Search:
Tokushima University > Graduate School of Biomedical Sciences > 歯学域 > Oral Science > Clinical Dentistry > Department of Conservative Dentistry >
Tokushima University > University Hospital > Clinical Division > Department of General Dentistry > Conservative Dentistry >
Tokushima University > Faculty of Dentistry > Course in Dentistry > Clinical Dentistry for Oral Health and Function > Conservative Dentistry >
(CSV files for researchmap) [PDF manual]

Research Activity

Field of Study

Subject of Study

Book / Paper

Academic Paper (Judged Full Paper):

1. Hitomi Kuramoto, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, Tadashi Nakanishi, Daisuke Takegawa, Ayako Washio, Chiaki Kitamura and Takashi Matsuo :
Caffeic acid phenethyl ester (CAPE) induces VEGF expression and production in rat odontoblastic cells,
BioMed Research International, Vol.Article ID 5390720, 2019.
(DOI: 10.1155/2019/5390720)
2. Hiromichi Yumoto, Katsuhiko Hirota, Kouji Hirao, Masami Ninomiya, Keiji Murakami, Hideki Fujii and Yoichiro Miyake :
The pathogenic factors from oral Streptococci for systemic diseases,
International Journal of Molecular Sciences, Vol.20, No.18, 2019.
(DOI: 10.3390/ijms20184571,   Elsevier: Scopus)
3. Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, Hitomi Kuramoto, 鷲尾 絢子, Tadashi Nakanishi, Daisuke Takegawa, 北村 知昭 and Takashi Matsuo :
ラット象牙芽細胞様細胞 (KN-3) におけるカテキンの抗炎症作用,
The Japanese Journal of Conservative Dentistry, Vol.60, No.5, 235-244, 2017.
4. Susilowati Heni, Keiji Murakami, Hiromichi Yumoto, Takashi Amoh, Kouji Hirao, Katsuhiko Hirota, Takashi Matsuo and Yoichiro Miyake :
Royal jelly inhibits Pseudomonas aeruginosa adherence and reduces excessive inflammatory responses in human epithelial cells,
BioMed Research International, Vol.2017, 3191752, 2017.
(Tokushima University Institutional Repository: 112385,   DOI: 10.1155/2017/3191752,   PubMed: 29075644,   Elsevier: Scopus)
5. Sekita Yasuko, Keiji Murakami, Hiromichi Yumoto, Kouji Hirao, Takashi Amoh, Natsumi Fujiwara, Katsuhiko Hirota, Hideki Fujii, Takashi Matsuo, Yoichiro Miyake and Yoshiki Kashiwada :
Antibiofilm and Anti-Inflammatory Activities of+ Houttuynia cordata Decoction for Oral Care,
Evidence-Based Complementary and Alternative Medicine : eCAM, Vol.2017, 2850947, 2017.
(Tokushima University Institutional Repository: 112956,   DOI: 10.1155/2017/2850947,   PubMed: 29234378,   Elsevier: Scopus)
6. Yuki Hosokawa, Kouji Hirao, Hiromichi Yumoto, Ayako Washio, Tadashi Nakanishi, Daisuke Takegawa, Chiaki Kitamura and Takashi Matsuo :
Functional roles of NOD1 in odontoblasts on dental pulp innate immunity,
BioMed Research International, Vol.2016, 9325436, 2016.
(Tokushima University Institutional Repository: 112386,   DOI: 10.1155/2016/9325436,   PubMed: 27747243,   Elsevier: Scopus)
7. Hiromichi Yumoto, Kouji Hirao, Toshihiko Tominaga, Naoki Bando, Kanako Takahashi and Takashi Matsuo :
Electromagnetic wave irradiation promotes osteoblastic cell proliferation and up-regulates growth factors via activation of the ERK1/2 and p38 MAPK pathways,
Cellular Physiology and Biochemistry, Vol.35, No.2, 601-615, 2015.
(DOI: 10.1159/000369722,   PubMed: 25612851,   Elsevier: Scopus)
8. Daisuke Takegawa, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
Modulatory roles of interferon-γ through indoleamine 2, 3-dioxygenase induction in innate immune response of dental pulp cells.,
Journal of Endodontics, Vol.40, No.9, 1382-1387, 2014.
(DOI: 10.1016/j.joen.2014.03.018,   PubMed: 25146019,   Elsevier: Scopus)
9. Hiromichi Yumoto, Katsuhiko Hirota, Kouji Hirao, Tsuyoshi Miyazaki, Nobuyuki Yamamoto, Koji Miyamoto, Keiji Murakami, Natsumi Fujiwara, Takashi Matsuo and Yoichiro Miyake :
Anti-inflammatory and protective effects of 2-methacryloyloxyethyl phosphorylcholine polymer on oral epithelial cells.,
Journal of Biomedical Materials Research. Part A, Vol.103, No.2, 555-563, 2014.
(DOI: 10.1002/jbm.a.35201,   PubMed: 24753309)
10. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami, Takashi Matsuo and Yoichiro Miyake :
Effect of extracellular DNA on pyocyanin production from Pseudomonas aeruginosa,
Bacterial Adherence & Biofilm, Vol.27, 45-47, 2014.
11. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami, Takashi Matsuo and Yoichiro Miyake :
Role of Extracellular DNA and DNA-binding protein in biofilm formation of Streptococcus intermeius,
Bacterial Adherence & Biofilm, Vol.26, 25-29, 2013.
12. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, D Liu, Kanako Takahashi, Keiji Murakami, Takashi Matsuo, R Shu and Yoichiro Miyake :
Effects of extracellular DNA and DNA-binding protein on the development of a Streptococcus intermedius biofilm.,
Journal of Applied Microbiology, Vol.115, No.1, 260-270, 2013.
(Tokushima University Institutional Repository: 106279,   DOI: 10.1111/jam.12202,   PubMed: 23551549)
13. Hiromichi Yumoto, Toshihiko Tominaga, Kouji Hirao, Tomoko Kimura, Kanako Takahashi, Takashi Sumitomo, Naoki Bando and Takashi Matsuo :
Bactericidal activity and oral pathogen inactivation by electromagnetic wave irradiation,
Journal of Applied Microbiology, Vol.113, No.1, 181-191, 2012.
(DOI: 10.1111/j.1365-2672.2012.05307.x,   PubMed: 22507081)
14. 坂東 直樹, 富永 敏彦, Hiromichi Yumoto, 住友 孝史, 平尾 早希, Kouji Hirao and Takashi Matsuo :
Application of electro-magnetic wave irradiation for endodontic treatment -EMAT (electro-magnetic apical treatment)-,
The Journal of Japan Endodontic Association, Vol.32, No.3, 184-200, 2011.
(CiNii: 10029697519)
15. Kouji Hirao, Hiromichi Yumoto, Tadashi Nakanishi, Kayo Mukai, Kanako Takahashi, Daisuke Takegawa and Takashi Matsuo :
Tea catechins reduce inflammatory reactions via mitogen-activated protein kinase pathways in toll-like receptor 2 ligand-stimulated dental pulp cells.,
Life Sciences, Vol.86, No.17-18, 654-660, 2010.
(DOI: 10.1016/j.lfs.2010.02.017,   PubMed: 20176036)
16. Tadashi Nakanishi, Kayo Mukai, Hiromichi Yumoto, Kouji Hirao, Yoshitaka Hosokawa and Takashi Matsuo :
Anti-inflammatory effect of catechin on cultured dental pulp cells affected by bacteria-derived factors,
European Journal of Oral Sciences, Vol.118, No.2, 145-150, 2010.
(DOI: 10.1111/j.1600-0722.2010.00714.x,   PubMed: 20487003)
17. Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi, Kayo Mukai, Tadashi Nakanishi and Takashi Matsuo :
Roles of TLR2, TLR4, NOD2, and NOD1 in pulp fibroblasts.,
Journal of Dental Research, Vol.88, No.8, 762-767, 2009.
(DOI: 10.1177/0022034509341779,   PubMed: 19734466)
18. Dali Liu, Hiromichi Yumoto, Katsuhiko Hirota, Keiji Murakami, Kanako Takahashi, Kouji Hirao, Takashi Matsuo, Kazuto Ohkura, Hideaki Nagamune and Yoichiro Miyake :
Histone-like DNA binding protein of Streptococcus intermedius induces the expression of pro-inflammatory cytokines in human monocytes via action of ERK1/2 and JNK pathways,
Cellular Microbiology, Vol.10, No.1, 262-276, 2008.
(DOI: 10.1111/j.1462-5822.2007.01040.x,   PubMed: 17883418)
19. Tomohiko Adachi, Tadashi Nakanishi, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Kayo Mukai, Hideaki Nakae and Takashi Matsuo :
Caries-related bacteria and cytokines induce CXCL10 in dental pulp.,
Journal of Dental Research, Vol.86, No.12, 1217-1222, 2007.
(DOI: 10.1177/154405910708601215,   PubMed: 18037659)

Academic Paper (Unrefereed Paper):

1. Takashi Matsuo, Tadashi Nakanishi, Hiromichi Yumoto, Kouji Hirao, Chihiro Shinohara and Toshihiko Tominaga :
Conception of Infected Root Canal Treatment,
Journal of Oral Health and Biosciences, Vol.28, No.2, 87-92, 2016.
(Tokushima University Institutional Repository: 109873,   CiNii: 120005823528)
2. Katsuhiko Hirota, Hiromichi Yumoto, Keiji Murakami, Kouji Hirao, Takashi Amoh and Yoichiro Miyake :
Streptococcus intermedius biofilm componentsの糖鎖結合能と炎症反応誘導能に関する解析,
Bacterial Adherence & Biofilm, Vol.29, 2016.

Academic Letter:

1. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami, Takashi Matsuo and Yoichiro Miyake :
Biological Roles of Extracellular DNA in Bacterial Infection,
Asean Plus and Tokushima Joint International Conference, Program and Proceeding Book, 47-48, 2012.

Review, Commentary:

1. Hiromichi Yumoto, Kouji Hirao, Yuki Hosokawa, Hitomi Kuramoto, Daisuke Takegawa, Tadashi Nakanishi and Takashi Matsuo :
The Roles of Odontoblasts in Dental Pulp Innate Immunity,
Japanese Dental Science Review, Vol.54, No.3, 105-117, Aug. 2018.
(Tokushima University Institutional Repository: 112960,   DOI: 10.1016/j.jdsr.2018.03.001,   PubMed: 30128058,   Elsevier: Scopus)
2. Takashi Matsuo, Kazumi Ozaki, Tadashi Nakanishi, Hiromichi Yumoto, Kanako Takahashi, Kouji Hirao and Daisuke Takegawa :
Pulp pathosis and its diagnosis,
日本歯内療法学会雑誌, Vol.34, No.2, 67-76, May 2013.
(CiNii: 10031183916)

Proceeding of International Conference:

1. Taketani Hideo, Masatake Akutagawa, Hiromichi Yumoto, Kouji Hirao, Takahiro Emoto, Tarao Hiroo, Tominaga Toshihiko, Toshitaka Ikehara and Yohsuke Kinouchi :
Experimental model simulation on electromagnetic wave therapy of apical periodontitis,
The Joint Annual Meeting of The Bioelectromagnetics Society and The European BioElectromagnetics Association (BioEM 2019) (Montpellier, France), Jun. 2019.
2. Shunsuke Yamaguchi, Masatake Akutagawa, Hiromichi Yumoto, Kouji Hirao, Takahiro Emoto, Hiroo Tarao, Toshihiko Tominaga, Toshitaka Ikehara and Yohsuke Kinouchi :
Effect of high frequency electric field on growth factor of cultured osteoblasts,
2018 The Joint Annual Meeting of the Bioelectromagnetics Society and the European BioElectromagnetics Association, Piran, Jun. 2018.
3. Hiroaki Shuu, Masatake Akutagawa, Hiromichi Yumoto, Takahiro Emoto, Toshihiko Tominaga, Kouji Hirao, Hiroo Tarao, Toshitaka Ikehara and Yohsuke Kinouchi :
Fundamental study on the mechanism of electromagnetic wave therapy of periapical periodontitis,
2017 The Joint Annual Meeting of The Bioelectromagnetics Society (BEMS) and the European BioElectromagnetics Association (EBEA) (Hangzhou, China), Jun. 2017.
4. Hiromichi Yumoto, Kouji Hirao, Yuki Hosokawa, Hitomi Kuramoto, Katsuhiko Hirota, Yoichiro Miyake and Takashi Matsuo :
Streptococcal histone-like DNA binding protein induces MINCLE expression on monocytes,
95th General Session & Exhibition of the International Association for Dental Research (San Francisco), Mar. 2017.
5. Yuki Hosokawa, Hiromichi Yumoto, Kouji Hirao, Hitomi Kuramoto, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
Anti-inflammatory effects of polyphenols on rat odontoblastic cells,
95th General Session & Exhibition of the International Association for Dental Research (San Francisco), Mar. 2017.
6. Daisuke Takegawa, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa and Takashi Matsuo :
Interferon-gamma modulates the innate immune response in odontoblast-like cells,
95th General session and exhibition of the IADR, Mar. 2017.
7. Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa and Takashi Matsuo :
Effect of interleukin-17A on CCL20 production from odontoblast-like cells,
95th General session and exhibition of the IADR, Mar. 2017.
8. Toshihiko Tominaga, Kazuki Takahira, Hiromichi Yumoto, Takashi Matsuo, Naoki Bando and Kouji Hirao :
EMAT (Electromagnetic Apical Treatment): Clinical Application of Pulsed Electric Current Energization for Root Canal Treatment,
2015 Annual Session of the American Association of Endodontists, Seattle (USA), May 2015.
9. Tadashi Nakanishi, Daisuke Takegawa, Hiromichi Yumoto, Kouji Hirao and Takashi Matsuo :
Interleukin-17 Regulates Inflammatory Mediator Expression in IL-1beta-stimulated Dental Pulp Cells,
93th General Session & Exhibition of the International Association for Dental Research, Boston (USA), Mar. 2015.
10. Kouji Hirao, Hiromichi Yumoto, Chihiro Shinohara, Hosokawa Yuki and Takashi Matsuo :
Functional roles of NOD1 in odontoblasts on pulp innate immunity,
The 62nd annual meeting of japanese association for dental research, 99, Dec. 2014.
11. Hiromichi Yumoto, Takashi Matsuo, Katsuhiko Hirota, Kouji Hirao, Miyazaki Tsuyoshi, Keiji Murakami, Natsumi Fujiwara and Yoichiro Miyake :
Anti-inflammatory and protective effects of 2-methacryloyloxyethyl-phosphorylcholine-polymer on oral epithelial cells,
92th General Session & Exhibition of the International Association for Dental Research (Cape Town, South Africa), Jun. 2014.
12. Hiromichi Yumoto, Katsuhiko Hirota, Kouji Hirao, Keiji Murakami, Yoichiro Miyake and Takashi Matsuo :
Pathogenic roles of Streptococcal histone-like protein in microbial infection,
The 15th Joint Scientific Meeting of JSCD-KACD (Gyeongju, Korea), Nov. 2013.
13. Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
Prostaglandin F2a Regulates Cytokine Expression in Dental Pulp Cells,
91th General Session & Exhibition of the IADR, Seattle, USA, Mar. 2013.
14. Daisuke Takegawa, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
Interferon-g modulates the innate immune response of dental pulp cells,
91th General Session & Exhibition of the IADR, Seattle, USA, Mar. 2013.
15. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami, Takashi Matsuo and Yoichiro Miyake :
Biological Roles of Extracellular DNA in Bacterial Infection,
Asean Plus and Tokushima Joint International Conference, Yogyakarta, Dec. 2012.
16. Hiromichi Yumoto, Toshihiko Tominaga, Kouji Hirao, Naoki Bando, Takashi Sumitomo, Kanako Takahashi and Takashi Matsuo :
Signaling Pathways and Gene Expression Activated by Electro-Magnetic-Wave in Osteoblastic-Cells,
90th General Session and Exhibition of the IADR, Iguazu Falls, Brazil, Jun. 2012.
17. Kouji Hirao, Hiromichi Yumoto, Katsuhiko Hirota, Dali Liu, Nur Asikin, Kanako Takahashi, Takashi Matsuo and Yoichiro Miyake :
Global Gene Analysis in Monocytes Stimulated with Streptococcal Histone-Like Protein,
90th General Session and Exhibition of the IADR, Iguazu Falls, Brazil, Jun. 2012.
18. Katsuhiko Hirota, Hiromichi Yumoto, Nur Asikin, Kouji Hirao, Kanako Takahashi, Liu Dali, Keiji Murakami, Takashi Matsuo and Yoichiro Miyake :
Gene Expression Profiling of Human Monocytic THP-1 Cells Stimulated With Extracellular Streptococcus intermedius Histone-Like DNA Binding Protein,
International Union of Microbiological Societies 2011 Congress, Sep. 2011.
19. Tadashi Nakanishi, Kouji Hirao, Takegawa Daisuke, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
Catechins suppress cyclooxygenase-2 expression in human dental pulp cells,
88th General Session and Exhibition of the IADR, Jul. 2010.
20. Takegawa Daisuke, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
Interferon-gamma enhances toll-like receptor ligand-induced cytokine production in pulpal cells,
88th General Session and Exhibition of the IADR, Jul. 2010.
21. Hiromichi Yumoto, T. TOMINAGA, Kouji Hirao, Tomoko Kimura and Takashi Matsuo :
Inactivation and Bactericidal Activity against Oral Bacteria of Electro-Magnetic Wave,
88th General Session and Exhibition of the IADR, Jul. 2010.
22. Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi, Kayo Mukai and Takashi Matsuo :
Expression and Functional Analyses of Pattern recognition Receptor (PRR) in Cultured Human Dental Pulp Cells,
The 1st international symposium and workshop "The Future Direction of Oral Sciences in the 21st century", Mar. 2007.
23. Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi, Kayo Mukai and Takashi Matsuo :
Expression and Functional Analyses of Pattern recognition Receptor (PRR) in Cultured Human Dental Pulp Cells,
The 8th Joint-Scientific Meeting between KACD & JSCD, Busan(Korea), Nov. 2006.

Proceeding of Domestic Conference:

1. Hitomi Kuramoto, Kouji Hirao, Yuki Hosokawa, Daisuke Takegawa, Hiromichi Yumoto and Tadashi Nakanishi :
ラット象牙芽細胞(KN-3)におけるVEGFの石灰化誘導作用,
日本歯科保存学会 2019年度秋季学術大会(第151回) (福岡), Nov. 2019.
2. Kouji Hirao, Hiromichi Yumoto, 富永 敏彦, 太良尾 浩生, Takahiro Emoto, Masatake Akutagawa, Toshitaka Ikehara and Yohsuke Kinouchi :
高周波電流を用いた歯周組織再生療法,
生体医工学シンポジウム2019 (徳島), Sep. 2019.
3. Daisuke Takegawa, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Yuki Hosokawa, 蔵本 瞳 and Takashi Matsuo :
Effects of interferon-γ on innate host responses in cultured odontoblast-like cells stimulated with NOD ligands,
第150回 日本歯科保存学会 2019年度 春季学術大会, Jun. 2019.
4. Hitomi Kuramoto, Hiromichi Yumoto, Kouji Hirao, Yuki Hosokawa and Takashi Matsuo :
Caffeic Acid Phenetyl Ester (CAPE)のラット象牙芽細胞(KN-3)におけるVEGF産生誘導機序の解析,
第40回日本歯内療法学会学術大会 (東京), Jun. 2019.
5. Kouji Hirao, Hiromichi Yumoto, Kunihiro Otsuka, Naozumi Ishimaru and Takashi Matsuo :
歯内由来病変と混同しやすい根尖病変様のエックス線透過像を有する症例,
第18回西日本歯内療法学会会研修会(2018年度), Sep. 2018.
6. 蔵本 瞳, Hiromichi Yumoto, Kouji Hirao, Yuki Hosokawa, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
Caffeic Acid Phenetyl Ester (CAPE)の象牙芽細胞と骨芽細胞におけるVEGF産生誘導機序の解析,
第148回日本歯科保存学会春季学術大会, Jun. 2018.
7. Kouji Hirao, Hitomi Kuramoto, Hiromichi Yumoto, Yuki Hosokawa and Takashi Matsuo :
プロポリス生理活性物質(CAPE; Caffeic Acid Phenetyl Ester)を用いた新規覆髄材の開発,
第17回西日本歯内療法学会研修会, Sep. 2017.
8. Kouji Hirao, Hiromichi Yumoto, 細川 由樹, 蔵本 瞳 and Takashi Matsuo :
ヒト歯髄組織ならびにラット象牙芽細胞(KN-3)におけるMincle発現と象牙芽細胞での機能解析,
第38回日本歯内療法学会学術大会 & 第14回日韓合同歯内療法学会学術大会, Jul. 2017.
9. 蔵本 瞳, Hiromichi Yumoto, Kouji Hirao, 細川 由樹, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
Caffeic Acid Phenethyl Ester (CAPE)のラット象牙芽細胞(KN-3)におけるVEGF産生に与える影響,
日本歯科保存学会2017年度春季学術大会(第146回), Jun. 2017.
10. Hiromichi Yumoto, Kouji Hirao, 細川 由樹, 蔵本 瞳 and Takashi Matsuo :
40年以上前に外傷を受けた根未完成歯の根尖部に硬組織形成の誘導を試みた症例,
第16回西日本歯内療法学会研修会, Sep. 2016.
11. 細川 由樹, Hiromichi Yumoto, Kouji Hirao and Takashi Matsuo :
ラット象牙芽細胞様細胞(KN-3)に対するポリフェノールの炎症抑制効果,
第37回日本歯内療法学会学術大会, Jul. 2016.
12. Kouji Hirao, Hiromichi Yumoto, 細川 由樹 and Takashi Matsuo :
Streptococci由来Histone-Like DNA binding protein (HLP)刺激の単球様細胞(THP-1)におけるMincle発現への影響,
日本歯科保存学会 2016年度春季学術大会(第144回), Jun. 2016.
13. Hiromichi Yumoto, Kouji Hirao, 細川 由樹 and Takashi Matsuo :
Streptococci由来Histone-Like DNA binding proteinの分泌機構と病原因子としての呼吸器感染症における役割,
日本歯科保存学会 2016年度春季学術大会(第144回), Jun. 2016.
14. Katsuhiko Hirota, Hiromichi Yumoto, Keiji Murakami, Kouji Hirao, Takashi Amoh and Yoichiro Miyake :
口腔常在菌Streptococcus intermediusが呼吸器疾患重症化に関与するメカニズム,
第89回日本細菌学会総会, Mar. 2016.
15. Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Hiromichi Yumoto, 細川 由樹 and Takashi Matsuo :
Interleukin-17がラット象牙芽細胞様細胞(KN-3)のCCL20産生に及ぼす影響,
日本歯科保存学会 2015年度秋季学術大会(第143回), Nov. 2015.
16. 細川 由樹, Hiromichi Yumoto, Kouji Hirao, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
象牙芽細胞が有するMincleを介した視細胞認識機構とその歯髄炎症反応における役割,
日本歯科保存学会 2015年度秋季学術大会(第143回), Nov. 2015.
17. Hiromichi Yumoto, Kouji Hirao, 富永 敏彦, Naoki Bandoh, Yuki Hosokawa and Takashi Matsuo :
外科的歯内療法の依頼を受けた根側病変に対して高周波・電磁波照射を応用した症例,
第15回日本歯内療法学会西日本支部会研修会, Sep. 2015.
18. 富永 敏彦, 高比良 一輝, 北池 光希, Naoki Bandoh, Hiromichi Yumoto, Kouji Hirao and Takashi Matsuo :
EMAT (Electro-Magnetic Apical Treatment)∼根尖性歯周炎への応用に関する検討,
第36回日本歯内療法学会学術大会 & 第13回日韓合同歯内療法学会学術大会, Jul. 2015.
19. Katsuhiko Hirota, Hiromichi Yumoto, Keiji Murakami, Kouji Hirao, Takashi Amoh and Yoichiro Miyake :
Streptococcus intermedius biofilm componentsの糖鎖結合能と炎症反応誘導に関する解析,
第29回日本バイオフィルム学術集会, Jul. 2015.
20. Kouji Hirao, Hiromichi Yumoto, 細川 由樹, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
ラット象牙芽細胞(KN-3)の自然免疫反応におけるシグナル伝達経路の解析,
日本歯科保存学会2015年度春季学術大会(第142回), Jun. 2015.
21. 細川 由樹, Hiromichi Yumoto, Kouji Hirao, Tadashi Nakanishi, Daisuke Takegawa and Takashi Matsuo :
ラット象牙芽細胞(KN-3)に対するカテキンとカフェイン酸の抗炎症作用,
日本歯科保存学会2015年度春季学術大会(第142回), Jun. 2015.
22. Takashi Matsuo, Tadashi Nakanishi, Hiromichi Yumoto, Chihiro Shinohara and Kouji Hirao :
感染根管治療の考え方,
四国歯学会(第46回例会), Mar. 2015.
23. Katsuhiko Hirota, Hiromichi Yumoto, Keiji Murakami, Kouji Hirao, 天羽 崇 and Yoichiro Miyake :
Streptococcus intermedius Histone-Like Proteinと細胞外ベシクルの特性,
第88回日本細菌学会総会, Mar. 2015.
24. Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Hiromichi Yumoto and Takashi Matsuo :
Interleukin-17がヒト歯髄線維芽細胞の炎症メディエーター発現に及ぼす影響,
日本歯科保存学会2014年度秋季学術大会(第141回), Oct. 2014.
25. Yuki Hosokawa, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi and Takashi Matsuo :
イグサ抽出液のオーラルヘルスケア製品への応用に関する研究,
日本歯科保存学会2014年度秋季学術大会(第141回), Oct. 2014.
26. Katsuhiko Hirota, Hiromichi Yumoto, Keiji Murakami, Kouji Hirao, 天羽 崇, Takashi Matsuo and Yoichiro Miyake :
Streptococcus intermedius Histone-Like DNA Binding Proteinの結合解析とExtracellular Vesicleとの関連,
第67回日本細菌学会中国・四国支部総会, Oct. 2014.
27. 太良尾 浩生, Hiromichi Yumoto, Kouji Hirao, 富永 敏彦, 坂東 直樹, 高比良 一輝, Takahiro Emoto, Masatake Akutagawa, Toshitaka Ikehara, Takashi Matsuo and Yohsuke Kinouchi :
電磁波照射による骨芽細胞培養培地内の電流密度分布とVEGF産生との関連,
第37回日本生体医工学会中国四国支部大会, Oct. 2014.
28. Hiromichi Yumoto, Kouji Hirao, 富永 敏彦, Naoki Bandoh, 高比良 一輝, 太良尾 浩生, Takahiro Emoto, Masatake Akutagawa, Toshitaka Ikehara, Takashi Matsuo and Yohsuke Kinouchi :
電磁波照射による骨芽細胞の活性化と成長因子の発現・産生誘導,
第37回生体医工学会中国四国支部大会, Oct. 2014.
29. Kouji Hirao, Hiromichi Yumoto, Tadashi Nakanishi, Chihiro Shinohara, Kanako Takahashi, Daisuke Takegawa, 細川 由樹 and Takashi Matsuo :
ラット象牙芽細胞様細胞(KN3)における細菌関連病原因子刺激に対する自然免疫反応の解析,
日本歯科保存学会2014年度春季学術大会(第140回), Jun. 2014.
30. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Keiji Murakami and Yoichiro Miyake :
Extracellular DNA influences pyocyanin production from Pseudomonas aeruginosa,
第87回日本細菌学会総会, Mar. 2014.
31. Katsuhiko Hirota, Hiromichi Yumoto, Keiji Murakami, Kouji Hirao and Yoichiro Miyake :
抗Si-HLP抗体のミトコンドリアATP synthase β subunitに対する交差反応性,
第87回日本細菌学会総会, Mar. 2014.
32. Kouji Hirao and Hiromichi Yumoto :
細菌関連病原因子によりラット象牙芽細胞の自然免疫反応の解析,
第87回日本細菌学会総会, Mar. 2014.
33. Hiromichi Yumoto, Kouji Hirao and Takashi Matsuo :
イグサ抽出液のう蝕および歯周病予防効果の評価,
第139回日本歯科保存学会秋季学術大会, Oct. 2013.
34. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami and Yoichiro Miyake :
Homologous and heterologous extracellular DNAs affect Pseudomonas aeruginosa to produce more pyocyanin without inducing bacterial growth,
第66回日本細菌学会中国・四国支部総会, Oct. 2013.
35. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami, Takashi Matsuo and Yoichiro Miyake :
Effect of extracellular DNA on pyocyanin production from Pseudomonas aeruginosa,
第27回Bacterial Agherence & Biofilm学術集会, Jul. 2013.
36. Hiromichi Yumoto, 富永 敏彦, 坂東 直樹, Kouji Hirao and Takashi Matsuo :
高周波・電磁波照射の歯内療法への応用ー基礎実験∼臨床症例ー,
第13回日本歯内療法学会西日本支部会研修会, Jul. 2013.
37. Katsuhiko Hirota, Hiromichi Yumoto, Keiji Murakami, Kouji Hirao, Kanako Takahashi, Takashi Matsuo and Yoichiro Miyake :
Streptococcus intermediusヒストン様タンパク質のPAMPsとしての解析,
第22回Lancefieldレンサ球菌研究会&第45回レンサ球菌感染症研究会, Jun. 2013.
38. 富永 敏彦, Hiromichi Yumoto, 坂東 直樹, Kouji Hirao, 平尾 早希, 加古 晋也, 前田 やよい, 山口 由美子, 高比良 一輝 and Takashi Matsuo :
Electro-Magnetic Apical Treatment ー嚢胞性疾患に対する対応ー,
第138回日本歯科保存学会春季学術大会, Jun. 2013.
39. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami and Yoichiro Miyake :
The role of extracellular DNA in Pseudomonas aeruginosa and Streptococcus intermedius infection,
第86回日本細菌学会総会, Mar. 2013.
40. Katsuhiko Hirota, Hiromichi Yumoto, Nur Asikin, Kouji Hirao, Keiji Murakami and Yoichiro Miyake :
Pathogenic roles of Streptococcus intermedius histone-like protein in microbial inflammation,
第86回日本細菌学会総会, Mar. 2013.
41. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami and Yoichiro Miyake :
Biological roles of extracellular DNA of Streptococcus intermeius,
第65回日本細菌学会中国・四国支部総会, Oct. 2012.
42. Hiromichi Yumoto, 富永 敏彦, Kouji Hirao and Takashi Matsuo :
電磁波照射による骨芽細胞の活性化とGrowth Factorの発現誘導,
第10回日本再生歯科医学会学術大会, Sep. 2012.
43. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami, Takashi Matsuo and Yoichiro Miyake :
Role of Extracellular DNA and DNA-binding protein in biofilm formation of Streptococcus intermeius,
第26回Bacterial Adherence & Biofilm学術集会, Jul. 2012.
44. Tadashi Nakanishi, Daisuke Takegawa, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
prostaglandin F2aは歯髄細胞における炎症性メディエーター発現を調節する,
第136回日本歯科保存学会春季学術大会, Jun. 2012.
45. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami, Takashi Matsuo and Yoichiro Miyake :
Roles of extracellular DNA and DNA-binding protein in cell aggregation, biofilm formation and antibiotic tolerance of Streptococcus intermedius,
第21回Lancefieldレンサ球菌研究会&第44回レンサ球菌感染症研究会合同開催, Jun. 2012.
46. Nur Asikin, Katsuhiko Hirota, Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Keiji Murakami and Yoichiro Miyake :
The Effect of Extracellular DNA on The Development of Streptococcus intermedius Biofilm,
第64回 日本細菌学会中国・四国支部総会, Oct. 2011.
47. Hiromichi Yumoto, 富永 敏彦, Kouji Hirao, Kanako Takahashi and Takashi Matsuo :
高周波・電磁波照射による骨芽細胞のGrowth Factorの発現・産生誘導,
第135回日本歯科保存学会秋季学術大会, Oct. 2011.
48. 武川 大輔, Tadashi Nakanishi, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
ヒト培養歯髄細胞の自然免疫応答に対するインターフェロンγの影響,
第134回日本歯科保存学会春季学術大会, Jun. 2011.
49. Hiromichi Yumoto, 富永 敏彦, 柴田 眞吾, 武川 大輔, Kanako Takahashi, Tomoko Kimura, Kouji Hirao and Takashi Matsuo :
高周波・電磁波照射を歯内療法に応用した症例,
第134回日本歯科保存学会春季学術大会, Jun. 2011.
50. 近藤 洋史, Tsuneko Ono, Katsuhiko Hirota, Keiji Murakami, Yoichiro Miyake, Hiromichi Yumoto, Kanako Takahashi, Kouji Hirao and Takashi Matsuo :
THP-1細胞のケモカイン産生に及ぼす口腔レンサ球菌ヒストン様DNA結合タンパク質の影響,
第34回徳島県医学検査学会, Dec. 2010.
51. Hiromichi Yumoto, Kanako Takahashi, Kouji Hirao and Takashi Matsuo :
Streptococcus intermedius由来histon様DNA結合タンパク質がTHP-1細胞のサイトカインバランスに及ぼす影響,
第133回日本歯科保存学会秋季学術大会, Oct. 2010.
52. Tadashi Nakanishi, 武川 大輔, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi and Takashi Matsuo :
ヒト歯髄細胞におけるサイトカイン発現に対するProstaglandin F2alpha の影響,
日本歯科保存学会2010年度秋季学術大会(第133回), Oct. 2010.
53. Kouji Hirao, Hiromichi Yumoto, Katsuhiko Hirota, Kanako Takahashi, Tomoko Kimura and Yoichiro Miyake :
Streptococcus intermedius由来histon様DNA結合タンパク質がヒト単球系細胞のサイトカイン・ケモカイン産生に及ぼす影響,
第63回日本細菌学会中国・四国支部総会, Oct. 2010.
54. Hiromichi Yumoto, Kouji Hirao, 木村 智子 and Kanako Takahashi :
口腔病原菌に対する高周波・電磁波照射の殺菌効果,
第83回日本細菌学会総会, Mar. 2010.
55. Kouji Hirao, Hiromichi Yumoto, Kayo Mukai, Kanako Takahashi, Tadashi Nakanishi and Takashi Matsuo :
カテキンは細菌やその構成成分に対する培養歯髄細胞の反応を調節する,
第127回日本歯科保存学会秋季学術大会, Nov. 2007.
56. Hiromichi Yumoto, Kouji Hirao, Kanako Takahashi, Kayo Mukai, Tadashi Nakanishi and Takashi Matsuo :
培養歯髄細胞におけるPattern Recognition Receptor (PRR)を介した接着分子の発現,
第127回日本歯科保存学会秋季学術大会, Nov. 2007.
57. Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi, Kayo Mukai and Takashi Matsuo :
う蝕関連細菌が歯髄細胞における自然免疫応答に及ぼす影響,
第125回日本歯科保存学会秋季学術大会, Nov. 2006.
58. Kouji Hirao, Kanako Takahashi and Hiromichi Yumoto :
培養歯髄細胞におけるPRR分子の解析,
第59回日本細菌学会中国・四国支部総会, Oct. 2006.
59. Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi, 足立 智彦, Kayo Mukai and Takashi Matsuo :
培養歯髄細胞におけるPattern Recognition Receptor (PRR)の発現と機能解析,
第124回日本歯科保存学会春季学術大会, May 2006.
60. 足立 智彦, Kouji Hirao, Hiromichi Yumoto, Kanako Takahashi, 向井 佳代, Tadashi Nakanishi, Hideaki Nakae and Takashi Matsuo :
歯髄組織および細菌刺激THP-1細胞におけるCXCR3 ligands(特にIP-10)の発現解析,
第123回秋季日本歯科保存会, Nov. 2005.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 細菌感染による死細胞を認識する自然免疫受容体Mincleの歯髄における役割の解明 (Project/Area Number: 18K09577 )
  • 初期の歯髄炎における象牙芽細胞の石灰化と生体防御機構の解明 (Project/Area Number: 17K11709 )
  • Development of novel dental pulp preservation and calcification therapies by analyzing epigenetics and post-transcriptional regulation mechanism (Project/Area Number: 15K11117 )
  • The analysis of odontoblastic mechanism via innate immune system (Project/Area Number: 15K11116 )
  • Functional analysis of Alarmin receptors in the pathogenesis of pulpitis (Project/Area Number: 25861803 )
  • The analyses of the immune system of odontoblast in the pathogenesis of pulpitis (Project/Area Number: 24592870 )
  • Development of new dental pulp protection therapy by anti-inflammatory effect of catechin (Project/Area Number: 23792177 )
  • Development of a new comprehensive treatment for dental caries based on minimum intervention dentistry (Project/Area Number: 23390435 )
  • Search by Researcher Number (00581399)