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徳島大学 > 病院 > 診療科 > 小児·周産·女性科 > 小児科 > (researchmapへのインポート用CSV) [PDF解説]

研究活動

専門分野

医学 (Medicine)

研究テーマ

著書・論文

学術論文(審査論文):

1. Sultana Taskia Zaman, Hideki Arimochi, Satoshi Maruyama, Chieko Ishifune, Shin-ichi Tsukumo, Akiko Kitamura and Koji Yasutomo :
Notch Balances Th17 and Induced Regulatory T Cell Functions in Dendritic Cells by Regulating Aldh1a2 Expression.,
The Journal of Immunology, Vol.199, No.6, 1989-1997, 2017.
(DOI: 10.4049/jimmunol.1700645,   PubMed: 28779023)
2. Kazumi Okamura, Akiko Kitamura, Yoshiteru Sasaki, Hyun Doo Chung, Shoji Kagami, Kazuhiro Iwai and Koji Yasutomo :
Survival of mature T cells depends on signaling through HOIP.,
Scientific Reports, Vol.6, 36135, 2016.
(徳島大学機関リポジトリ: 112366,   DOI: 10.1038/srep36135,   PubMed: 27786304)
3. Hideki Arimochi, Yuki Sasaki, Akiko Kitamura and Koji Yasutomo :
Differentiation of preadipocytes and mature adipocytes requires PSMB8.,
Scientific Reports, Vol.6, 26791, 2016.
(徳島大学機関リポジトリ: 112317,   DOI: 10.1038/srep26791,   PubMed: 27225296,   Elsevier: Scopus)
4. Kurihara Takeshi, Hideki Arimochi, Bhuyan Ahmed Zaied, Chieko Ishifune, Tsumura Hideki, Ito Morihiro, Ito Yasuhiko, Akiko Kitamura, Yoichi Maekawa and Koji Yasutomo :
CD98 Heavy Chain Is a Potent Positive Regulator of CD4+ T Cell Proliferation and Interferon- Production In Vivo,
PLoS ONE, Vol.10, No.10, e0139692, 2015.
(DOI: 10.1371/journal.pone.0139692,   PubMed: 26444422)
5. Akiko Kitamura, Yuki Sasaki, Takaya Abe, Hirotsugu Kano and Koji Yasutomo :
An inherited mutation in NLRC4 causes autoinflammation in human and mice.,
The Journal of Experimental Medicine, Vol.211, No.12, 2385-2396, 2014.
(DOI: 10.1084/jem.20141091,   PubMed: 25385754,   Elsevier: Scopus)
6. Ahmed Zaied Bhuyan, Hideki Arimochi, Jun Nishida, Keiko Kataoka, Takeshi Kurihara, Chieko Ishifune, Hideki Tsumura, Morihiro Ito, Yasuhiko Ito, Akiko Kitamura and Koji Yasutomo :
CD98hc regulates the development of experimental colitis by controlling effector and regulatory CD4(+) T cells.,
Biochemical and Biophysical Research Communications, Vol.444, No.4, 628-633, 2014.
(DOI: 10.1016/j.bbrc.2014.01.144,   PubMed: 24491544,   Elsevier: Scopus)
7. Kohhei Nakajima, Yoichi Maekawa, Keiko Kataoka, Chieko Ishifune, Jun Nishida, Hideki Arimochi, Akiko Kitamura, Takayuki Yoshimoto, Shuhei Tomita, Shinji Nagahiro and Koji Yasutomo :
The ARNT-STAT3 axis regulates the differentiation of intestinal intraepithelial TCRαβ+CD8αα+cells.,
Nature Communications, Vol.4, 2112, 2013.
(DOI: 10.1038/ncomms3112,   PubMed: 23836150,   Elsevier: Scopus)
8. Gaojian Lian, Hideki Arimochi, Akiko Kitamura, Jun Nishida, Shigen Li, Kenji Kishihara, Yoichi Maekawa and Koji Yasutomo :
Manipulation of CD98 resolves type 1 diabetes in nonobese diabetic mice.,
The Journal of Immunology, Vol.188, No.5, 2227-2234, 2012.
(DOI: 10.4049/jimmunol.1102586,   PubMed: 22291182)
9. Shuichi Iwahashi, Yoichi Maekawa, Jun Nishida, Chieko Ishifune, Akiko Kitamura, Hideki Arimochi, Keiko Kataoka, Shigeru Chiba, Mitsuo Shimada and Koji Yasutomo :
Notch2 regulates the development of marginal zone B cells through Fos.,
Biochemical and Biophysical Research Communications, Vol.418, No.4, 701-707, 2012.
(DOI: 10.1016/j.bbrc.2012.01.082,   PubMed: 22293205,   Elsevier: Scopus)
10. Akiko Kitamura, Yoichi Maekawa, Hisanori Uehara, Keisuke Izumi, Izumi Kawachi, Masatoyo Nishizawa, Yasuko Toyoshima, Hitoshi Takahashi, M Daron Standley, Keiji Tanaka, Jun Hamazaki, Shigeo Murata, Koji Obara, Itaru Toyoshima and Koji Yasutomo :
A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans.,
The Journal of Clinical Investigation, Vol.121, No.10, 4150-4160, 2011.
(DOI: 10.1172/JCI58414,   PubMed: 21881205)
11. Maki Urushihara, Masanori Takamatsu, Maki Shimizu, Shuji Kondo, Yukiko Kinoshita, Kenichi Suga, Akiko Kitamura, Sato Matsuura, Masanori Yoshizumi, Toshiaki Tamaki, Hiroshi Kawachi and Shoji Kagami :
ERK5 activation enhances mesangial cell viability and collagen matrix accumulation in rat progressive glomerulonephritis.,
American Journal of Physiology, Renal Physiology, Vol.298, No.1, F167-76, 2010.
(DOI: 10.1152/ajprenal.00124.2009,   PubMed: 19846573)
12. Yoichi Maekawa, Yoshiaki Minato, Chieko Ishifune, Takeshi Kurihara, Akiko Kitamura, Hidefumi Kojima, Hideo Yagita, Mamiko Sakata-Yanagimoto, Toshiki Saito, Ichiro Taniuchi, Shigeru Chiba, Saburo Sone and Koji Yasutomo :
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.,
Nature Immunology, Vol.9, No.10, 1140-1147, 2008.
(DOI: 10.1038/ni.1649,   PubMed: 18724371)
13. Maki Urushihara, Shoji Kagami, Michinori Ito, Koji Yasutomo, Shuji Kondo, Akiko Kitamura, Akiyoshi Takahashi and Yasuhiro Kuroda :
Transforming growth factor-β in renal disease with glycogen storage disease I,
Pediatric Nephrology, Vol.19, No.6, 676-678, 2004.
(DOI: 10.1007/s00467-004-1456-6,   PubMed: 15064941)
14. Maki Urushihara, Shoji Kagami, Koji Yasutomo, Michinori Ito, Shuji Kondo, Akiko Kitamura, Dag Malm, Helle Klenow, Oiviind Nilssen and Yasuhiro Kuroda :
Sisters with α-mannosidosis and systemic lupus erythematosus,
European Journal of Pediatrics, Vol.163, No.4-5, 192-195, 2004.
(DOI: 10.1007/s00431-004-1404-2,   PubMed: 14760529)
15. Shuji Kondo, Shoji Kagami, Maki Shimizu, Akiko Kitamura, Maki Urushihara, Nobuo Satake, Keisuke Izumi and Yasuhiro Kuroda :
The role of mast cells in acute tubulo-interstitial nephritis with uveitis,
European Journal of Pediatrics, Vol.162, No.7-8, 496-499, 2003.
(DOI: 10.1007/s00431-003-1232-9,   PubMed: 12733071)
16. 近藤 秀治, 香美 祥二, 漆原 真樹, 北村 明子, 佐竹 宣法, 泉 啓介, 黒田 𣳾弘 :
肥満細胞浸潤を認めたぶどう膜炎を伴う間質性腎炎症候群の1女児例,
日本小児腎臓病学会雑誌, Vol.15, No.2, 7-10, 2002年.
(DOI: 10.3165/jjpn.15.89,   CiNii: 130000077833)
17. Akiko Kitamura, Shoji Kagami, Maki Urushihara, Syuji Kondo, Masanori Yoshizumi, Toshiaki Tamaki and Yasuhiro Kuroda :
Endothelin-1 is a potent stimulator of a1b1 integrin-mediated collagen matrix remodeling by rat mesangial cells.,
Biochemical and Biophysical Research Communications, Vol.299, 555-561, 2002.
18. Shoji Kagami, Shuzi Kondo, Maki Urushihara, Loster Klemens, Reutter Werner, Takahiko Saijo, Akiko Kitamura, Shoko Kobayashi and Yasuhiro Kuroda :
Overexpression of α1β1 integrin directly affects rat mesangial cell behavior,
Kidney International, Vol.58, No.3, 1088-1097, 2000.
(DOI: 10.1046/j.1523-1755.2000.00266.x,   PubMed: 10972673,   Elsevier: Scopus)
19. Shoji Kagami, Shuji Kondo, Loster Klemens, Werner Reutter, Maki Urushihara, Akiko Kitamura, Shoko Kobayashi and Yasuhiro Kuroda :
Collagen Type I Modulates the Platelet-Derived Growth Factor (PDGF) Regulation of the Growth and Expression of β1 Integrins by Rat Mesangial Cells,
Biochemical and Biophysical Research Communications, Vol.252, No.3, 728-732, 1998.
(DOI: 10.1006/bbrc.1998.9733,   PubMed: 9837774)

総説・解説:

1. 北村 明子, 安友 康二 :
稀少遺伝性疾患の原因遺伝子同定法の進歩,
臨床免疫·アレルギー科, Vol.66, No.2, 194-198, 2016年8月.
(CiNii: 40020941377)
2. Hideki Arimochi, Yuki Sasaki, Akiko Kitamura and Koji Yasutomo :
Dysfunctional immunoproteasomes in autoinflammatory diseases,
Inflammation and Regeneration, Vol.36, No.13, May 2016.
(徳島大学機関リポジトリ: 113982,   DOI: 10.1186/s41232-016-0011-8,   PubMed: 29259686)
3. 安友 康二, 北村 明子 :
生殖細胞系列変異 エクソーム解析による自己炎症疾患の遺伝的素因の解明 免疫プロテアソームの機能低下が自己炎症疾患を惹起する,
医学のあゆみ, Vol.245, No.5, 445-450, 2013年4月.
(CiNii: 40019642242)

国際会議:

1. Akiko Kitamura and Koji Yasutomo :
Candidate genetic variations in an autosomal-dominant selective immunodeficiency syndrome,
International Symposium on Genome Science ``Expanding Frontiers of Genome Science'', Tokyo, May 2012.
2. Akiko Kitamura and Koji Yasutomo :
Genome wide search for a candidate gene in idiopathic CD4+ T cell lymphocytopenia by combination of ANP-based homozygosity mapping and next generation sequencing,
60th Annual meeting of American society of human genetics, Hawaii, Nov. 2010.
3. Maki Urushihara, Masanori Takamatsu, Maki Shimizu, Shuji Kondo, Akiko Kitamura, Yukiko Kinoshita, Keisuke Ishizawa, Toshiaki Tamaki and Shoji Kagami :
The role of extracellular signal regulated kinase 5 in the accumulation of collagen matrix in rat mesangioproliferative glomerulonephritis,
40th ASN annual meeting, San Francisco, CA, Nov. 2007.

国内講演発表:

1. 北村 明子, 安友 康二 :
反復する発熱と脂肪萎縮を特徴とする症候群の原因遺伝子解明,
第114回 日本小児科学会学術集会, 2011年8月.
2. 水野 広一, 北村 明子, 佐々木 卓也 :
Rab8低分子量G蛋白質の新規標的蛋白質Rabring8の同定と機能解析,
第26回日本分子生物学会年会, 2003年12月.
3. 森本 慎也, 西村 範行, 北村 明子, 品原 和加子, 山本 恭代, 寺井 智也, 坂根 亜由子, 真鍋 進治, 田代 征記, 佐々木 卓也 :
Rabファミリー低分子量G蛋白質によるタイトジャンクション膜蛋白質の小胞輸送の制御機構,
第62回日本癌学会総会, 2003年9月.
4. 北村 明子, 水野 広一, 佐々木 卓也 :
Rab7低分子量G蛋白質の新規標的蛋白質Rabring7の同定と機能解析,
第25回日本分子生物学会年会, 2002年12月.
5. 水野 広一, 北村 明子, 佐々木 卓也 :
CytoTrapTM法を用いた新規Rab7標的蛋白質Rabring7の同定と機能解析,
第75回日本生化学会大会シンポジウム, 2002年10月.
6. 山本 恭代, 西村 範行, 森本 慎也, 北村 明子, 真鍋 進治, 佐々木 卓也 :
Rab3BとRab13低分子G蛋白質によるゴルジ体—細胞膜間小胞輸送の制御機構,
第75回日本生化学会大会, 2002年10月.

科学研究費補助金 (KAKEN Grants Database @ NII.ac.jp)

  • NLRC4インフラマソームの機能異常による自己炎症病態の分子基盤解明 (研究課題/領域番号: 16K10028 )
  • 免疫プロテアソームの機能異常による自己炎症病態の分子基盤解明 (研究課題/領域番号: 25461595 )
  • 連鎖解析とキャプチャーリシークエンスによる全身性エリテマトーデスの原因遺伝子同定 (研究課題/領域番号: 23791179 )
  • 全身性エリテマトーデスのゲノムワイド連鎖解析と疾患遺伝子の同定 (研究課題/領域番号: 21790991 )
  • 近交係数を指標とする小児遺伝性腎疾患の新しいマッピングの試み (研究課題/領域番号: 19790725 )
  • 研究者番号(10448318)による検索