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Research

Field of Study

Immunology

Subject of Study

新規アレルギー関与因子の探索 (allergy, T cell, IgE)

Book / Paper

Book:

1. Norio Kamemura :
五訂 食品加工学,
建帛社, 東京都, Apr. 2022.
2. Norio Kamemura :
四訂 食品加工学,
建帛社, 東京都, Apr. 2021.

Academic Paper (Judged Full Paper):

1. Mizobuchi Mizuki, Ishidoh Kazumi and Norio Kamemura :
A comparison of cell death mechanisms of antioxidants, butylated hydroxyanisole and butylated hydroxytoluene,
Drug and Chemical Toxicology, Vol.45, No.4, 1899-1906, 2021.
(DOI: 10.1080/01480545.2021.1894701,   PubMed: 34013795)
2. Miho Kobayashi, Madoka Nishimura, Mina Kawamura, Norio Kamemura, Hideaki Nagamune and Atsushi Tabata :
Change in membrane potential induced by streptolysin O, a pore-forming toxin: flow cytometric analysis using a voltage-sensitive fluorescent probe and rat thymic lymphocytes,
Microbiology and Immunology, Vol.64, No.1, 10-22, 2020.
(DOI: 10.1111/1348-0421.12748,   PubMed: 31584206)
3. Hidekazu Utsunomiya, Riko Hiraishi, Koji Kishimoto, Sari Hamada, Shin Abe, Yusuke Bekki and Norio Kamemura :
Cytotoxicity of Benzophenone-3, an organic UV filter, is caused by increases of intracellular Zn2+ levels in rat thymocytes.,
Chemico-Biological Interactions, Vol.298, 52-56, 2019.
(DOI: 10.1016/j.cbi.2018.10.029,   PubMed: 30391638,   Elsevier: Scopus)
4. Tomoko Inubushi, Mayumi Sugimoto, Haruka Kunimi, Haruka Hino, Atsushi Tabata, Naohiro Imura, Shin Abe and Norio Kamemura :
Biphenyl increases the intracellular Ca2+ concentration in HL-60 cells,
Fundamental Toxicological Sciences, Vol.5, No.3, 99-103, 2018.
(DOI: 10.2131/fts.5.99)
5. Norio Kamemura, Keisuke Oyama, Kaori Kanemaru, Kumio Yokoigawa and Yasuo Oyama :
Diverse cellular actions of tert-butylhydroquinone, a food additive, on rat thymocytes,
Toxicology Research, Vol.6, 922-929, 2017.
(Tokushima University Institutional Repository: 111981,   DOI: 10.1039/C7TX00183E)
6. Norio Kawamoto, Norio Kamemura, Hiroshi Kido and Toshiyuki Fukao :
Detection of ovomucoid-specific low-affinity IgE in infants and its relationship to eczema.,
Pediatric Allergy and Immunology, Vol.28, No.4, 355-361, 2017.
(DOI: 10.1111/pai.12702,   PubMed: 28140473,   Elsevier: Scopus)
7. Norio Kamemura, Sara Murakami, Hiroaki Komatsu, Masahiro Sawanoi, Kenji Miyamoto, Kazumi Ishidoh, Koji Kishimoto, Akihiko Tsuji and Keizo Yuasa :
Type II cGMP-dependent protein kinase negatively regulates fibroblast growth factor signaling by phosphorylating Raf-1 at serine 43 in rat chondrosarcoma cells.,
Biochemical and Biophysical Research Communications, Vol.483, No.1, 82-87, 2017.
(Tokushima University Institutional Repository: 111887,   DOI: 10.1016/j.bbrc.2017.01.001,   PubMed: 28057484,   Elsevier: Scopus)
8. Maki Takeda, Keisuke Oyama, Norio Kamemura, Kaori Kanemaru, Keizo Yuasa, Kumio Yokoigawa and Yasuo Oyama :
Change in plasma membrane potential of rat thymocytes by tert-butylhydroquinone, a food additive: Possible risk on lymphocytes,
Food and Chemical Toxicology, Vol.109, No.1, 296-301, 2017.
(Tokushima University Institutional Repository: 111984,   DOI: 10.1016/j.fct.2017.09.017,   PubMed: 28899772,   Elsevier: Scopus)
9. Mayumi Sugimoto, Norio Kamemura, Mizuho Nagao, Makoto Irahara, Shoji Kagami, Takao Fujisawa and Hiroshi Kido :
Differential response in allergen-specific IgE, IgGs and IgA levels for predicting outcome of oral immunotherapy.,
Pediatric Allergy and Immunology, Vol.27, No.3, 276-282, 2016.
(Tokushima University Institutional Repository: 109691,   DOI: 10.1111/pai.12535,   PubMed: 26764899,   Elsevier: Scopus)
10. Norio Kamemura, Miwa Takashima, Hideaki Morita, Kenji Matsumoto, Hirohisa Saito and Hiroshi Kido :
Measurement of allergen-specific secretory IgA in stool of neonates, infants and toddlers by protection against degradation of immunoglobulins and allergens.,
The Journal of Medical Investigation : JMI, Vol.62, No.3-4, 137-144, 2015.
(Tokushima University Institutional Repository: 109361,   DOI: 10.2152/jmi.62.137,   PubMed: 26399337)
11. Norio Kamemura, Hitomi Tada, Naoki Shimojo, Yoshinori Morita, Yoichi Kohno, Takao Ichioka, Koichi Suzuki, Kenji Kubota, Mineyoshi Hiyoshi and Hiroshi Kido :
Intrauterine sensitization of allergen-specific IgE analyzed by a highly sensitive new allergen microarray.,
The Journal of Allergy and Clinical Immunology, Vol.130, No.1, 113-21.e2, 2012.
(DOI: 10.1016/j.jaci.2012.02.023,   PubMed: 22464644)
12. Tomoko Inubushi, Norio Kamemura, Masataka Oda, Jun Sakurai, Yutaka Nakaya, Nagakatsu Harada, Midori Suenaga, Yoichi Matsunaga, Kazumi Ishidoh and Nobuhiko Katunuma :
L-tryptophan suppresses rise in blood glucose and preserves insulin secretion in type-2 diabetes mellitus rats.,
Journal of Nutritional Science and Vitaminology, Vol.58, No.6, 415-422, 2012.
(DOI: 10.3177/jnsv.58.415,   PubMed: 23419400)
13. Koichi Suzuki, Mineyoshi Hiyoshi, Hitomi Tada, Miwa Bando, Takao Ichioka, Norio Kamemura and Hiroshi Kido :
Allergen diagnosis microarray with high-density immobilization capacity using diamond-like carbon-coated chips for profiling allergen-specific IgE and other immunoglobulins,
Analytica Chimica Acta, Vol.706, No.2, 321-327, 2011.
(DOI: 10.1016/j.aca.2011.08.034,   PubMed: 22023868)

Academic Paper (Unrefereed Paper):

1. Kenta Horimukai, Kumiko Morita, Masami Narita, Mai Kondo, Hiroshi Kitazawa, Makoto Nozaki, Yukiko Shigematsu, Kazue Yoshida, Hironori Niizeki, Ken-Ichiro Motomura, Haruhiko Sago, Tetsuya Takimoto, Eisuke Inoue, Norio Kamemura, Hiroshi Kido, Junzo Hisatsune, Motoyuki Sugai, Hiroyuki Murota, Ichiro Katayama, Takashi Sasaki, Masayuki Amagai, Hideaki Morita, Akio Matsuda, Kenji Matsumoto, Hirohisa Saito and Yukihiro Ohya :
Application of moisturizer to neonates prevents development of atopic dermatitis.,
The Journal of Allergy and Clinical Immunology, Vol.134, No.4, 824-830.e6, 2014.
(DOI: 10.1016/j.jaci.2014.07.060,   PubMed: 25282564)
2. Hiroshi Kido, Norio Kamemura, 窪田 賢司 and 鈴木 宏一 :
高性能タンパクチップの臨床応用ー減感作療法やアレルギー・アトピーの発症予防への応用ー,
日本ラテックスアレルギー研究会会誌, Vol.18, No.2, 10-15, 2014.
3. Kazumi Ishidoh, Norio Kamemura, Takahito Imagawa, Masataka Oda, Jun Sakurai and Nobuhiko Katunuma :
Quinolinate phosphoribosyl transferase, a key enzyme in de novo NAD(+) synthesis, suppresses spontaneous cell death by inhibiting overproduction of active-caspase-3.,
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol.1803, No.5, 527-533, 2010.
(DOI: 10.1016/j.bbamcr.2010.02.007,   PubMed: 20206212)
4. Nobuhiko Katunuma, Kazumi Ishidoh, Jun Sakurai, Masataka Oda and Norio Kamemura :
Reciprocal relationship between the apoptosis pathway mediated by executioner caspases and the physiological NAD synthesis pathway.,
Advances in Enzyme Regulation, Vol.48, 19-30, 2007.
(DOI: 10.1016/j.advenzreg.2007.11.007,   PubMed: 18157947)

Academic Letter:

1. Norio Kamemura, Norio Kawamoto, Ryosuke Nakamura, Reiko Teshima, Toshiyuki Fukao and Hiroshi Kido :
Low-affinity allergen-specific IgE in cord blood and affinity maturation after birth.,
The Journal of Allergy and Clinical Immunology, Vol.133, No.3, 904-5.e6, 2013.
(DOI: 10.1016/j.jaci.2013.09.034,   PubMed: 24231285)
2. Hideaki Morita, Ichiro Nomura, Kanami Orihara, Koichi Yoshida, Akira Akasawa, Hiroshi Tachimoto, Yoshikazu Ohtsuka, Yoshiyuki Namai, Masaki Futamura, Tetsuo Shoda, Akio Matsuda, Norio Kamemura, Hiroshi Kido, Takao Takahashi, Yukihiro Ohya, Hirohisa Saito and Kenji Matsumoto :
Antigen-specific T-cell responses in patients with non-IgE-mediated gastrointestinal food allergy are predominantly skewed to T(H)2.,
The Journal of Allergy and Clinical Immunology, Vol.131, No.2, 590-592, 2012.
(DOI: 10.1016/j.jaci.2012.09.005,   PubMed: 23083674)
3. Hiroshi Kido, 多田 仁美, 澤淵 貴子, Kouichi Suzuki and Norio Kamemura :
アレルゲン同定法の近未来展望,
アレルギー臨床, Vol.29, No.12, 49-53, 2009.

Review, Commentary:

1. Hiroshi Kido, Mayumi Sugimoto, Norio Kamemura, 窪田 賢司 and Kouichi Suzuki :
クラススイッチを基盤に免疫環境と免疫応答をモニターする高性能タンパクチップの臨床応用,
Clinical Immunology & Allergology, Vol.64, No.5, 488-494, Nov. 2015.
2. Hiroshi Kido, 多田 仁美, Norio Kamemura, 窪田 賢司 and Kouichi Suzuki :
アレルゲン特異IgE抗体の新しい測定方法 3. Diamond-Like Carbon を用いた新規高感度アレルゲンマイクロアレイの多項目抗原特異的IgE測定,
アレルギー・免疫, Vol.20, No.1, 56-62, Jan. 2013.
3. Hiroshi Kido, Norio Kamemura, 多田 仁美 and Mineyoshi Hiyoshi :
唾液を用いたアレルギー診断の新技術と今後の展望,
BIO INDUSTRY, Vol.29, No.10, 42-47, Oct. 2012.
4. Kouichi Suzuki, Norio Kamemura, 多田 仁美, 窪田 賢司, 澤淵 貴子 and Hiroshi Kido :
低侵襲性高感度マルチ抗原アレルギー診断チップの開発,
アレルギーの臨床, Vol.32, No.54, 331-335, Jul. 2012.

Proceeding of International Conference:

1. kawamoto Norio, Norio Kamemura, Hiroshi Kido and Fukao Toshiyuki :
Detection of Ovomucoid-Specific Low-Affinity IgE in 14-Month-Old Infants and Its Relationship with Eczema,
American Academy of Allergy Asthma and Immunology, ロサンゼルス (アメリカ合衆国), Mar. 2016.
2. Ohya Yukihiro, Horimukai Kenta, Morita Kumiko, Narita Masami, Niizeki Hironori, Inoue Eisuke, Norio Kamemura, Hiroshi Kido and Saito Hirohisa :
A randomized, controlled intervention trial of early emollient use in prevention of atopic dermatitis and allergic sensitization during infancy,
Collegium Internatuonale Allergologicum, Petersberg, Germany, 91, Sep. 2014.
3. Mayumi Sugimoto, Norio Kamemura, Suzuki Koichi, Kubota Kenji, Nagao Mizuho, Fujisawa Takao, Shoji Kagami and Hiroshi Kido :
Analysis of Allergen-Specific Immunoglobulin in Rush Oral Immunotherapy for Severe Food Allergy by a Highly Sensitive Allergen Microarray,
European Academy of Allergy and Clinical Immunology Congress 2014, Jun. 2014.
4. Naoki Shimojo, Norio Kamemura, Morita Yoshinori, Tada Hitomi, Kubota Kenji, Mineyoshi Hiyoshi, Suzuki Koichi, Ichioka Takao, Kohno Yoichi and Hiroshi Kido :
Allergen sensitization develops in utero: analysis of allergen-specific antibodies by a highly-sensitive new allergen microarray,
European Academy of Allergy and Clinical Immunology Congress 2012, Jun. 2012.

Proceeding of Domestic Conference:

1. Norio Kamemura, Sara Murakami, Hiroaki Komatsu, Masahiro Sawanoi, Kenji Miyamoto, 石堂 一巳, Koji Kishimoto, Akihiko Tsuji and Keizo Yuasa :
軟骨形成におけるcGMP-dependent protein kinase Ⅱの作用機構の探索.,
第58回日本生化学会 中国・四国支部例会, May 2017.
2. Sara Murakami, Norio Kamemura, Hiroaki Komatsu, Akihiko Tsuji and Keizo Yuasa :
PKGIIによるFGF/FGFR/ERK経路阻害機構の解明,
日本農芸化学会中四国支部第46回講演会, Sep. 2016.
3. Hiroaki Komatsu, Norio Kamemura, Akihiko Tsuji and Keizo Yuasa :
PKGIIはRaf1のSer43のリン酸化を介してMAPK経路を負に制御する,
日本農芸化学会2016年度大会, Mar. 2016.
4. Mayumi Sugimoto, Norio Kamemura, 長尾 みづほ, Shoji Kagami, 藤澤 隆夫 and Hiroshi Kido :
急速経口免疫療法における抗原特異的IgGおよびIgAと予後に関する検討,
第64回日本アレルギー学会学術大会, May 2015.
5. Norio Kamemura, noiro kawamoto, 中村 亮介, 手島 玲子, 下条 直樹, 深尾 敏幸 and Hiroshi Kido :
新規蛋白チップによる臍帯血特異的IgEの検出と,離乳完了期までに見られるIgE抗体の低親和性から高親和性への変化,
第51回 日本小児アレルギー学会, 四日市, Nov. 2014.
6. Mayumi Sugimoto, Norio Kamemura, 鈴木 宏一, 窪田 賢司, 長尾 みづほ, 藤澤 隆夫, Shoji Kagami and Hiroshi Kido :
高感度定量測定法による,急速経口免疫療法における抗原特異的免疫グロブリンの検討,
第26回日本アレルギー学会春季臨床大会, May 2014.
7. Norio Kamemura, 多田 仁美, Kouichi Suzuki, 窪田 賢司, 河野 陽一, 下条 直樹, 森田 慶紀, 市橋 隆男 and Hiroshi Kido :
食物,吸入抗原に対する特異的抗体の臍帯血と母体血の関係,
第23回日本アレルギー学界春季臨床大会,千葉(幕張), May 2011.
8. Norio Kamemura, 多田 仁美, 河野 陽一, 下条 直樹, 森田 慶紀, 市岡 隆男, Kouichi Suzuki, 窪田 賢司 and Hiroshi Kido :
臍帯血のアレルゲン特異抗体の検出と各種抗体の母子移行評価 ,,
第23回日本アレルギー学会春季臨床大会, 千葉(幕張), May 2011.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • Development of new methods for the analysis of cytotoxicity by food additives (Project/Area Number: 18K14408 )
  • Alarm signal by dead cells activated progressive properties of tumor cells. (Project/Area Number: 16K01360 )
  • Detection of ovomucoid-specific low-affinity IgE in infants (Project/Area Number: 26860806 )
  • Search by Researcher Number (10632656)