence suggest that ubiquitination may be implicated in the p97/p47 pathway; p47 binds to monoubiquitinated proteins and VCIP135 shows a deubiquitinating activity in vitro. For the cell-cycle regulation of the p97/p47 pathway, it has been reported that the localization and phosphorylation-dephosphorylation of p47 are crucial. In this review, we describe the components involved in the p97-mediated membrane fusion and discuss the regulation of the fusion pathway.

en: The Journal of Biochemistry

ja: The Journal of Biochemistry


en: [p97-mediated membrane fusion is required for Golgi and ER assembly].

ja: ゴルジ体・小胞体形成に必須なp97膜融合機構

en: Tanpakushitsu Kakusan Koso

ja: 蛋白質 核酸 酵素


en: 環境修復技術としてのコンポスト化

ja: 環境修復技術としてのコンポスト化

en: Seibutsu-kogaku Kaishi

ja: 生物工学会誌


en: バクテリオシン産生乳酸菌の培養工学

ja: バクテリオシン産生乳酸菌の培養工学


en: 生分解性プラスチックのコンポスト化技術

ja: 生分解性プラスチックのコンポスト化技術

en: 化学装置

ja: 化学装置


en: 乳酸菌によるバクテリオシンの培養工学

ja: 乳酸菌によるバクテリオシンの培養工学