shokoueta/published_papers/52753521 Sota Abe Tetsuro Katayama Akihiro Furube Atsushi Tabata Yasushi Yoshida Shoko Ueta Yukihiro Arakawa Keiji Minagawa Yasushi Imada Fumitoshi Yagishita Synthesis of naphthalene-fused imidazo[1,2-a]pyridinium salts showing green luminescence with high quantum yields and large Stokes shift ORGANIC & BIOMOLECULAR CHEMISTRY 1477-0539 23 18 4355 4359 20250507 10.1039/d5ob00447k shokoueta/published_papers/51015559 Fumitoshi Yagishita Tetsuro Katayama Yuta Kawamura Guran Watanabe Sota Abe Itsuki Ogawa Atsushi Tabata Yasushi Yoshida Hyuma Masu Shoko Ueta Yukihiro Arakawa Keiji Minagawa Akihiro Furube Yasushi Imada Blue Luminescent Boron Complexes Based on N,N‐Type Imidazo[1,5‐a]pyridine Ligand for Mitochondrial Imaging AbstractWe have synthesized two boron complexes based on N,N‐type bidentate imidazo[1,5‐a]pyridine ligands exhibiting blue emission with good quantum yields in solution. The transient absorption and theoretical studies of the boron complexes indicated the intramolecular charge transfer nature. In addition, one specific complex, 1 a was found to work as a mitochondrial imaging agent. Wiley Asian Journal of Organic Chemistry 2193-5815 null null 20240730 10.1002/ajoc.202400189 1871992116479763584 shokoueta/published_papers/51016527 Fumitoshi Yagishita Shoma Mukai Sota Abe Shoko Ueta Yasushi Yoshida Yukihiro Arakawa Keiji Minagawa Yasushi Imada Mechanochemical transformation of tetraaryl[3]cumulenes to benzofulvenes via electrophilic iodocyclization We demonstrate solvent-free mechanochemical iodocyclization of tetraaryl[3]cumulenes using N-iodosuccinimides as the first example of the molecular transformation of cumulenes based on mechanochemistry. Royal Society of Chemistry (RSC) RSC Mechanochemistry 2976-8683 1 318 321 20240101 10.1039/d4mr00022f 1873962441289563008 shokoueta/published_papers/51015418 上田昭子八木下史敏 Olex2を用いた特異な環状有機化合物の単結晶X線構造解析徳島大学技術支援部技術報告(Web) 2434-6411 6 null null 20230000 shokoueta/published_papers/51016891 , , , , Precipitant-Free Crystallization of Lysozyme and Glucose Isomerase by Drying Protein crystallization is usually conducted by using precipitants, although the ``salting-out'' phenomenon is still unclear and complex. Moreover, the addition of precipitants sometimes results in irreversible disordered precipitation of protein molecules. Although precipitant-free lysozyme crystals obtained by centrifugal concentration showed significant changes in three-dimensional structure compared to the structure of salted-out crystals, it was rather difficult to mount crystals from a viscous dense liquid phase after centrifugal concentration, and the quality of the crystals often deteriorated during the mounting process. Here we present novel precipitant-free crystallization methods, which were effective for lysozyme and glucose isomerase. Tetragonal lysozyme crystals were successfully crystallized in a glass capillary simply by drying highly concentrated lysozyme solution in the presence of 0.01 M hydrochloric acid without using any precipitants. Glucose isomerase dissolved in ultra-pure water was also successfully crystallized in hanging drops by drying highly concentrated solution under low-humidity conditions. Oscillation images of the obtained crystals were safely collected without handling; they clearly indicated the crystals had a tetragonal form for lysozyme and an orthorhombic form for glucose isomerase, and their lattice parameters are similar to those of previously reported crystals obtained by salting-out methods. Crystals 2073-4352 12 2 129 null 20220118 10.3390/cryst12020129 1050585658872617984 shokoueta/published_papers/51015623 鈴木良尚津下英明藤原汐里池光直人上田昭子坂井隆志 Protein Crystal Growth Simply by Concentration 濃縮のみによるタンパク質結晶化日本結晶成長学会誌(CD-ROM) 2188-7268 49 3 null null 20220000 shokoueta/published_papers/51015524 Keita Hoshi Masashi Yasuda Takumi Nakamura Yasushi Yoshida Shoko Ueta Keiji Minagawa Yasuhiko Kawamura Yasushi Imada Fumitoshi Yagishita Unexpected formation of poly-functionalized fulvenes by the reaction of a tetraaryl[5]cumulene with iodine. Longer cumulenes have come to draw considerable attention due to their unique properties and reactivities, leading to various hydrocarbons. In this manuscript, we describe the reaction of tetrakis(p-methoxyphenyl)[5]cumulene with iodine to afford poly-functionalized fulvenes via unexpected migration of a terminal aryl ring under ambient conditions. The obtained iodinated fulvenes were utilized in Suzuki-Miyaura cross-coupling reactions affording penta- and fully-arylated fulvenes successfully. Organic & biomolecular chemistry 19 35 7594 7597 20210915 10.1039/d1ob01270c 34524325 shokoueta/published_papers/51015557 Fumitoshi Yagishita Keita Hoshi Yasushi Yoshida Shoko Ueta Keiji Minagawa Yasushi Imada Yasuhiko Kawamura Cover Feature: Facile Construction of Benzofulvene Scaffold from Tetraaryl[3]cumulene Through Electrophilic Iodocyclization (Eur. J. Org. Chem. 2/2021) Wiley European Journal of Organic Chemistry 1099-0690 2021 162 162 20201221 10.1002/ejoc.202001600 1872272493020928768 shokoueta/published_papers/51015558 Fumitoshi Yagishita Keita Hoshi Yasushi Yoshida Shoko Ueta Keiji Minagawa Yasushi Imada Yasuhiko Kawamura Facile Construction of Benzofulvene Scaffold from Tetraaryl[3]cumulene Through Electrophilic Iodocyclization We found that the reaction of tetraaryl[3]cumulenes with N‐iodosuccinimide afforded the corresponding iodinated triarylbenzofulvenes with high yields under mild reaction conditions. Unsymmetrical tetraaryl[3]cumulenes underwent regioselective reactions to give a single isomer of benzofulvenes depending on the aryl substituents. The obtained iodinated benzofulvene was successfully used as aryl iodide for common cross‐coupling reactions, and the corresponding tetrasubstituted benzofulvenes was easily accessed via Suzuki–Miyaura and Sonogashira cross‐coupling reactions, respectively. Wiley European Journal of Organic Chemistry 1099-0690 2021 2 235 238 20201106 10.1002/ejoc.202001200 1360013172559780352 shokoueta/published_papers/51016920 上田昭子外輪健一郎導入教育としての物性測定装置作製の取組徳島大学技術支援部技術報告(Web) 2434-6411 2 null null 20190000 shokoueta/published_papers/51015556 Huijun Liu Shoko Ueta Fumitoshi Yagishita Masaki Nishiuchi Yasuhiko Kawamura ChemInform Abstract: One‐Pot Synthesis of Novel Polysubstituted 1,1′‐Phenylene‐bipyrrole via the Double [3 + 2] Cycloaddition Reaction. Abstract The novel polysubstituted 1,1′-phenylene-bipyrrole compounds were synthesized by the double [3+2] cycloaddition-extrusion reactions of N,N′-phenylene-bimunchnones and dimethyl acetylenedicarboxylate in dry toluene at 80 °C for 24 h. Bimunchnones were prepared successfully by cyclodehydration reactions of N,N′-biacyl-N,N′-(1,4-phenylene)-bis(2-arylglycine) with N,N′-diisopropylcarbodiimide in dry toluene at 0–5 °C for 1.5 h. The structures of the products were characterized on the basis of spectral data. Wiley ChemInform 1522-2667 46 null null 20150601 10.1002/chin.201537132 1870865117926764032 shokoueta/published_papers/51015525 Shoko Ueta Kazuo Hida Masaki Nishiuchi Yasuhiko Kawamura Regioisomeric allene dimer formation by the reaction of tetraarylbutatrienes with tetracyanoethene. The reaction of tetraarylbutatrienes (tetraaryl[3]cumulenes) with tetracyanoethene (TCNE), a strong electron-accepting molecule, at room temperature yielded novel four-membered ring compounds (head-to-tail unsymmetrically substituted diarylallene dimers) by [2 + 2] cycloaddition of the central C=C bond of the butatrienes. This reaction proceeded through a head-to-head symmetrically substituted diarylallene dimer intermediate. Unsymmetrical butatriene also formed a small amount of another head-to-tail dimer. Although the allene dimer is stable in nonpolar solvents, it converts to other bicyclic and tricyclic compounds in MeOH or CH3CN at room temperature. Organic & biomolecular chemistry 12 17 2784 91 20140507 10.1039/c3ob42574f 24668210 shokoueta/published_papers/51015436 SHIRAI Akihiro UETA Shouko MASEDA Hideaki KOURAI Hiroki OMASA Takeshi Action of Reactive Oxygen Species in the Antifungal Mechanism of Gemini-pyridinium Salts Against Yeast 酵母に対するジェミニピリジニウム塩の抗真菌機構における反応性酸化種の作用 Biocontrol Science 1342-4815 17 2 null null 20120000 shokoueta/misc/52591206 伊藤翼上田昭子南川慶二八木下史敏八木下史敏 Double-iodocyclization reaction of tetraaryl[4]cumulenes to construct spirocyclic Scaffolds テトラアリール[4]クムレンの二重ヨード環化反応によるスピロ環の構築ヨウ素 27 null null 20240000 shokoueta/misc/52591214 YAGISHITA Fumitoshi NII Chiho TEZUKA Yoshihiko TABATA Atsushi NAGAMUNE Hideaki UETA Shoko KAWAMURA Yasuhiko Synthesis and Evaluation of Photophysical Properties of Dimeric Imidazo[1,5-a]pyridinium Salts 二量体構造を有するイミダゾ[1,5-a]ピリジニウム塩の合成と発光特性評価日本化学会春季年会講演予稿集(CD-ROM) 98th null null 20180000 shokoueta/misc/52591231 鈴木良尚津下英明上田昭子細川晃平沈殿剤フリー高濃度リゾチーム溶液からの結晶成長結晶成長国内会議予稿集(CD-ROM) 2188-7268 43rd null null 20130000 shokoueta/presentations/51015414 吉川陸斗伊藤翼上田昭子南川慶二八木下史敏八木下史敏 Synthesis and reactivity of tetraaryl[4]cumulenes of tetraaryl[4]cumulenes テトラアリール[4]クムレンの合成と反応開拓日本化学会春季年会講演予稿集(Web) 20250000 shokoueta/presentations/51015417 阿部壮太上田昭子田端厚之南川慶二今田泰嗣八木下史敏八木下史敏 Synthesis of naphthalene-fused imidazo[1,2-a]pyridinium salts and photophysical properties ナフタレン縮環イミダゾ[1,2-a]ピリジニウム塩の合成と光物性評価日本化学会春季年会講演予稿集(Web) 20240000 shokoueta/presentations/51015416 小川樹上田昭子南川慶二八木下史敏八木下史敏 Synthesis of N,N-type imidazo[1,2-a]pyridine-BF2 complexes and photocytotoxicity N,N-型イミダゾ[1,2-a]ピリジン配位子のフッ化ホウ素錯体の合成と光細胞傷害性日本化学会春季年会講演予稿集(Web) 20240000 shokoueta/presentations/51015415 伊藤翼上田昭子南川慶二八木下史敏八木下史敏 Double-iodocyclization reaction of tetraaryl[4]cumulenes to construct spirocyclic Scaffolds テトラアリール[4]クムレンの二重ヨード環化反応によるスピロ環の構築ヨウ素 20240000 shokoueta/presentations/51015419 星恵太上田昭子片山哲郎片山哲郎古部昭広古部昭広南川慶二河村保彦今田泰嗣八木下史敏八木下史敏 Photodimerization of Tetraaryl[3]cumulenes and Crystallization-induced Emission of Dimers テトラアリール[3]クムレン類の光二量化とその二量体の結晶化誘起発光日本化学会春季年会講演予稿集(Web) 20210000 shokoueta/presentations/51015626 鈴木良尚藤原貴久津下英明本同宏成加藤有介植原悠太真板宣夫細川晃平上田昭子濃縮のみによるタンパク質結晶化と結晶構造解析日本物理学会講演概要集(CD-ROM) 20190000 shokoueta/presentations/51015624 鈴木良尚藤原貴久津下英明本同宏成加藤有介植原悠太真板宣夫細川晃平上田昭子 Protein Crystallization Achieved Simply by Concentration 濃縮するだけで実現するタンパク質結晶化結晶成長国内会議予稿集(CD-ROM) 20180000 shokoueta/presentations/51015509 YAGISHITA Fumitoshi NII Chiho TEZUKA Yoshihiko TABATA Atsushi NAGAMUNE Hideaki UETA Shoko KAWAMURA Yasuhiko Synthesis and Evaluation of Photophysical Properties of Dimeric Imidazo[1,5-a]pyridinium Salts 二量体構造を有するイミダゾ[1,5-a]ピリジニウム塩の合成と発光特性評価日本化学会春季年会講演予稿集(CD-ROM) 20180000 shokoueta/presentations/51015420 八木下史敏香西菜摘上田昭子手塚美彦西内優騎河村保彦イミダゾ[1,5-a]ピリジン二量体の酸・塩基性条件下での発光挙動日本化学会春季年会講演予稿集(CD-ROM) 20170000 shokoueta/presentations/51015510 YAGISHITA Fumitoshi KOZAI Natsumi UETA Shoko NISHIUCHI Masaki KAWAMURA Yasuhiko Synthesis of dimeric imidazo[1,5-a]pyridine and its photophysical properties イミダゾ[1,5-a]ピリジン二量体構造を母核とする含窒素複素環化合物群の合成と発光特性日本化学会春季年会講演予稿集(CD-ROM) 20160000 shokoueta/presentations/51016487 上田昭子外輪健一郎自動滴定装置の開発・改良を通じた化学分野におけるものづくり教育日本化学会講演予稿集 20150000 shokoueta/presentations/51015423 上田昭子西野聖八木下史敏西内優騎河村保彦光照射をトリガーとしたDNA切断活性分子の合成と機能日本化学会講演予稿集 20150000 shokoueta/presentations/51015422 橋爪裕一上田昭子八木下史敏西内優騎河村保彦非対称置換[4]ラジアレンの生成と光反応による固体発光性環状化合物への変換日本化学会講演予稿集 20150000 shokoueta/presentations/51015421 加藤年将上田昭子八木下史敏西内優騎河村保彦 o-ジエチニルベンゼンの光励起及び一電子移動による反応性日本化学会中国四国支部大会講演要旨集 20150000 shokoueta/presentations/51016494 西野聖上田昭子西内優騎河村保彦環状ニトロンの光誘起電子移動:酸素活性種の生成とDNA切断日本化学会講演予稿集 20140000 shokoueta/presentations/51016493 上田昭子加藤年将西内優騎河村保彦光照射をトリガーとしたDNA切断活性分子の合成と機能日本化学会講演予稿集 20140000 shokoueta/presentations/51016492 上田昭子外輪健一郎自動滴定装置の開発を通じた化学分野のものづくり教育日本化学会講演予稿集 20140000 shokoueta/presentations/51016879 西野聖上田昭子西内優騎河村保彦環状ニトロンの光誘起電子移動:酸素活性種の生成とDNA切断光化学討論会講演要旨集 20130000 shokoueta/presentations/51016496 上田昭子外輪健一郎粒度分布測定装置の開発を通じた化学分野のものづくり教育日本化学会講演予稿集 20130000 shokoueta/presentations/51016495 上田昭子西内優騎河村保彦テトラアリールブタトリエンとテトラシアノエテンの反応による特異な環状化合物の生成日本化学会講演予稿集 20130000 shokoueta/presentations/51016491 橋爪裕一上田昭子西内優騎河村保彦テトラアリール[4]及び[5]クムレンの熱反応及びテトラシアノエテンとの付加反応日本化学会中国四国支部大会講演要旨集 20130000 shokoueta/presentations/51016490 富山篤りう慧君上田昭子西内優騎河村保彦含硫黄メソイオン型化合物と[60]フラーレンとの付加環化反応日本化学会中国四国支部大会講演要旨集 20130000 shokoueta/presentations/51015625 鈴木良尚津下英明上田昭子細川晃平沈殿剤フリー高濃度リゾチーム溶液からの結晶成長結晶成長国内会議予稿集(CD-ROM) 20130000 shokoueta/presentations/51015560 Hida Kazuo 肥田和男 Aono Yuki 青野裕樹 Kurashina Masashi 倉科昌 Fujinaga Etsuko 藤永悦子 Ueta Shoko 上田昭子 Nishiuchi Masaki 西内優騎 Kawamura Yasuhiko 河村保彦 Generation of Unique Compounds Based on the Cycloaddition of Cumulenes クムレンの付加環化を基軸とした特異な化合物の生成 Cumulenes consist of cumulated double bonds and the sp carbons constitute the main molecular framework. Such electron-rich double bonds may react solely or with various reagents to afford a variety of products. The reactivity of cumulenes has been examined so far in view of the starting material for the preparations of exquisite molecules, a radialene, etc. No systematic survey has been done for the reactions of cumulenes. Here we wish to discuss rich chemistry of cumulenes such as formation of an extended radialene, generation of four-membered ring and heterocyclic compounds as well as the formation of the compound possessing a cross-conjugated carbon-carbon double bond. クムレンの有する累積二重結合は，構成するsp炭素原子がそれぞれ反応点となり得ることから多様な生成物が期待できる．しかし，ラジアレンの合成出発物としての研究が主なものであり，詳細な反応分析はなされていない．本研究では，クムレンの付加環化を基軸とした拡張ラジアレンの生成，複素環化合物や四員環化合物，さらに交叉共役二重結合化合物の生成と，多様性に富んだクムレンの化学変換を明らかにする． The Society of Physical Organic Chemistry, Japan 基礎有機化学会(基礎有機化学連合討論会) Abstracts of Symposium on Physical Organic Chemistry 基礎有機化学討論会要旨集(基礎有機化学連合討論会予稿集) 20110000