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Tokushima UniversityUniversity HospitalClinical DivisionDepartment of Neurosurgery, Psychiatry and AnesthesiologyPsychiatry
Tokushima UniversityUniversity HospitalClinical DivisionDepartment of Neurosurgery, Psychiatry and AnesthesiologyPsychosomatic Medicine
Tokushima UniversityFaculty of MedicineSchool of MedicineCourse of Integrated Brain SciencesPsychiatry
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Research Activity

Field of Study

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Book / Paper

Book:

1. Makoto Kinoshita :
精神障害各論 器質性精神障害,
株式会社 中外医学社, Jan. 2021.

Academic Paper (Judged Full Paper):

1. Yukiko Tomioka, Makoto Kinoshita, Hidehiro Umehara, Tomohiko Nakayama, Shinya Watanabe, Masahito Nakataki, Shusuke Numata and Tetsuro Ohmori :
Association between serum folate levels and schizophrenia based on sex.,
Psychiatry and Clinical Neurosciences, Vol.74, No.9, 466-471, 2020.
(DOI: 10.1111/pcn.13074,   PubMed: 32445495)
2. Satoshi Okazaki, Shusuke Numata, Ikuo Otsuka, Tadasu Horai, Makoto Kinoshita, Ichiro Sora, Tetsuro Ohmori and Akitoyo Hishimoto :
Decelerated epigenetic aging associated with mood stabilizers in the blood of patients with bipolar disorder.,
Translational Psychiatry, Vol.10, No.1, 129, 2020.
(DOI: 10.1038/s41398-020-0813-y,   PubMed: 32366819)
3. Tomoya Takeda, Masahito Nakataki, Masashi Ohta, S Hamatani, K Matsuura, R Yoshida, Naomi Kameoka, Takeo Tominaga, Hidehiro Umehara, Makoto Kinoshita, Shinya Watanabe, Shusuke Numata, Satsuki Sumitani and Tetsuro Ohmori :
Negative and positive self-thoughts predict subjective quality of life in people with schizophrenia.,
Neuropsychiatric Disease and Treatment, Vol.15, 293-301, 2019.
(Tokushima University Institutional Repository: 113356,   DOI: 10.2147/NDT.S190381,   PubMed: 30718955,   Elsevier: Scopus)
4. Makoto Kinoshita, Masahito Nakataki, Ryoma Morigaki, Satsuki Sumitani, Satoshi Goto, Ryuji Kaji and Tetsuro Ohmori :
Turning on the Left Side Electrode Changed Depressive State to Manic State in a Parkinson's Disease Patient Who Received Bilateral Subthalamic Nucleus Deep Brain Stimulation: A Case Report.,
Clinical Psychopharmacology and Neuroscience, Vol.16, No.4, 494-496, 2018.
(Tokushima University Institutional Repository: 114301,   DOI: 10.9758/cpn.2018.16.4.494,   PubMed: 30466222,   Elsevier: Scopus)
5. Masashi Ohta, Masahito Nakataki, Tomoya Takeda, Shusuke Numata, Takeo Tominaga, Naomi Kameoka, Hiroko Kubo, Makoto Kinoshita, K Matsuura, M Otomo, N Takeichi, Masafumi Harada and Tetsuro Ohmori :
Structural equation modeling approach between salience network dysfunction, depressed mood, and subjective quality of life in schizophrenia: an ICA resting-state fMRI study.,
Neuropsychiatric Disease and Treatment, Vol.14, 1585-1597, 2018.
(Tokushima University Institutional Repository: 113339,   DOI: 10.2147/NDT.S163132,   PubMed: 29942132,   Elsevier: Scopus)
6. Yukiko Tomioka, Shusuke Numata, Makoto Kinoshita, Hidehiro Umehara, Shinya Watanabe, Masahito Nakataki, Y Iwayama, T Toyota, M Ikeda, H Yamamori, S Shimodera, A Tajima, R Hashimoto, N Iwata, T Yoshikawa and Tetsuro Ohmori :
Decreased serum pyridoxal levels in schizophrenia: meta-analysis and Mendelian randomization analysis.,
Journal of Psychiatry & Neuroscience, Vol.43, No.3, 194-200, 2018.
(Tokushima University Institutional Repository: 114064,   DOI: 10.1503/jpn.170053,   PubMed: 29688875)
7. S Okazaki, A Hishimoto, I Otsuka, Y Watanabe, Shusuke Numata, S Boku, N Shimmyo, Makoto Kinoshita, E Inoue, Tetsuro Ohmori, T Someya and I Sora :
Increased serum levels and promoter polymorphisms of macrophage migration inhibitory factor in schizophrenia.,
Progress in Neuro-Psychopharmacology & Biological Psychiatry, Vol.83, 33-41, 2018.
(DOI: 10.1016/j.pnpbp.2018.01.001,   PubMed: 29305329,   Elsevier: Scopus)
8. Masatoshi Inoshita, Hidehiro Umehara, Shinya Watanabe, Masahito Nakataki, Makoto Kinoshita, Yukiko Tomioka, Atsushi Tajima, Shusuke Numata and Tetsuro Ohmori :
Elevated peripheral blood glutamate levels in major depressive disorder.,
Neuropsychiatric Disease and Treatment, Vol.14, 945-953, 2018.
(Tokushima University Institutional Repository: 114063,   DOI: 10.2147/NDT.S159855,   PubMed: 29670355,   Elsevier: Scopus)
9. Sayo Hamatani, Masahito Tomotake, Tomoya Takeda, Naomi Kameoka, Masashi Kawabata, Hiroko Kubo, Masashi Ohta, Yukio Tada, Yukiko Tomioka, Shinya Watanabe, Masatoshi Inoshita, Makoto Kinoshita and Tetsuro Ohmori :
Impaired central coherence in patients with anorexia nervosa,
Psychiatry Research, Vol.259, 77-80, 2017.
(DOI: 10.1016/j.psychres.2017.09.086,   PubMed: 29031167,   Elsevier: Scopus)
10. Hidehiro Umehara, Shusuke Numata, Shinya Watanabe, Yutaka Hatakeyama, Makoto Kinoshita, Yukiko Tomioka, Kiyoshi Nakahara, Takeshi Nikawa and Tetsuro Ohmori :
Altered KYN/TRP, Gln/Glu, and Met/methionine sulfoxide ratios in the blood plasma of medication-free patients with major depressive disorder.,
Scientific Reports, Vol.7, No.1, 4855, 2017.
(Tokushima University Institutional Repository: 110182,   DOI: 10.1038/s41598-017-05121-6,   PubMed: 28687801)
11. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, H Yamamori, Yuka Yasuda, Michiko Fujimoto, Shinya Watanabe, Hidehiro Umehara, Shinji Shimodera, Takanobu Nakazawa, Masataka Kikuchi, Akihiro Nakaya, Hitoshi Hashimoto, Issei Imoto, Ryota Hashimoto and Tetsuro Ohmori :
Effect of Clozapine on DNA Methylation in Peripheral Leukocytes from Patients with Treatment-Resistant Schizophrenia.,
International Journal of Molecular Sciences, Vol.18, No.3, E632, 2017.
(Tokushima University Institutional Repository: 112399,   DOI: 10.3390/ijms18030632,   PubMed: 28335437,   Elsevier: Scopus)
12. Shinya Watanabe, Shusuke Numata, Junichi Iga, Makoto Kinoshita, Hidehiro Umehara, K Ishii and Tetsuro Ohmori :
Gene expression-based biological test for major depressive disorder: an advanced study.,
Neuropsychiatric Disease and Treatment, Vol.13, 535-541, 2017.
(Tokushima University Institutional Repository: 115650,   DOI: 10.2147/NDT.S120038,   PubMed: 28260899,   Elsevier: Scopus)
13. Sayo Hamatani, Masahito Tomotake, Tomoya Takeda, Naomi Kameoka, Masashi Kawabata, Hiroko Kubo, Y Tada, Yukiko Tomioka, Shinya Watanabe, Masatoshi Inoshita, Makoto Kinoshita, Masashi Ohta and Tetsuro Ohmori :
Influence of cognitive function on quality of life in anorexia nervosa patients,
Psychiatry and Clinical Neurosciences, Vol.71, No.5, 328-335, 2017.
(DOI: 10.1111/pcn.12491,   PubMed: 27973723)
14. Hiroko Kubo, Masahito Nakataki, Satsuki Sumitani, Junichi Iga, Shusuke Numata, Naomi Kameoka, Shinya Watanabe, Hidehiro Umehara, Makoto Kinoshita, Masatoshi Inoshita, Mai Tamaru, Masashi Ohta, Chiaki Nakayama-Yamauchi, Yasuhiro Funakoshi, Masafumi Harada and Tetsuro Ohmori :
1H-magnetic resonance spectroscopy study of glutamate-related abnormality in bipolar disorder.,
Journal of Affective Disorders, Vol.208, 139-144, 2017.
(Tokushima University Institutional Repository: 109987,   DOI: 10.1016/j.jad.2016.08.046,   PubMed: 27770643,   Elsevier: Scopus)
15. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Akira Nishi, Sho Muraki, Atsushi Tsuchiya, Hidehiro Umehara, Shinya Watanabe, Issei Imoto and Tetsuro Ohmori :
Cumulative effect of the plasma total homocysteine-related genetic variants on schizophrenia risk.,
Psychiatry Research, Vol.246, 833-837, 2016.
(DOI: 10.1016/j.psychres.2016.10.017,   PubMed: 27810229,   Elsevier: Scopus)
16. JI Iga, Shinya Watanabe, Shusuke Numata, Hidehiro Umehara, Akira Nishi, Makoto Kinoshita, Masatoshi Inoshita, S Shimodera, H Fujita and Tetsuro Ohmori :
Association study of polymorphism in the serotonin transporter gene promoter, methylation profiles, and expression in patients with major depressive disorder.,
Human Psychopharmacology, Vol.31, No.3, 193-199, 2016.
(DOI: 10.1002/hup.2527,   PubMed: 27005686,   Elsevier: Scopus)
17. Hidehiro Umehara, Shusuke Numata, Makoto Kinoshita, Shinya Watanabe, S Nakaaki, Satsuki Sumitani and Tetsuro Ohmori :
No association between BDNF Val66Met polymorphism and treatment response in obsessive-compulsive disorder in the Japanese population.,
Neuropsychiatric Disease and Treatment, Vol.12, 611-615, 2016.
(Tokushima University Institutional Repository: 115651,   DOI: 10.2147/NDT.S102100,   PubMed: 27042072)
18. Shusuke Numata, Makoto Kinoshita, Atsushi Tajima, Akira Nishi, Issei Imoto and Tetsuro Ohmori :
Evaluation of an association between plasma total homocysteine and schizophrenia by a Mendelian randomization analysis.,
BMC Medical Genetics, Vol.16, 54, 2015.
(Tokushima University Institutional Repository: 114763,   DOI: 10.1186/s12881-015-0197-7,   PubMed: 26208850,   Elsevier: Scopus)
19. Masatoshi Inoshita, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, Hidehiro Umehara, Hidenaga Yamamori, Ryota Hashimoto, Issei Imoto and Tetsuro Ohmori :
Sex differences of leukocytes DNA methylation adjusted for estimated cellular proportions.,
Biology of Sex Differences, Vol.6, 11, 2015.
(DOI: 10.1186/s13293-015-0029-7,   PubMed: 26113971,   Elsevier: Scopus)
20. Hidehiro Umehara, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, Shutaro Nakaaki, Issei Imoto, Satsuki Sumitani and Tetsuro Ohmori :
No association between the COMT Val158Met polymorphism and the long-term clinical response in obsessive-compulsive disorder in the Japanese population.,
Human Psychopharmacology, Vol.30, No.5, 372-376, 2015.
(DOI: 10.1002/hup.2485,   PubMed: 26010653,   Elsevier: Scopus)
21. Shinya Watanabe, Junichi Iga, Shusuke Numata, Hidehiro Umehara, Akira Nishi, Makoto Kinoshita, Masatoshi Inoshita and Tetsuro Ohmori :
Polymorphism in the promoter of the gene for the serotonin transporter affects the age of onset of major depressive disorder in the Japanese population.,
Journal of Affective Disorders, Vol.183, 156-158, 2015.
(DOI: 10.1016/j.jad.2015.05.009,   PubMed: 26005777,   Elsevier: Scopus)
22. Shusuke Numata, K Ishii, Atsushi Tajima, Junichi Iga, Makoto Kinoshita, Shinya Watanabe, Hidehiro Umehara, M Fuchikami, S Okada, S Boku, A Hishimoto, S Shimodera, Issei Imoto, S Morinobu and Tetsuro Ohmori :
Blood diagnostic biomarkers for major depressive disorder using multiplex DNA methylation profiles: discovery and validation.,
Epigenetics, Vol.10, No.2, 135-141, 2015.
(DOI: 10.1080/15592294.2014.1003743,   PubMed: 25587773,   Elsevier: Scopus)
23. Akira Nishi, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, K Kikuchi, S Shimodera, Masahito Tomotake, K Ohi, R Hashimoto, Issei Imoto, M Takeda and Tetsuro Ohmori :
Meta-analyses of Blood Homocysteine Levels for Gender and Genetic Association Studies of the MTHFR C677T Polymorphism in Schizophrenia.,
Schizophrenia Bulletin, Vol.40, No.5, 1154-1163, 2014.
(Tokushima University Institutional Repository: 109373,   DOI: 10.1093/schbul/sbt154,   PubMed: 24535549,   Elsevier: Scopus)
24. Y Yoshino, M Abe, Shusuke Numata, S Ochi, Y Mori, T Ishimaru, Makoto Kinoshita, Hidehiro Umehara, K Yamazaki, T Mori, Tetsuro Ohmori and S Ueno :
Missense variants of the alanine:glyoxylate aminotransferase 2 gene are not associated with Japanese schizophrenia patients.,
Progress in Neuro-Psychopharmacology & Biological Psychiatry, Vol.53, 137-141, 2014.
(DOI: 10.1016/j.pnpbp.2014.04.002,   PubMed: 24727203)
25. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Kazutaka Ohi, Ryota Hashimoto, Shinji Shimodera, Issei Imoto, Masatoshi Takeda and Tetsuro Ohmori :
Aberrant DNA Methylation of Blood in Schizophrenia by Adjusting for Estimated Cellular Proportions.,
NeuroMolecular Medicine, Vol.16, No.4, 697-703, 2014.
(DOI: 10.1007/s12017-014-8319-5,   PubMed: 25052007,   Elsevier: Scopus)
26. Shinya Watanabe, Junichi Iga, Akira Nishi, Shusuke Numata, Makoto Kinoshita, K Kikuchi, Masahito Nakataki and Tetsuro Ohmori :
Microarray analysis of global gene expression in leukocytes following lithium treatment.,
Human Psychopharmacology, Vol.29, No.2, 190-198, 2014.
(Tokushima University Institutional Repository: 106183,   DOI: 10.1002/hup.2381,   PubMed: 24590544,   Elsevier: Scopus)
27. J Liu, Shusuke Numata, M Ikeda, Y Watanabe, XB Zheng, X Luo, Makoto Kinoshita, A Nunokawa, T Someya, Tetsuro Ohmori, JX Bei, SA Chong, J Lee, Z Li, J Liu, N Iwata, Y Shi, M Li and B Su :
An evaluation of association between a novel hippocampal biology related SNP (rs7294919) and schizophrenia.,
PLoS ONE, Vol.8, No.11, e80696, 2013.
(DOI: 10.1371/journal.pone.0080696,   PubMed: 24278305,   Elsevier: Scopus)
28. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Shinji Shimodera, Issei Imoto and Tetsuro Ohmori :
Plasma total homocysteine is associated with DNA methylation in patients with schizophrenia.,
Epigenetics, Vol.8, No.6, 584-590, 2013.
(DOI: 10.4161/epi.24621,   PubMed: 23774737,   Elsevier: Scopus)
29. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, S Shimodera, S Ono, A Imamura, Junichi Iga, Shinya Watanabe, Kumiko Kikuchi, Hiroko Kubo, Masahito Nakataki, Satsuki Sumitani, Issei Imoto, Y Okazaki and Tetsuro Ohmori :
DNA Methylation Signatures of Peripheral Leukocytes in Schizophrenia.,
NeuroMolecular Medicine, Vol.Mar;15, No.1, 95-101, 2013.
(Tokushima University Institutional Repository: 106144,   DOI: 10.1007/s12017-012-8198-6,   PubMed: 22961555,   Elsevier: Scopus)
30. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, K Ohi, R Hashimoto, S Shimodera, Issei Imoto, Mitsuo Itakura, M Takeda and Tetsuro Ohmori :
Meta-analysis of association studies between DISC1 missense variants and schizophrenia in the Japanese population.,
Schizophrenia Research, Vol.141, No.2-3, 271-273, 2012.
(DOI: 10.1016/j.schres.2012.07.020,   PubMed: 22901592)
31. Makoto Kinoshita, Masahito Nakataki, Satsuki Sumitani and Tetsuro Ohmori :
両側視床下核深部脳刺激術を施行され左側電極Onによってうつ状態から躁状態に転じたパーキンソン病の一例,
Psychiatria et Neurologia Japonica, Vol.114, No.4, 468, 2012.

Review, Commentary:

1. Makoto Kinoshita, Shusuke Numata and Tetsuro Ohmori :
精神疾患における末梢血所見と死後脳所見の比較,
Japanese Journal of Biological Psychiatry, Vol.30, No.4, 157-162, 2019.
(DOI: 10.11249/jsbpjjpp.30.4_157,   CiNii: 130007821992)
2. Shusuke Numata and Makoto Kinoshita :
ここまでわかった統合失調症の病態メカニズム,
Mebio(メジカルビュー社), Vol.32, No.10, 4-10, 2015.
3. Shusuke Numata, Makoto Kinoshita and Tetsuro Ohmori :
統合失調症のDNAメチル化修飾異常,
Japanese Journal of Biological Psychiatry, Vol.26, No.1, 7-14, 2015.
(DOI: 10.11249/jsbpjjpp.26.1_7)
4. Shusuke Numata, Makoto Kinoshita and Tetsuro Ohmori :
バイオマーカー探索による治療抵抗性統合失調症へのアプローチ,
Rinsyo Seisin Yakuri, Vol.17, 1645-1650, 2014.

Proceeding of International Conference:

1. Shinya Watanabe, Hidehiro Umehara, Yukiko Tomioka, Makoto Kinoshita, Masahito Nakataki, Shusuke Numata and Tetsuro Ohmori :
Effects of processing conditions on plasma L-glutamate levels in non-psychiatric healthy subjects.,
6th Congress of AsCNP Asian College of Neuropsychopharmacology, Fukuoka, Oct. 2019.
2. Masashi Ohta, Masahito Nakataki, Tomoya Takeda, Shusuke Numata, Takeo Tominaga, Naomi Kameoka, Hiroko Kubo, Makoto Kinoshita, Matsuura Kanae, Maki Ohtomo, Takeichi Naoya, Masafumi Harada and Tetsuro Ohmori :
Causal relationship between salience network dysfunction, depressed mood, and subjective quality of life in schizophrenia.,
6th Congress of AsCNP Asian College of Neuropsychopharmacology, Fukuoka, Oct. 2019.
3. Makoto Kinoshita, E Candemir, S Kittel-Schneider, A Reif and F Freudenberg :
A gene expression study of the glutamate-nitric oxide pathway in schizophrenia,
European College of Neuropsychopharmacology, Barcelona, Spain, Oct. 2018.
4. Hidehiro Umehara, Shinya Watanabe, Makoto Kinoshita, Shusuke Numata and Tetsuro Ohmori :
Pharmacometabolomic changes following antidepressants in patients with major depressive disorder.,
5th Congress of Asian College of Neuropsychopharmacology, Indonesia, Apr. 2017.
5. Shinya Watanabe, Hidehiro Umehara, Makoto Kinoshita, Kazuo Ishii, Shusuke Numata and Tetsuro Ohmori :
Gene expression-based diagnostic marker for bipolar disorder.,
5th Congress of Asian College of Neuropsychopharmacology, Indonesia, Apr. 2017.
6. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Hidenaga Yamamori, Yuka Yasuda, Michiko Fujimoto, Issei Imoto, Ryota Hashimoto and Tetsuro Ohmori :
DNA methylation changes in leukocytes by clozapine treatment in patients with treatment-resistant schizophrenia.,
Society for Neuroscience 2016 annual Meeting, San Diego, Nov. 2016.
7. Shusuke Numata, Makoto Kinoshita, Atsushi Tajima, K OHI, R HASHIMOTO, S SHIMODERA, Issei Imoto, M TAKEDA and Tetsuro Ohmori :
The effect of blood cellular heterogeneity on DNA methylation in schizophrenia,
Neuroscience, Chicago, Oct. 2015.
8. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, A NISHI, Issei Imoto and Tetsuro Ohmori :
Genome-wide association study of plasma total homocysisteine in schizophrenia,
Neuroscience, Chicago, Oct. 2015.
9. A NISHI, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, S SHIMODERA, S ONO, S OCHI, N KUROTAKI, A IMAMURA, Shu-ichi Ueno, Issei Imoto and Tetsuro Ohmori :
Trio-based exome sequencing identified de novo non-synonymous missense mutations in schizophrenia.,
Neuroscience, Chicago, Oct. 2015.
10. Shusuke Numata, Ishii Kazuo, Atsushi Tajima, Junichi Iga, Makoto Kinoshita, Shinya Watanabe, Hidehiro Umehara, Fuchikami Manabu, Okada Satoshi, Shimodera Shinji, Issei Imoto, Morinobu Shigeru and Tetsuro Ohmori :
Blood diagnostic biomarkers for major depressive disorder using DNA methylation profiles.,
Neuroscience, Washington DC, Nov. 2014.
11. Masatoshi Inoshita, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, Issei Imoto and Tetsuro Ohmori :
Sex differences of blood in DNA methylation.,
Neuroscience, Washington DC, Nov. 2014.
12. Hidehiro Umehara, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, Nakaaki Shutaro, Issei Imoto, Satsuki Sumitani and Tetsuro Ohmori :
Association between the COMT Val158Met polymorphism and the clinical response to SSRI or SSRI with antipsychotics in obsessive-compulsive disorder.,
Neuroscience, Washington DC, Nov. 2014.
13. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Nishi Akira, Issei Imoto and Tetsuro Ohmori :
Blood homocysteine and schizophrenia evaluated by a Mendelian randomization analysis.,
Neuroscience, Washington DC, Nov. 2014.
14. Makoto Kinoshita :
DNA methylation and Schizophrenia.,
Taiwanese Society of Biological Psychiatry and Neuropsychopharmacology, Taipei, Sep. 2014.
15. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Kazutaka Ohi, Ryota Hashimoto, Shinji Shimodera, Issei Imoto, Masatoshi Takeda and Tetsuro Ohmori :
The effect of MTHFR C677T on DNA methylation of peripheral leukocytes in schizophrenia.,
Neuroscience, San Diego, Nov. 2013.
16. Akira Nishi, Shusuke Numata, Atsushi Tajima, Kumiko Kikuchi, Makoto Kinoshita, Shinji Shimodera, Masahito Tomotake, Issei Imoto and Tetsuro Ohmori :
Total plasma homocysteine and schizophrenia: gender and MTHFR C677T genotypes.,
Neuroscience, San Diego, Nov. 2013.
17. Masahito Nakataki, Satsuki Sumitani, Hiroko Kubo, Shusuke Numata, Junichi Iga, Shinya Watanabe, Makoto Kinoshita, Masafumi Harada and Tetsuro Ohmori :
Structural brain asymmetry in obsessive-compulsive disorder.,
11th world congress of biological psychiatry, Kyoto, Jun. 2013.
18. Shinya Watanabe, Junichi Iga, Shusuke Numata, Makoto Kinoshita and Tetsuro Ohmori :
Biological diagnostic test for major depressive disorder based on the leukocytes gene expression: Preliminary study.,
11th world congress of biological psychiatry, Kyoto, Jun. 2013.
19. Shusuke Numata, Makoto Kinoshita, Atsushi Tajima, Shinji Shimodera, Junichi Iga, Shinya Watanabe, Issei Imoto and Tetsuro Ohmori :
Genome-wide methylation status of human leukocytes in mood disorders.,
11th world congress of biological psychiatry, Kyoto, Jun. 2013.
20. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Shinji Shimodera, Issei Imoto and Tetsuro Ohmori :
Genome-wide association study of plasma homocysteine and DNA methylation in patients with schizophrenia.,
11th world congress of biological psychiatry, Kyoto, Jun. 2013.
21. Shusuke Numata, Kumiko Kikuchi, Atsushi Tajima, Makoto Kinoshita, Shinji Shimodera, Masahito Tomotake, Issei Imoto and Tetsuro Ohmori :
Plasma homocysteine and schizophrenia: A gender-specific meta-analysis.,
11th world congress of biological psychiatry, Kyoto, Jun. 2013.
22. Shusuke Numata, Makoto Kinoshita, Atsushi Tajima, Shinji Shimodera, Junichi Iga, Shinya Watanabe, Issei Imoto and Tetsuro Ohmori :
Blood-based DNA methylation biomarkers for schizophrenia.,
Neuroscience, New Orleans, Oct. 2012.
23. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Shinya Watanabe, Junichi Iga, S Shinji, Issei Imoto and Tetsuro Ohmori :
Genome-wide DNA methylation analysis using peripheral blood samples derived from unmedicated patients with schizophrenia.,
28th CINP Congress, Stockholm, Jun. 2012.

Proceeding of Domestic Conference:

1. Makoto Kinoshita :
JSCNP海外研修員・ポールヤンセン賞winnerたちが切る,これからの精神薬理・学会,
第30回日本臨床精神神経薬理学会学術総会, Jan. 2021.
2. Makoto Kinoshita :
第9回若手研究者育成プログラムショートトーク,
第42回日本生物学的精神医学会, Aug. 2020.
3. Makoto Kinoshita, Shusuke Numata, 大沼 徹 and Tetsuro Ohmori :
双極性障害の末梢血を用いたDNAメチル化修飾解析研究,
第38回 躁うつ病の薬理・生化学的研究懇話会, Nov. 2019.
4. Makoto Kinoshita, Hidehiro Umehara, Shinya Watanabe, Masahito Nakataki, Atsushi Tajima, Shusuke Numata and Tetsuro Ohmori :
統合失調症における網羅的血漿ホモシステイン濃度関連遺伝子同定研究,
第41回日本生物学的精神医学会, Jun. 2019.
5. Makoto Kinoshita, Gözde Ayhan, Esin Candemir, Sarah Kittel-Schneider, Andreas Reif and Florian Freudenberg :
統合失調症の死後脳を用いた,グルタミン酸NOパスウェイに関連する遺伝子発現解析研究,
日本臨床精神神経薬理学会, Nov. 2018.
6. Masatoshi Inoshita, Hidehiro Umehara, Shinya Watanabe, Masahito Nakataki, Makoto Kinoshita, Yukiko Tomioka, Atsushi Tajima, Shusuke Numata and Tetsuro Ohmori :
うつ病患者の末梢血グルタミン酸濃度のメタ解析,
第15回日本うつ病学会総会, Jul. 2018.
7. Masashi Ohta, Masahito Nakataki, Tomoya Takeda, Shusuke Numata, Takeo Tominaga, Naomi Kameoka, Hiroko Kubo, Makoto Kinoshita, 松浦 可苗, Maki Ohtomo, 武市 直也, Masafumi Harada and Tetsuro Ohmori :
統合失調症におけるSalience Network機能障害,抑うつ気分,および主観的QOLの因果関係.,
第114回日本精神神経学会学術総会, Jun. 2018.
8. 西 晃, Shusuke Numata, Atsushi Tajima, Xiaolei Zhu, 伊藤 候輝, 斎藤 淳, Yusuke Kato, Makoto Kinoshita, 下寺 信次, 小野 慎治, 越智 紳一郎, 今村 明, 黒滝 直弘, Shu-ichi Ueno, 岩田 仲生, Kiyoshi Fukui, Issei Imoto, 神谷 篤 and Tetsuro Ohmori :
統合失調症におけるde novo変異(突然変異)研究,
第13回日本統合失調症学会, Mar. 2018.
9. Yukiko Tomioka, Shusuke Numata, Makoto Kinoshita, Hidehiro Umehara, Shinya Watanabe, Masahito Nakataki, 岩山 佳美, 豊田 倫子, 池田 匡志, 山森 英長, 下寺 信次, Atsushi Tajima, 橋本 亮太, 岩田 仲生, 吉川 武男 and Tetsuro Ohmori :
血清ピリドキサール(ビタミンB6)と統合失調症の関連研究,
第13回日本統合失調症学会, Mar. 2018.
10. Tomoya Takeda, Masahito Nakataki, Masashi Ohta, 濱谷 沙世, 松浦 可苗, 吉田 玲於奈, Naomi Kameoka, Takeo Tominaga, 坂本 新介, Hidehiro Umehara, Makoto Kinoshita, Hiroko Kubo, Shinya Watanabe, Shusuke Numata, Satsuki Sumitani and Tetsuro Ohmori :
統合失調症患者の否定的・肯定的自動思考と臨床要因との関連,
第13回統合失調症学会, Mar. 2018.
11. Hidehiro Umehara, Shinya Watanabe, Makoto Kinoshita, Yukiko Tomioka, Masahito Nakataki, 畠山 豊, 中原 潔, Takeshi Nikawa, Shusuke Numata and Tetsuro Ohmori :
うつ病における血漿グルタミン,グルタミン酸,グルタミン/グルタミン酸比,
第27回日本臨床精神神経薬理学会, Nov. 2017.
12. Masatoshi Inoshita, Makoto Kinoshita, Hidehiro Umehara, Masahito Nakataki, Atsushi Tajima, 池田 匡志, 丸山 惣一郎, 山森 英長, 金沢 徹文, 下寺 信次, 橋本 亮太, Issei Imoto, 米田 博, 岩田 仲生, Shusuke Numata and Tetsuro Ohmori :
C-reactive protein and schizophrenia; A Mendelian Randomization approach.,
第12回日本統合失調症学会, Mar. 2017.
13. Makoto Kinoshita, Shusuke Numata, Masatoshi Inoshita and Tetsuro Ohmori :
統合失調症における血漿CRP濃度のDNAメチル化修飾への影響検討研究,
第38回日本生物学的精神医学会, Sep. 2016.
14. Junichi Iga, Shinya Watanabe, Shusuke Numata, Hidehiro Umehara, Akira Nishi, Makoto Kinoshita, Masatoshi Inoshita, 下寺 信次, 藤田 博一 and Tetsuro Ohmori :
うつ病患者における5HTTLPR,DNAメチル化,遺伝子発現の関連研究,
第25回日本臨床精神薬理学会, Oct. 2015.
15. Masatoshi Inoshita, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, Hidehiro Umehara, 山森 英長, 橋本 亮太, Issei Imoto and Tetsuro Ohmori :
細胞異種性を考慮した末梢血白血球のDNAメチル化の性差の検討,
第37回日本生物学的精神医学会, Sep. 2015.
16. Shusuke Numata, Makoto Kinoshita and Tetsuro Ohmori :
One-Carbon Metabolismに着目した統合失調症の病態解明と治療法開発,
第111回日本精神神経学会学術総会, Jun. 2015.
17. Hidehiro Umehara, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, 仲秋 秀太郎, Issei Imoto, Satsuki Sumitani and Tetsuro Ohmori :
BDNF Val66Met多型と強迫性障害;メタ解析ならびに治療反応性,
第24回日本臨床精神神経薬理学会, Nov. 2014.
18. 藤田 美香, Makoto Kinoshita, Satsuki Sumitani and Tetsuro Ohmori :
初診時にけいれん発作を生じてんかんとの鑑別に苦慮した統合失調症の1例.,
第55回中国・四国精神神経学会., Oct. 2014.
19. Makoto Kinoshita :
ホモシステインに着目した統合失調症病態解析研究,
第36回日本生物学的精神医学会第57回日本神経化学会大会, Sep. 2014.
20. Hidehiro Umehara, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, 仲秋 秀太郎, Issei Imoto, Satsuki Sumitani and Tetsuro Ohmori :
COMT Val158Met多型と強迫性障害の遺伝子関連ならびにメタ解析研究,
第36回日本生物学的精神医学会, Sep. 2014.
21. 石井 一夫, Shusuke Numata, Makoto Kinoshita and Tetsuro Ohmori :
大規模データ分析による精神神経系疾患診断系の検討,
第13回情報科学技術フォーラム, Sep. 2014.
22. Makoto Kinoshita :
One-carbon metabolismに着目した統合失調症研究 (第16回日本精神神経学会精神医学奨励賞受賞講演),
第110回日本精神神経学会学術総会, Jun. 2014.
23. Makoto Kinoshita :
DNA methylation signatures of peripheral leukocytes in schizophrenia.Plasma total homocyteine is associated with DNA methylation in patients with schizophrenia.,
第110回日本精神神経学会学術総会, Jun. 2014.
24. Shusuke Numata, Makoto Kinoshita, 石井 一夫 and Tetsuro Ohmori :
統合失調症の診断バイオマーカーの探索,
第110回日本精神神経学会学術総会, Jun. 2014.
25. Shusuke Numata, Masatoshi Inoshita, Atsushi Tajima, Makoto Kinoshita, 下寺 信次, Issei Imoto and Tetsuro Ohmori :
CRPと統合失調症のメタ解析研究,
第110回日本精神神経学会学術総会, Jun. 2014.
26. 石井 一夫, Shusuke Numata, Makoto Kinoshita and Tetsuro Ohmori :
次世代シークエンサーによる精神神経系疾患診断系の検討,
2014年度日本計量生物学会年会, May 2014.
27. 石井 一夫, Shusuke Numata, Makoto Kinoshita, Junichi Iga, Shinya Watanabe and Tetsuro Ohmori :
ビックデータ処理による統計学的手法を用いた精神神経系疾患診断の検討,
応用統計学会2014年度会, May 2014.
28. 石井 一夫, Shusuke Numata, Makoto Kinoshita and Tetsuro Ohmori :
ビックデータ分析による精神神経系疾患診断系の検討,
日本計算機統計学会第28回大会, May 2014.
29. Makoto Kinoshita, Shusuke Numata, 土屋 篤司, Sho Muraki, Akira Nishi, Atsushi Tajima, Issei Imoto and Tetsuro Ohmori :
血漿ホモシステイン濃度に影響を与える機能性多型の統合失調症遺伝子関連研究,
第9回日本統合失調症学会, Mar. 2014.
30. 石井 一夫, Shusuke Numata, Makoto Kinoshita, Junichi Iga, Shinya Watanabe, 飯田 満 and Tetsuro Ohmori :
Amazon Cloud ビッグデータ解析環境による精神神経系疾患診断系の構築,
情報処理学会第76回全国大会, Mar. 2014.
31. Shusuke Numata, Makoto Kinoshita and Tetsuro Ohmori :
ゲノム・ワイドメチル化解析からみた統合失調症の病態,
第23回日本臨床精神神経薬理学会, Oct. 2013.
32. Shusuke Numata, Makoto Kinoshita, Atsushi Tajima, 下寺 信次, 橋本 亮太, Issei Imoto, 武田 雅俊 and Tetsuro Ohmori :
治療抵抗性統合失調症のバイオマーカー,
第23回日本臨床精神神経薬理学会, Oct. 2013.
33. Akira Nishi, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, Shinji Shimodera, Kazutaka Ohi, Ryota Hashimoto, Issei Imoto, Masatoshi Takeda and Tetsuro Ohmori :
Functional variants of the MTHFR gene and schizophrenia in the Japanese population.,
第36回日本神経科学大会, Jun. 2013.
34. Junichi Iga, Shinya Watanabe, Akira Nishi, Shusuke Numata, Makoto Kinoshita, Kumiko Kikuchi, Masahito Nakataki and Tetsuro Ohmori :
Microarray analysis of the leukocyte global gene expression profile following lithium treatment.,
Neuro 2013(第36回日本神経科学大会・第56回日本神経化学会大会・第23回日本神経回路学会大会, Jun. 2013.
35. Shusuke Numata, Makoto Kinoshita, Atsushi Tajima, 下寺 信次, 橋本 亮太, 武田 雅俊, Issei Imoto and Tetsuro Ohmori :
統合失調症における末梢血DNAメチル化修飾解析研究,
第8回日本統合失調症学会, Apr. 2013.
36. Junichi Iga, Shinya Watanabe, 西 晃, Shusuke Numata, Makoto Kinoshita, Masahito Nakataki and Tetsuro Ohmori :
白血球遺伝子発現を指標としたリチウムの精神薬理学的研究,
第22回日本臨床精神神経薬理学会, Oct. 2012.
37. Shusuke Numata, Makoto Kinoshita, Atsushi Tajima, 大井 一高, 橋本 亮太, 下寺 信次, Issei Imoto, 武田 雅俊 and Tetsuro Ohmori :
メタアナリシス解析を用いたDISC1機能多型と統合失調症の遺伝子関連研究,
第34回日本生物学的精神医学会, Sep. 2012.
38. Makoto Kinoshita, Masahito Nakataki, Satsuki Sumitani and Tetsuro Ohmori :
片側電極のOn-Offによって躁状態とうつ状態を呈した両側STN-DBSを施行されたパーキンソン病の一例,
第34回日本生物学的精神医学会, Sep. 2012.
39. Makoto Kinoshita, Masahito Nakataki, Satsuki Sumitani and Tetsuro Ohmori :
両側視床下核深部脳刺激術を施行され左側電極Onによってうつ状態から躁状態に転じたパーキンソン病の一例,
第52回中国・四国精神神経学会, Nov. 2011.

Et cetera, Workshop:

1. 武田 知也, Masahito Nakataki, Masashi Ohta, 濱谷 沙世, 松浦 可苗, 吉田 玲於奈, Naomi Kameoka, Takeo Tominaga, 坂本 新介, Hidehiro Umehara, Makoto Kinoshita, Hiroko Kubo, Shinya Watanabe, Shusuke Numata, Satsuki Sumitani and Tetsuro Ohmori :
統合失調症患者における神経認知機能と否定的・肯定的認知の関連.,
第4回CEPD会, Mar. 2018.
2. Hidehiro Umehara, Shinya Watanabe, Makoto Kinoshita, Yukiko Tomioka, Masahito Nakataki, 畠山 豊, 中原 潔, Takeshi Nikawa, Shusuke Numata and Tetsuro Ohmori :
うつ病のメタボローム解析,
第2回メタボローム解析シンポジウム, Jun. 2017.
3. Makoto Kinoshita, Shusuke Numata, Yukiko Tomioka, 吉田 冬子, 功刀 浩 and Tetsuro Ohmori :
Evaluation of causal associations between C-reactive protein levels and bipolar disorder.,
第35回躁うつ病の薬理・生化学的研究懇話会, Nov. 2016.
4. Shusuke Numata, Masatoshi Inoshita, Makoto Kinoshita, 石井 一夫 and Tetsuro Ohmori :
DNAメチル化修飾を利用した双極性障害のバイオマーカーの検討,
第47回精神神経系薬物治療研究報告会, Dec. 2014.
5. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Akira Nishi, Sho Muraki, Atsushi Tsuchiya, Issei Imoto and Tetsuro Ohmori :
MTHFR遺伝子の機能性多型と統合失調症の遺伝子関連研究,
平成25年度脳クラスターミニリトリート, Feb. 2014.
6. Masatoshi Inoshita, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, 下寺 信次, Issei Imoto and Tetsuro Ohmori :
C-reactive protein と統合失調症との関連研究,
平成25年度脳クラスターミニリトリート, Feb. 2014.
7. Shusuke Numata, Makoto Kinoshita, Atsushi Tajima, 下寺 信次, Issei Imoto and Tetsuro Ohmori :
One-carbon metabolismに注目した統合失調症のメチル化解析研究,
第46回精神神経系薬物治療研究会報告会, Dec. 2013.
8. Shusuke Numata, Makoto Kinoshita, Atsushi Tajima, Junichi Iga, 下寺 信次, 橋本 亮太, Issei Imoto, 武田 雅俊 and Tetsuro Ohmori :
DNAメチル化修飾に着目したクロザピンの薬理作用解明と臨床反応予測の検討,
第46回精神神経系薬物治療研究会報告会, Dec. 2013.
9. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Issei Imoto and Tetsuro Ohmori :
統合失調症における血漿ホモシステインとDNAメチル化の関連解析,
2013 脳科学クラスター・ミニリトリート, Feb. 2013.
10. Akira Nishi, Shusuke Numata, Atsushi Tajima, Makoto Kinoshita, Issei Imoto and Tetsuro Ohmori :
MTHFR遺伝子と統合失調症の遺伝子関連解析,
平成24年度ストレスと栄養クラスター研究報告会, Jan. 2013.
11. Shinya Watanabe, Junichi Iga, Shusuke Numata, Makoto Kinoshita and Tetsuro Ohmori :
末梢血白血球の遺伝子発現パターンを利用した大うつ病の診断バイオマーカーに関する検討,
第45回記念 精神神経系薬物治療研究会報告会, Dec. 2012.
12. Shusuke Numata, Makoto Kinoshita, Atsushi Tajima, 下寺 信次, Issei Imoto and Tetsuro Ohmori :
DNAメチル化修飾解析研究:死後脳と末梢血の相違,
第31回躁うつ病の薬理・生化学的研究懇話会, Nov. 2012.
13. Makoto Kinoshita, Shusuke Numata, Atsushi Tajima, Issei Imoto and Tetsuro Ohmori :
統合失調症の末梢血を用いた網羅的DNAメチル化修飾解析研究,
平成23年度ストレスと栄養クラスターリトリート, Jan. 2012.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)