=== Generating (published_papers) ===
=== Generating (teaching_experience) ===
=== Generating (research_projects) ===
=== Generating (presentations) ===
==== begin registerFile(/WWW/pub2/data/ERD/person/244268/researchmap/published_papers.jsonl) ====
line:1, {"insert":{"user_id":"R000021451","type":"published_papers","id":"43134729"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/118939","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/37566681","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85166965831&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=402164","label":"url"}],"paper_title":{"en":"Republication of \"Mucous Cyst at the Interphalangeal Joint of the First Toe Caused by Contact Pressure With the Second Toe due to Hallux Valgus: A Case Report\".","ja":"Republication of \"Mucous Cyst at the Interphalangeal Joint of the First Toe Caused by Contact Pressure With the Second Toe due to Hallux Valgus: A Case Report\"."},"authors":{"en":[{"name":"Tonogai Ichiro"},{"name":"Yamasaki Yuhei"},{"name":"Nishisho Toshihiko"},{"name":"Sairyo Koichi"}],"ja":[{"name":"殿谷 一朗"},{"name":"山崎 悠平"},{"name":"西庄 俊彦"},{"name":"西良 浩一"}]},"description":{"en":"A 77-year-old woman presented with a mucous cyst on the lateral aspect of the interphalangeal joint of the first toe caused by contact pressure with the second toe from hallux valgus. She complained of discomfort and discharge from the left first toe for approximately 4 months. Physical examination showed the second toe pressing strongly against the first toe due to hallux valgus and discharge from the skin on the lateral aspect of the interphalangeal joint of the first toe. Magnetic resonance imaging showed a cystic lesion at the same level. The patient underwent a modified scarf osteotomy of the first metatarsal for hallux valgus to resolve the contact pressure between the toes-considered the cause of the mucous cyst-and resection of mucous cyst. Forefoot weight bearing was allowed 6 weeks after surgery. As of 1 year after surgery, she has had no recurrence of the cyst. The score on the Japanese Society for Surgery of the Foot hallux metatarsophalangeal-interphalangeal scale improved from 59/100 points to 92/100. This outcome suggests that hallux valgus correction should be considered when a mucous cyst is associated with contact pressure due to a hallux valgus deformity. To the best of our knowledge, there are no previous reports of a mucous cyst caused by contact pressure between the first toe and second toe due to hallux valgus.","ja":"A 77-year-old woman presented with a mucous cyst on the lateral aspect of the interphalangeal joint of the first toe caused by contact pressure with the second toe from hallux valgus. She complained of discomfort and discharge from the left first toe for approximately 4 months. Physical examination showed the second toe pressing strongly against the first toe due to hallux valgus and discharge from the skin on the lateral aspect of the interphalangeal joint of the first toe. Magnetic resonance imaging showed a cystic lesion at the same level. The patient underwent a modified scarf osteotomy of the first metatarsal for hallux valgus to resolve the contact pressure between the toes-considered the cause of the mucous cyst-and resection of mucous cyst. Forefoot weight bearing was allowed 6 weeks after surgery. As of 1 year after surgery, she has had no recurrence of the cyst. The score on the Japanese Society for Surgery of the Foot hallux metatarsophalangeal-interphalangeal scale improved from 59/100 points to 92/100. This outcome suggests that hallux valgus correction should be considered when a mucous cyst is associated with contact pressure due to a hallux valgus deformity. To the best of our knowledge, there are no previous reports of a mucous cyst caused by contact pressure between the first toe and second toe due to hallux valgus."},"publication_date":"2023-08-06","publication_name":{"en":"Foot & Ankle Orthopaedics","ja":"Foot & Ankle Orthopaedics"},"volume":"Vol.8","number":"No.3","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1177/24730114231192974"],"issn":["2473-0114"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:2, {"insert":{"user_id":"R000021451","type":"published_papers","id":"43134730"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/119255","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/37421768","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=402155","label":"url"}],"paper_title":{"en":"Atypical femoral fracture in a multiple myeloma patient undergoing treatment with denosumab: A case report and literature review.","ja":"Atypical femoral fracture in a multiple myeloma patient undergoing treatment with denosumab: A case report and literature review."},"authors":{"en":[{"name":"Ohmichi Yasuyuki"},{"name":"Toki Shun-ichi"},{"name":"Nishisho Toshihiko"},{"name":"Harada Takeshi"},{"name":"Sato Nori"},{"name":"Sairyo Koichi"}],"ja":[{"name":"大道 泰之"},{"name":"土岐 俊一"},{"name":"西庄 俊彦"},{"name":"Harada Takeshi"},{"name":"佐藤 紀"},{"name":"西良 浩一"}]},"description":{"en":"Atypical femoral fracture may occur in patients with multiple myeloma who receive denosumab, even for a short period. Attending physicians should be cognizant of the early symptoms and signs of this fracture.","ja":"A 71-year-old woman with multiple myeloma developed dull pain in her right thigh 8 months after restarting high-dose denosumab following its initial administration for 4 months and subsequent withdrawal for 2 years. Fourteen months later, complete atypical femoral fracture occurred. Osteosynthesis was achieved using an intramedullary nail and she was switched to oral bisphosphonate 7 months after cessation of denosumab. There was no exacerbation of the multiple myeloma. Bone union was achieved and she recovered to her pre-injury level of activities. The oncological outcome was alive with disease at 2 years after surgery."},"publication_date":"2023-07-03","publication_name":{"en":"International Journal of Surgery Case Reports","ja":"International Journal of Surgery Case Reports"},"volume":"Vol.108","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.ijscr.2023.108456"],"issn":["2210-2612"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:3, {"insert":{"user_id":"R000021451","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36722116","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=402151","label":"url"}],"paper_title":{"en":"Blue light induces apoptosis and autophagy by promoting ROS-mediated mitochondrial dysfunction in synovial sarcoma.","ja":"Blue light induces apoptosis and autophagy by promoting ROS-mediated mitochondrial dysfunction in synovial sarcoma."},"authors":{"en":[{"name":"Takeuchi Makoto"},{"name":"Nishisho Toshihiko"},{"name":"Toki Shun-ichi"},{"name":"Kawaguchi Shinji"},{"name":"Tamaki Shunsuke"},{"name":"Oya Takeshi"},{"name":"Uto Yoshihiro"},{"name":"Katagiri Toyomasa"},{"name":"Sairyo Koichi"}],"ja":[{"name":"竹内 誠"},{"name":"西庄 俊彦"},{"name":"土岐 俊一"},{"name":"川口 真司"},{"name":"玉置 俊輔"},{"name":"尾矢 剛志"},{"name":"宇都 義浩"},{"name":"片桐 豊雅"},{"name":"西良 浩一"}]},"description":{"en":"Taken together, our results revealed that BL induced apoptosis via the ROS-mitochondrial signaling pathway, and autophagy was activated in response to the production of ROS, which protected SS cells from apoptosis. Therefore, BL is a promising candidate for the development of an antitumor therapeutic strategy targeting SS.","ja":"Taken together, our results revealed that BL induced apoptosis via the ROS-mitochondrial signaling pathway, and autophagy was activated in response to the production of ROS, which protected SS cells from apoptosis. Therefore, BL is a promising candidate for the development of an antitumor therapeutic strategy targeting SS."},"publication_date":"2023-02-01","publication_name":{"en":"Cancer Medicine","ja":"Cancer Medicine"},"volume":"Vol.12","number":"No.8","starting_page":"9668","ending_page":"9683","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1002/cam4.5664"],"issn":["2045-7634"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:4, {"insert":{"user_id":"R000021451","type":"published_papers","id":"42384695"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=397010","label":"url"}],"paper_title":{"en":"四肢機能温存のために筋肉移植と関節包再建を行った症例の検討:最善の Orthoplastic Surgery を考える","ja":"四肢機能温存のために筋肉移植と関節包再建を行った症例の検討:最善の Orthoplastic Surgery を考える"},"authors":{"en":[{"name":"Abe Yoshiro"},{"name":"Mineda Kazuhide"},{"name":"Yamashita Yutaro"},{"name":"Nagasaka Shinji"},{"name":"Toki Shun-ichi"},{"name":"Nishisho Toshihiko"},{"name":"Sairyo Koichi"},{"name":"Hashimoto Ichiro"}],"ja":[{"name":"安倍 吉郎"},{"name":"峯田 一秀"},{"name":"山下 雄太郎"},{"name":"長坂 信司"},{"name":"土岐 俊一"},{"name":"西庄 俊彦"},{"name":"西良 浩一"},{"name":"橋本 一郎"}]},"publication_date":"2022-12-01","publication_name":{"en":"第49回日本マイクロサージャリー学会学術集会","ja":"第49回日本マイクロサージャリー学会学術集会"},"languages":["jpn"],"referee":true,"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:5, {"insert":{"user_id":"R000021451","type":"published_papers","id":"42260811"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/118921","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36482942","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=395938","label":"url"}],"paper_title":{"en":"Combination chemotherapy of doxorubicin and ifosfamide with proton beam therapy for myoepithelial carcinoma originating in the paraspinal region: A case report and literature review.","ja":"Combination chemotherapy of doxorubicin and ifosfamide with proton beam therapy for myoepithelial carcinoma originating in the paraspinal region: A case report and literature review."},"authors":{"en":[{"name":"Toki Shun-ichi"},{"name":"Nishisho Toshihiko"},{"name":"Miyagi Ryo"},{"name":"Bando Yoshimi"},{"name":"Sakaki Mika"},{"name":"Demizu Yusuke"},{"name":"Okimoto Tomoaki"},{"name":"Sairyo Koichi"}],"ja":[{"name":"土岐 俊一"},{"name":"西庄 俊彦"},{"name":"宮城 亮"},{"name":"坂東 良美"},{"name":"Sakaki Mika"},{"name":"Demizu Yusuke"},{"name":"Okimoto Tomoaki"},{"name":"西良 浩一"}]},"description":{"en":"Soft tissue myoepithelial carcinoma (MEC) is an extremely rare mesenchymal tumor that has a poor prognosis unless complete surgical resection is achieved. The present study reported a case of a 38-year-old woman with a tumor in the left paraspinal region at L2 to L3 with vertebral destruction. MEC was diagnosed based on molecular pathological examination of a biopsy specimen. Because curative surgery was expected to be difficult, a combination of chemotherapy with doxorubicin and ifosfamide and proton beam therapy as local therapy was performed, resulting in long-term survival for at least 7.8 years. To the best of our knowledge, this is the first case of soft tissue MEC for which classical cytotoxic chemotherapy and proton beam therapy were effective. Although surgical resection with negative margins is the mainstay of treatment for MEC, adequate doxorubicin-based systemic therapy and high-dose radiation therapy may be a feasible alternative in patients with unresectable or advanced MEC. Future studies on the relationship between molecular pathological features, including biomarkers, and the selection of therapeutic agents are warranted.","ja":"Soft tissue myoepithelial carcinoma (MEC) is an extremely rare mesenchymal tumor that has a poor prognosis unless complete surgical resection is achieved. The present study reported a case of a 38-year-old woman with a tumor in the left paraspinal region at L2 to L3 with vertebral destruction. MEC was diagnosed based on molecular pathological examination of a biopsy specimen. Because curative surgery was expected to be difficult, a combination of chemotherapy with doxorubicin and ifosfamide and proton beam therapy as local therapy was performed, resulting in long-term survival for at least 7.8 years. To the best of our knowledge, this is the first case of soft tissue MEC for which classical cytotoxic chemotherapy and proton beam therapy were effective. Although surgical resection with negative margins is the mainstay of treatment for MEC, adequate doxorubicin-based systemic therapy and high-dose radiation therapy may be a feasible alternative in patients with unresectable or advanced MEC. Future studies on the relationship between molecular pathological features, including biomarkers, and the selection of therapeutic agents are warranted."},"publication_date":"2022-11-03","publication_name":{"en":"Molecular and Clinical Oncology","ja":"Molecular and Clinical Oncology"},"volume":"Vol.17","number":"No.6","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3892/mco.2022.2596"],"issn":["2049-9469"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:6, {"insert":{"user_id":"R000021451","type":"published_papers","id":"41126293"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36201637","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=395937","label":"url"}],"paper_title":{"en":"ZFTA::RELA fusion in a distinct liposarcoma morphologically overlapping with chondroid lipoma.","ja":"ZFTA::RELA fusion in a distinct liposarcoma morphologically overlapping with chondroid lipoma."},"authors":{"en":[{"name":"Sumida Satoshi"},{"name":"Toki Shun-ichi"},{"name":"Mori Taisuke"},{"name":"Satomi Kaishi"},{"name":"Takao Shoichiro"},{"name":"Nobusawa Sumihito"},{"name":"Kakimoto Takumi"},{"name":"Nakagawa Shinya"},{"name":"Ryo Eijitsu"},{"name":"Matsushita Yuko"},{"name":"Ichimura Koichi"},{"name":"Nishisho Toshihiko"},{"name":"Bando Yoshimi"},{"name":"Yoshida Akihiko"}],"ja":[{"name":"Sumida Satoshi"},{"name":"土岐 俊一"},{"name":"Mori Taisuke"},{"name":"Satomi Kaishi"},{"name":"髙尾 正一郎"},{"name":"Nobusawa Sumihito"},{"name":"Kakimoto Takumi"},{"name":"Nakagawa Shinya"},{"name":"Ryo Eijitsu"},{"name":"Matsushita Yuko"},{"name":"Ichimura Koichi"},{"name":"西庄 俊彦"},{"name":"Bando Yoshimi"},{"name":"Yoshida Akihiko"}]},"description":{"en":"Chondroid lipoma is a rare benign adipose tumor characterized by a recurrent ZFTA::MRTFB fusion. Herein, we report an unusual liposarcoma that partly exhibited overlapping features with those of chondroid lipoma and harbored a ZFTA::RELA fusion. A 59-year-old man presented with a shoulder mass that had existed for approximately 8 years and with increasing pain due to a pelvic mass. The 5.8-cm resected shoulder tumor partly consisted of nests and strands of variably lipogenic epithelioid cells within a hyalinized or focally chondromyxoid stroma, indistinguishable from chondroid lipoma. The histological pattern gradually transitioned to highly cellular, stroma-poor, diffuse sheets of cells with greater nuclear atypia and mitotic activity. Vascular invasion and necrosis were present. The metastatic pelvic tumor revealed a similar histology. Despite multimodal treatment, the patient developed multiple bone metastases and succumbed to the disease 14 months after presentation. Targeted RNA sequencing identified an in-frame ZFTA (exon 3)::RELA (exon 2) fusion, which was confirmed by reverse transcription-polymerase chain reaction, Sanger sequencing, and break-apart fluorescent in situ hybridization assays. The tumor showed a different histology from that of ependymoma, no brain involvement, and no match with any sarcoma types or ZFTA::RELA-positive ependymomas according to DNA methylation analysis. p65 and L1CAM were diffusely expressed, and a CDKN2A/B deletion was present. This is the first report of an extra-central nervous system tumor with a ZFTA::RELA fusion. The tumor partly displayed an overlapping histology with that of chondroid lipoma, suggesting that it may represent a hitherto undescribed malignant chondroid lipoma with an alternative ZFTA fusion.","ja":"Chondroid lipoma is a rare benign adipose tumor characterized by a recurrent ZFTA::MRTFB fusion. Herein, we report an unusual liposarcoma that partly exhibited overlapping features with those of chondroid lipoma and harbored a ZFTA::RELA fusion. A 59-year-old man presented with a shoulder mass that had existed for approximately 8 years and with increasing pain due to a pelvic mass. The 5.8-cm resected shoulder tumor partly consisted of nests and strands of variably lipogenic epithelioid cells within a hyalinized or focally chondromyxoid stroma, indistinguishable from chondroid lipoma. The histological pattern gradually transitioned to highly cellular, stroma-poor, diffuse sheets of cells with greater nuclear atypia and mitotic activity. Vascular invasion and necrosis were present. The metastatic pelvic tumor revealed a similar histology. Despite multimodal treatment, the patient developed multiple bone metastases and succumbed to the disease 14 months after presentation. Targeted RNA sequencing identified an in-frame ZFTA (exon 3)::RELA (exon 2) fusion, which was confirmed by reverse transcription-polymerase chain reaction, Sanger sequencing, and break-apart fluorescent in situ hybridization assays. The tumor showed a different histology from that of ependymoma, no brain involvement, and no match with any sarcoma types or ZFTA::RELA-positive ependymomas according to DNA methylation analysis. p65 and L1CAM were diffusely expressed, and a CDKN2A/B deletion was present. This is the first report of an extra-central nervous system tumor with a ZFTA::RELA fusion. The tumor partly displayed an overlapping histology with that of chondroid lipoma, suggesting that it may represent a hitherto undescribed malignant chondroid lipoma with an alternative ZFTA fusion."},"publication_date":"2022-10-19","publication_name":{"en":"Genes, Chromosomes & Cancer","ja":"Genes, Chromosomes & Cancer"},"volume":"Vol.62","number":"No.2","starting_page":"101","ending_page":"106","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1002/gcc.23098"],"issn":["1098-2264"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:7, {"insert":{"user_id":"R000021451","type":"published_papers","id":"42260812"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36088237","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=395935","label":"url"}],"paper_title":{"en":"Dedifferentiated liposarcoma in the extremity and trunk wall: A multi-institutional study of 132 cases by the Japanese Musculoskeletal Oncology Group (JMOG).","ja":"Dedifferentiated liposarcoma in the extremity and trunk wall: A multi-institutional study of 132 cases by the Japanese Musculoskeletal Oncology Group (JMOG)."},"authors":{"en":[{"name":"Morii Takeshi"},{"name":"Anazawa Ukei"},{"name":"Sato Chiaki"},{"name":"Iwata Shintaro"},{"name":"Nakagawa Makoto"},{"name":"Endo Makoto"},{"name":"Nakamura Tomoki"},{"name":"Ikuta Kunihiro"},{"name":"Nishida Yoshihiro"},{"name":"Nakayama Robert"},{"name":"Udaka Toru"},{"name":"Kawamoto Teruya"},{"name":"Kito Munehisa"},{"name":"Sato Kenji"},{"name":"Imanishi Jungo"},{"name":"Akiyama Toru"},{"name":"Kobayashi Hiroshi"},{"name":"Nagano Akihito"},{"name":"Outani Hidetatsu"},{"name":"Toki Shunichi"},{"name":"Nishisho Toshihiko"},{"name":"Sasa Keita"},{"name":"Suehara Yoshiyuki"},{"name":"Kawano Hirotaka"},{"name":"Ueda Takafumi"},{"name":"Morioka Hideo"}],"ja":[{"name":"Morii Takeshi"},{"name":"Anazawa Ukei"},{"name":"Sato Chiaki"},{"name":"Iwata Shintaro"},{"name":"Nakagawa Makoto"},{"name":"Endo Makoto"},{"name":"Nakamura Tomoki"},{"name":"Ikuta Kunihiro"},{"name":"Nishida Yoshihiro"},{"name":"Nakayama Robert"},{"name":"Udaka Toru"},{"name":"Kawamoto Teruya"},{"name":"Kito Munehisa"},{"name":"Sato Kenji"},{"name":"Imanishi Jungo"},{"name":"Akiyama Toru"},{"name":"Kobayashi Hiroshi"},{"name":"Nagano Akihito"},{"name":"Outani Hidetatsu"},{"name":"土岐 俊一"},{"name":"西庄 俊彦"},{"name":"Sasa Keita"},{"name":"Suehara Yoshiyuki"},{"name":"Kawano Hirotaka"},{"name":"Ueda Takafumi"},{"name":"Morioka Hideo"}]},"description":{"en":"The typical clinical characteristics of dedifferentiated liposarcoma in the extremity and trunk wall were reconfirmed in the largest cohort ever. The evaluation of the dedifferentiated area in terms of grade, extension, and pathological margin, together with securing adequate surgical margins, was critical in the management of this entity.","ja":", French Federation of Cancer Centers Sarcoma Group grade III, and intralesional or marginal resection were independent risk factors for metastasis. A dedifferentiated area over 77 cm"},"publication_date":"2022-09-01","publication_name":{"en":"EJSO - European Journal of Surgical Oncology","ja":"EJSO - European Journal of Surgical Oncology"},"volume":"Vol.49","number":"No.2","starting_page":"353","ending_page":"361","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.ejso.2022.08.024"],"issn":["1532-2157"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:8, {"insert":{"user_id":"R000021451","type":"published_papers","id":"41369129"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36128054","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=393920","label":"url"}],"paper_title":{"en":"Preoperative Planning Using Three-dimensional Printing for Full-endoscopic Spine Surgery: A Technical Note.","ja":"Preoperative Planning Using Three-dimensional Printing for Full-endoscopic Spine Surgery: A Technical Note."},"authors":{"en":[{"name":"Okada Ryo"},{"name":"Sakai Toshinori"},{"name":"Nishisho Toshihiko"},{"name":"Nitta Akihiro"},{"name":"Takahara Shigeyuki"},{"name":"Oba Koichi"},{"name":"Sairyo Koichi"}],"ja":[{"name":"岡田 涼"},{"name":"酒井 紀典"},{"name":"西庄 俊彦"},{"name":"新田 晃弘"},{"name":"高原 茂之"},{"name":"大歯 浩一"},{"name":"西良 浩一"}]},"description":{"en":"Transforaminal full-endoscopic spine surgery (TF-FESS) is a novel minimally invasive spine surgery that requires only an 8-mm skin incision and causes minimal damage to the paravertebral muscles. To perform TF-FESS safely and efficiently, preoperative planning is quite important as the intervention requires anatomical understanding and high technical skills. Recently, three-dimensional (3D) printing has become a useful tool in various surgeries, and several studies have addressed its efficacy; however, there are no reports on the application of 3D printing to FESS. In this study, we present two cases of severe lumbar deformities for which preoperative 3D printing was useful. The 3D printing enabled the surgeons to visualize and plan the drilling of the superior articular process for a successful foraminoplasty at a low cost. The manufacturing equipment cost about USD 900 and is able to produce an actual-size model at a cost of less than USD 10 per patient. In conclusion, preoperative planning using 3D printing should be adopted to safely perform FESS.","ja":"Transforaminal full-endoscopic spine surgery (TF-FESS) is a novel minimally invasive spine surgery that requires only an 8-mm skin incision and causes minimal damage to the paravertebral muscles. To perform TF-FESS safely and efficiently, preoperative planning is quite important as the intervention requires anatomical understanding and high technical skills. Recently, three-dimensional (3D) printing has become a useful tool in various surgeries, and several studies have addressed its efficacy; however, there are no reports on the application of 3D printing to FESS. In this study, we present two cases of severe lumbar deformities for which preoperative 3D printing was useful. The 3D printing enabled the surgeons to visualize and plan the drilling of the superior articular process for a successful foraminoplasty at a low cost. The manufacturing equipment cost about USD 900 and is able to produce an actual-size model at a cost of less than USD 10 per patient. In conclusion, preoperative planning using 3D printing should be adopted to safely perform FESS."},"publication_date":"2022-08-20","publication_name":{"en":"NMC Case Report Journal","ja":"NMC Case Report Journal"},"volume":"Vol.9","starting_page":"249","ending_page":"253","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2176/jns-nmc.2022-0077"],"issn":["2188-4226"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:9, {"insert":{"user_id":"R000021451","type":"published_papers","id":"41369130"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/117758","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36244787","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390575263318498560/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85139885556&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=393918","label":"url"}],"paper_title":{"en":"Hemangioblastoma of the Cauda Equina : A Case Report and Review of the Literature.","ja":"Hemangioblastoma of the Cauda Equina : A Case Report and Review of the Literature."},"authors":{"en":[{"name":"Fujii Yugen"},{"name":"Nishisho Toshihiko"},{"name":"Tezuka Fumitake"},{"name":"Iwanami Akio"},{"name":"Yamashita Kazuta"},{"name":"Toki Shun-ichi"},{"name":"Morimoto Masatoshi"},{"name":"Sugiura Kosuke"},{"name":"Sakai Toshinori"},{"name":"Maeda Toru"},{"name":"Sairyo Koichi"}],"ja":[{"name":"藤井 悠玄"},{"name":"西庄 俊彦"},{"name":"手束 文威"},{"name":"Iwanami Akio"},{"name":"山下 一太"},{"name":"土岐 俊一"},{"name":"森本 雅俊"},{"name":"杉浦 宏祐"},{"name":"酒井 紀典"},{"name":"前田 徹"},{"name":"西良 浩一"}]},"description":{"en":"Introduction : Hemangioblastoma in the spine mainly occurs at the cervical and thoracic levels and is often associated with von Hippel-Lindau (VHL) syndrome. Here, we reported a quite rare case of spinal sporadic hemangioblastoma arising from the cauda equina. Case presentation : A 66-year-old woman presented with a 5-year history of low back and leg pain. Imaging revealed a hypervascular intradural extramedullary tumor in the lumbar region. Preoperative angiography helped to identify the feeding arteries and draining vein, and so facilitated subsequent tumor resection. The pain was dramatically improved but weakness of the left tibialis anterior and left extensor hallucis longus muscles persisted. Discussion : We reported a rare case of spinal hemangioblastoma arising from the cauda equina. Preoperative angiography may be useful for diagnosis and understanding of the anatomy of feeding veins. J. Med. Invest. 69 : 312-315, August, 2022.","ja":"Introduction : Hemangioblastoma in the spine mainly occurs at the cervical and thoracic levels and is often associated with von Hippel-Lindau (VHL) syndrome. Here, we reported a quite rare case of spinal sporadic hemangioblastoma arising from the cauda equina. Case presentation : A 66-year-old woman presented with a 5-year history of low back and leg pain. Imaging revealed a hypervascular intradural extramedullary tumor in the lumbar region. Preoperative angiography helped to identify the feeding arteries and draining vein, and so facilitated subsequent tumor resection. The pain was dramatically improved but weakness of the left tibialis anterior and left extensor hallucis longus muscles persisted. Discussion : We reported a rare case of spinal hemangioblastoma arising from the cauda equina. Preoperative angiography may be useful for diagnosis and understanding of the anatomy of feeding veins. J. Med. Invest. 69 : 312-315, August, 2022."},"publication_date":"2022","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.69","number":"No.3.4","starting_page":"312","ending_page":"315","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.69.312"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:10, {"insert":{"user_id":"R000021451","type":"published_papers","id":"39705156"},"force":{"see_also":[{"@id":"http://repo.lib.tokushima-u.ac.jp/115993","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/115993","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390288060504040448/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=390585","label":"url"}],"paper_title":{"en":"Clinical application of dynamic 18F-fluorodeoxyglucose positron-emission tomography / computed tomography in the differential diagnoses of musculoskeletal lesions","ja":"Clinical application of dynamic 18F-fluorodeoxyglucose positron-emission tomography / computed tomography in the differential diagnoses of musculoskeletal lesions"},"authors":{"en":[{"name":"Shinya Takayoshi"},{"name":"Yoichi Otomi"},{"name":"Nishisho Toshihiko"},{"name":"Beuthien-Baumann B"},{"name":"Irahara Saho"},{"name":"Kubo Michiko"},{"name":"Otsuka Hideki"},{"name":"Bando Yoshimi"},{"name":"Sairyo Koichi"},{"name":"Harada Masafumi"}],"ja":[{"name":"新家 崇義"},{"name":"Yoichi Otomi"},{"name":"西庄 俊彦"},{"name":"Beuthien-Baumann B"},{"name":"苛原 早保"},{"name":"久保 典子"},{"name":"大塚 秀樹"},{"name":"坂東 良美"},{"name":"西良 浩一"},{"name":"原田 雅史"}]},"description":{"en":"<p>We aimed to assess the differential diagnostic efficacy of dynamic F-18 fluorodeoxyglucose (FDG) positron emission tomography / computed tomography (PET / CT) and to evaluate the appropriate scan timings for diagnosis of musculoskeletal lesions (MSLs). Dynamic scans (5-15 [phase 1], 15-25 [phase 2], and 25-35 [phase 3] min after F-18 FDG injection) and dual-time-point scans (1 and 2 h after injection) were acquired for 23 MSLs [4 benign MSLs (BMSLs). 10 primary malignant musculoskeletal tumors (PMMSTs), and 9 metastatic musculoskeletal tumors (MMSTs)]. We compared the maximum standardized uptake values (SUVmax) and corresponding retention indices for dynamic (RI-SUVdyn) and dual-time-point (RI-SUVdual) scans and evaluated diagnostic efficacy using receiver operating characteristic (ROC) curve analyses. The SUVmax gradually decreased or was almost identical with minimal fluctuation in 3 BMSLs and 1 PMMST. SUVmax increased over time after phase 2 in 18 malignant MSLs (MMSLs). There were significant differences in SUVmax (for all time phases) and RI-SUV dual between BMSLs and MMSLs and between PMMSTs and MMSTs. In the ROC analyses, the areas under the curve for SUV in phases 2 and 3 were highest for differentiating BMSLs from MMSLs and PMMSTs from MMSTs, respectively. Dynamic F-18 FDG PET / CT is valuable for diagnosis of musculoskeletal lesions. J. Med. Invest. 68 : 96-104, February, 2021</p>","ja":"<p>We aimed to assess the differential diagnostic efficacy of dynamic F-18 fluorodeoxyglucose (FDG) positron emission tomography / computed tomography (PET / CT) and to evaluate the appropriate scan timings for diagnosis of musculoskeletal lesions (MSLs). Dynamic scans (5-15 [phase 1], 15-25 [phase 2], and 25-35 [phase 3] min after F-18 FDG injection) and dual-time-point scans (1 and 2 h after injection) were acquired for 23 MSLs [4 benign MSLs (BMSLs). 10 primary malignant musculoskeletal tumors (PMMSTs), and 9 metastatic musculoskeletal tumors (MMSTs)]. We compared the maximum standardized uptake values (SUVmax) and corresponding retention indices for dynamic (RI-SUVdyn) and dual-time-point (RI-SUVdual) scans and evaluated diagnostic efficacy using receiver operating characteristic (ROC) curve analyses. The SUVmax gradually decreased or was almost identical with minimal fluctuation in 3 BMSLs and 1 PMMST. SUVmax increased over time after phase 2 in 18 malignant MSLs (MMSLs). There were significant differences in SUVmax (for all time phases) and RI-SUV dual between BMSLs and MMSLs and between PMMSTs and MMSTs. In the ROC analyses, the areas under the curve for SUV in phases 2 and 3 were highest for differentiating BMSLs from MMSLs and PMMSTs from MMSTs, respectively. Dynamic F-18 FDG PET / CT is valuable for diagnosis of musculoskeletal lesions. J. Med. Invest. 68 : 96-104, February, 2021</p>"},"publication_date":"2021-02","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.68","number":"No.1. 2","starting_page":"96","ending_page":"104","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.68.96"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:11, {"insert":{"user_id":"R000021451","type":"published_papers","id":"33268804"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116522","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/34191157","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85100671212&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=378077","label":"url"}],"paper_title":{"en":"Preliminary clinical assessment of dynamic carbon-11 methionine positron-emission tomography/computed tomography for the diagnosis of the pathologies in patients with musculoskeletal lesions: a prospective study.","ja":"Preliminary clinical assessment of dynamic carbon-11 methionine positron-emission tomography/computed tomography for the diagnosis of the pathologies in patients with musculoskeletal lesions: a prospective study."},"authors":{"en":[{"name":"Shinya Takayoshi"},{"name":"Otomi Youichi"},{"name":"Nishisho Toshihiko"},{"name":"Beuthien-Baumann Bettina"},{"name":"Kubo Michiko"},{"name":"Otsuka Hideki"},{"name":"Bando Yoshimi"},{"name":"Yanagawa Hiroaki"},{"name":"Sairyo Koichi"},{"name":"Harada Masafumi"}],"ja":[{"name":"新家 崇義"},{"name":"音見 暢一"},{"name":"西庄 俊彦"},{"name":"Beuthien-Baumann Bettina"},{"name":"久保 典子"},{"name":"大塚 秀樹"},{"name":"坂東 良美"},{"name":"楊河 宏章"},{"name":"西良 浩一"},{"name":"原田 雅史"}]},"description":{"en":"Dynamic C-11 MET PET scans have the potential to be good predictors of discriminating MSLs in patients with primary unknown MSLs in clinical practice.","ja":"Dynamic C-11 MET PET scans have the potential to be good predictors of discriminating MSLs in patients with primary unknown MSLs in clinical practice."},"publication_date":"2020-08-26","publication_name":{"en":"European Journal of Hybrid Imaging","ja":"European Journal of Hybrid Imaging"},"volume":"Vol.26","number":"No.4","starting_page":"15","ending_page":"15","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1186/s41824-020-00083-x"],"issn":["2510-3636"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:12, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451072"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/114753","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/32378619","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=373703","label":"url"}],"paper_title":{"en":"Distribution of the Spinal Arteries in Adult Patients with Lumbar Spondylolysis.","ja":"Distribution of the Spinal Arteries in Adult Patients with Lumbar Spondylolysis."},"authors":{"en":[{"name":"Tezuka Fumitake"},{"name":"Sakai Toshinori"},{"name":"Nishisho Toshihiko"},{"name":"Sugiura Kosuke"},{"name":"Ishihama Yoshihiro"},{"name":"Manabe Hiroaki"},{"name":"Yamashita Kazuta"},{"name":"Takata Yoichiro"},{"name":"Maeda Toru"},{"name":"Sairyo Koichi"}],"ja":[{"name":"手束 文威"},{"name":"酒井 紀典"},{"name":"西庄 俊彦"},{"name":"杉浦 宏祐"},{"name":"石濱 嘉紘"},{"name":"眞鍋 裕昭"},{"name":"山下 一太"},{"name":"髙田 洋一郎"},{"name":"前田 徹"},{"name":"西良 浩一"}]},"description":{"en":"INTRODUCTION : The pathology of lumbar spondylolysis is generally thought to begin with a stress fracture in adolescence. Stress fractures of the lower extremities occur in watershed areas with a poor vascular supply because of an inability to respond to stress and heal. This pathology has not been well researched in the lumbar spine. The aim of this study was to evaluate the distribution of the spinal arteries in patients with lumbar spondylolysis. METHODS : The extraosseous distribution of the arteries around the pars interarticularis was retrospectively investigated in 14 patients with colon cancer who underwent abdominal contrast-enhanced computed tomography (CE-CT) as part of a preoperative assessment at our hospital and were found to have spondylolysis at L5. RESULTS : All patients were found to have terminal-stage spondylolysis at L5 (1 unilateral, 13 bilateral). L5 segmental artery was absent in all cases. However, separate spinal arteries supplying the pars interarticularis at L5 were found above and below the transverse process at this level. CONCLUSION : All the patients had two separate arteries originating from the cranial and caudal sides that distributed to the superior and inferior articular processes, suggesting that the pars interarticularis is a posterior element containing a vascular watershed area. J. Med. Invest. 67 : 62-66, February, 2020.","ja":"INTRODUCTION : The pathology of lumbar spondylolysis is generally thought to begin with a stress fracture in adolescence. Stress fractures of the lower extremities occur in watershed areas with a poor vascular supply because of an inability to respond to stress and heal. This pathology has not been well researched in the lumbar spine. The aim of this study was to evaluate the distribution of the spinal arteries in patients with lumbar spondylolysis. METHODS : The extraosseous distribution of the arteries around the pars interarticularis was retrospectively investigated in 14 patients with colon cancer who underwent abdominal contrast-enhanced computed tomography (CE-CT) as part of a preoperative assessment at our hospital and were found to have spondylolysis at L5. RESULTS : All patients were found to have terminal-stage spondylolysis at L5 (1 unilateral, 13 bilateral). L5 segmental artery was absent in all cases. However, separate spinal arteries supplying the pars interarticularis at L5 were found above and below the transverse process at this level. CONCLUSION : All the patients had two separate arteries originating from the cranial and caudal sides that distributed to the superior and inferior articular processes, suggesting that the pars interarticularis is a posterior element containing a vascular watershed area. J. Med. Invest. 67 : 62-66, February, 2020."},"publication_date":"2020-02","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.67","number":"No.1.2","starting_page":"62","ending_page":"66","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.67.62"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:13, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451073"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/31938676","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=363345","label":"url"}],"paper_title":{"en":"Intracanalicular Osteochondroma in the Lumbar Spine.","ja":"Intracanalicular Osteochondroma in the Lumbar Spine."},"authors":{"en":[{"name":"Shigekiyo Shota"},{"name":"Nishisho Toshihiko"},{"name":"Takata Yoichiro"},{"name":"Toki Shun-ichi"},{"name":"Sugiura Kosuke"},{"name":"Ishihama Yoshihiro"},{"name":"Manabe Hiroaki"},{"name":"Tezuka Fumitake"},{"name":"Yamashita Kazuta"},{"name":"Sakai Toshinori"},{"name":"Maeda Toru"},{"name":"Sairyo Koichi"}],"ja":[{"name":"重清 晶太"},{"name":"西庄 俊彦"},{"name":"髙田 洋一郎"},{"name":"土岐 俊一"},{"name":"杉浦 宏祐"},{"name":"石濱 嘉紘"},{"name":"眞鍋 裕昭"},{"name":"手束 文威"},{"name":"山下 一太"},{"name":"酒井 紀典"},{"name":"前田 徹"},{"name":"西良 浩一"}]},"description":{"en":"resection of the osteochondroma with the ligamentum flavum relieved the symptoms. Spinal osteochondroma occurs relatively frequently in elderly individuals compared with peripheral lesions and mimics a degenerative spinal disorder. Careful physical examination and imaging evaluation can reveal this tumor and surgery is effective for relieving the symptoms.","ja":"resection of the osteochondroma with the ligamentum flavum relieved the symptoms. Spinal osteochondroma occurs relatively frequently in elderly individuals compared with peripheral lesions and mimics a degenerative spinal disorder. Careful physical examination and imaging evaluation can reveal this tumor and surgery is effective for relieving the symptoms."},"publication_date":"2020-01","publication_name":{"en":"NMC Case Report Journal","ja":"NMC Case Report Journal"},"volume":"Vol.7","number":"No.1","starting_page":"11","ending_page":"15","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2176/nmccrj.cr.2019-0031"],"issn":["2188-4226"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:14, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451074"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/31263610","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=362027","label":"url"}],"paper_title":{"en":"A Rare Case of Acute-Onset Spastic Quadriparesis Caused by a Chondroma of the Cervical Spine.","ja":"A Rare Case of Acute-Onset Spastic Quadriparesis Caused by a Chondroma of the Cervical Spine."},"authors":{"en":[{"name":"Momota Kaori"},{"name":"Nishisho Toshihiko"},{"name":"Miyagi Ryo"},{"name":"Toki Shun-ichi"},{"name":"Yamashita Kazuta"},{"name":"Tezuka Fumitake"},{"name":"Takata Yoichiro"},{"name":"Sakai Toshinori"},{"name":"Nagamachi Akihiro"},{"name":"Maeda Toru"},{"name":"Sairyo Koichi"}],"ja":[{"name":"Momota Kaori"},{"name":"西庄 俊彦"},{"name":"宮城 亮"},{"name":"土岐 俊一"},{"name":"山下 一太"},{"name":"手束 文威"},{"name":"髙田 洋一郎"},{"name":"酒井 紀典"},{"name":"長町 顕弘"},{"name":"前田 徹"},{"name":"西良 浩一"}]},"description":{"en":"Chondromas are benign cartilaginous tumors that occur very rarely in the spine. Moreover, chondromas of the extraskeletal origin are also very rare. In this case report, we describe an extremely rare case of chondroma arising from the ligamentum flavum in the cervical spine. A 67-year-old man presented to our clinic with acute-onset spastic quadriparesis. We performed emergent magnetic resonance imaging and found an epidural mass in the right ligamentum flavum at C4-C5. The acute-onset presentation was suspicious for intraligamentous hematoma in the ligamentum flavum at this level. We performed emergency decompression surgery and en bloc removal of the epidural mass with the right C4 and C5 lamina. The lesion had the appearance of cartilaginous tissue rather than hematoma. Based on the histological investigation, the final diagnosis was intraligamentous chondroma of the cervical spine. The quadriparesis improved postoperatively, as did the results of manual muscle testing in the affected area, and he was able to resume walking independently with a cane. At the one-year follow-up, the manual muscle testing results were almost normal. Surgeons should keep in mind the possibility of benign tumors including chondroma of the cervical spine when a patient presents with acute-onset quadriparesis.","ja":"Chondromas are benign cartilaginous tumors that occur very rarely in the spine. Moreover, chondromas of the extraskeletal origin are also very rare. In this case report, we describe an extremely rare case of chondroma arising from the ligamentum flavum in the cervical spine. A 67-year-old man presented to our clinic with acute-onset spastic quadriparesis. We performed emergent magnetic resonance imaging and found an epidural mass in the right ligamentum flavum at C4-C5. The acute-onset presentation was suspicious for intraligamentous hematoma in the ligamentum flavum at this level. We performed emergency decompression surgery and en bloc removal of the epidural mass with the right C4 and C5 lamina. The lesion had the appearance of cartilaginous tissue rather than hematoma. Based on the histological investigation, the final diagnosis was intraligamentous chondroma of the cervical spine. The quadriparesis improved postoperatively, as did the results of manual muscle testing in the affected area, and he was able to resume walking independently with a cane. At the one-year follow-up, the manual muscle testing results were almost normal. Surgeons should keep in mind the possibility of benign tumors including chondroma of the cervical spine when a patient presents with acute-onset quadriparesis."},"publication_date":"2019-05-23","publication_name":{"en":"Case Reports in Orthopedics","ja":"Case Reports in Orthopedics"},"volume":"Vol.2019","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1155/2019/3131628"],"issn":["2090-6749"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:15, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451075"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/113468","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/31064943","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=351819","label":"url"}],"paper_title":{"en":"Intimal sarcoma arising from the common iliac artery presenting with artery occlusion : a case report and literature review.","ja":"Intimal sarcoma arising from the common iliac artery presenting with artery occlusion : a case report and literature review."},"authors":{"en":[{"name":"Kano Masashi"},{"name":"Nishisho Toshihiko"},{"name":"Miyagi Ryo"},{"name":"Chikugo Fumio"},{"name":"Kudo Eiji"},{"name":"Takao Shoichiro"},{"name":"Iwamoto Seiji"},{"name":"Toki Shun-ichi"},{"name":"Sairyo Koichi"}],"ja":[{"name":"Kano Masashi"},{"name":"西庄 俊彦"},{"name":"宮城 亮"},{"name":"Chikugo Fumio"},{"name":"Kudo Eiji"},{"name":"髙尾 正一郎"},{"name":"岩本 誠司"},{"name":"土岐 俊一"},{"name":"西良 浩一"}]},"description":{"en":"We present a rare case of intimal sarcoma arising from the common iliac artery in an 82-year-old man who presented with intermittent claudication. He had undergone endovascular therapy with self-expanding stents to both iliac arteries that had occluded soon after placement. After salvage bypass grafting, a diagnosis of intimal sarcoma with angiosarcoma phenotype from the iliac artery was made. Further bypass graft surgery relieved symptoms temporarily. However, the tumor progressed and the left limb became ischemic. The chemotherapy of eribulin did not prevent tumor progression. The patient died of the disease 20 months after the first surgery. J. Med. Invest. 66 : 205-208, February, 2019.","ja":"We present a rare case of intimal sarcoma arising from the common iliac artery in an 82-year-old man who presented with intermittent claudication. He had undergone endovascular therapy with self-expanding stents to both iliac arteries that had occluded soon after placement. After salvage bypass grafting, a diagnosis of intimal sarcoma with angiosarcoma phenotype from the iliac artery was made. Further bypass graft surgery relieved symptoms temporarily. However, the tumor progressed and the left limb became ischemic. The chemotherapy of eribulin did not prevent tumor progression. The patient died of the disease 20 months after the first surgery. J. Med. Invest. 66 : 205-208, February, 2019."},"publication_date":"2019","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.66","number":"No.1.2","starting_page":"205","ending_page":"208","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.66.205"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:16, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451076"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/29631968","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=340877","label":"url"}],"paper_title":{"en":"Symptomatic Os Intercuneiform: A Case Report.","ja":"Symptomatic Os Intercuneiform: A Case Report."},"authors":{"en":[{"name":"Tonogai Ichiro"},{"name":"Nishisho Toshihiko"},{"name":"Takao Shoichiro"},{"name":"Miyagi Ryo"},{"name":"Yokoyama Kenji"},{"name":"Toki Shunichi"},{"name":"Sairyo Koichi"}],"ja":[{"name":"殿谷 一朗"},{"name":"西庄 俊彦"},{"name":"髙尾 正一郎"},{"name":"宮城 亮"},{"name":"Yokoyama Kenji"},{"name":"Toki Shunichi"},{"name":"西良 浩一"}]},"description":{"en":"We encountered a case of an accessory bone in the foot in the distal portion of the tarsal navicular and the proximal portion of the intermediate cuneiform, namely an os intercuneiform. The patient presented with a history of pain on the dorsal aspect of the left foot, with tenderness and swelling. Perioperative findings revealed a synfibrotic connection between the accessory bone and the navicular and intermediate cuneiform. After unsuccessful conservative treatment, the accessory bone was excised, leading to postoperative symptomatic relief.","ja":"We encountered a case of an accessory bone in the foot in the distal portion of the tarsal navicular and the proximal portion of the intermediate cuneiform, namely an os intercuneiform. The patient presented with a history of pain on the dorsal aspect of the left foot, with tenderness and swelling. Perioperative findings revealed a synfibrotic connection between the accessory bone and the navicular and intermediate cuneiform. After unsuccessful conservative treatment, the accessory bone was excised, leading to postoperative symptomatic relief."},"publication_date":"2018-09","publication_name":{"en":"The Journal of Foot and Ankle Surgery","ja":"The Journal of Foot and Ankle Surgery"},"volume":"Vol.57","number":"No.5","starting_page":"997","ending_page":"999","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1053/j.jfas.2017.11.031"],"issn":["1542-2224"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:17, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451077"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/29117845","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=335905","label":"url"}],"paper_title":{"en":"Restoration of the Active Forearm Rotation Using Vascularized Free Fibular Graft and Radial Head Arthroplasty for a Wide Defect of the Proximal Radius.","ja":"Restoration of the Active Forearm Rotation Using Vascularized Free Fibular Graft and Radial Head Arthroplasty for a Wide Defect of the Proximal Radius."},"authors":{"en":[{"name":"Sato Ryosuke"},{"name":"Hamada Yoshitaka"},{"name":"Hibino Naohito"},{"name":"Nishisho Toshihiko"},{"name":"Tonogai Ichiro"},{"name":"Endo Kenji"},{"name":"Sairyo Koichi"}],"ja":[{"name":"佐藤 亮祐"},{"name":"浜田 佳孝"},{"name":"Hibino Naohito"},{"name":"西庄 俊彦"},{"name":"殿谷 一朗"},{"name":"遠藤 健次"},{"name":"西良 浩一"}]},"description":{"en":"In this report we present a case of re-stabilization of the proximal radius using vascularized free fibular graft combined with anconeus arthroplasty to stabilize the transplanted fibula in a patient with large loss of the proximal radius due to Ewing's sarcoma. A 20-year-old woman had Ewing's sarcoma in the proximal three-fourths of the radius. The resection of large part of the radius containing radial head were necessary for removal of the sarcoma. Reconstruction of the proximal radius was performed using vascularized free fibular graft and the transplanted fibula was stabilized by attaching the anconeus to the proximal edge of the fibula. 2 years after surgery, she had neither recurrence nor metastasis, and achieved functional recovery. The combination anconeus arthroplasty with vascularized free fibular graft can be a good technique for re-stabilization of the elbow and recovery of the forearm function.","ja":"In this report we present a case of re-stabilization of the proximal radius using vascularized free fibular graft combined with anconeus arthroplasty to stabilize the transplanted fibula in a patient with large loss of the proximal radius due to Ewing's sarcoma. A 20-year-old woman had Ewing's sarcoma in the proximal three-fourths of the radius. The resection of large part of the radius containing radial head were necessary for removal of the sarcoma. Reconstruction of the proximal radius was performed using vascularized free fibular graft and the transplanted fibula was stabilized by attaching the anconeus to the proximal edge of the fibula. 2 years after surgery, she had neither recurrence nor metastasis, and achieved functional recovery. The combination anconeus arthroplasty with vascularized free fibular graft can be a good technique for re-stabilization of the elbow and recovery of the forearm function."},"publication_date":"2017-12","publication_name":{"en":"The Journal of Hand Surgery, Asian-Pacific Volume","ja":"The Journal of Hand Surgery, Asian-Pacific Volume"},"volume":"Vol.22","number":"No.4","starting_page":"531","ending_page":"534","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1142/S0218810417720406"],"issn":["2424-8363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:18, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451078"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/28634622","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=332839","label":"url"}],"paper_title":{"en":"Burned-out seminoma revealed by solitary rib bone metastasis.","ja":"Burned-out seminoma revealed by solitary rib bone metastasis."},"authors":{"en":[{"name":"Nishisho Toshihiko"},{"name":"Sakaki Mika"},{"name":"Miyagi Ryo"},{"name":"Takao Shoichiro"},{"name":"Sairyo Koichi"}],"ja":[{"name":"西庄 俊彦"},{"name":"榊 美佳"},{"name":"宮城 亮"},{"name":"髙尾 正一郎"},{"name":"西良 浩一"}]},"description":{"en":"Burned-out tumor is a rare phenomenon in which a testicular tumor regresses in the primary lesion and progresses in a metastatic lesion. We report the case of a 30-year-old male with burned-out seminoma revealed by open biopsy of solitary 10th rib bone metastasis. He underwent inguinal orchiectomy, which revealed hyalinization, indicating a spontaneously regressed testicular tumor. Chemotherapy for seminoma was administered in three cycles of bleomycin + etoposide + cisplatin therapy. The chemotherapy was effective, and wide resection of the rib was subsequently performed. No postoperative chemotherapy was performed, and there has been no evidence of recurrence for 3 years postoperatively.","ja":"Burned-out tumor is a rare phenomenon in which a testicular tumor regresses in the primary lesion and progresses in a metastatic lesion. We report the case of a 30-year-old male with burned-out seminoma revealed by open biopsy of solitary 10th rib bone metastasis. He underwent inguinal orchiectomy, which revealed hyalinization, indicating a spontaneously regressed testicular tumor. Chemotherapy for seminoma was administered in three cycles of bleomycin + etoposide + cisplatin therapy. The chemotherapy was effective, and wide resection of the rib was subsequently performed. No postoperative chemotherapy was performed, and there has been no evidence of recurrence for 3 years postoperatively."},"publication_date":"2017-10","publication_name":{"en":"Skeletal Radiology","ja":"Skeletal Radiology"},"volume":"Vol.46","number":"No.10","starting_page":"1415","ending_page":"1420","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s00256-017-2701-y"],"issn":["1432-2161"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:19, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451079"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/29413783","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=340866","label":"url"}],"paper_title":{"en":"Total calcanectomy for metastasis of renal cell carcinoma in the calcaneus: A case report.","ja":"Total calcanectomy for metastasis of renal cell carcinoma in the calcaneus: A case report."},"authors":{"en":[{"name":"Tonogai Ichiro"},{"name":"Nishisho Toshihiko"},{"name":"Miyagi Ryo"},{"name":"Sairyo Koichi"}],"ja":[{"name":"殿谷 一朗"},{"name":"西庄 俊彦"},{"name":"宮城 亮"},{"name":"西良 浩一"}]},"description":{"en":"We present a rare case of metastasis of renal cell carcinoma to the calcaneus in a 59-year-old man who presented with pain and inability to bear weight on the left foot 3 years after right nephrectomy for renal cell carcinoma. He successfully underwent en bloc resection of his right calcaneus with a limb salvage procedure, total calcanectomy without bony reconstruction. Histological findings identified the lesion as a metastasis originating from a renal cell carcinoma. Recent follow-up examination showed no recurrence. To the best of our knowledge, this is the first reported case to be treated with total calcanectomy for renal cell carcinoma metastasis.","ja":"We present a rare case of metastasis of renal cell carcinoma to the calcaneus in a 59-year-old man who presented with pain and inability to bear weight on the left foot 3 years after right nephrectomy for renal cell carcinoma. He successfully underwent en bloc resection of his right calcaneus with a limb salvage procedure, total calcanectomy without bony reconstruction. Histological findings identified the lesion as a metastasis originating from a renal cell carcinoma. Recent follow-up examination showed no recurrence. To the best of our knowledge, this is the first reported case to be treated with total calcanectomy for renal cell carcinoma metastasis."},"publication_date":"2017-07-06","publication_name":{"en":"Foot and Ankle Surgery","ja":"Foot and Ankle Surgery"},"volume":"Vol.24","number":"No.1","starting_page":"e7","ending_page":"e12","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.fas.2017.06.007"],"issn":["1460-9584"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:20, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451080"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111084","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/28373631","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=324056","label":"url"}],"paper_title":{"en":"Radiographic changes of cervical destructive spondyloarthropathy in long-term hemodialysis patients: A 9-year longitudinal observational study.","ja":"Radiographic changes of cervical destructive spondyloarthropathy in long-term hemodialysis patients: A 9-year longitudinal observational study."},"authors":{"en":[{"name":"Nagamachi Akihiro"},{"name":"Takahashi Mitsuhiko"},{"name":"Mima Noriaki"},{"name":"Adachi Keisuke"},{"name":"Inoue Kazumasa"},{"name":"Jha Subash C"},{"name":"Nitta Akihiro"},{"name":"Morimoto Masatoshi"},{"name":"Takasago Tomoya"},{"name":"Iwame Toshiyuki"},{"name":"Wada Keizo"},{"name":"Tezuka Fumitake"},{"name":"Yamashita Kazuta"},{"name":"Hayashi Fumio"},{"name":"Miyagi Ryo"},{"name":"Nishisho Toshihiko"},{"name":"Tonogai Ichiro"},{"name":"Goto Tomohiro"},{"name":"Takata Yoichiro"},{"name":"Sakai Toshinori"},{"name":"Higashino Kousaku"},{"name":"Chikawa Takashi"},{"name":"Sairyo Koichi"}],"ja":[{"name":"長町 顕弘"},{"name":"高橋 光彦"},{"name":"Mima Noriaki"},{"name":"Adachi Keisuke"},{"name":"Inoue Kazumasa"},{"name":"Jha Subash C"},{"name":"Nitta Akihiro"},{"name":"Morimoto Masatoshi"},{"name":"高砂 智哉"},{"name":"岩目 敏幸"},{"name":"和田 佳三"},{"name":"手束 文威"},{"name":"山下 一太"},{"name":"林 二三男"},{"name":"宮城 亮"},{"name":"西庄 俊彦"},{"name":"殿谷 一朗"},{"name":"後東 知宏"},{"name":"髙田 洋一郎"},{"name":"酒井 紀典"},{"name":"東野 恒作"},{"name":"千川 隆志"},{"name":"西良 浩一"}]},"description":{"en":"Analyses of radiographic changes and clinical symptom of destructive spondyloarthropathy (DSA) on consecutive 42 patients managed with long-term hemodialysis were performed to elucidate radiographic changes of DSA and the factors that influence to the destructive changes. Patients underwent plain radiographs of the cervical spine with 9 years interval. Grading of radiological feature from lateral view was classified into grade 0 to grade 3. Clinical symptom was evaluated using modified Japanese Orthopaedic Association scoring system for cervical myelopathy (mJOA score). Destructive changes were observed in 3 patients at the first examination, and those were observed in 15 patients 9 years after the first examination. There is no statistically significant difference between the duration of hemodialysis and the grade. The mean age at the onset of hemodialysis, however, was significantly higher in patients of grade 2 and 3 than those of grade 1. Older patients with long-term hemodialysis had destructive changes. Destructive changes commonly observed in lower cervical spine. The average numbers of the involved disc level were 1.6 in grade 2 and 1.0 in grade 3. Clinical symptoms were varied in each grade and there was no statistically significant difference in total mJOA score among these grades. J. Med. Invest. 64: 68-73, February, 2017.","ja":"Analyses of radiographic changes and clinical symptom of destructive spondyloarthropathy (DSA) on consecutive 42 patients managed with long-term hemodialysis were performed to elucidate radiographic changes of DSA and the factors that influence to the destructive changes. Patients underwent plain radiographs of the cervical spine with 9 years interval. Grading of radiological feature from lateral view was classified into grade 0 to grade 3. Clinical symptom was evaluated using modified Japanese Orthopaedic Association scoring system for cervical myelopathy (mJOA score). Destructive changes were observed in 3 patients at the first examination, and those were observed in 15 patients 9 years after the first examination. There is no statistically significant difference between the duration of hemodialysis and the grade. The mean age at the onset of hemodialysis, however, was significantly higher in patients of grade 2 and 3 than those of grade 1. Older patients with long-term hemodialysis had destructive changes. Destructive changes commonly observed in lower cervical spine. The average numbers of the involved disc level were 1.6 in grade 2 and 1.0 in grade 3. Clinical symptoms were varied in each grade and there was no statistically significant difference in total mJOA score among these grades. J. Med. Invest. 64: 68-73, February, 2017."},"publication_date":"2017","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.64","number":"No.1.2","starting_page":"68","ending_page":"73","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.64.68"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:21, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451081"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111108","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/28373618","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=324053","label":"url"}],"paper_title":{"en":"Fibroma of tendon sheath on the medial side of the knee: a case report.","ja":"Fibroma of tendon sheath on the medial side of the knee: a case report."},"authors":{"en":[{"name":"Toki Shunichi"},{"name":"Nishisho Toshihiko"},{"name":"Takao Shoichiro"},{"name":"Miyagi Ryo"},{"name":"Tezuka Fumitake"},{"name":"Nagamachi Akihiro"},{"name":"Sairyo Koichi"}],"ja":[{"name":"Toki Shunichi"},{"name":"西庄 俊彦"},{"name":"髙尾 正一郎"},{"name":"宮城 亮"},{"name":"手束 文威"},{"name":"長町 顕弘"},{"name":"西良 浩一"}]},"description":{"en":"Fibroma of tendon sheath, which is a benign soft tissue tumor, primarily affects the finger, hand, or wrist. It rarely involves the knee and only a few cases appear in the literature. Here, we report a case of fibroma of tendon sheath on the medial side of the knee, in a previously hardly reported location, and provide detailed imaging and histological findings. A 54-year-old man presented with his right knee pain and a palpable mass that had developed 3 months earlier. Magnetic resonance imaging showed isointensity in the soft tissue tumor on T1-weighted images, variable intensity on T2-weighted images, and contrast enhancement. The specimen obtained by needle biopsy showed no histological findings of malignancy. Marginal resection was performed and the microscopic diagnosis was fibroma of tendon sheath. Since fibroma of tendon sheath is relatively rare, the radiological feature is not specific, and a rate of local recurrence following excision is high, careful diagnosis, surgical treatment and long-term follow-up are necessary. J. Med. Invest. 64: 173-176, February, 2017.","ja":"Fibroma of tendon sheath, which is a benign soft tissue tumor, primarily affects the finger, hand, or wrist. It rarely involves the knee and only a few cases appear in the literature. Here, we report a case of fibroma of tendon sheath on the medial side of the knee, in a previously hardly reported location, and provide detailed imaging and histological findings. A 54-year-old man presented with his right knee pain and a palpable mass that had developed 3 months earlier. Magnetic resonance imaging showed isointensity in the soft tissue tumor on T1-weighted images, variable intensity on T2-weighted images, and contrast enhancement. The specimen obtained by needle biopsy showed no histological findings of malignancy. Marginal resection was performed and the microscopic diagnosis was fibroma of tendon sheath. Since fibroma of tendon sheath is relatively rare, the radiological feature is not specific, and a rate of local recurrence following excision is high, careful diagnosis, surgical treatment and long-term follow-up are necessary. J. Med. Invest. 64: 173-176, February, 2017."},"publication_date":"2017","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.64","number":"No.1.2","starting_page":"173","ending_page":"176","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.64.173"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:22, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451082"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111434","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26861664","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=311103","label":"url"}],"paper_title":{"en":"Variations in arterial supply to the lower lumbar spine.","ja":"Variations in arterial supply to the lower lumbar spine."},"authors":{"en":[{"name":"Tezuka Fumitake"},{"name":"Sakai Toshinori"},{"name":"Nishisho Toshihiko"},{"name":"Takata Yoichiro"},{"name":"Higashino Kousaku"},{"name":"Takao Shoichiro"},{"name":"Harada Masafumi"},{"name":"Sairyo Koichi"}],"ja":[{"name":"手束 文威"},{"name":"酒井 紀典"},{"name":"西庄 俊彦"},{"name":"髙田 洋一郎"},{"name":"東野 恒作"},{"name":"髙尾 正一郎"},{"name":"原田 雅史"},{"name":"西良 浩一"}]},"description":{"en":"Various distributions of arteries around the lower spine were identified.","ja":"Each segmental artery was visible at the L1-4 spinal levels, running from the vertebra through the lamina in 91.0 % on the right side, in 90.7 % on the left side, while it was visible in 4.6 % on the right side, in 8.7 % on the left side at the L5 level. The extra-osseous arterial supply to the L5 lamina was basically provided by two vessels on each side. One was mostly derived from the L4 segmental artery (right: 92.6 %; left: 92.0 %) that was distributed around the superior articular process, the other was derived from the iliolumbar artery (right: 62.9 %; left: 55.7 %) that was distributed around the inferior articular process through the lamina. There were mainly four combination patterns of those arteries. These combinations, which had been considered as regular patterns in textbooks, were observed in approximately 50 % (right: 55.7 %; left: 48.6 %) of patients."},"publication_date":"2016-12","publication_name":{"en":"European Spine Journal","ja":"European Spine Journal"},"volume":"Vol.25","number":"No.12","starting_page":"4181","ending_page":"4187","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s00586-016-4427-2"],"issn":["1432-0932"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:23, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451083"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111071","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26919624","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84959197843&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=311099","label":"url"}],"paper_title":{"en":"Pigmented villonodular synovitis of the knee joint in a 5-year-old girl treated with combined open and arthroscopic surgery: a case report.","ja":"Pigmented villonodular synovitis of the knee joint in a 5-year-old girl treated with combined open and arthroscopic surgery: a case report."},"authors":{"en":[{"name":"Jha Subash Chandra"},{"name":"Nishisho Toshihiko"},{"name":"Matsuura Tetsuya"},{"name":"Takeuchi Makoto"},{"name":"Miyagi Ryo"},{"name":"Takao Shoichiro"},{"name":"Suzue Naoto"},{"name":"Toki Shunichi"},{"name":"Nagamachi Akihiro"},{"name":"Sairyo Koichi"}],"ja":[{"name":"Jha Subash Chandra"},{"name":"西庄 俊彦"},{"name":"松浦 哲也"},{"name":"Takeuchi Makoto"},{"name":"宮城 亮"},{"name":"髙尾 正一郎"},{"name":"鈴江 直人"},{"name":"Toki Shunichi"},{"name":"長町 顕弘"},{"name":"西良 浩一"}]},"description":{"en":"Pigmented villonodular synovitis is an extremely rare disease in skeletally immature patients. Erosive destruction of the involved joint leads to early arthritis, and its high recurrence rate makes treatment challenging. Multiple surgical approaches exist, but it is unclear as to which among them achieves the lowest possible recurrence rate and morbidity. We report the case of a 5-year-old girl with left knee pain and swelling who was diagnosed with diffuse pigmented villonodular synovitis of the left knee based on MRI findings. Combined open and arthroscopic surgery was performed to completely remove the tumor. Postoperative histopathological examination confirmed the diagnosis of diffuse pigmented villonodular synovitis. The postoperative course was uneventful, with a gradual improvement in symptoms. There were no signs of recurrence on postoperative MRI performed at the 8-month follow-up, with neither knee pain nor limitation of range of motion. The favorable outcome in this case suggests that combined open and arthroscopic surgery may be an effective method for treating pigmented villonodular synovitis in skeletally immature patients.","ja":"Pigmented villonodular synovitis is an extremely rare disease in skeletally immature patients. Erosive destruction of the involved joint leads to early arthritis, and its high recurrence rate makes treatment challenging. Multiple surgical approaches exist, but it is unclear as to which among them achieves the lowest possible recurrence rate and morbidity. We report the case of a 5-year-old girl with left knee pain and swelling who was diagnosed with diffuse pigmented villonodular synovitis of the left knee based on MRI findings. Combined open and arthroscopic surgery was performed to completely remove the tumor. Postoperative histopathological examination confirmed the diagnosis of diffuse pigmented villonodular synovitis. The postoperative course was uneventful, with a gradual improvement in symptoms. There were no signs of recurrence on postoperative MRI performed at the 8-month follow-up, with neither knee pain nor limitation of range of motion. The favorable outcome in this case suggests that combined open and arthroscopic surgery may be an effective method for treating pigmented villonodular synovitis in skeletally immature patients."},"publication_date":"2016-11","publication_name":{"en":"Journal of Pediatric Orthopaedics. Part B","ja":"Journal of Pediatric Orthopaedics. Part B"},"volume":"Vol.25","number":"No.6","starting_page":"564","ending_page":"569","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1097/BPB.0000000000000293"],"issn":["1473-5865"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:24, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451084"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111193","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/27644571","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=322415","label":"url"}],"paper_title":{"en":"Delayed Diagnosis of Primary Bone and Soft Tissue Tumors Initially Treated as Degenerative Spinal Disorders.","ja":"Delayed Diagnosis of Primary Bone and Soft Tissue Tumors Initially Treated as Degenerative Spinal Disorders."},"authors":{"en":[{"name":"Nishisho Toshihiko"},{"name":"Sakai Toshinori"},{"name":"Tezuka Fumitake"},{"name":"Higashino Kosaku"},{"name":"Takao Shoichiro"},{"name":"Takata Yoichiro"},{"name":"Miyagi Ryo"},{"name":"Toki Shunichi"},{"name":"Abe Mitsunobu"},{"name":"Yamashita Kazuta"},{"name":"Nagamachi Akihiro"},{"name":"Sairyo Koichi"}],"ja":[{"name":"西庄 俊彦"},{"name":"酒井 紀典"},{"name":"手束 文威"},{"name":"Higashino Kosaku"},{"name":"髙尾 正一郎"},{"name":"髙田 洋一郎"},{"name":"宮城 亮"},{"name":"Toki Shunichi"},{"name":"阿部 光伸"},{"name":"Yamashita Kazuta"},{"name":"長町 顕弘"},{"name":"西良 浩一"}]},"description":{"en":"Background Symptoms of primary bone and soft tissue tumors located in the trunk mimic those of degenerative spinal disorders such as low back pain or pain or numbness of the legs. Due to their rarity, especially in sarcoma located in the trunk, diagnosis is sometimes delayed. Methods A retrospective review was performed of the records of 383 patients with primary bone and soft tissue tumors who visit our out patient clinic from 2011 to 2013 at a single institution. Patients with delayed diagnosis of primary bone and soft tissue tumors initially treated as degenerative spinal disorders for more than 2 months were identified. Results Of the 383 patients, 5 (1.3%) were initially diagnosed as having degenerative spinal disorders. All 5 patients had bone or soft tissue tumors in the lumbar spine or pelvis. Three patients had a malignant tumor (osteosarcoma, chondrosarcoma, or small round cell sarcoma) at the progressive stage, and 1 died of lung metastasis. Two patients had a benign tumor (aneurysmal bone cyst or simple bone cyst). Conclusions Our findings suggest that when low back pain and leg pain are refractory to conservative treatment, further radiological examination should be conducted. J. Med. Invest. 63: 274-277, August, 2016.","ja":"Background Symptoms of primary bone and soft tissue tumors located in the trunk mimic those of degenerative spinal disorders such as low back pain or pain or numbness of the legs. Due to their rarity, especially in sarcoma located in the trunk, diagnosis is sometimes delayed. Methods A retrospective review was performed of the records of 383 patients with primary bone and soft tissue tumors who visit our out patient clinic from 2011 to 2013 at a single institution. Patients with delayed diagnosis of primary bone and soft tissue tumors initially treated as degenerative spinal disorders for more than 2 months were identified. Results Of the 383 patients, 5 (1.3%) were initially diagnosed as having degenerative spinal disorders. All 5 patients had bone or soft tissue tumors in the lumbar spine or pelvis. Three patients had a malignant tumor (osteosarcoma, chondrosarcoma, or small round cell sarcoma) at the progressive stage, and 1 died of lung metastasis. Two patients had a benign tumor (aneurysmal bone cyst or simple bone cyst). Conclusions Our findings suggest that when low back pain and leg pain are refractory to conservative treatment, further radiological examination should be conducted. J. Med. Invest. 63: 274-277, August, 2016."},"publication_date":"2016","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.63","number":"No.3-4","starting_page":"274","ending_page":"277","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.63.274"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:25, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451085"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111203","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/27644580","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=322413","label":"url"}],"paper_title":{"en":"Complete spontaneous regression of a subpubic cartilaginous cyst: a case report.","ja":"Complete spontaneous regression of a subpubic cartilaginous cyst: a case report."},"authors":{"en":[{"name":"Nishisho Toshihiko"},{"name":"Takao Shoichiro"},{"name":"Miyagi Ryo"},{"name":"Toki Shunichi"},{"name":"Nagamachi Akihiro"},{"name":"Sairyo Koichi"}],"ja":[{"name":"西庄 俊彦"},{"name":"髙尾 正一郎"},{"name":"宮城 亮"},{"name":"Toki Shunichi"},{"name":"長町 顕弘"},{"name":"西良 浩一"}]},"description":{"en":"Subpubic cartilaginous cyst was recently reported as a rare degenerative mass on the pubic symphysis. We report here a 59-year-old woman who presented with a vulvar mass that showed complete spontaneous regression 48 months after the initial visit. Treatment was only wearing brace. This is the first report of complete spontaneous regression of a subpubic cartilaginous cyst. In the case of small subpubic cyst, observation and follow-up alone may be sufficient. J. Med. Invest. 63: 319-322, August, 2016.","ja":"Subpubic cartilaginous cyst was recently reported as a rare degenerative mass on the pubic symphysis. We report here a 59-year-old woman who presented with a vulvar mass that showed complete spontaneous regression 48 months after the initial visit. Treatment was only wearing brace. This is the first report of complete spontaneous regression of a subpubic cartilaginous cyst. In the case of small subpubic cyst, observation and follow-up alone may be sufficient. J. Med. Invest. 63: 319-322, August, 2016."},"publication_date":"2016","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.63","number":"No.3-4","starting_page":"319","ending_page":"322","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.63.319"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:26, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451086"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111146","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/27040046","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84962176073&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=310841","label":"url"}],"paper_title":{"en":"Optimizing baseplate position in reverse total shoulder arthroplasty in small-sized Japanese females: technical notes and literature review.","ja":"Optimizing baseplate position in reverse total shoulder arthroplasty in small-sized Japanese females: technical notes and literature review."},"authors":{"en":[{"name":"C Jha Subash"},{"name":"Fukuta Shoji"},{"name":"Wada Keizo"},{"name":"Higashino Kousaku"},{"name":"Amari-Kita Rui"},{"name":"Tsutsui Takahiko"},{"name":"Goto Tomohiro"},{"name":"Hamada Daisuke"},{"name":"Suzue Naoto"},{"name":"Matsuura Tetsuya"},{"name":"Nishisho Toshihiko"},{"name":"Abe Mitsunobu"},{"name":"Takata Yoichiro"},{"name":"Sakai Toshinori"},{"name":"Nagamachi Akihiro"},{"name":"Sairyo Koichi"}],"ja":[{"name":"C Jha Subash"},{"name":"福田 昇司"},{"name":"Wada Keizo"},{"name":"東野 恒作"},{"name":"Amari-Kita Rui"},{"name":"筒井 貴彦"},{"name":"後東 知宏"},{"name":"浜田 大輔"},{"name":"鈴江 直人"},{"name":"松浦 哲也"},{"name":"西庄 俊彦"},{"name":"阿部 光伸"},{"name":"髙田 洋一郎"},{"name":"酒井 紀典"},{"name":"長町 顕弘"},{"name":"西良 浩一"}]},"description":{"en":"The management of cuff tear arthropathy (CTA) has always been a challenge for shoulder surgeons. Introduction of reverse total shoulder arthroplasty (RTSA) helped in providing pain relief and improved shoulder function in patients with CTA. In this study, we aimed to evaluate the short-term clinical results and some clinical details regarding the types of available prosthesis, positioning, and size of the components for RTSA in a population of short-stature female Japanese. In our seven cases, the average glenoid size was 23.9 mm in width and 34.2 mm in height. The average width was smaller than the size of all available baseplates. We implanted reverse shoulder prostheses with baseplate that measured 28 mm in diameter and two locking screws. The center of the baseplate was shifted to allow slight anterior overhang relative to the anatomical center to avoid breakage of the posterior cortex and to achieve firm fixation. One case of humeral shaft fracture occurred while inserting the humeral stem and required encircling wiring. In our experience, the short term clinical results of RTSA were excellent, but a new prosthesis that is designed to fit the short stature of Asians with smaller glenoid and humerus should be considered. J. Med. Invest. 63: 8-14, February, 2016.","ja":"The management of cuff tear arthropathy (CTA) has always been a challenge for shoulder surgeons. Introduction of reverse total shoulder arthroplasty (RTSA) helped in providing pain relief and improved shoulder function in patients with CTA. In this study, we aimed to evaluate the short-term clinical results and some clinical details regarding the types of available prosthesis, positioning, and size of the components for RTSA in a population of short-stature female Japanese. In our seven cases, the average glenoid size was 23.9 mm in width and 34.2 mm in height. The average width was smaller than the size of all available baseplates. We implanted reverse shoulder prostheses with baseplate that measured 28 mm in diameter and two locking screws. The center of the baseplate was shifted to allow slight anterior overhang relative to the anatomical center to avoid breakage of the posterior cortex and to achieve firm fixation. One case of humeral shaft fracture occurred while inserting the humeral stem and required encircling wiring. In our experience, the short term clinical results of RTSA were excellent, but a new prosthesis that is designed to fit the short stature of Asians with smaller glenoid and humerus should be considered. J. Med. Invest. 63: 8-14, February, 2016."},"publication_date":"2016","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.63","number":"No.1-2","starting_page":"8","ending_page":"14","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.63.8"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:27, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451087"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26067150","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84942613128&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=296698","label":"url"}],"paper_title":{"en":"Tenosynovial Giant Cell Tumor, Diffuse Type/Pigmented Villonodular Synovitis in a Pars Defect: A Case Report.","ja":"Tenosynovial Giant Cell Tumor, Diffuse Type/Pigmented Villonodular Synovitis in a Pars Defect: A Case Report."},"authors":{"en":[{"name":"Kimura Tetsuya"},{"name":"Nishisho Toshihiko"},{"name":"Sakai Toshinori"},{"name":"Miyagi Ryo"},{"name":"Takao Shoichiro"},{"name":"Iwamoto Seiji"},{"name":"Higashino Kosaku"},{"name":"Takata Yoichiro"},{"name":"Goda Yuichiro"},{"name":"Toki Shunichi"},{"name":"Sairyo Koichi"}],"ja":[{"name":"Kimura Tetsuya"},{"name":"西庄 俊彦"},{"name":"酒井 紀典"},{"name":"宮城 亮"},{"name":"髙尾 正一郎"},{"name":"岩本 誠司"},{"name":"Higashino Kosaku"},{"name":"髙田 洋一郎"},{"name":"合田 有一郎"},{"name":"Toki Shunichi"},{"name":"西良 浩一"}]},"description":{"en":"N/A.","ja":"N/A."},"publication_date":"2015-06-15","publication_name":{"en":"Spine","ja":"Spine"},"volume":"Vol.40","number":"No.12","starting_page":"E735","ending_page":"9","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1097/BRS.0000000000000923"],"issn":["1528-1159"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:28, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451088"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111239","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25817277","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84925865792&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=291934","label":"url"}],"paper_title":{"en":"A review of the pathomechanism of forward slippage in pediatric spondylolysis : The Tokushima theory of growth plate slippage","ja":"A review of the pathomechanism of forward slippage in pediatric spondylolysis : The Tokushima theory of growth plate slippage"},"authors":{"en":[{"name":"Sairyo Koichi"},{"name":"Nagamachi Akihiro"},{"name":"Matsuura Tetsuya"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Suzue Naoto"},{"name":"Hamada Daisuke"},{"name":"Takata Yoichiro"},{"name":"Goto Tomohiro"},{"name":"Nishisho Toshihiko"},{"name":"Goda Yuichiro"},{"name":"Tsutsui Takahiko"},{"name":"Tonogai Ichiro"},{"name":"Miyagi Ryo"},{"name":"Abe Mitsunobu"},{"name":"Morimoto Masatoshi"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Higuchi Tadahiro"},{"name":"Hama Shingo"},{"name":"Subash C. Jha"},{"name":"Takahashi Rui"},{"name":"Fukuta Shoji"}],"ja":[{"name":"西良 浩一"},{"name":"Nagamachi Akihiro"},{"name":"松浦 哲也"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"鈴江 直人"},{"name":"浜田 大輔"},{"name":"髙田 洋一郎"},{"name":"後東 知宏"},{"name":"西庄 俊彦"},{"name":"合田 有一郎"},{"name":"筒井 貴彦"},{"name":"殿谷 一朗"},{"name":"宮城 亮"},{"name":"Abe Mitsunobu"},{"name":"Morimoto Masatoshi"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Higuchi Tadahiro"},{"name":"Hama Shingo"},{"name":"Subash C. Jha"},{"name":"Takahashi Rui"},{"name":"Fukuta Shoji"}]},"description":{"en":"Spondylolysis is a stress fracture of the pars interarticularis, which in some cases progresses to spondylolisthesis (forward slippage of the vertebral body). This slip progression is prevalent in children and occurs very rarely after spinal maturation. The pathomechanism and predilection for children remains controversial despite considerable clinical and basic research into the disorder over the last three decades. Here we review the pathomechanism of spondylolytic spondylolisthesis in children and adolescents, and specifically the Tokushima theory of growth plate slippage developed from our extensive research findings. Clinically, we have observed the slippage site near the growth plate on MRI; then, using fresh cadaveric spines, we found the weakest link against forward shear loading was the growth plate. We subsequently developed an immature rat model showing forward slippage after growth plate injury. Moreover, finite element analysis of the pediatric spine clearly showed increased mechanical stress at the growth plate in the spondylolytic pediatric spine model compared with the intact pediatric spine. Thus, spondylolysis progresses to spondylolisthesis (forward slippage) in children and adolescents with the growth plate as the site of the slippage. Repetitive mechanical loading on to the growth plate may serve to separate the growth plate and subsequently progress to spondylolisthesis.","ja":"Spondylolysis is a stress fracture of the pars interarticularis, which in some cases progresses to spondylolisthesis (forward slippage of the vertebral body). This slip progression is prevalent in children and occurs very rarely after spinal maturation. The pathomechanism and predilection for children remains controversial despite considerable clinical and basic research into the disorder over the last three decades. Here we review the pathomechanism of spondylolytic spondylolisthesis in children and adolescents, and specifically the Tokushima theory of growth plate slippage developed from our extensive research findings. Clinically, we have observed the slippage site near the growth plate on MRI; then, using fresh cadaveric spines, we found the weakest link against forward shear loading was the growth plate. We subsequently developed an immature rat model showing forward slippage after growth plate injury. Moreover, finite element analysis of the pediatric spine clearly showed increased mechanical stress at the growth plate in the spondylolytic pediatric spine model compared with the intact pediatric spine. Thus, spondylolysis progresses to spondylolisthesis (forward slippage) in children and adolescents with the growth plate as the site of the slippage. Repetitive mechanical loading on to the growth plate may serve to separate the growth plate and subsequently progress to spondylolisthesis."},"publication_date":"2015-01-23","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.62","number":"No.1,2","starting_page":"11","ending_page":"18","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.62.11"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:29, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451089"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111260","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25817294","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84925876757&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=291921","label":"url"}],"paper_title":{"en":"Percutaneous Endoscopic Lumbar Discectomy for a Huge Herniated Disc Causing Acute Cauda Equina Syndrome : A Case Report","ja":"Percutaneous Endoscopic Lumbar Discectomy for a Huge Herniated Disc Causing Acute Cauda Equina Syndrome : A Case Report"},"authors":{"en":[{"name":"Subash C. Jha"},{"name":"Tonogai Ichiro"},{"name":"Takata Yoichiro"},{"name":"Sakai Toshinori"},{"name":"Higashino Kousaku"},{"name":"Matsuura Tetsuya"},{"name":"Suzue Naoto"},{"name":"Hamada Daisuke"},{"name":"Goto Tomohiro"},{"name":"Nishisho Toshihiko"},{"name":"Tsutsui Takahiko"},{"name":"Goda Yuichiro"},{"name":"Abe Mitsunobu"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Hama Shingo"},{"name":"Higuchi Tadahiro"},{"name":"Fukuta Shoji"},{"name":"Sairyo Koichi"}],"ja":[{"name":"Subash C. Jha"},{"name":"殿谷 一朗"},{"name":"髙田 洋一郎"},{"name":"酒井 紀典"},{"name":"東野 恒作"},{"name":"松浦 哲也"},{"name":"鈴江 直人"},{"name":"浜田 大輔"},{"name":"後東 知宏"},{"name":"西庄 俊彦"},{"name":"筒井 貴彦"},{"name":"合田 有一郎"},{"name":"Abe Mitsunobu"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Hama Shingo"},{"name":"Higuchi Tadahiro"},{"name":"Fukuta Shoji"},{"name":"西良 浩一"}]},"description":{"en":"Microsurgery for lumbar disc herniation that requires surgical intervention has been well described. The methods vary from traditional open discectomy to minimally invasive techniques. All need adequate preanesthetic preparation of patients as general anesthesia is required for the procedure, and nerve monitoring is necessary to prevent iatrogenic nerve injury. Conventional surgical techniques sometimes require the removal of the corresponding lamina to assess the nerve root and herniated disc, and this may increase the risk for posterior instability of the vertebral body. Should this occur, fusion surgery may be needed, further increasing morbidity and cost. We present here a case of lumbar herniated disc fragments causing acute cauda equina syndrome that were endoscopically resected through a transforaminal approach in an awake patient under local anesthesia. Percutaneous endoscopic discectomy under local anesthesia proved to be a better alternative to open back surgery as it made immediate intervention possible, was associated with fewer perioperative complications and morbidity, minimized soft tissue damage, and allowed early rehabilitation with a better outcome and greater patient satisfaction. In addition to these advantages, percutaneous endoscopic discectomy protects other approaches that may be needed in subsequent surgeries, whether open or minimally invasive.","ja":"Microsurgery for lumbar disc herniation that requires surgical intervention has been well described. The methods vary from traditional open discectomy to minimally invasive techniques. All need adequate preanesthetic preparation of patients as general anesthesia is required for the procedure, and nerve monitoring is necessary to prevent iatrogenic nerve injury. Conventional surgical techniques sometimes require the removal of the corresponding lamina to assess the nerve root and herniated disc, and this may increase the risk for posterior instability of the vertebral body. Should this occur, fusion surgery may be needed, further increasing morbidity and cost. We present here a case of lumbar herniated disc fragments causing acute cauda equina syndrome that were endoscopically resected through a transforaminal approach in an awake patient under local anesthesia. Percutaneous endoscopic discectomy under local anesthesia proved to be a better alternative to open back surgery as it made immediate intervention possible, was associated with fewer perioperative complications and morbidity, minimized soft tissue damage, and allowed early rehabilitation with a better outcome and greater patient satisfaction. In addition to these advantages, percutaneous endoscopic discectomy protects other approaches that may be needed in subsequent surgeries, whether open or minimally invasive."},"publication_date":"2015-01-23","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.62","number":"No.1,2","starting_page":"100","ending_page":"102","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.62.100"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:30, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451090"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25611416","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84920972856&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=290037","label":"url"}],"paper_title":{"en":"Local administration of zoledronic Acid for giant cell tumor of bone.","ja":"Local administration of zoledronic Acid for giant cell tumor of bone."},"authors":{"en":[{"name":"Nishisho Toshihiko"},{"name":"Hanaoka Naoyoshi"},{"name":"Miyagi Ryo"},{"name":"Sakai Toshinori"},{"name":"Toki Shunichi"},{"name":"Takahashi Mitsuhiko"},{"name":"Endo Kenji"},{"name":"Yasui Natsuo"},{"name":"Sairyo Koichi"}],"ja":[{"name":"西庄 俊彦"},{"name":"Hanaoka Naoyoshi"},{"name":"宮城 亮"},{"name":"酒井 紀典"},{"name":"Toki Shunichi"},{"name":"高橋 光彦"},{"name":"遠藤 健次"},{"name":"安井 夏生"},{"name":"西良 浩一"}]},"description":{"en":"Giant cell tumor of bone is a locally aggressive tumor with a high local recurrence rate. Several adjuvant therapies have been employed to reduce the recurrence rate, but their effectiveness remains controversial. The authors attempted local administration of zoledronic acid, a nitrogen-containing bisphosphonate that strongly inhibits bone resorption, as an adjuvant treatment for histologically proven giant cell tumor of bone in 5 patients at their institution. After biopsy, 4 patients were treated with local administration of zoledronic acid with artificial bone and 1 was treated with zoledronic acid without artificial bone. Histologic response to the treatment was evaluated with surgically resected specimens. The 4 patients treated with artificial bone showed local control, with histologic tumor necrosis rates of 90%, 90%, 50%, and 10%. Magnetic resonance imaging showed poor gadolinium enhancement, and histologic examination after local zoledronic acid treatment showed tumor necrosis. One patient without artificial bone showed no histologic tumor necrosis and had local recurrence in soft tissue 18 months after tumor resection. A 3-week waiting period between biopsy and zoledronic acid treatment appears reasonable from the histological study. Complication of this therapy was delayed wound healing and it occurred in 2 cases. Taken together, this case series suggests that local administration of zoledronic acid with artificial bone is a potential adjuvant therapy for giant cell tumor of bone. On the other hand, effective local administration of zoledronic acid requires some bone matrix, including artificial bone. Campanacci's grading is important for predicting the effect of local administration of zoledronic acid. [Orthopedics. 2015; 38(1):e25-e30.].","ja":"Giant cell tumor of bone is a locally aggressive tumor with a high local recurrence rate. Several adjuvant therapies have been employed to reduce the recurrence rate, but their effectiveness remains controversial. The authors attempted local administration of zoledronic acid, a nitrogen-containing bisphosphonate that strongly inhibits bone resorption, as an adjuvant treatment for histologically proven giant cell tumor of bone in 5 patients at their institution. After biopsy, 4 patients were treated with local administration of zoledronic acid with artificial bone and 1 was treated with zoledronic acid without artificial bone. Histologic response to the treatment was evaluated with surgically resected specimens. The 4 patients treated with artificial bone showed local control, with histologic tumor necrosis rates of 90%, 90%, 50%, and 10%. Magnetic resonance imaging showed poor gadolinium enhancement, and histologic examination after local zoledronic acid treatment showed tumor necrosis. One patient without artificial bone showed no histologic tumor necrosis and had local recurrence in soft tissue 18 months after tumor resection. A 3-week waiting period between biopsy and zoledronic acid treatment appears reasonable from the histological study. Complication of this therapy was delayed wound healing and it occurred in 2 cases. Taken together, this case series suggests that local administration of zoledronic acid with artificial bone is a potential adjuvant therapy for giant cell tumor of bone. On the other hand, effective local administration of zoledronic acid requires some bone matrix, including artificial bone. Campanacci's grading is important for predicting the effect of local administration of zoledronic acid. [Orthopedics. 2015; 38(1):e25-e30.]."},"publication_date":"2015-01-01","publication_name":{"en":"Orthopedics","ja":"Orthopedics"},"volume":"Vol.38","number":"No.1","starting_page":"e25","ending_page":"30","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3928/01477447-20150105-56"],"issn":["1938-2367"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:31, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451091"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111262","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26399331","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84942058257&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=304937","label":"url"}],"paper_title":{"en":"State-of-the-art ultrasonographic findings in lower extremity sports injuries.","ja":"State-of-the-art ultrasonographic findings in lower extremity sports injuries."},"authors":{"en":[{"name":"Suzue Naoto"},{"name":"Matsuura Tetsuya"},{"name":"Iwame Toshiyuki"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Hamada Daisuke"},{"name":"Goto Tomohiro"},{"name":"Takata Yoichiro"},{"name":"Nishisho Toshihiko"},{"name":"Goda Yuichiro"},{"name":"Tsutsui Takahiko"},{"name":"Tonogai Ichiro"},{"name":"Miyagi Ryo"},{"name":"Abe Mitsunobu"},{"name":"Morimoto Masatoshi"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Higuchi Tadahiro"},{"name":"Hama Shingo"},{"name":"C Jha Subash"},{"name":"Takahashi Rui"},{"name":"Fukuta Shoji"},{"name":"Sairyo Koichi"}],"ja":[{"name":"鈴江 直人"},{"name":"松浦 哲也"},{"name":"Iwame Toshiyuki"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"浜田 大輔"},{"name":"後東 知宏"},{"name":"髙田 洋一郎"},{"name":"西庄 俊彦"},{"name":"合田 有一郎"},{"name":"筒井 貴彦"},{"name":"殿谷 一朗"},{"name":"宮城 亮"},{"name":"阿部 光伸"},{"name":"Morimoto Masatoshi"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Higuchi Tadahiro"},{"name":"Hama Shingo"},{"name":"C Jha Subash"},{"name":"Takahashi Rui"},{"name":"福田 昇司"},{"name":"西良 浩一"}]},"description":{"en":"Athletes sometimes experience overuse injuries. To diagnose these injuries, ultrasonography is often more useful than plain radiography, computed tomography (CT), or magnetic resonance imaging (MRI). Ultrasonography can show both bone and soft tissue from various angles as needed, providing great detail in many cases. In conditions such as osteochondrosis or enthesopathies such as Osgood-Schlatter disease, Sinding-Larsen-Johansson disease, bipartite patella, osteochondritis dissecans of the knee, painful accessory navicular,and jumper's knee, ultrasonography can reveal certain types of bony irregularities or neovascularization of the surrounding tissue. In patients of enthesopathy, ultrasonography can show the degenerative changes at the insertion of the tendon. Given its usefulness in treatment, ultrasonography is expected to become essential in the management of overuse injuries affecting the lower limb in athletes. J. Med. Invest. 62: 109-113, August, 2015.","ja":"Athletes sometimes experience overuse injuries. To diagnose these injuries, ultrasonography is often more useful than plain radiography, computed tomography (CT), or magnetic resonance imaging (MRI). Ultrasonography can show both bone and soft tissue from various angles as needed, providing great detail in many cases. In conditions such as osteochondrosis or enthesopathies such as Osgood-Schlatter disease, Sinding-Larsen-Johansson disease, bipartite patella, osteochondritis dissecans of the knee, painful accessory navicular,and jumper's knee, ultrasonography can reveal certain types of bony irregularities or neovascularization of the surrounding tissue. In patients of enthesopathy, ultrasonography can show the degenerative changes at the insertion of the tendon. Given its usefulness in treatment, ultrasonography is expected to become essential in the management of overuse injuries affecting the lower limb in athletes. J. Med. Invest. 62: 109-113, August, 2015."},"publication_date":"2015","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.62","number":"No.3-4","starting_page":"109","ending_page":"113","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.62.109"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:32, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451092"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111291","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26399355","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84942011242&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=304933","label":"url"}],"paper_title":{"en":"Foraminoplastic transforaminal percutaneous endoscopic discectomy at the lumbosacral junction under local anesthesia in an elite rugby player.","ja":"Foraminoplastic transforaminal percutaneous endoscopic discectomy at the lumbosacral junction under local anesthesia in an elite rugby player."},"authors":{"en":[{"name":"Abe Mitsunobu"},{"name":"Takata Yoichiro"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Matsuura Tetsuya"},{"name":"Suzue Naoto"},{"name":"Hamada Daisuke"},{"name":"Goto Tomohiro"},{"name":"Nishisho Toshihiko"},{"name":"Goda Yuichiro"},{"name":"Tsutsui Takahiko"},{"name":"Tonogai Ichiro"},{"name":"Miyagi Ryo"},{"name":"Morimoto Masatoshi"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Hama Shingo"},{"name":"Higuchi Tadahiro"},{"name":"C Jha Subash"},{"name":"Takahashi Rui"},{"name":"Fukuta Shoji"},{"name":"Sairyo Koichi"}],"ja":[{"name":"阿部 光伸"},{"name":"髙田 洋一郎"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"松浦 哲也"},{"name":"鈴江 直人"},{"name":"浜田 大輔"},{"name":"後東 知宏"},{"name":"西庄 俊彦"},{"name":"合田 有一郎"},{"name":"筒井 貴彦"},{"name":"殿谷 一朗"},{"name":"宮城 亮"},{"name":"Morimoto Masatoshi"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Hama Shingo"},{"name":"Higuchi Tadahiro"},{"name":"C Jha Subash"},{"name":"Takahashi Rui"},{"name":"福田 昇司"},{"name":"西良 浩一"}]},"description":{"en":"Percutaneous endoscopic discectomy (PED) is the least invasive disc surgery available at present. The procedure can be performed under local anesthesia and requires only an 8 mm skin incision. Furthermore, damage to the back muscle is considered minimal, which is particularly important for disc surgery in athletes. However, employing the transforaminal (TF) PED approach at the lumbosacral junction can be challenging due to anatomical constraints imposed by the iliac crest. In such cases, foraminoplasty is required in addition to the standard TF procedure. A 28-year-old man who was a very active rugby player visited us complaining of lower back and left leg pain. His visual analog scale (VAS) score for pain was 8/10 and 3/10, respectively. MRI revealed a herniated nucleus pulposus at L5-S level. TF-PED was planned; however, the anatomy of the iliac crest was later found to prevent access to the herniated mass. Foraminoplasty was therefore performed to enlarge the foramen, thereby allowing a cannula to be passed through the foramen into the canal without causing exiting nerve injury. The herniated mass was then successfully removed via the TF-PED procedure. Pain resolved after surgery, and his VAS score decreased to 0/10 for both back and leg pain. The patient returned to full rugby activity 8 weeks after surgery. In conclusion, even with an intracanalicular herniated mass at the lumbosacral junction, a TF-PED procedure is possible if additional foraminoplasty is adequately performed to enlarge the foramen. J. Med. Invest. 62: 238-241, August, 2015.","ja":"Percutaneous endoscopic discectomy (PED) is the least invasive disc surgery available at present. The procedure can be performed under local anesthesia and requires only an 8 mm skin incision. Furthermore, damage to the back muscle is considered minimal, which is particularly important for disc surgery in athletes. However, employing the transforaminal (TF) PED approach at the lumbosacral junction can be challenging due to anatomical constraints imposed by the iliac crest. In such cases, foraminoplasty is required in addition to the standard TF procedure. A 28-year-old man who was a very active rugby player visited us complaining of lower back and left leg pain. His visual analog scale (VAS) score for pain was 8/10 and 3/10, respectively. MRI revealed a herniated nucleus pulposus at L5-S level. TF-PED was planned; however, the anatomy of the iliac crest was later found to prevent access to the herniated mass. Foraminoplasty was therefore performed to enlarge the foramen, thereby allowing a cannula to be passed through the foramen into the canal without causing exiting nerve injury. The herniated mass was then successfully removed via the TF-PED procedure. Pain resolved after surgery, and his VAS score decreased to 0/10 for both back and leg pain. The patient returned to full rugby activity 8 weeks after surgery. In conclusion, even with an intracanalicular herniated mass at the lumbosacral junction, a TF-PED procedure is possible if additional foraminoplasty is adequately performed to enlarge the foramen. J. Med. Invest. 62: 238-241, August, 2015."},"publication_date":"2015","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.62","number":"No.3-4","starting_page":"238","ending_page":"241","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.62.238"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:33, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451093"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111261","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26399330","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84942025087&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=304925","label":"url"}],"paper_title":{"en":"State of the art: Intraoperative neuromonitoring in spinal deformity surgery.","ja":"State of the art: Intraoperative neuromonitoring in spinal deformity surgery."},"authors":{"en":[{"name":"Takata Yoichiro"},{"name":"Sakai Toshinori"},{"name":"Higashino Kousaku"},{"name":"Matsuura Tetsuya"},{"name":"Suzue Naoto"},{"name":"Hamada Daisuke"},{"name":"Goto Tomohiro"},{"name":"Nishisho Toshihiko"},{"name":"Tsutsui Takahiko"},{"name":"Goda Yuichiro"},{"name":"Morimoto Masatoshi"},{"name":"Abe Mitsunobu"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Hama Shingo"},{"name":"Higuchi Tadahiro"},{"name":"C Jha Subash"},{"name":"Takahashi Rui"},{"name":"Fukuta Shoji"},{"name":"Sairyo Koichi"}],"ja":[{"name":"髙田 洋一郎"},{"name":"酒井 紀典"},{"name":"東野 恒作"},{"name":"松浦 哲也"},{"name":"鈴江 直人"},{"name":"浜田 大輔"},{"name":"後東 知宏"},{"name":"西庄 俊彦"},{"name":"筒井 貴彦"},{"name":"合田 有一郎"},{"name":"Morimoto Masatoshi"},{"name":"阿部 光伸"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Hama Shingo"},{"name":"Higuchi Tadahiro"},{"name":"C Jha Subash"},{"name":"Takahashi Rui"},{"name":"福田 昇司"},{"name":"西良 浩一"}]},"description":{"en":"Application of deformity correction spinal surgery has increased substantially over the past three decades in parallel with improvements in surgical techniques. Intraoperative neuromonitoring (IOM) techniques,including somatosensory evoked potentials (SEPs), muscle evoked potentials (MEPs), and spontaneous electromyography (free-run EMG), have also improved surgical outcome by reducing the risk of iatrogenic neural injury. In this article, we review IOM techniques and their applications in spinal deformity surgery. We also summarize results of selected studies including hundreds of spinal correction surgeries. These studies indicate that multimodal IOM of both motor and sensory responses is superior to either modality alone for reducing the incidence of neural injury during surgery. J. Med. Invest. 62: 103-108, August, 2015.","ja":"Application of deformity correction spinal surgery has increased substantially over the past three decades in parallel with improvements in surgical techniques. Intraoperative neuromonitoring (IOM) techniques,including somatosensory evoked potentials (SEPs), muscle evoked potentials (MEPs), and spontaneous electromyography (free-run EMG), have also improved surgical outcome by reducing the risk of iatrogenic neural injury. In this article, we review IOM techniques and their applications in spinal deformity surgery. We also summarize results of selected studies including hundreds of spinal correction surgeries. These studies indicate that multimodal IOM of both motor and sensory responses is superior to either modality alone for reducing the incidence of neural injury during surgery. J. Med. Invest. 62: 103-108, August, 2015."},"publication_date":"2015","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.62","number":"No.3-4","starting_page":"103","ending_page":"108","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.62.103"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:34, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451094"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25254128","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=285007","label":"url"}],"paper_title":{"en":"Nonunion of the First Sternocostal Synchondrosis Accompanied by Sternoclavicular Joint Synovitis","ja":"Nonunion of the First Sternocostal Synchondrosis Accompanied by Sternoclavicular Joint Synovitis"},"authors":{"en":[{"name":"Makoto Takeuchi"},{"name":"Goto Tomohiro"},{"name":"Yukata Kiminori"},{"name":"Suzue Naoto"},{"name":"Hamada Daisuke"},{"name":"Nishisho Toshihiko"},{"name":"Tonogai Ichiro"},{"name":"Matsuura Tetsuya"},{"name":"Sairyo Koichi"}],"ja":[{"name":"Makoto Takeuchi"},{"name":"後東 知宏"},{"name":"油形 公則"},{"name":"鈴江 直人"},{"name":"浜田 大輔"},{"name":"西庄 俊彦"},{"name":"殿谷 一朗"},{"name":"松浦 哲也"},{"name":"西良 浩一"}]},"description":{"en":"Injury to the sternocostal synchondrosis of the first rib is quite rare. We report one such case in a 50-year-old man with nonunion of the first sternocostal synchondrosis accompanied by synovitis of the sternoclavicular joint. He first underwent arthroscopic surgery of the left sternoclavicular joint. Postoperatively, the patient's symptoms decreased by half, but another pain and crepitus at the inferior lateral portion of the sternoclavicular joint developed. Since MRI and functional CT reexaminations revealed nonunion of the first sternocostal synchondrosis, resection arthroplasty of the first sternocostal joint was performed. This resulted in immediate resolution of the symptoms. At 2-year follow-up, his symptoms disappeared entirely with no limited range of motion of the shoulder.","ja":"Injury to the sternocostal synchondrosis of the first rib is quite rare. We report one such case in a 50-year-old man with nonunion of the first sternocostal synchondrosis accompanied by synovitis of the sternoclavicular joint. He first underwent arthroscopic surgery of the left sternoclavicular joint. Postoperatively, the patient's symptoms decreased by half, but another pain and crepitus at the inferior lateral portion of the sternoclavicular joint developed. Since MRI and functional CT reexaminations revealed nonunion of the first sternocostal synchondrosis, resection arthroplasty of the first sternocostal joint was performed. This resulted in immediate resolution of the symptoms. At 2-year follow-up, his symptoms disappeared entirely with no limited range of motion of the shoulder."},"publication_date":"2014-08-28","publication_name":{"en":"Case Reports in Orthopedics","ja":"Case Reports in Orthopedics"},"volume":"Vol.2014","starting_page":"798329","ending_page":"798329","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1155/2014/798329"],"issn":["2090-6749"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:35, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451095"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/24992065","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=285834","label":"url"}],"paper_title":{"en":"Reverse adipofascial flap after resection of a malignant perineurioma of the forearm.","ja":"Reverse adipofascial flap after resection of a malignant perineurioma of the forearm."},"authors":{"en":[{"name":"Takahashi Mitsuhiko"},{"name":"Kasai Tokio"},{"name":"Nishisho Toshihiko"},{"name":"Takai Michihiro"},{"name":"Endo Hideko"},{"name":"Hirose Takanori"},{"name":"Sairyo Koichi"}],"ja":[{"name":"高橋 光彦"},{"name":"Kasai Tokio"},{"name":"西庄 俊彦"},{"name":"Takai Michihiro"},{"name":"Endo Hideko"},{"name":"Hirose Takanori"},{"name":"西良 浩一"}]},"description":{"en":"The authors describe a patient with recurrent perineurioma arising in the subcutaneous tissue of the dorsal forearm and extending along the forearm fascia. Soft tissue perineurioma is a rare, originally benign peripheral nerve sheath neoplasm arising from the perineurium, a protective cell barrier surrounding the individual fascicles in peripheral nerves. Perineurioma has only recently been recognized as an entity distinct from other nerve sheath tumors, such as schwannoma and neurofibroma, with unique morphologic, ultrastructural, and immunoreactive features. The recurrent tumor had converted into malignant perineurioma, defined as increased nuclear pleomorphism and cellularity. The ill-marginate feature extending along the fascia required wide resection, leaving a substantial defect on the distal forearm. Surgical repair of large forearm skin defects is challenging because of limited skin extensibility for flap creation, the prominence of the site in terms of aesthetic outcome, and the risk of damage to extrinsic muscles that control delicate hand movements. The reverse forearm adipofascial flap, which was based on distal perforators of the radial artery, was suitable for the current case to cover the exposed myotendinous junctions of the forearm extensor muscles. This flap did not sacrifice skin, a major vessel, or skeletal muscles, and preserved function at both the donor and the recipient sites. The texture of the graft was similar to that of the surrounding skin. The clinical and histopathologic features of this rare tumor are also described to aid in the differential diagnosis and as a reference for surgeons who treat soft tissue neoplasms and may encounter this type of soft tumor.","ja":"The authors describe a patient with recurrent perineurioma arising in the subcutaneous tissue of the dorsal forearm and extending along the forearm fascia. Soft tissue perineurioma is a rare, originally benign peripheral nerve sheath neoplasm arising from the perineurium, a protective cell barrier surrounding the individual fascicles in peripheral nerves. Perineurioma has only recently been recognized as an entity distinct from other nerve sheath tumors, such as schwannoma and neurofibroma, with unique morphologic, ultrastructural, and immunoreactive features. The recurrent tumor had converted into malignant perineurioma, defined as increased nuclear pleomorphism and cellularity. The ill-marginate feature extending along the fascia required wide resection, leaving a substantial defect on the distal forearm. Surgical repair of large forearm skin defects is challenging because of limited skin extensibility for flap creation, the prominence of the site in terms of aesthetic outcome, and the risk of damage to extrinsic muscles that control delicate hand movements. The reverse forearm adipofascial flap, which was based on distal perforators of the radial artery, was suitable for the current case to cover the exposed myotendinous junctions of the forearm extensor muscles. This flap did not sacrifice skin, a major vessel, or skeletal muscles, and preserved function at both the donor and the recipient sites. The texture of the graft was similar to that of the surrounding skin. The clinical and histopathologic features of this rare tumor are also described to aid in the differential diagnosis and as a reference for surgeons who treat soft tissue neoplasms and may encounter this type of soft tumor."},"publication_date":"2014-07","publication_name":{"en":"Orthopedics","ja":"Orthopedics"},"volume":"Vol.37","number":"No.7","starting_page":"e661","ending_page":"4","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3928/01477447-20140626-65"],"issn":["1938-2367"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:36, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451096"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25050188","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=285830","label":"url"}],"paper_title":{"en":"Massive femoral osteolysis secondary to loosening of a cemented roughened long stem: a case report.","ja":"Massive femoral osteolysis secondary to loosening of a cemented roughened long stem: a case report."},"authors":{"en":[{"name":"Tamaki Yasuaki"},{"name":"Goto Tomohiro"},{"name":"Hamada Daisuke"},{"name":"Nishisho Toshihiko"},{"name":"Yukata Kiminori"},{"name":"Suzue Naoto"},{"name":"Egawa Hiroshi"},{"name":"Sairyo Koichi"}],"ja":[{"name":"Tamaki Yasuaki"},{"name":"後東 知宏"},{"name":"浜田 大輔"},{"name":"西庄 俊彦"},{"name":"油形 公則"},{"name":"鈴江 直人"},{"name":"江川 洋史"},{"name":"西良 浩一"}]},"description":{"en":"The surface finish of a femoral stem plays an important role in the longevity of cemented total hip arthroplasty. In efforts to decrease the rate of aseptic loosening, some prostheses have been designed to have a roughened surface that enhances bonding between the prosthesis and cement, but clinical outcomes remain controversial. We present a rare case of massive osteolysis with extreme femoral expansion that developed after cemented revision total hip arthroplasty. The destructive changes in the femur were attributable to abnormal motion of the stem and were aggravated by the roughened precoated surface of the long femoral component. Revision surgery using a total femur prosthesis was performed because there was insufficient remaining bone to fix the new prosthesis. The surgical technique involved wrapping polypropylene meshes around the prosthesis to create an insertion for the soft tissue, which proved useful for preventing muscular weakness and subsequent dislocation of the hip.","ja":"The surface finish of a femoral stem plays an important role in the longevity of cemented total hip arthroplasty. In efforts to decrease the rate of aseptic loosening, some prostheses have been designed to have a roughened surface that enhances bonding between the prosthesis and cement, but clinical outcomes remain controversial. We present a rare case of massive osteolysis with extreme femoral expansion that developed after cemented revision total hip arthroplasty. The destructive changes in the femur were attributable to abnormal motion of the stem and were aggravated by the roughened precoated surface of the long femoral component. Revision surgery using a total femur prosthesis was performed because there was insufficient remaining bone to fix the new prosthesis. The surgical technique involved wrapping polypropylene meshes around the prosthesis to create an insertion for the soft tissue, which proved useful for preventing muscular weakness and subsequent dislocation of the hip."},"publication_date":"2014-06-23","publication_name":{"en":"Case Reports in Orthopedics","ja":"Case Reports in Orthopedics"},"volume":"Vol.2014","starting_page":"840267","ending_page":"840267","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1155/2014/840267"],"issn":["2090-6749"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:37, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451097"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/24963428","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=285835","label":"url"}],"paper_title":{"en":"Discoscopic findings of high signal intensity zones on magnetic resonance imaging of lumbar intervertebral discs.","ja":"Discoscopic findings of high signal intensity zones on magnetic resonance imaging of lumbar intervertebral discs."},"authors":{"en":[{"name":"Sugiura Kosuke"},{"name":"Tonogai Ichiro"},{"name":"Matsuura Tetsuya"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Suzue Naoto"},{"name":"Hamada Daisuke"},{"name":"Goto Tomohiro"},{"name":"Takata Yoichiro"},{"name":"Nishisho Toshihiko"},{"name":"Goda Yuichiro"},{"name":"Sato Ryosuke"},{"name":"Kondo Kenji"},{"name":"Tezuka Fumitake"},{"name":"Mineta Kazuaki"},{"name":"Takeuchi Makoto"},{"name":"Takahashi Mitsuhiko"},{"name":"Egawa Hiroshi"},{"name":"Sairyo Koichi"}],"ja":[{"name":"Sugiura Kosuke"},{"name":"殿谷 一朗"},{"name":"松浦 哲也"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"鈴江 直人"},{"name":"浜田 大輔"},{"name":"後東 知宏"},{"name":"髙田 洋一郎"},{"name":"西庄 俊彦"},{"name":"合田 有一郎"},{"name":"佐藤 亮祐"},{"name":"Kondo Kenji"},{"name":"Tezuka Fumitake"},{"name":"Mineta Kazuaki"},{"name":"Takeuchi Makoto"},{"name":"高橋 光彦"},{"name":"江川 洋史"},{"name":"西良 浩一"}]},"description":{"en":"A 32-year-old man underwent radiofrequency thermal annuloplasty (TA) with percutaneous endoscopic discectomy (PED) under local anesthesia for chronic low back pain. His diagnosis was discogenic pain with a high signal intensity zone (HIZ) in the posterior corner of the L4-5 disc. Flexion pain was sporadic, and steroid injection was given twice for severe pain. After the third episode of strong pain, PED and TA were conducted. The discoscope was inserted into the posterior annulus and revealed a migrated white nucleus pulposus which was stained blue. Then, after moving the discoscope to the site of the HIZ, a migrated slightly red nucleus pulposus was found, suggesting inflammation and/or new vessels penetrating the mass. After removing the fragment, the HIZ site was ablated by TA. To our knowledge, this is the first report of the discoscopic findings of HIZ of the lumbar intervertebral disc.","ja":"A 32-year-old man underwent radiofrequency thermal annuloplasty (TA) with percutaneous endoscopic discectomy (PED) under local anesthesia for chronic low back pain. His diagnosis was discogenic pain with a high signal intensity zone (HIZ) in the posterior corner of the L4-5 disc. Flexion pain was sporadic, and steroid injection was given twice for severe pain. After the third episode of strong pain, PED and TA were conducted. The discoscope was inserted into the posterior annulus and revealed a migrated white nucleus pulposus which was stained blue. Then, after moving the discoscope to the site of the HIZ, a migrated slightly red nucleus pulposus was found, suggesting inflammation and/or new vessels penetrating the mass. After removing the fragment, the HIZ site was ablated by TA. To our knowledge, this is the first report of the discoscopic findings of HIZ of the lumbar intervertebral disc."},"publication_date":"2014-05-21","publication_name":{"en":"Case Reports in Orthopedics","ja":"Case Reports in Orthopedics"},"volume":"Vol.2014","starting_page":"245952","ending_page":"245952","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1155/2014/245952"],"issn":["2090-6749"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:38, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451098"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109560","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25264038","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84907519395&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=287280","label":"url"}],"paper_title":{"en":"State of the Art: Transforaminal Approach for Percutaneous Endoscopic Lumbar Discectomy under Local Anesthesia.","ja":"State of the Art: Transforaminal Approach for Percutaneous Endoscopic Lumbar Discectomy under Local Anesthesia."},"authors":{"en":[{"name":"Sairyo Koichi"},{"name":"Egawa Hiroshi"},{"name":"Matsuura Tetsuya"},{"name":"Takahashi Mitsuhiko"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Suzue Naoto"},{"name":"Hamada Daisuke"},{"name":"Goto Tomohiro"},{"name":"Takata Yoichiro"},{"name":"Nishisho Toshihiko"},{"name":"Goda Yuichiro"},{"name":"Sato Ryosuke"},{"name":"Tsutsui Takahiko"},{"name":"Tonogai Ichiro"},{"name":"Kondo Kenji"},{"name":"Tezuka Fumitake"},{"name":"Mineta Kazuaki"},{"name":"Sugiura Kosuke"},{"name":"Takeuchi Makoto"},{"name":"Dezawa Akira"}],"ja":[{"name":"西良 浩一"},{"name":"江川 洋史"},{"name":"松浦 哲也"},{"name":"高橋 光彦"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"鈴江 直人"},{"name":"浜田 大輔"},{"name":"後東 知宏"},{"name":"髙田 洋一郎"},{"name":"西庄 俊彦"},{"name":"合田 有一郎"},{"name":"佐藤 亮祐"},{"name":"筒井 貴彦"},{"name":"殿谷 一朗"},{"name":"Kondo Kenji"},{"name":"Tezuka Fumitake"},{"name":"Mineta Kazuaki"},{"name":"Sugiura Kosuke"},{"name":"Takeuchi Makoto"},{"name":"Dezawa Akira"}]},"description":{"en":"Minimally invasive percutaneous endoscopic discectomy (PED) with a transforaminal approach under local anesthesia was started in the late 20th century. As the procedure requires a skin incision of only 8 mm, it is the least invasive disc surgery procedure at present, and owing to advances in instruments and optics, the use of this technique has gradually spread. In Japan, Dr. Dezawa from Teikyo University Mizonokuchi Hospital introduced this technique in 2003. Thanks to his efforts, the number of surgeons who can perform PED has increased, although the number of active PED surgeons is still only around 20. The first author (K.S.) started PED in 2010. In this review article, we explain the state-of-the-art PED transforaminal technique for minimally invasive disc surgery and present three successful cases. J. Med. Invest. 61: 217-225, August, 2014.","ja":"Minimally invasive percutaneous endoscopic discectomy (PED) with a transforaminal approach under local anesthesia was started in the late 20th century. As the procedure requires a skin incision of only 8 mm, it is the least invasive disc surgery procedure at present, and owing to advances in instruments and optics, the use of this technique has gradually spread. In Japan, Dr. Dezawa from Teikyo University Mizonokuchi Hospital introduced this technique in 2003. Thanks to his efforts, the number of surgeons who can perform PED has increased, although the number of active PED surgeons is still only around 20. The first author (K.S.) started PED in 2010. In this review article, we explain the state-of-the-art PED transforaminal technique for minimally invasive disc surgery and present three successful cases. J. Med. Invest. 61: 217-225, August, 2014."},"publication_date":"2014","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.61","number":"No.3-4","starting_page":"217","ending_page":"225","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.61.217"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:39, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451099"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109561","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25264039","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84907509800&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=287279","label":"url"}],"paper_title":{"en":"The state of the art in arthroscopic hip surgery.","ja":"The state of the art in arthroscopic hip surgery."},"authors":{"en":[{"name":"Goto Tomohiro"},{"name":"Hamada Daisuke"},{"name":"Mineta Kazuaki"},{"name":"Tonogai Ichiro"},{"name":"Egawa Hiroshi"},{"name":"Matsuura Tetsuya"},{"name":"Takahashi Mitsuhiko"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Suzue Naoto"},{"name":"Takata Yoichiro"},{"name":"Nishisho Toshihiko"},{"name":"Goda Yuichiro"},{"name":"Sato Ryosuke"},{"name":"Tezuka Fumitake"},{"name":"Kondo Kenji"},{"name":"Takeuchi Makoto"},{"name":"Sugiura Kousuke"},{"name":"Sairyo Koichi"}],"ja":[{"name":"後東 知宏"},{"name":"浜田 大輔"},{"name":"Mineta Kazuaki"},{"name":"殿谷 一朗"},{"name":"江川 洋史"},{"name":"松浦 哲也"},{"name":"高橋 光彦"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"鈴江 直人"},{"name":"髙田 洋一郎"},{"name":"西庄 俊彦"},{"name":"合田 有一郎"},{"name":"佐藤 亮祐"},{"name":"Tezuka Fumitake"},{"name":"Kondo Kenji"},{"name":"Takeuchi Makoto"},{"name":"Sugiura Kousuke"},{"name":"西良 浩一"}]},"description":{"en":"Hip arthroscopy is among the most rapidly evolving arthroscopic techniques in the last decade and offers the benefits of being both a minimally invasive procedure and an excellent diagnostic tool. Improvements in instrumentation and surgical skills have advanced our ability to accurately diagnose and treat various conditions of the hip joint, and hip arthroscopy has elucidated several pathologies that cause disabling symptoms. Many of these conditions were previously unrecognized and left untreated. The indications for hip arthroscopy include the management of early osteoarthritis, synovial disorders (e. g., synovial osteochondromatosis), labral tears, chondral lesions, and femoroacetabular impingement (FAI), which is increasingly recognized as a disorder that can lead to the development of early cartilage and labral injury. A better understanding of hip arthroscopy, including the anatomy, improved surgical techniques, indications, and complications of the procedure, is essential for its success. This review article discusses the state of the art of arthroscopic hip surgery. J. Med. Invest. 61: 226-232, August, 2014.","ja":"Hip arthroscopy is among the most rapidly evolving arthroscopic techniques in the last decade and offers the benefits of being both a minimally invasive procedure and an excellent diagnostic tool. Improvements in instrumentation and surgical skills have advanced our ability to accurately diagnose and treat various conditions of the hip joint, and hip arthroscopy has elucidated several pathologies that cause disabling symptoms. Many of these conditions were previously unrecognized and left untreated. The indications for hip arthroscopy include the management of early osteoarthritis, synovial disorders (e. g., synovial osteochondromatosis), labral tears, chondral lesions, and femoroacetabular impingement (FAI), which is increasingly recognized as a disorder that can lead to the development of early cartilage and labral injury. A better understanding of hip arthroscopy, including the anatomy, improved surgical techniques, indications, and complications of the procedure, is essential for its success. This review article discusses the state of the art of arthroscopic hip surgery. J. Med. Invest. 61: 226-232, August, 2014."},"publication_date":"2014","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.61","number":"No.3-4","starting_page":"226","ending_page":"232","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.61.226"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:40, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451100"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109562","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25264040","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84907558660&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=287278","label":"url"}],"paper_title":{"en":"State of the art: elbow arthroscopy: review of the literature and application for osteochondritis dissecans of the capitellum.","ja":"State of the art: elbow arthroscopy: review of the literature and application for osteochondritis dissecans of the capitellum."},"authors":{"en":[{"name":"Matsuura Tetsuya"},{"name":"Egawa Hiroshi"},{"name":"Takahashi Mitsuhiko"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Suzue Naoto"},{"name":"Hamada Daisuke"},{"name":"Goto Tomohiro"},{"name":"Takata Yoichiro"},{"name":"Nishisho Toshihiko"},{"name":"Goda Yuichiro"},{"name":"Sato Ryosuke"},{"name":"Tonogai Ichiro"},{"name":"Kondo Kenji"},{"name":"Tezuka Fumitake"},{"name":"Mineta Kazuaki"},{"name":"Sugiura Kosuke"},{"name":"Takeuchi Makoto"},{"name":"Sairyo Koichi"}],"ja":[{"name":"松浦 哲也"},{"name":"江川 洋史"},{"name":"高橋 光彦"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"鈴江 直人"},{"name":"浜田 大輔"},{"name":"後東 知宏"},{"name":"髙田 洋一郎"},{"name":"西庄 俊彦"},{"name":"合田 有一郎"},{"name":"佐藤 亮祐"},{"name":"殿谷 一朗"},{"name":"Kondo Kenji"},{"name":"Tezuka Fumitake"},{"name":"Mineta Kazuaki"},{"name":"Sugiura Kosuke"},{"name":"Takeuchi Makoto"},{"name":"西良 浩一"}]},"description":{"en":"Elbow arthroscopy has become a safe and effective treatment option for a number of elbow disorders. The most rewarding and successful indication is the removal of loose bodies. Loose bodies are often a result of osteochondritis dissecans (OCD) of the capitellum, and arthroscopy in this case is useful for performing debridement, thereby eliminating the need for a more extensive open procedure associated with complications. In this review, we describe our arthroscopic technique for OCD of the capitellum. We usually conduct arthroscopy in the supine position, and use 2.9-mm arthroscopes of 30° and 70°. The 70° arthroscope provides a greater operative field than the 30° arthroscope. Arthroscopic treatment for OCD may require 2 anterior and 2 posterior portals. Loose bodies are commonly found in the radial fossa, coronoid fossa, and in the olecranon fossa. Once the loose bodies are removed, all unstable cartilage of the capitellum lesion is removed to create a stable bed. If any sclerotic changes to the lesion bed are observed, we create microfractures in the lesion bed. The most significant complication in arthroplasty is neurovascular injury. However, we have never experienced this devastating complication, which can be avoided by paying careful attention to detail. J. Med. Invest. 61: 233-240, August, 2014.","ja":"Elbow arthroscopy has become a safe and effective treatment option for a number of elbow disorders. The most rewarding and successful indication is the removal of loose bodies. Loose bodies are often a result of osteochondritis dissecans (OCD) of the capitellum, and arthroscopy in this case is useful for performing debridement, thereby eliminating the need for a more extensive open procedure associated with complications. In this review, we describe our arthroscopic technique for OCD of the capitellum. We usually conduct arthroscopy in the supine position, and use 2.9-mm arthroscopes of 30° and 70°. The 70° arthroscope provides a greater operative field than the 30° arthroscope. Arthroscopic treatment for OCD may require 2 anterior and 2 posterior portals. Loose bodies are commonly found in the radial fossa, coronoid fossa, and in the olecranon fossa. Once the loose bodies are removed, all unstable cartilage of the capitellum lesion is removed to create a stable bed. If any sclerotic changes to the lesion bed are observed, we create microfractures in the lesion bed. The most significant complication in arthroplasty is neurovascular injury. However, we have never experienced this devastating complication, which can be avoided by paying careful attention to detail. J. Med. Invest. 61: 233-240, August, 2014."},"publication_date":"2014","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.61","number":"No.3-4","starting_page":"233","ending_page":"240","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.61.233"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:41, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451101"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109640","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25264043","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84907552794&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=287277","label":"url"}],"paper_title":{"en":"Surgery Related Complications in Percutaneous Endoscopic Lumbar Discectomy under Local Anesthesia.","ja":"Surgery Related Complications in Percutaneous Endoscopic Lumbar Discectomy under Local Anesthesia."},"authors":{"en":[{"name":"Sairyo Koichi"},{"name":"Matsuura Tetsuya"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Takata Yoichiro"},{"name":"Goda Yuichiro"},{"name":"Suzue Naoto"},{"name":"Hamada Daisuke"},{"name":"Goto Tomohiro"},{"name":"Nishisho Toshihiko"},{"name":"Sato Ryosuke"},{"name":"Tsutsui Takahiko"},{"name":"Tonogai Ichiro"},{"name":"Mineta Kazuaki"}],"ja":[{"name":"西良 浩一"},{"name":"松浦 哲也"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"髙田 洋一郎"},{"name":"合田 有一郎"},{"name":"鈴江 直人"},{"name":"浜田 大輔"},{"name":"後東 知宏"},{"name":"西庄 俊彦"},{"name":"佐藤 亮祐"},{"name":"筒井 貴彦"},{"name":"殿谷 一朗"},{"name":"Mineta Kazuaki"}]},"description":{"en":"The minimally invasive percutaneous endoscopic discectomy (PED) as the postero-lateral approach with the local anesthesia was started in the late 20th century. The procedure only requires 8 mm of skin incision; thus, it is the least invasive disc surgery presently. The surgery related complications were reviewed in the initial 100 cases from the single surgeon (K. S., first author). Two cases showed exiting nerve irritation, and complained of leg paresthetic pain for 6 to 12 weeks after the surgery (2.0%). The symptoms got better with medicines. One showed post-surgical epidural hematoma, and required surgical removal of the mass (1.0%). Two cases complained neck pain during surgery (2.0%). Surgeons would be aware of the specific complications for the postero-lateral approach of PED procedure. J. Med. Invest. 61: 264-269, August, 2014.","ja":"The minimally invasive percutaneous endoscopic discectomy (PED) as the postero-lateral approach with the local anesthesia was started in the late 20th century. The procedure only requires 8 mm of skin incision; thus, it is the least invasive disc surgery presently. The surgery related complications were reviewed in the initial 100 cases from the single surgeon (K. S., first author). Two cases showed exiting nerve irritation, and complained of leg paresthetic pain for 6 to 12 weeks after the surgery (2.0%). The symptoms got better with medicines. One showed post-surgical epidural hematoma, and required surgical removal of the mass (1.0%). Two cases complained neck pain during surgery (2.0%). Surgeons would be aware of the specific complications for the postero-lateral approach of PED procedure. J. Med. Invest. 61: 264-269, August, 2014."},"publication_date":"2014","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.61","number":"No.3-4","starting_page":"264","ending_page":"269","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.61.264"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:42, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451102"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109589","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25264059","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84907562798&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=287275","label":"url"}],"paper_title":{"en":"Hybrid technique of cortical bone trajectory and pedicle screwing for minimally invasive spine reconstruction surgery: A technical note.","ja":"Hybrid technique of cortical bone trajectory and pedicle screwing for minimally invasive spine reconstruction surgery: A technical note."},"authors":{"en":[{"name":"Takata Yoichiro"},{"name":"Matsuura Tetsuya"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Mishiro Takuya"},{"name":"Suzue Naoto"},{"name":"Kosaka Hirofumi"},{"name":"Hamada Daisuke"},{"name":"Goto Tomohiro"},{"name":"Nishisho Toshihiko"},{"name":"Goda Yuichiro"},{"name":"Sato Ryosuke"},{"name":"Tsutsui Takahiko"},{"name":"Tonogai Ichiro"},{"name":"Tezuka Fumitake"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Higuchi Tadahiro"},{"name":"Hama Shingo"},{"name":"Sairyo Koichi"}],"ja":[{"name":"髙田 洋一郎"},{"name":"松浦 哲也"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"Mishiro Takuya"},{"name":"鈴江 直人"},{"name":"小坂 浩史"},{"name":"浜田 大輔"},{"name":"後東 知宏"},{"name":"西庄 俊彦"},{"name":"合田 有一郎"},{"name":"佐藤 亮祐"},{"name":"筒井 貴彦"},{"name":"殿谷 一朗"},{"name":"Tezuka Fumitake"},{"name":"Mineta Kazuaki"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Higuchi Tadahiro"},{"name":"Hama Shingo"},{"name":"西良 浩一"}]},"description":{"en":"The pedicle screw (PS) system is widely used for spinal reconstruction. Recently, screw insertion using the cortical bone trajectory (CBT) technique has been reported to provide increased holding strength of the vertebra, even in an osteoporotic spine. CBT is also beneficial due to its low invasiveness. We have been performing hybrid reconstruction with CBT at the cranial level and PS at the caudal level based on the concept of minimal invasiveness. We applied this hybrid technique to 6 cases of degenerative spondylolisthesis. Surgery was completed with a small skin incision of around 5-6 cm, which is shorter than that of the conventional PS procedure. The mean percent slippage before surgery was 19.8%, and this was reduced to 3.9% after surgery and almost maintained 3 months after surgery. Furthermore, no major surgical complications were observed. Here, we introduce the minimally invasive hybrid technique of CBT-PS. Surgeons should be aware of the procedure as an option for minimally invasive lumbar spine reconstructive surgery. J. Med. Invest. 61: 388-392, August, 2014.","ja":"The pedicle screw (PS) system is widely used for spinal reconstruction. Recently, screw insertion using the cortical bone trajectory (CBT) technique has been reported to provide increased holding strength of the vertebra, even in an osteoporotic spine. CBT is also beneficial due to its low invasiveness. We have been performing hybrid reconstruction with CBT at the cranial level and PS at the caudal level based on the concept of minimal invasiveness. We applied this hybrid technique to 6 cases of degenerative spondylolisthesis. Surgery was completed with a small skin incision of around 5-6 cm, which is shorter than that of the conventional PS procedure. The mean percent slippage before surgery was 19.8%, and this was reduced to 3.9% after surgery and almost maintained 3 months after surgery. Furthermore, no major surgical complications were observed. Here, we introduce the minimally invasive hybrid technique of CBT-PS. Surgeons should be aware of the procedure as an option for minimally invasive lumbar spine reconstructive surgery. J. Med. Invest. 61: 388-392, August, 2014."},"publication_date":"2014","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.61","number":"No.3-4","starting_page":"388","ending_page":"392","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.61.388"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:43, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451103"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109596","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25264065","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84907539388&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=287271","label":"url"}],"paper_title":{"en":"Reconstruction of chronic Achilles tendon rupture using the semitendinosus tendon: a case report.","ja":"Reconstruction of chronic Achilles tendon rupture using the semitendinosus tendon: a case report."},"authors":{"en":[{"name":"Takeuchi Makoto"},{"name":"Suzue Naoto"},{"name":"Matsuura Tetsuya"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Hamada Daisuke"},{"name":"Goto Tomohiro"},{"name":"Takata Yoichiro"},{"name":"Nishisho Toshihiko"},{"name":"Goda Yuichiro"},{"name":"Sato Ryosuke"},{"name":"Tonogai Ichiro"},{"name":"Mineta Kazuaki"},{"name":"Sairyo Koichi"}],"ja":[{"name":"Takeuchi Makoto"},{"name":"鈴江 直人"},{"name":"松浦 哲也"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"浜田 大輔"},{"name":"後東 知宏"},{"name":"髙田 洋一郎"},{"name":"西庄 俊彦"},{"name":"合田 有一郎"},{"name":"佐藤 亮祐"},{"name":"殿谷 一朗"},{"name":"Mineta Kazuaki"},{"name":"西良 浩一"}]},"description":{"en":"Achilles tendon rupture is a common trauma requiring surgical management. For chronic Achilles tendon rupture in particular, reconstructive surgery is desirable and several methods have been described. Here we present a case of chronic Achilles tendon rupture reconstructed using the semitendinosus tendon because of the difficulty in pulling down the proximal stump to reach the distal stump and due to an insufficient margin for hooking a suture to the distal stump. Postoperatively, the patient had a fully functional tendon and resumed his normal activities of daily living. Using this surgical technique, we expect favorable outcomes in cases of Achilles tendon rupture. J. Med. Invest. 61: 417-420, August, 2014.","ja":"Achilles tendon rupture is a common trauma requiring surgical management. For chronic Achilles tendon rupture in particular, reconstructive surgery is desirable and several methods have been described. Here we present a case of chronic Achilles tendon rupture reconstructed using the semitendinosus tendon because of the difficulty in pulling down the proximal stump to reach the distal stump and due to an insufficient margin for hooking a suture to the distal stump. Postoperatively, the patient had a fully functional tendon and resumed his normal activities of daily living. Using this surgical technique, we expect favorable outcomes in cases of Achilles tendon rupture. J. Med. Invest. 61: 417-420, August, 2014."},"publication_date":"2014","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.61","number":"No.3-4","starting_page":"417","ending_page":"420","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.61.417"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:44, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451104"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109602","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25264069","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84907506071&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=287269","label":"url"}],"paper_title":{"en":"Efficacy of hip arthroscopy in the diagnosis and treatment of synovial osteochondromatosis: a case report and literature review.","ja":"Efficacy of hip arthroscopy in the diagnosis and treatment of synovial osteochondromatosis: a case report and literature review."},"authors":{"en":[{"name":"Mineta Kazuaki"},{"name":"Goto Tomohiro"},{"name":"Hamada Daisuke"},{"name":"Tsutsui Takahiko"},{"name":"Tonogai Ichiro"},{"name":"Suzue Naoto"},{"name":"Matsuura Tetsuya"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Takata Yoichiro"},{"name":"Nishisho Toshihiko"},{"name":"Sato Ryousuke"},{"name":"Goda Yuichiro"},{"name":"Higuchi Tadahiro"},{"name":"Hama Shingo"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"Sairyo Koichi"}],"ja":[{"name":"Mineta Kazuaki"},{"name":"後東 知宏"},{"name":"浜田 大輔"},{"name":"筒井 貴彦"},{"name":"殿谷 一朗"},{"name":"鈴江 直人"},{"name":"松浦 哲也"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"髙田 洋一郎"},{"name":"西庄 俊彦"},{"name":"Sato Ryousuke"},{"name":"合田 有一郎"},{"name":"Higuchi Tadahiro"},{"name":"Hama Shingo"},{"name":"Kimura Tetsuya"},{"name":"Nitta Akihiro"},{"name":"西良 浩一"}]},"description":{"en":"Here we report a rare case of synovial osteochondromatosis of the hip and provide a brief review of the literature. A 37-year-old woman was referred to our department with a 3-year history of right hip pain. At initial consultation, she complained of pain upon standing and when sitting down, occasional pain at rest and nocturnal pain in the right hip, and worsening of the pain at premenstruum. The range of motion of the affected hip was totally limited by pain. Plain radiography revealed a slightly calcified (or ossified) lesion at the acetabular fossa of the right hip. Computed tomography showed clusters of loose bodies filling the acetabular fossa. Synovial osteochondromatosis was suspected and she underwent hip arthroscopic surgery. Complete resection was performed using the lateral and anterior portals. Postoperatively, her symptoms disappeared entirely and she was discharged 4 days after surgery. The patient regained full range of motion of the right hip and follow-up CT revealed no remaining loose bodies in the right hip. Hip arthroscopy is considered to be effective for the diagnosis and treatment of synovial osteochondromatosis of the hip and is minimally invasive. J. Med. Invest. 61: 436-441, August, 2014.","ja":"Here we report a rare case of synovial osteochondromatosis of the hip and provide a brief review of the literature. A 37-year-old woman was referred to our department with a 3-year history of right hip pain. At initial consultation, she complained of pain upon standing and when sitting down, occasional pain at rest and nocturnal pain in the right hip, and worsening of the pain at premenstruum. The range of motion of the affected hip was totally limited by pain. Plain radiography revealed a slightly calcified (or ossified) lesion at the acetabular fossa of the right hip. Computed tomography showed clusters of loose bodies filling the acetabular fossa. Synovial osteochondromatosis was suspected and she underwent hip arthroscopic surgery. Complete resection was performed using the lateral and anterior portals. Postoperatively, her symptoms disappeared entirely and she was discharged 4 days after surgery. The patient regained full range of motion of the right hip and follow-up CT revealed no remaining loose bodies in the right hip. Hip arthroscopy is considered to be effective for the diagnosis and treatment of synovial osteochondromatosis of the hip and is minimally invasive. J. Med. Invest. 61: 436-441, August, 2014."},"publication_date":"2014","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.61","number":"No.3-4","starting_page":"436","ending_page":"441","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.61.436"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:45, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451105"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=285009","label":"url"}],"paper_title":{"en":"Percutaneous Endoscopic Lumbar Discectomy for Athletes","ja":"Percutaneous Endoscopic Lumbar Discectomy for Athletes"},"authors":{"en":[{"name":"Sairyo Koichi"},{"name":"Matsuura Tetsuya"},{"name":"Higashino Kousaku"},{"name":"Sakai Toshinori"},{"name":"Suzue Naoto"},{"name":"Hamada Daisuke"},{"name":"Goto Tomohiro"},{"name":"Takata Yoichiro"},{"name":"Nishisho Toshihiko"},{"name":"Goda Yuichiro"},{"name":"Sato Ryosuke"},{"name":"Tonogai Ichiro"},{"name":"Tezuka Fumitake"},{"name":"Mineta Kazuaki"},{"name":"Dezawa Akira"}],"ja":[{"name":"西良 浩一"},{"name":"松浦 哲也"},{"name":"東野 恒作"},{"name":"酒井 紀典"},{"name":"鈴江 直人"},{"name":"浜田 大輔"},{"name":"後東 知宏"},{"name":"髙田 洋一郎"},{"name":"西庄 俊彦"},{"name":"合田 有一郎"},{"name":"佐藤 亮祐"},{"name":"殿谷 一朗"},{"name":"Tezuka Fumitake"},{"name":"Mineta Kazuaki"},{"name":"Dezawa Akira"}]},"publication_date":"2013-10","publication_name":{"en":"Journal of Spine","ja":"Journal of Spine"},"languages":["eng"],"referee":true,"identifiers":{"doi":["10.4172/2165-7939.S5-006"],"issn":["2165-7939"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:46, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451106"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23687941","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=274212","label":"url"}],"paper_title":{"en":"Early changes in muscle atrophy and muscle fiber type conversion after spinal cord transection and peripheral nerve transection in rats.","ja":"Early changes in muscle atrophy and muscle fiber type conversion after spinal cord transection and peripheral nerve transection in rats."},"authors":{"en":[{"name":"Higashino Kousaku"},{"name":"Matsuura Tetsuya"},{"name":"Suganuma Katsuyoshi"},{"name":"Yukata Kiminori"},{"name":"Nishisho Toshihiko"},{"name":"Yasui Natsuo"}],"ja":[{"name":"東野 恒作"},{"name":"松浦 哲也"},{"name":"Suganuma Katsuyoshi"},{"name":"油形 公則"},{"name":"西庄 俊彦"},{"name":"安井 夏生"}]},"description":{"en":"BACKGROUND: Spinal cord transection and peripheral nerve transection cause muscle atrophy and muscle fiber type conversion. It is still unknown how spinal cord transection and peripheral nerve transection each affect the differentiation of muscle fiber type conversion mechanism and muscle atrophy. The aim of our study was to evaluate the difference of muscle weight change, muscle fiber type conversion, and Peroxisome proliferator-activated receptor-gamma coactivatior-1alpha (PGC-1alpha) expression brought about by spinal cord transection and by peripheral nerve transection. METHODS: Twenty-four Wistar rats underwent surgery, the control rats underwent a laminectomy; the spinal cord injury group underwent a spinal cord transection; the denervation group underwent a sciatic nerve transection. The rats were harvested of the soleus muscle and the TA muscle at 0 week, 1 week and 2 weeks after surgery. Histological examination was assessed using hematoxylin and eosin (H&E) staining and immunofluorescent staing. Western blot was performed with 3 groups. RESULTS: Both sciatic nerve transection and spinal cord transection caused muscle atrophy with the effect being more severe after sciatic nerve transection. Spinal cord transection caused a reduction in the expression of both sMHC protein and PGC-1alpha protein in the soleus muscle. On the other hand, sciatic nerve transection produced an increase in expression of sMHC protein and PGC-1alpha protein in the soleus muscle. The results of the expression of PGC-1alpha were expected in other words muscle atrophy after sciatic nerve transection is less than after spinal cord transection, however muscle atrophy after sciatic nerve transection was more severe than after spinal cord transection. CONCLUSION: In the conclusion, spinal cord transection diminished the expression of sMHC protein and PGC-1alpha protein in the soleus muscle. On the other hand, sciatic nerve transection enhanced the expression of sMHC protein and PGC-1alpha protein in the soleus muscle.","ja":"BACKGROUND: Spinal cord transection and peripheral nerve transection cause muscle atrophy and muscle fiber type conversion. It is still unknown how spinal cord transection and peripheral nerve transection each affect the differentiation of muscle fiber type conversion mechanism and muscle atrophy. The aim of our study was to evaluate the difference of muscle weight change, muscle fiber type conversion, and Peroxisome proliferator-activated receptor-gamma coactivatior-1alpha (PGC-1alpha) expression brought about by spinal cord transection and by peripheral nerve transection. METHODS: Twenty-four Wistar rats underwent surgery, the control rats underwent a laminectomy; the spinal cord injury group underwent a spinal cord transection; the denervation group underwent a sciatic nerve transection. The rats were harvested of the soleus muscle and the TA muscle at 0 week, 1 week and 2 weeks after surgery. Histological examination was assessed using hematoxylin and eosin (H&E) staining and immunofluorescent staing. Western blot was performed with 3 groups. RESULTS: Both sciatic nerve transection and spinal cord transection caused muscle atrophy with the effect being more severe after sciatic nerve transection. Spinal cord transection caused a reduction in the expression of both sMHC protein and PGC-1alpha protein in the soleus muscle. On the other hand, sciatic nerve transection produced an increase in expression of sMHC protein and PGC-1alpha protein in the soleus muscle. The results of the expression of PGC-1alpha were expected in other words muscle atrophy after sciatic nerve transection is less than after spinal cord transection, however muscle atrophy after sciatic nerve transection was more severe than after spinal cord transection. CONCLUSION: In the conclusion, spinal cord transection diminished the expression of sMHC protein and PGC-1alpha protein in the soleus muscle. On the other hand, sciatic nerve transection enhanced the expression of sMHC protein and PGC-1alpha protein in the soleus muscle."},"publication_date":"2013-05-20","publication_name":{"en":"Journal of Neuroengineering and Rehabilitation","ja":"Journal of Neuroengineering and Rehabilitation"},"volume":"Vol.10","number":"No.1","starting_page":"46","ending_page":"46","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1186/1743-0003-10-46"],"issn":["1743-0003"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:47, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451107"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23585978","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=267978","label":"url"}],"paper_title":{"en":"A massive chondroblastoma in the proximal humerus simulating malignant bone tumors","ja":"A massive chondroblastoma in the proximal humerus simulating malignant bone tumors"},"authors":{"en":[{"name":"Tonogai Ichiro"},{"name":"Takahashi Mitsuhiko"},{"name":"Manabe Hiroaki"},{"name":"Nishisho Toshihiko"},{"name":"Yasui Natsuo"}],"ja":[{"name":"殿谷 一朗"},{"name":"高橋 光彦"},{"name":"眞鍋 裕昭"},{"name":"西庄 俊彦"},{"name":"安井 夏生"}]},"description":{"en":"Chondroblastoma is a mostly benign bone neoplasm that typically affects the second decade of life and exhibits a lytic lesion in the epiphysis of long bones. We report an extreme case of massive, destructive chondroblastoma of the proximal humerus in a 9-year-old girl. It was difficult to differentiate using imaging information the lesion from malignant bone tumors such as osteosarcoma. Histopathological examination from biopsy proved chondroblastoma. The tumor was resected after preoperative transcatheter embolization. Reconstructive procedure for the proximal humerus was not performed due to the local destruction. The present case demonstrates clinical and radiological differentiations of the massive chondroblastoma from the other lesions and histopathological understandings for this lesion.","ja":"Chondroblastoma is a mostly benign bone neoplasm that typically affects the second decade of life and exhibits a lytic lesion in the epiphysis of long bones. We report an extreme case of massive, destructive chondroblastoma of the proximal humerus in a 9-year-old girl. It was difficult to differentiate using imaging information the lesion from malignant bone tumors such as osteosarcoma. Histopathological examination from biopsy proved chondroblastoma. The tumor was resected after preoperative transcatheter embolization. Reconstructive procedure for the proximal humerus was not performed due to the local destruction. The present case demonstrates clinical and radiological differentiations of the massive chondroblastoma from the other lesions and histopathological understandings for this lesion."},"publication_date":"2013-03-25","publication_name":{"en":"Case Reports in Orthopedics","ja":"Case Reports in Orthopedics"},"volume":"Vol.2013","starting_page":"673576","ending_page":"673576","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1155/2013/673576"],"issn":["2090-6749"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:48, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451108"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=290025","label":"url"}],"paper_title":{"en":"An undifferentiated Pleomorphic Sarcoma with Massive Intratumoral Hematoma: A Case Report and Literature Review.","ja":"An undifferentiated Pleomorphic Sarcoma with Massive Intratumoral Hematoma: A Case Report and Literature Review."},"authors":{"en":[{"name":"Sato Ryosuke"},{"name":"Takahashi Mitsuhiko"},{"name":"Nishisho Toshihiko"},{"name":"Endo Kenji"},{"name":"Sairyo Koichi"}],"ja":[{"name":"佐藤 亮祐"},{"name":"高橋 光彦"},{"name":"西庄 俊彦"},{"name":"遠藤 健次"},{"name":"西良 浩一"}]},"publication_date":"2013","publication_name":{"en":"Ann Orthop Rheumatol","ja":"Ann Orthop Rheumatol"},"volume":"Vol.1","number":"No.1","starting_page":"1006","ending_page":"1006","languages":["eng"],"referee":true,"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:49, {"insert":{"user_id":"R000021451","type":"published_papers","id":"32451109"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/22528802","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=247911","label":"url"}],"paper_title":{"en":"Angiogenesis and myogenesis in mouse tibialis anterior muscles during distraction osteogenesis: VEGF, its receptors, and myogenin genes expression.","ja":"Angiogenesis and myogenesis in mouse tibialis anterior muscles during distraction osteogenesis: VEGF, its receptors, and myogenin genes expression."},"authors":{"en":[{"name":"Nishisho Toshihiko"},{"name":"Yukata Kiminori"},{"name":"Matsui Yoshito"},{"name":"Matsuura Tetsuya"},{"name":"Higashino Kousaku"},{"name":"Suganuma K"},{"name":"Nikawa Takeshi"},{"name":"Yasui Natsuo"}],"ja":[{"name":"西庄 俊彦"},{"name":"油形 公則"},{"name":"松井 好人"},{"name":"松浦 哲也"},{"name":"東野 恒作"},{"name":"菅沼 勝義"},{"name":"二川 健"},{"name":"安井 夏生"}]},"description":{"en":"Angiogenesis and myogenesis occur in the surrounding skeletal muscles following distraction osteogenesis, but their molecular mechanisms remain unclear. The present study investigated morphological features of lengthened muscles and the time course change of vascular endothelial growth factor (VEGF), its receptors (VEGFR-1 and VEGFR-2) and myogenin gene expression profiles related to angiogenesis and myogenesis in tibialis anterior (TA) muscles with a mouse model of distraction osteogenesis, which involves 1 week of waiting period (latency phase), 2 weeks of intermittent distraction (distraction phase), and 5 weeks of remodeling period (consolidation phase). Macroscopic findings showed that lengthened TA muscles increased to approximately 42% longer and 10% heavier at the end of the process when compared to pre-surgery. During the distraction phase, VEGF and its receptors were induced in the vascular endothelial cells, myogenin-positive satellite cells and myocytes, and subsequently, capillary progression and myogenesis were increased. Real-time RT-PCR showed that Vegf, Vegfr-1, Vegfr-2, and myogenin genes expression was enhanced during the muscle lengthening. Vegf and Vegfr-1 were upregulated following the recession of angiogenesis at the consolidation phase. We conclude that upregulation of VEGF and its receptors by mechanical tension-stress could be involved in the process of angiogenesis and myogenesis in lengthened muscles. © 2012 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res.","ja":"Angiogenesis and myogenesis occur in the surrounding skeletal muscles following distraction osteogenesis, but their molecular mechanisms remain unclear. The present study investigated morphological features of lengthened muscles and the time course change of vascular endothelial growth factor (VEGF), its receptors (VEGFR-1 and VEGFR-2) and myogenin gene expression profiles related to angiogenesis and myogenesis in tibialis anterior (TA) muscles with a mouse model of distraction osteogenesis, which involves 1 week of waiting period (latency phase), 2 weeks of intermittent distraction (distraction phase), and 5 weeks of remodeling period (consolidation phase). Macroscopic findings showed that lengthened TA muscles increased to approximately 42% longer and 10% heavier at the end of the process when compared to pre-surgery. During the distraction phase, VEGF and its receptors were induced in the vascular endothelial cells, myogenin-positive satellite cells and myocytes, and subsequently, capillary progression and myogenesis were increased. Real-time RT-PCR showed that Vegf, Vegfr-1, Vegfr-2, and myogenin genes expression was enhanced during the muscle lengthening. Vegf and Vegfr-1 were upregulated following the recession of angiogenesis at the consolidation phase. We conclude that upregulation of VEGF and its receptors by mechanical tension-stress could be involved in the process of angiogenesis and myogenesis in lengthened muscles. © 2012 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res."},"publication_date":"2012-04-23","publication_name":{"en":"Journal of Orthopaedic Research","ja":"Journal of Orthopaedic Research"},"volume":"Vol.30","number":"No.11","starting_page":"1767","ending_page":"1773","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1002/jor.22136"],"issn":["1554-527X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
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