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The University of Tokushima > Graduate School of Medical Sciences > Medical Science > Course of Preventive Medicine >

Research Activity

Field of Study

Immunology

Subject of Study

T cell development and homeostasis (T cell)

Book / Paper

Book:

1.Kensuke Takada, A. K. Hogquist and C. S. Jameson :
Roles of Krüppel-like factors in lymphocytes.,
Springer-Verlag, 2009.

Academic Paper (Judged Full Paper):

1.Yousuke Takahama, Kensuke Takada, Shigeo Murata and Keiji Tanaka :
Beta5t-containing thymoproteasome: specific expression in thymic cortical epithelial cells and role in positive selection of CD8+ T cells.,
Current Opinion in Immunology, Vol.24, No.1, pp.92--98, 2012.
(DOI: 10.1016/j.coi.2012.01.006,   PubMed: 22285892,   Thomson Reuters: Web of Science®)
2.Kensuke Takada, Xiaodan Wang, T Geoffrey Hart, A Oludare Odumade, A Michael Weinreich, A Kristin Hogquist and C Stephen Jameson :
Kruppel-like factor 2 is required for trafficking but not quiescence in postactivated T cells.,
The Journal of Immunology, Vol.186, No.2, pp.775--783, 2010.
(DOI: 10.4049/jimmunol.1000094,   PubMed: 21160050,   Thomson Reuters: Web of Science®)
3.Kensuke Takada and Yousuke Takahama :
Another zinc finger in the pie of CD4-CD8 lineage choice,
Nature Immunology, Vol.11, No.5, pp.370--371, 2010.
(DOI: 10.1038/ni0510-370,   PubMed: 20404849,   Thomson Reuters: Web of Science®)
4.Kensuke Takada and Jameson Stephen :
Self-class I MHC molecules support survival of naïve CD8 T cells but depress their functional sensitivity through regulation of CD8 expression levels.,
The Journal of Experimental Medicine, Vol.206, No.10, pp.2253--2269, 2009.
(DOI: 10.1084/jem.20082553,   PubMed: 19752186,   Thomson Reuters: Web of Science®)
5.Michael A. Weinreich, Kensuke Takada, Cara Skon, Steven L. Reiner, Stephen C. Jameson and Kristin A. Hogquist :
KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors,
Immunity, Vol.31, No.1, pp.122--130, 2009.
(DOI: 10.1016/j.immuni.2009.05.011,   PubMed: 19592277,   Thomson Reuters: Web of Science®)
6.HH Chu, JJ Moon, Kensuke Takada, M Pepper, JA Molitor, TW Schacker, KA Hogquist, SC Jameson and MK Jenkins :
Positive selection optimizes the number and function of MHCII-restricted CD4+ T cell clones in the naive polyclonal repertoire,
Proceedings of the National Academy of Sciences of the United States of America, Vol.106, No.27, pp.11241--11245, 2009.
(DOI: 10.1073/pnas.0902015106,   PubMed: 19541603,   Thomson Reuters: Web of Science®)
7.A Konno, M Takiguchi, Kensuke Takada, T Usami, K Azumi, H Kubota, M Inaba, J Saegusa and Y Kon :
Identification of a quantitative trait locus regulating B cell-dominant infiltration into autoimmune sialitis lesions of the IQI mouse model of primary Sjögren's syndrome,
Immunogenetics, Vol.59, No.11, pp.853--859, 2007.
(DOI: 10.1007/s00251-007-0244-4,   PubMed: 17938903,   Thomson Reuters: Web of Science®)
8.Kensuke Takada, A Konno and M Inaba :
Autoimmunity against a tissue kallikrein in IQI/Jic Mice: a model for Sjogren's syndrome,
The Journal of Biological Chemistry, Vol.280, No.5, pp.3982--3988, 2005.
(DOI: 10.1074/jbc.M410157200,   PubMed: 15545270,   Thomson Reuters: Web of Science®)

Review, Commentary:

1.Kensuke Takada and Stephen C. Jameson :
Naive T cell homeostasis: from awareness of space to a sense of place.,
Nature Reviews. Immunology, Vol.9, No.12, pp.823--832, Dec. 2009.
(DOI: 10.1038/nri2657,   PubMed: 19935802,   Thomson Reuters: Web of Science®)

Proceeding of International Conference:

1.Kensuke Takada and Yousuke Takahama :
Functional abnormality of peripheral CD8 T cells in beta5t-deficient mice,
The 99th American Association of Immunologists Annual Meeting, May 2012.
2.Kensuke Takada and Yousuke Takahama :
Functional abnormality of peripheral CD8 T cells in β5t-deficient mice,
The 99th AAI Annual Meeting IMMUNOLOGY, Boston, May 2012.
3.Kensuke Takada and Yousuke Takahama :
Memory-like phenotype of CD8 T cells in 5t-deficient mice,
EUThyme-Rolduc Meeting, May 2011.
4.Kensuke Takada, GT Hart, OA Odumade, MA Weinreich and SC Jameson :
Kruppel-like factor 2 is dispensable for the quiescence of post-activated T cells,
International Congress of Immunology, Aug. 2010.
5.Kensuke Takada and SC Jameson :
Multiple roles of MHC class I in the maintenance of naïve CD8 T cells under non-lymphopenic conditions,
ThymOZ International Conference, Mar. 2010.

Proceeding of Domestic Conference:

1.Kensuke Takada and Yousuke Takahama :
β5t欠損マウスにおける末梢CD8T細胞の機能異常,
第21回 Kyoto T Cell Conference, Jul. 2012.
2.Kensuke Takada and Yousuke Takahama :
Analysis of peripheral CD8 T cells in 5t-deficient mice,
第40回日本免疫学会学術集会, Nov. 2011.
3.Kensuke Takada and Yousuke Takahama :
胸腺プロテアソーム非依存的に分化したCD8T細胞の機能解析,
第151回 日本獣医学会学術集会, Sep. 2011.
4.Kensuke Takada and Yousuke Takahama :
胸腺プロテアソーム構成因子β5t欠損マウスに認められるメモリー様CD8T細胞,
第21回 Kyoto T Cell Conference, Jun. 2011.
5.Kensuke Takada, Takeshi Nitta and Yousuke Takahama :
胸腺プロテアソーム構成因子β5t非依存的に分化したCD8T細胞の抗原特異性,
第20回Kyoto T Cell Conference, Jun. 2010.