=== Generating (published_papers) === === Generating (research_interests) === === Generating (education) === === Generating (research_experience) === === Generating (misc) === === Generating (research_projects) === === Generating (books_etc) === === Generating (industrial_property_rights) === === Generating (awards) === === Generating (association_memberships) === === Generating (teaching_experience) === === Generating (works) === === Generating (committee_memberships) === === Generating (presentations) === ==== begin registerFile(/WWW/pub2/data/ERD/person/248921/researchmap/published_papers.jsonl) ==== line:1, {"insert":{"user_id":"B000340651","type":"published_papers","id":"44462865"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=404649","label":"url"}],"paper_title":{"en":"Effect of soft denture liners on complete denture treatments: A systematic review","ja":"Effect of soft denture liners on complete denture treatments: A systematic review"},"authors":{"en":[{"name":"Hasegawa Y"},{"name":"Minakuchi H"},{"name":"Nishimura M"},{"name":"Nishio K"},{"name":"Yoshioka F"},{"name":"Ishii T"},{"name":"Watanabe T"},{"name":"Nishiyama Y"},{"name":"Sato Y"},{"name":"Yoshida K"},{"name":"Ma TSM"},{"name":"Iinuma T"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Hasegawa Y"},{"name":"Minakuchi H"},{"name":"Nishimura M"},{"name":"Nishio K"},{"name":"Yoshioka F"},{"name":"Ishii T"},{"name":"Watanabe T"},{"name":"Nishiyama Y"},{"name":"Sato Y"},{"name":"Yoshida K"},{"name":"Ma TSM"},{"name":"Iinuma T"},{"name":"松香 芳三"}]},"publication_date":"2024","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"number":"No.(in press)","languages":["eng"],"referee":true,"identifiers":{"issn":["1883-1958"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:2, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018844"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=386747","label":"url"}],"paper_title":{"en":"咬合違和感症候群の診療フローチャートの提案","ja":"咬合違和感症候群の診療フローチャートの提案"},"authors":{"en":[{"name":"和気 裕之"},{"name":"石垣 尚一"},{"name":"澁谷 智明"},{"name":"島田 淳"},{"name":"玉置 勝司"},{"name":"Matsuka Yoshizo"},{"name":"山口 泰彦"},{"name":"依田 哲也"},{"name":"和気 創"}],"ja":[{"name":"和気 裕之"},{"name":"石垣 尚一"},{"name":"澁谷 智明"},{"name":"島田 淳"},{"name":"玉置 勝司"},{"name":"松香 芳三"},{"name":"山口 泰彦"},{"name":"依田 哲也"},{"name":"和気 創"}]},"publication_date":"2024","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.in press","languages":["jpn"],"referee":true,"identifiers":{"issn":["0915-3004"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:3, {"insert":{"user_id":"B000340651","type":"published_papers","id":"45575843"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/119296","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=405053","label":"url"}],"paper_title":{"en":"Essence of diagnosis and management of sleep bruxism","ja":"Essence of diagnosis and management of sleep bruxism"},"authors":{"en":[{"name":"Suzuki Yoshitaka"},{"name":"Okura Kazuo"},{"name":"Tajima Toyoko"},{"name":"Dalanon Junhel"},{"name":"Ohshima Masamitsu"},{"name":"Hosoki Maki"},{"name":"Inoue Miho"},{"name":"Miyagi Mayu"},{"name":"Ikutame Daisuke"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"鈴木 善貴"},{"name":"大倉 一夫"},{"name":"田島 登誉子"},{"name":"Dalanon Junhel Casinillo"},{"name":"大島 正充"},{"name":"細木 眞紀"},{"name":"井上 美穂"},{"name":"宮城 麻友"},{"name":"生田目 大介"},{"name":"松香 芳三"}]},"publication_date":"2024-03-27","publication_name":{"en":"Journal of Oral Health and Biosciences","ja":"Journal of Oral Health and Biosciences"},"volume":"Vol.36","number":"No.2","starting_page":"22","ending_page":"29","languages":["eng"],"referee":true,"identifiers":{"issn":["2188-7888"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:4, {"insert":{"user_id":"B000340651","type":"published_papers","id":"44042727"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=404022","label":"url"}],"paper_title":{"en":"超高齢者における顎関節症症状とオーラルフレイル・フレイルとの関連","ja":"超高齢者における顎関節症症状とオーラルフレイル・フレイルとの関連"},"authors":{"en":[{"name":"水口 一"},{"name":"Koyama Kyoh"},{"name":"吉川 峰加"},{"name":"平岡 綾"},{"name":"吉田 光由"},{"name":"西山 暁"},{"name":"津賀 一弘"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"水口 一"},{"name":"小山 響央"},{"name":"吉川 峰加"},{"name":"平岡 綾"},{"name":"吉田 光由"},{"name":"西山 暁"},{"name":"津賀 一弘"},{"name":"松香 芳三"}]},"publication_date":"2024","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.in press","languages":["jpn"],"referee":true,"identifiers":{"issn":["0915-3004"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:5, {"insert":{"user_id":"B000340651","type":"published_papers","id":"41918401"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=395048","label":"url"}],"paper_title":{"en":"Risk of an immediate-type allergy to minocycline hydrochloride ointment","ja":"Risk of an immediate-type allergy to minocycline hydrochloride ointment"},"authors":{"en":[{"name":"Hosoki Maki"},{"name":"Okamoto Yoshifumi"},{"name":"Tajima Toyoko"},{"name":"Miyagi Mayu"},{"name":"Kubo Yoshiaki"},{"name":"Sogawa Maiko"},{"name":"Raju R"},{"name":"Afroz S"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"細木 眞紀"},{"name":"Okamoto Yoshifumi"},{"name":"田島 登誉子"},{"name":"宮城 麻友"},{"name":"久保 宜明"},{"name":"Sogawa Maiko"},{"name":"RESMI RAJU"},{"name":"SHAISTA AFROZ"},{"name":"松香 芳三"}]},"publication_date":"2023-12","publication_name":{"en":"Operative Dentistry, Endodontology and Periodontology","ja":"Operative Dentistry, Endodontology and Periodontology"},"volume":"Vol.3","number":"No.1","starting_page":"152","ending_page":"157","languages":["eng"],"referee":true,"identifiers":{"doi":["10.11471/odep.2023-018"],"issn":["2436-4975"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:6, {"insert":{"user_id":"B000340651","type":"published_papers","id":"40552673"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36484175","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=392929","label":"url"}],"paper_title":{"en":"Job shadowing for early undergraduate dental students: Validation of educational effectiveness using structural equation modeling","ja":"Job shadowing for early undergraduate dental students: Validation of educational effectiveness using structural equation modeling"},"authors":{"en":[{"name":"Abe Susumu"},{"name":"Matsuka Yoshizo"},{"name":"Murakami Ayu"},{"name":"Rodis Omar"},{"name":"Oka Kenji"},{"name":"Okawa Toshinori"},{"name":"Wada -Mihara Chie"},{"name":"Shinohara Chihiro"},{"name":"Kawano Fumiaki"}],"ja":[{"name":"安陪 晋"},{"name":"松香 芳三"},{"name":"Murakami Ayu"},{"name":"ロディス オマー"},{"name":"岡 謙次"},{"name":"大川 敏永"},{"name":"美原(和田) 智恵"},{"name":"篠原 千尋"},{"name":"河野 文昭"}]},"description":{"en":"This study aimed to evaluate and validate the educational effectiveness of a job shadowing class as a dental teaching programme for preclinical dental students through a questionnaire that assessed related student perceptions. A total of 124 preclinical (second year) dental students at Tokushima University participated in job shadowing placements from 2017 to 2019. Each student observed dental practice or surgery for 1 day in the university hospital. After shadowing, the students were requested to fill out a nine-item questionnaire based on a five-point scale. The first analysis was performed to calculate the correlation for each item. Furthermore, regression analysis for the categorical data was performed to show the relationship between eight questions (Items 1-8) and one question (Item 9: comprehensive evaluation). Next, factor analysis was performed to determine students' perceptions regarding the shadowing class. Ninety-eight students (response rate: 79%) completed the questionnaire. There was a strong relationship amongst Items 1, 8 and 9 (\"interested in dentistry as a job,\" \"learning motivation\" and \"comprehensive evaluation\" respectively) based on the results of the correlation and regression analysis. The factor analysis led to three student perceptions as latent factors, namely, \"Interesting,\" \"Self-awareness\" and \"Future Goal,\" which had a relatively close inter-factor correlation (0.465-0.772). The finding suggests that job shadowing may increase a students' interest in a dentistry career at an early stage of their education and learning motivation, along with generating self-awareness. This programme may present possible educational effectiveness in dental education.","ja":"This study aimed to evaluate and validate the educational effectiveness of a job shadowing class as a dental teaching programme for preclinical dental students through a questionnaire that assessed related student perceptions. A total of 124 preclinical (second year) dental students at Tokushima University participated in job shadowing placements from 2017 to 2019. Each student observed dental practice or surgery for 1 day in the university hospital. After shadowing, the students were requested to fill out a nine-item questionnaire based on a five-point scale. The first analysis was performed to calculate the correlation for each item. Furthermore, regression analysis for the categorical data was performed to show the relationship between eight questions (Items 1-8) and one question (Item 9: comprehensive evaluation). Next, factor analysis was performed to determine students' perceptions regarding the shadowing class. Ninety-eight students (response rate: 79%) completed the questionnaire. There was a strong relationship amongst Items 1, 8 and 9 (\"interested in dentistry as a job,\" \"learning motivation\" and \"comprehensive evaluation\" respectively) based on the results of the correlation and regression analysis. The factor analysis led to three student perceptions as latent factors, namely, \"Interesting,\" \"Self-awareness\" and \"Future Goal,\" which had a relatively close inter-factor correlation (0.465-0.772). The finding suggests that job shadowing may increase a students' interest in a dentistry career at an early stage of their education and learning motivation, along with generating self-awareness. This programme may present possible educational effectiveness in dental education."},"publication_date":"2023-11","publication_name":{"en":"European Journal of Dental Education","ja":"European Journal of Dental Education"},"volume":"Vol.27","number":"No.4","starting_page":"898","ending_page":"907","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/eje.12880"],"issn":["1600-0579"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:7, {"insert":{"user_id":"B000340651","type":"published_papers","id":"40607583"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36740263","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=393367","label":"url"}],"paper_title":{"en":"Mechanism and clinical use of botulinum neurotoxin in head and facial region","ja":"Mechanism and clinical use of botulinum neurotoxin in head and facial region"},"authors":{"en":[{"name":"Raman Swarnalakshmi"},{"name":"Yamamoto Yumiko"},{"name":"Suzuki Yoshitaka"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"RAMAN SWARNA LAKSHMI"},{"name":"Yamamoto Yumiko"},{"name":"鈴木 善貴"},{"name":"松香 芳三"}]},"description":{"en":"Botulinum neurotoxin (BoNT) is a biological toxin produced by Clostridium botulinum. BoNT is a potent toxin extensively used in therapeutic interventions. This review provides an updated overview of the mechanisms of action and clinical applications of BoNT in head and facial region. MEDLINE/PubMed searches were conducted using the terms \"botulinum neurotoxin\" and \"dentistry\" along with a combination of other related terms. In addition, studies were manually selected from reference lists of the selected articles. The Food and Drug Administration in the United States initially approved BoNT to treat strabismus, blepharospasm, and hemifacial spasms. The use of BoNT in dermatology and cosmetics has been widely established and has created a revolution in these fields. Over the years, its applications in various medical specialties have expanded widely. Owing to its safety, efficacy, and long duration of action, it is well-accepted by patients. BoNT/A and BoNT/B are widely used in clinical practice. Several off-label uses of BoNT in the dental fraternity have yielded promising results. We have elaborated on the speculated mechanism of action, dosage, effective sites of injection, and adverse effects of each therapeutic application. The various clinical indications for BoNT include bruxism, myofascial pain, temporomandibular joint dislocation, hemifacial pain, orofacial dystonia, facial paralysis, chronic migraine, and trigeminal neuralgia. BoNT is a safe treatment that can be used effectively, provided that the clinician has adequate knowledge regarding the mechanism, injection techniques, and local and systemic side effects and that it is administered cautiously and purposefully.","ja":"Botulinum neurotoxin (BoNT) is a biological toxin produced by Clostridium botulinum. BoNT is a potent toxin extensively used in therapeutic interventions. This review provides an updated overview of the mechanisms of action and clinical applications of BoNT in head and facial region. MEDLINE/PubMed searches were conducted using the terms \"botulinum neurotoxin\" and \"dentistry\" along with a combination of other related terms. In addition, studies were manually selected from reference lists of the selected articles. The Food and Drug Administration in the United States initially approved BoNT to treat strabismus, blepharospasm, and hemifacial spasms. The use of BoNT in dermatology and cosmetics has been widely established and has created a revolution in these fields. Over the years, its applications in various medical specialties have expanded widely. Owing to its safety, efficacy, and long duration of action, it is well-accepted by patients. BoNT/A and BoNT/B are widely used in clinical practice. Several off-label uses of BoNT in the dental fraternity have yielded promising results. We have elaborated on the speculated mechanism of action, dosage, effective sites of injection, and adverse effects of each therapeutic application. The various clinical indications for BoNT include bruxism, myofascial pain, temporomandibular joint dislocation, hemifacial pain, orofacial dystonia, facial paralysis, chronic migraine, and trigeminal neuralgia. BoNT is a safe treatment that can be used effectively, provided that the clinician has adequate knowledge regarding the mechanism, injection techniques, and local and systemic side effects and that it is administered cautiously and purposefully."},"publication_date":"2023-09-01","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.67","number":"No.4","starting_page":"493","ending_page":"505","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2186/jpr.JPR_D_22_00238"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:8, {"insert":{"user_id":"B000340651","type":"published_papers","id":"41168633"},"force":{"see_also":[{"@id":"https://www.jstage.jst.go.jp/article/sgf/29/2/29_75/_pdf","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390298211935446656/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=393668","label":"url"}],"paper_title":{"en":"First Step to Understand Jaw Movement -For the CAD/CAM Era-","ja":"顎運動を攻略するための第一歩 CAD/CAM 時代に向けて―"},"authors":{"en":[{"name":"Bando Eiichi"},{"name":"Suzuki Yoshitaka"},{"name":"Fujimura Tetsuya"},{"name":"Tajima Toyoko"},{"name":"Okura Kazuo"},{"name":"Yoshihara Yasutomo"},{"name":"Ozawa Aya"},{"name":"Shinkai Mizuki"},{"name":"Taniwaki Tatsuya"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"坂東 永一"},{"name":"鈴木 善貴"},{"name":"藤村 哲也"},{"name":"田島 登誉子"},{"name":"大倉 一夫"},{"name":"吉原 靖智"},{"name":"小澤 彩"},{"name":"新開 瑞希"},{"name":"谷脇 竜弥"},{"name":"松香 芳三"}]},"publication_date":"2023-03","publication_name":{"en":"The Journal of Japanese Society of Stomatognathic Function","ja":"日本顎口腔機能学会雑誌"},"volume":"Vol.29","number":"No.2","starting_page":"75","ending_page":"90","languages":["jpn"],"referee":true,"invited":true,"identifiers":{"doi":["10.7144/sgf.29.75"],"issn":["1340-9085"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:9, {"insert":{"user_id":"B000340651","type":"published_papers","id":"41802431"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/118082","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36983746","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=394609","label":"url"}],"paper_title":{"en":"Targeted therapy for orofacial pain: A novel perspective for precision medicine","ja":"Targeted therapy for orofacial pain: A novel perspective for precision medicine"},"authors":{"en":[{"name":"Raman S"},{"name":"Ikutame Daisuke"},{"name":"Okura Kazuo"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"RAMAN SWARNA LAKSHMI"},{"name":"生田目 大介"},{"name":"大倉 一夫"},{"name":"松香 芳三"}]},"description":{"en":"Orofacial pain (OFP) is a dental specialty that includes the diagnosis, management and treatment of disorders of the jaw, mouth, face, head and neck. Evidence-based understanding is critical in effectively treating OFPs as the pathophysiology of these conditions is multifactorial. Since OFP impacts the quality of life of the affected individuals, treating patients successfully is of the utmost significance. Despite the therapeutic choices available, treating OFP is still quite challenging, owing to inter-patient variations. The emerging trends in precision medicine could probably lead us to a paradigm shift in effectively managing the untreatable long-standing pain conditions. Precision medicine is designed based on the patient's genetic profile to meet their needs. Several significant relationships have been discovered based on the genetics and genomics of pain in the past, and some of the notable targets are discussed in this review. The scope of this review is to discuss preclinical and clinical trials that include approaches used in targeted therapy for orofacial pain. Future developments in pain medicine should benefit from current trends in research into novel therapeutic approaches.","ja":"Orofacial pain (OFP) is a dental specialty that includes the diagnosis, management and treatment of disorders of the jaw, mouth, face, head and neck. Evidence-based understanding is critical in effectively treating OFPs as the pathophysiology of these conditions is multifactorial. Since OFP impacts the quality of life of the affected individuals, treating patients successfully is of the utmost significance. Despite the therapeutic choices available, treating OFP is still quite challenging, owing to inter-patient variations. The emerging trends in precision medicine could probably lead us to a paradigm shift in effectively managing the untreatable long-standing pain conditions. Precision medicine is designed based on the patient's genetic profile to meet their needs. Several significant relationships have been discovered based on the genetics and genomics of pain in the past, and some of the notable targets are discussed in this review. The scope of this review is to discuss preclinical and clinical trials that include approaches used in targeted therapy for orofacial pain. Future developments in pain medicine should benefit from current trends in research into novel therapeutic approaches."},"publication_date":"2023-03-22","publication_name":{"en":"Journal of Personalized Medicine","ja":"Journal of Personalized Medicine"},"volume":"Vol.13","number":"No.3","starting_page":"565","ending_page":"565","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/jpm13030565"],"issn":["2075-4426"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:10, {"insert":{"user_id":"B000340651","type":"published_papers","id":"41092320"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/117923","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36830814","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=393553","label":"url"}],"paper_title":{"en":"Identification of microRNA signatures in peripheral blood of young women as potential biomarkers for metal allergy","ja":"Identification of microRNA signatures in peripheral blood of young women as potential biomarkers for metal allergy"},"authors":{"en":[{"name":"Zhang Yuehui"},{"name":"Hosoki Maki"},{"name":"Ohshima Masamitsu"},{"name":"Tajima Toyoko"},{"name":"Miyagi Mayu"},{"name":"Raman S"},{"name":"Raju R"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"ZHANG YUEHUI"},{"name":"細木 眞紀"},{"name":"大島 正充"},{"name":"田島 登誉子"},{"name":"宮城 麻友"},{"name":"RAMAN SWARNA LAKSHMI"},{"name":"RESMI RAJU"},{"name":"松香 芳三"}]},"description":{"en":"MicroRNA (miRNA) is a short (19-24 nucleotide) endogenous non-protein RNA that exists in the body and controls the translation process from genes to proteins. It has become useful as a diagnostic tool and a potential treatment target in cancer research. To explore the function of miRNA in contact dermatitis, female participants with a positive metal allergy diagnosis ( = 3) were enrolled along with additional female participants with no medical history of metal allergy ( = 3). A patch test was performed on each participant. Peripheral blood was collected from all the participants before the patch test and at days 3 and 7 after starting the patch test. After total RNA was obtained from peripheral blood leukocytes and cDNA was generated, microarray analysis was performed to analyze the large-scale circulating miRNA profile. Real-time polymerase chain reaction (RT-PCR) was then used to clarify the overall target miRNA expression. Downregulation of hsa-let-7d-5p, hsa-miR-24-3p, hsa-miR-23b-3p, hsa-miR-26b-5p, and hsa-miR-150-5p was found on day 7. Certain miRNAs were confirmed using RT-PCR. These peripheral blood miRNAs could be diagnostic biomarkers for metal allergies.","ja":"MicroRNA (miRNA) is a short (19-24 nucleotide) endogenous non-protein RNA that exists in the body and controls the translation process from genes to proteins. It has become useful as a diagnostic tool and a potential treatment target in cancer research. To explore the function of miRNA in contact dermatitis, female participants with a positive metal allergy diagnosis ( = 3) were enrolled along with additional female participants with no medical history of metal allergy ( = 3). A patch test was performed on each participant. Peripheral blood was collected from all the participants before the patch test and at days 3 and 7 after starting the patch test. After total RNA was obtained from peripheral blood leukocytes and cDNA was generated, microarray analysis was performed to analyze the large-scale circulating miRNA profile. Real-time polymerase chain reaction (RT-PCR) was then used to clarify the overall target miRNA expression. Downregulation of hsa-let-7d-5p, hsa-miR-24-3p, hsa-miR-23b-3p, hsa-miR-26b-5p, and hsa-miR-150-5p was found on day 7. Certain miRNAs were confirmed using RT-PCR. These peripheral blood miRNAs could be diagnostic biomarkers for metal allergies."},"publication_date":"2023-01-19","publication_name":{"en":"Biomedicines","ja":"Biomedicines"},"volume":"Vol.11","number":"No.2","starting_page":"277","ending_page":"277","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/biomedicines11020277"],"issn":["2227-9059"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:11, {"insert":{"user_id":"B000340651","type":"published_papers","id":"41974018"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=395130","label":"url"}],"paper_title":{"en":"歯科心身症の概要と新概念への展望","ja":"歯科心身症の概要と新概念への展望"},"authors":{"en":[{"name":"和気 裕之"},{"name":"澁谷 智明"},{"name":"石垣 尚一"},{"name":"依田 哲也"},{"name":"小見山 道"},{"name":"山口 泰彦"},{"name":"佐々木 啓一"},{"name":"Matsuka Yoshizo"},{"name":"築山 能大"},{"name":"角 忠輝"},{"name":"岡安 一郎"},{"name":"島田 淳"},{"name":"玉置 勝司"},{"name":"宮岡 等"},{"name":"窪木 拓男"},{"name":"宮地 英雄"},{"name":"菅沼 岳史"}],"ja":[{"name":"和気 裕之"},{"name":"澁谷 智明"},{"name":"石垣 尚一"},{"name":"依田 哲也"},{"name":"小見山 道"},{"name":"山口 泰彦"},{"name":"佐々木 啓一"},{"name":"松香 芳三"},{"name":"築山 能大"},{"name":"角 忠輝"},{"name":"岡安 一郎"},{"name":"島田 淳"},{"name":"玉置 勝司"},{"name":"宮岡 等"},{"name":"窪木 拓男"},{"name":"宮地 英雄"},{"name":"菅沼 岳史"}]},"publication_date":"2022-12","publication_name":{"en":"Japanese Journal of Orofacial Pain","ja":"日本口腔顔面痛学会雑誌"},"volume":"Vol.15","number":"No.1","starting_page":"1","ending_page":"11","languages":["jpn"],"referee":true,"identifiers":{"issn":["1883-308X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:12, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018846"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=385735","label":"url"}],"paper_title":{"en":"Survey of oral maxillofacial injury experiences and sports mouthguard use in wakeboarders","ja":"Survey of oral maxillofacial injury experiences and sports mouthguard use in wakeboarders"},"authors":{"en":[{"name":"Suzuki Yoshitaka"},{"name":"Okura Kazuo"},{"name":"Yoshihara Yasutomo"},{"name":"Dalanon Junhel"},{"name":"Akita Kazuya"},{"name":"Miyamoto Youji"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"鈴木 善貴"},{"name":"大倉 一夫"},{"name":"吉原 靖智"},{"name":"Dalanon Junhel Casinillo"},{"name":"秋田 和也"},{"name":"宮本 洋二"},{"name":"松香 芳三"}]},"publication_date":"2022-11-10","publication_name":{"en":"International Journal of Sports Dentistry","ja":"International Journal of Sports Dentistry"},"volume":"Vol.15","number":"No.1","starting_page":"17","ending_page":"24","languages":["eng"],"referee":true,"identifiers":{"issn":["1883-2865"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:13, {"insert":{"user_id":"B000340651","type":"published_papers","id":"40333699"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/118895","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36362625","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=392602","label":"url"}],"paper_title":{"en":"Relationship between oral parafunctional and postural habits and the symptoms of temporomandibular disorders: A survey-based cross-sectional cohort study using propensity score matching analysis","ja":"Relationship between oral parafunctional and postural habits and the symptoms of temporomandibular disorders: A survey-based cross-sectional cohort study using propensity score matching analysis"},"authors":{"en":[{"name":"Abe Susumu"},{"name":"Kawano Fumiaki"},{"name":"Matsuka Yoshizo"},{"name":"Masuda Taeko"},{"name":"Okawa Toshinori"},{"name":"Tanaka Eiji"}],"ja":[{"name":"安陪 晋"},{"name":"河野 文昭"},{"name":"松香 芳三"},{"name":"Masuda Taeko"},{"name":"大川 敏永"},{"name":"田中 栄二"}]},"description":{"en":"Temporomandibular disorders (TMDs) are a multifactorial joint disease of the masticatory system. The possible etiological factors involved in the onset and progression of TMDs include oral parafunctional habits (OPFHs) and postural habits (PHs). However, little information is available on the association between OPFHs and PHs and a predisposition to TMDs. Thus, to investigate whether the presence of OPFH and PH predisposes individuals to TMDs, a survey-based cross-sectional cohort study of self-reported TMD was performed. A total of 2292 patients with TMD were recruited for the survey. Through one-to-one propensity score matching, 166 patients with and without sleep bruxism (SB) were selected. The SB group had a significantly higher risk of masticatory muscular pain or fatigue than the non-SB group ( = 0.018). Furthermore, the SB group without other OFPHs and PHs did not show a significantly higher risk of TMD symptoms than the non-SB group. Diurnal clenching and bad posture also affect the stomatognathic system, causing pain or fatigue; however, it did not result in TMDs in patients without any OPFHs and PHs. This implies that OPFHs and PHs may increase the risk of TMD symptoms in coexistence with other habits.","ja":"Temporomandibular disorders (TMDs) are a multifactorial joint disease of the masticatory system. The possible etiological factors involved in the onset and progression of TMDs include oral parafunctional habits (OPFHs) and postural habits (PHs). However, little information is available on the association between OPFHs and PHs and a predisposition to TMDs. Thus, to investigate whether the presence of OPFH and PH predisposes individuals to TMDs, a survey-based cross-sectional cohort study of self-reported TMD was performed. A total of 2292 patients with TMD were recruited for the survey. Through one-to-one propensity score matching, 166 patients with and without sleep bruxism (SB) were selected. The SB group had a significantly higher risk of masticatory muscular pain or fatigue than the non-SB group ( = 0.018). Furthermore, the SB group without other OFPHs and PHs did not show a significantly higher risk of TMD symptoms than the non-SB group. Diurnal clenching and bad posture also affect the stomatognathic system, causing pain or fatigue; however, it did not result in TMDs in patients without any OPFHs and PHs. This implies that OPFHs and PHs may increase the risk of TMD symptoms in coexistence with other habits."},"publication_date":"2022-10-28","publication_name":{"en":"Journal of Clinical Medicine","ja":"Journal of Clinical Medicine"},"volume":"Vol.11","number":"No.21","starting_page":"6396","ending_page":"6396","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/jcm11216396"],"issn":["2077-0383"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:14, {"insert":{"user_id":"B000340651","type":"published_papers","id":"40333700"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36365931","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=392601","label":"url"}],"paper_title":{"en":"Physical load while using a tablet at different tilt angles during sitting and standing","ja":"Physical load while using a tablet at different tilt angles during sitting and standing"},"authors":{"en":[{"name":"Tomita Yosuke"},{"name":"Suzuki Yoshitaka"},{"name":"Shibagaki A"},{"name":"Takahashi Shingo"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Tomita Yosuke"},{"name":"鈴木 善貴"},{"name":"柴垣 あかり"},{"name":"Takahashi Shingo"},{"name":"松香 芳三"}]},"description":{"en":"Few standards and guidelines to prevent health problems have been associated with tablet use. We estimated the effects of posture and tablet tilt angle on muscle activity and posture in healthy young adults. Seventeen healthy young adults (age: 20.5 ± 3 years) performed a cognitive task using a tablet in two posture (sitting and standing) and tablet tilt angle (0 degrees and 45 deg) conditions. Segment and joint kinematics were evaluated using 16 inertial measurement unit sensors. Neck, trunk, and upper limb electromyography (EMG) activities were monitored using 12 EMG sensors. Perceived discomfort, kinematics, and EMG activities were compared between conditions using the Friedman test. The perceived discomfort in the standing-0 deg condition was significantly higher than in the remaining three conditions. Standing posture and tablet inclination significantly reduced the sagittal segment and joint angles of the spine, compared with sitting and flat tablet conditions. Similarly, standing posture and tablet inclination significantly reduced EMG activities of the dorsal neck, upper, and lower trunk muscles, while increasing EMG activity of shoulder flexors. Standing posture and tablet inclination reduced the sagittal flexion angle, and dorsal neck, upper, and lower trunk muscle activities, while potentially increasing the muscle activity of arm flexors.","ja":"Few standards and guidelines to prevent health problems have been associated with tablet use. We estimated the effects of posture and tablet tilt angle on muscle activity and posture in healthy young adults. Seventeen healthy young adults (age: 20.5 ± 3 years) performed a cognitive task using a tablet in two posture (sitting and standing) and tablet tilt angle (0 degrees and 45 deg) conditions. Segment and joint kinematics were evaluated using 16 inertial measurement unit sensors. Neck, trunk, and upper limb electromyography (EMG) activities were monitored using 12 EMG sensors. Perceived discomfort, kinematics, and EMG activities were compared between conditions using the Friedman test. The perceived discomfort in the standing-0 deg condition was significantly higher than in the remaining three conditions. Standing posture and tablet inclination significantly reduced the sagittal segment and joint angles of the spine, compared with sitting and flat tablet conditions. Similarly, standing posture and tablet inclination significantly reduced EMG activities of the dorsal neck, upper, and lower trunk muscles, while increasing EMG activity of shoulder flexors. Standing posture and tablet inclination reduced the sagittal flexion angle, and dorsal neck, upper, and lower trunk muscle activities, while potentially increasing the muscle activity of arm flexors."},"publication_date":"2022-10-27","publication_name":{"en":"Sensors","ja":"Sensors"},"volume":"Vol.22","number":"No.21","starting_page":"8237","ending_page":"8237","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/s22218237"],"issn":["1424-8220"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:15, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39569268"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/117804","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/35985779","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=388341","label":"url"}],"paper_title":{"en":"Therapy outcome measures in temporomandibular joint disorder: A scoping review","ja":"Therapy outcome measures in temporomandibular joint disorder: A scoping review"},"authors":{"en":[{"name":"Ooi Kazuhrio"},{"name":"Aihara Morio"},{"name":"Matsumura Hidehisa"},{"name":"Matsuda Shinpei"},{"name":"Watanabe Yuki"},{"name":"Yuasa Hidemich"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Ooi Kazuhrio"},{"name":"Aihara Morio"},{"name":"Matsumura Hidehisa"},{"name":"Matsuda Shinpei"},{"name":"Watanabe Yuki"},{"name":"Yuasa Hidemich"},{"name":"松香 芳三"}]},"description":{"en":"Therapy outcome measures (TOMs) in temporomandibular disorders (TMDs) have not been systematically evaluated. We systematically explored the main TOM assessment methods for TMD TOMs used in previous studies. Scoping review. According to Preferred Reporting Items for Systematic reviews and Meta-Analysis extension for Scoping Review reporting guidelines, we systematically searched five key databases (MEDLINE/PubMed, Web of Science, Embase, Epistemonikos and ClinicalTrials) and thoroughly scanned relevant grey literature using Medical Subject Headings, Emtree and index terms. We considered primary research papers published from January 2010 to December 2020 that included patients with TMD aged ≥18 years, diagnosed according to the Diagnostic Criteria for Temporomandibular Disorders. Four reviewers extracted general information and information on study design and setting, target, interventions, and outcome type. One hundred and seventy-two of the 3726 screened articles (3704 by search engines and 22 manually) were included. The TOMs analysed included pain (n=161 articles), maximal mouth opening (MMO) (91), jaw function (32), jaw movement (26), joint sound (16), quality of life (QOL) (15), depression/anxiety (14), oral QOL (10) or others (30). Evaluation periods were <4 weeks (111), <8 weeks (62), <12 weeks (59), >12 weeks (75) or 'not mentioned' (12). Pain outcomes (229) included general pain (115), tenderness (45), pain during functioning (44), resting pain (16) and others (8). Pain outcome evaluation methods included Visual Analogue Scale (VAS; 121), Numerical Rating Scale (21) and other methods (21). Pain outcome indicators were binary (10) or continuous (158); only five studies reported the least significant difference in treatment efficacy. MMO evaluation using painless methods (19) and jaw function evaluation using methods assessing mandibular movement range (23) were the most frequent. TMD TOMs are diverse; the major outcomes were pain, MMO, jaw function and jaw movement. Most pain outcomes are evaluated by VAS Score changes.","ja":"Therapy outcome measures (TOMs) in temporomandibular disorders (TMDs) have not been systematically evaluated. We systematically explored the main TOM assessment methods for TMD TOMs used in previous studies. Scoping review. According to Preferred Reporting Items for Systematic reviews and Meta-Analysis extension for Scoping Review reporting guidelines, we systematically searched five key databases (MEDLINE/PubMed, Web of Science, Embase, Epistemonikos and ClinicalTrials) and thoroughly scanned relevant grey literature using Medical Subject Headings, Emtree and index terms. We considered primary research papers published from January 2010 to December 2020 that included patients with TMD aged ≥18 years, diagnosed according to the Diagnostic Criteria for Temporomandibular Disorders. Four reviewers extracted general information and information on study design and setting, target, interventions, and outcome type. One hundred and seventy-two of the 3726 screened articles (3704 by search engines and 22 manually) were included. The TOMs analysed included pain (n=161 articles), maximal mouth opening (MMO) (91), jaw function (32), jaw movement (26), joint sound (16), quality of life (QOL) (15), depression/anxiety (14), oral QOL (10) or others (30). Evaluation periods were <4 weeks (111), <8 weeks (62), <12 weeks (59), >12 weeks (75) or 'not mentioned' (12). Pain outcomes (229) included general pain (115), tenderness (45), pain during functioning (44), resting pain (16) and others (8). Pain outcome evaluation methods included Visual Analogue Scale (VAS; 121), Numerical Rating Scale (21) and other methods (21). Pain outcome indicators were binary (10) or continuous (158); only five studies reported the least significant difference in treatment efficacy. MMO evaluation using painless methods (19) and jaw function evaluation using methods assessing mandibular movement range (23) were the most frequent. TMD TOMs are diverse; the major outcomes were pain, MMO, jaw function and jaw movement. Most pain outcomes are evaluated by VAS Score changes."},"publication_date":"2022-08-19","publication_name":{"en":"BMJ Open","ja":"BMJ Open"},"volume":"Vol.12","number":"No.8","starting_page":"e061387","ending_page":"e061387","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1136/bmjopen-2022-061387"],"issn":["2044-6055"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:16, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018845"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/118649","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/35868501","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=386482","label":"url"}],"paper_title":{"en":"Dual orexin receptor antagonist drug suvorexant can help in amelioration of predictable chronic mild stress-induced hyperalgesia","ja":"Dual orexin receptor antagonist drug suvorexant can help in amelioration of predictable chronic mild stress-induced hyperalgesia"},"authors":{"en":[{"name":"Chavan P"},{"name":"Chikahisa Sachiko"},{"name":"Shiuchi Tetsuya"},{"name":"Shimizu Noriyuki"},{"name":"Dalanon Junhel"},{"name":"Okura Kazuo"},{"name":"Sei Hiroyoshi"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"CHAVAN PARIMAL RAVINDRA"},{"name":"近久 幸子"},{"name":"志内 哲也"},{"name":"清水 紀之"},{"name":"Dalanon Junhel Casinillo"},{"name":"大倉 一夫"},{"name":"勢井 宏義"},{"name":"松香 芳三"}]},"description":{"en":"This study aimed to evaluate the involvement of the orexin system in predictable chronic mild stress (PCMS) and the effects of suvorexant, a dual orexin receptor antagonist, on nociceptive behavior in PCMS. Male C57BL/6 J mice were separated into various PCMS groups: a control group with sawdust on the floor of the rearing cage (C), a group with mesh wire on the floor (M), and a group with water just below the mesh wire (W). Activation of lateral hypothalamic orexin neurons was assessed using immunofluorescence. In another experiment, half of the mice in each group were administered an intraperitoneal injection of suvorexant (10 mg/kg), and the remaining mice were injected with the same amount of vehicle (normal saline). Thermal hyperalgesia was examined using tail immersion and hot plate tests, while mechanical hyperalgesia was investigated using the tail pinch test after 21 days of PCMS. Animals subjected to PCMS showed an increased percentage of activated orexin neurons in the lateral hypothalamic region after 21 days. Mice raised in the PCMS environment showed increased pain sensitivity in several pain tests; however, the symptoms were significantly reduced by suvorexant administration. The findings revealed that PCMS activates hypothalamic orexin neuronal activity, and the use of suvorexant can help attenuate PCMS-induced thermal and mechanical hyperalgesia.","ja":"This study aimed to evaluate the involvement of the orexin system in predictable chronic mild stress (PCMS) and the effects of suvorexant, a dual orexin receptor antagonist, on nociceptive behavior in PCMS. Male C57BL/6 J mice were separated into various PCMS groups: a control group with sawdust on the floor of the rearing cage (C), a group with mesh wire on the floor (M), and a group with water just below the mesh wire (W). Activation of lateral hypothalamic orexin neurons was assessed using immunofluorescence. In another experiment, half of the mice in each group were administered an intraperitoneal injection of suvorexant (10 mg/kg), and the remaining mice were injected with the same amount of vehicle (normal saline). Thermal hyperalgesia was examined using tail immersion and hot plate tests, while mechanical hyperalgesia was investigated using the tail pinch test after 21 days of PCMS. Animals subjected to PCMS showed an increased percentage of activated orexin neurons in the lateral hypothalamic region after 21 days. Mice raised in the PCMS environment showed increased pain sensitivity in several pain tests; however, the symptoms were significantly reduced by suvorexant administration. The findings revealed that PCMS activates hypothalamic orexin neuronal activity, and the use of suvorexant can help attenuate PCMS-induced thermal and mechanical hyperalgesia."},"publication_date":"2022-07-19","publication_name":{"en":"Brain Research Bulletin","ja":"Brain Research Bulletin"},"volume":"Vol.188","starting_page":"39","ending_page":"46","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.brainresbull.2022.07.011"],"issn":["1873-2747"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:17, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018848"},"force":{"see_also":[{"@id":"https://doi.org/10.3390/ijms23115878","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/118650","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=385556","label":"url"}],"paper_title":{"en":"Analgesic effect of tranilast in an animal model of neuropathic pain and its role in the regulation of tetrahydrobiopterin synthesis","ja":"Analgesic effect of tranilast in an animal model of neuropathic pain and its role in the regulation of tetrahydrobiopterin synthesis"},"authors":{"en":[{"name":"Raman S"},{"name":"Waskitho Arief"},{"name":"Raju R"},{"name":"Iwasa Takuma"},{"name":"Ikutame Daisuke"},{"name":"Okura Kazuo"},{"name":"Ohshima Masamitsu"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"RAMAN SWARNA LAKSHMI"},{"name":"Arief Waskitho"},{"name":"RESMI RAJU"},{"name":"岩浅 匠真"},{"name":"生田目 大介"},{"name":"大倉 一夫"},{"name":"大島 正充"},{"name":"松香 芳三"}]},"publication_date":"2022-05-24","publication_name":{"en":"International Journal of Molecular Sciences","ja":"International Journal of Molecular Sciences"},"volume":"Vol.23","number":"No.11","starting_page":"5878","ending_page":"5878","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/ijms23115878"],"issn":["1422-0067"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:18, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018849"},"force":{"see_also":[{"@id":"http://repo.lib.tokushima-u.ac.jp/116969","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116969","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1050010457744883840/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85128776383&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=385284","label":"url"}],"paper_title":{"en":"Orofacial pain: molecular mechanisms, diagnosis, and treatment 2021","ja":"Orofacial pain: molecular mechanisms, diagnosis, and treatment 2021"},"authors":{"en":[{"name":"Matsuka Yoshizo"}],"ja":[{"name":"松香 芳三"}]},"description":{"en":"The Special Issue ``Orofacial Pain: Molecular Mechanisms, Diagnosis, and Treatment 2021'' contains 6 articles published by 41 authors from different countries focusing on nucleus accumbens core GABAergic neurons, receptor-interacting serine/threonine-protein kinase 1, pannexin 1-mediated ATP signaling, ultra-low-frequency transcutaneous electrical nerve stimulation, and triamcinolone acetonide. The content covers several pain models, including neuropathic pain caused by peripheral nerve constriction or malpositioned dental implants, tongue cancer, myogenous temporomandibular dysfunction, and oral ulcerative mucositis. In addition, a review paper on trigeminal neuralgia is included.","ja":"The Special Issue ``Orofacial Pain: Molecular Mechanisms, Diagnosis, and Treatment 2021'' contains 6 articles published by 41 authors from different countries focusing on nucleus accumbens core GABAergic neurons, receptor-interacting serine/threonine-protein kinase 1, pannexin 1-mediated ATP signaling, ultra-low-frequency transcutaneous electrical nerve stimulation, and triamcinolone acetonide. The content covers several pain models, including neuropathic pain caused by peripheral nerve constriction or malpositioned dental implants, tongue cancer, myogenous temporomandibular dysfunction, and oral ulcerative mucositis. In addition, a review paper on trigeminal neuralgia is included."},"publication_date":"2022-04-27","publication_name":{"en":"International Journal of Molecular Sciences","ja":"International Journal of Molecular Sciences"},"volume":"Vol.23","number":"No.9","starting_page":"4826","ending_page":"4826","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/ijms23094826"],"issn":["1422-0067"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:19, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018850"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/117219","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/35431971","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85128452809&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=386834","label":"url"}],"paper_title":{"en":"Conditioned Medium From the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Neuropathic Pain in a Partial Sciatic Nerve Ligation Model.","ja":"Conditioned Medium From the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Neuropathic Pain in a Partial Sciatic Nerve Ligation Model."},"authors":{"en":[{"name":"LIU YAO"},{"name":"Kano Fumiya"},{"name":"Hashimoto Noboru"},{"name":"XIA LINZE"},{"name":"Zhou Qiao"},{"name":"Feng Xingmei"},{"name":"Hibi Hideharu"},{"name":"Miyazaki Aya"},{"name":"Iwamoto Tsutomu"},{"name":"Matsuka Yoshizo"},{"name":"Zhang Zhijun"},{"name":"Tanaka Eiji"},{"name":"Yamamoto Akihito"}],"ja":[{"name":"LIU YAO"},{"name":"加納 史也"},{"name":"橋本 登"},{"name":"夏 霖泽"},{"name":"Zhou Qiao"},{"name":"Feng Xingmei"},{"name":"Hibi Hideharu"},{"name":"宮嵜 彩"},{"name":"岩本 勉"},{"name":"松香 芳三"},{"name":"Zhang Zhijun"},{"name":"田中 栄二"},{"name":"山本 朗仁"}]},"description":{"en":"In neuropathic pain (NP), injury or diseases of the somatosensory system often result in highly debilitating chronic pain. Currently, there is no effective drug for the complete and definitive treatment of NP. We investigated the therapeutic potential of conditioned medium (CM) derived from stem cells from human exfoliated deciduous teeth (SHED-CM) against NP using a mouse partial sciatic nerve ligation (PSL) model. Abnormal pain sensation, such as tactile allodynia and hyperalgesia, can be caused by PSL. In the behavioral test, intravenous administration of SHED-CM greatly improved the PSL-induced hypersensitivity. We found that treatment with SHED-CM resulted in the recruitment of M2 macrophages in the injured sciatic nerve and ipsilateral L4/L5 dorsal root ganglion and suppressed microglial activation in the spinal cord. Notably, specific depletion of the anti-inflammatory M2 macrophages by mannosylated-Clodrosome markedly reduced the antinociceptive effect of SHED-CM. Intravenous administration of CM from M2 induced by SHED-CM (M2-CM) ameliorated the PSL-induced hypersensitivity. We found that M2-CM directly suppressed the expression of nociceptive receptors as well as proinflammatory mediators in Schwann cells. Taken together, our data suggest that SHED-CM ameliorates NP through the induction of the analgesic anti-inflammatory M2 macrophages. Thus, SHED-CM may be a novel therapeutic candidate for NP.","ja":"In neuropathic pain (NP), injury or diseases of the somatosensory system often result in highly debilitating chronic pain. Currently, there is no effective drug for the complete and definitive treatment of NP. We investigated the therapeutic potential of conditioned medium (CM) derived from stem cells from human exfoliated deciduous teeth (SHED-CM) against NP using a mouse partial sciatic nerve ligation (PSL) model. Abnormal pain sensation, such as tactile allodynia and hyperalgesia, can be caused by PSL. In the behavioral test, intravenous administration of SHED-CM greatly improved the PSL-induced hypersensitivity. We found that treatment with SHED-CM resulted in the recruitment of M2 macrophages in the injured sciatic nerve and ipsilateral L4/L5 dorsal root ganglion and suppressed microglial activation in the spinal cord. Notably, specific depletion of the anti-inflammatory M2 macrophages by mannosylated-Clodrosome markedly reduced the antinociceptive effect of SHED-CM. Intravenous administration of CM from M2 induced by SHED-CM (M2-CM) ameliorated the PSL-induced hypersensitivity. We found that M2-CM directly suppressed the expression of nociceptive receptors as well as proinflammatory mediators in Schwann cells. Taken together, our data suggest that SHED-CM ameliorates NP through the induction of the analgesic anti-inflammatory M2 macrophages. Thus, SHED-CM may be a novel therapeutic candidate for NP."},"publication_date":"2022-03","publication_name":{"en":"Frontiers in Pharmacology","ja":"Frontiers in Pharmacology"},"volume":"Vol.13","starting_page":"745020","ending_page":"745020","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3389/fphar.2022.745020"],"issn":["1663-9812"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:20, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018851"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=362959","label":"url"}],"paper_title":{"en":"Burnout is associated with amount of work and sleep quality of public-school dentists in the Caraga region","ja":"Burnout is associated with amount of work and sleep quality of public-school dentists in the Caraga region"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"松香 芳三"}]},"publication_date":"2022-03-03","publication_name":{"en":"Acta Medica Philippina","ja":"Acta Medica Philippina"},"volume":"Vol.56","number":"No.3","starting_page":"49","ending_page":"55","languages":["eng"],"referee":true,"identifiers":{"doi":["10.47895/amp.vi0.3109"],"issn":["2094-9278"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:21, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018852"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=362958","label":"url"}],"paper_title":{"en":"Spatio-temporal differences in the Filipinos search trends for toothache and milk tea","ja":"Spatio-temporal differences in the Filipinos search trends for toothache and milk tea"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Diano LM"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"Diano LM"},{"name":"松香 芳三"}]},"publication_date":"2022-03-03","publication_name":{"en":"Acta Medica Philippina","ja":"Acta Medica Philippina"},"volume":"Vol.56","number":"No.3","starting_page":"18","ending_page":"24","languages":["eng"],"referee":true,"identifiers":{"doi":["10.47895/amp.vi0.3091"],"issn":["2094-9278"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:22, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018847"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=384202","label":"url"}],"paper_title":{"en":"Botulinum toxin injection attenuates nonodontogenic toothache: A case report","ja":"Botulinum toxin injection attenuates nonodontogenic toothache: A case report"},"authors":{"en":[{"name":"Chavan P"},{"name":"Raman S"},{"name":"Waskitho Arief"},{"name":"Dalanon Junhel"},{"name":"Yoshihara Yasutomo"},{"name":"Okura Kazuo"},{"name":"Miyamoto Ryosuke"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"CHAVAN PARIMAL RAVINDRA"},{"name":"RAMAN SWARNA LAKSHMI"},{"name":"Arief Waskitho"},{"name":"Dalanon Junhel Casinillo"},{"name":"吉原 靖智"},{"name":"大倉 一夫"},{"name":"宮本 亮介"},{"name":"松香 芳三"}]},"publication_date":"2022-02","publication_name":{"en":"Clinical Case Reports","ja":"Clinical Case Reports"},"volume":"Vol.10","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1002/ccr3.5494"],"issn":["2050-0904"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:23, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116383","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=382624","label":"url"}],"paper_title":{"en":"Peripherally Administered Botulinum Toxin Type A Localizes Bilaterally in Trigeminal Ganglia of Animal Model","ja":"Peripherally Administered Botulinum Toxin Type A Localizes Bilaterally in Trigeminal Ganglia of Animal Model"},"authors":{"en":[{"name":"Waskitho Arief"},{"name":"Yamamoto Yumiko"},{"name":"Raman S"},{"name":"Kano Fumiya"},{"name":"Yan Huijiao"},{"name":"Raju R"},{"name":"Afroz S"},{"name":"Morita Tsuyoshi"},{"name":"Ikutame Daisuke"},{"name":"Okura Kazuo"},{"name":"Ohshima Masamitsu"},{"name":"Yamamoto Akihito"},{"name":"Baba Otto"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"ARIEF WASKITHO"},{"name":"Yamamoto Yumiko"},{"name":"RAMAN SWARNA LAKSHMI"},{"name":"加納 史也"},{"name":"YAN HUIJIAO"},{"name":"RESMI RAJU"},{"name":"SHAISTA AFROZ"},{"name":"守田 剛"},{"name":"生田目 大介"},{"name":"大倉 一夫"},{"name":"大島 正充"},{"name":"山本 朗仁"},{"name":"馬場 麻人"},{"name":"松香 芳三"}]},"publication_date":"2021-10-05","publication_name":{"en":"Toxins","ja":"Toxins"},"volume":"Vol.13","number":"No.10","starting_page":"704","ending_page":"704","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/toxins13100704"],"issn":["2072-6651"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:24, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/117029","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/34583551","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=382205","label":"url"}],"paper_title":{"en":"Dentin-pulp complex tissue regeneration via three-dimensional cell sheet layering","ja":"Dentin-pulp complex tissue regeneration via three-dimensional cell sheet layering"},"authors":{"en":[{"name":"Yan Huijiao"},{"name":"Ohshima Masamitsu"},{"name":"Raju Raju"},{"name":"Raman S"},{"name":"Sekine Kazumitsu"},{"name":"Waskitho Arief"},{"name":"Inoue Miho"},{"name":"Inoue Masahisa"},{"name":"Baba Otto"},{"name":"Morita Tsuyoshi"},{"name":"Miyagi Mayu"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"YAN HUIJIAO"},{"name":"大島 正充"},{"name":"RESMI RAJU"},{"name":"RAMAN SWARNA LAKSHMI"},{"name":"関根 一光"},{"name":"ARIEF WASKITHO"},{"name":"井上 美穂"},{"name":"Inoue Masahisa"},{"name":"馬場 麻人"},{"name":"守田 剛"},{"name":"宮城 麻友"},{"name":"松香 芳三"}]},"description":{"en":"The dentin-pulp complex is a unique structure in teeth that contains both hard and soft tissues. Generally, deep caries and trauma cause damage to the dentin-pulp complex, and if left untreated, this damage will progress to irreversible pulpitis. The aim of this study was to fabricate a layered cell sheet composed of rat dental pulp (DP) cells and odontogenic differentiation of pulp (OD) cells and to investigate the ability to regenerate the dentin-pulp complex in a scaffold tooth. We fabricated two single cell sheets composed of DP cells (DP cell sheet) or OD cells (OD cell sheet) and a layered cell sheet made by layering both cells. The characteristics of the fabricated cell sheets were analyzed using light microscopy, scanning electron microscope (SEM), hematoxylin-eosin (HE) staining, and immunohistochemistry (IHC). Furthermore, the cell sheets were transplanted into the subrenal capsule of immunocompromised mice for 8 weeks. After this, the regenerative capacity to form dentin-like tissue was evaluated using micro-computed tomography (micro-CT), HE staining, and IHC. The findings of SEM and IHC confirmed that layered cell sheets fabricated by stacking OD cells and DP cells maintained their cytological characteristics. Micro-CT of layered cell sheet transplants revealed a mineralized capping of the access cavity in the crown area, similar to that of natural dentin. In contrast, the OD cell sheet group demonstrated the formation of irregular fragments of mineralized tissue in the pulp cavity, and the DP cell sheet did not develop any hard tissue. Moreover, bone volume/tissue volume (BV/TV) showed a significant increase in hard tissue formation in the layered cell sheet group compared with that in the single cell sheet group ( < 0.05). HE staining also showed a combination of soft and hard tissue formation in the layered cell sheet group. Furthermore, IHC confirmed that the dentin-like tissue generated from the layered cell sheet expressed characteristic markers of dentin but not bone equivalent to that of a natural tooth. In conclusion, this study demonstrates the feasibility of regenerating dentin-pulp complex using a bioengineered tissue designed to simulate the anatomical structure. Impact statement The dentin-pulp complex can be destroyed by deep caries and trauma, which may cause pulpitis and progress to irreversible pulpitis, apical periodontitis, and even tooth loss. Current treatments cannot maintain pulp health, and teeth can become brittle. We developed a three-dimensional (3D) layered cell sheet using dental pulp cells and odontogenic differentiation of pulp cells for dentin-pulp complex regeneration. Our layered cell sheet enables the regeneration of an organized 3D dentin-pulp-like structure comparable with that of natural teeth. This layered cell sheet technology may contribute to dentin-pulp complex regeneration and provide a novel method for complex tissue engineering.","ja":"The dentin-pulp complex is a unique structure in teeth that contains both hard and soft tissues. Generally, deep caries and trauma cause damage to the dentin-pulp complex, and if left untreated, this damage will progress to irreversible pulpitis. The aim of this study was to fabricate a layered cell sheet composed of rat dental pulp (DP) cells and odontogenic differentiation of pulp (OD) cells and to investigate the ability to regenerate the dentin-pulp complex in a scaffold tooth. We fabricated two single cell sheets composed of DP cells (DP cell sheet) or OD cells (OD cell sheet) and a layered cell sheet made by layering both cells. The characteristics of the fabricated cell sheets were analyzed using light microscopy, scanning electron microscope (SEM), hematoxylin-eosin (HE) staining, and immunohistochemistry (IHC). Furthermore, the cell sheets were transplanted into the subrenal capsule of immunocompromised mice for 8 weeks. After this, the regenerative capacity to form dentin-like tissue was evaluated using micro-computed tomography (micro-CT), HE staining, and IHC. The findings of SEM and IHC confirmed that layered cell sheets fabricated by stacking OD cells and DP cells maintained their cytological characteristics. Micro-CT of layered cell sheet transplants revealed a mineralized capping of the access cavity in the crown area, similar to that of natural dentin. In contrast, the OD cell sheet group demonstrated the formation of irregular fragments of mineralized tissue in the pulp cavity, and the DP cell sheet did not develop any hard tissue. Moreover, bone volume/tissue volume (BV/TV) showed a significant increase in hard tissue formation in the layered cell sheet group compared with that in the single cell sheet group ( < 0.05). HE staining also showed a combination of soft and hard tissue formation in the layered cell sheet group. Furthermore, IHC confirmed that the dentin-like tissue generated from the layered cell sheet expressed characteristic markers of dentin but not bone equivalent to that of a natural tooth. In conclusion, this study demonstrates the feasibility of regenerating dentin-pulp complex using a bioengineered tissue designed to simulate the anatomical structure. Impact statement The dentin-pulp complex can be destroyed by deep caries and trauma, which may cause pulpitis and progress to irreversible pulpitis, apical periodontitis, and even tooth loss. Current treatments cannot maintain pulp health, and teeth can become brittle. We developed a three-dimensional (3D) layered cell sheet using dental pulp cells and odontogenic differentiation of pulp cells for dentin-pulp complex regeneration. Our layered cell sheet enables the regeneration of an organized 3D dentin-pulp-like structure comparable with that of natural teeth. This layered cell sheet technology may contribute to dentin-pulp complex regeneration and provide a novel method for complex tissue engineering."},"publication_date":"2021-10","publication_name":{"en":"Tissue Engineering. Part C, Methods","ja":"Tissue Engineering. Part C, Methods"},"volume":"Vol.27","number":"No.10","starting_page":"559","ending_page":"570","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1089/ten.TEC.2021.0171"],"issn":["1937-3392"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:25, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018854"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116287","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390570784697431168/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=381779","label":"url"}],"paper_title":{"en":"Low-intensity pulsed ultrasound ameliorates neuropathic pain induced by partial sciatic nerve ligation via regulating macrophage polarization","ja":"Low-intensity pulsed ultrasound ameliorates neuropathic pain induced by partial sciatic nerve ligation via regulating macrophage polarization"},"authors":{"en":[{"name":"Liu Yao"},{"name":"Xia Linze"},{"name":"Kano Fumiya"},{"name":"Hashimoto Noboru"},{"name":"Matsuka Yoshizo"},{"name":"Yamamoto Akihito"},{"name":"Tanaka Eiji"}],"ja":[{"name":"Liu Yao"},{"name":"夏 霖?"},{"name":"加納 史也"},{"name":"橋本 登"},{"name":"松香 芳三"},{"name":"山本 朗仁"},{"name":"田中 栄二"}]},"publication_date":"2021-09-08","publication_name":{"en":"Journal of Oral Health and Biosciences","ja":"Journal of Oral Health and Biosciences"},"volume":"Vol.34","starting_page":"11","ending_page":"18","languages":["eng"],"referee":true,"identifiers":{"doi":["10.20738/johb.34.1_11"],"issn":["2189-6682"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:26, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018855"},"force":{"see_also":[{"@id":"http://repo.lib.tokushima-u.ac.jp/116284","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116284","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390852259674142080/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=373671","label":"url"}],"paper_title":{"en":"Longitudinal comparison between flipped classroom and team-based learning in a prosthodontic class","ja":"Longitudinal comparison between flipped classroom and team-based learning in a prosthodontic class"},"authors":{"en":[{"name":"Hayama Rika"},{"name":"Okura Kazuo"},{"name":"Ohshima Masamitsu"},{"name":"Hosoki Maki"},{"name":"Suzuki Yoshitaka"},{"name":"Miyagi Mayu"},{"name":"Inoue Miho"},{"name":"Iwasa Takuma"},{"name":"Dalanon Junhel"},{"name":"Resmi Raju"},{"name":"Rodis Omar"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"葉山 莉香"},{"name":"大倉 一夫"},{"name":"大島 正充"},{"name":"細木 眞紀"},{"name":"鈴木 善貴"},{"name":"宮城 麻友"},{"name":"井上 美穂"},{"name":"岩浅 匠真"},{"name":"Dalanon Junhel Casinillo"},{"name":"RESMI RAJU"},{"name":"ロディス オマー"},{"name":"松香 芳三"}]},"description":{"en":"Active learning is a concept that allows students to study and learn actively by themselves to get knowledge. There are several methods of active learning, including flipped classroom (FC) and team-based learning (TBL). In FC, students are required to study before classes. In TBL, students also study before class, take individual readiness assurance test (iRAT) and team readiness assurance test (tRAT), then discuss group assignment projects (GAPs) during class. The purpose of this study was to compare the effectiveness between FC and TBL.
The effectiveness of FC and TBL was assessed from the results of the term-end examinations, questionnaires and practice examinations. To check the difficulty of the term-end examinations, control dentists took the same examinations and we calculated the equating score with item response theory.
Statistical analysis showed that the correct answer rate in term-end examinations was significantly different in comparison with the time of the trial, and for the participants (students and dentists). The term-end examination score of FC and TBL did not show a statistical difference. The student questionnaire showed that TBL had higher scores than FC on various factors such as student positive attitude, preparation, ingenuity of teacher and achieving the class goals. The crown & bridge score from the practice examination of 6th-year students who had FC + TBL were constantly higher than the Japanese national average score. The identification index of FC and TBL did not show the statistical difference and there was no statistical difference on item response theory between FC and TBL.","ja":"Active learning is a concept that allows students to study and learn actively by themselves to get knowledge. There are several methods of active learning, including flipped classroom (FC) and team-based learning (TBL). In FC, students are required to study before classes. In TBL, students also study before class, take individual readiness assurance test (iRAT) and team readiness assurance test (tRAT), then discuss group assignment projects (GAPs) during class. The purpose of this study was to compare the effectiveness between FC and TBL.
The effectiveness of FC and TBL was assessed from the results of the term-end examinations, questionnaires and practice examinations. To check the difficulty of the term-end examinations, control dentists took the same examinations and we calculated the equating score with item response theory.
Statistical analysis showed that the correct answer rate in term-end examinations was significantly different in comparison with the time of the trial, and for the participants (students and dentists). The term-end examination score of FC and TBL did not show a statistical difference. The student questionnaire showed that TBL had higher scores than FC on various factors such as student positive attitude, preparation, ingenuity of teacher and achieving the class goals. The crown & bridge score from the practice examination of 6th-year students who had FC + TBL were constantly higher than the Japanese national average score. The identification index of FC and TBL did not show the statistical difference and there was no statistical difference on item response theory between FC and TBL."},"publication_date":"2021-09-08","publication_name":{"en":"Journal of Oral Health and Biosciences","ja":"Journal of Oral Health and Biosciences"},"volume":"Vol.34","number":"No.1","starting_page":"1","ending_page":"10","languages":["eng"],"referee":true,"identifiers":{"doi":["10.20738/johb.34.1_1"],"issn":["2189-6682"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:27, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018856"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116682","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/34319034","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85111726763&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=382961","label":"url"}],"paper_title":{"en":"Decreased global interest in oral cancer during the COVID-19 pandemic","ja":"Decreased global interest in oral cancer during the COVID-19 pandemic"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"松香 芳三"}]},"description":{"en":"Oral cancer is one of the most common malignancies in developing countries, but studies using global data are scarce. The aim of this study is to analyze the search interests for oral cancer using mouth cancer, tongue cancer, gum cancer, and lip cancer as common keywords. Internet searches relating to oral cancer from 2010 to 2020, from 250 countries and dependent areas, were retrieved from Google Trends. Color densities in a heat map were used to show geographic differences. Kruskal-Wallis test with post hoc Dunn's analysis was used to perform yearly comparisons of searches for mouth cancer, tongue cancer, gum cancer, and lip cancer. Search results within 2020 were also compared to determine differences. Forecasting searches from 2021 to 2022 were done by fitting time series models. From 29 of 250 (11.6%) countries, the highest search values were observed for mouth cancer in Sri Lanka, Qatar, Bangladesh, Finland, Netherlands, Spain, and France. Compared to 2020, greater searches were seen in 2018 (Mdn = 91%, P = 0.023) and 2019 (Mdn = 94%, P = 0.012) for mouth cancer, and 2019 (Mdn = 17%, P = 0.035) for lip cancer. The relative search volumes for gum cancer and lip cancer were substantially lower than mouth cancer during the COVID-19 pandemic. Higher-income countries tend to be more interested in seeking information about oral cancer. Noteworthy decline in the interest in seeking information online for oral cancer may have crucial implications during the COVID-19 pandemic. Google Trends offer an invaluable and inexpensive means for oral cancer surveillance and health-seeking behavior.
.","ja":"Oral cancer is one of the most common malignancies in developing countries, but studies using global data are scarce. The aim of this study is to analyze the search interests for oral cancer using mouth cancer, tongue cancer, gum cancer, and lip cancer as common keywords. Internet searches relating to oral cancer from 2010 to 2020, from 250 countries and dependent areas, were retrieved from Google Trends. Color densities in a heat map were used to show geographic differences. Kruskal-Wallis test with post hoc Dunn's analysis was used to perform yearly comparisons of searches for mouth cancer, tongue cancer, gum cancer, and lip cancer. Search results within 2020 were also compared to determine differences. Forecasting searches from 2021 to 2022 were done by fitting time series models. From 29 of 250 (11.6%) countries, the highest search values were observed for mouth cancer in Sri Lanka, Qatar, Bangladesh, Finland, Netherlands, Spain, and France. Compared to 2020, greater searches were seen in 2018 (Mdn = 91%, P = 0.023) and 2019 (Mdn = 94%, P = 0.012) for mouth cancer, and 2019 (Mdn = 17%, P = 0.035) for lip cancer. The relative search volumes for gum cancer and lip cancer were substantially lower than mouth cancer during the COVID-19 pandemic. Higher-income countries tend to be more interested in seeking information about oral cancer. Noteworthy decline in the interest in seeking information online for oral cancer may have crucial implications during the COVID-19 pandemic. Google Trends offer an invaluable and inexpensive means for oral cancer surveillance and health-seeking behavior.
."},"publication_date":"2021-07-01","publication_name":{"en":"Asian Pacific Journal of Cancer Prevention : APJCP","ja":"Asian Pacific Journal of Cancer Prevention : APJCP"},"volume":"Vol.22","number":"No.7","starting_page":"2117","ending_page":"2124","languages":["eng"],"referee":true,"identifiers":{"doi":["10.31557/APJCP.2021.22.7.2117"],"issn":["2476-762X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:28, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116124","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85109198478&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=376652","label":"url"}],"paper_title":{"en":"Risk factors for tooth loss in patients with 25 remaining teeth undergoing mid-long-term","ja":"Risk factors for tooth loss in patients with 25 remaining teeth undergoing mid-long-term"},"authors":{"en":[{"name":"Kawahara Hiroo"},{"name":"Inoue Miho"},{"name":"Okura Kazuo"},{"name":"Ohshima Masamitsu"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Kawahara Hiroo"},{"name":"井上 美穂"},{"name":"大倉 一夫"},{"name":"大島 正充"},{"name":"松香 芳三"}]},"publication_date":"2021-07","publication_name":{"en":"International Journal of Environmental Research and Public Health","ja":"International Journal of Environmental Research and Public Health"},"volume":"Vol.18","number":"No.13","starting_page":"7174","ending_page":"7174","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/ijerph18137174"],"issn":["1660-4601"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:29, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116125","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85109362985&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=376593","label":"url"}],"paper_title":{"en":"Pain sensitivity increases with sleep disturbance under predictable chronic mild stress in mice","ja":"Pain sensitivity increases with sleep disturbance under predictable chronic mild stress in mice"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Chikahisa Sachiko"},{"name":"Shiuchi Tetsuya"},{"name":"Shimizu Noriyuki"},{"name":"Chavan P"},{"name":"Suzuki Yoshitaka"},{"name":"Okura Kazuo"},{"name":"Sei Hiroyoshi"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"近久 幸子"},{"name":"志内 哲也"},{"name":"清水 紀之"},{"name":"CHAVAN PARIMAL RAVINDRA"},{"name":"鈴木 善貴"},{"name":"大倉 一夫"},{"name":"勢井 宏義"},{"name":"松香 芳三"}]},"publication_date":"2021-07","publication_name":{"en":"Scientific Reports","ja":"Scientific Reports"},"volume":"Vol.11","number":"No.1","starting_page":"14231","ending_page":"14231","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1038/s41598-021-93560-7"],"issn":["2045-2322"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:30, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/33492675","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=373282","label":"url"}],"paper_title":{"en":"Effects of sitting posture and jaw clenching on neck and trunk muscle activities during typing","ja":"Effects of sitting posture and jaw clenching on neck and trunk muscle activities during typing"},"authors":{"en":[{"name":"Tomita Yousuke"},{"name":"Suzuki Yoshitaka"},{"name":"Tanaka Yuto"},{"name":"Hasegawa Yoko"},{"name":"Yoshihara Yasutomo"},{"name":"Okura Kazuo"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Tomita Yousuke"},{"name":"鈴木 善貴"},{"name":"Tanaka Yuto"},{"name":"Hasegawa Yoko"},{"name":"吉原 靖智"},{"name":"大倉 一夫"},{"name":"松香 芳三"}]},"description":{"en":"Neck pain is one of the most common musculoskeletal complaints. Evidence suggests that increased activities of neck and trunk muscles are one of the mechanisms related to neck pain. Jaw clenching and sitting posture may modulate the muscle activity in neck and trunk muscles during typing. The present study aimed to assess the effects of different postural positions and clenching conditions on neck and trunk muscle activities. Thirteen healthy adults (39.8 ± 5.0 years) performed computer typing tasks in four conditions (two postural positions [upright vs slouched] and two jaw clenching conditions [clenching vs non-clenching]). Integrated surface electromyography (iEMG) was measured in sternocleidomastoid (SCM), upper trapezius (uTP) and middle trapezius (mTP) muscles and compared between conditions. The Friedman and Wilcoxon signed-rank tests with Bonferroni's corrections were used to estimate the condition-specific differences in the iEMG data. The statistical significance level was set at 5%. In both postural positions, iEMG was significantly greater under the jaw clenching than under the non-clenching condition (χ = 21.700, P < .01). Under both jaw clenching conditions, iEMG was significantly greater in the slouched than in the upright postural position (χ = 23.182, P < .01). No significant differences in iEMG were seen across conditions (χ = 5.018, P = .10). Sitting posture and jaw clenching appear to influence activities of different muscles.","ja":"Neck pain is one of the most common musculoskeletal complaints. Evidence suggests that increased activities of neck and trunk muscles are one of the mechanisms related to neck pain. Jaw clenching and sitting posture may modulate the muscle activity in neck and trunk muscles during typing. The present study aimed to assess the effects of different postural positions and clenching conditions on neck and trunk muscle activities. Thirteen healthy adults (39.8 ± 5.0 years) performed computer typing tasks in four conditions (two postural positions [upright vs slouched] and two jaw clenching conditions [clenching vs non-clenching]). Integrated surface electromyography (iEMG) was measured in sternocleidomastoid (SCM), upper trapezius (uTP) and middle trapezius (mTP) muscles and compared between conditions. The Friedman and Wilcoxon signed-rank tests with Bonferroni's corrections were used to estimate the condition-specific differences in the iEMG data. The statistical significance level was set at 5%. In both postural positions, iEMG was significantly greater under the jaw clenching than under the non-clenching condition (χ = 21.700, P < .01). Under both jaw clenching conditions, iEMG was significantly greater in the slouched than in the upright postural position (χ = 23.182, P < .01). No significant differences in iEMG were seen across conditions (χ = 5.018, P = .10). Sitting posture and jaw clenching appear to influence activities of different muscles."},"publication_date":"2021-05","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.48","number":"No.5","starting_page":"568","ending_page":"574","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/joor.13152"],"issn":["1365-2842"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:31, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39213770"},"force":{"see_also":[{"@id":"http://id.ndl.go.jp/bib/031313513","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520572359516377600/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=372461","label":"url"}],"paper_title":{"en":"インドネシアの歯学部における学部教育","ja":"インドネシアの歯学部における学部教育"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Ohshima Masamitsu"},{"name":"Okura Kazuo"},{"name":"Hosoki Maki"},{"name":"Suzuki Yoshitaka"},{"name":"Miyagi Mayu"},{"name":"Inoue Miho"}],"ja":[{"name":"松香 芳三"},{"name":"大島 正充"},{"name":"大倉 一夫"},{"name":"細木 眞紀"},{"name":"鈴木 善貴"},{"name":"宮城 麻友"},{"name":"井上 美穂"}]},"publication_date":"2020-12","publication_name":{"en":"The Journal of Japan Association of Oral Rehabilitation","ja":"日本口腔リハビリテーション学会雑誌"},"volume":"Vol.33","number":"No.1","starting_page":"53","ending_page":"57","languages":["jpn"],"referee":true,"identifiers":{"issn":["2186-2052"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:32, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/33081336","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=371811","label":"url"}],"paper_title":{"en":"Immediate Effect of Masticatory Muscle Activity with Transcutaneous Electrical Nerve Stimulation in Muscle Pain of Temporomandibular Disorders Patients","ja":"Immediate Effect of Masticatory Muscle Activity with Transcutaneous Electrical Nerve Stimulation in Muscle Pain of Temporomandibular Disorders Patients"},"authors":{"en":[{"name":"Abe Susumu"},{"name":"Akane Miyagi"},{"name":"Yoshinaga Kaoru"},{"name":"Matsuka Yoshizo"},{"name":"Matsumoto Fumihiro"},{"name":"Emi Uyama"},{"name":"Suzuki Yoshitaka"},{"name":"Ohshima Masamitsu"},{"name":"Okura Kazuo"},{"name":"Tanaka Eiji"}],"ja":[{"name":"安陪 晋"},{"name":"宮城 茜"},{"name":"吉永 薫"},{"name":"松香 芳三"},{"name":"松本 文博"},{"name":"宇山 恵美"},{"name":"鈴木 善貴"},{"name":"大島 正充"},{"name":"大倉 一夫"},{"name":"田中 栄二"}]},"description":{"en":"Transcutaneous electrical nerve stimulation (TENS) is a non-invasive treatment modality for acute and chronic pain. However, little information for muscle activity is available on the immediate effects of TENS in masticatory muscle pain related to temporomandibular disorders (TMDs). The present study aimed to evaluate the immediate effects of TENS treatment on TMD-related muscle pain. Thirty-six patients with TMD-related muscle pain and 39 healthy subjects served as TMD and control groups, respectively. For objective evaluations, maximum mouth opening, and maximum bite force were measured before and after TENS. The pain intensity was assessed according to a 100-mm visual analog scale (VAS). TENS was applied to painful muscles for 20 min with frequencies of 100-200 Hz. The treatment outcome was evaluated using Global Rating of Change (GRC) scales. In the TMD group, VAS values significantly decreased after TENS. Although there was significant increase in the maximum mouth opening after TENS for only TMD group, the maximum bite force of both groups was significantly greater after TENS. According to GRC scales, one patient with TMD-related muscle pain expressed negative feelings after TENS. Conclusively, TENS treatment might quickly relieve pain in masticatory muscles and improve masticatory functions in patients with TMD-related muscle pain.","ja":"Transcutaneous electrical nerve stimulation (TENS) is a non-invasive treatment modality for acute and chronic pain. However, little information for muscle activity is available on the immediate effects of TENS in masticatory muscle pain related to temporomandibular disorders (TMDs). The present study aimed to evaluate the immediate effects of TENS treatment on TMD-related muscle pain. Thirty-six patients with TMD-related muscle pain and 39 healthy subjects served as TMD and control groups, respectively. For objective evaluations, maximum mouth opening, and maximum bite force were measured before and after TENS. The pain intensity was assessed according to a 100-mm visual analog scale (VAS). TENS was applied to painful muscles for 20 min with frequencies of 100-200 Hz. The treatment outcome was evaluated using Global Rating of Change (GRC) scales. In the TMD group, VAS values significantly decreased after TENS. Although there was significant increase in the maximum mouth opening after TENS for only TMD group, the maximum bite force of both groups was significantly greater after TENS. According to GRC scales, one patient with TMD-related muscle pain expressed negative feelings after TENS. Conclusively, TENS treatment might quickly relieve pain in masticatory muscles and improve masticatory functions in patients with TMD-related muscle pain."},"publication_date":"2020-10-16","publication_name":{"en":"Journal of Clinical Medicine","ja":"Journal of Clinical Medicine"},"volume":"Vol.9","number":"No.10","starting_page":"3330","ending_page":"3330","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/jcm9103330"],"issn":["2077-0383"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:33, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/32404562","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=366223","label":"url"}],"paper_title":{"en":"Evaluation of the measurement precision and accuracy in the dental CAD/CAM system","ja":"Evaluation of the measurement precision and accuracy in the dental CAD/CAM system"},"authors":{"en":[{"name":"Okawa Toshinori"},{"name":"Abe Susumu"},{"name":"Nakano Masanori"},{"name":"Oka Kenji"},{"name":"Horikawa E"},{"name":"Matsuka Yoshizo"},{"name":"Kawano Fumiaki"}],"ja":[{"name":"大川 敏永"},{"name":"安陪 晋"},{"name":"中野 雅德"},{"name":"岡 謙次"},{"name":"Horikawa E"},{"name":"松香 芳三"},{"name":"河野 文昭"}]},"description":{"en":"The purpose of this study is to investigate the precision and trueness of the occlusal contact record obtained with a dental CAD/CAM device (ARCTICA). Sandblasted spherical steel balls with diameters of 10-20 mm were measured using ARCTICA and a three-dimensional measurement device (FN503). The radius of each steel ball was calculated from the measured value and the difference between the measured and nominal values was obtained. Upper/lower dental arch casts were measured and processed for occlusal contact image creation using both devices. The graphical images of the occlusal contacts at the intercuspal position obtained from both systems and an occlusal analysis device (BE-1) were compared with the occlusal contact area. Excellent correlation was observed between the measurement results of ARCTICA and FN503 (p<0.001, R: 0.99). The occlusal contact areas were 186.0 mm (ARCTICA), 192.8 mm (FN503), and 196.1 mm (BE-1). This study showed that ARCTICA is capable of conducting highly accurate measurements and generating a graphical image of occlusal contacts with good reliability.","ja":"The purpose of this study is to investigate the precision and trueness of the occlusal contact record obtained with a dental CAD/CAM device (ARCTICA). Sandblasted spherical steel balls with diameters of 10-20 mm were measured using ARCTICA and a three-dimensional measurement device (FN503). The radius of each steel ball was calculated from the measured value and the difference between the measured and nominal values was obtained. Upper/lower dental arch casts were measured and processed for occlusal contact image creation using both devices. The graphical images of the occlusal contacts at the intercuspal position obtained from both systems and an occlusal analysis device (BE-1) were compared with the occlusal contact area. Excellent correlation was observed between the measurement results of ARCTICA and FN503 (p<0.001, R: 0.99). The occlusal contact areas were 186.0 mm (ARCTICA), 192.8 mm (FN503), and 196.1 mm (BE-1). This study showed that ARCTICA is capable of conducting highly accurate measurements and generating a graphical image of occlusal contacts with good reliability."},"publication_date":"2020-09-29","publication_name":{"en":"Dental Materials Journal","ja":"Dental Materials Journal"},"volume":"Vol.39","number":"No.5","starting_page":"784-791","ending_page":"784-791","languages":["eng"],"referee":true,"identifiers":{"doi":["10.4012/dmj.2019-157"],"issn":["1881-1361"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:34, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018858"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=365573","label":"url"}],"paper_title":{"en":"Forecasting interest in health professions education based on relative search volume trends from the Philippines","ja":"Forecasting interest in health professions education based on relative search volume trends from the Philippines"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"松香 芳三"}]},"publication_date":"2020-09","publication_name":{"en":"Health Professions Education","ja":"Health Professions Education"},"volume":"Vol.6","number":"No.3","starting_page":"368","ending_page":"375","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.hpe.2020.04.010"],"issn":["2452-3011"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:35, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/115160","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/32867387","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=370197","label":"url"}],"paper_title":{"en":"Risk factors for tooth loss in patients undergoing mid long-term maintenance: A retrospective study","ja":"Risk factors for tooth loss in patients undergoing mid long-term maintenance: A retrospective study"},"authors":{"en":[{"name":"Kawahara H,"},{"name":"Inoue Miho"},{"name":"Okura Kazuo"},{"name":"Ohshima Masamitsu"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"川原 博雄"},{"name":"井上 美穂"},{"name":"大倉 一夫"},{"name":"大島 正充"},{"name":"松香 芳三"}]},"description":{"en":"In this retrospective study, we identified risk factors for tooth loss in patients undergoing mid-long-term maintenance therapy. We surveyed 674 maintenance patients for ≥5 years after active treatment who visited a dental clinic between January 2015 and December 2016. Of these, 265 were men (mean age 54.6 ± 8.0 years old) and 409 were women (mean age 54.0 ± 7.9 years old). Study variables included patient compliance, sex, number of teeth lost, cause of tooth loss (dental caries, periodontal disease, root fracture, others, vital or non-vital teeth), age at start of maintenance, number of remaining teeth at start of maintenance, smoking, use of salivary secretion inhibitors, presence of diabetes mellitus, condition of periodontal bone loss, and use of a removable denture. Most lost teeth were non-vital teeth (91.7% of all cases) and the most common cause of tooth loss was tooth fracture (62.1% of all cases). A statistically significant risk factors for tooth loss was number of remaining teeth at the start of maintenance ( = 0.003).","ja":"In this retrospective study, we identified risk factors for tooth loss in patients undergoing mid-long-term maintenance therapy. We surveyed 674 maintenance patients for ≥5 years after active treatment who visited a dental clinic between January 2015 and December 2016. Of these, 265 were men (mean age 54.6 ± 8.0 years old) and 409 were women (mean age 54.0 ± 7.9 years old). Study variables included patient compliance, sex, number of teeth lost, cause of tooth loss (dental caries, periodontal disease, root fracture, others, vital or non-vital teeth), age at start of maintenance, number of remaining teeth at start of maintenance, smoking, use of salivary secretion inhibitors, presence of diabetes mellitus, condition of periodontal bone loss, and use of a removable denture. Most lost teeth were non-vital teeth (91.7% of all cases) and the most common cause of tooth loss was tooth fracture (62.1% of all cases). A statistically significant risk factors for tooth loss was number of remaining teeth at the start of maintenance ( = 0.003)."},"publication_date":"2020-08-27","publication_name":{"en":"International Journal of Environmental Research and Public Health","ja":"International Journal of Environmental Research and Public Health"},"volume":"Vol.17","number":"No.17","starting_page":"E6258","ending_page":"E6258","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/ijerph17176258"],"issn":["1660-4601"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:36, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/115116","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/32825453","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85089699772&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=368866","label":"url"}],"paper_title":{"en":"Role of CGRP in neuroimmune interaction via NFkB signalling genes in glial cells of trigeminal ganglia","ja":"Role of CGRP in neuroimmune interaction via NFkB signalling genes in glial cells of trigeminal ganglia"},"authors":{"en":[{"name":"Afroz S"},{"name":"Arakaki Rieko"},{"name":"Iwasa Takuma"},{"name":"Waskitho Arief"},{"name":"Ohshima Masamitsu"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"SHAISTA AFROZ"},{"name":"新垣 理恵子"},{"name":"岩浅 匠真"},{"name":"ARIEF WASKITHO"},{"name":"大島 正充"},{"name":"松香 芳三"}]},"description":{"en":"Activation of the trigeminal system causes the release of various neuropeptides, cytokines, and other immune mediators. Calcitonin gene-related peptide (CGRP), which is a potent algogenic mediator, is expressed in the peripheral sensory neurons of trigeminal ganglion (TG). It affects the inflammatory responses and pain sensitivity by modulating the activity of glial cells. The primary aim of this study was to use array analysis to investigate the effect of CGRP on the glial cells of TG in regulating nuclear factor kappa B (NF-κB) signaling genes and to further check if CGRP in the TG can affect neuron-glia activation in the spinal trigeminal nucleus caudalis. The glial cells of TG were stimulated with CGRP or Minocycline (Min) + CGRP. The effect on various genes involved in NF-κB signaling pathway was analyzed compared to no treatment control condition using a PCR array analysis. CGRP, Min + CGRP or saline was directly injected inside the TG and the effect on gene expression of , and and protein expression of cleaved Caspase3 (cleav Casp3) in the TG, and c-Fos and glial fibrillary acidic protein (GFAP) in the spinal section containing trigeminal nucleus caudalis was analyzed. Results showed that CGRP stimulation resulted in the modulation of several genes involved in the interleukin 1 signaling pathway and some genes of the tumor necrosis factor pathway. Minocycline pre-treatment resulted in the modulation of several genes in the glial cells, including anti-inflammatory genes, and neuronal activation markers. A mild increase in cleav Casp3 expression in TG and c-Fos and GFAP in the spinal trigeminal nucleus of CGRP injected animals was observed. These data provide evidence that glial cells can participate in neuroimmune interaction due to CGRP in the TG via NF-κB signaling pathway.","ja":"Activation of the trigeminal system causes the release of various neuropeptides, cytokines, and other immune mediators. Calcitonin gene-related peptide (CGRP), which is a potent algogenic mediator, is expressed in the peripheral sensory neurons of trigeminal ganglion (TG). It affects the inflammatory responses and pain sensitivity by modulating the activity of glial cells. The primary aim of this study was to use array analysis to investigate the effect of CGRP on the glial cells of TG in regulating nuclear factor kappa B (NF-κB) signaling genes and to further check if CGRP in the TG can affect neuron-glia activation in the spinal trigeminal nucleus caudalis. The glial cells of TG were stimulated with CGRP or Minocycline (Min) + CGRP. The effect on various genes involved in NF-κB signaling pathway was analyzed compared to no treatment control condition using a PCR array analysis. CGRP, Min + CGRP or saline was directly injected inside the TG and the effect on gene expression of , and and protein expression of cleaved Caspase3 (cleav Casp3) in the TG, and c-Fos and glial fibrillary acidic protein (GFAP) in the spinal section containing trigeminal nucleus caudalis was analyzed. Results showed that CGRP stimulation resulted in the modulation of several genes involved in the interleukin 1 signaling pathway and some genes of the tumor necrosis factor pathway. Minocycline pre-treatment resulted in the modulation of several genes in the glial cells, including anti-inflammatory genes, and neuronal activation markers. A mild increase in cleav Casp3 expression in TG and c-Fos and GFAP in the spinal trigeminal nucleus of CGRP injected animals was observed. These data provide evidence that glial cells can participate in neuroimmune interaction due to CGRP in the TG via NF-κB signaling pathway."},"publication_date":"2020-08-20","publication_name":{"en":"International Journal of Molecular Sciences","ja":"International Journal of Molecular Sciences"},"volume":"Vol.21","number":"No.17","starting_page":"6005","ending_page":"6005","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/ijms21176005"],"issn":["1422-0067"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:37, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018859"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=364108","label":"url"}],"paper_title":{"en":"A 10-year analysis of internet search trends of the oral health-seeking behavior of Filipinos","ja":"A 10-year analysis of internet search trends of the oral health-seeking behavior of Filipinos"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"松香 芳三"}]},"publication_date":"2020-07-07","publication_name":{"en":"Poverty & Public Policy","ja":"Poverty & Public Policy"},"volume":"Vol.12","number":"No.2","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1002/pop4.280"],"issn":["1944-2858"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:38, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/32597348","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85087487282&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=366456","label":"url"}],"paper_title":{"en":"Comparative analysis of education, awareness, and knowledge of dentists and physical therapists in the treatment of temporomandibular disorders","ja":"Comparative analysis of education, awareness, and knowledge of dentists and physical therapists in the treatment of temporomandibular disorders"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Ugalde RB"},{"name":"Catibod LD"},{"name":"Macaso JML"},{"name":"Okura Kazuo"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"Ugalde RB"},{"name":"Catibod LD"},{"name":"Macaso JML"},{"name":"大倉 一夫"},{"name":"松香 芳三"}]},"description":{"en":"To compare the education, awareness, and knowledge of Filipino dentists and physical therapists (PTs) in terms of temporomandibular disorders (TMDs). A 30-item structured online questionnaire was given to recruited PTs and dentists from January 2019 to December 2019. Welch's -test was used to compare the education, awareness, and knowledge of health professionals. Brown-Forsythe and Welch ANOVA with Games-Howell post hoc were used to compare test scores across the knowledge components. Of the 620 professionals, 46.67% dentists and 6.38% PTs had training in TMD. Professionals with more years of experience and who had previous TMD training were more aware of TMD management. Both dentists and PTs showed the lowest knowledge in TMD pathophysiology. This study showed high awareness but low education and knowledge of Filipino dentists and PTs in TMD management. Improving the educational curriculum and refining the training given by accredited professional organizations is suggested.","ja":"To compare the education, awareness, and knowledge of Filipino dentists and physical therapists (PTs) in terms of temporomandibular disorders (TMDs). A 30-item structured online questionnaire was given to recruited PTs and dentists from January 2019 to December 2019. Welch's -test was used to compare the education, awareness, and knowledge of health professionals. Brown-Forsythe and Welch ANOVA with Games-Howell post hoc were used to compare test scores across the knowledge components. Of the 620 professionals, 46.67% dentists and 6.38% PTs had training in TMD. Professionals with more years of experience and who had previous TMD training were more aware of TMD management. Both dentists and PTs showed the lowest knowledge in TMD pathophysiology. This study showed high awareness but low education and knowledge of Filipino dentists and PTs in TMD management. Improving the educational curriculum and refining the training given by accredited professional organizations is suggested."},"publication_date":"2020-06-28","publication_name":{"en":"Cranio","ja":"Cranio"},"starting_page":"1","ending_page":"8","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1080/08869634.2020.1786332"],"issn":["2151-0903"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:39, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018860"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=363005","label":"url"}],"paper_title":{"en":"Global interest for health professions education: A geographic and temporal analyses through web search differences from 2010-2019","ja":"Global interest for health professions education: A geographic and temporal analyses through web search differences from 2010-2019"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"松香 芳三"}]},"publication_date":"2020-06-13","publication_name":{"en":"The Internet Journal of Allied Health Sciences and Practice","ja":"The Internet Journal of Allied Health Sciences and Practice"},"volume":"Vol.18","number":"No.3","starting_page":"1","ending_page":"8","languages":["eng"],"referee":true,"identifiers":{"issn":["1540-580X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:40, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/114998","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/32334480","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85084030206&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=364190","label":"url"}],"paper_title":{"en":"Analysis of the Filipinos interest in searching online for oral cancer","ja":"Analysis of the Filipinos interest in searching online for oral cancer"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Esguerra R"},{"name":"Diano LM"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"Esguerra R"},{"name":"Diano LM"},{"name":"松香 芳三"}]},"description":{"en":"This study analyzed the health-seeking behavior of Filipinos through relative search volume in Google Trends using oral cancer, mouth cancer, tongue cancer, gum cancer, and lip cancer as predetermined search terms. Comma-separated values files containing relative search volumes of search trends pertaining to oral cancer from 2009 to 2019 were assessed. Brown-Forsythe one-way ANOVA was used to measure differences of oral cancer between years and among months. Repeated measures two-way ANOVA measured differences among the searches for mouth cancer, tongue cancer, gum cancer, and lip cancer through the years. Time series models were fitted and used to forecast search interests. The results revealed that interests in oral cancer were significantly higher in 2019 (43.75±5.5, p<0.05) compared to 2009 (29.0 ± 6.7). In terms of months, searches were higher in February (45.0 ± 6.6) compared to May (24.8 ± 3.4, p=0.015), June (25.3 ± 4.4, p=0.020), and December (26.5 ± 4.0, p=0.038). Search interests for gum cancer and lip cancer remained significantly lower from 2011 to 2019, and tongue cancer from 2016 to 2018 but approximated mouth cancer in 2019. The forecast shows mouth cancer (31.67%), tongue cancer (23.75%), and lip cancer (3.83%) fluctuating through the year, while gum cancer (8%) will remain steady in 2020. Health-seeking behavior through search trends show an increased interest in oral cancer in 2019 and during February. Search interests will fluctuate in 2020, but at the end of the year will decrease for mouth cancer and tongue cancer, will increase for lip cancer, and will remain steady for gum cancer.","ja":"This study analyzed the health-seeking behavior of Filipinos through relative search volume in Google Trends using oral cancer, mouth cancer, tongue cancer, gum cancer, and lip cancer as predetermined search terms. Comma-separated values files containing relative search volumes of search trends pertaining to oral cancer from 2009 to 2019 were assessed. Brown-Forsythe one-way ANOVA was used to measure differences of oral cancer between years and among months. Repeated measures two-way ANOVA measured differences among the searches for mouth cancer, tongue cancer, gum cancer, and lip cancer through the years. Time series models were fitted and used to forecast search interests. The results revealed that interests in oral cancer were significantly higher in 2019 (43.75±5.5, p<0.05) compared to 2009 (29.0 ± 6.7). In terms of months, searches were higher in February (45.0 ± 6.6) compared to May (24.8 ± 3.4, p=0.015), June (25.3 ± 4.4, p=0.020), and December (26.5 ± 4.0, p=0.038). Search interests for gum cancer and lip cancer remained significantly lower from 2011 to 2019, and tongue cancer from 2016 to 2018 but approximated mouth cancer in 2019. The forecast shows mouth cancer (31.67%), tongue cancer (23.75%), and lip cancer (3.83%) fluctuating through the year, while gum cancer (8%) will remain steady in 2020. Health-seeking behavior through search trends show an increased interest in oral cancer in 2019 and during February. Search interests will fluctuate in 2020, but at the end of the year will decrease for mouth cancer and tongue cancer, will increase for lip cancer, and will remain steady for gum cancer."},"publication_date":"2020-04-01","publication_name":{"en":"Asian Pacific Journal of Cancer Prevention : APJCP","ja":"Asian Pacific Journal of Cancer Prevention : APJCP"},"volume":"Vol.21","number":"No.4","starting_page":"1121","ending_page":"1127","languages":["eng"],"referee":true,"identifiers":{"doi":["10.31557/APJCP.2020.21.4.1121"],"issn":["2476-762X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:41, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018861"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=363091","label":"url"}],"paper_title":{"en":"A descriptive study of the regional and time-point changes in the Filipinos' internet search for tooth decay and toothache","ja":"A descriptive study of the regional and time-point changes in the Filipinos' internet search for tooth decay and toothache"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"松香 芳三"}]},"publication_date":"2020-03","publication_name":{"en":"Philippine Journal of Health Research and Development","ja":"Philippine Journal of Health Research and Development"},"volume":"Vol.24","number":"No.1","starting_page":"39","ending_page":"45","languages":["eng"],"referee":true,"published_paper_type":"scientific_journal"},"priority":"input_data"} line:42, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/114213","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/32015383","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=362695","label":"url"}],"paper_title":{"en":"Three-dimensional periodontal tissue regeneration using a bone-ligament complex cell sheet","ja":"Three-dimensional periodontal tissue regeneration using a bone-ligament complex cell sheet"},"authors":{"en":[{"name":"Raju Resmi"},{"name":"Ohshima Masamitsu"},{"name":"Inoue Miho"},{"name":"Morita Tsuyoshi"},{"name":"Huijiao Yan"},{"name":"Waskitho Arief"},{"name":"Baba Otto"},{"name":"Inoue Masahisa"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"RESMI RAJU"},{"name":"大島 正充"},{"name":"井上 美穂"},{"name":"守田 剛"},{"name":"YAN HUIJIAO"},{"name":"ARIEF WASKITHO"},{"name":"馬場 麻人"},{"name":"Inoue Masahisa"},{"name":"松香 芳三"}]},"description":{"en":"Periodontal tissue is a distinctive tissue structure composed three-dimensionally of cementum, periodontal ligament (PDL) and alveolar bone. Severe periodontal diseases cause fundamental problems for oral function and general health, and conventional dental treatments are insufficient for healing to healthy periodontal tissue. Cell sheet technology has been used in many tissue regenerations, including periodontal tissue, to transplant appropriate stem/progenitor cells for tissue regeneration of a target site as a uniform tissue. However, it is still difficult to construct a three-dimensional structure of complex tissue composed of multiple types of cells, and the transplantation of a single cell sheet cannot sufficiently regenerate a large-scale tissue injury. Here, we fabricated a three-dimensional complex cell sheet composed of a bone-ligament structure by layering PDL cells and osteoblast-like cells on a temperature responsive culture dish. Following ectopic and orthotopic transplantation, only the complex cell sheet group was demonstrated to anatomically regenerate the bone-ligament structure along with the functional connection of PDL-like fibers to the tooth root and alveolar bone. This study represents successful three-dimensional tissue regeneration of a large-scale tissue injury using a bioengineered tissue designed to simulate the anatomical structure.","ja":"Periodontal tissue is a distinctive tissue structure composed three-dimensionally of cementum, periodontal ligament (PDL) and alveolar bone. Severe periodontal diseases cause fundamental problems for oral function and general health, and conventional dental treatments are insufficient for healing to healthy periodontal tissue. Cell sheet technology has been used in many tissue regenerations, including periodontal tissue, to transplant appropriate stem/progenitor cells for tissue regeneration of a target site as a uniform tissue. However, it is still difficult to construct a three-dimensional structure of complex tissue composed of multiple types of cells, and the transplantation of a single cell sheet cannot sufficiently regenerate a large-scale tissue injury. Here, we fabricated a three-dimensional complex cell sheet composed of a bone-ligament structure by layering PDL cells and osteoblast-like cells on a temperature responsive culture dish. Following ectopic and orthotopic transplantation, only the complex cell sheet group was demonstrated to anatomically regenerate the bone-ligament structure along with the functional connection of PDL-like fibers to the tooth root and alveolar bone. This study represents successful three-dimensional tissue regeneration of a large-scale tissue injury using a bioengineered tissue designed to simulate the anatomical structure."},"publication_date":"2020-02-03","publication_name":{"en":"Scientific Reports","ja":"Scientific Reports"},"volume":"Vol.10","number":"No.1","starting_page":"1656","ending_page":"1656","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1038/s41598-020-58222-0"],"issn":["2045-2322"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:43, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/31746005","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=360753","label":"url"}],"paper_title":{"en":"Association of masticatory muscle activity with sleep arousal and other concomitant movements during sleep","ja":"Association of masticatory muscle activity with sleep arousal and other concomitant movements during sleep"},"authors":{"en":[{"name":"Miki Haruna"},{"name":"Minakuchi Hajime"},{"name":"Miyagi Mayu"},{"name":"Hara Emilio Satoshi"},{"name":"Shigemoto Shuji"},{"name":"Suzuki Yoshitaka"},{"name":"Maekawa Kenji"},{"name":"Matsuka Yoshizo"},{"name":"Clark GT"},{"name":"Kuboki Takuo"}],"ja":[{"name":"Miki Haruna"},{"name":"Minakuchi Hajime"},{"name":"宮城 麻友"},{"name":"Hara Emilio Satoshi"},{"name":"重本 修伺"},{"name":"鈴木 善貴"},{"name":"Maekawa Kenji"},{"name":"松香 芳三"},{"name":"Clark GT"},{"name":"Kuboki Takuo"}]},"description":{"en":"This study aims to verify the associations among sleep bruxism (SB), sleep arousal (SA) and concurrent body movements. Subjects underwent a standard overnight polysomnography test and audio-video recordings. Sleep quality was evaluated according to the Rechtschaffen and Kales criteria, while SA was determined as per the American Sleep Disorders Association criteria. Analyses were performed by an external institution after masking of the subjects' information. SB was assessed based on the presence/absence of rhythmic masticatory muscle activity (RMMA) episodes, which were identified by using electromyography of the masseter muscle. The observed simultaneous movements included lower leg movement (LLM), swallowing, face scratching, head movement, body movement, eye blinking, coughing, licking, sighing, body scratching, lip sucking, somniloquy and yawning. The LLM was determined visually, as well as through an increase in the tibialis electromyogram signal. Other movements were visually assessed using audio-video recordings. The incidences of all the simultaneous movements were compared between RMMA with intercurrent SA (SAwRMMA; RMMA episode derived from a masseter electromyogram showing more than 10% of maximum voluntary contraction) and SA without RMMA (SAw/oRMMA). Fourteen subjects were included in this study (females/males: 4/10, mean age: 31.5 ± 5.7 years). Among these, LLM, swallowing, body movement, licking, body scratching and lip sucking were frequently observed in SAwRMMA episodes than in SAw/oRMMA episodes, significantly. However, the non-specific simultaneous movements were higher observed in SAw/oRMMA episodes than that in SAwRMMA. Our results suggest that SB is concurrently activated with LLM in relation to arousal.","ja":"This study aims to verify the associations among sleep bruxism (SB), sleep arousal (SA) and concurrent body movements. Subjects underwent a standard overnight polysomnography test and audio-video recordings. Sleep quality was evaluated according to the Rechtschaffen and Kales criteria, while SA was determined as per the American Sleep Disorders Association criteria. Analyses were performed by an external institution after masking of the subjects' information. SB was assessed based on the presence/absence of rhythmic masticatory muscle activity (RMMA) episodes, which were identified by using electromyography of the masseter muscle. The observed simultaneous movements included lower leg movement (LLM), swallowing, face scratching, head movement, body movement, eye blinking, coughing, licking, sighing, body scratching, lip sucking, somniloquy and yawning. The LLM was determined visually, as well as through an increase in the tibialis electromyogram signal. Other movements were visually assessed using audio-video recordings. The incidences of all the simultaneous movements were compared between RMMA with intercurrent SA (SAwRMMA; RMMA episode derived from a masseter electromyogram showing more than 10% of maximum voluntary contraction) and SA without RMMA (SAw/oRMMA). Fourteen subjects were included in this study (females/males: 4/10, mean age: 31.5 ± 5.7 years). Among these, LLM, swallowing, body movement, licking, body scratching and lip sucking were frequently observed in SAwRMMA episodes than in SAw/oRMMA episodes, significantly. However, the non-specific simultaneous movements were higher observed in SAw/oRMMA episodes than that in SAwRMMA. Our results suggest that SB is concurrently activated with LLM in relation to arousal."},"publication_date":"2020-02","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.47","number":"No.3","starting_page":"281","ending_page":"288","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/joor.12913"],"issn":["1365-2842"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:44, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/114079","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/31785264","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85076002926&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=360990","label":"url"}],"paper_title":{"en":"The role of chemical transmitters in neuron-glia interaction and pain in sensory ganglion","ja":"The role of chemical transmitters in neuron-glia interaction and pain in sensory ganglion"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Afroz S"},{"name":"Dalanon Junhel"},{"name":"Iwasa Takuma"},{"name":"Waskitho Arief"},{"name":"Ohshima Masamitsu"}],"ja":[{"name":"松香 芳三"},{"name":"SHAISTA AFROZ"},{"name":"Dalanon Junhel Casinillo"},{"name":"岩浅 匠真"},{"name":"ARIEF WASKITHO"},{"name":"大島 正充"}]},"description":{"en":"Neuropathic pain (NP) develops because of damage to the peripheral or central nervous system. It results in the hyperalgesia and allodynia. In the recent years, various researchers have studied the involvement of neuro-immune system in causing persistence of pain. The absence of synaptic contacts in the sensory ganglion makes them distinctive in terms of pain related signalling. In sensory ganglia, the neurotransmitters or the other modulators such as inflammatory substances produced by the ganglion cells, because of an injury, are responsible for the cross-excitation between neurons and neuron-glial interaction, thus affecting chemical transmission. This chemical transmission is considered mainly responsible for the chronicity and the persistent nature of neuropathic pain. This review examines the pain signalling due to neurotransmitter or cytokine release within the sensory ganglia. The specific areas focused on include: 1) the role of neurotransmitters released from the somata of sensory neurons in pain, 2) neuron-glia interaction and 3) role of cytokines in neuromodulation and pain.","ja":"Neuropathic pain (NP) develops because of damage to the peripheral or central nervous system. It results in the hyperalgesia and allodynia. In the recent years, various researchers have studied the involvement of neuro-immune system in causing persistence of pain. The absence of synaptic contacts in the sensory ganglion makes them distinctive in terms of pain related signalling. In sensory ganglia, the neurotransmitters or the other modulators such as inflammatory substances produced by the ganglion cells, because of an injury, are responsible for the cross-excitation between neurons and neuron-glial interaction, thus affecting chemical transmission. This chemical transmission is considered mainly responsible for the chronicity and the persistent nature of neuropathic pain. This review examines the pain signalling due to neurotransmitter or cytokine release within the sensory ganglia. The specific areas focused on include: 1) the role of neurotransmitters released from the somata of sensory neurons in pain, 2) neuron-glia interaction and 3) role of cytokines in neuromodulation and pain."},"publication_date":"2020-01","publication_name":{"en":"Neuroscience and Biobehavioral Reviews","ja":"Neuroscience and Biobehavioral Reviews"},"volume":"Vol.108","starting_page":"393","ending_page":"399","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.neubiorev.2019.11.019"],"issn":["1873-7528"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:45, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018862"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=366310","label":"url"}],"paper_title":{"en":"Infection control in short-term dental missions in Cebu, Philippines","ja":"Infection control in short-term dental missions in Cebu, Philippines"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Ibon MA"},{"name":"Bustillo JL"},{"name":"Buynay J"},{"name":"Cabusao JD"},{"name":"Sarmiento H"},{"name":"Tormis SM"},{"name":"Belarmino MP"},{"name":"Esguerra R"},{"name":"Docor R"},{"name":"Yoshihara Yasutomo"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"Ibon MA"},{"name":"Bustillo JL"},{"name":"Buynay J"},{"name":"Cabusao JD"},{"name":"Sarmiento H"},{"name":"Tormis SM"},{"name":"Belarmino MP"},{"name":"Esguerra R"},{"name":"Docor R"},{"name":"吉原 靖智"},{"name":"松香 芳三"}]},"publication_date":"2019-12","publication_name":{"en":"The Journal of the Philippine Dental Association","ja":"The Journal of the Philippine Dental Association"},"volume":"Vol.66","number":"No.2","starting_page":"7","ending_page":"12","languages":["eng"],"referee":true,"identifiers":{"issn":["0031-7497"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:46, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=340199","label":"url"}],"paper_title":{"en":"The evolution of dental education in the Philippines","ja":"The evolution of dental education in the Philippines"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"松香 芳三"}]},"publication_date":"2019-09","publication_name":{"en":"Health Professions Education","ja":"Health Professions Education"},"volume":"Vol.5","number":"No.3","starting_page":"172","ending_page":"176","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.hpe.2018.07.001"],"issn":["2452-3011"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:47, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018863"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=360105","label":"url"}],"paper_title":{"en":"Proposal of functional landmark for determining occlusal plane","ja":"Proposal of functional landmark for determining occlusal plane"},"authors":{"en":[{"name":"Takahiro Ito"},{"name":"Shigemoto Shuji"},{"name":"Yuko Shigeta"},{"name":"Matsuka Yoshizo"},{"name":"Takumi Ogawa"}],"ja":[{"name":"Takahiro Ito"},{"name":"重本 修伺"},{"name":"Yuko Shigeta"},{"name":"松香 芳三"},{"name":"Takumi Ogawa"}]},"publication_date":"2019-09-30","publication_name":{"en":"The Journal of Japanese Society of Stomatognathic Function","ja":"The Journal of Japanese Society of Stomatognathic Function"},"volume":"Vol.26","number":"No.1","starting_page":"1","ending_page":"7","languages":["eng"],"referee":true,"identifiers":{"issn":["1340-9085"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:48, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/113686","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=350008","label":"url"}],"paper_title":{"en":"IL-10 and CXCL2 in trigeminal ganglia in neuropathic pain","ja":"IL-10 and CXCL2 in trigeminal ganglia in neuropathic pain"},"authors":{"en":[{"name":"Iwasa Takuma"},{"name":"Afroz S"},{"name":"Inoue Miho"},{"name":"Arakaki Rieko"},{"name":"Ohshima Masamitsu"},{"name":"Raju R"},{"name":"Waskitho Arief"},{"name":"Masahisa Inoue"},{"name":"Baba Otto"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"岩浅 匠真"},{"name":"SHAISTA AFROZ"},{"name":"井上 美穂"},{"name":"新垣 理恵子"},{"name":"大島 正充"},{"name":"RESMI RAJU"},{"name":"ARIEF WASKITHO"},{"name":"Masahisa Inoue"},{"name":"馬場 麻人"},{"name":"松香 芳三"}]},"publication_date":"2019-06-11","publication_name":{"en":"Neuroscience Letters","ja":"Neuroscience Letters"},"volume":"Vol.703","starting_page":"132","ending_page":"138","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.neulet.2019.03.031"],"issn":["0304-3940"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:49, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018864"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=351815","label":"url"}],"paper_title":{"en":"Neuropathic pain: the evidence behind the facts","ja":"Neuropathic pain: the evidence behind the facts"},"authors":{"en":[{"name":"Padilla M"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Padilla M"},{"name":"松香 芳三"}]},"publication_date":"2019-05","publication_name":{"en":"Revista iDental, ULACIT-Costa Rica","ja":"Revista iDental, ULACIT-Costa Rica"},"volume":"Vol.11","number":"No.1","referee":true,"published_paper_type":"scientific_journal"},"priority":"input_data"} line:50, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/30664815","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85061807355&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=349048","label":"url"}],"paper_title":{"en":"The effects of exercise therapy on painful temporomandibular disorders","ja":"The effects of exercise therapy on painful temporomandibular disorders"},"authors":{"en":[{"name":"Shimada Akiko"},{"name":"Ishigaki Shoichi"},{"name":"Matsuka Yoshizo"},{"name":"Komiyama Osamu"},{"name":"Torisu T"},{"name":"Oono Yoko"},{"name":"Sato Hitoshi"},{"name":"Naganawa Takuya"},{"name":"Mine Atsushi"},{"name":"Yamazaki Yoko"},{"name":"Okura Kazuo"},{"name":"Sakuma Yasushi"},{"name":"Sasaki Keiichi"}],"ja":[{"name":"Shimada Akiko"},{"name":"Ishigaki Shoichi"},{"name":"松香 芳三"},{"name":"Komiyama Osamu"},{"name":"Torisu T"},{"name":"Oono Yoko"},{"name":"Sato Hitoshi"},{"name":"Naganawa Takuya"},{"name":"Mine Atsushi"},{"name":"Yamazaki Yoko"},{"name":"大倉 一夫"},{"name":"Sakuma Yasushi"},{"name":"Sasaki Keiichi"}]},"publication_date":"2019-05","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.46","number":"No.5","starting_page":"475","ending_page":"481","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/joor.12770"],"issn":["1365-2842"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:51, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018865"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/113372","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85065527448&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=354302","label":"url"}],"paper_title":{"en":"Analysis of Bone Marrow-derived Mesenchymal Stem Cell Kinetics after Short-term Stimulation with Tumor Necrosis Factor-α (TNF-α)","ja":"Analysis of Bone Marrow-derived Mesenchymal Stem Cell Kinetics after Short-term Stimulation with Tumor Necrosis Factor-α (TNF-α)"},"authors":{"en":[{"name":"Naritani Mio"},{"name":"Inoue Miho"},{"name":"Raju Resmi"},{"name":"Miyagi Mayu"},{"name":"Ohshima Masamitsu"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"成谷 美緒"},{"name":"井上 美穂"},{"name":"RESMI RAJU"},{"name":"宮城 麻友"},{"name":"大島 正充"},{"name":"松香 芳三"}]},"publication_date":"2019-04-24","publication_name":{"en":"Journal of Hard Tissue Biology","ja":"Journal of Hard Tissue Biology"},"volume":"Vol.28","number":"No.2","starting_page":"99","ending_page":"108","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2485/jhtb.28.99"],"issn":["1880-828X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:52, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018866"},"force":{"see_also":[{"@id":"https://cir.nii.ac.jp/crid/1390845713064069760/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=350166","label":"url"}],"paper_title":{"en":"一次性および二次性舌痛症患者における睡眠障害の検討—睡眠質問票を用いた調査—","ja":"一次性および二次性舌痛症患者における睡眠障害の検討—睡眠質問票を用いた調査—"},"authors":{"en":[{"name":"Abe Susumu"},{"name":"Momota Yukihiro"},{"name":"Matsuka Yoshizo"},{"name":"Okawa Toshinori"},{"name":"Horikawa Eriko"},{"name":"Hayama Rika"},{"name":"Okura Kazuo"},{"name":"Kawano Fumiaki"}],"ja":[{"name":"安陪 晋"},{"name":"桃田 幸弘"},{"name":"松香 芳三"},{"name":"大川 敏永"},{"name":"堀川 恵理子"},{"name":"葉山 莉香"},{"name":"大倉 一夫"},{"name":"河野 文昭"}]},"publication_date":"2019-04-12","publication_name":{"en":"Japanese Journal of Orofacial Pain","ja":"日本口腔顔面痛学会雑誌"},"volume":"Vol.10","number":"No.1","starting_page":"9","ending_page":"16","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11264/jjop.10.9"],"issn":["1882-9333"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:53, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018867"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/114270","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390564238091828480/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=363015","label":"url"}],"paper_title":{"en":"アンケート調査による顎関節症の病態分類(2013年)の利用状況","ja":"アンケート調査による顎関節症の病態分類(2013年)の利用状況"},"authors":{"en":[{"name":"檀上 敦"},{"name":"覚道 健治"},{"name":"久保田英 朗"},{"name":"矢谷 博文"},{"name":"築山 能大"},{"name":"有馬 太郎"},{"name":"Matsuka Yoshizo"},{"name":"山下 佳雄"}],"ja":[{"name":"檀上 敦"},{"name":"覚道 健治"},{"name":"久保田英 朗"},{"name":"矢谷 博文"},{"name":"築山 能大"},{"name":"有馬 太郎"},{"name":"松香 芳三"},{"name":"山下 佳雄"}]},"publication_date":"2019-03","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.31","number":"No.1","starting_page":"16","ending_page":"23","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11246/gakukansetsu.31.16"],"issn":["1884-4308"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:54, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/113013","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390564238075555456/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=342108","label":"url"}],"paper_title":{"en":"Quality of life and job satisfaction among female dentists in Japan","ja":"Quality of life and job satisfaction among female dentists in Japan"},"authors":{"en":[{"name":"Hayama Rika"},{"name":"Kanemitsu Yukari"},{"name":"Goda Chisato"},{"name":"Abe Susumu"},{"name":"Okura Kazuo"},{"name":"Afroz Shaista"},{"name":"Goto Nami"},{"name":"Raju Resmi"},{"name":"Dalanon Junhel"},{"name":"Ohshima Masamitsu"},{"name":"Rodis Omar"},{"name":"Okayama Yoshihiro"},{"name":"Kawano Fumiaki"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"葉山 莉香"},{"name":"金光 侑香里"},{"name":"合田 千里"},{"name":"安陪 晋"},{"name":"大倉 一夫"},{"name":"SHAISTA AFROZ"},{"name":"Goto Nami"},{"name":"RESMI RAJU"},{"name":"Dalanon Junhel Casinillo"},{"name":"大島 正充"},{"name":"ロディス オマー"},{"name":"Okayama Yoshihiro"},{"name":"河野 文昭"},{"name":"松香 芳三"}]},"publication_date":"2019-02-12","publication_name":{"en":"Journal of Oral Health and Biosciences","ja":"Journal of Oral Health and Biosciences"},"volume":"Vol.31","number":"No.2","starting_page":"79","ending_page":"86","languages":["eng"],"referee":true,"identifiers":{"doi":["10.20738/johb.31.2_79"],"issn":["2188-7888"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:55, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/113687","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/30736422","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85061270594&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=349406","label":"url"}],"paper_title":{"en":"CGRP induces differential regulation of cytokines from satellite glial cells in trigeminal ganglia and orofacial nociception","ja":"CGRP induces differential regulation of cytokines from satellite glial cells in trigeminal ganglia and orofacial nociception"},"authors":{"en":[{"name":"Afroz S"},{"name":"Arakaki Rieko"},{"name":"Iwasa Takuma"},{"name":"Ohshima Masamitsu"},{"name":"Hosoki Maki"},{"name":"Inoue Miho"},{"name":"Baba Otto"},{"name":"Okayama Yoshihiro"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"SHAISTA AFROZ"},{"name":"新垣 理恵子"},{"name":"岩浅 匠真"},{"name":"大島 正充"},{"name":"細木 眞紀"},{"name":"井上 美穂"},{"name":"馬場 麻人"},{"name":"Okayama Yoshihiro"},{"name":"松香 芳三"}]},"description":{"en":"Neuron-glia interactions contribute to pain initiation and sustainment. Intra-ganglionic (IG) secretion of calcitonin gene-related peptide (CGRP) in the trigeminal ganglion (TG) modulates pain transmission through neuron-glia signaling, contributing to various orofacial pain conditions. The present study aimed to investigate the role of satellite glial cells (SGC) in TG in causing cytokine-related orofacial nociception in response to IG administration of CGRP. For that purpose, CGRP alone (10 μL of 10 M), Minocycline (5 μL containing 10 μg) followed by CGRP with one hour gap (Min + CGRP) were administered directly inside the TG in independent experiments. Rats were evaluated for thermal hyperalgesia at 6 and 24 h post-injection using an operant orofacial pain assessment device (OPAD) at three temperatures (37, 45 and 10 °C). Quantitative real-time PCR was performed to evaluate the mRNA expression of IL-1β, IL-6, TNF-α, IL-1 receptor antagonist (IL-1RA), sodium channel 1.7 (NaV 1.7, for assessment of neuronal activation) and glial fibrillary acidic protein (GFAP, a marker of glial activation). The cytokines released in culture media from purified glial cells were evaluated using antibody cytokine array. IG CGRP caused heat hyperalgesia between 6-24 h (paired- test, < 0.05). Between 1 to 6 h the mRNA and protein expressions of GFAP was increased in parallel with an increase in the mRNA expression of pro-inflammatory cytokines IL-1β and anti-inflammatory cytokine IL-1RA and NaV1.7 (one-way ANOVA followed by Dunnett's post hoc test, < 0.05). To investigate whether glial inhibition is useful to prevent nociception symptoms, Minocycline (glial inhibitor) was administered IG 1 h before CGRP injection. Minocycline reversed CGRP-induced thermal nociception, glial activity, and down-regulated IL-1β and IL-6 cytokines significantly at 6 h (-test, < 0.05). Purified glial cells in culture showed an increase in release of 20 cytokines after stimulation with CGRP. Our findings demonstrate that SGCs in the sensory ganglia contribute to the occurrence of pain via cytokine expression and that glial inhibition can effectively control the development of nociception.","ja":"Neuron-glia interactions contribute to pain initiation and sustainment. Intra-ganglionic (IG) secretion of calcitonin gene-related peptide (CGRP) in the trigeminal ganglion (TG) modulates pain transmission through neuron-glia signaling, contributing to various orofacial pain conditions. The present study aimed to investigate the role of satellite glial cells (SGC) in TG in causing cytokine-related orofacial nociception in response to IG administration of CGRP. For that purpose, CGRP alone (10 μL of 10 M), Minocycline (5 μL containing 10 μg) followed by CGRP with one hour gap (Min + CGRP) were administered directly inside the TG in independent experiments. Rats were evaluated for thermal hyperalgesia at 6 and 24 h post-injection using an operant orofacial pain assessment device (OPAD) at three temperatures (37, 45 and 10 °C). Quantitative real-time PCR was performed to evaluate the mRNA expression of IL-1β, IL-6, TNF-α, IL-1 receptor antagonist (IL-1RA), sodium channel 1.7 (NaV 1.7, for assessment of neuronal activation) and glial fibrillary acidic protein (GFAP, a marker of glial activation). The cytokines released in culture media from purified glial cells were evaluated using antibody cytokine array. IG CGRP caused heat hyperalgesia between 6-24 h (paired- test, < 0.05). Between 1 to 6 h the mRNA and protein expressions of GFAP was increased in parallel with an increase in the mRNA expression of pro-inflammatory cytokines IL-1β and anti-inflammatory cytokine IL-1RA and NaV1.7 (one-way ANOVA followed by Dunnett's post hoc test, < 0.05). To investigate whether glial inhibition is useful to prevent nociception symptoms, Minocycline (glial inhibitor) was administered IG 1 h before CGRP injection. Minocycline reversed CGRP-induced thermal nociception, glial activity, and down-regulated IL-1β and IL-6 cytokines significantly at 6 h (-test, < 0.05). Purified glial cells in culture showed an increase in release of 20 cytokines after stimulation with CGRP. Our findings demonstrate that SGCs in the sensory ganglia contribute to the occurrence of pain via cytokine expression and that glial inhibition can effectively control the development of nociception."},"publication_date":"2019-02-01","publication_name":{"en":"International Journal of Molecular Sciences","ja":"International Journal of Molecular Sciences"},"volume":"Vol.20","number":"No.3","starting_page":"711","ending_page":"711","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/ijms20030711"],"issn":["1422-0067"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:56, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018868"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=351872","label":"url"}],"paper_title":{"en":"The Cebuano mothers willingness to pay for dental healthcare","ja":"The Cebuano mothers willingness to pay for dental healthcare"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Diano LM"},{"name":"Esguerra R"},{"name":"Belarmino MP"},{"name":"Docor R"},{"name":"Rodis Omar"},{"name":"Locsin Rozzano"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"Diano LM"},{"name":"Esguerra R"},{"name":"Belarmino MP"},{"name":"Docor R"},{"name":"ロディス オマー"},{"name":"ロクシン ロザーノ"},{"name":"松香 芳三"}]},"publication_date":"2019-01","publication_name":{"en":"The Journal of the Philippine Dental Association","ja":"The Journal of the Philippine Dental Association"},"volume":"Vol.65","number":"No.2","starting_page":"33","ending_page":"37","languages":["eng"],"referee":true,"identifiers":{"issn":["0031-7497"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:57, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018869"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116328","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=349238","label":"url"}],"paper_title":{"en":"咬合不全を伴った重度変形性顎関節症症例","ja":"咬合不全を伴った重度変形性顎関節症症例"},"authors":{"en":[{"name":"Hosoki Maki"},{"name":"Nishigawa Keisuke"},{"name":"Maeda Naoki"},{"name":"Hosoki Hidehiko"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"細木 眞紀"},{"name":"西川 啓介"},{"name":"前田 直樹"},{"name":"細木 秀彦"},{"name":"松香 芳三"}]},"publication_date":"2018-12-20","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.30","number":"No.3","starting_page":"261","ending_page":"265","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11246/gakukansetsu.30.261"],"issn":["1884-4308"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:58, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018870"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=349237","label":"url"}],"paper_title":{"en":"特別養護老人ホーム入所者における顎関節脱臼の実態調査","ja":"特別養護老人ホーム入所者における顎関節脱臼の実態調査"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"西山 暁"},{"name":"湯浅 秀道"},{"name":"水口 一"},{"name":"髙野 直久"},{"name":"羽毛田 匡"},{"name":"Suzuki Yoshitaka"},{"name":"Dalanon Junhel"},{"name":"久保田 英朗"},{"name":"杉崎 正志"},{"name":"木野 孔司"},{"name":"古谷野 潔"}],"ja":[{"name":"松香 芳三"},{"name":"西山 暁"},{"name":"湯浅 秀道"},{"name":"水口 一"},{"name":"髙野 直久"},{"name":"羽毛田 匡"},{"name":"鈴木 善貴"},{"name":"Dalanon Junhel"},{"name":"久保田 英朗"},{"name":"杉崎 正志"},{"name":"木野 孔司"},{"name":"古谷野 潔"}]},"publication_date":"2018-12-20","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.30","number":"No.3","starting_page":"249","ending_page":"254","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11246/gakukansetsu.30.249"],"issn":["1884-4308"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:59, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/112948","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/29673741","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85045460070&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=336785","label":"url"}],"paper_title":{"en":"Cross-sectional observational study exploring clinical risk of titanium allergy caused by dental implants","ja":"Cross-sectional observational study exploring clinical risk of titanium allergy caused by dental implants"},"authors":{"en":[{"name":"Hosoki Maki"},{"name":"Nishigawa Keisuke"},{"name":"Tajima Toyoko"},{"name":"Miyagi Mayu"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"細木 眞紀"},{"name":"西川 啓介"},{"name":"田島 登誉子"},{"name":"宮城 麻友"},{"name":"松香 芳三"}]},"description":{"en":"Studies have reported cases of metal allergy caused by titanium-containing materials. We wished to clarify the relationship between titanium allergy and dental implants by describing patients who suffered allergic symptoms after they had received such implants. A total of 270 patients who visited a Dental Metal Allergy Clinic at Tokushima University Hospital from April 2010 to March 2014 were the study cohort. Patch testing with 28 types of metal allergens (including four titanium allergens) was undertaken for patients. A total of 217 patients (80.4 %) exhibited allergy-positive reactions to at least one type of metal allergen. Mercury, palladium, chromium and nickel exhibited a higher prevalence of allergy-positive reactions than other metals. Sixteen patients visited our clinic suffering allergic symptoms after receiving dental implants. Eleven of those patients exhibited allergy-positive reactions for any of the metal allergens, and 4 of these patients had allergy-positive reactions against titanium allergens. The total number of allergy-positive reactions for titanium allergens among all 270 patients was 17 (6.3 %). No patient exhibited a positive reaction only for the titanium allergen. The prevalence of allergy-positive reactions for titanium allergens was lower than for other metal allergens. We suggest examination of pre-implant patients who have a history of hypersensitivity reactions to metals.","ja":"Studies have reported cases of metal allergy caused by titanium-containing materials. We wished to clarify the relationship between titanium allergy and dental implants by describing patients who suffered allergic symptoms after they had received such implants. A total of 270 patients who visited a Dental Metal Allergy Clinic at Tokushima University Hospital from April 2010 to March 2014 were the study cohort. Patch testing with 28 types of metal allergens (including four titanium allergens) was undertaken for patients. A total of 217 patients (80.4 %) exhibited allergy-positive reactions to at least one type of metal allergen. Mercury, palladium, chromium and nickel exhibited a higher prevalence of allergy-positive reactions than other metals. Sixteen patients visited our clinic suffering allergic symptoms after receiving dental implants. Eleven of those patients exhibited allergy-positive reactions for any of the metal allergens, and 4 of these patients had allergy-positive reactions against titanium allergens. The total number of allergy-positive reactions for titanium allergens among all 270 patients was 17 (6.3 %). No patient exhibited a positive reaction only for the titanium allergen. The prevalence of allergy-positive reactions for titanium allergens was lower than for other metal allergens. We suggest examination of pre-implant patients who have a history of hypersensitivity reactions to metals."},"publication_date":"2018-10","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.62","number":"No.4","starting_page":"426","ending_page":"431","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2018.03.003"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:60, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=365444","label":"url"}],"paper_title":{"en":"Investigation of behavioural factors which vary occlusal contact in Japanese dental students","ja":"Investigation of behavioural factors which vary occlusal contact in Japanese dental students"},"authors":{"en":[{"name":"Hayama Rika"},{"name":"Suzuki Yoshitaka"},{"name":"Nishigawa Keisuke"},{"name":"Okura Kazuo"},{"name":"Miyagi Mayu"},{"name":"Abe Susumu"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"葉山 莉香"},{"name":"鈴木 善貴"},{"name":"西川 啓介"},{"name":"大倉 一夫"},{"name":"宮城 麻友"},{"name":"安陪 晋"},{"name":"松香 芳三"}]},"publication_date":"2018-09","publication_name":{"en":"The Journal of Japanese Society of Stomatognathic Function","ja":"The Journal of Japanese Society of Stomatognathic Function"},"volume":"Vol.25","number":"No.1","starting_page":"1","ending_page":"9","languages":["eng"],"referee":true,"identifiers":{"issn":["1340-9085"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:61, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/30153093","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85053259474&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=360754","label":"url"}],"paper_title":{"en":"Posterior disc displacement of the temporomandibular joint -a rare case report","ja":"Posterior disc displacement of the temporomandibular joint -a rare case report"},"authors":{"en":[{"name":"Afroz S"},{"name":"Naritani Mio"},{"name":"Hosoki Hidehiko"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"SHAISTA AFROZ"},{"name":"成谷 美緒"},{"name":"細木 秀彦"},{"name":"松香 芳三"}]},"description":{"en":"Posterior disc displacement (PDD) of the temporomandibular joint (TMJ) is quite rare. The normal position of a disc is slightly anterior to the condyle, so the chances of disc displacement to the posterior direction are low. A 71-year-old Japanese female reported with a chief complaint of lack of occlusion on the right-side molar teeth. Clinical examination revealed lack of occlusal contact in the right posterior region, nearly normal range of mouth opening (41.0 mm), masseter muscle tenderness, and deviation to the left on opening. MRI of the right TMJ showed PDD in both the open- and closed-mouth position and joint effusion. Conservative treatment with a non-steroidal anti-inflammatory drug, stretch exercise with fingers, and stabilization splint improved symptoms for 9 months. Conservative treatment was effective in managing the patient. A follow-up for 9 months with a repeat MRI was undertaken to monitor the progress.","ja":"Posterior disc displacement (PDD) of the temporomandibular joint (TMJ) is quite rare. The normal position of a disc is slightly anterior to the condyle, so the chances of disc displacement to the posterior direction are low. A 71-year-old Japanese female reported with a chief complaint of lack of occlusion on the right-side molar teeth. Clinical examination revealed lack of occlusal contact in the right posterior region, nearly normal range of mouth opening (41.0 mm), masseter muscle tenderness, and deviation to the left on opening. MRI of the right TMJ showed PDD in both the open- and closed-mouth position and joint effusion. Conservative treatment with a non-steroidal anti-inflammatory drug, stretch exercise with fingers, and stabilization splint improved symptoms for 9 months. Conservative treatment was effective in managing the patient. A follow-up for 9 months with a repeat MRI was undertaken to monitor the progress."},"publication_date":"2018-08-28","publication_name":{"en":"Cranio","ja":"Cranio"},"volume":"Vol.38","number":"No.4","starting_page":"273","ending_page":"278","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1080/08869634.2018.1509823"],"issn":["2151-0903"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:62, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/112947","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/30349710","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=340319","label":"url"}],"paper_title":{"en":"Metal allergy patient treated by titanium implant denture: A case report with at least 4-year follow-up","ja":"Metal allergy patient treated by titanium implant denture: A case report with at least 4-year follow-up"},"authors":{"en":[{"name":"Yan Huijiao"},{"name":"Afroz S"},{"name":"Dalanon Junhel"},{"name":"Goto Nami"},{"name":"Hosoki Maki"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"閻 会嬌"},{"name":"SHAISTA AFROZ"},{"name":"Dalanon Junhel Casinillo"},{"name":"Goto Nami"},{"name":"細木 眞紀"},{"name":"松香 芳三"}]},"description":{"en":"Patch testing with metal reagents was positive on female patient with history of metal hypersensitivity after dental treatment. All of the dental restorations with metal components were removed, and subsequent oral rehabilitation utilizing dental implants and metal-free prostheses was carried out. The treatments alleviate the presenting signs and symptoms.","ja":"Patch testing with metal reagents was positive on female patient with history of metal hypersensitivity after dental treatment. All of the dental restorations with metal components were removed, and subsequent oral rehabilitation utilizing dental implants and metal-free prostheses was carried out. The treatments alleviate the presenting signs and symptoms."},"publication_date":"2018-08-28","publication_name":{"en":"Clinical Case Reports","ja":"Clinical Case Reports"},"volume":"Vol.6","number":"No.10","starting_page":"1972","ending_page":"1977","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1002/ccr3.1753"],"issn":["2050-0904"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:63, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116070","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/29697716","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=335174","label":"url"}],"paper_title":{"en":"Prevalence of posterior disc displacement of the temporomandibular joint in patients with temporomandibular disorders: a systematic review with meta-analysis","ja":"Prevalence of posterior disc displacement of the temporomandibular joint in patients with temporomandibular disorders: a systematic review with meta-analysis"},"authors":{"en":[{"name":"Afroz Shaista"},{"name":"Naritani Mio"},{"name":"Hosoki Hidehiko"},{"name":"Takechi Kenshi"},{"name":"Okayama Yoshihiro"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"SHAISTA AFROZ"},{"name":"成谷 美緒"},{"name":"細木 秀彦"},{"name":"武智 研志"},{"name":"Okayama Yoshihiro"},{"name":"松香 芳三"}]},"description":{"en":"To assess the prevalence of posterior disc displacement (PDD) in patients with temporomandibular disorders (TMD) through a systematic review of the literature and meta-analysis, as well as to assess features associated with PDD such as chief complaint, signs and symptoms, morphologic condyle and disc alterations, and PDD management. A systematic literature search was performed in the US National Library of Medicine's PubMed/MEDLINE and Cochrane Library databases to identify all peer-reviewed, English-language manuscripts related to PDD. A critical appraisal checklist provided by the Joanna Briggs Institute for studies reporting prevalence data was used to assess the quality of the included manuscripts. A meta-analysis was conducted using software MetaXL 5.3 (EpiGear International Pty Ltd) add-in for Microsoft Excel. Pooled prevalence and 95% confidence intervals (CIs) were calculated using the software. Heterogeneity of the included studies was assessed using the Higgins I test and Cochran's Q (with P value; < .05 was considered significant). A total of 21 articles were selected for qualitative data synthesis: 2 case reports, 14 observational studies, and 5 studies that reported PDD in various conditions. Quantitative data analysis was performed for the 14 observational studies, of which 13 reported prevalence with respect to the number of joints affected and 9 reported prevalence with respect to the number of patients affected. The overall pooled prevalence of PDD for the number of joints affected was 0.7% (95% CI: 0.005 to 0.008). The pooled prevalence of PDD for the number of patients was 0.9% (95% CI: 0.007 to 0.011). PDD was found to be associated with osseous changes, including changes in the morphology of the condyle, disc, and articular eminence; osseous abnormalities (erosion, osteophytes); and joint effusion. This meta-analysis showed a very low prevalence rate of PDD in TMD patients. The limited literature did not allow conclusions to be drawn about the PDD-related features.","ja":"To assess the prevalence of posterior disc displacement (PDD) in patients with temporomandibular disorders (TMD) through a systematic review of the literature and meta-analysis, as well as to assess features associated with PDD such as chief complaint, signs and symptoms, morphologic condyle and disc alterations, and PDD management. A systematic literature search was performed in the US National Library of Medicine's PubMed/MEDLINE and Cochrane Library databases to identify all peer-reviewed, English-language manuscripts related to PDD. A critical appraisal checklist provided by the Joanna Briggs Institute for studies reporting prevalence data was used to assess the quality of the included manuscripts. A meta-analysis was conducted using software MetaXL 5.3 (EpiGear International Pty Ltd) add-in for Microsoft Excel. Pooled prevalence and 95% confidence intervals (CIs) were calculated using the software. Heterogeneity of the included studies was assessed using the Higgins I test and Cochran's Q (with P value; < .05 was considered significant). A total of 21 articles were selected for qualitative data synthesis: 2 case reports, 14 observational studies, and 5 studies that reported PDD in various conditions. Quantitative data analysis was performed for the 14 observational studies, of which 13 reported prevalence with respect to the number of joints affected and 9 reported prevalence with respect to the number of patients affected. The overall pooled prevalence of PDD for the number of joints affected was 0.7% (95% CI: 0.005 to 0.008). The pooled prevalence of PDD for the number of patients was 0.9% (95% CI: 0.007 to 0.011). PDD was found to be associated with osseous changes, including changes in the morphology of the condyle, disc, and articular eminence; osseous abnormalities (erosion, osteophytes); and joint effusion. This meta-analysis showed a very low prevalence rate of PDD in TMD patients. The limited literature did not allow conclusions to be drawn about the PDD-related features."},"publication_date":"2018-08","publication_name":{"en":"Journal of Oral & Facial Pain and Headache","ja":"Journal of Oral & Facial Pain and Headache"},"volume":"Vol.32","number":"No.3","starting_page":"277","ending_page":"286","languages":["eng"],"referee":true,"identifiers":{"doi":["10.11607/ofph.1924"],"issn":["2333-0384"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:64, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111997","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/29091328","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85032792250&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=333997","label":"url"}],"paper_title":{"en":"Educational effects using a robot patient simulation system for development of clinical attitude","ja":"Educational effects using a robot patient simulation system for development of clinical attitude"},"authors":{"en":[{"name":"Abe Susumu"},{"name":"Noguchi Naoto"},{"name":"Matsuka Yoshizo"},{"name":"Shinohara Chihiro"},{"name":"Kimura Tomoko"},{"name":"Oka Kenji"},{"name":"Okura Kazuo"},{"name":"Rodis Omar"},{"name":"Kawano Fumiaki"}],"ja":[{"name":"安陪 晋"},{"name":"野口 直人"},{"name":"松香 芳三"},{"name":"篠原 千尋"},{"name":"木村 智子"},{"name":"岡 謙次"},{"name":"大倉 一夫"},{"name":"ロディス オマー"},{"name":"河野 文昭"}]},"description":{"en":"The aim of this study was to assess the effectiveness of improving the attitude of dental students towards the use of a full-body patient simulation system (SIMROID) compared to the traditional mannequin (CLINSIM) for dental clinical education. The participants were 10 male undergraduate dental students who had finished clinical training in the university hospital 1 year before this study started. They performed a crown preparation on an upper pre-molar tooth using SIMROID and CLINSIM as the practical clinical trials. The elapsed time for preparation was recorded. The taper of the abutment teeth was measured using a 3-dimensional shape-measuring device after this trial. In addition, a self-reported questionnaire was collected that included physical pain, treatment safety and maintaining a clean area for each simulator. Qualitative data analysis of a free format report about SIMROID was performed using text mining analysis. This trial was performed twice at 1-month intervals. The students considered physical pain, treatment safety and a clean area for SIMROID significantly better than that for CLINSIM (P < .01). The elapsed time of preparation in the second practical clinical trial was significantly lower than in the first for SIMROID and CLINSIM (P < .01). However, there were no significant differences between the abutment tapers for both systems. For the text mining analysis, most of the students wrote that SIMROID was similar to real patients. The use of SIMROID was proven to be effective in improving the attitude of students towards patients, thereby giving importance to considerations for actual patients during dental treatment.","ja":"The aim of this study was to assess the effectiveness of improving the attitude of dental students towards the use of a full-body patient simulation system (SIMROID) compared to the traditional mannequin (CLINSIM) for dental clinical education. The participants were 10 male undergraduate dental students who had finished clinical training in the university hospital 1 year before this study started. They performed a crown preparation on an upper pre-molar tooth using SIMROID and CLINSIM as the practical clinical trials. The elapsed time for preparation was recorded. The taper of the abutment teeth was measured using a 3-dimensional shape-measuring device after this trial. In addition, a self-reported questionnaire was collected that included physical pain, treatment safety and maintaining a clean area for each simulator. Qualitative data analysis of a free format report about SIMROID was performed using text mining analysis. This trial was performed twice at 1-month intervals. The students considered physical pain, treatment safety and a clean area for SIMROID significantly better than that for CLINSIM (P < .01). The elapsed time of preparation in the second practical clinical trial was significantly lower than in the first for SIMROID and CLINSIM (P < .01). However, there were no significant differences between the abutment tapers for both systems. For the text mining analysis, most of the students wrote that SIMROID was similar to real patients. The use of SIMROID was proven to be effective in improving the attitude of students towards patients, thereby giving importance to considerations for actual patients during dental treatment."},"publication_date":"2018-08","publication_name":{"en":"European Journal of Dental Education","ja":"European Journal of Dental Education"},"volume":"Vol.22","number":"No.3","starting_page":"e327","ending_page":"e336","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/eje.12298"],"issn":["1600-0579"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:65, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018871"},"force":{"see_also":[{"@id":"https://ci.nii.ac.jp/naid/130007402939/","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111933","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390845712973015552/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=349116","label":"url"}],"paper_title":{"en":"Time-course observation of patients with arthrosis of the temporomandibular joint on MRI","ja":"Time-course observation of patients with arthrosis of the temporomandibular joint on MRI"},"authors":{"en":[{"name":"Maeda Naoki"},{"name":"Hosoki Hidehiko"},{"name":"Yoshida Midori"},{"name":"Suito Hideki"},{"name":"Dashpuntsag Oyunbat"},{"name":"Matsumoto Fumihiro"},{"name":"Matsuka Yoshizo"},{"name":"Tanaka Eiji"},{"name":"Honda Eiichi"}],"ja":[{"name":"前田 直樹"},{"name":"細木 秀彦"},{"name":"吉田 みどり"},{"name":"水頭 英樹"},{"name":"Dashpuntsag Oyunbat"},{"name":"松本 文博"},{"name":"松香 芳三"},{"name":"田中 栄二"},{"name":"誉田 栄一"}]},"description":{"en":"Patients with arthrosis of the temporomandibular joint are examined by MRI, but fewer cases are followed over time by performing MRI several times. The objective of this study was to investigate the presence or absence and types of changes in the structure of the mandibular condyle and articular disc on MR images over time in patients examined by MRI for the diagnosis of arthritis of the temporomandibular joint in order to clarify the usefulness of performing MRI several times.
MR images for patients who underwent MRI several times based on the clinical diagnosis of arthrosis of the temporomandibular joint were analyzed.
Twenty-three patients were examined by MRI twice or more. The shortest and longest intervals between the first and final examinations were 75 and 2,588 days, respectively, and the mean was 735 days. Changes in the bone structure of the mandibular condyle were noted on the first MRI in approximately 63 % and new changes were noted on the final examination in approximately 24 %. In addition, the articular disc position in the closed or open mouth had changed on the later examinationin approximately 15 %.
Performing MRI several times along the clinical course was found to be useful to diagnose the disease stage, judge the treatment effects, and help predict the outcome in patients with arthrosis of the temporomandibular joint.","ja":"Patients with arthrosis of the temporomandibular joint are examined by MRI, but fewer cases are followed over time by performing MRI several times. The objective of this study was to investigate the presence or absence and types of changes in the structure of the mandibular condyle and articular disc on MR images over time in patients examined by MRI for the diagnosis of arthritis of the temporomandibular joint in order to clarify the usefulness of performing MRI several times.
MR images for patients who underwent MRI several times based on the clinical diagnosis of arthrosis of the temporomandibular joint were analyzed.
Twenty-three patients were examined by MRI twice or more. The shortest and longest intervals between the first and final examinations were 75 and 2,588 days, respectively, and the mean was 735 days. Changes in the bone structure of the mandibular condyle were noted on the first MRI in approximately 63 % and new changes were noted on the final examination in approximately 24 %. In addition, the articular disc position in the closed or open mouth had changed on the later examinationin approximately 15 %.
Performing MRI several times along the clinical course was found to be useful to diagnose the disease stage, judge the treatment effects, and help predict the outcome in patients with arthrosis of the temporomandibular joint."},"publication_date":"2018-07","publication_name":{"en":"Journal of Oral Health and Biosciences","ja":"Journal of Oral Health and Biosciences"},"volume":"Vol.31","number":"No.1","starting_page":"25","ending_page":"31","languages":["eng"],"referee":true,"identifiers":{"doi":["10.20738/johb.31.1_25"],"issn":["2188-7888"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:66, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018872"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/113362","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85049948297&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=354307","label":"url"}],"paper_title":{"en":"Effect of short-term Tumour Necrosis Factor-alpha (TNF-α) -stimulation on the growth and differentiation of MC3T3-E1 osteoblast-like cells","ja":"Effect of short-term Tumour Necrosis Factor-alpha (TNF-α) -stimulation on the growth and differentiation of MC3T3-E1 osteoblast-like cells"},"authors":{"en":[{"name":"Inoue Miho"},{"name":"Naritani Mio"},{"name":"Raju R"},{"name":"Miyagi Mayu"},{"name":"Ohshima Masamitsu"},{"name":"Masahisa Inoue"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"井上 美穂"},{"name":"成谷 美緒"},{"name":"RESMI RAJU"},{"name":"宮城 麻友"},{"name":"大島 正充"},{"name":"Masahisa Inoue"},{"name":"松香 芳三"}]},"publication_date":"2018-06-25","publication_name":{"en":"Journal of Hard Tissue Biology","ja":"Journal of Hard Tissue Biology"},"volume":"Vol.27","number":"No.3","starting_page":"213","ending_page":"218","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2485/jhtb.27.213"],"issn":["1880-828X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:67, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://ci.nii.ac.jp/naid/130007402937/","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111932","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282763020251776/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=342107","label":"url"}],"paper_title":{"en":"Radiographic investigation of the marginal bone loss on dental implants, a retrospective cohort study","ja":"Radiographic investigation of the marginal bone loss on dental implants, a retrospective cohort study"},"authors":{"en":[{"name":"Chimeddulam Gantumur"},{"name":"Nishigawa Keisuke"},{"name":"Naitou Yoshihito"},{"name":"Dalanon Junhel"},{"name":"Afroz S"},{"name":"Hayama Rika"},{"name":"Ohshima Masamitsu"},{"name":"Tomotake Yoritoki"},{"name":"Ichikawa Tetsuo"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Gantumur Chimeddulam"},{"name":"西川 啓介"},{"name":"内藤 禎人"},{"name":"Dalanon Junhel Casinillo"},{"name":"SHAISTA AFROZ"},{"name":"葉山 莉香"},{"name":"大島 正充"},{"name":"友竹 偉則"},{"name":"市川 哲雄"},{"name":"松香 芳三"}]},"description":{"en":"Background: During functional loading, the design of the dental implant may have an effect on the response of marginal bone.
Objectives: The purpose of this study was to report the prevalence of peri-implantitis, and to compare radiographic parameters around Brånemark and Replace Select dental implants and evaluate whether disparities in the morphologic features of these two indistinct implant systems, particularly their abutment-implant attachment, had an influence on the health of surrounding tissues and marginal bone loss (MBL).
Materials and Methods: Collection of data was done at the Department of Fixed Prosthodontics, the Department of Maxillo-Facial Prosthodontics, and Oral Implant Center of Tokushima University Hospital, in Tokushima, Japan; between March 2003 and followed until January 2017. Patients who have been treated with the Replace Select internal type implant and the Brånemark variety were selected as cohort. Marginal bone level measurements were evaluated via periapical and panoramic radiographs taken at regular follow-up visit. These dimensions were calculated, starting from the orientation mark at the implant abutment interface to the bottommost perceived contact area of marginal bone with the aforementioned implant system. The change in the level of bone was estimated by calculating the variation involving an initial reference value and the follow-up values.
Results: An average loss of bone at 0.65 ± 1.51 mm (range 0.36 to 7.89 mm) in the Replace Select group was observed, while in the Brånemark group 0.7 ± 1.32 mm (range 0.62 to 8.64 mm) was observed. Spearman rank correlation exhibited a statistically significant positive correlation between progress of bone loss around implant body and interval from implantation in the Brånemark group, whereas in the Replace Select group it was not significant. The Brånemark group exhibited significant (P = 0.0269) negative correlation of MBL and its diameters, whereas the Replace Select group did not exhibit such correlation.
Conclusion: Within the limits of this study, it can be concluded that deviations in the morphologic attributes of these two diverse implant systems had an influence on the health of surrounding tissues and MBL. The Brånemark implants showed a significant increase in MBL (> 1.8mm) as the time of placement elapses. This marked MBL was greater in females than males, in posterior than in anterior, and in the narrow platform implants than the regular platform implants or the wide platform implants. On the other hand, results suggested that this bone loss was greater in the mandible than the maxilla, in single-unit implant crowns than multiple implant restorations in the Replace Select group.","ja":"Background: During functional loading, the design of the dental implant may have an effect on the response of marginal bone.Objectives: The purpose of this study was to report the prevalence of peri-implantitis, and to compare radiographic parameters around Brånemark and Replace Select dental implants and evaluate whether disparities in the morphologic features of these two indistinct implant systems, particularly their abutment-implant attachment, had an influence on the health of surrounding tissues and marginal bone loss (MBL).Materials and Methods: Collection of data was done at the Department of Fixed Prosthodontics, the Department of Maxillo-Facial Prosthodontics, and Oral Implant Center of Tokushima University Hospital, in Tokushima, Japan; between March 2003 and followed until January 2017. Patients who have been treated with the Replace Select internal type implant and the Brånemark variety were selected as cohort. Marginal bone level measurements were evaluated via periapical and panoramic radiographs taken at regular follow-up visit. These dimensions were calculated, starting from the orientation mark at the implant abutment interface to the bottommost perceived contact area of marginal bone with the aforementioned implant system. The change in the level of bone was estimated by calculating the variation involving an initial reference value and the follow-up values.Results: An average loss of bone at 0.65 ± 1.51 mm (range 0.36 to 7.89 mm) in the Replace Select group was observed, while in the Brånemark group 0.7 ± 1.32 mm (range 0.62 to 8.64 mm) was observed. Spearman rank correlation exhibited a statistically significant positive correlation between progress of bone loss around implant body and interval from implantation in the Brånemark group, whereas in the Replace Select group it was not significant. The Brånemark group exhibited significant (P = 0.0269) negative correlation of MBL and its diameters, whereas the Replace Select group did not exhibit such correlation.Conclusion: Within the limits of this study, it can be concluded that deviations in the morphologic attributes of these two diverse implant systems had an influence on the health of surrounding tissues and MBL. The Brånemark implants showed a significant increase in MBL (> 1.8mm) as the time of placement elapses. This marked MBL was greater in females than males, in posterior than in anterior, and in the narrow platform implants than the regular platform implants or the wide platform implants. On the other hand, results suggested that this bone loss was greater in the mandible than the maxilla, in single-unit implant crowns than multiple implant restorations in the Replace Select group."},"publication_date":"2018-06","publication_name":{"en":"Journal of Oral Health and Biosciences","ja":"Journal of Oral Health and Biosciences"},"volume":"Vol.31","number":"No.1","starting_page":"13","ending_page":"24","languages":["eng"],"referee":true,"identifiers":{"doi":["10.20738/johb.31.1_13"],"issn":["2188-7888"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:68, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=339729","label":"url"}],"paper_title":{"en":"An investigation of the Filipino dental students' personality types","ja":"An investigation of the Filipino dental students' personality types"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"松香 芳三"}]},"publication_date":"2018-05","publication_name":{"en":"Philippine Journal of Health Research and Development","ja":"Philippine Journal of Health Research and Development"},"volume":"Vol.22","number":"No.2","starting_page":"12","ending_page":"17","languages":["eng"],"referee":true,"published_paper_type":"scientific_journal"},"priority":"input_data"} line:69, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39018873"},"force":{"see_also":[{"@id":"https://cir.nii.ac.jp/crid/1390001205299655552/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=337736","label":"url"}],"paper_title":{"en":"咬合違和感の診断と対処法","ja":"咬合違和感の診断と対処法"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"玉置 勝司"},{"name":"Hayama Rika"},{"name":"Abe Susumu"},{"name":"宮城 麻友"},{"name":"Horikawa Eriko"},{"name":"Naritani Mio"},{"name":"野田 千織"},{"name":"Ohshima Masamitsu"},{"name":"Kawano Fumiaki"}],"ja":[{"name":"松香 芳三"},{"name":"玉置 勝司"},{"name":"葉山 莉香"},{"name":"安陪 晋"},{"name":"宮城 麻友"},{"name":"堀川 恵理子"},{"name":"成谷 美緒"},{"name":"野田 千織"},{"name":"大島 正充"},{"name":"河野 文昭"}]},"publication_date":"2018-04-10","publication_name":{"en":"Annals of Japan Prosthodontic Society","ja":"日本補綴歯科学会誌"},"volume":"Vol.10","number":"No.2","starting_page":"129","ending_page":"133","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.2186/ajps.10.129"],"issn":["1883-6860"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:70, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=336878","label":"url"}],"paper_title":{"en":"Organizational dilemma: Dental faculty acquisition in the Philippines","ja":"Organizational dilemma: Dental faculty acquisition in the Philippines"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Gimena AJ"},{"name":"Arreza AC"},{"name":"Jalbuna JA"},{"name":"Salinas L"},{"name":"Tumamac M"},{"name":"Belarmino MP"},{"name":"Esguerra R"},{"name":"Docor R"},{"name":"Goto Nami"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"Gimena AJ"},{"name":"Arreza AC"},{"name":"Jalbuna JA"},{"name":"Salinas L"},{"name":"Tumamac M"},{"name":"Belarmino MP"},{"name":"Esguerra R"},{"name":"Docor R"},{"name":"Goto Nami"},{"name":"松香 芳三"}]},"publication_date":"2018-03","publication_name":{"en":"IOSR Journal of Business and Management","ja":"IOSR Journal of Business and Management"},"volume":"Vol.20","number":"No.3","starting_page":"65","ending_page":"71","languages":["eng"],"referee":true,"identifiers":{"issn":["2278-487X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:71, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=336395","label":"url"}],"paper_title":{"en":"Technology acceptance model in the use of a patient management software in a dental school in the Philippines","ja":"Technology acceptance model in the use of a patient management software in a dental school in the Philippines"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Gabinete JG"},{"name":"NainaJavier H"},{"name":"Galang KJ"},{"name":"Perales A"},{"name":"Sorela C"},{"name":"Belarmino MP"},{"name":"Esguerra R"},{"name":"Docor R"},{"name":"Afroz S"},{"name":"Iwasa Takuma"},{"name":"Rodis Omar"},{"name":"Suzuki Yoshitaka"},{"name":"Okura Kazuo"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"Gabinete JG"},{"name":"NainaJavier H"},{"name":"Galang KJ"},{"name":"Perales A"},{"name":"Sorela C"},{"name":"Belarmino MP"},{"name":"Esguerra R"},{"name":"Docor R"},{"name":"Afroz S"},{"name":"岩浅 匠真"},{"name":"ロディス オマー"},{"name":"鈴木 善貴"},{"name":"大倉 一夫"},{"name":"松香 芳三"}]},"publication_date":"2018-02","publication_name":{"en":"IOSR Journal of Dental and Medical Sciences","ja":"IOSR Journal of Dental and Medical Sciences"},"volume":"Vol.17","number":"No.2","starting_page":"65","ending_page":"69","languages":["eng"],"referee":true,"identifiers":{"doi":["10.9790/0853-1702086569"],"issn":["2279-0853"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:72, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=336126","label":"url"}],"paper_title":{"en":"A Philippine rural schools organizational climate, teachers performance, and management competencies","ja":"A Philippine rural schools organizational climate, teachers performance, and management competencies"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Diano LM"},{"name":"Belarmino MP"},{"name":"Hayama Rika"},{"name":"Miyagi Mayu"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"Diano LM"},{"name":"Belarmino MP"},{"name":"葉山 莉香"},{"name":"宮城 麻友"},{"name":"松香 芳三"}]},"publication_date":"2018-01","publication_name":{"en":"International Journal of Research -GRANTHAALAYAH","ja":"International Journal of Research -GRANTHAALAYAH"},"volume":"Vol.6","number":"No.1","starting_page":"248","ending_page":"265","languages":["eng"],"referee":true,"identifiers":{"doi":["10.5281/zenodo.1164303"],"issn":["2350-0530"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:73, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=335866","label":"url"}],"paper_title":{"en":"Filipino teachers sense of efficacy inclusion classes","ja":"Filipino teachers sense of efficacy inclusion classes"},"authors":{"en":[{"name":"Dalanon Junhel"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Dalanon Junhel Casinillo"},{"name":"松香 芳三"}]},"publication_date":"2017-12","publication_name":{"en":"Asia Pacific Journal of Research","ja":"Asia Pacific Journal of Research"},"volume":"Vol.1","number":"No.58","starting_page":"339","ending_page":"343","languages":["eng"],"referee":true,"identifiers":{"doi":["10.5281/zenodo.1161784"],"issn":["2320-5504"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:74, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/112932","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/29196333","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85038129509&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=335456","label":"url"}],"paper_title":{"en":"Validity of peer evaluation for team-based learning in a dental school in Japan","ja":"Validity of peer evaluation for team-based learning in a dental school in Japan"},"authors":{"en":[{"name":"Nishigawa Keisuke"},{"name":"Hayama Rika"},{"name":"Omoto Ktsushi"},{"name":"Okura Kazuo"},{"name":"Tajima Toyoko"},{"name":"Suzuki Yoshitaka"},{"name":"Hosoki Maki"},{"name":"Miyagi Mayu"},{"name":"Inoue Miho"},{"name":"Rodis Omar"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"西川 啓介"},{"name":"葉山 莉香"},{"name":"Omoto Ktsushi"},{"name":"大倉 一夫"},{"name":"田島 登誉子"},{"name":"鈴木 善貴"},{"name":"細木 眞紀"},{"name":"宮城 麻友"},{"name":"井上 美穂"},{"name":"ロディス オマー"},{"name":"松香 芳三"}]},"description":{"en":"The aim of this study was to determine the validity of peer evaluation for team-based learning (TBL) classes in dental education in comparison with the term-end examination records and TBL class scores. Examination and TBL class records of 256 third- and fourth-year dental students in six fixed prosthodontics courses from 2013 to 2015 in one dental school in Japan were investigated. Results of the term-end examination during those courses, individual readiness assurance test (IRAT), group readiness assurance test (GRAT), group assignment projects (GAP), and peer evaluation of group members in TBL classes were collected. Significant positive correlations were found between all combinations of peer evaluation, IRAT, and term-end examination. Individual scores also showed a positive correlation with group score (total of GRAT and GAP). From the investigation of the correlations in the six courses, significant positive correlations between peer evaluation and individual score were found in four of the six courses. In this study, peer evaluation seemed to be a valid index for learning performance in TBL classes. To verify the effectiveness of peer evaluation, all students have to realize the significance of scoring the team member's performance. Clear criteria and detailed instruction for appropriate evaluation are also required.","ja":"The aim of this study was to determine the validity of peer evaluation for team-based learning (TBL) classes in dental education in comparison with the term-end examination records and TBL class scores. Examination and TBL class records of 256 third- and fourth-year dental students in six fixed prosthodontics courses from 2013 to 2015 in one dental school in Japan were investigated. Results of the term-end examination during those courses, individual readiness assurance test (IRAT), group readiness assurance test (GRAT), group assignment projects (GAP), and peer evaluation of group members in TBL classes were collected. Significant positive correlations were found between all combinations of peer evaluation, IRAT, and term-end examination. Individual scores also showed a positive correlation with group score (total of GRAT and GAP). From the investigation of the correlations in the six courses, significant positive correlations between peer evaluation and individual score were found in four of the six courses. In this study, peer evaluation seemed to be a valid index for learning performance in TBL classes. To verify the effectiveness of peer evaluation, all students have to realize the significance of scoring the team member's performance. Clear criteria and detailed instruction for appropriate evaluation are also required."},"publication_date":"2017-12","publication_name":{"en":"Journal of Dental Education","ja":"Journal of Dental Education"},"volume":"Vol.81","number":"No.12","starting_page":"1451","ending_page":"1456","languages":["eng"],"referee":true,"identifiers":{"doi":["10.21815/JDE.017.106"],"issn":["1930-7837"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:75, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://ci.nii.ac.jp/naid/40021481734/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520290884130282880/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=321869","label":"url"}],"paper_title":{"en":"Frequency of congenitally missing permanent teeth at a primary dental care clinic in Tokushima, Japan","ja":"Frequency of congenitally missing permanent teeth at a primary dental care clinic in Tokushima, Japan"},"authors":{"en":[{"name":"Inoue Miho"},{"name":"Hiroo KAWAHARA"},{"name":"Okura Kazuo"},{"name":"Miyagi Mayu"},{"name":"Mio NARITANI"},{"name":"Iwasa Takuma"},{"name":"Katsuhiro OMOTO"},{"name":"Rodis Omar"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"井上 美穂"},{"name":"川原 博雄"},{"name":"大倉 一夫"},{"name":"宮城 麻友"},{"name":"Mio NARITANI"},{"name":"岩浅 匠真"},{"name":"Katsuhiro OMOTO"},{"name":"ロディス オマー"},{"name":"松香 芳三"}]},"publication_date":"2017-12","publication_name":{"en":"The Journal of Japan Association of Oral Rehabilitation","ja":"The Journal of Japan Association of Oral Rehabilitation"},"volume":"Vol.30","number":"No.1","starting_page":"67","ending_page":"70","languages":["eng"],"referee":true,"identifiers":{"issn":["2186-2052"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:76, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=335175","label":"url"}],"paper_title":{"en":"Effects of Custom-made Mouthguard Use on Physical Performance and Concentration","ja":"Effects of Custom-made Mouthguard Use on Physical Performance and Concentration"},"authors":{"en":[{"name":"Suzuki Yoshitaka"},{"name":"Okura Kazuo"},{"name":"Omoto Katsuhiro"},{"name":"Takikawa Saya"},{"name":"Nishigawa Keisuke"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"鈴木 善貴"},{"name":"大倉 一夫"},{"name":"大本 勝弘"},{"name":"多喜川 紗耶"},{"name":"西川 啓介"},{"name":"松香 芳三"}]},"publication_date":"2017-11","publication_name":{"en":"The International Journal of Sports Dentistry","ja":"The International Journal of Sports Dentistry"},"volume":"Vol.10","number":"No.1","starting_page":"22","ending_page":"31","languages":["eng"],"referee":true,"published_paper_type":"scientific_journal"},"priority":"input_data"} line:77, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111973","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/27561445","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84997684106&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=313826","label":"url"}],"paper_title":{"en":"Complications causing patients to discontinue using oral appliances for treatment of obstructive sleep apnea","ja":"Complications causing patients to discontinue using oral appliances for treatment of obstructive sleep apnea"},"authors":{"en":[{"name":"Nishigawa Keisuke"},{"name":"Hayama Rika"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"西川 啓介"},{"name":"葉山 莉香"},{"name":"松香 芳三"}]},"description":{"en":"Oral appliances (OAs) are commonly used as a noninvasive treatment for obstructive sleep apnea syndrome (OSAS). These devices are worn during sleep and create mandibular anterior traction to enlarge the upper airway. Continuous use of the device is essential for the success of OA therapy, but some patients stop using the OA for various reasons. The purpose of this research was to investigate complications in OA therapy that might prevent continuous use of these devices. The progress of 90 OSAS patients who visited Tokushima University Hospital and underwent OA therapy was investigated with a mailed questionnaire. All patients had been receiving OA therapy for more than 12 months. Forty patients responded to the questionnaire and of these, 22 were not wearing their OA during sleep. The average period before stopping OA therapy was 9.6 months. Answers from 38 patients who were treated with two-piece Herbst(®)-type oral appliances were analyzed. The main reasons for stopping OA therapy were: (1) it was bothersome to use; and (2) it did not effectively prevent sleep apnea. Comparison of OA complications between current OA users and nonusers revealed significant differences for the items \"difficulty sleeping\" and \"stifling feeling\". OA users recorded better scores for sleep quality than nonusers. The results of this study indicate that patients discontinued OA therapy because the appliance was \"bothersome to use\" and because it had \"little or no effect\" rather than because they experienced the typical complications of OA therapy.","ja":"Oral appliances (OAs) are commonly used as a noninvasive treatment for obstructive sleep apnea syndrome (OSAS). These devices are worn during sleep and create mandibular anterior traction to enlarge the upper airway. Continuous use of the device is essential for the success of OA therapy, but some patients stop using the OA for various reasons. The purpose of this research was to investigate complications in OA therapy that might prevent continuous use of these devices. The progress of 90 OSAS patients who visited Tokushima University Hospital and underwent OA therapy was investigated with a mailed questionnaire. All patients had been receiving OA therapy for more than 12 months. Forty patients responded to the questionnaire and of these, 22 were not wearing their OA during sleep. The average period before stopping OA therapy was 9.6 months. Answers from 38 patients who were treated with two-piece Herbst(®)-type oral appliances were analyzed. The main reasons for stopping OA therapy were: (1) it was bothersome to use; and (2) it did not effectively prevent sleep apnea. Comparison of OA complications between current OA users and nonusers revealed significant differences for the items \"difficulty sleeping\" and \"stifling feeling\". OA users recorded better scores for sleep quality than nonusers. The results of this study indicate that patients discontinued OA therapy because the appliance was \"bothersome to use\" and because it had \"little or no effect\" rather than because they experienced the typical complications of OA therapy."},"publication_date":"2017-04","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.61","number":"No.2","starting_page":"133","ending_page":"138","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2016.08.001"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:78, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111995","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=310781","label":"url"}],"paper_title":{"en":"Comparison between flipped classroom and team-based learning in fixed prosthodontic education Journal of Prosthodontic Research","ja":"Comparison between flipped classroom and team-based learning in fixed prosthodontic education Journal of Prosthodontic Research"},"authors":{"en":[{"name":"Nishigawa Keisuke"},{"name":"Omoto K"},{"name":"Hayama Rika"},{"name":"Chimeddulam Gantumur"},{"name":"Okura Kazuo"},{"name":"Tajima Toyoko"},{"name":"Suzuki Yoshitaka"},{"name":"Hosoki Maki"},{"name":"Shigemoto Shuji"},{"name":"Miyagi Mayu"},{"name":"Rodis OMM"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"西川 啓介"},{"name":"大本 勝弘"},{"name":"葉山 莉香"},{"name":"Gantumur Chimeddulam"},{"name":"大倉 一夫"},{"name":"田島 登誉子"},{"name":"鈴木 善貴"},{"name":"細木 眞紀"},{"name":"重本 修伺"},{"name":"宮城 麻友"},{"name":"Rodis OMM"},{"name":"松香 芳三"}]},"publication_date":"2017-04","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.61","number":"No.2","starting_page":"217","ending_page":"222","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2016.04.003"],"issn":["1883-1958"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:79, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111971","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/27514568","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84994339218&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=314246","label":"url"}],"paper_title":{"en":"Reliability and validity of the patient disability-oriented diagnostic nomenclature system for prosthetic dentistry","ja":"Reliability and validity of the patient disability-oriented diagnostic nomenclature system for prosthetic dentistry"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Hagiwara Yoshiyuki"},{"name":"Tamaki Katsushi"},{"name":"Takeuchi Hisahiro"},{"name":"Fujisawa Masanori"},{"name":"Ono Takahiro"},{"name":"Tsukiyama Yoshihiro"},{"name":"Nagao Kan"},{"name":"Tsuga Kazuhiro"},{"name":"Aita Hideki"},{"name":"Kondo Hisatomo"},{"name":"Fueki Kenji"},{"name":"Tsukasaki Hiroaki"},{"name":"Nishigawa Keisuke"},{"name":"Ozawa Shogo"},{"name":"Kuwatsuru Rika"},{"name":"Minakuchi Hajime"},{"name":"Iinuma Toshimitsu"},{"name":"Matsuura Takashi"},{"name":"Ishibashi Kanji"},{"name":"Fujii Shigehisa"},{"name":"Hirai Toshihiro"},{"name":"Sasaki Keiichi"},{"name":"Yatani Hirofumi"},{"name":"Igarashi Yoshimasa"},{"name":"Sato Yuji"},{"name":"Ichikawa Tetsuo"},{"name":"Yamamori Tetsuo"},{"name":"Kuboki Takuo"},{"name":"Baba Kazuyoshi"},{"name":"Koyano Kiyoshi"},{"name":"Sato Hironobu"},{"name":"Hideo Matsumura"}],"ja":[{"name":"松香 芳三"},{"name":"Hagiwara Yoshiyuki"},{"name":"Tamaki Katsushi"},{"name":"Takeuchi Hisahiro"},{"name":"Fujisawa Masanori"},{"name":"Ono Takahiro"},{"name":"Tsukiyama Yoshihiro"},{"name":"永尾 寛"},{"name":"Tsuga Kazuhiro"},{"name":"Aita Hideki"},{"name":"Kondo Hisatomo"},{"name":"Fueki Kenji"},{"name":"Tsukasaki Hiroaki"},{"name":"西川 啓介"},{"name":"Ozawa Shogo"},{"name":"Kuwatsuru Rika"},{"name":"Minakuchi Hajime"},{"name":"Iinuma Toshimitsu"},{"name":"Matsuura Takashi"},{"name":"Ishibashi Kanji"},{"name":"Fujii Shigehisa"},{"name":"Hirai Toshihiro"},{"name":"Sasaki Keiichi"},{"name":"Yatani Hirofumi"},{"name":"Igarashi Yoshimasa"},{"name":"Sato Yuji"},{"name":"市川 哲雄"},{"name":"Yamamori Tetsuo"},{"name":"Kuboki Takuo"},{"name":"Baba Kazuyoshi"},{"name":"Koyano Kiyoshi"},{"name":"Sato Hironobu"},{"name":"Hideo Matsumura"}]},"description":{"en":"The Japan Prosthodontic Society (JPS) has proposed a new diagnostic nomenclature system (DNS), based on pathogenesis and etiology, to facilitate and improve prosthodontic treatment. This system specifies patient disability and the causative factor (i.e. \"B (disability) caused by A (causative factor)\"). The purpose of this study was to examine the reliability and validity of this DNS. The JPS Clinical Guideline Committee assessed mock patient charts and formulated disease names using the new DNS. Fifty validators, comprising prosthodontic specialists and dental residents, made diagnoses using the same patient charts. Reliability was evaluated as the consistency of the disease names among the validators, and validity was evaluated using the concordance rate of the disease names with the reference disease names. Krippendorff's α was 0.378 among all validators, 0.370 among prosthodontic specialists, and 0.401 among dental hospital residents. Krippendorff's α for 10 validators (3 specialists and 7 residents) with higher concordance rates was 0.524. Two validators (1 specialist and 1 resident) with the highest concordance rates had a Krippendorff's α of 0.648. Common disease names had higher concordance rates, while uncommon disease names showed lower concordance rates. These rates did not show correlation with clinical experience of the validator or time taken to devise the disease name. High reliability was not found among all validators; however, validators with higher concordance rates showed better reliability. Furthermore, common disease names had higher concordance rates. These findings indicate that the new DNS for prosthodontic dentistry exhibits clinically acceptable reliability and validity.","ja":"The Japan Prosthodontic Society (JPS) has proposed a new diagnostic nomenclature system (DNS), based on pathogenesis and etiology, to facilitate and improve prosthodontic treatment. This system specifies patient disability and the causative factor (i.e. \"B (disability) caused by A (causative factor)\"). The purpose of this study was to examine the reliability and validity of this DNS. The JPS Clinical Guideline Committee assessed mock patient charts and formulated disease names using the new DNS. Fifty validators, comprising prosthodontic specialists and dental residents, made diagnoses using the same patient charts. Reliability was evaluated as the consistency of the disease names among the validators, and validity was evaluated using the concordance rate of the disease names with the reference disease names. Krippendorff's α was 0.378 among all validators, 0.370 among prosthodontic specialists, and 0.401 among dental hospital residents. Krippendorff's α for 10 validators (3 specialists and 7 residents) with higher concordance rates was 0.524. Two validators (1 specialist and 1 resident) with the highest concordance rates had a Krippendorff's α of 0.648. Common disease names had higher concordance rates, while uncommon disease names showed lower concordance rates. These rates did not show correlation with clinical experience of the validator or time taken to devise the disease name. High reliability was not found among all validators; however, validators with higher concordance rates showed better reliability. Furthermore, common disease names had higher concordance rates. These findings indicate that the new DNS for prosthodontic dentistry exhibits clinically acceptable reliability and validity."},"publication_date":"2017-01","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.61","number":"No.1","starting_page":"20","ending_page":"33","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2016.06.005"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:80, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/112028","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/27354030","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84977478853&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=313838","label":"url"}],"paper_title":{"en":"Mandibular movement during sleep bruxism associated with current tooth attrition","ja":"Mandibular movement during sleep bruxism associated with current tooth attrition"},"authors":{"en":[{"name":"Okura Kazuo"},{"name":"Shigemoto Shuji"},{"name":"Suzuki Yoshitaka"},{"name":"Noguchi Naoto"},{"name":"Omoto Katsuhiro"},{"name":"Abe Susumu"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"大倉 一夫"},{"name":"重本 修伺"},{"name":"鈴木 善貴"},{"name":"野口 直人"},{"name":"大本 勝弘"},{"name":"安陪 晋"},{"name":"松香 芳三"}]},"description":{"en":"Observation of attrition patterns suggests that mandibular movement in sleep bruxism (SB) may be associated with current tooth attrition. The aim of this study was to confirm this phenomenon by investigating mandibular movement and masseter muscle activity. The subject was a healthy 21-year-old Japanese male. We recorded biological signals including mandibular movement and masseter electromyograms (EMGs) with a polysomnograph. Based on the EMG using Okura's criteria, SB events were classified into clenching, grinding and mixed types according to mandibular movement criteria. The close-open mandibular movement cycles (CO-cycles) during grinding and mixed type events were selected based on mandibular movement trajectories. Fifty-eight CO-cycles were selected in seven grinding and three mixed types. We found that SB mandibular movements associated with current tooth attrition. Excessive lateral movements (ELM) beyond the canine edge-to-edge position were observed in the closing (10.3%) and opening (13.8%) phases of the CO-cycle. Total masseter muscle activity was significantly higher during voluntary grinding (VGR) than during CO-cycle including ELM (working side: P=0.036, balancing side: P=0.025). However, in the middle and late parts of the opening phase, working side masseter muscle activity was significantly higher during CO-cycle including ELM than during VGR (P=0.012). In the early part of the closing phase, balancing side masseter muscle activity was significantly higher during CO-cycle including ELM than during VGR (P=0.017). These findings suggest that excessive forceful grinding during ongoing SB events may have caused canine attrition in this patient.","ja":"Observation of attrition patterns suggests that mandibular movement in sleep bruxism (SB) may be associated with current tooth attrition. The aim of this study was to confirm this phenomenon by investigating mandibular movement and masseter muscle activity. The subject was a healthy 21-year-old Japanese male. We recorded biological signals including mandibular movement and masseter electromyograms (EMGs) with a polysomnograph. Based on the EMG using Okura's criteria, SB events were classified into clenching, grinding and mixed types according to mandibular movement criteria. The close-open mandibular movement cycles (CO-cycles) during grinding and mixed type events were selected based on mandibular movement trajectories. Fifty-eight CO-cycles were selected in seven grinding and three mixed types. We found that SB mandibular movements associated with current tooth attrition. Excessive lateral movements (ELM) beyond the canine edge-to-edge position were observed in the closing (10.3%) and opening (13.8%) phases of the CO-cycle. Total masseter muscle activity was significantly higher during voluntary grinding (VGR) than during CO-cycle including ELM (working side: P=0.036, balancing side: P=0.025). However, in the middle and late parts of the opening phase, working side masseter muscle activity was significantly higher during CO-cycle including ELM than during VGR (P=0.012). In the early part of the closing phase, balancing side masseter muscle activity was significantly higher during CO-cycle including ELM than during VGR (P=0.017). These findings suggest that excessive forceful grinding during ongoing SB events may have caused canine attrition in this patient."},"publication_date":"2017-01","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.61","number":"No.1","starting_page":"87","ending_page":"95","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2016.06.003"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:81, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=323954","label":"url"}],"paper_title":{"en":"Investigation of Effect on Physical Performance and Concentration by Custom-made Mouthguard Use","ja":"Investigation of Effect on Physical Performance and Concentration by Custom-made Mouthguard Use"},"authors":{"en":[{"name":"Suzuki Yoshitaka"},{"name":"Okura Kazuo"},{"name":"Omoto Katsuhiko"},{"name":"Takikawa Saya"},{"name":"Nishigawa Keisuke"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"鈴木 善貴"},{"name":"大倉 一夫"},{"name":"Omoto Katsuhiko"},{"name":"Takikawa Saya"},{"name":"西川 啓介"},{"name":"松香 芳三"}]},"publication_date":"2017","publication_name":{"en":"International Journal of Sports Dentistry","ja":"International Journal of Sports Dentistry"},"volume":"Vol.10","number":"No.1","starting_page":"1","ending_page":"10","languages":["eng"],"referee":true,"published_paper_type":"scientific_journal"},"priority":"input_data"} line:82, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://cir.nii.ac.jp/crid/1390001205300490880/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=323296","label":"url"}],"paper_title":{"en":"Glossopharyngeal Neuralgia Caused by Diabetes Mellitus","ja":"糖尿病神経障害と診断された舌咽神経痛の一症例"},"authors":{"en":[{"name":"Matsumoto Fumihiro"},{"name":"Momota Yukihiro"},{"name":"Takano Hideyuki"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"松本 文博"},{"name":"桃田 幸弘"},{"name":"高野 栄之"},{"name":"松香 芳三"}]},"publication_date":"2016-12-25","publication_name":{"en":"Japanese Journal of Orofacial Pain","ja":"日本口腔顔面痛学会雑誌"},"volume":"Vol.9","number":"No.1","starting_page":"81","ending_page":"85","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11264/jjop.9.81"],"issn":["1882-9333"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:83, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://repo.lib.tokushima-u.ac.jp/113901","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/113901","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1050564288893446528/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=306208","label":"url"}],"paper_title":{"en":"Preliminary study of neural excitation with positron emission tomography after tooth mechanical stimulation","ja":"Preliminary study of neural excitation with positron emission tomography after tooth mechanical stimulation"},"authors":{"en":[{"name":"Omoto Katsuhiro"},{"name":"Iwasa Takuma"},{"name":"Afroz Shaista"},{"name":"Miyagi Mayu"},{"name":"Okura Kazuo"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Omoto Katsuhiro"},{"name":"Iwasa Takuma"},{"name":"Afroz Shaista"},{"name":"宮城 麻友"},{"name":"大倉 一夫"},{"name":"松香 芳三"}]},"description":{"en":"Dentists often cannot objectively find abnormalities in patients who complain of discomfort or abnormal sensation in their dental occlusion. We hypothesized that abnormal neural transmission from the tooth is related to this occlusal discomfort sensation. Chronic tooth contact habits may induce neural excitation from the tooth to the central nervous system, and may aggravate the sensation of discomfort in the central nervous system. However, the details of neural transmission from the tooth to the central nervous system are still unclear. In this study, we stimulated a rat premolar mechanically and observed activated bran sites using positron emission tomography (PET) and 18F-2-fluoro-2-deoxy-D-glucose (FDG). We anesthetized 5-7-week-old male rats using isoflurane inhalation anesthesia and stimulated the upper right premolar mechanically with an electric von Frey system (Model 1601C, IITC Instruments) by measuring mechanical pressure. Before the tooth mechanical stimulation, we injected FDG through the rat's caudal vein and then used a stimulation intensity of 100, 200 or 300 g. We recorded FDG accumulation with PET. The PET brain images were separated into four parts (right higher, left higher, right lower and left lower) for analysis and the peak value of striatal uptake (SUV) in each part was analyzed. The PET images showed that the accumulated FDG in the right lower part of the brain was higher with 300 g tooth stimulation than with 100 or 200 g. The data showed that the tooth stimulation site in the lower part of the brain was activated with tooth stimulation by comparing it with the other parts. We also measured SUV in the right and left sensory areas, motor area, hippocampus, trigeminal ganglia (TG) and spinal cord. The TG and sensory area showed more FDG accumulation compared with mouth opening.","ja":"Dentists often cannot objectively find abnormalities in patients who complain of discomfort or abnormal sensation in their dental occlusion. We hypothesized that abnormal neural transmission from the tooth is related to this occlusal discomfort sensation. Chronic tooth contact habits may induce neural excitation from the tooth to the central nervous system, and may aggravate the sensation of discomfort in the central nervous system. However, the details of neural transmission from the tooth to the central nervous system are still unclear. In this study, we stimulated a rat premolar mechanically and observed activated bran sites using positron emission tomography (PET) and 18F-2-fluoro-2-deoxy-D-glucose (FDG). We anesthetized 5-7-week-old male rats using isoflurane inhalation anesthesia and stimulated the upper right premolar mechanically with an electric von Frey system (Model 1601C, IITC Instruments) by measuring mechanical pressure. Before the tooth mechanical stimulation, we injected FDG through the rat's caudal vein and then used a stimulation intensity of 100, 200 or 300 g. We recorded FDG accumulation with PET. The PET brain images were separated into four parts (right higher, left higher, right lower and left lower) for analysis and the peak value of striatal uptake (SUV) in each part was analyzed. The PET images showed that the accumulated FDG in the right lower part of the brain was higher with 300 g tooth stimulation than with 100 or 200 g. The data showed that the tooth stimulation site in the lower part of the brain was activated with tooth stimulation by comparing it with the other parts. We also measured SUV in the right and left sensory areas, motor area, hippocampus, trigeminal ganglia (TG) and spinal cord. The TG and sensory area showed more FDG accumulation compared with mouth opening."},"publication_date":"2016-12","publication_name":{"en":"The Journal of Japan Association of Oral Rehabilitation","ja":"The Journal of Japan Association of Oral Rehabilitation"},"volume":"Vol.29","number":"No.1","starting_page":"28","ending_page":"34","languages":["eng"],"referee":true,"identifiers":{"issn":["2186-2052"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:84, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/40021090289/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520290883209041664/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=306041","label":"url"}],"paper_title":{"en":"Relationship between the mandibular movements and deformation of the coronoid process and the condyle","ja":"Relationship between the mandibular movements and deformation of the coronoid process and the condyle"},"authors":{"en":[{"name":"Hirai Shinya"},{"name":"Shigemoto Shuji"},{"name":"Shigeta Yuko"},{"name":"Kamei Shu"},{"name":"Ogawa Takumi"},{"name":"Ando Eriko"},{"name":"Hirabayashi Rio"},{"name":"Ikawa Tomoko"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Hirai Shinya"},{"name":"重本 修伺"},{"name":"Shigeta Yuko"},{"name":"Kamei Shu"},{"name":"Ogawa Takumi"},{"name":"Ando Eriko"},{"name":"Hirabayashi Rio"},{"name":"Ikawa Tomoko"},{"name":"松香 芳三"}]},"publication_date":"2016-12","publication_name":{"en":"The Journal of Japan Association of Oral Rehabilitation","ja":"The Journal of Japan Association of Oral Rehabilitation"},"volume":"Vol.29","number":"No.1","starting_page":"35","ending_page":"40","languages":["eng"],"referee":true,"identifiers":{"issn":["2186-2052"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:85, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797044"},"force":{"see_also":[{"@id":"https://ci.nii.ac.jp/naid/40021090255/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520572359226098048/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=306040","label":"url"}],"paper_title":{"en":"The effect of splints on sleep bruxism : a preliminary study","ja":"スプリントによる睡眠時ブラキシズムに対する治療効果 : 予備的検討"},"authors":{"en":[{"name":"Okura Kazuo"},{"name":"Suzuki Yoshitaka"},{"name":"Shigemoto Shuji"},{"name":"大本 勝弘"},{"name":"葉山 莉香"},{"name":"岩浅 匠真"},{"name":"福本 美緒"},{"name":"井上 美穂"},{"name":"Miyagi Mayu"},{"name":"Abe Susumu"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"大倉 一夫"},{"name":"鈴木 善貴"},{"name":"重本 修伺"},{"name":"大本 勝弘"},{"name":"葉山 莉香"},{"name":"岩浅 匠真"},{"name":"福本 美緒"},{"name":"井上 美穂"},{"name":"宮城 麻友"},{"name":"安陪 晋"},{"name":"松香 芳三"}]},"publication_date":"2016-12","publication_name":{"en":"The Journal of Japan Association of Oral Rehabilitation","ja":"日本口腔リハビリテーション学会雑誌"},"volume":"Vol.29","number":"No.1","starting_page":"21","ending_page":"27","languages":["jpn"],"referee":true,"identifiers":{"issn":["2186-2052"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:86, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/114150","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390002184854862720/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=321089","label":"url"}],"paper_title":{"en":"睡眠時ブラキシズムの基礎と最新の捉え方","ja":"睡眠時ブラキシズムの基礎と最新の捉え方"},"authors":{"en":[{"name":"Suzuki Yoshitaka"},{"name":"Okura Kazuo"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"鈴木 善貴"},{"name":"大倉 一夫"},{"name":"松香 芳三"}]},"publication_date":"2016-10","publication_name":{"en":"Journal of Oral and Sleep Medicine","ja":"睡眠口腔医学"},"volume":"Vol.3","number":"No.1","starting_page":"10","ending_page":"21","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.24695/josm.3.1_10"],"issn":["2188-6695"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:87, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/113900","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26868189","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84955303318&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=289006","label":"url"}],"paper_title":{"en":"Japan Prosthodontic Society position paper on occlusal discomfort syndrome","ja":"Japan Prosthodontic Society position paper on occlusal discomfort syndrome"},"authors":{"en":[{"name":"Tamaki K"},{"name":"Ishigaki S"},{"name":"Ogawa T"},{"name":"Oguchi H"},{"name":"Kato T"},{"name":"Suganuma T"},{"name":"Shimada A"},{"name":"Sadamori S"},{"name":"Tsukiyama Y"},{"name":"Nishikawa Y"},{"name":"Masumi S"},{"name":"Yamaguchi T"},{"name":"Aita H"},{"name":"Ono T"},{"name":"Kondo H"},{"name":"Tsukasaki H"},{"name":"Fueki K"},{"name":"Fujisawa M"},{"name":"Matsuka Yoshizo"},{"name":"Baba K"},{"name":"Koyano K"}],"ja":[{"name":"Tamaki K"},{"name":"Ishigaki S"},{"name":"Ogawa T"},{"name":"Oguchi H"},{"name":"Kato T"},{"name":"Suganuma T"},{"name":"Shimada A"},{"name":"Sadamori S"},{"name":"Tsukiyama Y"},{"name":"Nishikawa Y"},{"name":"Masumi S"},{"name":"Yamaguchi T"},{"name":"Aita H"},{"name":"Ono T"},{"name":"Kondo H"},{"name":"Tsukasaki H"},{"name":"Fueki K"},{"name":"Fujisawa M"},{"name":"松香 芳三"},{"name":"Baba K"},{"name":"Koyano K"}]},"description":{"en":"Dentists may encounter patients who present with a sense of a malocclusion but in whom no objective findings can be detected. For the patient who insists that there is occlusal discomfort, in the absence of evidence some dentists elect to perform an occlusal adjustment that not only fails to alleviate symptoms, and may, in fact, exacerbate the discomfort. The patient-dentist relationship is then likely compromised because of a lack of trust. In 2011, the Clinical Practice Guidelines Committee of the Japan Prosthodontic Society formulated guidelines for the management of occlusal discomfort. When formulating clinical practice guidelines, the committee bases their recommendations on information derived from scientific evidence. For \"occlusal dysesthesia,\" however, there are an insufficient number of high-quality papers related to the subject. Therefore, a consensus meeting was convened by the Japan Prosthodontic Society to examine evidence in the Japanese- and English-language literature and generate a multi-center survey to create an appropriate appellation for this condition. As a result of the consensus meeting and survey findings, this condition may be justifiably termed \"occlusal discomfort syndrome.\" The Japan Prosthodontics Society believes that identification of an umbrella term for occlusal discomfort might serve as a useful guide to formulating clinical practice guidelines in the future. This position paper represents summary findings in the literature combined with the results of a multicenter survey focused on dental occlusal treatment and the condition of patients who present with occlusal discomfort syndrome.","ja":"Dentists may encounter patients who present with a sense of a malocclusion but in whom no objective findings can be detected. For the patient who insists that there is occlusal discomfort, in the absence of evidence some dentists elect to perform an occlusal adjustment that not only fails to alleviate symptoms, and may, in fact, exacerbate the discomfort. The patient-dentist relationship is then likely compromised because of a lack of trust. In 2011, the Clinical Practice Guidelines Committee of the Japan Prosthodontic Society formulated guidelines for the management of occlusal discomfort. When formulating clinical practice guidelines, the committee bases their recommendations on information derived from scientific evidence. For \"occlusal dysesthesia,\" however, there are an insufficient number of high-quality papers related to the subject. Therefore, a consensus meeting was convened by the Japan Prosthodontic Society to examine evidence in the Japanese- and English-language literature and generate a multi-center survey to create an appropriate appellation for this condition. As a result of the consensus meeting and survey findings, this condition may be justifiably termed \"occlusal discomfort syndrome.\" The Japan Prosthodontics Society believes that identification of an umbrella term for occlusal discomfort might serve as a useful guide to formulating clinical practice guidelines in the future. This position paper represents summary findings in the literature combined with the results of a multicenter survey focused on dental occlusal treatment and the condition of patients who present with occlusal discomfort syndrome."},"publication_date":"2016-07","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.60","number":"No.3","starting_page":"156","ending_page":"166","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2015.11.002"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:88, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797047"},"force":{"see_also":[{"@id":"http://hdl.handle.net/10130/3982","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=289671","label":"url"}],"paper_title":{"en":"口腔ならびに呼吸器症状を呈した歯科用金属によるアレルギーの1例","ja":"口腔ならびに呼吸器症状を呈した歯科用金属によるアレルギーの1例"},"authors":{"en":[{"name":"Momota Yukihiro"},{"name":"Hosoki Maki"},{"name":"Ninomiya Masami"},{"name":"Takano Hideyuki"},{"name":"Matsuka Yoshizo"},{"name":"Azuma Masayuki"}],"ja":[{"name":"桃田 幸弘"},{"name":"細木 眞紀"},{"name":"二宮 雅美"},{"name":"高野 栄之"},{"name":"松香 芳三"},{"name":"東 雅之"}]},"publication_date":"2016-03","publication_name":{"en":"Journal of Japanese Society for Evidence and the Dental Professional","ja":"日本口腔検査学会雑誌"},"volume":"Vol.8","number":"No.1","starting_page":"39","ending_page":"44","languages":["jpn"],"referee":true,"identifiers":{"issn":["1883-3888"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:89, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111970","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26774509","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282680276696576/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84953449555&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=306060","label":"url"}],"paper_title":{"en":"Allergic contact dermatitis caused by titanium screws and dental implants","ja":"Allergic contact dermatitis caused by titanium screws and dental implants"},"authors":{"en":[{"name":"Hosoki Maki"},{"name":"Nishigawa Keisuke"},{"name":"Miyamoto Youji"},{"name":"Ohe Go"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"細木 眞紀"},{"name":"西川 啓介"},{"name":"宮本 洋二"},{"name":"大江 剛"},{"name":"松香 芳三"}]},"description":{"en":"Titanium has been considered to be a non-allergenic material. However, several studies have reported cases of metal allergy caused by titanium-containing materials. We describe a 69-year-old male for whom significant pathologic findings around dental implants had never been observed. He exhibited allergic symptoms (eczema) after orthopedic surgery. The titanium screws used in the orthopedic surgery that he underwent were removed 1 year later, but the eczema remained. After removal of dental implants, the eczema disappeared completely. Titanium is used not only for medical applications such as plastic surgery and/or dental implants, but also for paints, white pigments, photocatalysts, and various types of everyday goods. Most of the usage of titanium is in the form of titanium dioxide. This rapid expansion of titanium-containing products has increased percutaneous and permucosal exposure of titanium to the population. In general, allergic risk of titanium material is smaller than that of other metal materials. However, we suggest that pre-implant patients should be asked about a history of hypersensitivity reactions to metals, and patch testing should be recommended to patients who have experienced such reactions.","ja":"Titanium has been considered to be a non-allergenic material. However, several studies have reported cases of metal allergy caused by titanium-containing materials. We describe a 69-year-old male for whom significant pathologic findings around dental implants had never been observed. He exhibited allergic symptoms (eczema) after orthopedic surgery. The titanium screws used in the orthopedic surgery that he underwent were removed 1 year later, but the eczema remained. After removal of dental implants, the eczema disappeared completely. Titanium is used not only for medical applications such as plastic surgery and/or dental implants, but also for paints, white pigments, photocatalysts, and various types of everyday goods. Most of the usage of titanium is in the form of titanium dioxide. This rapid expansion of titanium-containing products has increased percutaneous and permucosal exposure of titanium to the population. In general, allergic risk of titanium material is smaller than that of other metal materials. However, we suggest that pre-implant patients should be asked about a history of hypersensitivity reactions to metals, and patch testing should be recommended to patients who have experienced such reactions."},"publication_date":"2016-01-08","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.60","number":"No.3","starting_page":"213","ending_page":"219","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2015.12.004"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:90, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/130005128732/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001205301164032/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=306066","label":"url"}],"paper_title":{"en":"\"Occlusal consideration for fixed implant prosthesis in mandibular posterior region\"","ja":"下顎大臼歯欠損に対しインプラント支持固定性補綴装置による治療介入時に付与すべき咬合様式"},"authors":{"en":[{"name":"近藤 尚知"},{"name":"尾澤 昌悟"},{"name":"澤瀬 隆"},{"name":"横山 敦郎"},{"name":"関根 秀志"},{"name":"舞田 健夫"},{"name":"鮎川 保則"},{"name":"中野 環"},{"name":"久保 隆靖"},{"name":"細川 隆司"},{"name":"Tomotake Yoritoki"},{"name":"城戸 寛史"},{"name":"越智 守生"},{"name":"塩田 真"},{"name":"尾関 雅彦"},{"name":"西村 正宏"},{"name":"前田 芳信"},{"name":"會田 英紀"},{"name":"玉置 勝司"},{"name":"笛木 賢治"},{"name":"塚崎 弘明"},{"name":"小野 高裕"},{"name":"松下 恭之"},{"name":"Matsuka Yoshizo"},{"name":"水口 一"},{"name":"桑鶴 利香"},{"name":"山下 秀一郎"},{"name":"飯塚 知明"},{"name":"馬場 一美"},{"name":"藤澤 政紀"},{"name":"古谷野 潔"},{"name":"矢谷 博文"}],"ja":[{"name":"近藤 尚知"},{"name":"尾澤 昌悟"},{"name":"澤瀬 隆"},{"name":"横山 敦郎"},{"name":"関根 秀志"},{"name":"舞田 健夫"},{"name":"鮎川 保則"},{"name":"中野 環"},{"name":"久保 隆靖"},{"name":"細川 隆司"},{"name":"友竹 偉則"},{"name":"城戸 寛史"},{"name":"越智 守生"},{"name":"塩田 真"},{"name":"尾関 雅彦"},{"name":"西村 正宏"},{"name":"前田 芳信"},{"name":"會田 英紀"},{"name":"玉置 勝司"},{"name":"笛木 賢治"},{"name":"塚崎 弘明"},{"name":"小野 高裕"},{"name":"松下 恭之"},{"name":"松香 芳三"},{"name":"水口 一"},{"name":"桑鶴 利香"},{"name":"山下 秀一郎"},{"name":"飯塚 知明"},{"name":"馬場 一美"},{"name":"藤澤 政紀"},{"name":"古谷野 潔"},{"name":"矢谷 博文"}]},"description":{"en":"Clinical guidelines or definitive criteria for \"Occlusal consideration for fixed implant prosthesis in mandibular posterior region\" have not been established yet although the dental implant is an essential treatment option for current prosthetic dentistry. This position paper aimed to propose a critical recommendation and consequently indicate a tentative practice guideline. In this paper, the first and second molar missing in the mandible was assumed as the most typical partial edentulous jaw. A panel of clinical experts concerning dental implant practice was selected from the members of the Japan Prosthodontic Society, and a meeting was held to collect clinical data obtained from daily practice and to estimate expert opinions. As a result, general remarks were presented regarding shapes of prostheses, position and number of occlusal contact points, occlusal contact during lateral excursion, displacement of periodontal ligament, and materials of occlusal surface. However, the expert opinions described above have not been supported by clinical evidence. Moreover, neither the effect of those therapies nor long-term prognosis has been thoroughly investigated. Thus, further study for collecting the clinical evidences is required to formulate the clinical guideline.","ja":"インプラント治療が補綴歯科臨床の場で必要不可欠となった今日においても,未だ「インプラント支持固定性補綴装置に付与すべき咬合様式」のガイドラインまたは明確な基準は示されていない.本ポジションペーパーにおいては,その推奨されるべき一定の基準を示し,臨床上の指針として提案することを目的とした.本稿では,典型的な欠損形態である下顎大臼歯部欠損にインプラント支持補綴装置を装着した場合を想定している.口腔インプラントを適用した治療に関して経験豊富なエキスパートパネルを,(公社)日本補綴歯科学会会員から選出し,臨床の現場における事象を検証した結果として得られた意見を集積し,パネル会議で検討した.その結果,補綴装置の形態,咬合接触点の位置と数,側方運動時の咬合接触の有無,歯根膜の変位量の考慮,補綴装置咬合面の材料等に関する知見が得られ,推奨される一定の基準が示された.しかしながら,上記内容は明確な根拠に支持されるものではなく,治療効果と術後経過に関する研究が不十分であり,今後さらなる知見の集積と検証のもとに,ガイドラインを策定すべきである."},"publication_date":"2016-01","publication_name":{"en":"Annals of Japan Prosthodontic Society","ja":"日本補綴歯科学会誌"},"volume":"Vol.8","number":"No.1","starting_page":"1","ending_page":"9","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.2186/ajps.8.1"],"issn":["1883-4426"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:91, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26527205","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84961126869&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=305284","label":"url"}],"paper_title":{"en":"Sleep bruxism frequency and platelet serotonin transporter activities in young adult subjects","ja":"Sleep bruxism frequency and platelet serotonin transporter activities in young adult subjects"},"authors":{"en":[{"name":"Hajime Minakuchi"},{"name":"Chieko Sogawa"},{"name":"Haruna Miki"},{"name":"Emilio S Hara"},{"name":"Kenji Maekawa"},{"name":"Norio Sogawa"},{"name":"Shigeharu Kitayama"},{"name":"Matsuka Yoshizo"},{"name":"Clenn T Clark"},{"name":"Takuo Kuboki"}],"ja":[{"name":"Hajime Minakuchi"},{"name":"Chieko Sogawa"},{"name":"Haruna Miki"},{"name":"Emilio S Hara"},{"name":"Kenji Maekawa"},{"name":"Norio Sogawa"},{"name":"Shigeharu Kitayama"},{"name":"松香 芳三"},{"name":"Clenn T Clark"},{"name":"Takuo Kuboki"}]},"description":{"en":"To evaluate correlations between serotonin transporter (SERT) uptake ability in human peripheral platelets and sleep bruxism (SB) frequency. Subjects were consecutively recruited from sixth-year students at Okayama University Dental School. Subjects were excluded if they (1) were receiving orthodontic treatment, (2) had a dermatological disease, (3) had taken an antidepressant within 6 months, or (4) had used an oral appliance within 6 months. SB frequency was determined as the summary score of three consecutive night assessments using a self-contained electromyography detector/analyzer in their home. Fasting peripheral venous blood samples were collected in the morning following the final SB assessment. SERT amount and platelet number were quantified via an ELISA assay and flow cytometry, respectively. Functional SERT characterization, 5-hydroxytryptamine (5-HT) uptake, maximum velocity (V max), and an affinity constant (K m ) were assessed with a [(3)H] 5-HT uptake assay. The correlations between these variables and SB level were evaluated. Among 50 eligible subjects (26 males, mean age 25.4 ± 2.41 years), 7 were excluded because of venipuncture failure, smoking, and alcohol intake during the experimental period. A small but significant negative correlation between SB level and [(3)H] 5-HT uptake was observed (Spearman's correlation R (2) = 0.063, p = 0.04). However, there were no significant correlations between SB level and total platelet amount, SERT, V max, and K m values (p = 0.08, 0.12, 0.71, and 0.68, respectively). Platelet serotonin uptake is significantly associated with SB frequency, yet only explains a small amount of SB variability.","ja":"To evaluate correlations between serotonin transporter (SERT) uptake ability in human peripheral platelets and sleep bruxism (SB) frequency. Subjects were consecutively recruited from sixth-year students at Okayama University Dental School. Subjects were excluded if they (1) were receiving orthodontic treatment, (2) had a dermatological disease, (3) had taken an antidepressant within 6 months, or (4) had used an oral appliance within 6 months. SB frequency was determined as the summary score of three consecutive night assessments using a self-contained electromyography detector/analyzer in their home. Fasting peripheral venous blood samples were collected in the morning following the final SB assessment. SERT amount and platelet number were quantified via an ELISA assay and flow cytometry, respectively. Functional SERT characterization, 5-hydroxytryptamine (5-HT) uptake, maximum velocity (V max), and an affinity constant (K m ) were assessed with a [(3)H] 5-HT uptake assay. The correlations between these variables and SB level were evaluated. Among 50 eligible subjects (26 males, mean age 25.4 ± 2.41 years), 7 were excluded because of venipuncture failure, smoking, and alcohol intake during the experimental period. A small but significant negative correlation between SB level and [(3)H] 5-HT uptake was observed (Spearman's correlation R (2) = 0.063, p = 0.04). However, there were no significant correlations between SB level and total platelet amount, SERT, V max, and K m values (p = 0.08, 0.12, 0.71, and 0.68, respectively). Platelet serotonin uptake is significantly associated with SB frequency, yet only explains a small amount of SB variability."},"publication_date":"2015-11-02","publication_name":{"en":"Sleep & Breathing = Schlaf & Atmung","ja":"Sleep & Breathing = Schlaf & Atmung"},"volume":"Vol.20","number":"No.1","starting_page":"271","ending_page":"276","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s11325-015-1281-0"],"issn":["1522-1709"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:92, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://cir.nii.ac.jp/crid/1390001205521269248/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=298990","label":"url"}],"paper_title":{"en":"根尖性歯周炎に起因した放射線性下顎骨骨髄炎に対して保存的治療を行い良好な経過を得た一症例","ja":"根尖性歯周炎に起因した放射線性下顎骨骨髄炎に対して保存的治療を行い良好な経過を得た一症例"},"authors":{"en":[{"name":"工藤 値英子"},{"name":"水川 展吉"},{"name":"中川 沙紀"},{"name":"柳 文修"},{"name":"江口 元治"},{"name":"Matsuka Yoshizo"},{"name":"吉岡 裕也"},{"name":"高柴 正悟"}],"ja":[{"name":"工藤 値英子"},{"name":"水川 展吉"},{"name":"中川 沙紀"},{"name":"柳 文修"},{"name":"江口 元治"},{"name":"松香 芳三"},{"name":"吉岡 裕也"},{"name":"高柴 正悟"}]},"publication_date":"2015-10","publication_name":{"en":"The Japanese Journal of Conservative Dentistry","ja":"日本歯科保存学雑誌"},"volume":"Vol.58","number":"No.5","starting_page":"425","ending_page":"434","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11471/shikahozon.58.425"],"issn":["0387-2343"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:93, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111994","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26342527","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84944167103&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=297171","label":"url"}],"paper_title":{"en":"Masticatory performance alters stress relief effect of gum chewing","ja":"Masticatory performance alters stress relief effect of gum chewing"},"authors":{"en":[{"name":"Nishigawa Keisuke"},{"name":"Suzuki Yoshitaka"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"西川 啓介"},{"name":"鈴木 善貴"},{"name":"松香 芳三"}]},"description":{"en":"We evaluated the effects of gum chewing on the response to psychological stress induced by a calculation task and investigated the relationship between this response and masticatory performance. Nineteen healthy adult volunteers without dental problems undertook the Uchida-Kraepelin (UK) test (30min of reiterating additions of one-digit numbers). Before and immediately after the test, saliva samples were collected from the sublingual area of the participants. Three min after the UK test, the participants were made to chew flavorless gum for 3min, and the final saliva samples were collected 10min after the UK test. The experiment was performed without gum chewing on a different day. Masticatory performance was evaluated using color-changing chewing gum. Salivary CgA levels at immediately and 10min after the UK test were compared with and without gum chewing condition. Two-way repeated measures analysis of variance revealed significant interaction between gum chewing condition and changes in CgA levels during post 10min UK test period. A significant correlation was found between changes in CgA levels and masticatory performance in all participants. Our results indicate that gum chewing may relieve stress responses; however, high masticatory performance is required to achieve this effect.","ja":"We evaluated the effects of gum chewing on the response to psychological stress induced by a calculation task and investigated the relationship between this response and masticatory performance. Nineteen healthy adult volunteers without dental problems undertook the Uchida-Kraepelin (UK) test (30min of reiterating additions of one-digit numbers). Before and immediately after the test, saliva samples were collected from the sublingual area of the participants. Three min after the UK test, the participants were made to chew flavorless gum for 3min, and the final saliva samples were collected 10min after the UK test. The experiment was performed without gum chewing on a different day. Masticatory performance was evaluated using color-changing chewing gum. Salivary CgA levels at immediately and 10min after the UK test were compared with and without gum chewing condition. Two-way repeated measures analysis of variance revealed significant interaction between gum chewing condition and changes in CgA levels during post 10min UK test period. A significant correlation was found between changes in CgA levels and masticatory performance in all participants. Our results indicate that gum chewing may relieve stress responses; however, high masticatory performance is required to achieve this effect."},"publication_date":"2015-10","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.59","number":"No.4","starting_page":"262","ending_page":"267","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2015.07.004"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:94, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/110096","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26248078","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84940830023&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=297100","label":"url"}],"paper_title":{"en":"Cross-excitation in peripheral sensory ganglia is associated with pain transmission","ja":"Cross-excitation in peripheral sensory ganglia is associated with pain transmission"},"authors":{"en":[{"name":"Omoto Katsuhiro"},{"name":"Maruhama K"},{"name":"Terayama R"},{"name":"Yamamoto Yumiko"},{"name":"Matsushita Osam"},{"name":"Sugimoto Tomosada"},{"name":"Oguma Keiji"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Omoto Katsuhiro"},{"name":"Maruhama K"},{"name":"Terayama R"},{"name":"Yamamoto Yumiko"},{"name":"Matsushita Osam"},{"name":"Sugimoto Tomosada"},{"name":"Oguma Keiji"},{"name":"松香 芳三"}]},"description":{"en":"Despite the absence of synaptic contacts, cross-excitation of neurons in sensory ganglia during signal transmission is considered to be chemically mediated and appears increased in chronic pain states. In this study, we modulated neurotransmitter release in sensory neurons by direct application of type A botulinum neurotoxin (BoNT/A) to sensory ganglia in an animal model of neuropathic pain and evaluated the effect of this treatment on nocifensive. Unilateral sciatic nerve entrapment (SNE) reduced the ipsilateral hindpaw withdrawal threshold to mechanical stimulation and reduced hindpaw withdrawal latency to thermal stimulation. Direct application of BoNT/A to the ipsilateral L4 dorsal root ganglion (DRG) was localized in the cell bodies of the DRG and reversed the SNE-induced decreases in withdrawal thresholds within 2 days of BoNT/A administration. Results from this study suggest that neurotransmitter release within sensory ganglia is involved in the regulation of pain-related signal transmission.","ja":"Despite the absence of synaptic contacts, cross-excitation of neurons in sensory ganglia during signal transmission is considered to be chemically mediated and appears increased in chronic pain states. In this study, we modulated neurotransmitter release in sensory neurons by direct application of type A botulinum neurotoxin (BoNT/A) to sensory ganglia in an animal model of neuropathic pain and evaluated the effect of this treatment on nocifensive. Unilateral sciatic nerve entrapment (SNE) reduced the ipsilateral hindpaw withdrawal threshold to mechanical stimulation and reduced hindpaw withdrawal latency to thermal stimulation. Direct application of BoNT/A to the ipsilateral L4 dorsal root ganglion (DRG) was localized in the cell bodies of the DRG and reversed the SNE-induced decreases in withdrawal thresholds within 2 days of BoNT/A administration. Results from this study suggest that neurotransmitter release within sensory ganglia is involved in the regulation of pain-related signal transmission."},"publication_date":"2015-08-04","publication_name":{"en":"Toxins","ja":"Toxins"},"volume":"Vol.7","number":"No.8","starting_page":"2906","ending_page":"2917","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/toxins7082906"],"issn":["2072-6651"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:95, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84931576617&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=293746","label":"url"}],"paper_title":{"en":"A preliminary investigation of reproducibility of EMG signals during daytime masticatory muscle activity using a portable EMG logging device","ja":"A preliminary investigation of reproducibility of EMG signals during daytime masticatory muscle activity using a portable EMG logging device"},"authors":{"en":[{"name":"Omoto Katsuhiro"},{"name":"Shigemoto Shuji"},{"name":"Suzuki Yoshitaka"},{"name":"Nakamura Mayumi"},{"name":"Okura Kazuo"},{"name":"Nishigawa Keisuke"},{"name":"Goto Nami"},{"name":"Rodis Omar"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Omoto Katsuhiro"},{"name":"重本 修伺"},{"name":"鈴木 善貴"},{"name":"中村 真弓"},{"name":"大倉 一夫"},{"name":"西川 啓介"},{"name":"Goto Nami"},{"name":"ロディス オマー"},{"name":"松香 芳三"}]},"publication_date":"2015-08","publication_name":{"en":"Journal of Electromyography and Kinesiology","ja":"Journal of Electromyography and Kinesiology"},"volume":"Vol.25","number":"No.4","starting_page":"603","ending_page":"611","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jelekin.2015.04.012"],"issn":["1050-6411"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:96, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26077377","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84937633822&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=293318","label":"url"}],"paper_title":{"en":"A longitudinal retrospective study of the analysis of the risk factors of implant failure by the application of generalized estimating equations","ja":"A longitudinal retrospective study of the analysis of the risk factors of implant failure by the application of generalized estimating equations"},"authors":{"en":[{"name":"Noda K"},{"name":"Arakawa H"},{"name":"Kimura-Ono A"},{"name":"Yamazaki S"},{"name":"Hara ES"},{"name":"Sonoyama W"},{"name":"Maekawa K"},{"name":"Okura Kazuo"},{"name":"Shintani A"},{"name":"Matsuka Yoshizo"},{"name":"Kuboki T"}],"ja":[{"name":"Noda K"},{"name":"Arakawa H"},{"name":"Kimura-Ono A"},{"name":"Yamazaki S"},{"name":"Hara ES"},{"name":"Sonoyama W"},{"name":"Maekawa K"},{"name":"大倉 一夫"},{"name":"Shintani A"},{"name":"松香 芳三"},{"name":"Kuboki T"}]},"description":{"en":"Many studies have identified risk factors for dental implant failure, although few have investigated the correlation among implant fixtures within single patients. A better analytical method may include repeated measures analysis including generalized estimating equations (GEE). This retrospective cohort study aimed to (1) identify the risk factors for failure of dental implantation and (2) evaluate an analytical method using GEE analysis. We analyzed data on early and late implant failures in 296 patients providing 721 rough surface dental implants (2.44 implants per patient). Potential predictors of implant failure included age, gender, smoking, location of implant, use of bone augmentation, number of remaining teeth, opposing tooth condition, fixture length, fixture diameter and type of suprastructure (fixed or removable partial denture). The likelihood of early and late implant failure was estimated by GEE. The early failure rate was 1.5% (11/721 implants, 7/296 patients) and the 10-year cumulative survival rate was 94.0% (7/710 implants, 5/293 patients). The GEE analysis revealed that a significant risk factor for early implant failure was smoking (p<0.01), whereas significant risk factors for late failure were maxillary implant (p=0.02), posterior implant (p<0.01), number of remaining teeth (≥20) (p<0.01), opposing unit being a removable partial denture or nothing (p=0.04) and having a removable type suprastructure (p<0.01). GEE analysis showed that smoking was a risk factor for early implant failure, and several risk factors were identified for late implant failure.","ja":"Many studies have identified risk factors for dental implant failure, although few have investigated the correlation among implant fixtures within single patients. A better analytical method may include repeated measures analysis including generalized estimating equations (GEE). This retrospective cohort study aimed to (1) identify the risk factors for failure of dental implantation and (2) evaluate an analytical method using GEE analysis. We analyzed data on early and late implant failures in 296 patients providing 721 rough surface dental implants (2.44 implants per patient). Potential predictors of implant failure included age, gender, smoking, location of implant, use of bone augmentation, number of remaining teeth, opposing tooth condition, fixture length, fixture diameter and type of suprastructure (fixed or removable partial denture). The likelihood of early and late implant failure was estimated by GEE. The early failure rate was 1.5% (11/721 implants, 7/296 patients) and the 10-year cumulative survival rate was 94.0% (7/710 implants, 5/293 patients). The GEE analysis revealed that a significant risk factor for early implant failure was smoking (p<0.01), whereas significant risk factors for late failure were maxillary implant (p=0.02), posterior implant (p<0.01), number of remaining teeth (≥20) (p<0.01), opposing unit being a removable partial denture or nothing (p=0.04) and having a removable type suprastructure (p<0.01). GEE analysis showed that smoking was a risk factor for early implant failure, and several risk factors were identified for late implant failure."},"publication_date":"2015-08","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.59","number":"No.3","starting_page":"178","ending_page":"184","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2015.04.003"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:97, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25944119","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84937640007&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=294646","label":"url"}],"paper_title":{"en":"Diagnosis and treatment for obstructive sleep apnea: Fundamental and clinical knowledge in obstructive sleep apnea","ja":"Diagnosis and treatment for obstructive sleep apnea: Fundamental and clinical knowledge in obstructive sleep apnea"},"authors":{"en":[{"name":"Shigemoto Shuji"},{"name":"Shigeta Yuko"},{"name":"Nejima Jun"},{"name":"Ogawa Takumi"},{"name":"Matsuka Yoshizo"},{"name":"Clark T. Glenn"}],"ja":[{"name":"重本 修伺"},{"name":"Shigeta Yuko"},{"name":"Nejima Jun"},{"name":"Ogawa Takumi"},{"name":"松香 芳三"},{"name":"Clark T. Glenn"}]},"description":{"en":"This review article covers the diagnosis and treatment of obstructive sleep apnea (OSA) from a dental perspective. It addresses the issue of when and how to screen for and then, if indicated, refer the patient for a more comprehensive. Our focus in this article was on identifying current unanswered questions that relevant to OSA problems that dental scientists have to pursue and on providing valuable information on that problems, consequently the previous studies which investigated or reviewed the diagnosis and treatment of OSA were included. In addition, we included studies on jaw movements during sleep and on the use of a lateral cephalometric film related to the diagnosis and treatment of OSA. The role of portable sleep monitoring devices versus full laboratory polysomnography is discussed. This review also describes what is known about the efficacy of mandibular advancement devices and when and how they fit in to a treatment program for a patient with obstructive sleep apnea. Finally some basic research is presented on jaw movements during sleep and how a lateral cephalometric film can be used to assess the changes of the airway with body posture and head posture. This article provides the valuable suggestions for the clinical questions in the diagnosis and treatment of OSA.","ja":"This review article covers the diagnosis and treatment of obstructive sleep apnea (OSA) from a dental perspective. It addresses the issue of when and how to screen for and then, if indicated, refer the patient for a more comprehensive. Our focus in this article was on identifying current unanswered questions that relevant to OSA problems that dental scientists have to pursue and on providing valuable information on that problems, consequently the previous studies which investigated or reviewed the diagnosis and treatment of OSA were included. In addition, we included studies on jaw movements during sleep and on the use of a lateral cephalometric film related to the diagnosis and treatment of OSA. The role of portable sleep monitoring devices versus full laboratory polysomnography is discussed. This review also describes what is known about the efficacy of mandibular advancement devices and when and how they fit in to a treatment program for a patient with obstructive sleep apnea. Finally some basic research is presented on jaw movements during sleep and how a lateral cephalometric film can be used to assess the changes of the airway with body posture and head posture. This article provides the valuable suggestions for the clinical questions in the diagnosis and treatment of OSA."},"publication_date":"2015-07","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.59","number":"No.3","starting_page":"161","ending_page":"171","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2015.04.002"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:98, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111968","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25838013","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=283427","label":"url"}],"paper_title":{"en":"Effects of team-based learning on fixed prosthodontic education in Japan","ja":"Effects of team-based learning on fixed prosthodontic education in Japan"},"authors":{"en":[{"name":"Takeuchi Hisahiro"},{"name":"Omoto K"},{"name":"Okura Kazuo"},{"name":"Tajima Toyoko"},{"name":"Suzuki Yoshitaka"},{"name":"Hosoki Maki"},{"name":"Kori Motoharu"},{"name":"Shigemoto Shuji"},{"name":"Miyagi Mayu"},{"name":"Nishigawa Keisuke"},{"name":"Rodis Omar"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"竹内 久裕"},{"name":"Omoto K"},{"name":"大倉 一夫"},{"name":"田島 登誉子"},{"name":"鈴木 善貴"},{"name":"細木 眞紀"},{"name":"郡 元治"},{"name":"重本 修伺"},{"name":"宮城 麻友"},{"name":"西川 啓介"},{"name":"ロディス オマー"},{"name":"松香 芳三"}]},"description":{"en":"The aims of this study were to evaluate the quality of team-based learning (TBL) in prosthodontics education for fourth-year dental students at Tokushima University School of Dentistry and to compare this teaching method with traditional lecture-based delivery. Participants in the study were 36 students (22 males and 14 females) who attended the TBL-style fixed prosthodontics course. Ten 60-minute classes were held. The first three were traditional lecture-style classes and were followed by one class introducing the TBL style. The remaining six classes constituted the TBL-format fixed prosthodontics course. The effectiveness of TBL was evaluated through student questionnaires at the end of each class and the results of the term-end examination. The questionnaire revealed high student approval for TBL-style learning, and active group discussion among students during TBL was a key factor in these ratings. In the results of the term-end examination, there were significantly higher scores on the questions that covered TBL-taught material than those covering traditional lecture-taught topics. The results of this study suggest that TBL-style lecture was more effective than traditional-style lecture for teaching fixed prosthodontics and that TBL was a more efficient mode of delivering dental education than traditional lecture-based teaching.","ja":"The aims of this study were to evaluate the quality of team-based learning (TBL) in prosthodontics education for fourth-year dental students at Tokushima University School of Dentistry and to compare this teaching method with traditional lecture-based delivery. Participants in the study were 36 students (22 males and 14 females) who attended the TBL-style fixed prosthodontics course. Ten 60-minute classes were held. The first three were traditional lecture-style classes and were followed by one class introducing the TBL style. The remaining six classes constituted the TBL-format fixed prosthodontics course. The effectiveness of TBL was evaluated through student questionnaires at the end of each class and the results of the term-end examination. The questionnaire revealed high student approval for TBL-style learning, and active group discussion among students during TBL was a key factor in these ratings. In the results of the term-end examination, there were significantly higher scores on the questions that covered TBL-taught material than those covering traditional lecture-taught topics. The results of this study suggest that TBL-style lecture was more effective than traditional-style lecture for teaching fixed prosthodontics and that TBL was a more efficient mode of delivering dental education than traditional lecture-based teaching."},"publication_date":"2015-04","publication_name":{"en":"Journal of Dental Education","ja":"Journal of Dental Education"},"volume":"Vol.79","number":"No.4","starting_page":"417","ending_page":"423","languages":["eng"],"referee":true,"identifiers":{"issn":["1930-7837"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:99, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/120005823512/","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109857","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1050564287418442752/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=289007","label":"url"}],"paper_title":{"en":"Introduction and Effects of Team-Based Learning on Prosthodontic Education","ja":"歯科補綴学授業におけるTeam-Based Learningの導入とその効果"},"authors":{"en":[{"name":"大本 勝弘"},{"name":"Okura Kazuo"},{"name":"Tajima Toyoko"},{"name":"Suzuki Yoshitaka"},{"name":"Hosoki Maki"},{"name":"Kori Motoharu"},{"name":"Shigemoto Shuji"},{"name":"Miyagi Mayu"},{"name":"Nishigawa Keisuke"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"大本 勝弘"},{"name":"大倉 一夫"},{"name":"田島 登誉子"},{"name":"鈴木 善貴"},{"name":"細木 眞紀"},{"name":"郡 元治"},{"name":"重本 修伺"},{"name":"宮城 麻友"},{"name":"西川 啓介"},{"name":"松香 芳三"}]},"description":{"en":"Team-Based Learning (TBL) was introduced into our prosthodontic education for thirdyear dental school students. Forty students (26 males and 14 females) of Tokushima University School of Dentistry attended the TBL-style fixed prosthodontic course. A total of fifteen classes (60 minutes each), which started with six conventional lecture-style classes followed by 8 TBL-style classes, were held. The effectiveness of TBL was evaluated with student questionnaires at the end of each class and with the results of the term-end examination. The results of the questionnaire on some questions and term-end examination exhibited higher score for the TBL. The results of this study showed that TBL-style classes were more effective than that of the conventional lecture-style classes for the fixed prosthodontic course.","ja":"Team-Based Learning (TBL) was introduced into our prosthodontic education for thirdyear dental school students. Forty students (26 males and 14 females) of Tokushima University School of Dentistry attended the TBL-style fixed prosthodontic course. A total of fifteen classes (60 minutes each), which started with six conventional lecture-style classes followed by 8 TBL-style classes, were held. The effectiveness of TBL was evaluated with student questionnaires at the end of each class and with the results of the term-end examination. The results of the questionnaire on some questions and term-end examination exhibited higher score for the TBL. The results of this study showed that TBL-style classes were more effective than that of the conventional lecture-style classes for the fixed prosthodontic course."},"publication_date":"2015-02-20","publication_name":{"en":"Journal of Oral Health and Biosciences","ja":"Journal of Oral Health and Biosciences"},"volume":"Vol.27","number":"No.2","starting_page":"81","ending_page":"87","languages":["jpn"],"referee":true,"identifiers":{"issn":["2188-7888"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:100, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111992","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84925145449&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=289008","label":"url"}],"paper_title":{"en":"Basic research and clinical investigations of the neural basis of orofacial pain","ja":"Basic research and clinical investigations of the neural basis of orofacial pain"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Iwata Koichi"},{"name":"Terayama Ryuji"},{"name":"Imamura Yoshiki"},{"name":"Maruhama Kotaro"},{"name":"Shinoda Masamichi"},{"name":"Tsuboi Yoshiyuki"},{"name":"Kondo Masahiro"},{"name":"Honda Kuniya"},{"name":"Katagiri Ayano"},{"name":"Sugimoto Tomosada"}],"ja":[{"name":"松香 芳三"},{"name":"Iwata Koichi"},{"name":"Terayama Ryuji"},{"name":"Imamura Yoshiki"},{"name":"Maruhama Kotaro"},{"name":"Shinoda Masamichi"},{"name":"Tsuboi Yoshiyuki"},{"name":"Kondo Masahiro"},{"name":"Honda Kuniya"},{"name":"Katagiri Ayano"},{"name":"Sugimoto Tomosada"}]},"publication_date":"2015-02","publication_name":{"en":"Journal of Oral Biosciences","ja":"Journal of Oral Biosciences"},"volume":"Vol.57","number":"No.1","starting_page":"27","ending_page":"36","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.job.2014.09.001"],"issn":["1349-0079"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:101, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://ci.nii.ac.jp/naid/40020380099/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520572357908139520/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=290633","label":"url"}],"paper_title":{"en":"Establishment of a method for measuring and analyzing various bio-information during a sequence of feeding : Development of a measuring system","ja":"摂食・咀嚼・嚥下過程における各種生体情報の記録解析法の開発 ―測定システムの開発―"},"authors":{"en":[{"name":"Shigemoto Shuji"},{"name":"Tajima Toyoko"},{"name":"Suzuki Yoshitaka"},{"name":"Okura Kazuo"},{"name":"井川 知子"},{"name":"小川 匠"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"重本 修伺"},{"name":"田島 登誉子"},{"name":"鈴木 善貴"},{"name":"大倉 一夫"},{"name":"井川 知子"},{"name":"小川 匠"},{"name":"松香 芳三"}]},"publication_date":"2014-12","publication_name":{"en":"The Journal of Japan Association of Oral Rehabilitation","ja":"日本口腔リハビリテーション学会雑誌"},"volume":"Vol.27","number":"No.1","starting_page":"29","ending_page":"37","languages":["jpn"],"referee":true,"identifiers":{"issn":["2186-2052"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:102, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://ci.nii.ac.jp/naid/40020380074/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520572357389487232/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=290632","label":"url"}],"paper_title":{"en":"Development of a new method for understanding visually slight tooth movements with six-degree-of-freedom","ja":"歯の6自由度運動を視覚的に理解する手法の開発"},"authors":{"en":[{"name":"Tajima Toyoko"},{"name":"Shigemoto Shuji"},{"name":"Suzuki Yoshitaka"},{"name":"Okura Kazuo"},{"name":"Rodis Omar"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"田島 登誉子"},{"name":"重本 修伺"},{"name":"鈴木 善貴"},{"name":"大倉 一夫"},{"name":"ロディス オマー"},{"name":"松香 芳三"}]},"publication_date":"2014-12","publication_name":{"en":"The Journal of Japan Association of Oral Rehabilitation","ja":"日本口腔リハビリテーション学会雑誌"},"volume":"Vol.27","number":"No.1","starting_page":"16","ending_page":"23","languages":["jpn"],"referee":true,"identifiers":{"issn":["2186-2052"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:103, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://cir.nii.ac.jp/crid/1390282679398085120/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=289441","label":"url"}],"paper_title":{"en":"咬合違和感を訴える患者の実態に関する多施設実態調査","ja":"咬合違和感を訴える患者の実態に関する多施設実態調査"},"authors":{"en":[{"name":"澁谷 智明"},{"name":"和気 裕之"},{"name":"玉置 勝司"},{"name":"島田 淳"},{"name":"古谷野 潔"},{"name":"鱒見 進一"},{"name":"窪木 拓男"},{"name":"皆木 省吾"},{"name":"貞森 紳丞"},{"name":"矢谷 博文"},{"name":"藤澤 政紀"},{"name":"林 勝彦"},{"name":"玉井 和樹"},{"name":"成田 紀之"},{"name":"原 節宏"},{"name":"馬場 一美"},{"name":"尾口 仁志"},{"name":"金村 清孝"},{"name":"山口 泰彦"},{"name":"西川 洋二"},{"name":"塚原 宏泰"},{"name":"Matsuka Yoshizo"},{"name":"葉山 莉香"}],"ja":[{"name":"澁谷 智明"},{"name":"和気 裕之"},{"name":"玉置 勝司"},{"name":"島田 淳"},{"name":"古谷野 潔"},{"name":"鱒見 進一"},{"name":"窪木 拓男"},{"name":"皆木 省吾"},{"name":"貞森 紳丞"},{"name":"矢谷 博文"},{"name":"藤澤 政紀"},{"name":"林 勝彦"},{"name":"玉井 和樹"},{"name":"成田 紀之"},{"name":"原 節宏"},{"name":"馬場 一美"},{"name":"尾口 仁志"},{"name":"金村 清孝"},{"name":"山口 泰彦"},{"name":"西川 洋二"},{"name":"塚原 宏泰"},{"name":"松香 芳三"},{"name":"葉山 莉香"}]},"publication_date":"2014-12","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.26","number":"No.3","starting_page":"196","ending_page":"203","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11246/gakukansetsu.26.196"],"issn":["0915-3004"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:104, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/114762","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25404383","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=288936","label":"url"}],"paper_title":{"en":"A proposed core curriculum for dental English education in Japan.","ja":"A proposed core curriculum for dental English education in Japan."},"authors":{"en":[{"name":"Rodis Omar"},{"name":"Barroga Edward"},{"name":"Barron Patrick J"},{"name":"Hobbs James"},{"name":"Jayawardena A. Jayanetti"},{"name":"Kageyama Ikuo"},{"name":"Kalubi Bukasa"},{"name":"Langham Clive"},{"name":"Matsuka Yoshizo"},{"name":"Miyake Yoichiro"},{"name":"Seki Naoko"},{"name":"Oka Hiroko"},{"name":"Peters Martin"},{"name":"Shibata Yo"},{"name":"Stegaroiu Roxana"},{"name":"Suzuki Kazuyoshi"},{"name":"Takahashi Shigeru"},{"name":"Tsuchiya Hironori"},{"name":"Yoshida Toshiko"},{"name":"Yoshimoto Katsuhiko"}],"ja":[{"name":"ロディス オマー"},{"name":"Barroga Edward"},{"name":"Barron Patrick J"},{"name":"Hobbs James"},{"name":"Jayawardena A. Jayanetti"},{"name":"Kageyama Ikuo"},{"name":"カルビ ブカサ"},{"name":"Langham Clive"},{"name":"松香 芳三"},{"name":"三宅 洋一郎"},{"name":"Seki Naoko"},{"name":"Oka Hiroko"},{"name":"Peters Martin"},{"name":"Shibata Yo"},{"name":"Stegaroiu Roxana"},{"name":"Suzuki Kazuyoshi"},{"name":"Takahashi Shigeru"},{"name":"Tsuchiya Hironori"},{"name":"吉田 登志子"},{"name":"吉本 勝彦"}]},"description":{"en":"Globalization of the professions has become a necessity among schools and universities across the world. It has affected the medical and dental professions in terms of curriculum design and student and patient needs. In Japan, where medicine and dentistry are taught mainly in the Japanese language, profession-based courses in English, known as Medical English and Dental English, have been integrated into the existing curriculum among its 83 medical and 29 dental schools. Unfortunately, there is neither a core curriculum nor a model syllabus for these courses. This report is based on a survey, two discussion forums, a workshop, and finally, the drafting of a proposed core curriculum for dental English approved by consensus of the participants from each university. The core curriculum covers the theoretical aspects, including dental English terms and oral pathologies; and practical aspects, including blended learning and dentist-patient communication. It is divided into modules and is recommended to be offered for at least two semesters. The core curriculum is expected to guide curriculum developers in schools where dental English courses are yet to be offered or are still in their early development. It may also serve as a model curriculum to medical and dental schools in countries in Asia, Europe, Africa, and Central and South America, where English is not the medium of instruction.","ja":"Globalization of the professions has become a necessity among schools and universities across the world. It has affected the medical and dental professions in terms of curriculum design and student and patient needs. In Japan, where medicine and dentistry are taught mainly in the Japanese language, profession-based courses in English, known as Medical English and Dental English, have been integrated into the existing curriculum among its 83 medical and 29 dental schools. Unfortunately, there is neither a core curriculum nor a model syllabus for these courses. This report is based on a survey, two discussion forums, a workshop, and finally, the drafting of a proposed core curriculum for dental English approved by consensus of the participants from each university. The core curriculum covers the theoretical aspects, including dental English terms and oral pathologies; and practical aspects, including blended learning and dentist-patient communication. It is divided into modules and is recommended to be offered for at least two semesters. The core curriculum is expected to guide curriculum developers in schools where dental English courses are yet to be offered or are still in their early development. It may also serve as a model curriculum to medical and dental schools in countries in Asia, Europe, Africa, and Central and South America, where English is not the medium of instruction."},"publication_date":"2014-11-18","publication_name":{"en":"BMC Medical Education","ja":"BMC Medical Education"},"volume":"Vol.14","starting_page":"239","ending_page":"239","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1186/s12909-014-0239-4"],"issn":["1472-6920"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:105, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25040436","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84909955929&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=279095","label":"url"}],"paper_title":{"en":"Systematic review and recommendations for nonodontogenic toothache","ja":"Systematic review and recommendations for nonodontogenic toothache"},"authors":{"en":[{"name":"Yatani H"},{"name":"Komiyama O"},{"name":"Matsuka Yoshizo"},{"name":"Wajima K"},{"name":"Muraoka W"},{"name":"Ikawa M"},{"name":"Sakamoto E"},{"name":"De Laat A"},{"name":"Heir GM"}],"ja":[{"name":"Yatani H"},{"name":"Komiyama O"},{"name":"松香 芳三"},{"name":"Wajima K"},{"name":"Muraoka W"},{"name":"Ikawa M"},{"name":"Sakamoto E"},{"name":"De Laat A"},{"name":"Heir GM"}]},"description":{"en":"Nonodontogenic toothache is a painful condition that occurs in the absence of a clinically evident cause in the teeth or periodontal tissues. The purpose of this review is to improve the accuracy of diagnosis and the quality of dental treatment regarding nonodontogenic toothache. Electronic databases were searched to gather scientific evidence regarding related primary disorders and the management of nonodontogenic toothache. We evaluated the level of available evidence in scientific literature. There are a number of possible causes of nonodontogenic toothache and they should be treated. Nonodontogenic toothache can be categorised into eight groups according to primary disorders as follows: 1) myofascial pain referred to tooth/teeth, 2) neuropathic toothache, 3) idiopathic toothache, 4) neurovascular toothache, 5) sinus pain referred to tooth/teeth, 6) cardiac pain referred to tooth/teeth, 7) psychogenic toothache or toothache of psychosocial origin and 8) toothache caused by various other disorders. We concluded that unnecessary dental treatment should be avoided.","ja":"Nonodontogenic toothache is a painful condition that occurs in the absence of a clinically evident cause in the teeth or periodontal tissues. The purpose of this review is to improve the accuracy of diagnosis and the quality of dental treatment regarding nonodontogenic toothache. Electronic databases were searched to gather scientific evidence regarding related primary disorders and the management of nonodontogenic toothache. We evaluated the level of available evidence in scientific literature. There are a number of possible causes of nonodontogenic toothache and they should be treated. Nonodontogenic toothache can be categorised into eight groups according to primary disorders as follows: 1) myofascial pain referred to tooth/teeth, 2) neuropathic toothache, 3) idiopathic toothache, 4) neurovascular toothache, 5) sinus pain referred to tooth/teeth, 6) cardiac pain referred to tooth/teeth, 7) psychogenic toothache or toothache of psychosocial origin and 8) toothache caused by various other disorders. We concluded that unnecessary dental treatment should be avoided."},"publication_date":"2014-11","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.41","number":"No.11","starting_page":"843","ending_page":"852","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/joor.12208"],"issn":["1365-2842"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:106, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25127373","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84922604353&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=283426","label":"url"}],"paper_title":{"en":"Comparison of platelet serotonin transporter activity in subjects with severe sleep bruxism and control","ja":"Comparison of platelet serotonin transporter activity in subjects with severe sleep bruxism and control"},"authors":{"en":[{"name":"Minakuchi H"},{"name":"Sogawa C"},{"name":"Hara ES"},{"name":"Miki H"},{"name":"Maekawa K"},{"name":"Sogawa N"},{"name":"Kitayama S"},{"name":"Matsuka Yoshizo"},{"name":"Clark GT"},{"name":"Kuboki T"}],"ja":[{"name":"Minakuchi H"},{"name":"Sogawa C"},{"name":"Hara ES"},{"name":"Miki H"},{"name":"Maekawa K"},{"name":"Sogawa N"},{"name":"Kitayama S"},{"name":"松香 芳三"},{"name":"Clark GT"},{"name":"Kuboki T"}]},"description":{"en":"The aim of this study was to evaluate the correlation between sleep bruxism (SB) frequency and serotonin transporter (SERT)-driven serotonin (5-HT)-uptake in platelets. Subjects were dental trainee residents and faculty members of Okayama University Hospital who were aware of having severe or no SB. SB frequency was assessed for 3-consecutive nights by a self-contained electromyographic detector/analyzer, which indicated individual SB levels as one of four grades (score 0, 1, 2 and 3). Subjects were classified as normal control (NC) when SB scores indicated only 0 or 1 during the 3 nights, or as severe SB for scores 2 or 3. Those subjects whose scores fluctuated from 0 to 3 during the 3 nights were omitted from further analysis. Fasting peripheral venous blood samples were collected in the morning following the final SB assessment. Amounts of SERTs proteins collected from peripheral platelets were quantified using ELISA, and SERTs transport activity was assessed by uptake assay using [(3)H]-5-HT. Thirteen severe SB subjects and 7 NC subjects were eligible. Gender distribution, mean age, 5-HT concentration and total amounts of SERT protein in platelets showed no significant differences between NC and severe SB (p=0.85: Chi-squared test; p=0.64, 0.26, 0.46: t-test). However, [(3)H]-5-HT uptake by platelets was significantly greater in NC compared to severe SB subjects (12.79±1.97, 8.27±1.91fmol/10(5) platelets/min, p<0.001, t-test). The results of this pilot study suggest a possible correlation between peripheral platelet serotonin transporter uptake ability and SB severity.","ja":"The aim of this study was to evaluate the correlation between sleep bruxism (SB) frequency and serotonin transporter (SERT)-driven serotonin (5-HT)-uptake in platelets. Subjects were dental trainee residents and faculty members of Okayama University Hospital who were aware of having severe or no SB. SB frequency was assessed for 3-consecutive nights by a self-contained electromyographic detector/analyzer, which indicated individual SB levels as one of four grades (score 0, 1, 2 and 3). Subjects were classified as normal control (NC) when SB scores indicated only 0 or 1 during the 3 nights, or as severe SB for scores 2 or 3. Those subjects whose scores fluctuated from 0 to 3 during the 3 nights were omitted from further analysis. Fasting peripheral venous blood samples were collected in the morning following the final SB assessment. Amounts of SERTs proteins collected from peripheral platelets were quantified using ELISA, and SERTs transport activity was assessed by uptake assay using [(3)H]-5-HT. Thirteen severe SB subjects and 7 NC subjects were eligible. Gender distribution, mean age, 5-HT concentration and total amounts of SERT protein in platelets showed no significant differences between NC and severe SB (p=0.85: Chi-squared test; p=0.64, 0.26, 0.46: t-test). However, [(3)H]-5-HT uptake by platelets was significantly greater in NC compared to severe SB subjects (12.79±1.97, 8.27±1.91fmol/10(5) platelets/min, p<0.001, t-test). The results of this pilot study suggest a possible correlation between peripheral platelet serotonin transporter uptake ability and SB severity."},"publication_date":"2014-10","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.58","number":"No.4","starting_page":"217","ending_page":"222","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2014.06.003"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:107, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25051899","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84906046664&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=279096","label":"url"}],"paper_title":{"en":"Effect of an exclusion range of jaw movement data from the intercuspal position on the estimation of the kinematic axis point","ja":"Effect of an exclusion range of jaw movement data from the intercuspal position on the estimation of the kinematic axis point"},"authors":{"en":[{"name":"Shigemoto Shuji"},{"name":"Bando N"},{"name":"Nishigawa Keisuke"},{"name":"Tajima Toyoko"},{"name":"Okura Kazuo"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"重本 修伺"},{"name":"Bando N"},{"name":"西川 啓介"},{"name":"田島 登誉子"},{"name":"大倉 一夫"},{"name":"松香 芳三"}]},"description":{"en":"In patients who have lost natural occlusal contacts, the centric relation is usually estimated based on several anatomical factors such as the temporomandibular joint and masticatory muscles except dental arch. The clinical procedure to record the centric relation often depends on the clinician's expertise and technique; an objective method to determine proper occlusal position is desirable. The kinematic axis point (KAP) is kinematically estimated from sagittal movements and is an ideal posterior reference point that is used in dental articulators for reproducing jaw movement. Occlusal registration using the KAP may serve as a definite objective technique. The aim of this study is to investigate the effect of the exclusion range of sagittal jaw movement data from the intercuspal position (ICP) on the estimation of the KAP. The complete and incomplete sagittal border movement data of dentate subjects were used to estimate the KAPs. The locations of the estimated KAPs were compared. The results indicate that the incomplete sagittal border jaw movement data set does not include data points inside a 7mm distance from the ICP can be used for estimation of the KAP. In conclusion, the sagittal border jaw movement data around the ICP is not indispensable in the valid identification of the KAP.","ja":"In patients who have lost natural occlusal contacts, the centric relation is usually estimated based on several anatomical factors such as the temporomandibular joint and masticatory muscles except dental arch. The clinical procedure to record the centric relation often depends on the clinician's expertise and technique; an objective method to determine proper occlusal position is desirable. The kinematic axis point (KAP) is kinematically estimated from sagittal movements and is an ideal posterior reference point that is used in dental articulators for reproducing jaw movement. Occlusal registration using the KAP may serve as a definite objective technique. The aim of this study is to investigate the effect of the exclusion range of sagittal jaw movement data from the intercuspal position (ICP) on the estimation of the KAP. The complete and incomplete sagittal border movement data of dentate subjects were used to estimate the KAPs. The locations of the estimated KAPs were compared. The results indicate that the incomplete sagittal border jaw movement data set does not include data points inside a 7mm distance from the ICP can be used for estimation of the KAP. In conclusion, the sagittal border jaw movement data around the ICP is not indispensable in the valid identification of the KAP."},"publication_date":"2014-09","publication_name":{"en":"Medical Engineering & Physics","ja":"Medical Engineering & Physics"},"volume":"Vol.36","number":"No.9","starting_page":"1162","ending_page":"1167","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.medengphy.2014.06.013"],"issn":["1873-4030"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:108, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/130004953503/","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111991","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/24951163","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001205300317952/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84904513125&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=278843","label":"url"}],"paper_title":{"en":"Case report of recurrent temporomandibular joint open lock associated with abrupt reduction of displaced articular disk","ja":"Case report of recurrent temporomandibular joint open lock associated with abrupt reduction of displaced articular disk"},"authors":{"en":[{"name":"Nishigawa Keisuke"},{"name":"Nakano Masanori"},{"name":"Ishikawa Teruaki"},{"name":"Bando Eiichi"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"西川 啓介"},{"name":"中野 雅德"},{"name":"石川 輝明"},{"name":"坂東 永一"},{"name":"松香 芳三"}]},"description":{"en":"This report describes the case of a 51-year-old male patient who initially presented at age 23 with a habitual intermittent open lock (at >35mm) in the left temporomandibular joint (TMJ). The patient was able to manage this affliction through rapid-repetition jaw opening and closing. Tomography of the joint showed no irregular morphology, but intraoral examination revealed an occlusal interference at the mandibular left third molar during leftwards excursion. For this patient, alteration of lateral guidance using a palatal plate attached to the maxillary left canine precluded this intermittent open lock, but at 22 years of age, the open lock recurred and could not be relieved by the patient, who was unable to assume an occlusal position. Because conservative treatment was ineffective, a pumping manipulation technique was applied to reduce the open lock, after which the patient has maintained good jaw function. MRI taken before and after repositioning indicated that abrupt reduction of a displaced articular disk was the cause of the open lock, and that this articular disk was restored to its proper position during the manipulation. Most TMJ open locks occur as anterior dislocation, where the mandibular head becomes trapped anterior to the articular eminences, causing excessive opening and difficulty closing. Our clinical findings from this patient indicate that open lock can occur through abrupt reduction of a displaced articular disk, particularly in patients with chronic internal derangement of the TMJ. TMJ open lock can occur following abrupt reduction of a displaced articular disk.","ja":"This report describes the case of a 51-year-old male patient who initially presented at age 23 with a habitual intermittent open lock (at >35mm) in the left temporomandibular joint (TMJ). The patient was able to manage this affliction through rapid-repetition jaw opening and closing. Tomography of the joint showed no irregular morphology, but intraoral examination revealed an occlusal interference at the mandibular left third molar during leftwards excursion. For this patient, alteration of lateral guidance using a palatal plate attached to the maxillary left canine precluded this intermittent open lock, but at 22 years of age, the open lock recurred and could not be relieved by the patient, who was unable to assume an occlusal position. Because conservative treatment was ineffective, a pumping manipulation technique was applied to reduce the open lock, after which the patient has maintained good jaw function. MRI taken before and after repositioning indicated that abrupt reduction of a displaced articular disk was the cause of the open lock, and that this articular disk was restored to its proper position during the manipulation. Most TMJ open locks occur as anterior dislocation, where the mandibular head becomes trapped anterior to the articular eminences, causing excessive opening and difficulty closing. Our clinical findings from this patient indicate that open lock can occur through abrupt reduction of a displaced articular disk, particularly in patients with chronic internal derangement of the TMJ. TMJ open lock can occur following abrupt reduction of a displaced articular disk."},"publication_date":"2014-07","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.58","number":"No.3","starting_page":"184","ending_page":"190","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2014.04.001"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:109, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/130004953491/","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/110150","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/24746524","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001205300123776/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84899622693&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=277619","label":"url"}],"paper_title":{"en":"Clinical application of removable partial dentures using thermoplastic resin Part II: Material properties and clinical features of non-metal clasp dentures","ja":"Clinical application of removable partial dentures using thermoplastic resin Part II: Material properties and clinical features of non-metal clasp dentures"},"authors":{"en":[{"name":"Fueki K"},{"name":"Ohkubo C"},{"name":"Yatabe M"},{"name":"Arakawa I"},{"name":"Arita M"},{"name":"Ino S"},{"name":"Kanamori T"},{"name":"Kawai Y"},{"name":"Kawara M"},{"name":"Komiyama O"},{"name":"Suzuki T"},{"name":"Nagata K"},{"name":"Hosoki Maki"},{"name":"Masumi S"},{"name":"Yamauchi M"},{"name":"Aita H"},{"name":"Ono T"},{"name":"Kondo H"},{"name":"Tamaki K"},{"name":"Matsuka Yoshizo"},{"name":"Tsukasaki H"},{"name":"Fujisawa M"},{"name":"Baba K"},{"name":"Koyano K"},{"name":"Yatani H"}],"ja":[{"name":"Fueki K"},{"name":"Ohkubo C"},{"name":"Yatabe M"},{"name":"Arakawa I"},{"name":"Arita M"},{"name":"Ino S"},{"name":"Kanamori T"},{"name":"Kawai Y"},{"name":"Kawara M"},{"name":"Komiyama O"},{"name":"Suzuki T"},{"name":"Nagata K"},{"name":"細木 眞紀"},{"name":"Masumi S"},{"name":"Yamauchi M"},{"name":"Aita H"},{"name":"Ono T"},{"name":"Kondo H"},{"name":"Tamaki K"},{"name":"松香 芳三"},{"name":"Tsukasaki H"},{"name":"Fujisawa M"},{"name":"Baba K"},{"name":"Koyano K"},{"name":"Yatani H"}]},"description":{"en":"This position paper reviews physical and mechanical properties of thermoplastic resin used for non-metal clasp dentures, and describes feature of each thermoplastic resin in clinical application of non-metal clasp dentures and complications based on clinical experience of expert panels. Since products of thermoplastic resin have great variability in physical and mechanical properties, clinicians should utilize them with careful consideration of the specific properties of each product. In general, thermoplastic resin has lower color-stability and higher risk for fracture than polymethyl methacrylate. Additionally, the surface of thermoplastic resin becomes roughened more easily than polymethyl methacrylate. Studies related to material properties of thermoplastic resin, treatment efficacy and follow-up are insufficient to provide definitive conclusions at this time. Therefore, this position paper should be revised based on future studies and a clinical guideline should be provided.","ja":"This position paper reviews physical and mechanical properties of thermoplastic resin used for non-metal clasp dentures, and describes feature of each thermoplastic resin in clinical application of non-metal clasp dentures and complications based on clinical experience of expert panels. Since products of thermoplastic resin have great variability in physical and mechanical properties, clinicians should utilize them with careful consideration of the specific properties of each product. In general, thermoplastic resin has lower color-stability and higher risk for fracture than polymethyl methacrylate. Additionally, the surface of thermoplastic resin becomes roughened more easily than polymethyl methacrylate. Studies related to material properties of thermoplastic resin, treatment efficacy and follow-up are insufficient to provide definitive conclusions at this time. Therefore, this position paper should be revised based on future studies and a clinical guideline should be provided."},"publication_date":"2014-04-18","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.58","number":"No.2","starting_page":"71","ending_page":"84","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2014.03.002"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:110, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/130004953481/","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/24461323","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282680276079232/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84892985157&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=275418","label":"url"}],"paper_title":{"en":"Clinical application of removable partial dentures using thermoplastic resin-Part I: Definition and indication of non-metal clasp dentures","ja":"Clinical application of removable partial dentures using thermoplastic resin-Part I: Definition and indication of non-metal clasp dentures"},"authors":{"en":[{"name":"Fueki K"},{"name":"Ohkubo C"},{"name":"Yatabe M"},{"name":"Arakawa I"},{"name":"Arita M"},{"name":"Ino S"},{"name":"Kanamori T"},{"name":"Kawai Y"},{"name":"Kawara M"},{"name":"Komiyama O"},{"name":"Suzuki T"},{"name":"Nagata K"},{"name":"Hosoki Maki"},{"name":"Masumi S"},{"name":"Yamauchi M"},{"name":"Aita H"},{"name":"Ono T"},{"name":"Kondo H"},{"name":"Tamaki K"},{"name":"Matsuka Yoshizo"},{"name":"Tsukasaki H"},{"name":"Fujisawa M"},{"name":"Baba K"},{"name":"Koyano K"},{"name":"Yatani H"}],"ja":[{"name":"Fueki K"},{"name":"Ohkubo C"},{"name":"Yatabe M"},{"name":"Arakawa I"},{"name":"Arita M"},{"name":"Ino S"},{"name":"Kanamori T"},{"name":"Kawai Y"},{"name":"Kawara M"},{"name":"Komiyama O"},{"name":"Suzuki T"},{"name":"Nagata K"},{"name":"細木 眞紀"},{"name":"Masumi S"},{"name":"Yamauchi M"},{"name":"Aita H"},{"name":"Ono T"},{"name":"Kondo H"},{"name":"Tamaki K"},{"name":"松香 芳三"},{"name":"Tsukasaki H"},{"name":"Fujisawa M"},{"name":"Baba K"},{"name":"Koyano K"},{"name":"Yatani H"}]},"description":{"en":"This position paper proposes a definition and naming standard for removable partial dentures (RPDs) using thermoplastic resin, and presents a guideline for clinical application. A panel of 14 experts having broad experience with clinical application of RPDs using thermoplastic resin was selected from members of the Japan Prosthodontic Society. At a meeting of the panel, \"non-metal clasp denture\" was referred as the generic name of RPDs with retentive elements (resin clasps) made of thermoplastic resin. The panel classified non-metal clasp dentures into two types: one with a flexible structure that lacks a metal framework and the other having a rigid structure that includes a metal framework. According to current prosthetic principles, flexible non-metal clasp dentures are not recommended as definitive dentures, except for limited cases such as patients with a metal allergy. Rigid non-metal clasp dentures are recommended in cases where patients will not accept metal clasps for esthetic reasons. Non-metal clasp dentures should follow the same design principles as conventional RPDs using metal clasps.","ja":"This position paper proposes a definition and naming standard for removable partial dentures (RPDs) using thermoplastic resin, and presents a guideline for clinical application. A panel of 14 experts having broad experience with clinical application of RPDs using thermoplastic resin was selected from members of the Japan Prosthodontic Society. At a meeting of the panel, \"non-metal clasp denture\" was referred as the generic name of RPDs with retentive elements (resin clasps) made of thermoplastic resin. The panel classified non-metal clasp dentures into two types: one with a flexible structure that lacks a metal framework and the other having a rigid structure that includes a metal framework. According to current prosthetic principles, flexible non-metal clasp dentures are not recommended as definitive dentures, except for limited cases such as patients with a metal allergy. Rigid non-metal clasp dentures are recommended in cases where patients will not accept metal clasps for esthetic reasons. Non-metal clasp dentures should follow the same design principles as conventional RPDs using metal clasps."},"publication_date":"2014-01-22","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.58","number":"No.1","starting_page":"3","ending_page":"10","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2013.12.002"],"issn":["1883-1958"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:111, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/40019971949/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520010381212751872/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=278893","label":"url"}],"paper_title":{"en":"Potential Risk of Metal Allergy Associated with Pierced Earrings Containing Nickel","ja":"ニッケル含有ピアスによる金属アレルギー発症の危険性について"},"authors":{"en":[{"name":"Hosoki Maki"},{"name":"Tajima Toyoko"},{"name":"Nishigawa Keisuke"},{"name":"Takeuchi Hisahiro"},{"name":"Matsuka Yoshizo"},{"name":"Kubo Yoshiaki"}],"ja":[{"name":"細木 眞紀"},{"name":"田島 登誉子"},{"name":"西川 啓介"},{"name":"竹内 久裕"},{"name":"松香 芳三"},{"name":"久保 宜明"}]},"publication_date":"2014-01","publication_name":{"en":"Journal of Environmental Dermatology and Cutaneous Allergology","ja":"日本皮膚アレルギー・接触皮膚炎学会雑誌"},"volume":"Vol.8","number":"No.1","starting_page":"12","ending_page":"20","languages":["jpn"],"referee":true,"identifiers":{"issn":["1882-0123"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:112, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/40020028373/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520009408421277696/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=280935","label":"url"}],"paper_title":{"en":"Mandibular Movement during Sleep Bruxism: Mandibular Position with Peak Masseter Muscle Activity","ja":"Mandibular Movement during Sleep Bruxism: Mandibular Position with Peak Masseter Muscle Activity"},"authors":{"en":[{"name":"Suzuki Yoshitaka"},{"name":"Okura Kazuo"},{"name":"Shigemoto Shuji"},{"name":"Tajima Toyoko"},{"name":"Rodis Omar"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"鈴木 善貴"},{"name":"大倉 一夫"},{"name":"重本 修伺"},{"name":"田島 登誉子"},{"name":"ロディス オマー"},{"name":"松香 芳三"}]},"publication_date":"2013-12","publication_name":{"en":"The Journal of Japan Association of Oral Rehabilitation","ja":"The Journal of Japan Association of Oral Rehabilitation"},"volume":"Vol.26","number":"No.1","starting_page":"35","ending_page":"42","languages":["eng"],"referee":true,"identifiers":{"issn":["2186-2052"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:113, {"insert":{"user_id":"B000340651","type":"published_papers","id":"39296854"},"force":{"see_also":[{"@id":"http://id.ndl.go.jp/bib/025013698","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1522262179658153344/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=272831","label":"url"}],"paper_title":{"en":"義歯管理に関する臨床的エビデンス","ja":"義歯管理に関する臨床的エビデンス"},"authors":{"en":[{"name":"馬場 一美"},{"name":"塚崎 弘明"},{"name":"笛木 賢治"},{"name":"村田 比呂司"},{"name":"尾澤 昌悟"},{"name":"Matsuka Yoshizo"},{"name":"小野 高裕"},{"name":"會田 英紀"},{"name":"近藤 尚知"},{"name":"玉置 勝司"},{"name":"藤澤 政紀"},{"name":"矢谷 博文"},{"name":"古谷野 潔"}],"ja":[{"name":"馬場 一美"},{"name":"塚崎 弘明"},{"name":"笛木 賢治"},{"name":"村田 比呂司"},{"name":"尾澤 昌悟"},{"name":"松香 芳三"},{"name":"小野 高裕"},{"name":"會田 英紀"},{"name":"近藤 尚知"},{"name":"玉置 勝司"},{"name":"藤澤 政紀"},{"name":"矢谷 博文"},{"name":"古谷野 潔"}]},"publication_date":"2013-11","publication_name":{"en":"The Journal of the Japan Dental Association","ja":"日本歯科医師会雑誌"},"volume":"Vol.66","number":"No.8","starting_page":"763","ending_page":"773","languages":["jpn"],"referee":true,"identifiers":{"issn":["0047-1763"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:114, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/24126107","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84886444978&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=272748","label":"url"}],"paper_title":{"en":"Retrospective investigation of the remaining teeth status of patients with implant-supported fixed partial dentures in unilateral free-end edentulism","ja":"Retrospective investigation of the remaining teeth status of patients with implant-supported fixed partial dentures in unilateral free-end edentulism"},"authors":{"en":[{"name":"Yamazaki Seiya"},{"name":"Arakawa Hikaru"},{"name":"Maekawa kenji"},{"name":"Hara S Emilio"},{"name":"Noda Kinji"},{"name":"Minakuchi Hajime"},{"name":"Sonoyama Wataru"},{"name":"Matsuka Yoshizo"},{"name":"Kuboki Takuo"}],"ja":[{"name":"Yamazaki Seiya"},{"name":"Arakawa Hikaru"},{"name":"Maekawa kenji"},{"name":"Hara S Emilio"},{"name":"Noda Kinji"},{"name":"Minakuchi Hajime"},{"name":"Sonoyama Wataru"},{"name":"松香 芳三"},{"name":"Kuboki Takuo"}]},"description":{"en":"This study aimed to compare the various complication-free rates and survival rates of remaining teeth among implant-supported fixed dentures (IFDs), removable partial dentures (RPDs) and no-restoration (NR) patients with unilateral free-end edentulism. The study subjects were selected among those who received prosthodontic treatment at Okayama University Dental Hospital for their unilateral free-end edentulism (2 or 3 missing teeth). Thirty-three patients were included in the IFD group, 41 matched patients in the RPD group, and 10 patients who received RPDs but refused their use were regarded as NR group. The remaining dentition was classified into five subcategories in relation to the missing portion: adjacent teeth to the missing portion (AD), contralateral posterior dentition in the same jaw (CS) and in the opposite jaw (CO), ipsilateral opposing posterior dentition (IO), and anterior dentition (AN). Complications were defined as tooth extraction, periodontal lesions, periapical lesions or loss of retention of the prosthesis and were assessed by one examiner based on the hospital chart records. The cumulative complication-free rates in the remaining teeth were significantly different among each of the three groups (p<0.01), with a significantly lower incidence rate in the IFD group. Regarding the cumulative survival rate of the remaining teeth, there was a significant difference only between IFD and NR group (p=0.01), especially in the CO region (p=0.04). Stable posterior occlusal support obtained with IFD treatment for unilateral free-end edentulism may reduce the incidence of complications in the remaining teeth, by decreasing the adverse mechanical stress.","ja":"This study aimed to compare the various complication-free rates and survival rates of remaining teeth among implant-supported fixed dentures (IFDs), removable partial dentures (RPDs) and no-restoration (NR) patients with unilateral free-end edentulism. The study subjects were selected among those who received prosthodontic treatment at Okayama University Dental Hospital for their unilateral free-end edentulism (2 or 3 missing teeth). Thirty-three patients were included in the IFD group, 41 matched patients in the RPD group, and 10 patients who received RPDs but refused their use were regarded as NR group. The remaining dentition was classified into five subcategories in relation to the missing portion: adjacent teeth to the missing portion (AD), contralateral posterior dentition in the same jaw (CS) and in the opposite jaw (CO), ipsilateral opposing posterior dentition (IO), and anterior dentition (AN). Complications were defined as tooth extraction, periodontal lesions, periapical lesions or loss of retention of the prosthesis and were assessed by one examiner based on the hospital chart records. The cumulative complication-free rates in the remaining teeth were significantly different among each of the three groups (p<0.01), with a significantly lower incidence rate in the IFD group. Regarding the cumulative survival rate of the remaining teeth, there was a significant difference only between IFD and NR group (p=0.01), especially in the CO region (p=0.04). Stable posterior occlusal support obtained with IFD treatment for unilateral free-end edentulism may reduce the incidence of complications in the remaining teeth, by decreasing the adverse mechanical stress."},"publication_date":"2013-10-11","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.57","number":"No.4","starting_page":"262","ending_page":"267","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2013.08.001"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:115, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=272654","label":"url"}],"paper_title":{"en":"熱可塑性樹脂を用いた部分床義歯 (ノンメタルクラスプデンチャー)の臨床応用","ja":"熱可塑性樹脂を用いた部分床義歯 (ノンメタルクラスプデンチャー)の臨床応用"},"authors":{"en":[{"name":"笛木 賢治"},{"name":"大久保 力廣"},{"name":"谷田部 優"},{"name":"荒川 一郎"},{"name":"有田 正博"},{"name":"井野 智"},{"name":"金森 敏和"},{"name":"河相 安彦"},{"name":"川良 美佐雄"},{"name":"小見山 道"},{"name":"鈴木 哲也"},{"name":"永田 和裕"},{"name":"細木 真紀"},{"name":"鱒見 進一"},{"name":"山内 六男"},{"name":"會田 英紀"},{"name":"小野 高裕"},{"name":"近藤 尚知"},{"name":"玉置 勝司"},{"name":"Matsuka Yoshizo"},{"name":"塚崎 弘明"},{"name":"藤澤 政紀"},{"name":"馬場 一美"},{"name":"古谷野 潔"}],"ja":[{"name":"笛木 賢治"},{"name":"大久保 力廣"},{"name":"谷田部 優"},{"name":"荒川 一郎"},{"name":"有田 正博"},{"name":"井野 智"},{"name":"金森 敏和"},{"name":"河相 安彦"},{"name":"川良 美佐雄"},{"name":"小見山 道"},{"name":"鈴木 哲也"},{"name":"永田 和裕"},{"name":"細木 真紀"},{"name":"鱒見 進一"},{"name":"山内 六男"},{"name":"會田 英紀"},{"name":"小野 高裕"},{"name":"近藤 尚知"},{"name":"玉置 勝司"},{"name":"松香 芳三"},{"name":"塚崎 弘明"},{"name":"藤澤 政紀"},{"name":"馬場 一美"},{"name":"古谷野 潔"}]},"publication_date":"2013-10","publication_name":{"en":"Annals of Japan Prosthodontic Society","ja":"日本補綴歯科学会誌"},"volume":"Vol.5","number":"No.4","starting_page":"387","ending_page":"408","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.2186/ajps.5.387"],"issn":["1883-6860"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:116, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=272653","label":"url"}],"paper_title":{"en":"Occlusal discomfort syndrome","ja":"咬合違和感症候群"},"authors":{"en":[{"name":"玉置 勝司"},{"name":"石垣 尚一"},{"name":"小川 匠"},{"name":"尾口 仁志"},{"name":"加藤 隆史"},{"name":"菅沼 岳史"},{"name":"島田 淳"},{"name":"貞森 紳丞"},{"name":"築山 能大"},{"name":"西川 洋二"},{"name":"鱒見 進一"},{"name":"山口 泰彦"},{"name":"會田 英紀"},{"name":"小野 高裕"},{"name":"近藤 尚知"},{"name":"塚崎 弘明"},{"name":"笛木 賢治"},{"name":"藤澤 政紀"},{"name":"Matsuka Yoshizo"},{"name":"馬場 一美"},{"name":"古谷野 潔"}],"ja":[{"name":"玉置 勝司"},{"name":"石垣 尚一"},{"name":"小川 匠"},{"name":"尾口 仁志"},{"name":"加藤 隆史"},{"name":"菅沼 岳史"},{"name":"島田 淳"},{"name":"貞森 紳丞"},{"name":"築山 能大"},{"name":"西川 洋二"},{"name":"鱒見 進一"},{"name":"山口 泰彦"},{"name":"會田 英紀"},{"name":"小野 高裕"},{"name":"近藤 尚知"},{"name":"塚崎 弘明"},{"name":"笛木 賢治"},{"name":"藤澤 政紀"},{"name":"松香 芳三"},{"name":"馬場 一美"},{"name":"古谷野 潔"}]},"description":{"en":"One of the patients with difficulty, there is a case to complain of discomfort or abnormal sense of occlusion, the dentist is able to encounter patients with objective findings that can not be confirmed. Usually, although confirmation is using articulating paper, wax, and silicone materials, no abnormalities found in the state especially occlusal contact. In addition, for the insistent demand of the patient to the discomfort occlusion, the dentist may easily gone the occlusal adjustment. As a result, not only does not improve the patient's complaint, its symptoms may even also be worse in reverse. And the relationship of trust between the patient and the dentist will break. And it may even be caught in a direction unfavorable unexpected. For discomfort related to occlusion, in clinical practice guidelines committee in Japan Prostjodontic Siciety, creating clinical practice guidelines related to occlusal dysesthesia were studied.In the development of clinical practice guidelines, we have attempted to formulate guidelines created by a panel of the Commission, there are few high-quality paper sufficiently related to occlusal dysesthesia, did not lead to the creation of clinical practice guidelines. Therefore, a consensus meeting held on occlusal discomfort as Japan Prosthodontic Society, examined the appropriate designation of this disease. From the results of the pre-survey, this disease has to be called and \"occlusal discomfort syndrome\".For the purpose of indicating the direction of research activities and creating clinical practice guidelines in the future, the position paper of this time, a multi-center was carried out on the current situation and the course of dental treatment up to this syndrome patients uncomfortable occlusion literature and one of the few in the past was created from the findings of a patient with.","ja":"難症例の1つに咬み合わせ異常感や違和感があり,その訴えに対応する客観的所見が確認できない症例に遭遇することがある.通常,咬合紙,ワックス,シリコーンなどを用いて確認はするものの,咬合接触状態に特に異常は見つからない.さらに,患者の咬合に関する執拗な訴えに対して歯科医師が患者に問題の部位を確認してもらい,患者の指示により咬合調整を行ってしまうといった患者の感覚主導型治療に陥ってしまうことがある.その結果,患者の訴えは改善しないばかりか,逆に悪化することもさえもある.そして,患者と歯科医師の信頼関係が壊れ,思わぬ方向に陥ってしまうことも珍しくない. このような患者が訴える咬合に関する違和感に対して,社団法人日本補綴歯科学会,診療ガイドライン委員会において,平成23年度「咬合感覚異常(症)」に関する診療ガイドラインの策定が検討された.診療ガイドラインの策定に際し,委員会の作成パネルによるガイドライン策定を試みたが,咬合感覚異常(症)に関する十分に質の高い論文は少なく,診療ガイドラインの作成には至らなかった.そこで,本委員会のパネルで協議した結果,「咬合感覚異常(症)」に対する日本補綴歯科学会としてのコンセンサス・ミーティングを開催して本疾患の適切な呼称の検討を行った.また事前のアンケート調査結果から,このような病態を「咬合違和感症候群(occlusal discomfort syndrome)」とした. 今回のポジションペーパーは,今後の診療ガイドラインの作成とそれに対する研究活動の方向性を示す目的で,過去の文献と咬合違和感症候群患者のこれまでの歯科治療の経過や現在の状況について実施した多施設による患者の調査結果をもとに作成された."},"publication_date":"2013-10","publication_name":{"en":"Annals of Japan Prosthodontic Society","ja":"日本補綴歯科学会誌"},"volume":"Vol.5","number":"No.4","starting_page":"369","ending_page":"386","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.2186/ajps.5.369"],"issn":["1883-4426"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:117, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84881556684&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=267311","label":"url"}],"paper_title":{"en":"Primary treatment of temporomandibular disorders: The Japanese Society for the temporomandibular joint evidence-based clinical practice guidelines, 2nd edition","ja":"Primary treatment of temporomandibular disorders: The Japanese Society for the temporomandibular joint evidence-based clinical practice guidelines, 2nd edition"},"authors":{"en":[{"name":"Yuasa H"},{"name":"Kino K"},{"name":"Kubota E"},{"name":"Kakudo K"},{"name":"Sugisaki M"},{"name":"Nishiyama A"},{"name":"Matsuka Yoshizo"},{"name":"Ogi N"},{"name":"the Evidence-based Clinical Practice Guidelines Task Force"}],"ja":[{"name":"Yuasa H"},{"name":"Kino K"},{"name":"Kubota E"},{"name":"Kakudo K"},{"name":"Sugisaki M"},{"name":"Nishiyama A"},{"name":"松香 芳三"},{"name":"Ogi N"},{"name":"the Evidence-based Clinical Practice Guidelines Task Force"}]},"publication_date":"2013-08","publication_name":{"en":"Japanese Dental Science Review","ja":"Japanese Dental Science Review"},"volume":"Vol.49","number":"No.3","starting_page":"89","ending_page":"98","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jdsr.2013.05.002"],"issn":["1882-7616"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:118, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://search.jamas.or.jp/link/ui/2014188971","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001205301084416/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264937","label":"url"}],"paper_title":{"en":"Reliability and validity of diagnostic nomenclature system of prosthetic dentistry","ja":"補綴歯科治療病名システムの信頼性と妥当性の検討"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"萩原 芳幸"},{"name":"玉置 勝司"},{"name":"Takeuchi Hisahiro"},{"name":"藤澤 政紀"},{"name":"小野 高裕"},{"name":"築山 能大"},{"name":"Nagao Kan"},{"name":"津賀 一弘"},{"name":"會田 英紀"},{"name":"近藤 尚知"},{"name":"笛木 賢治"},{"name":"塚崎 弘明"},{"name":"石橋 寛二"},{"name":"藤井 重壽"},{"name":"平井 敏博"},{"name":"佐々木 啓一"},{"name":"矢谷 博文"},{"name":"五十嵐 順正"},{"name":"Sato Yuji"},{"name":"Ichikawa Tetsuo"},{"name":"松村 英雄"},{"name":"山森 徹雄"},{"name":"窪木 拓男"},{"name":"馬場 一美"},{"name":"古谷野 潔"}],"ja":[{"name":"松香 芳三"},{"name":"萩原 芳幸"},{"name":"玉置 勝司"},{"name":"竹内 久裕"},{"name":"藤澤 政紀"},{"name":"小野 高裕"},{"name":"築山 能大"},{"name":"永尾 寛"},{"name":"津賀 一弘"},{"name":"會田 英紀"},{"name":"近藤 尚知"},{"name":"笛木 賢治"},{"name":"塚崎 弘明"},{"name":"石橋 寛二"},{"name":"藤井 重壽"},{"name":"平井 敏博"},{"name":"佐々木 啓一"},{"name":"矢谷 博文"},{"name":"五十嵐 順正"},{"name":"佐藤 裕二"},{"name":"市川 哲雄"},{"name":"松村 英雄"},{"name":"山森 徹雄"},{"name":"窪木 拓男"},{"name":"馬場 一美"},{"name":"古谷野 潔"}]},"description":{"en":"Purpose: The Japan Prosthodontic Society (a public interest incorporated association) proposed a new diagnostic nomenclature system method that is based on pathogenesis and etiology for providing adequate prosthodontic treatment to patients. This diagnostic nomenclature system is based on \"factor\" and \"disability\", and assumes that a disability is caused by a factor. The aim of this study was to analyze the reliability and validity of several dentists' diagnoses on mock patient charts.Methods: The Clinical Guideline Committee of the Japan Prosthodontic Society made mock patient charts and decided the disease name with the new diagnosis system. Fifty evaluators (prosthodontic specialists and hospital residents) answered the disease name with the new diagnosis system. The reliability and validity of the diagnoses were analyzed.Results: Krippendorff's α, which evaluates the reliability, was 0.378 (prosthodontic specialists) and 0.401 (hospital residents). The value was 0.524 with the top 10 evaluators, and 0.628 with the top 2 evaluators. There was no difference between the prosthodontic specialists and hospital residents in the correct answer rate. The correct answer rate for common dental diseases was high and that for uncommon dental diseases was low. Moreover, there was no relation between the correct answer rate and answering time or years of experience.Conclusion: The reliability of the answers among all evaluators was not high, but it was high among the evaluators who showed a high correct answer rate in this study. The correct answer rate for common dental diseases was high and that for uncommon dental diseases was low.","ja":"目的:(社)日本補綴歯科学会は病態とその発現機序の把握に基づく適切な補綴歯科治療を国民に提供するために,補綴歯科治療における新たな病名システムを提案した.これは患者に生じている「障害」を病名の基本とし,この障害を引き起こしている「要因」を併記して病名システムとするものであり,「A(要因)によるB(障害)」を病名システムの基本的な表現法としている.本研究の目的は考案した方法に従って決定した補綴歯科治療における病名の信頼性と妥当性を検討することである.方法:模擬患者カルテを作成し,(社)日本補綴歯科学会診療ガイドライン委員会で模範解答としての病名(以下,模範病名)を決定した.その後,合計50 名の評価者(日本補綴歯科学会専門医(以下,補綴歯科専門医)ならびに大学病院研修歯科医(以下,研修医))に診断をしてもらい,評価者間における病名の一致度(信頼性)ならびに(社)日本補綴歯科学会診療ガイドライン委員会による模範病名との一致度(妥当性)を検討した.結果:評価者間の一致度を検討するための算出したKrippendorff's αは全体では0.378,補綴歯科専門医では0.370,研修医では0.401 であった.Krippendorff's αは模範病名との一致度の高い上位10 名の評価者(補綴歯科専門医:3 名,研修医:7 名)では0.524,上位2 名の評価者(補綴歯科専門医:1 名,研修医:1 名)では0.648 と上昇した.日常的に頻繁に遭遇する病名に関しては模範病名との一致度が高かったが,日常的に遭遇しない病名は模範病名との一致度は低い状況であった.さらに,模範病名との一致度とアンケート回答時間や診療経験年数の関連性を検討したところ,相関関係はみられなかった.結論:全評価者間の一致度を指標とした本病名システムの信頼性は高くはなかったが,模範病名との一致度の高い評価者間では一致度が高かった.日常的に遭遇する補綴関連病名については模範病名との一致度が高かった.以上から(公社)日本補綴歯科学会の新しい病名システムは臨床上十分な信頼性と妥当性を有することが示唆された."},"publication_date":"2013-07-09","publication_name":{"en":"Annals of Japan Prosthodontic Society","ja":"日本補綴歯科学会誌"},"volume":"Vol.5","number":"No.3","starting_page":"281","ending_page":"290","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.2186/ajps.5.281"],"issn":["1883-4426"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:119, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23838063","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84880955650&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264496","label":"url"}],"paper_title":{"en":"A retrospective comparative ten-year study of cumulative survival rates of remaining teeth in large edentulism treated with implant-supported fixed partial dentures or removable partial dentures","ja":"A retrospective comparative ten-year study of cumulative survival rates of remaining teeth in large edentulism treated with implant-supported fixed partial dentures or removable partial dentures"},"authors":{"en":[{"name":"Yamazaki Seiya"},{"name":"Arakawa Hikaru"},{"name":"Maekawa kenji"},{"name":"Hara S Emilio"},{"name":"Noda Kinji"},{"name":"Minakuchi Hajime"},{"name":"Sonoyama Wataru"},{"name":"Matsuka Yoshizo"},{"name":"Kuboki Takuo"}],"ja":[{"name":"Yamazaki Seiya"},{"name":"Arakawa Hikaru"},{"name":"Maekawa kenji"},{"name":"Hara S Emilio"},{"name":"Noda Kinji"},{"name":"Minakuchi Hajime"},{"name":"Sonoyama Wataru"},{"name":"松香 芳三"},{"name":"Kuboki Takuo"}]},"description":{"en":"This study aimed to compare the survival rates of remaining teeth between implant-supported fixed dentures (IFDs) and removable partial dentures (RPDs) in patients with large edentulous cases. The second goal was to assess the risk factors for remaining tooth loss. The study subjects were selected among those who received prosthodontic treatment at Okayama University Dental Hospital for their edentulous space exceeding at least four continuous missing teeth. Twenty-one patients were included in the IFD group and 82 patients were included in the RPD group. Survival rates of remaining teeth were calculated in three subcategories: (1) whole remaining teeth, (2) adjacent teeth to intended edentulous space, and (3) opposing teeth to intended edentulous space. The ten-year cumulative survival rate of the whole remaining teeth was significantly higher in the IFD group (40.0%) than in the RPD group (24.4%). On the other hand, there was no significant difference between two groups in the survival rate of teeth adjacent or opposing to intended edentulous space. A Cox proportional hazard analysis revealed that RPD restoration and gender (male) were the significant risk factors for remaining tooth loss (whole remaining teeth). These results suggest that IFD treatment can reduce the incidence of remaining tooth loss in large edentulous cases.","ja":"This study aimed to compare the survival rates of remaining teeth between implant-supported fixed dentures (IFDs) and removable partial dentures (RPDs) in patients with large edentulous cases. The second goal was to assess the risk factors for remaining tooth loss. The study subjects were selected among those who received prosthodontic treatment at Okayama University Dental Hospital for their edentulous space exceeding at least four continuous missing teeth. Twenty-one patients were included in the IFD group and 82 patients were included in the RPD group. Survival rates of remaining teeth were calculated in three subcategories: (1) whole remaining teeth, (2) adjacent teeth to intended edentulous space, and (3) opposing teeth to intended edentulous space. The ten-year cumulative survival rate of the whole remaining teeth was significantly higher in the IFD group (40.0%) than in the RPD group (24.4%). On the other hand, there was no significant difference between two groups in the survival rate of teeth adjacent or opposing to intended edentulous space. A Cox proportional hazard analysis revealed that RPD restoration and gender (male) were the significant risk factors for remaining tooth loss (whole remaining teeth). These results suggest that IFD treatment can reduce the incidence of remaining tooth loss in large edentulous cases."},"publication_date":"2013-07-07","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.57","number":"No.3","starting_page":"157","ending_page":"161","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2013.03.003"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:120, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23311869","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=258982","label":"url"}],"paper_title":{"en":"Identification of risk factors for fracture of veneering materials and screw loosening of implant supported fixed partial dentures in partially edentulous cases","ja":"Identification of risk factors for fracture of veneering materials and screw loosening of implant supported fixed partial dentures in partially edentulous cases"},"authors":{"en":[{"name":"Noda Kinji"},{"name":"Arakawa Hikaru"},{"name":"Maekawa Kenji"},{"name":"Hara S Emilio"},{"name":"Yamazaki Seiya"},{"name":"Kimura-Ono Aya"},{"name":"Sonoyama Wataru"},{"name":"Minakuchi Hajime"},{"name":"Matsuka Yoshizo"},{"name":"Kuboki Takuo"}],"ja":[{"name":"Noda Kinji"},{"name":"Arakawa Hikaru"},{"name":"Maekawa Kenji"},{"name":"Hara S Emilio"},{"name":"Yamazaki Seiya"},{"name":"Kimura-Ono Aya"},{"name":"Sonoyama Wataru"},{"name":"Minakuchi Hajime"},{"name":"松香 芳三"},{"name":"Kuboki Takuo"}]},"description":{"en":"This retrospective study identified the risk factors for fracture of veneering materials and screw loosening of implant-supported fixed partial dentures in partially edentulous cases. The study group included a total of 182 patients who were installed 219 suprastructures at the Fixed Prosthodontic Clinic of Okayama University Dental Hospital between February 1990 and March 2005 and were subdivided in two subgroups: 120 patients (149 facing suprastructures) were included in the subgroup to investigate the risk factors of fracture of veneering materials, and 81 patients (92 suprastructures) were included in the subgroup to identify the risk factors of abutment screw loosening. Each patient was followed up from the day of suprastructure installation until March, 2005. A Cox proportional hazards regression model was used to identify the risk factors related to technical complications, and eight factors were regarded as candidate risk factors. Screw retention was the significant risk factor for fracture of veneering materials, whereas connection of suprastructures with natural tooth was the significant risk factor for screw loosening. It was suggested that screw retention was a significant risk factor for the fracture of veneering materials, and connection of suprastructures with natural tooth was a significant risk factor for screw loosening. Future studies, involving dynamic factors (e.g. bruxism) as predictors as well, are more helpful to discuss the risk factor of fracture of veneering materials and screw loosening.","ja":"This retrospective study identified the risk factors for fracture of veneering materials and screw loosening of implant-supported fixed partial dentures in partially edentulous cases. The study group included a total of 182 patients who were installed 219 suprastructures at the Fixed Prosthodontic Clinic of Okayama University Dental Hospital between February 1990 and March 2005 and were subdivided in two subgroups: 120 patients (149 facing suprastructures) were included in the subgroup to investigate the risk factors of fracture of veneering materials, and 81 patients (92 suprastructures) were included in the subgroup to identify the risk factors of abutment screw loosening. Each patient was followed up from the day of suprastructure installation until March, 2005. A Cox proportional hazards regression model was used to identify the risk factors related to technical complications, and eight factors were regarded as candidate risk factors. Screw retention was the significant risk factor for fracture of veneering materials, whereas connection of suprastructures with natural tooth was the significant risk factor for screw loosening. It was suggested that screw retention was a significant risk factor for the fracture of veneering materials, and connection of suprastructures with natural tooth was a significant risk factor for screw loosening. Future studies, involving dynamic factors (e.g. bruxism) as predictors as well, are more helpful to discuss the risk factor of fracture of veneering materials and screw loosening."},"publication_date":"2013-03","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.40","number":"No.3","starting_page":"214","ending_page":"220","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/joor.12029"],"issn":["1365-2842"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:121, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/114767","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23384362","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=259758","label":"url"}],"paper_title":{"en":"Self-reported aural symptoms, headache and temporomandibular disorders in Japanese young adults","ja":"Self-reported aural symptoms, headache and temporomandibular disorders in Japanese young adults"},"authors":{"en":[{"name":"Akhter R"},{"name":"Morita M"},{"name":"Ekuni D"},{"name":"Hassan NM"},{"name":"Furuta M"},{"name":"Yamanaka R"},{"name":"Matsuka Yoshizo"},{"name":"Wilson D"}],"ja":[{"name":"Akhter R"},{"name":"Morita M"},{"name":"Ekuni D"},{"name":"Hassan NM"},{"name":"Furuta M"},{"name":"Yamanaka R"},{"name":"松香 芳三"},{"name":"Wilson D"}]},"description":{"en":"To investigate the associations of aural symptoms, headache and depression with the presence of temporomandibular disorder (TMD) symptoms in a young adult population in Japan. A personal interview survey was conducted on first-year university students (n = 1,930) regarding symptoms of TMD, aural problems, headache, shoulder pain and depression. Logistic regression was applied to assess the associations of these problems with the presence of TMD symptoms after controlling for age and gender. Among the 1,930 students, 543 students exhibited TMD symptoms and were classified into 7 groups: clicking only (Group I, n = 319), pain in the TMJ only (Group II, n = 21), difficulty in mouth opening only (Group III, n = 18), clicking and pain (Group IV, n = 29), clicking and difficulty in mouth opening (Group V, n = 48), difficulty in mouth opening and pain (Group VI, n = 11), and combination of three symptoms (Group VII, n = 97). The control group (n = 1,387) were subjects without any TMD symptoms. After adjusting for age and gender, a strong association was observed between TMD symptoms (Group II and IV) and tinnitus (OR = 12.1 and 13.2, respectively). TMD symptoms (Group I, II and III) were also associated with vertigo and headache. Otalgia and depression were significantly associated with the presence of clicking only. TMD symptoms were significantly correlated to aural symptoms and headache. A functional evaluation of the stomatognathic system should be considered in subjects with unexplained aural symptoms and headache.","ja":"To investigate the associations of aural symptoms, headache and depression with the presence of temporomandibular disorder (TMD) symptoms in a young adult population in Japan. A personal interview survey was conducted on first-year university students (n = 1,930) regarding symptoms of TMD, aural problems, headache, shoulder pain and depression. Logistic regression was applied to assess the associations of these problems with the presence of TMD symptoms after controlling for age and gender. Among the 1,930 students, 543 students exhibited TMD symptoms and were classified into 7 groups: clicking only (Group I, n = 319), pain in the TMJ only (Group II, n = 21), difficulty in mouth opening only (Group III, n = 18), clicking and pain (Group IV, n = 29), clicking and difficulty in mouth opening (Group V, n = 48), difficulty in mouth opening and pain (Group VI, n = 11), and combination of three symptoms (Group VII, n = 97). The control group (n = 1,387) were subjects without any TMD symptoms. After adjusting for age and gender, a strong association was observed between TMD symptoms (Group II and IV) and tinnitus (OR = 12.1 and 13.2, respectively). TMD symptoms (Group I, II and III) were also associated with vertigo and headache. Otalgia and depression were significantly associated with the presence of clicking only. TMD symptoms were significantly correlated to aural symptoms and headache. A functional evaluation of the stomatognathic system should be considered in subjects with unexplained aural symptoms and headache."},"publication_date":"2013-02-06","publication_name":{"en":"BMC Musculoskeletal Disorders","ja":"BMC Musculoskeletal Disorders"},"volume":"Vol.14","number":"No.1","starting_page":"58","ending_page":"58","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1186/1471-2474-14-58"],"issn":["1471-2474"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:122, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23626980","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84880619876&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264030","label":"url"}],"paper_title":{"en":"A retrospective comparative 8-year study of cumulative complications in teeth adjacent to both natural and implant-supported fixed partial dentures","ja":"A retrospective comparative 8-year study of cumulative complications in teeth adjacent to both natural and implant-supported fixed partial dentures"},"authors":{"en":[{"name":"Yamazaki S"},{"name":"Arakawa H"},{"name":"Maekawa K"},{"name":"Noda K"},{"name":"Hara ES"},{"name":"Minakuchi H"},{"name":"Sonoyama W"},{"name":"Matsuka Yoshizo"},{"name":"Kuboki T"}],"ja":[{"name":"Yamazaki S"},{"name":"Arakawa H"},{"name":"Maekawa K"},{"name":"Noda K"},{"name":"Hara ES"},{"name":"Minakuchi H"},{"name":"Sonoyama W"},{"name":"松香 芳三"},{"name":"Kuboki T"}]},"description":{"en":"To compare the complication rate of natural teeth adjacent to implant supported dentures (IFDs) with that of teeth serving as abutments for fixed partial dentures (FPDs). The second goal was to assess the risk factors for complications in teeth adjacent to bounded edentulous spaces. The study subjects were selected from patients who received prosthodontic treatment for their bounded edentulous space not exceeding two missing teeth between February 1990 and March 2007. Sixty-one patients were included in the IFD group and 66 patients were included in the FPD group. Tooth complications were defined as tooth extraction, periodontal lesion, periapical lesion, and loss of prosthesis and were assessed by one examiner based on dental records. The 8-year cumulative complication rate for the IFD group (7.9%) was significantly lower than for the FPD group (40.7%). Additionally, the 8-year cumulative complication rate of vital teeth (6%) was significantly lower than that of nonvital teeth (45.9%). A cox proportional hazard analysis revealed that nonvitality of dental pulp was a significant risk factor for tooth complications, whereas treatment modality was not. Teeth adjacent to IFD-treated edentulous spaces presented fewer complications than natural teeth serving as abutments for FPDs. Conservation of teeth adjacent to edentulous spaces as vital teeth was the key finding to limit further tooth loss.","ja":"To compare the complication rate of natural teeth adjacent to implant supported dentures (IFDs) with that of teeth serving as abutments for fixed partial dentures (FPDs). The second goal was to assess the risk factors for complications in teeth adjacent to bounded edentulous spaces. The study subjects were selected from patients who received prosthodontic treatment for their bounded edentulous space not exceeding two missing teeth between February 1990 and March 2007. Sixty-one patients were included in the IFD group and 66 patients were included in the FPD group. Tooth complications were defined as tooth extraction, periodontal lesion, periapical lesion, and loss of prosthesis and were assessed by one examiner based on dental records. The 8-year cumulative complication rate for the IFD group (7.9%) was significantly lower than for the FPD group (40.7%). Additionally, the 8-year cumulative complication rate of vital teeth (6%) was significantly lower than that of nonvital teeth (45.9%). A cox proportional hazard analysis revealed that nonvitality of dental pulp was a significant risk factor for tooth complications, whereas treatment modality was not. Teeth adjacent to IFD-treated edentulous spaces presented fewer complications than natural teeth serving as abutments for FPDs. Conservation of teeth adjacent to edentulous spaces as vital teeth was the key finding to limit further tooth loss."},"publication_date":"2013","publication_name":{"en":"The International Journal of Prosthodontics","ja":"The International Journal of Prosthodontics"},"volume":"Vol.26","number":"No.3","starting_page":"260","ending_page":"264","languages":["eng"],"referee":true,"identifiers":{"doi":["10.11607/ijp.3120"],"issn":["0893-2174"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:123, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23225677","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84871046717&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=258981","label":"url"}],"paper_title":{"en":"A Problem-Based Learning Tutorial for Dental Students Regarding Elderly Residents in a Nursing Home in Japan","ja":"A Problem-Based Learning Tutorial for Dental Students Regarding Elderly Residents in a Nursing Home in Japan"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Nakajima Ryu"},{"name":"Miki Haruna"},{"name":"Kimura Aya"},{"name":"Kanyama Manabu"},{"name":"Minakuchi Hajime"},{"name":"Shinkawa Shigehiko"},{"name":"Takiuchi Hiroya"},{"name":"Nawachi Kumiko"},{"name":"Maekawa Kenji"},{"name":"Arakawa Hikaru"},{"name":"Fujisawa Takuo"},{"name":"Sonoyama Wataru"},{"name":"Mine Atsushi"},{"name":"Hara S Emilio"},{"name":"Kikutani Takeshi"},{"name":"Kuboki Takuo"}],"ja":[{"name":"松香 芳三"},{"name":"Nakajima Ryu"},{"name":"Miki Haruna"},{"name":"Kimura Aya"},{"name":"Kanyama Manabu"},{"name":"Minakuchi Hajime"},{"name":"Shinkawa Shigehiko"},{"name":"Takiuchi Hiroya"},{"name":"Nawachi Kumiko"},{"name":"Maekawa Kenji"},{"name":"Arakawa Hikaru"},{"name":"Fujisawa Takuo"},{"name":"Sonoyama Wataru"},{"name":"Mine Atsushi"},{"name":"Hara S Emilio"},{"name":"Kikutani Takeshi"},{"name":"Kuboki Takuo"}]},"description":{"en":"This educational trial was an eight-day problem-based learning (PBL) course for fourth-year predoctoral students at Okayama University's dental school who interviewed elderly residents living in a nursing home. The purpose of this PBL course was to introduce geriatric dentistry to the students by allowing them, independently, to discover the clinical problems of elderly patients as well as the solutions. The sixty-five students were divided into nine small groups and received patient information (age, gender, degree of care needed, medical history, food type, medications, and oral condition) in datasheets before visiting the nursing home. Each group of students directly interviewed one patient and the caregivers and identified the patient's medical, psychological, and social problems. After the interview, the students participated in a PBL tutorial to delineate a management approach for the patient's problems. To measure the efficacy of this program, the students completed a questionnaire before and after the course regarding their level of understanding of and attitudes toward geriatric dentistry, clinical research, and self-study. The results showed that student's perceptions of their knowledge about and attitudes toward oral health care for the elderly significantly increased after the PBL course, which suggests that such tutorials should be an option for dental curricula.","ja":"This educational trial was an eight-day problem-based learning (PBL) course for fourth-year predoctoral students at Okayama University's dental school who interviewed elderly residents living in a nursing home. The purpose of this PBL course was to introduce geriatric dentistry to the students by allowing them, independently, to discover the clinical problems of elderly patients as well as the solutions. The sixty-five students were divided into nine small groups and received patient information (age, gender, degree of care needed, medical history, food type, medications, and oral condition) in datasheets before visiting the nursing home. Each group of students directly interviewed one patient and the caregivers and identified the patient's medical, psychological, and social problems. After the interview, the students participated in a PBL tutorial to delineate a management approach for the patient's problems. To measure the efficacy of this program, the students completed a questionnaire before and after the course regarding their level of understanding of and attitudes toward geriatric dentistry, clinical research, and self-study. The results showed that student's perceptions of their knowledge about and attitudes toward oral health care for the elderly significantly increased after the PBL course, which suggests that such tutorials should be an option for dental curricula."},"publication_date":"2012-12","publication_name":{"en":"Journal of Dental Education","ja":"Journal of Dental Education"},"volume":"Vol.76","number":"No.12","starting_page":"1580","ending_page":"1588","languages":["eng"],"referee":true,"identifiers":{"issn":["0022-0337"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:124, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=258256","label":"url"}],"paper_title":{"en":"主機能部位でのストッピング嚙みしめ時の顆頭運動","ja":"主機能部位でのストッピング嚙みしめ時の顆頭運動"},"authors":{"en":[{"name":"Satsuma Toyoko"},{"name":"Shigemoto Shuji"},{"name":"Ishikawa Teruaki"},{"name":"Matsuka Yoshizo"},{"name":"Matsuyama Miwa"},{"name":"Nakano Masanori"},{"name":"Bando Eiichi"},{"name":"Fujimura Tetsuya"}],"ja":[{"name":"薩摩 登誉子"},{"name":"重本 修伺"},{"name":"石川 輝明"},{"name":"松香 芳三"},{"name":"松山 美和"},{"name":"中野 雅德"},{"name":"坂東 永一"},{"name":"藤村 哲也"}]},"publication_date":"2012-10-30","publication_name":{"en":"日本顎口腔機能学会雑誌","ja":"日本顎口腔機能学会雑誌"},"volume":"Vol.19","number":"No.1","starting_page":"19","ending_page":"27","languages":["jpn"],"referee":true,"published_paper_type":"scientific_journal"},"priority":"input_data"} line:125, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23083963","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=258260","label":"url"}],"paper_title":{"en":"Matrix metalloproteinase-8 is the major potential collagenase in active peri-implantitis.","ja":"Matrix metalloproteinase-8 is the major potential collagenase in active peri-implantitis."},"authors":{"en":[{"name":"Arakawa Hikaru"},{"name":"Uehara Junji"},{"name":"Hara Satoshi Emilio"},{"name":"Sonoyama Wataru"},{"name":"Kimura Aya"},{"name":"Kanyama Manabu"},{"name":"Matsuka Yoshizo"},{"name":"Kuboki Takuo"}],"ja":[{"name":"Arakawa Hikaru"},{"name":"Uehara Junji"},{"name":"Hara Satoshi Emilio"},{"name":"Sonoyama Wataru"},{"name":"Kimura Aya"},{"name":"Kanyama Manabu"},{"name":"松香 芳三"},{"name":"Kuboki Takuo"}]},"description":{"en":"PURPOSE: Current clinical procedures to control or regenerate bone loss due to peri-implantitis are not predictable neither accomplish complete resolution. Therefore, early detection of the onset and the active periods of bone loss are crucial for prevention of extensive peri-implant bone resorption. This study aimed to determine a possible association between the presence of collagenases (MMP-1, MMP-8 and MMP-13) in peri-implant sulcular fluid (PISF) and active periods of bone loss by annually adjusted vertical bone loss (AVBL) measurements. METHODS: Intended sample consisted of 76 consecutive patients who received oral implant treatment at the Fixed Prosthodontic Clinic of Okayama University Hospital from 1990 to 2000. Twelve subjects were lost to follow-up or refused to participate. Consequently, the actual sample consisted of 64 patients who were followed-up for at least one year. Those patients with AVBL>0.6mm were included in the severe peri-implantitis group, and randomly selected, age-, gender- and implantation site-matched healthy patients (AVBL<0.3mm) comprised the control group. PISF samples were collected from both groups and further analyzed by western blot for detection of collagenases. RESULTS: Four patients presented severe peri-implantitis. MMP-8 was the only collagenase detected in peri-implant sites with ongoing bone loss. PISF samples from control group showed no positive reactions to any collagenase. CONCLUSION: This study showed MMP-8 as a possible marker for progressive bone loss in peri-implantitis.","ja":"PURPOSE: Current clinical procedures to control or regenerate bone loss due to peri-implantitis are not predictable neither accomplish complete resolution. Therefore, early detection of the onset and the active periods of bone loss are crucial for prevention of extensive peri-implant bone resorption. This study aimed to determine a possible association between the presence of collagenases (MMP-1, MMP-8 and MMP-13) in peri-implant sulcular fluid (PISF) and active periods of bone loss by annually adjusted vertical bone loss (AVBL) measurements. METHODS: Intended sample consisted of 76 consecutive patients who received oral implant treatment at the Fixed Prosthodontic Clinic of Okayama University Hospital from 1990 to 2000. Twelve subjects were lost to follow-up or refused to participate. Consequently, the actual sample consisted of 64 patients who were followed-up for at least one year. Those patients with AVBL>0.6mm were included in the severe peri-implantitis group, and randomly selected, age-, gender- and implantation site-matched healthy patients (AVBL<0.3mm) comprised the control group. PISF samples were collected from both groups and further analyzed by western blot for detection of collagenases. RESULTS: Four patients presented severe peri-implantitis. MMP-8 was the only collagenase detected in peri-implant sites with ongoing bone loss. PISF samples from control group showed no positive reactions to any collagenase. CONCLUSION: This study showed MMP-8 as a possible marker for progressive bone loss in peri-implantitis."},"publication_date":"2012-10-17","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.56","number":"No.4","starting_page":"249","ending_page":"255","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jpor.2012.07.002"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:126, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797085"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=258141","label":"url"}],"paper_title":{"en":"下顎左側大臼歯欠損にインプラント義歯による機能回復を行なった一症例","ja":"下顎左側大臼歯欠損にインプラント義歯による機能回復を行なった一症例"},"authors":{"en":[{"name":"Matsuka Yoshizo"}],"ja":[{"name":"松香 芳三"}]},"publication_date":"2012-09-30","publication_name":{"en":"Journal of Japanese Society of Oral Implantology","ja":"日本口腔インプラント学会誌"},"volume":"Vol.25","number":"No.3","starting_page":"675","ending_page":"676","languages":["jpn"],"referee":true,"identifiers":{"issn":["0914-6695"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:127, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/22745637","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249576","label":"url"}],"paper_title":{"en":"Application of Purified Botulinum Type A Neurotoxin to Treat Experimental Trigeminal Neuropathy in Rats and Patients with Urinary Incontinence and Prostatic Hyperplasia.","ja":"Application of Purified Botulinum Type A Neurotoxin to Treat Experimental Trigeminal Neuropathy in Rats and Patients with Urinary Incontinence and Prostatic Hyperplasia."},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Yokoyama Teruhiko"},{"name":"Yamamoto Yumiko"},{"name":"Suzuki Tomonori"},{"name":"Dwi Fatmawati Ni Nengah"},{"name":"Nishikawa Atsushi"},{"name":"Ohyama Tohru"},{"name":"Watanabe Toshihiro"},{"name":"Kuboki Takuo"},{"name":"Nagai Atsushi"},{"name":"Oguma Keiji"}],"ja":[{"name":"松香 芳三"},{"name":"Yokoyama Teruhiko"},{"name":"Yamamoto Yumiko"},{"name":"Suzuki Tomonori"},{"name":"Dwi Fatmawati Ni Nengah"},{"name":"Nishikawa Atsushi"},{"name":"Ohyama Tohru"},{"name":"Watanabe Toshihiro"},{"name":"Kuboki Takuo"},{"name":"Nagai Atsushi"},{"name":"Oguma Keiji"}]},"description":{"en":"Type A neurotoxin (NTX) of Clostridium botulinum was purified by a simple procedure using a lactose gel column. The toxicity of this purified toxin preparation was retained for at least 1 year at -30°C by supplementation with either 0.1% albumin or 0.05% albumin plus 1% trehalose. When purified NTX was used to treat 49 patients with urinary incontinence caused by either refractory idiopathic or neurogenic detrusor overactivity, 36 patients showed significant improvement in symptoms. These beneficial effects were also observed in cases of prostatic hyperplasia. The results obtained with NTX were similar to that of Botox. The effects of NTX on trigeminal neuralgia induced by infraorbital nerve constriction (IoNC) in rats were also studied. Trigeminal ganglion neurons from ipsilateral to IoNC exhibited significantly faster onset of FM4-64 release than sham-operated contralateral neurons. Intradermal injection of NTX in the area of IoNC alleviated IoNC-induced pain behavior and reduced the exaggerated FM4-64 release in trigeminal ganglion neurons.","ja":"Type A neurotoxin (NTX) of Clostridium botulinum was purified by a simple procedure using a lactose gel column. The toxicity of this purified toxin preparation was retained for at least 1 year at -30°C by supplementation with either 0.1% albumin or 0.05% albumin plus 1% trehalose. When purified NTX was used to treat 49 patients with urinary incontinence caused by either refractory idiopathic or neurogenic detrusor overactivity, 36 patients showed significant improvement in symptoms. These beneficial effects were also observed in cases of prostatic hyperplasia. The results obtained with NTX were similar to that of Botox. The effects of NTX on trigeminal neuralgia induced by infraorbital nerve constriction (IoNC) in rats were also studied. Trigeminal ganglion neurons from ipsilateral to IoNC exhibited significantly faster onset of FM4-64 release than sham-operated contralateral neurons. Intradermal injection of NTX in the area of IoNC alleviated IoNC-induced pain behavior and reduced the exaggerated FM4-64 release in trigeminal ganglion neurons."},"publication_date":"2012-06-14","publication_name":{"en":"Journal of Toxicology","ja":"Journal of Toxicology"},"volume":"Vol.2012","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1155/2012/648384"],"issn":["1687-8205"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:128, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/22506934","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249578","label":"url"}],"paper_title":{"en":"Occlusal dysesthesia: a qualitative systematic review of the epidemiology, aetiology and management.","ja":"Occlusal dysesthesia: a qualitative systematic review of the epidemiology, aetiology and management."},"authors":{"en":[{"name":"Hara ES"},{"name":"Matsuka Yoshizo"},{"name":"Minakuchi H"},{"name":"Clark GT"},{"name":"Kuboki T"}],"ja":[{"name":"Hara ES"},{"name":"松香 芳三"},{"name":"Minakuchi H"},{"name":"Clark GT"},{"name":"Kuboki T"}]},"description":{"en":"Summary Occlusal dysesthesia refers to a persistent complaint of uncomfortable bite sensation with no obvious occlusal discrepancy. This systematic review aimed to draw a picture of such patients, to present an agreement of previously reported diagnostic criteria and to analyse the evidence level of the recommended management approaches. An electronic search for all relevant reports on occlusal dysesthesia was thoroughly performed based on previous nomenclatures (e.g. phantom bite, occlusal hyperawareness) in PubMed and The Cochrane Library in July, 2011. A total of 84 reports were matched, among which only 11 studies were included after a two-step (abstract and detailed full-text revision) screening process. Additionally, a thorough manual review of reference lists of the included reports enabled the inclusion of two additional studies. Data analysis revealed that 37 occlusal dysesthesia patients presented a mean age of 51·7 ± 10·6 years and were predominantly women (male/female: 1/5·1) with symptom duration of more than 6 years (average: 6·3 ± 7·5 years) and with concomitant psychological disturbances (e.g. mood disorders, somatoform disorders, personality disorders). Only four authors presented diagnostic criteria for occlusal dysesthesia, which served as the basis for an agreement in the diagnostic criteria. Treatment approaches included psychotherapy, cognitive/behaviour therapy, splint therapy and prescription of anti-depressants or anti-anxiety drugs. Classification of evidence level of management approaches, however, revealed that most of them were expert opinions with single- or multiple-case report(s). Future studies are necessary for a deeper understanding of the mechanisms behind the occlusal dysesthesia symptoms, and consequently, for improvements in evidence-based management approaches.","ja":"Summary Occlusal dysesthesia refers to a persistent complaint of uncomfortable bite sensation with no obvious occlusal discrepancy. This systematic review aimed to draw a picture of such patients, to present an agreement of previously reported diagnostic criteria and to analyse the evidence level of the recommended management approaches. An electronic search for all relevant reports on occlusal dysesthesia was thoroughly performed based on previous nomenclatures (e.g. phantom bite, occlusal hyperawareness) in PubMed and The Cochrane Library in July, 2011. A total of 84 reports were matched, among which only 11 studies were included after a two-step (abstract and detailed full-text revision) screening process. Additionally, a thorough manual review of reference lists of the included reports enabled the inclusion of two additional studies. Data analysis revealed that 37 occlusal dysesthesia patients presented a mean age of 51·7 ± 10·6 years and were predominantly women (male/female: 1/5·1) with symptom duration of more than 6 years (average: 6·3 ± 7·5 years) and with concomitant psychological disturbances (e.g. mood disorders, somatoform disorders, personality disorders). Only four authors presented diagnostic criteria for occlusal dysesthesia, which served as the basis for an agreement in the diagnostic criteria. Treatment approaches included psychotherapy, cognitive/behaviour therapy, splint therapy and prescription of anti-depressants or anti-anxiety drugs. Classification of evidence level of management approaches, however, revealed that most of them were expert opinions with single- or multiple-case report(s). Future studies are necessary for a deeper understanding of the mechanisms behind the occlusal dysesthesia symptoms, and consequently, for improvements in evidence-based management approaches."},"publication_date":"2012-04-17","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.39","number":"No.8","starting_page":"630","ending_page":"638","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/j.1365-2842.2012.02300.x"],"issn":["1365-2842"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:129, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/22278147","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249579","label":"url"}],"paper_title":{"en":"Multiple sleep bruxism data collected using a self-contained EMG detector/analyzer system in asymptomatic healthy subjects.","ja":"Multiple sleep bruxism data collected using a self-contained EMG detector/analyzer system in asymptomatic healthy subjects."},"authors":{"en":[{"name":"Minakuchi Hajime"},{"name":"Sakaguchi Chiyomi"},{"name":"Hara ES"},{"name":"Maekawa Kenji"},{"name":"Matsuka Yoshizo"},{"name":"Clark GT"},{"name":"Kuboki Takuo"}],"ja":[{"name":"Minakuchi Hajime"},{"name":"Sakaguchi Chiyomi"},{"name":"Hara ES"},{"name":"Maekawa Kenji"},{"name":"松香 芳三"},{"name":"Clark GT"},{"name":"Kuboki Takuo"}]},"description":{"en":"PURPOSE: Small, self-contained electromyographic (EMG) detector/analyzer (D/A) devices have become available for the detection of jaw muscle activity events above threshold. These devices claim to be less intrusive to the subjects sleep so it is less prone to induce disturbed sleep. The objective of this study was to evaluate for night-to-night variability and examine for a systematic alteration on the first night in EMG levels. METHODS: Ten asymptomatic healthy volunteers (mean age, 26.8 ± 3.78) were recorded for six sequential nights in their home environment using EMG D/A system. The device yields a nightly EMG level above threshold score on a 0-4 level. Because the data are categorical and nonparametric, the data of the ten subjects across six nights were submitted to a Friedman repeated measures ANOVA. The significant level was set as alpha equal to 0.05. RESULTS: The median and mode values of the subjects were tabulated and analyzed and we did not find a significant difference in EMG D/A level across the six nights (p = 0.287, Kendall's coefficient of concordance = 0.124, Friedman two-way repeated measures ANOVA). The data did show clear and substantial night-to-night variability. CONCLUSION: Substantial night-to-night variability in masseter EMG activity levels was clearly observed in our subjects. There was no evidence of a suppressed or elevated first-night effect-like variability on masseter muscle EMG level seen in these subjects using a small portable self-contained EMG detector/analyzer. These data suggest that recordings should be at least 5-6-nights duration to establish a reasonable measure of an individual's average nightly masseter EMG level.","ja":"PURPOSE: Small, self-contained electromyographic (EMG) detector/analyzer (D/A) devices have become available for the detection of jaw muscle activity events above threshold. These devices claim to be less intrusive to the subjects sleep so it is less prone to induce disturbed sleep. The objective of this study was to evaluate for night-to-night variability and examine for a systematic alteration on the first night in EMG levels. METHODS: Ten asymptomatic healthy volunteers (mean age, 26.8 ± 3.78) were recorded for six sequential nights in their home environment using EMG D/A system. The device yields a nightly EMG level above threshold score on a 0-4 level. Because the data are categorical and nonparametric, the data of the ten subjects across six nights were submitted to a Friedman repeated measures ANOVA. The significant level was set as alpha equal to 0.05. RESULTS: The median and mode values of the subjects were tabulated and analyzed and we did not find a significant difference in EMG D/A level across the six nights (p = 0.287, Kendall's coefficient of concordance = 0.124, Friedman two-way repeated measures ANOVA). The data did show clear and substantial night-to-night variability. CONCLUSION: Substantial night-to-night variability in masseter EMG activity levels was clearly observed in our subjects. There was no evidence of a suppressed or elevated first-night effect-like variability on masseter muscle EMG level seen in these subjects using a small portable self-contained EMG detector/analyzer. These data suggest that recordings should be at least 5-6-nights duration to establish a reasonable measure of an individual's average nightly masseter EMG level."},"publication_date":"2012-01-26","publication_name":{"en":"Sleep & Breathing = Schlaf & Atmung","ja":"Sleep & Breathing = Schlaf & Atmung"},"volume":"Vol.16","number":"No.4","starting_page":"1069","ending_page":"1072","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s11325-011-0602-1"],"issn":["1522-1709"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:130, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/22277610","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249580","label":"url"}],"paper_title":{"en":"Influence of resin coating materials on Porphyromonas gingivalis attachment.","ja":"Influence of resin coating materials on Porphyromonas gingivalis attachment."},"authors":{"en":[{"name":"Kumada Ai"},{"name":"Matsuka Yoshizo"},{"name":"Mine Atsushi"},{"name":"Ono Mitsuaki"},{"name":"Uehara Junji"},{"name":"Sonoi Norihiro"},{"name":"Ito Takashi"},{"name":"Takashiba Shogo"},{"name":"Kuboki Takuo"}],"ja":[{"name":"Kumada Ai"},{"name":"松香 芳三"},{"name":"Mine Atsushi"},{"name":"Ono Mitsuaki"},{"name":"Uehara Junji"},{"name":"Sonoi Norihiro"},{"name":"Ito Takashi"},{"name":"Takashiba Shogo"},{"name":"Kuboki Takuo"}]},"description":{"en":"Resin coating materials have been used for composite resin or provisional restoration in order to prevent plaque accumulation on their surfaces. However, it is not clear whether the coating materials influence attachment of periodontal bacteria. Therefore, we investigated the effect of resin coating materials on the attachment of Porphyromonas gingivalis (Pg). The polymerized auto cure resin plates were coated with two resin coating materials. To estimate the Pg attachment, each plate was immersed in brain heart infusion medium containing Pg. The quantity of bacteria attached on each plate was evaluated by crystal violet quantification. Morphological change of Pg was recorded using scanning electron microscopy. Both coating groups presented significantly lower Pg attachment compared to the control. The Pg shapes on the plates with resin coating materials were similar to the non-treated control plates. The resin coating materials clearly prevent Pg attachment on the polymerized auto cure resin plate.","ja":"Resin coating materials have been used for composite resin or provisional restoration in order to prevent plaque accumulation on their surfaces. However, it is not clear whether the coating materials influence attachment of periodontal bacteria. Therefore, we investigated the effect of resin coating materials on the attachment of Porphyromonas gingivalis (Pg). The polymerized auto cure resin plates were coated with two resin coating materials. To estimate the Pg attachment, each plate was immersed in brain heart infusion medium containing Pg. The quantity of bacteria attached on each plate was evaluated by crystal violet quantification. Morphological change of Pg was recorded using scanning electron microscopy. Both coating groups presented significantly lower Pg attachment compared to the control. The Pg shapes on the plates with resin coating materials were similar to the non-treated control plates. The resin coating materials clearly prevent Pg attachment on the polymerized auto cure resin plate."},"publication_date":"2012-01-21","publication_name":{"en":"Dental Materials Journal","ja":"Dental Materials Journal"},"volume":"Vol.31","number":"No.1","starting_page":"86","ending_page":"91","languages":["eng"],"referee":true,"identifiers":{"doi":["10.4012/dmj.2011-164"],"issn":["1881-1361"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:131, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/21827524","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249581","label":"url"}],"paper_title":{"en":"Response shift in oral health-related quality of life measurement in patients with partial edentulism.","ja":"Response shift in oral health-related quality of life measurement in patients with partial edentulism."},"authors":{"en":[{"name":"Kimura A"},{"name":"Arakawa H"},{"name":"Noda K"},{"name":"Yamazaki S"},{"name":"Hara E S"},{"name":"Mino T"},{"name":"Matsuka Yoshizo"},{"name":"Mulligan R"},{"name":"Kuboki T"}],"ja":[{"name":"Kimura A"},{"name":"Arakawa H"},{"name":"Noda K"},{"name":"Yamazaki S"},{"name":"Hara E S"},{"name":"Mino T"},{"name":"松香 芳三"},{"name":"Mulligan R"},{"name":"Kuboki T"}]},"description":{"en":"The purposes of this study were to determine whether a response shift was observable after partial denture treatment and to identify the predictors that influenced the response shift magnitude and direction. A total of 173 consecutive patients with no more than eight missing teeth who received implant-supported, fixed or removable partial dentures at Okayama University Dental Hospital were asked to complete a full-version Oral Health-Related Quality of Life (OHRQoL) questionnaire before (pre-test) and after treatment (post-test). Additionally, a short form (then-test) consisting of seven questions selected from the full version had its reliability verified and was utilised to retrospectively assess the pre-treatment OHRQoL status. The difference between the summary scores of the then-test and the pre-test determined the response shift magnitude and direction. The then-test mean score (22·9 ± 6·6) was significantly lower (worse OHRQoL) than that of the pre-test (26·4 ± 5·2). The response shift effect size was of moderate magnitude and negative direction (d = -0·78). A multiple regression analysis showed that age (younger patients) (P < 0·01), number of replaced teeth (fewer) (P < 0·01) and pre-test scores (lower) (P < 0·01) were the significant predictors for response shift. In conclusion, a response shift phenomenon with negative and moderate effect size was observed after partial denture treatment. The significant predictor variables were young age, fewer numbers of replaced teeth and lower pre-test scores.","ja":"The purposes of this study were to determine whether a response shift was observable after partial denture treatment and to identify the predictors that influenced the response shift magnitude and direction. A total of 173 consecutive patients with no more than eight missing teeth who received implant-supported, fixed or removable partial dentures at Okayama University Dental Hospital were asked to complete a full-version Oral Health-Related Quality of Life (OHRQoL) questionnaire before (pre-test) and after treatment (post-test). Additionally, a short form (then-test) consisting of seven questions selected from the full version had its reliability verified and was utilised to retrospectively assess the pre-treatment OHRQoL status. The difference between the summary scores of the then-test and the pre-test determined the response shift magnitude and direction. The then-test mean score (22·9 ± 6·6) was significantly lower (worse OHRQoL) than that of the pre-test (26·4 ± 5·2). The response shift effect size was of moderate magnitude and negative direction (d = -0·78). A multiple regression analysis showed that age (younger patients) (P < 0·01), number of replaced teeth (fewer) (P < 0·01) and pre-test scores (lower) (P < 0·01) were the significant predictors for response shift. In conclusion, a response shift phenomenon with negative and moderate effect size was observed after partial denture treatment. The significant predictor variables were young age, fewer numbers of replaced teeth and lower pre-test scores."},"publication_date":"2011-08-09","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.39","number":"No.1","starting_page":"44","ending_page":"54","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/j.1365-2842.2011.02241.x"],"issn":["1365-2842"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:132, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/21793870","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249582","label":"url"}],"paper_title":{"en":"Intradermal injection of Botulinum toxin type A alleviates infraorbital nerve constriction-induced thermal hyperalgesia in an operant assay.","ja":"Intradermal injection of Botulinum toxin type A alleviates infraorbital nerve constriction-induced thermal hyperalgesia in an operant assay."},"authors":{"en":[{"name":"Kumada A"},{"name":"Matsuka Yoshizo"},{"name":"Spigelman I"},{"name":"Maruhama K"},{"name":"Yamamoto Y"},{"name":"Neubert J K"},{"name":"Nolan T A"},{"name":"Watanabe K"},{"name":"Maekawa K"},{"name":"Kamioka H"},{"name":"Yamashiro T"},{"name":"Kuboki T"},{"name":"Oguma K"}],"ja":[{"name":"Kumada A"},{"name":"松香 芳三"},{"name":"Spigelman I"},{"name":"Maruhama K"},{"name":"Yamamoto Y"},{"name":"Neubert J K"},{"name":"Nolan T A"},{"name":"Watanabe K"},{"name":"Maekawa K"},{"name":"Kamioka H"},{"name":"Yamashiro T"},{"name":"Kuboki T"},{"name":"Oguma K"}]},"description":{"en":"Recent studies have shown that infraorbital nerve constriction (IoNC)-induced mechanical allodynia has been attenuated by administration of highly purified 150-kDa Botulinum neurotoxin type A (BoNT/A). Here, we extend these studies to determine whether BoNT/A could attenuate IoNC-induced symptoms of thermal hyperalgesia. Instead of testing head withdrawal thresholds, a thermal operant assay was used to evaluate cortical processing of sensory input following IoNC. In this assay, a fasted rat's desire to obtain a food reward (sweetened condensed milk) is coupled to its ability to tolerate facial contact with a warm (45 °C) thermode. Bilateral IoNC decreased the ratio of thermode contact duration/event, which is an indicative of thermal hyperalgesia. BoNT/A injection intradermally in the area of infraorbital nerve (IoN) innervation 7 days after IoNC resulted in decreased number of facial contacts and increased the ratio of contact duration/event (measured at 14 days after IoNC). The BoNT/A (2-200 pg) effects were dose dependent and statistically significant at 100 and 200 pg (P < 0·05). Complete reversal of thermal hyperalgesia symptoms was obtained with a 200-pg dose, without affecting sham rat behaviour. Off-site (neck) injection of BoNT/A did not relieve thermal hyperalgesia, while co-injection of BoNT/A with a neutralising antibody in the area of IoN innervation prevented relief of thermal hyperalgesia. Neither IoNC nor BoNT/A injection affected operant assay parameters with a 24 °C thermode, indicating selectivity of thermal hyperalgesia measurements. These results strongly suggest that intradermal injection of BoNT/A in the area of IoN innervation alleviates IoNC-induced thermal hyperalgesia in an operant assay.","ja":"Recent studies have shown that infraorbital nerve constriction (IoNC)-induced mechanical allodynia has been attenuated by administration of highly purified 150-kDa Botulinum neurotoxin type A (BoNT/A). Here, we extend these studies to determine whether BoNT/A could attenuate IoNC-induced symptoms of thermal hyperalgesia. Instead of testing head withdrawal thresholds, a thermal operant assay was used to evaluate cortical processing of sensory input following IoNC. In this assay, a fasted rat's desire to obtain a food reward (sweetened condensed milk) is coupled to its ability to tolerate facial contact with a warm (45 °C) thermode. Bilateral IoNC decreased the ratio of thermode contact duration/event, which is an indicative of thermal hyperalgesia. BoNT/A injection intradermally in the area of infraorbital nerve (IoN) innervation 7 days after IoNC resulted in decreased number of facial contacts and increased the ratio of contact duration/event (measured at 14 days after IoNC). The BoNT/A (2-200 pg) effects were dose dependent and statistically significant at 100 and 200 pg (P < 0·05). Complete reversal of thermal hyperalgesia symptoms was obtained with a 200-pg dose, without affecting sham rat behaviour. Off-site (neck) injection of BoNT/A did not relieve thermal hyperalgesia, while co-injection of BoNT/A with a neutralising antibody in the area of IoN innervation prevented relief of thermal hyperalgesia. Neither IoNC nor BoNT/A injection affected operant assay parameters with a 24 °C thermode, indicating selectivity of thermal hyperalgesia measurements. These results strongly suggest that intradermal injection of BoNT/A in the area of IoN innervation alleviates IoNC-induced thermal hyperalgesia in an operant assay."},"publication_date":"2011-07-27","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.39","number":"No.1","starting_page":"63","ending_page":"72","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/j.1365-2842.2011.02236.x"],"issn":["1365-2842"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:133, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10030470727/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282679309626368/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250040","label":"url"}],"paper_title":{"en":"施設に入所している要介護高齢者の問題点を抽出するテュートリアル演習の試み","ja":"施設に入所している要介護高齢者の問題点を抽出するテュートリアル演習の試み"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"縄稚 久美子"},{"name":"木村 彩"},{"name":"完山 学"},{"name":"水口 一"},{"name":"三野 卓哉"},{"name":"丸濱 功太郎"},{"name":"前川 賢治"},{"name":"藤澤 拓生"},{"name":"園山 亘"},{"name":"峯 篤史"},{"name":"菊谷 武"},{"name":"窪木 拓男"}],"ja":[{"name":"松香 芳三"},{"name":"縄稚 久美子"},{"name":"木村 彩"},{"name":"完山 学"},{"name":"水口 一"},{"name":"三野 卓哉"},{"name":"丸濱 功太郎"},{"name":"前川 賢治"},{"name":"藤澤 拓生"},{"name":"園山 亘"},{"name":"峯 篤史"},{"name":"菊谷 武"},{"name":"窪木 拓男"}]},"publication_date":"2011-06-30","publication_name":{"en":"Japanese Journal of Gerodontology","ja":"老年歯科医学"},"volume":"Vol.26","number":"No.1","starting_page":"36","ending_page":"45","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11259/jsg.26.36"],"issn":["0914-3866"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:134, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/21241350","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249637","label":"url"}],"paper_title":{"en":"Guidelines and recommendations for assessment of somatosensory function in oro-facial pain conditions--a taskforce report.","ja":"Guidelines and recommendations for assessment of somatosensory function in oro-facial pain conditions--a taskforce report."},"authors":{"en":[{"name":"Svensson P"},{"name":"Baad-Hansen L"},{"name":"Pigg M"},{"name":"List T"},{"name":"Eliav E"},{"name":"Ettlin D"},{"name":"Michelotti A"},{"name":"Tsukiyama Y"},{"name":"Matsuka Yoshizo"},{"name":"Jääskeläinen S K"},{"name":"Essick G"},{"name":"Greenspan J D"},{"name":"Drangsholt M"}],"ja":[{"name":"Svensson P"},{"name":"Baad-Hansen L"},{"name":"Pigg M"},{"name":"List T"},{"name":"Eliav E"},{"name":"Ettlin D"},{"name":"Michelotti A"},{"name":"Tsukiyama Y"},{"name":"松香 芳三"},{"name":"Jääskeläinen S K"},{"name":"Essick G"},{"name":"Greenspan J D"},{"name":"Drangsholt M"}]},"description":{"en":"The goals of an international taskforce on somatosensory testing established by the Special Interest Group of Oro-facial Pain (SIG-OFP) under the International Association for the Study of Pain (IASP) were to (i) review the literature concerning assessment of somatosensory function in the oro-facial region in terms of techniques and test performance, (ii) provide guidelines for comprehensive and screening examination procedures, and (iii) give recommendations for future development of somatosensory testing specifically in the oro-facial region. Numerous qualitative and quantitative psychophysical techniques have been proposed and used in the description of oro-facial somatosensory function. The selection of technique includes time considerations because the most reliable and accurate methods require multiple repetitions of stimuli. Multiple-stimulus modalities (mechanical, thermal, electrical, chemical) have been applied to study oro-facial somatosensory function. A battery of different test stimuli is needed to obtain comprehensive information about the functional integrity of the various types of afferent nerve fibres. Based on the available literature, the German Neuropathic Pain Network test battery appears suitable for the study of somatosensory function within the oro-facial area as it is based on a wide variety of both qualitative and quantitative assessments of all cutaneous somatosensory modalities. Furthermore, these protocols have been thoroughly described and tested on multiple sites including the facial skin and intra-oral mucosa. Standardisation of both comprehensive and screening examination techniques is likely to improve the diagnostic accuracy and facilitate the understanding of neural mechanisms and somatosensory changes in different oro-facial pain conditions and may help to guide management.","ja":"The goals of an international taskforce on somatosensory testing established by the Special Interest Group of Oro-facial Pain (SIG-OFP) under the International Association for the Study of Pain (IASP) were to (i) review the literature concerning assessment of somatosensory function in the oro-facial region in terms of techniques and test performance, (ii) provide guidelines for comprehensive and screening examination procedures, and (iii) give recommendations for future development of somatosensory testing specifically in the oro-facial region. Numerous qualitative and quantitative psychophysical techniques have been proposed and used in the description of oro-facial somatosensory function. The selection of technique includes time considerations because the most reliable and accurate methods require multiple repetitions of stimuli. Multiple-stimulus modalities (mechanical, thermal, electrical, chemical) have been applied to study oro-facial somatosensory function. A battery of different test stimuli is needed to obtain comprehensive information about the functional integrity of the various types of afferent nerve fibres. Based on the available literature, the German Neuropathic Pain Network test battery appears suitable for the study of somatosensory function within the oro-facial area as it is based on a wide variety of both qualitative and quantitative assessments of all cutaneous somatosensory modalities. Furthermore, these protocols have been thoroughly described and tested on multiple sites including the facial skin and intra-oral mucosa. Standardisation of both comprehensive and screening examination techniques is likely to improve the diagnostic accuracy and facilitate the understanding of neural mechanisms and somatosensory changes in different oro-facial pain conditions and may help to guide management."},"publication_date":"2011-01-17","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.38","number":"No.5","starting_page":"366","ending_page":"394","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/j.1365-2842.2010.02196.x"],"issn":["1365-2842"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:135, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=253033","label":"url"}],"paper_title":{"en":"非歯原性歯痛のガイドライン","ja":"非歯原性歯痛のガイドライン"},"authors":{"en":[{"name":"和嶋 浩一"},{"name":"矢谷 博文"},{"name":"井川 雅子"},{"name":"小見山 道"},{"name":"坂本 英治"},{"name":"Matsuka Yoshizo"},{"name":"村岡 渡"}],"ja":[{"name":"和嶋 浩一"},{"name":"矢谷 博文"},{"name":"井川 雅子"},{"name":"小見山 道"},{"name":"坂本 英治"},{"name":"松香 芳三"},{"name":"村岡 渡"}]},"publication_date":"2011","publication_name":{"en":"Japanese Journal of Orofacial Pain","ja":"日本口腔顔面痛学会雑誌"},"volume":"Vol.4","number":"No.2","starting_page":"1","ending_page":"88","languages":["jpn"],"referee":true,"identifiers":{"issn":["1883-308X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:136, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10027659873/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282679397900416/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250041","label":"url"}],"paper_title":{"en":"顎関節症の診療ガイドライン作成における\"Patient Question\"収集のための患者ボランティアに対する個別面接調査","ja":"顎関節症の診療ガイドライン作成における\"Patient Question\"収集のための患者ボランティアに対する個別面接調査"},"authors":{"en":[{"name":"木野 孔司"},{"name":"覚道 健治"},{"name":"杉崎 正志"},{"name":"星 佳芳"},{"name":"湯浅 秀道"},{"name":"Matsuka Yoshizo"},{"name":"齋藤 高"},{"name":"西山 暁"}],"ja":[{"name":"木野 孔司"},{"name":"覚道 健治"},{"name":"杉崎 正志"},{"name":"星 佳芳"},{"name":"湯浅 秀道"},{"name":"松香 芳三"},{"name":"齋藤 高"},{"name":"西山 暁"}]},"description":{"en":"With the aim of formulating clinical practice guidelines for the initial treatment of temporomandibular disorders (TMD), we carried out semi-structured interviews with volunteer patients who had suffered from TMD for the purpose of collecting patient question. The subjects (informants) were recruited through two newspapers. The guidelines committee chose 10 subjects from the 19 applicants through careful discussion. The interviews were conducted by trained interviewers in a special interview room, and the answers given by the informants were tape-recorded and transcribed into sentences. From these sentences, important words and phrases were extracted using a text mining method. When asked about their understanding of TMD, four informants answered \"A disease with jaw displacement\" and another four said \"A disease that occurs when one's occlusion is not good.\" Only one informant had been correctly educated about TMD by the dentist. Three informants had received mouthpiece therapy but none knew the importance of and reasons for providing this therapy. Six informants were satisfied with the treatment they had received, but two were not. Usually, mouth-opening exercises, massages, and compresses were chosen as management therapy for problems of joint noise, restriction in mouth opening, or joint pain; this was followed by jaw rest, chiropractic treatment, and mouthpiece therapy. This investigation revealed that all informants had only a superficial knowledge about the pathological conditions and treatment methods for TMD. It is suggested that dentists should provide patients with adequate education regarding the symptoms and treatments of TMD.","ja":"顎関節症に対する初期治療ガイドライン作成における,Patient Question(PQ)収集を目的として,症状経験ボランティア患者への個別面接調査を実施した.対象者(以下インフォーマントと呼ぶ)を新聞紙上で募集した.19名の応募者の内10名(女性9名,男性1名)を委員会において検討したうえでインフォーマントと選定した.この10名に対する個別面接調査は,専用施設を用いて半構造化面接の手法に従って行った.質問に対する回答は録音したうえでテキスト化し,テキストマイニングの手法によってデータ化し集計した. 顎関節症への病識としては「あごがずれる病気」,「歯のかみ合わせが悪いと起こる病気」という回答がともに4例と最も多かった.しかしそのような疾患説明を受けた患者は1例のみであった.受けた治療はマウスピースが3例で最も多かったが,その治療の必要性,実施理由の説明を受けたインフォーマントはいなかった.治療に対する満足は6名が表明したが,不満との回答も2例みられた.PQの構成においては雑音,開口障害,疼痛に対して,提示した治療法では開口練習,マッサージ,湿布が最も多く,安静,整体,マウスピースが続いた. この面接調査により,インフォーマントがもつ病態や治療法に対する知識は全般的に少ないことが明らかになった.この原因として歯科担当医による病態や治療の説明がほとんどなされていないことが考えられた."},"publication_date":"2010-12-20","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.22","number":"No.3","starting_page":"151","ending_page":"157","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11246/gakukansetsu.22.151"],"issn":["0915-3004"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:137, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/20859553","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249638","label":"url"}],"paper_title":{"en":"A 15-year clinical comparative study of the cumulative survival rate of cast metal core and resin core restorations luted with adhesive resin cement.","ja":"A 15-year clinical comparative study of the cumulative survival rate of cast metal core and resin core restorations luted with adhesive resin cement."},"authors":{"en":[{"name":"Hikasa Takayuki"},{"name":"Matsuka Yoshizo"},{"name":"Mine Atsushi"},{"name":"Minakuchi Hajime"},{"name":"Hara Emilio Satoshi"},{"name":"Van Meerbeek Bart"},{"name":"Yatani Hirofumi"},{"name":"Kuboki Takuo"}],"ja":[{"name":"Hikasa Takayuki"},{"name":"松香 芳三"},{"name":"Mine Atsushi"},{"name":"Minakuchi Hajime"},{"name":"Hara Emilio Satoshi"},{"name":"Van Meerbeek Bart"},{"name":"Yatani Hirofumi"},{"name":"Kuboki Takuo"}]},"description":{"en":"Cast metal cores were associated with a significantly lower CSR than resin cores, and significant risk factors for core failure were sex (male), absence of remaining coronal dentin, core restoration type (cast metal), and higher age at core insertion.","ja":"Cast metal cores were associated with a significantly lower CSR than resin cores, and significant risk factors for core failure were sex (male), absence of remaining coronal dentin, core restoration type (cast metal), and higher age at core insertion."},"publication_date":"2010-10","publication_name":{"en":"The International Journal of Prosthodontics","ja":"The International Journal of Prosthodontics"},"volume":"Vol.23","number":"No.5","starting_page":"397","ending_page":"405","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0022-3913(11)60030-9"],"issn":["0893-2174"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:138, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10026405887/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1571135651025476608/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250014","label":"url"}],"paper_title":{"en":"GRADEシステムによる顎関節症初期診療ガイドラインの作成","ja":"GRADEシステムによる顎関節症初期診療ガイドラインの作成"},"authors":{"en":[{"name":"覚道 健治"},{"name":"木野 孔司"},{"name":"杉崎 正志"},{"name":"湯浅 秀道"},{"name":"Matsuka Yoshizo"},{"name":"齋藤 高"},{"name":"星 佳芳"}],"ja":[{"name":"覚道 健治"},{"name":"木野 孔司"},{"name":"杉崎 正志"},{"name":"湯浅 秀道"},{"name":"松香 芳三"},{"name":"齋藤 高"},{"name":"星 佳芳"}]},"publication_date":"2010-03","publication_name":{"en":"Journal of the Japanese Association for Dental Science","ja":"日本歯科医学会誌"},"volume":"Vol.29","number":"No.29","starting_page":"52","ending_page":"56","languages":["jpn"],"referee":true,"identifiers":{"issn":["0286-164X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:139, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10026405903/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1571135651364770560/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250013","label":"url"}],"paper_title":{"en":"スプリント療法ガイドラインの確立","ja":"スプリント療法ガイドラインの確立"},"authors":{"en":[{"name":"皆木 省吾"},{"name":"築山 能大"},{"name":"有馬 太郎"},{"name":"Ichikawa Tetsuo"},{"name":"窪木 拓男"},{"name":"兒玉 直紀"},{"name":"佐久間 重光"},{"name":"新谷 明喜"},{"name":"高津 匡樹"},{"name":"竹内 哲男"},{"name":"津賀 一弘"},{"name":"坪井 明人"},{"name":"中島 啓一朗"},{"name":"Nakano Masanori"},{"name":"成田 紀之"},{"name":"波多野 泰夫"},{"name":"藤澤 政紀"},{"name":"船登 雅彦"},{"name":"鱒見 進一"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"皆木 省吾"},{"name":"築山 能大"},{"name":"有馬 太郎"},{"name":"市川 哲雄"},{"name":"窪木 拓男"},{"name":"兒玉 直紀"},{"name":"佐久間 重光"},{"name":"新谷 明喜"},{"name":"高津 匡樹"},{"name":"竹内 哲男"},{"name":"津賀 一弘"},{"name":"坪井 明人"},{"name":"中島 啓一朗"},{"name":"中野 雅德"},{"name":"成田 紀之"},{"name":"波多野 泰夫"},{"name":"藤澤 政紀"},{"name":"船登 雅彦"},{"name":"鱒見 進一"},{"name":"松香 芳三"}]},"publication_date":"2010-03","publication_name":{"en":"Journal of the Japanese Association for Dental Science","ja":"日本歯科医学会誌"},"volume":"Vol.29","number":"No.29","starting_page":"62","ending_page":"66","languages":["jpn"],"referee":true,"identifiers":{"issn":["0286-164X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:140, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/20123380","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249639","label":"url"}],"paper_title":{"en":"The relationship between temporomandibular joint pathosis and muscle tenderness in the orofacial and neck/shoulder region.","ja":"The relationship between temporomandibular joint pathosis and muscle tenderness in the orofacial and neck/shoulder region."},"authors":{"en":[{"name":"Inoue Eitoku"},{"name":"Maekawa Kenji"},{"name":"Minakuchi Hajime"},{"name":"Nagamatsu-Sakaguchi Chiyomi"},{"name":"Ono Tsuyoshi"},{"name":"Matsuka Yoshizo"},{"name":"Clark GT"},{"name":"Kuboki Takuo"}],"ja":[{"name":"Inoue Eitoku"},{"name":"Maekawa Kenji"},{"name":"Minakuchi Hajime"},{"name":"Nagamatsu-Sakaguchi Chiyomi"},{"name":"Ono Tsuyoshi"},{"name":"松香 芳三"},{"name":"Clark GT"},{"name":"Kuboki Takuo"}]},"description":{"en":"These results indicated painful disk displacement to possibly be correlated with ipsilateral muscle tenderness.","ja":"These results indicated painful disk displacement to possibly be correlated with ipsilateral muscle tenderness."},"publication_date":"2010-01","publication_name":{"en":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics","ja":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics"},"volume":"Vol.109","number":"No.1","starting_page":"86","ending_page":"90","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.tripleo.2009.07.050"],"issn":["1528-395X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:141, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10026256451/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001204419736064/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250016","label":"url"}],"paper_title":{"en":"顎関節症のスプリント治療に関する実態調査 大学病院顎関節症外来および一般開業歯科医院における診療時間の比較","ja":"顎関節症のスプリント治療に関する実態調査 大学病院顎関節症外来および一般開業歯科医院における診療時間の比較"},"authors":{"en":[{"name":"兒玉 直紀"},{"name":"築山 能大"},{"name":"有馬 太郎"},{"name":"Ichikawa Tetsuo"},{"name":"窪木 拓男"},{"name":"佐久間 重光"},{"name":"新谷 明喜"},{"name":"高津 匡樹"},{"name":"津賀 一弘"},{"name":"坪井 明人"},{"name":"Nakano Masanori"},{"name":"成田 紀之"},{"name":"波多野 泰夫"},{"name":"藤澤 政紀"},{"name":"船登 雅彦"},{"name":"鱒見 進一"},{"name":"Matsuka Yoshizo"},{"name":"皆木 省吾"}],"ja":[{"name":"兒玉 直紀"},{"name":"築山 能大"},{"name":"有馬 太郎"},{"name":"市川 哲雄"},{"name":"窪木 拓男"},{"name":"佐久間 重光"},{"name":"新谷 明喜"},{"name":"高津 匡樹"},{"name":"津賀 一弘"},{"name":"坪井 明人"},{"name":"中野 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Shinya"},{"name":"Ogawa Takumi"},{"name":"Shigeta Yuko"},{"name":"Ando Eriko"},{"name":"Hirabayashi Rio"},{"name":"Ikawa Tomoko"},{"name":"Kasama Shintaro"},{"name":"Fukushima Shunji"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Hirai Shinya"},{"name":"Ogawa Takumi"},{"name":"Shigeta Yuko"},{"name":"Ando Eriko"},{"name":"Hirabayashi Rio"},{"name":"Ikawa Tomoko"},{"name":"Kasama Shintaro"},{"name":"Fukushima Shunji"},{"name":"松香 芳三"}]},"description":{"en":"Despite a sufficient lateral excursion, motion of the mandible was limited by some factors at opening and suggests that the mode of lateral movements in SQM patients may differ slightly from those in healthy individuals.","ja":"Despite a sufficient lateral excursion, motion of the mandible was limited by some factors at opening and suggests that the mode of lateral movements in SQM patients may differ slightly from those in healthy individuals."},"publication_date":"2009-11","publication_name":{"en":"Oral Surgery, Oral Medicine, Oral 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全宏"}]},"publication_date":"2009-09-30","publication_name":{"en":"Japanese Journal of Gerodontology","ja":"老年歯科医学"},"volume":"Vol.24","number":"No.2","starting_page":"104","ending_page":"116","languages":["jpn"],"referee":true,"identifiers":{"issn":["0914-3866"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:145, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797104"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10025692891/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1573950400630805888/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250021","label":"url"}],"paper_title":{"en":"三叉神経痛治療のための薬物治療法の開発","ja":"三叉神経痛治療のための薬物治療法の開発"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"北村 洋一"},{"name":"山本 由弥子"},{"name":"園山 亘"},{"name":"Spigelman Igor"},{"name":"小熊 恵二"},{"name":"窪木 拓男"}],"ja":[{"name":"松香 芳三"},{"name":"北村 洋一"},{"name":"山本 由弥子"},{"name":"園山 亘"},{"name":"Spigelman Igor"},{"name":"小熊 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Supanigar"},{"name":"Nishimura Ichiro"},{"name":"Spigelman Igor"}],"ja":[{"name":"Thakor Devang Kashyap"},{"name":"Lin Audrey"},{"name":"松香 芳三"},{"name":"Meyer Edward M"},{"name":"Ruangsri Supanigar"},{"name":"Nishimura Ichiro"},{"name":"Spigelman Igor"}]},"description":{"en":"Cuff entrapment injury resulted in significantly elevated axonal excitability and increased NaV1.8 immunoreactivity in rat sciatic nerves. The concomitant axonal accumulation of NaV1.8 mRNA may play a role in the pathogenesis of this model of neuropathic pain.","ja":"Cuff entrapment injury resulted in significantly elevated axonal excitability and increased NaV1.8 immunoreactivity in rat sciatic nerves. The concomitant axonal accumulation of NaV1.8 mRNA may play a role in the pathogenesis of this model of neuropathic pain."},"publication_date":"2009-03-25","publication_name":{"en":"Molecular Pain","ja":"Molecular Pain"},"volume":"Vol.5","starting_page":"14","ending_page":"14","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1186/1744-8069-5-14"],"issn":["1744-8069"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:147, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/19249597","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249644","label":"url"}],"paper_title":{"en":"Simvastatin induces the odontogenic differentiation of human dental pulp stem cells in vitro and in vivo.","ja":"Simvastatin induces the odontogenic differentiation of human dental pulp stem cells in vitro and in vivo."},"authors":{"en":[{"name":"Okamoto Yosuke"},{"name":"Sonoyama Wataru"},{"name":"Ono Mitsuaki"},{"name":"Akiyama Kentaro"},{"name":"Fujisawa Takuo"},{"name":"Oshima Masamitsu"},{"name":"Tsuchimoto Yohei"},{"name":"Matsuka Yoshizo"},{"name":"Yasuda Tatsuji"},{"name":"Shi Songtao"},{"name":"Kuboki Takuo"}],"ja":[{"name":"Okamoto Yosuke"},{"name":"Sonoyama Wataru"},{"name":"Ono Mitsuaki"},{"name":"Akiyama Kentaro"},{"name":"Fujisawa Takuo"},{"name":"Oshima Masamitsu"},{"name":"Tsuchimoto Yohei"},{"name":"松香 芳三"},{"name":"Yasuda Tatsuji"},{"name":"Shi Songtao"},{"name":"Kuboki Takuo"}]},"description":{"en":"Statin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, is known to promote bone formation. However, it is not clear whether statin affects the differentiation of pulp cells. This study used a cell proliferation assay, cell cycle analysis, quantitative reverse transcriptase polymerase chain reaction (RT-PCR) and in vivo transplantation to examine the effects of simvastatin on human dental pulp stem cells (DPSCs) in vitro and in vivo. Simvastatin at 1 mumol/L was able to significantly suppress the proliferation of DPSCs without inducing apoptosis. Quantitative RT-PCR revealed both osteocalcin and dentin sialophosphoprotein to be significantly up-regulated when DPSCs were cultured with simvastatin in comparison to bone morphogenetic protein-2 treatment. The in vivo transplantation data showed that simvastatin treatment promoted mineralized tissue formation. Taken together, these results suggest that statin might be an ideal active ingredient to accelerate the differentiation of DPSCs.","ja":"Statin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, is known to promote bone formation. However, it is not clear whether statin affects the differentiation of pulp cells. This study used a cell proliferation assay, cell cycle analysis, quantitative reverse transcriptase polymerase chain reaction (RT-PCR) and in vivo transplantation to examine the effects of simvastatin on human dental pulp stem cells (DPSCs) in vitro and in vivo. Simvastatin at 1 mumol/L was able to significantly suppress the proliferation of DPSCs without inducing apoptosis. Quantitative RT-PCR revealed both osteocalcin and dentin sialophosphoprotein to be significantly up-regulated when DPSCs were cultured with simvastatin in comparison to bone morphogenetic protein-2 treatment. The in vivo transplantation data showed that simvastatin treatment promoted mineralized tissue formation. Taken together, these results suggest that statin might be an ideal active ingredient to accelerate the differentiation of DPSCs."},"publication_date":"2009-03","publication_name":{"en":"Journal of Endodontics","ja":"Journal of Endodontics"},"volume":"Vol.35","number":"No.3","starting_page":"367","ending_page":"372","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.joen.2008.11.024"],"issn":["1878-3554"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:148, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/19409226","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249641","label":"url"}],"paper_title":{"en":"Botulinum toxin type a (150 kDa) decreases exaggerated neurotransmitter release from trigeminal ganglion neurons and relieves neuropathy behaviors induced by infraorbital nerve constriction.","ja":"Botulinum toxin type a (150 kDa) decreases exaggerated neurotransmitter release from trigeminal ganglion neurons and relieves neuropathy behaviors induced by infraorbital nerve constriction."},"authors":{"en":[{"name":"Kitamura Y"},{"name":"Matsuka Yoshizo"},{"name":"Spigelman I"},{"name":"Ishihara Y"},{"name":"Yamamoto Y"},{"name":"Sonoyama W"},{"name":"Kamioka H"},{"name":"Yamashiro T"},{"name":"Kuboki T"},{"name":"Oguma K"}],"ja":[{"name":"Kitamura Y"},{"name":"松香 芳三"},{"name":"Spigelman I"},{"name":"Ishihara Y"},{"name":"Yamamoto Y"},{"name":"Sonoyama W"},{"name":"Kamioka H"},{"name":"Yamashiro T"},{"name":"Kuboki T"},{"name":"Oguma K"}]},"description":{"en":"Many patients with trigeminal neuropathies suffer severe chronic pain which is inadequately alleviated with centrally-acting drugs. These drugs also possess severe side effects making compliance difficult. One strategy is to develop new treatments without central side effects by targeting peripheral sensory neurons, since sensory neuron excitability and neurotransmitter release increase in chronic pain states. Such treatments may include the highly purified botulinum toxin type A 150 kDa (BoNT/A) which reportedly blocks vesicular neurotransmitter release. We set out to determine if experimental trigeminal neuropathy induced by infraorbital nerve constriction (IoNC) in rats could alter neurotransmitter release from somata of trigeminal sensory neurons and if it could be attenuated by BoNT/A. Thus, we monitored the secretory activity of acutely dissociated trigeminal ganglion (TRG) neurons from naïve and IoNC rats by measuring the fluorescence intensity of the membrane-uptake marker (N-(3-triethylammoniumpropyl)-4-(6-(4-(diethylamino)phenyl)hexatrienyl)pyridinium dibromide (FM4-64). FM4-64 staining showed that neurons possess a pool of recycled vesicles which could be released by high KCl (75 mM) application. BoNT/A pre-treatment of acutely dissociated TRG neurons from naïve rats significantly reduced the rate of FM4-64 dye release. Neurons isolated from TRG ipsilateral to IoNC exhibited significantly faster onset of FM4-64 release than neurons contralateral to IoNC (sham surgery). IoNC also produced long-lasting ipsilateral tactile allodynia, measured as large decreases of withdrawal thresholds to mechanical stimulation. Intradermal injection of BoNT/A in the area of infraorbital branch of the trigeminal nerve (IoN) innervation alleviated IoNC-induced mechanical allodynia and reduced the exaggerated FM4-64 release in TRG neurons from these rats. Our results suggest that BoNT/A decreases neuropathic pain behaviors by decreasing the exaggerated neurotransmitter release from TRG sensory neurons.","ja":"Many patients with trigeminal neuropathies suffer severe chronic pain which is inadequately alleviated with centrally-acting drugs. These drugs also possess severe side effects making compliance difficult. One strategy is to develop new treatments without central side effects by targeting peripheral sensory neurons, since sensory neuron excitability and neurotransmitter release increase in chronic pain states. Such treatments may include the highly purified botulinum toxin type A 150 kDa (BoNT/A) which reportedly blocks vesicular neurotransmitter release. We set out to determine if experimental trigeminal neuropathy induced by infraorbital nerve constriction (IoNC) in rats could alter neurotransmitter release from somata of trigeminal sensory neurons and if it could be attenuated by BoNT/A. Thus, we monitored the secretory activity of acutely dissociated trigeminal ganglion (TRG) neurons from naïve and IoNC rats by measuring the fluorescence intensity of the membrane-uptake marker (N-(3-triethylammoniumpropyl)-4-(6-(4-(diethylamino)phenyl)hexatrienyl)pyridinium dibromide (FM4-64). FM4-64 staining showed that neurons possess a pool of recycled vesicles which could be released by high KCl (75 mM) application. BoNT/A pre-treatment of acutely dissociated TRG neurons from naïve rats significantly reduced the rate of FM4-64 dye release. Neurons isolated from TRG ipsilateral to IoNC exhibited significantly faster onset of FM4-64 release than neurons contralateral to IoNC (sham surgery). IoNC also produced long-lasting ipsilateral tactile allodynia, measured as large decreases of withdrawal thresholds to mechanical stimulation. Intradermal injection of BoNT/A in the area of infraorbital branch of the trigeminal nerve (IoN) innervation alleviated IoNC-induced mechanical allodynia and reduced the exaggerated FM4-64 release in TRG neurons from these rats. Our results suggest that BoNT/A decreases neuropathic pain behaviors by decreasing the exaggerated neurotransmitter release from TRG sensory neurons."},"publication_date":"2009-02-03","publication_name":{"en":"Neuroscience","ja":"Neuroscience"},"volume":"Vol.159","number":"No.4","starting_page":"1422","ending_page":"1429","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.neuroscience.2009.01.066"],"issn":["1873-7544"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:149, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10029764104/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282680277550592/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250020","label":"url"}],"paper_title":{"en":"Diagnosis and Management for Temporomandibular Disorders under Consideration of the Etiology : Ordinal Management for Temporomandibular Disorders","ja":"顎機能障害の診断と発症原因を考慮に入れた治療 顎機能障害に対する一般的な治療法"},"authors":{"en":[{"name":"Matsuka Yoshizo"}],"ja":[{"name":"松香 芳三"}]},"publication_date":"2009-01-10","publication_name":{"en":"Annals of Japan Prosthodontic Society","ja":"日本補綴歯科学会誌"},"volume":"Vol.1","number":"No.1","starting_page":"13","ending_page":"20","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.2186/ajps.1.13"],"issn":["1883-4426"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:150, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797109"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250019","label":"url"}],"paper_title":{"en":"歯科PBL教育の効果に対するテュータの経験度の影響","ja":"歯科PBL教育の効果に対するテュータの経験度の影響"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"礒兼 衣里"},{"name":"完山 学"},{"name":"水口 一"},{"name":"上原 淳二"},{"name":"縄稚 久美子"},{"name":"上枝 麻友"},{"name":"笈田 育尚"},{"name":"三野 卓哉"},{"name":"新川 重彦"},{"name":"前川 賢治"},{"name":"荒川 光"},{"name":"園山 亘"},{"name":"窪木 拓男"}],"ja":[{"name":"松香 芳三"},{"name":"礒兼 衣里"},{"name":"完山 学"},{"name":"水口 一"},{"name":"上原 淳二"},{"name":"縄稚 久美子"},{"name":"上枝 麻友"},{"name":"笈田 育尚"},{"name":"三野 卓哉"},{"name":"新川 重彦"},{"name":"前川 賢治"},{"name":"荒川 光"},{"name":"園山 亘"},{"name":"窪木 拓男"}]},"publication_date":"2009","publication_name":{"en":"The Journal of Okayama Dental Society","ja":"岡山歯学会雑誌"},"volume":"Vol.28","number":"No.1","starting_page":"11","ending_page":"17","languages":["jpn"],"referee":true,"identifiers":{"issn":["0913-3941"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:151, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250015","label":"url"}],"paper_title":{"en":"岡山大学歯学部戦略的計画 求められている今後の対応策","ja":"岡山大学歯学部戦略的計画 求められている今後の対応策"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"池亀 美華"},{"name":"吉田 登志子"},{"name":"有馬 太郎"},{"name":"皆木 省吾"},{"name":"山本 敏男"},{"name":"高柴 正悟"},{"name":"窪木 拓男"},{"name":"北山 滋雄"},{"name":"滝川 正春"},{"name":"松尾 龍二"}],"ja":[{"name":"松香 芳三"},{"name":"池亀 美華"},{"name":"吉田 登志子"},{"name":"有馬 太郎"},{"name":"皆木 省吾"},{"name":"山本 敏男"},{"name":"高柴 正悟"},{"name":"窪木 拓男"},{"name":"北山 滋雄"},{"name":"滝川 正春"},{"name":"松尾 龍二"}]},"publication_date":"2009","publication_name":{"en":"The Journal of Okayama Dental Society","ja":"岡山歯学会雑誌"},"volume":"Vol.28","number":"No.2","starting_page":"123","ending_page":"130","languages":["jpn"],"referee":true,"identifiers":{"issn":["0913-3941"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:152, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/19108746","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249645","label":"url"}],"paper_title":{"en":"Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats.","ja":"Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats."},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Ono Takeshi"},{"name":"Iwase Hirotate"},{"name":"Mitrirattanakul Somsak"},{"name":"Omoto Kevin S"},{"name":"Cho Ting"},{"name":"Lam Yan Yan N"},{"name":"Snyder Bradley"},{"name":"Spigelman Igor"}],"ja":[{"name":"松香 芳三"},{"name":"Ono Takeshi"},{"name":"Iwase Hirotate"},{"name":"Mitrirattanakul Somsak"},{"name":"Omoto Kevin S"},{"name":"Cho Ting"},{"name":"Lam Yan Yan N"},{"name":"Snyder Bradley"},{"name":"Spigelman Igor"}]},"description":{"en":"These data suggest that peripheral nerve entrapment increases DRG metabolism and ATP release, which in turn is modulated by increased A1R activation.","ja":"These data suggest that peripheral nerve entrapment increases DRG metabolism and ATP release, which in turn is modulated by increased A1R activation."},"publication_date":"2008-12-24","publication_name":{"en":"Molecular Pain","ja":"Molecular Pain"},"volume":"Vol.4","starting_page":"66","ending_page":"66","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1186/1744-8069-4-66"],"issn":["1744-8069"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:153, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250022","label":"url"}],"paper_title":{"en":"高齢者の歯列欠損補綴治療法に関するチュートリアル学習とその効果","ja":"高齢者の歯列欠損補綴治療法に関するチュートリアル学習とその効果"},"authors":{"en":[{"name":"前川 賢治"},{"name":"前田 あずさ"},{"name":"内部 健太"},{"name":"北村 洋一"},{"name":"暈 貴行"},{"name":"上原 淳二"},{"name":"完山 学"},{"name":"縄稚 久美子"},{"name":"荒川 光"},{"name":"藤沢 拓生"},{"name":"水口 一"},{"name":"峯 篤史"},{"name":"Matsuka Yoshizo"},{"name":"窪木 拓男"}],"ja":[{"name":"前川 賢治"},{"name":"前田 あずさ"},{"name":"内部 健太"},{"name":"北村 洋一"},{"name":"暈 貴行"},{"name":"上原 淳二"},{"name":"完山 学"},{"name":"縄稚 久美子"},{"name":"荒川 光"},{"name":"藤沢 拓生"},{"name":"水口 一"},{"name":"峯 篤史"},{"name":"松香 芳三"},{"name":"窪木 拓男"}]},"publication_date":"2008","publication_name":{"en":"The Journal of Japanese Dental Education Association","ja":"日本歯科医学教育学会雑誌"},"volume":"Vol.24","number":"No.2","starting_page":"207","ending_page":"213","languages":["jpn"],"referee":true,"identifiers":{"issn":["0914-5133"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:154, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797113"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250012","label":"url"}],"paper_title":{"en":"粘膜圧迫により疼痛の軽減がみられた三叉神経に生じた持続性ニューロパシー性疼痛の2例","ja":"粘膜圧迫により疼痛の軽減がみられた三叉神経に生じた持続性ニューロパシー性疼痛の2例"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"熊田 愛"},{"name":"前川 賢治"},{"name":"水口 一"},{"name":"窪木 拓男"}],"ja":[{"name":"松香 芳三"},{"name":"熊田 愛"},{"name":"前川 賢治"},{"name":"水口 一"},{"name":"窪木 拓男"}]},"publication_date":"2008","publication_name":{"en":"Japanese Journal of Orofacial Pain","ja":"日本口腔顔面痛学会雑誌"},"volume":"Vol.1","number":"No.1","starting_page":"55","ending_page":"59","languages":["jpn"],"referee":true,"identifiers":{"issn":["1883-308X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:155, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797114"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250004","label":"url"}],"paper_title":{"en":"専用ホームページならびにインターネット掲示板を利用した補綴スキル教育における学生・教官相互コミュニケーション","ja":"専用ホームページならびにインターネット掲示板を利用した補綴スキル教育における学生・教官相互コミュニケーション"},"authors":{"en":[{"name":"暈 貴行"},{"name":"水口 一"},{"name":"内部 健太"},{"name":"北村 洋一"},{"name":"前田 あずさ"},{"name":"永松[坂口] 千代美"},{"name":"上原 淳二"},{"name":"Matsuka Yoshizo"},{"name":"窪木 拓男"}],"ja":[{"name":"暈 貴行"},{"name":"水口 一"},{"name":"内部 健太"},{"name":"北村 洋一"},{"name":"前田 あずさ"},{"name":"永松[坂口] 千代美"},{"name":"上原 淳二"},{"name":"松香 芳三"},{"name":"窪木 拓男"}]},"publication_date":"2008","publication_name":{"en":"The Journal of Okayama Dental Society","ja":"岡山歯学会雑誌"},"volume":"Vol.27","number":"No.1","starting_page":"23","ending_page":"28","languages":["jpn"],"referee":true,"identifiers":{"issn":["0913-3941"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:156, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797115"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250001","label":"url"}],"paper_title":{"en":"EBMワークショップと大学院教育の実質化","ja":"EBMワークショップと大学院教育の実質化"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"福岡 敏雄"},{"name":"完山 学"},{"name":"前川 賢治"},{"name":"荒川 光"},{"name":"水口 一"},{"name":"園山 亘"},{"name":"上原 淳二"},{"name":"縄稚 久美子"},{"name":"山崎 聖也"},{"name":"窪木 拓男"},{"name":"滝川 正春"},{"name":"松尾 龍二"},{"name":"田中 紀章"}],"ja":[{"name":"松香 芳三"},{"name":"福岡 敏雄"},{"name":"完山 学"},{"name":"前川 賢治"},{"name":"荒川 光"},{"name":"水口 一"},{"name":"園山 亘"},{"name":"上原 淳二"},{"name":"縄稚 久美子"},{"name":"山崎 聖也"},{"name":"窪木 拓男"},{"name":"滝川 正春"},{"name":"松尾 龍二"},{"name":"田中 紀章"}]},"publication_date":"2008","publication_name":{"en":"The Journal of Okayama Dental Society","ja":"岡山歯学会雑誌"},"volume":"Vol.27","number":"No.1","starting_page":"43","ending_page":"49","languages":["jpn"],"referee":true,"identifiers":{"issn":["0913-3941"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:157, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10019489174/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282679397872768/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250007","label":"url"}],"paper_title":{"en":"保存療法が有効ではなかった非復位性顎関節円板前方転位症例の臨床所見ならびにMRI所見の検討","ja":"保存療法が有効ではなかった非復位性顎関節円板前方転位症例の臨床所見ならびにMRI所見の検討"},"authors":{"en":[{"name":"岩瀬 博建"},{"name":"佐々木 忠昭"},{"name":"麻野 和宏"},{"name":"Matsuka Yoshizo"},{"name":"マイトリラタナクル サムサック"},{"name":"今井 裕"}],"ja":[{"name":"岩瀬 博建"},{"name":"佐々木 忠昭"},{"name":"麻野 和宏"},{"name":"松香 芳三"},{"name":"マイトリラタナクル サムサック"},{"name":"今井 裕"}]},"publication_date":"2007-04-20","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.19","number":"No.1","starting_page":"32","ending_page":"35","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11246/gakukansetsu1989.19.32"],"issn":["0915-3004"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:158, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/17386072","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249646","label":"url"}],"paper_title":{"en":"Bidirectional alterations of hippocampal cannabinoid 1 receptors and their endogenous ligands in a rat model of alcohol withdrawal and dependence.","ja":"Bidirectional alterations of hippocampal cannabinoid 1 receptors and their endogenous ligands in a rat model of alcohol withdrawal and dependence."},"authors":{"en":[{"name":"Mitrirattanakul Somsak"},{"name":"López-Valdés Héctor E"},{"name":"Liang Jing"},{"name":"Matsuka Yoshizo"},{"name":"Mackie Ken"},{"name":"Faull Kym F"},{"name":"Spigelman Igor"}],"ja":[{"name":"Mitrirattanakul Somsak"},{"name":"López-Valdés Héctor E"},{"name":"Liang Jing"},{"name":"松香 芳三"},{"name":"Mackie Ken"},{"name":"Faull Kym F"},{"name":"Spigelman Igor"}]},"description":{"en":"These data demonstrate that CIE treatment and withdrawal transiently down-regulates hippocampal CB1 Rs followed by a long-term up-regulation, including increased levels of endogenous cannabinoids. These findings are consistent with our hypothesis and suggest that long-term up-regulation of hippocampal CB1Rs may contribute to the long-term cognitive impairments in alcoholism. The data further suggest that the effectiveness of CB1R blockade in decreasing alcohol consumption may be greater after protracted abstinence from alcohol.","ja":"These data demonstrate that CIE treatment and withdrawal transiently down-regulates hippocampal CB1 Rs followed by a long-term up-regulation, including increased levels of endogenous cannabinoids. These findings are consistent with our hypothesis and suggest that long-term up-regulation of hippocampal CB1Rs may contribute to the long-term cognitive impairments in alcoholism. The data further suggest that the effectiveness of CB1R blockade in decreasing alcohol consumption may be greater after protracted abstinence from alcohol."},"publication_date":"2007-03-26","publication_name":{"en":"Alcoholism, Clinical and Experimental Research","ja":"Alcoholism, Clinical and Experimental Research"},"volume":"Vol.31","number":"No.5","starting_page":"855","ending_page":"867","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1111/j.1530-0277.2007.00366.x"],"issn":["0145-6008"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:159, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/17321484","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249647","label":"url"}],"paper_title":{"en":"Responses of the hypothalamic-pituitary-adrenal axis and pain threshold changes in the orofacial region upon cold pressor stimulation in normal volunteers.","ja":"Responses of the hypothalamic-pituitary-adrenal axis and pain threshold changes in the orofacial region upon cold pressor stimulation in normal volunteers."},"authors":{"en":[{"name":"Suzuki Koji"},{"name":"Maekawa Kenji"},{"name":"Minakuchi Hajime"},{"name":"Yatani Hirofumi"},{"name":"Clark Glenn T"},{"name":"Matsuka Yoshizo"},{"name":"Kuboki Takuo"}],"ja":[{"name":"Suzuki Koji"},{"name":"Maekawa Kenji"},{"name":"Minakuchi Hajime"},{"name":"Yatani Hirofumi"},{"name":"Clark Glenn T"},{"name":"松香 芳三"},{"name":"Kuboki Takuo"}]},"description":{"en":"This observed pain threshold increase might be due to the activation of an endogenous opioid system, such as increase in the circulating beta-endorphin levels.","ja":"This observed pain threshold increase might be due to the activation of an endogenous opioid system, such as increase in the circulating beta-endorphin levels."},"publication_date":"2007-02-26","publication_name":{"en":"Archives of Oral Biology","ja":"Archives of Oral Biology"},"volume":"Vol.52","number":"No.8","starting_page":"797","ending_page":"802","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.archoralbio.2007.01.008"],"issn":["0003-9969"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:160, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/17304914","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249648","label":"url"}],"paper_title":{"en":"Comparison of inter-twin concordance in symptoms of temporomandibular disorders: a preliminary investigation in an adolescent twin population.","ja":"Comparison of inter-twin concordance in symptoms of temporomandibular disorders: a preliminary investigation in an adolescent twin population."},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Nagamatsu Chiyomi"},{"name":"Itoh Shingo"},{"name":"Tomonari Takayuki"},{"name":"Makki Ali"},{"name":"Minakuchi Hajime"},{"name":"Maekawa Kenji"},{"name":"Kanyama Manabu"},{"name":"Kuboki Takuo"}],"ja":[{"name":"松香 芳三"},{"name":"Nagamatsu Chiyomi"},{"name":"Itoh Shingo"},{"name":"Tomonari Takayuki"},{"name":"Makki Ali"},{"name":"Minakuchi Hajime"},{"name":"Maekawa Kenji"},{"name":"Kanyama Manabu"},{"name":"Kuboki Takuo"}]},"description":{"en":"There is controversy as to the genetic contribution to the pathogenesis of temporo-mandibular disorders (TMD). Several reports reveal a marked familial aggregation in the signs and symptoms of TMD, while others do not. Therefore, our goal was to investigate the hypothesis using a sophisticated research design, which was a well-known genetic survey inter-twin concordance assessment in the symptoms of TMD. This study is the first step to survey TMD symptoms of a twin group in junior and high schools as a preliminary trial. The 63 twins were asked to participate in this study in junior and senior high schools affiliated with the University of Tokyo, Japan, schools which kept ten twins in each grade for the purpose of several genetic survey programs. After excluding incomplete filling out of questionnaire sheets and data from male-female pairs, 43 monozygotic (MZ) (15.3+/-1.7 yrs, male/female = 17/26 pairs) and nine dyzygotic (DZ) (15.2+/-1.8 yrs, male/female = 6/3 pairs) twins were studied. Outcomes consisted of a prevalidated 14-item self-administered questionnaire, which assessed proband- and pair-wise concordance levels in the MZ and DZ twins. These results demonstrated that the MZ twins had a higher tendency of inter-twin concordance than DZ twins in terms of jaw pain in wide mouth opening (proband-wise concordance = 66.7% in MZ, 0% in DZ), difficulty in mouth opening (20% in MZ, 0% in DZ) and difficulty in mouth closing (50.0% in MZ, 33.3% in DZ), while there was no significant difference between the MZ and DZ concordance levels in other general health-related and behavior-related items, except toothache. However, the pair-wise concordance rates of jaw pain in wide mouth opening and difficulty in mouth opening in the MZ twins were not significantly higher compared to the DZ rate. Possibly, a genetic factor contributed to the pathogenesis of TMD in an adolescent population. The sample size needs to be increased, and there are plans to survey the next sample in the same schools.","ja":"There is controversy as to the genetic contribution to the pathogenesis of temporo-mandibular disorders (TMD). Several reports reveal a marked familial aggregation in the signs and symptoms of TMD, while others do not. Therefore, our goal was to investigate the hypothesis using a sophisticated research design, which was a well-known genetic survey inter-twin concordance assessment in the symptoms of TMD. This study is the first step to survey TMD symptoms of a twin group in junior and high schools as a preliminary trial. The 63 twins were asked to participate in this study in junior and senior high schools affiliated with the University of Tokyo, Japan, schools which kept ten twins in each grade for the purpose of several genetic survey programs. After excluding incomplete filling out of questionnaire sheets and data from male-female pairs, 43 monozygotic (MZ) (15.3+/-1.7 yrs, male/female = 17/26 pairs) and nine dyzygotic (DZ) (15.2+/-1.8 yrs, male/female = 6/3 pairs) twins were studied. Outcomes consisted of a prevalidated 14-item self-administered questionnaire, which assessed proband- and pair-wise concordance levels in the MZ and DZ twins. These results demonstrated that the MZ twins had a higher tendency of inter-twin concordance than DZ twins in terms of jaw pain in wide mouth opening (proband-wise concordance = 66.7% in MZ, 0% in DZ), difficulty in mouth opening (20% in MZ, 0% in DZ) and difficulty in mouth closing (50.0% in MZ, 33.3% in DZ), while there was no significant difference between the MZ and DZ concordance levels in other general health-related and behavior-related items, except toothache. However, the pair-wise concordance rates of jaw pain in wide mouth opening and difficulty in mouth opening in the MZ twins were not significantly higher compared to the DZ rate. Possibly, a genetic factor contributed to the pathogenesis of TMD in an adolescent population. The sample size needs to be increased, and there are plans to survey the next sample in the same schools."},"publication_date":"2007-01","publication_name":{"en":"Cranio","ja":"Cranio"},"volume":"Vol.25","number":"No.1","starting_page":"23","ending_page":"29","languages":["eng"],"referee":true,"identifiers":{"issn":["0886-9634"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:161, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797120"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250006","label":"url"}],"paper_title":{"en":"岡山大学歯学部5年次生に対する口腔インプラント実習の試み","ja":"岡山大学歯学部5年次生に対する口腔インプラント実習の試み"},"authors":{"en":[{"name":"完山 学"},{"name":"荒川 光"},{"name":"園山 亘"},{"name":"北村 洋一"},{"name":"木村 彩"},{"name":"野田 欣志"},{"name":"川上 彩"},{"name":"Matsuka Yoshizo"},{"name":"窪木 拓男"}],"ja":[{"name":"完山 学"},{"name":"荒川 光"},{"name":"園山 亘"},{"name":"北村 洋一"},{"name":"木村 彩"},{"name":"野田 欣志"},{"name":"川上 彩"},{"name":"松香 芳三"},{"name":"窪木 拓男"}]},"publication_date":"2007","publication_name":{"en":"The Journal of Okayama Dental Society","ja":"岡山歯学会雑誌"},"volume":"Vol.26","number":"No.2","starting_page":"119","ending_page":"124","languages":["jpn"],"referee":true,"identifiers":{"issn":["0913-3941"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:162, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/17101230","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249864","label":"url"}],"paper_title":{"en":"Two types of neurotransmitter release patterns in isolectin B4-positive and negative trigeminal ganglion neurons.","ja":"Two types of neurotransmitter release patterns in isolectin B4-positive and negative trigeminal ganglion neurons."},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Edmonds B"},{"name":"Mitrirattanakul S"},{"name":"Schweizer F E"},{"name":"Spigelman I"}],"ja":[{"name":"松香 芳三"},{"name":"Edmonds B"},{"name":"Mitrirattanakul S"},{"name":"Schweizer F E"},{"name":"Spigelman I"}]},"description":{"en":"Mammalian nociceptors have been classified into subclasses based on differential neurotrophin sensitivity and binding of the plant isolectin B4 (IB4). Most of the nerve growth factor-responsive IB4-negative (IB4 (-)) nociceptors contain neuropeptides such as substance P and calcitonin gene-related peptide, whereas the glial-derived neurotrophic factor-responsive IB4-positive (IB4 (+)) neurons predominantly lack such neuropeptides. We hypothesized that the differences in neuropeptide content between IB4 (+) and (-) neurons might be reflected in differences in stimulated exocytosis and/or endocytosis. To address this, we monitored the secretory activity of acutely dissociated neurons from adult rat trigeminal ganglia (TRG) using cell membrane capacitance (Cm) measurements and the fluorescent membrane-uptake marker N-(3-triethylammoniumpropyl)-4-(6-(4-(diethylamino)phenyl)hexatrienyl)pyridinium dibromide (FM4-64). Cm measurements were performed under whole-cell voltage clamp and neurons were depolarized from -75 mV to +10 mV to elicit exocytosis. Both types of TRG neurons showed similarly-sized, calcium-dependent increases in Cm, demonstrating that both IB4 (+) and (-) TRG neurons are capable of stimulated exocytosis. However, the peak Cm of IB4 (+) neurons decayed faster toward baseline than that of IB4 (-) neurons. Also, IB4 (+) neurons had stable Cm responses to repeated stimuli whereas IB4 (-) neurons loss their secretory response during repeated stimulation. These data suggested that the IB4 (+) neurons possess a faster rate of endocytosis and vesicle replenishment than IB4 (-) neurons. To test this, we measured vesicle trafficking with the fluorescent membrane dye FM4-64. FM4-64 staining showed that IB4 (-) neurons exhibit a larger pool of endocytosed vesicles than IB4 (+) neurons because the peak fluorescence increases in IB4 (-) neurons were larger but slower than in IB4 (+) neurons. However, the recycled vesicles were released faster in IB4 (+) compared with IB4 (-) neurons. Taken together these data suggest that the IB4 (+) TRG neurons have faster exocytosis and endocytosis than the IB4 (-) neurons.","ja":"Mammalian nociceptors have been classified into subclasses based on differential neurotrophin sensitivity and binding of the plant isolectin B4 (IB4). Most of the nerve growth factor-responsive IB4-negative (IB4 (-)) nociceptors contain neuropeptides such as substance P and calcitonin gene-related peptide, whereas the glial-derived neurotrophic factor-responsive IB4-positive (IB4 (+)) neurons predominantly lack such neuropeptides. We hypothesized that the differences in neuropeptide content between IB4 (+) and (-) neurons might be reflected in differences in stimulated exocytosis and/or endocytosis. To address this, we monitored the secretory activity of acutely dissociated neurons from adult rat trigeminal ganglia (TRG) using cell membrane capacitance (Cm) measurements and the fluorescent membrane-uptake marker N-(3-triethylammoniumpropyl)-4-(6-(4-(diethylamino)phenyl)hexatrienyl)pyridinium dibromide (FM4-64). Cm measurements were performed under whole-cell voltage clamp and neurons were depolarized from -75 mV to +10 mV to elicit exocytosis. Both types of TRG neurons showed similarly-sized, calcium-dependent increases in Cm, demonstrating that both IB4 (+) and (-) TRG neurons are capable of stimulated exocytosis. However, the peak Cm of IB4 (+) neurons decayed faster toward baseline than that of IB4 (-) neurons. Also, IB4 (+) neurons had stable Cm responses to repeated stimuli whereas IB4 (-) neurons loss their secretory response during repeated stimulation. These data suggested that the IB4 (+) neurons possess a faster rate of endocytosis and vesicle replenishment than IB4 (-) neurons. To test this, we measured vesicle trafficking with the fluorescent membrane dye FM4-64. FM4-64 staining showed that IB4 (-) neurons exhibit a larger pool of endocytosed vesicles than IB4 (+) neurons because the peak fluorescence increases in IB4 (-) neurons were larger but slower than in IB4 (+) neurons. However, the recycled vesicles were released faster in IB4 (+) compared with IB4 (-) neurons. Taken together these data suggest that the IB4 (+) TRG neurons have faster exocytosis and endocytosis than the IB4 (-) neurons."},"publication_date":"2006-11-13","publication_name":{"en":"Neuroscience","ja":"Neuroscience"},"volume":"Vol.144","number":"No.2","starting_page":"665","ending_page":"674","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.neuroscience.2006.09.053"],"issn":["0306-4522"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:163, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/16844297","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249865","label":"url"}],"paper_title":{"en":"Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain.","ja":"Site-specific increases in peripheral cannabinoid receptors and their endogenous ligands in a model of neuropathic pain."},"authors":{"en":[{"name":"Mitrirattanakul Somsak"},{"name":"Ramakul Navapoln"},{"name":"Guerrero Andre V"},{"name":"Matsuka Yoshizo"},{"name":"Ono Takeshi"},{"name":"Iwase Hirotate"},{"name":"Mackie Ken"},{"name":"Faull Kym F"},{"name":"Spigelman Igor"}],"ja":[{"name":"Mitrirattanakul Somsak"},{"name":"Ramakul Navapoln"},{"name":"Guerrero Andre V"},{"name":"松香 芳三"},{"name":"Ono Takeshi"},{"name":"Iwase Hirotate"},{"name":"Mackie Ken"},{"name":"Faull Kym F"},{"name":"Spigelman Igor"}]},"description":{"en":"Selective activation of the peripheral cannabinoid receptor 1 (CB1R) has been shown to suppress neuropathic pain symptoms in rodents. However, relatively little is known about changes in CB1R and its endogenous ligands during development or maintenance of neuropathic pain. Using immunohistochemistry, Western blot, real-time reverse transcription polymerase chain reaction, as well as liquid chromatography/mass spectrometry, we studied the changes in CB1Rs and endocannabinoids N-arachidonoylethanolamine/anandamide (AEA) and 2-arachidonoylglycerol (2-AG) in rat lumbar (L4 and L5) dorsal root ganglia (DRG) after neuropathic pain induction (L5 spinal nerve ligation: SNL). Immunohistochemistry revealed that in control rats, CB1R is expressed in the majority (76-83%) of nociceptive neurons as indicated by co-labeling with isolectin B4 (IB4) or antibodies recognizing transient receptor potential vanilloid (TRPV1), calcitonin gene related peptide (CGRP), and the NR2C/2D subunits of the N-methyl-D-aspartate receptor. After L5 SNL, CB1R mRNA and protein increases in the ipsilateral uninjured L4 DRG whereas the percentages of CB1R immunoreactive (CB1R-ir) neurons remain unchanged in L4 and L5 DRG. However, for these CB1R-ir neurons, we observe significant increases in percentage of TRPV1-ir cells in ipsilateral L4 DRG, and decreases in percentage of IB4- and CGRP-co-labeled cells in ipsilateral L5 DRG. Levels of both AEA and 2-AG increase significantly only in the ipsilateral L5 DRG. These results are consistent with the preserved analgesic effects of cannabinoids in neuropathic pain and provide a rational framework for the development of peripherally acting endocannabinoid-based therapeutic interventions for neuropathic pain.","ja":"Selective activation of the peripheral cannabinoid receptor 1 (CB1R) has been shown to suppress neuropathic pain symptoms in rodents. However, relatively little is known about changes in CB1R and its endogenous ligands during development or maintenance of neuropathic pain. Using immunohistochemistry, Western blot, real-time reverse transcription polymerase chain reaction, as well as liquid chromatography/mass spectrometry, we studied the changes in CB1Rs and endocannabinoids N-arachidonoylethanolamine/anandamide (AEA) and 2-arachidonoylglycerol (2-AG) in rat lumbar (L4 and L5) dorsal root ganglia (DRG) after neuropathic pain induction (L5 spinal nerve ligation: SNL). Immunohistochemistry revealed that in control rats, CB1R is expressed in the majority (76-83%) of nociceptive neurons as indicated by co-labeling with isolectin B4 (IB4) or antibodies recognizing transient receptor potential vanilloid (TRPV1), calcitonin gene related peptide (CGRP), and the NR2C/2D subunits of the N-methyl-D-aspartate receptor. After L5 SNL, CB1R mRNA and protein increases in the ipsilateral uninjured L4 DRG whereas the percentages of CB1R immunoreactive (CB1R-ir) neurons remain unchanged in L4 and L5 DRG. However, for these CB1R-ir neurons, we observe significant increases in percentage of TRPV1-ir cells in ipsilateral L4 DRG, and decreases in percentage of IB4- and CGRP-co-labeled cells in ipsilateral L5 DRG. Levels of both AEA and 2-AG increase significantly only in the ipsilateral L5 DRG. These results are consistent with the preserved analgesic effects of cannabinoids in neuropathic pain and provide a rational framework for the development of peripherally acting endocannabinoid-based therapeutic interventions for neuropathic pain."},"publication_date":"2006-07-14","publication_name":{"en":"Pain","ja":"Pain"},"volume":"Vol.126","number":"No.1-3","starting_page":"102","ending_page":"114","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.pain.2006.06.016"],"issn":["1872-6623"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:164, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/16427624","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-32644433171&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249866","label":"url"}],"paper_title":{"en":"HSV-1-mediated NGF delivery delays nociceptive deficits in a genetic model of diabetic neuropathy.","ja":"HSV-1-mediated NGF delivery delays nociceptive deficits in a genetic model of diabetic neuropathy."},"authors":{"en":[{"name":"Walwyn W M"},{"name":"Matsuka Yoshizo"},{"name":"Arai D"},{"name":"Bloom D C"},{"name":"Lam H"},{"name":"Tran C"},{"name":"Spigelman I"},{"name":"Maidment N T"}],"ja":[{"name":"Walwyn W M"},{"name":"松香 芳三"},{"name":"Arai D"},{"name":"Bloom D C"},{"name":"Lam H"},{"name":"Tran C"},{"name":"Spigelman I"},{"name":"Maidment N T"}]},"description":{"en":"A previous phase III clinical trial failed to show significant therapeutic benefit of repeated subcutaneous nerve growth factor (NGF) administration in the treatment of diabetic neuropathy. Animal studies have since shown that site-specific viral-mediated expression of NGF in the lumbar dorsal root ganglia prevents peripheral nerve dysfunction associated with chemically induced neuropathy. Using a Herpes simplex virus expression vector, we have investigated the effect of localized NGF expression in a genetic mouse model of progressive diabetic neuropathy, the +/+ Leprdb mouse. We found that site-specific delivery of NGF initially delayed the appearance of hypoalgesia, assessed by the Hargreaves test, by 1 month and effectively attenuated this deficit for 2 months over the approximately 10 months normal life-span of these animals. Once the disease progressed into its more severe stages, NGF, although still capable of altering the electrophysiological profile of the sensory A- and C-fibers and influencing the expression of p75 and substance P in the dorsal root ganglia, could no longer maintain normal nociception. These data suggest that maximal therapeutic benefit in future NGF-based gene therapy trials will be gained from early applications of such viral-mediated neurotrophin delivery.","ja":"A previous phase III clinical trial failed to show significant therapeutic benefit of repeated subcutaneous nerve growth factor (NGF) administration in the treatment of diabetic neuropathy. Animal studies have since shown that site-specific viral-mediated expression of NGF in the lumbar dorsal root ganglia prevents peripheral nerve dysfunction associated with chemically induced neuropathy. Using a Herpes simplex virus expression vector, we have investigated the effect of localized NGF expression in a genetic mouse model of progressive diabetic neuropathy, the +/+ Leprdb mouse. We found that site-specific delivery of NGF initially delayed the appearance of hypoalgesia, assessed by the Hargreaves test, by 1 month and effectively attenuated this deficit for 2 months over the approximately 10 months normal life-span of these animals. Once the disease progressed into its more severe stages, NGF, although still capable of altering the electrophysiological profile of the sensory A- and C-fibers and influencing the expression of p75 and substance P in the dorsal root ganglia, could no longer maintain normal nociception. These data suggest that maximal therapeutic benefit in future NGF-based gene therapy trials will be gained from early applications of such viral-mediated neurotrophin delivery."},"publication_date":"2006-01-20","publication_name":{"en":"Experimental Neurology","ja":"Experimental Neurology"},"volume":"Vol.198","number":"No.1","starting_page":"260","ending_page":"270","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.expneurol.2005.12.006"],"issn":["0014-4886"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:165, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250008","label":"url"}],"paper_title":{"en":"岡山大学歯学部戦略的計画 教育に関する提案 岡山大学歯学部の理想的な将来のために","ja":"岡山大学歯学部戦略的計画 教育に関する提案 岡山大学歯学部の理想的な将来のために"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"池亀 美華"},{"name":"有馬 太郎"},{"name":"出口 徹"},{"name":"志茂 剛"},{"name":"松尾 龍二"},{"name":"高柴 正悟"},{"name":"渡邊 達夫"}],"ja":[{"name":"松香 芳三"},{"name":"池亀 美華"},{"name":"有馬 太郎"},{"name":"出口 徹"},{"name":"志茂 剛"},{"name":"松尾 龍二"},{"name":"高柴 正悟"},{"name":"渡邊 達夫"}]},"publication_date":"2006","publication_name":{"en":"The Journal of Okayama Dental Society","ja":"岡山歯学会雑誌"},"volume":"Vol.25","number":"No.2","starting_page":"19","ending_page":"32","languages":["jpn"],"referee":true,"identifiers":{"issn":["0913-3941"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:166, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/16094578","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249867","label":"url"}],"paper_title":{"en":"Characterization of patients with disc displacement without reduction unresponsive to nonsurgical treatment: a preliminary study.","ja":"Characterization of patients with disc displacement without reduction unresponsive to nonsurgical treatment: a preliminary study."},"authors":{"en":[{"name":"Iwase Hirotate"},{"name":"Sasaki Tadaaki"},{"name":"Asakura Setsuko"},{"name":"Asano Kazuhiro"},{"name":"Mitrirattanakul Somsak"},{"name":"Matsuka Yoshizo"},{"name":"Imai Yutaka"}],"ja":[{"name":"Iwase Hirotate"},{"name":"Sasaki Tadaaki"},{"name":"Asakura Setsuko"},{"name":"Asano Kazuhiro"},{"name":"Mitrirattanakul Somsak"},{"name":"松香 芳三"},{"name":"Imai Yutaka"}]},"description":{"en":"Nonresponders can be characterized by their pretreatment pain-free mouth opening (<30 mm) in combination with MRI confirmation of \"stuck\" disc and unchanged disc shapes during mouth opening.","ja":"Nonresponders can be characterized by their pretreatment pain-free mouth opening (<30 mm) in combination with MRI confirmation of \"stuck\" disc and unchanged disc shapes during mouth opening."},"publication_date":"2005-08","publication_name":{"en":"Journal of Oral and Maxillofacial Surgery","ja":"Journal of Oral and Maxillofacial Surgery"},"volume":"Vol.63","number":"No.8","starting_page":"1115","ending_page":"1122","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.joms.2005.04.005"],"issn":["0278-2391"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:167, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/15855172","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249869","label":"url"}],"paper_title":{"en":"Neuronal differentiation of bone marrow-derived stromal stem cells involves suppression of discordant phenotypes through gene silencing.","ja":"Neuronal differentiation of bone marrow-derived stromal stem cells involves suppression of discordant phenotypes through gene silencing."},"authors":{"en":[{"name":"Egusa Hiroshi"},{"name":"Schweizer Felix E"},{"name":"Wang Chia-Chien"},{"name":"Matsuka Yoshizo"},{"name":"Nishimura Ichiro"}],"ja":[{"name":"Egusa Hiroshi"},{"name":"Schweizer Felix E"},{"name":"Wang Chia-Chien"},{"name":"松香 芳三"},{"name":"Nishimura Ichiro"}]},"description":{"en":"Tissue engineering involves the construction of transplantable tissues in which bone marrow aspirates may serve as an accessible source of autogenous multipotential mesenchymal stem cells. Increasing reports indicate that the lineage restriction of adult mesenchymal stem cells may be less established than previously believed, and stem cell-based therapeutics await the establishment of an efficient protocol capable of achieving a prescribed phenotype differentiation. We have investigated how adult mouse bone marrow-derived stromal cells (BMSCs) are guided to neurogenic and osteogenic phenotypes. Naïve BMSCs were found surprisingly active in expression of a wide range of mRNAs and proteins, including those normally reported in terminally differentiated neuronal cells and osteoblasts. The naïve BMSCs were found to exhibit voltage-dependent membrane currents similar to the neuronally guided BMSCs, although with smaller amplitudes. Once BMSCs were exposed to the osteogenic culture condition, the neuronal characteristics quickly disappeared. Our data suggest that the loss of discordant phenotypes during BMSC differentiation cannot be explained by the selection and elimination of unfit cells from the whole BMSC population. The percent ratio of live to dead BMSCs examined did not change during the first 8-10 days in either neurogenic or osteogenic differentiation media, and cell detachment was estimated at <1%. However, during this period, bone-associated extracellular matrix genes were selectively down-regulated in neuronally guided BMSCs. These data indicate that the suppression of discordant phenotypes of differentiating adult stem cells is achieved, at least in part, by silencing of superfluous gene clusters.","ja":"Tissue engineering involves the construction of transplantable tissues in which bone marrow aspirates may serve as an accessible source of autogenous multipotential mesenchymal stem cells. Increasing reports indicate that the lineage restriction of adult mesenchymal stem cells may be less established than previously believed, and stem cell-based therapeutics await the establishment of an efficient protocol capable of achieving a prescribed phenotype differentiation. We have investigated how adult mouse bone marrow-derived stromal cells (BMSCs) are guided to neurogenic and osteogenic phenotypes. Naïve BMSCs were found surprisingly active in expression of a wide range of mRNAs and proteins, including those normally reported in terminally differentiated neuronal cells and osteoblasts. The naïve BMSCs were found to exhibit voltage-dependent membrane currents similar to the neuronally guided BMSCs, although with smaller amplitudes. Once BMSCs were exposed to the osteogenic culture condition, the neuronal characteristics quickly disappeared. Our data suggest that the loss of discordant phenotypes during BMSC differentiation cannot be explained by the selection and elimination of unfit cells from the whole BMSC population. The percent ratio of live to dead BMSCs examined did not change during the first 8-10 days in either neurogenic or osteogenic differentiation media, and cell detachment was estimated at <1%. However, during this period, bone-associated extracellular matrix genes were selectively down-regulated in neuronally guided BMSCs. These data indicate that the suppression of discordant phenotypes of differentiating adult stem cells is achieved, at least in part, by silencing of superfluous gene clusters."},"publication_date":"2005-04-25","publication_name":{"en":"The Journal of Biological Chemistry","ja":"The Journal of Biological Chemistry"},"volume":"Vol.280","number":"No.25","starting_page":"23691","ending_page":"23697","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1074/jbc.M413796200"],"issn":["0021-9258"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:168, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10015525036/","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/15858333","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282679388620544/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250027","label":"url"}],"paper_title":{"en":"Improvement of Chewing Ability by Complete Denture : A Case Report","ja":"全部床義歯による咀嚼障害の改善"},"authors":{"en":[{"name":"Matsuka Yoshizo"}],"ja":[{"name":"松香 芳三"}]},"description":{"en":"Patient: A 58 year-old female patient visited the clinic with chief complaint of chewing difficulty with her complete dentures. These dentures did not have a sufficient size of denture base and the resin teeth were completely ground down. Treatment dentures were inserted and the form was transferred to final dentures.
Discussion: The risk of re-treatment and adjustment after the denture insertion was reduced by using the treatment dentures. The Cochrane Library reported that there is no difference between complete dentures and implant supported over dentures in terms of patient satisfaction/chewing ability, provided the patient has an adequate mandibular ridge.
Conclusion: Treatment dentures are important to reduce the risk of re-treatment.","ja":"Patient: A 58 year-old female patient visited the clinic with chief complaint of chewing difficulty with her complete dentures. These dentures did not have a sufficient size of denture base and the resin teeth were completely ground down. Treatment dentures were inserted and the form was transferred to final dentures.
Discussion: The risk of re-treatment and adjustment after the denture insertion was reduced by using the treatment dentures. The Cochrane Library reported that there is no difference between complete dentures and implant supported over dentures in terms of patient satisfaction/chewing ability, provided the patient has an adequate mandibular ridge.
Conclusion: Treatment dentures are important to reduce the risk of re-treatment."},"publication_date":"2005-04-10","publication_name":{"en":"The Journal of the Japan Prosthodontic Society","ja":"日本補綴歯科学会雑誌"},"volume":"Vol.49","number":"No.2","starting_page":"326","ending_page":"329","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.2186/jjps.49.326"],"issn":["0389-5386"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:169, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250025","label":"url"}],"paper_title":{"en":"非歯原性歯痛の発症頻度およびその内容","ja":"非歯原性歯痛の発症頻度およびその内容"},"authors":{"en":[{"name":"重田 優子"},{"name":"小川 匠"},{"name":"Matsuka Yoshizo"},{"name":"安藤 栄里子"},{"name":"深川 菜穂"},{"name":"山崎 泰志"},{"name":"豊田 長隆"},{"name":"福島 俊士"}],"ja":[{"name":"重田 優子"},{"name":"小川 匠"},{"name":"松香 芳三"},{"name":"安藤 栄里子"},{"name":"深川 菜穂"},{"name":"山崎 泰志"},{"name":"豊田 長隆"},{"name":"福島 俊士"}]},"publication_date":"2005","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.17","number":"No.2","starting_page":"146","ending_page":"152","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11246/gakukansetsu1989.17.146"],"issn":["0915-3004"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:170, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/15472659","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249870","label":"url"}],"paper_title":{"en":"Self-reported remission, difficulty, and satisfaction with nonsurgical therapy used to treat anterior disc displacement without reduction.","ja":"Self-reported remission, difficulty, and satisfaction with nonsurgical therapy used to treat anterior disc displacement without reduction."},"authors":{"en":[{"name":"Minakuchi H"},{"name":"Kuboki T"},{"name":"Maekawa K"},{"name":"Matsuka Yoshizo"},{"name":"Yatani H"}],"ja":[{"name":"Minakuchi H"},{"name":"Kuboki T"},{"name":"Maekawa K"},{"name":"松香 芳三"},{"name":"Yatani H"}]},"description":{"en":"These data suggest that palliative care would be more appropriate as the initial therapy to treat painful anterior disc displacement without reduction.","ja":"These data suggest that palliative care would be more appropriate as the initial therapy to treat painful anterior disc displacement without reduction."},"publication_date":"2004-10","publication_name":{"en":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics","ja":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics"},"volume":"Vol.98","number":"No.4","starting_page":"435","ending_page":"440","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.tripleo.2003.11.013"],"issn":["1079-2104"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:171, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10012837830/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282679398109184/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250028","label":"url"}],"paper_title":{"en":"Clinical and MRI characteristics of patients unresponsive to conservative treatment for TMJ anterior disc displacement without reduction","ja":"保存療法が有効ではなかった非復位性顎関節円板前方転位症例の臨床所見ならびにMRI所見の検討"},"authors":{"en":[{"name":"岩瀬 博建"},{"name":"佐々木 忠昭"},{"name":"麻野 和宏"},{"name":"Matsuka Yoshizo"},{"name":"マイトリラタナクル サムサック"},{"name":"今井 裕"}],"ja":[{"name":"岩瀬 博建"},{"name":"佐々木 忠昭"},{"name":"麻野 和宏"},{"name":"松香 芳三"},{"name":"マイトリラタナクル サムサック"},{"name":"今井 裕"}]},"publication_date":"2004-04-20","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.16","number":"No.1","starting_page":"13","ending_page":"18","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.11246/gakukansetsu1989.16.13"],"issn":["0915-3004"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:172, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10012436547/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001205194897408/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=251612","label":"url"}],"paper_title":{"en":"Gender differences in neuroselective current perception thresholds of the trigeminal and median nerves","ja":"Gender differences in neuroselective current perception thresholds of the trigeminal and median nerves"},"authors":{"en":[{"name":"Nakazawa Y"},{"name":"Yatani Hirofumi"},{"name":"Minakuchi Hajime"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"Nakazawa Y"},{"name":"Yatani Hirofumi"},{"name":"Minakuchi Hajime"},{"name":"松香 芳三"}]},"description":{"en":"Purpose : The goal of this study was to ascertain gender differences in sensory thresholds by measuring current perception threshold (CPT) values of the trigeminal and median nerves in healthy individuals.Materials and Methods : CPT values were measured using a Neurometer® (Neurotoron, Baltimore, MD, USA) when electrical stimulation of 2, 000, 250, or 5 Hz was applied to the left preauricular (trigeminal nerve) and thenar eminence (median nerve) regions in 20 healthy volunteers (10 males and 10 females with a mean age of 24.4 years). The day-to-day reliability of CPT was first verified in the trigeminal region by a test-retest method using an interclass correlation coefficient (ICC). The CPT values were then measured and statistically analyzed to evaluate whether the values were influenced by the electrical stimulation frequency and gender difference.Results : Irrespective of the stimulation frequency, the ICC values were high (2, 000 Hz : 0.62, 250 Hz : 0.80, 5 Hz : 0.86), showing the high day-to-day reliability of CPT. The electrical frequency of the stimulation significantly influenced the CPT (ANOVA : p<0.0001) ; the mean CPT value during 2, 000 Hz stimulation was significantly higher than the value during 250 and 5 Hz stimulation (Bonferroni test : p<0.001). For median nerve stimulation, the mean CPT was lower for women than for men, but no significant gender difference was identified (ANOVA : p=0.11). Conversely, gender exerted significant effects on CPTs (ANOVA : p=0.02) for trigeminal nerve simulation. As to stimulation frequency, the mean CPT following 2, 000 Hz stimulation of the trigeminal nerve was significantly lower for women than for men (Bonferroni test : p<0.001).Conclusion : The results suggest that healthy women are more sensitive to tactile or pressure sensations compared to healthy men, and that the effects of gender differences on the sensory threshold can be ignored with pain-related nerve fibers such as Aδ and C fibers.","ja":"Purpose : The goal of this study was to ascertain gender differences in sensory thresholds by measuring current perception threshold (CPT) values of the trigeminal and median nerves in healthy individuals.Materials and Methods : CPT values were measured using a Neurometer® (Neurotoron, Baltimore, MD, USA) when electrical stimulation of 2, 000, 250, or 5 Hz was applied to the left preauricular (trigeminal nerve) and thenar eminence (median nerve) regions in 20 healthy volunteers (10 males and 10 females with a mean age of 24.4 years). The day-to-day reliability of CPT was first verified in the trigeminal region by a test-retest method using an interclass correlation coefficient (ICC). The CPT values were then measured and statistically analyzed to evaluate whether the values were influenced by the electrical stimulation frequency and gender difference.Results : Irrespective of the stimulation frequency, the ICC values were high (2, 000 Hz : 0.62, 250 Hz : 0.80, 5 Hz : 0.86), showing the high day-to-day reliability of CPT. The electrical frequency of the stimulation significantly influenced the CPT (ANOVA : p<0.0001) ; the mean CPT value during 2, 000 Hz stimulation was significantly higher than the value during 250 and 5 Hz stimulation (Bonferroni test : p<0.001). For median nerve stimulation, the mean CPT was lower for women than for men, but no significant gender difference was identified (ANOVA : p=0.11). Conversely, gender exerted significant effects on CPTs (ANOVA : p=0.02) for trigeminal nerve simulation. As to stimulation frequency, the mean CPT following 2, 000 Hz stimulation of the trigeminal nerve was significantly lower for women than for men (Bonferroni test : p<0.001).Conclusion : The results suggest that healthy women are more sensitive to tactile or pressure sensations compared to healthy men, and that the effects of gender differences on the sensory threshold can be ignored with pain-related nerve fibers such as Aδ and C fibers."},"publication_date":"2003-10-01","publication_name":{"en":"Prosthodontic Research & Practice","ja":"Prosthodontic Research & Practice"},"volume":"Vol.2","number":"No.1","starting_page":"72","ending_page":"75","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2186/prp.2.72"],"issn":["1347-7021"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:173, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/13679399","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249871","label":"url"}],"paper_title":{"en":"Hyperosmolar solutions selectively block action potentials in rat myelinated sensory fibers: implications for diabetic neuropathy.","ja":"Hyperosmolar solutions selectively block action potentials in rat myelinated sensory fibers: implications for diabetic neuropathy."},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Spigelman Igor"}],"ja":[{"name":"松香 芳三"},{"name":"Spigelman Igor"}]},"description":{"en":"Diabetic neuropathy is a common complication of diabetes mellitus patients. It is a wide range of abnormalities affecting proximal and distal peripheral sensory and motor nerves. Although plasma hyperosmolality is a common finding in diabetes mellitus, the effects of hyperosmolality on conduction of various sensory signal components have not been addressed in detail. Here we show that in rat dorsal root ganglion (DRG) preparations from normal rats, hyperosmolar solutions (360 mmol/kg, containing increased glucose, sucrose, NaCl, or mannitol) produce a selective block of signal propagation in myelinated sensory A-fibers. In compound action potential (CAP) recordings with suction electrodes, peak A-fiber CAP amplitude was selectively decreased (20%), while the C-fiber peak remained intact or was slightly increased. Hyperosmolar solutions had smaller effects on conduction velocity (CV) of both A- and C-fibers (approximately 5% decrease). Hyperosmolality-induced CAP changes could not be observed during recordings from isolated spinal nerves but were evident during recordings from desheathed spinal nerves. In intracellular recordings, hyperosmolar solutions produced a block of spinal nerve-evoked action potential invasion into the somata of some A-fiber neurons. Removal of extracellular calcium completely prevented the hyperosmolality-induced CAP decreases. Based on these data, we propose that the decreased CAP amplitudes recorded in human patients and in animal models of diabetes are in part due to the effects of hyperosmolality and would depend on the extracellular osmolality at the time of sensory testing. We also hypothesize that hyperosmolality may contribute to both the sensory abnormalities (paresthesias) and the chronic pain symptoms of diabetic neuropathy.","ja":"Diabetic neuropathy is a common complication of diabetes mellitus patients. It is a wide range of abnormalities affecting proximal and distal peripheral sensory and motor nerves. Although plasma hyperosmolality is a common finding in diabetes mellitus, the effects of hyperosmolality on conduction of various sensory signal components have not been addressed in detail. Here we show that in rat dorsal root ganglion (DRG) preparations from normal rats, hyperosmolar solutions (360 mmol/kg, containing increased glucose, sucrose, NaCl, or mannitol) produce a selective block of signal propagation in myelinated sensory A-fibers. In compound action potential (CAP) recordings with suction electrodes, peak A-fiber CAP amplitude was selectively decreased (20%), while the C-fiber peak remained intact or was slightly increased. Hyperosmolar solutions had smaller effects on conduction velocity (CV) of both A- and C-fibers (approximately 5% decrease). Hyperosmolality-induced CAP changes could not be observed during recordings from isolated spinal nerves but were evident during recordings from desheathed spinal nerves. In intracellular recordings, hyperosmolar solutions produced a block of spinal nerve-evoked action potential invasion into the somata of some A-fiber neurons. Removal of extracellular calcium completely prevented the hyperosmolality-induced CAP decreases. Based on these data, we propose that the decreased CAP amplitudes recorded in human patients and in animal models of diabetes are in part due to the effects of hyperosmolality and would depend on the extracellular osmolality at the time of sensory testing. We also hypothesize that hyperosmolality may contribute to both the sensory abnormalities (paresthesias) and the chronic pain symptoms of diabetic neuropathy."},"publication_date":"2003-09-17","publication_name":{"en":"Journal of Neurophysiology","ja":"Journal of Neurophysiology"},"volume":"Vol.91","number":"No.1","starting_page":"48","ending_page":"56","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1152/jn.00689.2003"],"issn":["0022-3077"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:174, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12699788","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249872","label":"url"}],"paper_title":{"en":"Relationship between capsaicin-evoked substance P release and neurokinin 1 receptor internalization in the rat spinal cord.","ja":"Relationship between capsaicin-evoked substance P release and neurokinin 1 receptor internalization in the rat spinal cord."},"authors":{"en":[{"name":"Marvizón J C G"},{"name":"Wang X"},{"name":"Matsuka Yoshizo"},{"name":"Neubert J K"},{"name":"Spigelman I"}],"ja":[{"name":"Marvizón J C G"},{"name":"Wang X"},{"name":"松香 芳三"},{"name":"Neubert J K"},{"name":"Spigelman I"}]},"description":{"en":"The relationship between substance P release and the activation of its receptor in the spinal cord remains unclear. Substance P release is usually measured by radioimmunoassay, whereas the internalization of the neurokinin 1 (NK1) receptor has been used to assess its activation by noxious stimuli. Our objective was to compare substance P release and NK1 receptor internalization produced by capsaicin in rat spinal cord slices. Superfusion of the slices with capsaicin for 3 min produced a gradual increase in substance P release that peaked 3-7 min afterward, and then decreased to baseline levels. The concentration-response curve for capsaicin was biphasic, with concentrations above 10 microM producing significantly less release. The effective concentration for 50% of response (EC(50)) for capsaicin, calculated from its stimulatory phase, was 2.3 microM. However, the potency of capsaicin to elicit NK1 receptor internalization in the same slices was one order of magnitude higher (EC(50)=0.37 microM) in lamina I, probably because NK1 receptors become saturated at relatively low concentrations of substance P. The potency of capsaicin to produce internalization was progressively lower in lamina III (EC(50)=1.9 microM) and lamina IV (EC(50)=14.5 microM), suggesting that neurokinins released in laminae I-II become diluted as they diffuse to the inner dorsal horn. To study the correlation between these two measures, we plotted substance P release against NK1 receptor internalization and fitted a saturation binding function to the points. The correlation was good for laminae I (R(2)=0.82) and III (R(2)=0.78), but it was poor (R(2)=0.35) for lamina IV because NK1 receptor internalization kept on increasing at high concentrations of capsaicin, whereas substance P release decreased. In conclusion, amounts of substance P able to activate NK1 receptors may fall under the threshold of detection of radioimmunoassay. Conversely, radioimmunoassay often detects levels of substance P release well over those required to saturate NK1 receptors in the superficial dorsal horn, but that may be able to activate these receptors in nearby regions of the spinal cord.","ja":"The relationship between substance P release and the activation of its receptor in the spinal cord remains unclear. Substance P release is usually measured by radioimmunoassay, whereas the internalization of the neurokinin 1 (NK1) receptor has been used to assess its activation by noxious stimuli. Our objective was to compare substance P release and NK1 receptor internalization produced by capsaicin in rat spinal cord slices. Superfusion of the slices with capsaicin for 3 min produced a gradual increase in substance P release that peaked 3-7 min afterward, and then decreased to baseline levels. The concentration-response curve for capsaicin was biphasic, with concentrations above 10 microM producing significantly less release. The effective concentration for 50% of response (EC(50)) for capsaicin, calculated from its stimulatory phase, was 2.3 microM. However, the potency of capsaicin to elicit NK1 receptor internalization in the same slices was one order of magnitude higher (EC(50)=0.37 microM) in lamina I, probably because NK1 receptors become saturated at relatively low concentrations of substance P. The potency of capsaicin to produce internalization was progressively lower in lamina III (EC(50)=1.9 microM) and lamina IV (EC(50)=14.5 microM), suggesting that neurokinins released in laminae I-II become diluted as they diffuse to the inner dorsal horn. To study the correlation between these two measures, we plotted substance P release against NK1 receptor internalization and fitted a saturation binding function to the points. The correlation was good for laminae I (R(2)=0.82) and III (R(2)=0.78), but it was poor (R(2)=0.35) for lamina IV because NK1 receptor internalization kept on increasing at high concentrations of capsaicin, whereas substance P release decreased. In conclusion, amounts of substance P able to activate NK1 receptors may fall under the threshold of detection of radioimmunoassay. Conversely, radioimmunoassay often detects levels of substance P release well over those required to saturate NK1 receptors in the superficial dorsal horn, but that may be able to activate these receptors in nearby regions of the spinal cord."},"publication_date":"2003","publication_name":{"en":"Neuroscience","ja":"Neuroscience"},"volume":"Vol.118","number":"No.2","starting_page":"535","ending_page":"545","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0306-4522(02)00977-6"],"issn":["0306-4522"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:175, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12431709","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249874","label":"url"}],"paper_title":{"en":"Microdialysis in trigeminal ganglia.","ja":"Microdialysis in trigeminal ganglia."},"authors":{"en":[{"name":"Neubert John K"},{"name":"Matsuka Yoshizo"},{"name":"Maidment Nigel T"},{"name":"Spigelman Igor"}],"ja":[{"name":"Neubert John K"},{"name":"松香 芳三"},{"name":"Maidment Nigel T"},{"name":"Spigelman Igor"}]},"description":{"en":"Recent evidence demonstrates that neurons in sensory ganglia contribute to sensory signaling in both physiological and pathological states. In vivo sampling from this site may provide important insights into which substances mediate or modulate sensory transmission. To address this possibility, we have applied the microdialysis technique to the guinea pig trigeminal ganglia (TG). The large size and easy access of the TG in the guinea pig make it an ideal sampling site, while the somatotopic organization allows for specific regions of innervation to be studied at the ganglionic level. This report describes the use of microdialysis probes within the TG and use recovery and analysis of substance P (SP) and adenosine triphosphate (ATP) as case in points. Various physiological and pharmacological manipulations can be made, for example release of peptides from ganglionic neurons can be monitored in the presence or absence of inflammation in the orofacial region. Microdialysis performed in the TG thus provides a valuable site for recovery and measurement of a variety of extracellular substances that may be integral in the processing of trigeminal sensory information.","ja":"Recent evidence demonstrates that neurons in sensory ganglia contribute to sensory signaling in both physiological and pathological states. In vivo sampling from this site may provide important insights into which substances mediate or modulate sensory transmission. To address this possibility, we have applied the microdialysis technique to the guinea pig trigeminal ganglia (TG). The large size and easy access of the TG in the guinea pig make it an ideal sampling site, while the somatotopic organization allows for specific regions of innervation to be studied at the ganglionic level. This report describes the use of microdialysis probes within the TG and use recovery and analysis of substance P (SP) and adenosine triphosphate (ATP) as case in points. Various physiological and pharmacological manipulations can be made, for example release of peptides from ganglionic neurons can be monitored in the presence or absence of inflammation in the orofacial region. Microdialysis performed in the TG thus provides a valuable site for recovery and measurement of a variety of extracellular substances that may be integral in the processing of trigeminal sensory information."},"publication_date":"2002-10","publication_name":{"en":"Brain Research. Brain Research Protocols","ja":"Brain Research. Brain Research Protocols"},"volume":"Vol.10","number":"No.2","starting_page":"102","ending_page":"108","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S1385-299X(02)00188-5"],"issn":["1385-299X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:176, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12153450","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249875","label":"url"}],"paper_title":{"en":"Pressure-pain threshold determination in the oral mucosa: validity and reliability.","ja":"Pressure-pain threshold determination in the oral mucosa: validity and reliability."},"authors":{"en":[{"name":"Ogimoto T"},{"name":"Ogawa T"},{"name":"Sumiyoshi K"},{"name":"Matsuka Yoshizo"},{"name":"Koyano K"}],"ja":[{"name":"Ogimoto T"},{"name":"Ogawa T"},{"name":"Sumiyoshi K"},{"name":"松香 芳三"},{"name":"Koyano K"}]},"description":{"en":"Fundamental knowledge of pain in the oral mucosa is lacking. We determined the validity and reliability of the pressure-pain threshold (PPT) measurement in the oral mucosa using a newly developed hand-held pressure algometer. Ten dentulous subjects were recruited, and the PPT was measured at the bilateral buccal (on the attached gingiva apical to the midline of the upper first premolars, 3 mm from the mucogingival junction) and the palatal sites (mid-point between the bilateral upper first molars). The PPT linearly increased with an increase in load-rate (P < 0.0001). The PPT yielded a high intra-individual stability both for the same-day consecutive trials and weekly sessions. The palatal site revealed a 4- to 4.65-fold greater PPT than the buccal sites (Bonferroni, P < 0.0001), whereas no difference was found between the bilateral buccal sites (P=0.663). Despite a great interindividual variation in the PPT, significant intra-individual correlations were found among the measurement sites. This suggested differences in individual sensitivity to pain in the oral mucosa, which may determine overall pain sensation specific to an individual. A pressure algometer described herein reliably assessed the PPT in the oral mucosa and sensitively discriminated PPT differences at different sites and at different load-rates, suggesting the reliability and validity of PPT measurements in the oral mucosa for clinical and research investigations.","ja":"Fundamental knowledge of pain in the oral mucosa is lacking. We determined the validity and reliability of the pressure-pain threshold (PPT) measurement in the oral mucosa using a newly developed hand-held pressure algometer. Ten dentulous subjects were recruited, and the PPT was measured at the bilateral buccal (on the attached gingiva apical to the midline of the upper first premolars, 3 mm from the mucogingival junction) and the palatal sites (mid-point between the bilateral upper first molars). The PPT linearly increased with an increase in load-rate (P < 0.0001). The PPT yielded a high intra-individual stability both for the same-day consecutive trials and weekly sessions. The palatal site revealed a 4- to 4.65-fold greater PPT than the buccal sites (Bonferroni, P < 0.0001), whereas no difference was found between the bilateral buccal sites (P=0.663). Despite a great interindividual variation in the PPT, significant intra-individual correlations were found among the measurement sites. This suggested differences in individual sensitivity to pain in the oral mucosa, which may determine overall pain sensation specific to an individual. A pressure algometer described herein reliably assessed the PPT in the oral mucosa and sensitively discriminated PPT differences at different sites and at different load-rates, suggesting the reliability and validity of PPT measurements in the oral mucosa for clinical and research investigations."},"publication_date":"2002-07","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.29","number":"No.7","starting_page":"620","ending_page":"626","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1046/j.1365-2842.2002.00874.x"],"issn":["0305-182X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:177, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11595216","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0035850896&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249876","label":"url"}],"paper_title":{"en":"Concurrent release of ATP and substance P within guinea pig trigeminal ganglia in vivo.","ja":"Concurrent release of ATP and substance P within guinea pig trigeminal ganglia in vivo."},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Neubert J K"},{"name":"Maidment N T"},{"name":"Spigelman I"}],"ja":[{"name":"松香 芳三"},{"name":"Neubert J K"},{"name":"Maidment N T"},{"name":"Spigelman I"}]},"description":{"en":"Neurons within sensory ganglia have been proposed to communicate via non-synaptic release of a diffusible chemical messenger, but the identity of the chemical mediator(s) remains unknown [J. Neurosci. 16 (1996) 4733-4741]. The present study addressed the possibility of co-released ATP and substance P (SP) within sensory ganglia to further advance the hypothesis of non-synaptic communication between sensory neurons. Microdialysis probes inserted into trigeminal ganglia (TRGs) of anesthetized guinea pigs were perfused with artificial cerebrospinal fluid and the collected perfusate analyzed for ATP and SP content using the firefly luciferin-luciferase (L/L) assay and radioimmunoassay, respectively. Significant reversible increases in ATP and SP levels were observed after infusion of 100 mM KCl or 1 mM capsaicin. Ca(2+)-free ACSF produced an eightfold increase in ATP levels, interpreted as a decrease in activity of Ca(2+)-dependent ecto-nucleotidases that degrade ATP. In contrast, KCl-induced release of ATP in the presence of normal Ca(2+) was blocked by Cd(2+), a voltage-gated Ca(2+) channel blocker, illustrating Ca(2+)-dependence of evoked ATP release. Since ganglionic release of ATP could arise from several neuronal and non-neuronal sources we directly tested acutely dissociated TRG neuron somata for ATP release. Neuron-enriched dissociated TRG cells were plated onto glass tubes and tested for ATP release using the L/L assay. Robust ATP release was evoked with 5 microM capsaicin. These data suggest that ATP is released concurrently with SP from the somata of neurons within sensory ganglia.","ja":"Neurons within sensory ganglia have been proposed to communicate via non-synaptic release of a diffusible chemical messenger, but the identity of the chemical mediator(s) remains unknown [J. Neurosci. 16 (1996) 4733-4741]. The present study addressed the possibility of co-released ATP and substance P (SP) within sensory ganglia to further advance the hypothesis of non-synaptic communication between sensory neurons. Microdialysis probes inserted into trigeminal ganglia (TRGs) of anesthetized guinea pigs were perfused with artificial cerebrospinal fluid and the collected perfusate analyzed for ATP and SP content using the firefly luciferin-luciferase (L/L) assay and radioimmunoassay, respectively. Significant reversible increases in ATP and SP levels were observed after infusion of 100 mM KCl or 1 mM capsaicin. Ca(2+)-free ACSF produced an eightfold increase in ATP levels, interpreted as a decrease in activity of Ca(2+)-dependent ecto-nucleotidases that degrade ATP. In contrast, KCl-induced release of ATP in the presence of normal Ca(2+) was blocked by Cd(2+), a voltage-gated Ca(2+) channel blocker, illustrating Ca(2+)-dependence of evoked ATP release. Since ganglionic release of ATP could arise from several neuronal and non-neuronal sources we directly tested acutely dissociated TRG neuron somata for ATP release. Neuron-enriched dissociated TRG cells were plated onto glass tubes and tested for ATP release using the L/L assay. Robust ATP release was evoked with 5 microM capsaicin. These data suggest that ATP is released concurrently with SP from the somata of neurons within sensory ganglia."},"publication_date":"2001-10-12","publication_name":{"en":"Brain Research","ja":"Brain Research"},"volume":"Vol.915","number":"No.2","starting_page":"248","ending_page":"255","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0006-8993(01)02888-8"],"issn":["0006-8993"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:178, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11379897","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249877","label":"url"}],"paper_title":{"en":"Randomized controlled evaluation of non-surgical treatments for temporomandibular joint anterior disk displacement without reduction.","ja":"Randomized controlled evaluation of non-surgical treatments for temporomandibular joint anterior disk displacement without reduction."},"authors":{"en":[{"name":"Minakuchi H"},{"name":"Kuboki T"},{"name":"Matsuka Yoshizo"},{"name":"Maekawa K"},{"name":"Yatani H"},{"name":"Yamashita A"}],"ja":[{"name":"Minakuchi H"},{"name":"Kuboki T"},{"name":"松香 芳三"},{"name":"Maekawa K"},{"name":"Yatani H"},{"name":"Yamashita A"}]},"description":{"en":"The common methods for treating anterior disk displacement without reduction (ADDwor) are not based on randomized controlled clinical trials. Our study evaluated non-surgical treatments in 69 MRI-confirmed ADDwor subjects (m/f = 6/63). Subjects were randomly assigned to a control group and one of two treatment groups. Outcomes included maximum mouth opening, visual analogue scale of pain, and daily activity limitation. Calibrated examiners collected data at the initial interview and at 0, 2, 4, and 8 weeks of treatment. At the eight-week point, within-group improvements were present for all variables, for all groups. Between-group differences were not highly evident, with only mean daily activity limitation for the self-care/NSAID group being significantly lower than that of the occlusal appliance/jaw mobilization + self-care/NSAID group at the two- and four-week time-points. These results suggest that ADDwor subjects will improve with only minimal treatment intervention, and no significant difference was evident for the treatments tested and the control condition.","ja":"The common methods for treating anterior disk displacement without reduction (ADDwor) are not based on randomized controlled clinical trials. Our study evaluated non-surgical treatments in 69 MRI-confirmed ADDwor subjects (m/f = 6/63). Subjects were randomly assigned to a control group and one of two treatment groups. Outcomes included maximum mouth opening, visual analogue scale of pain, and daily activity limitation. Calibrated examiners collected data at the initial interview and at 0, 2, 4, and 8 weeks of treatment. At the eight-week point, within-group improvements were present for all variables, for all groups. Between-group differences were not highly evident, with only mean daily activity limitation for the self-care/NSAID group being significantly lower than that of the occlusal appliance/jaw mobilization + self-care/NSAID group at the two- and four-week time-points. These results suggest that ADDwor subjects will improve with only minimal treatment intervention, and no significant difference was evident for the treatments tested and the control condition."},"publication_date":"2001-03","publication_name":{"en":"Journal of Dental Research","ja":"Journal of Dental Research"},"volume":"Vol.80","number":"No.3","starting_page":"924","ending_page":"928","languages":["eng"],"referee":true,"identifiers":{"issn":["0022-0345"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:179, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797138"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250029","label":"url"}],"paper_title":{"en":"一般歯科医院の受診患者における顎関節症の症状と徴候の変動","ja":"一般歯科医院の受診患者における顎関節症の症状と徴候の変動"},"authors":{"en":[{"name":"西村 真紀"},{"name":"景山 正登"},{"name":"Matsuka Yoshizo"},{"name":"畑中 乾志"},{"name":"吉田 栄介"},{"name":"水口 一"},{"name":"窪木 拓男"},{"name":"矢谷 博文"}],"ja":[{"name":"西村 真紀"},{"name":"景山 正登"},{"name":"松香 芳三"},{"name":"畑中 乾志"},{"name":"吉田 栄介"},{"name":"水口 一"},{"name":"窪木 拓男"},{"name":"矢谷 博文"}]},"publication_date":"2001","publication_name":{"en":"The Journal of the Japan Association of Cranio-Mandibular Orthopedics","ja":"日本顎頭蓋機能学会誌"},"volume":"Vol.14","number":"No.1","starting_page":"23","ending_page":"31","languages":["jpn"],"referee":true,"identifiers":{"issn":["1340-8852"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:180, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11251780","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249985","label":"url"}],"paper_title":{"en":"Rehabilitation of biting abilities in patients with different types of dental prostheses.","ja":"Rehabilitation of biting abilities in patients with different types of dental prostheses."},"authors":{"en":[{"name":"Miyaura K"},{"name":"Morita M"},{"name":"Matsuka Yoshizo"},{"name":"Yamashita A"},{"name":"Watanabe T"}],"ja":[{"name":"Miyaura K"},{"name":"Morita M"},{"name":"松香 芳三"},{"name":"Yamashita A"},{"name":"Watanabe T"}]},"description":{"en":"This study investigated the masticatory rehabilitation of subjects wearing different types of prostheses. Biting abilities per person (biting force, biting pressure and occlusal contact area) were assessed with a pressure detecting sheet (Prescale(R)). Five hundred and ninety volunteers were divided into four groups according to the type of posterior dentition: complete denture, removable partial denture, fixed partial denture, and full natural dentition groups. The biting forces of the fixed partial, removable partial and complete denture wearers were 80, 35 and 11% respectively, when expressed as a percentage of the subjects with a natural dentition. The complete denture wearers showed the highest biting pressure among the four groups, followed by the removable partial denture wearers. In a clinical intra-individual study, the biting abilities of 85 subjects, without (before insertion of) and with (after insertion of) renewed prostheses, were compared. No significant differences were found between biting before and immediately after insertion of the prostheses. However, the biting force and occlusal contact area increased 2 months after insertion of the prostheses. This study confirmed past clinical studies indicating an impaired masticatory function of denture wearers. The functional adaptation to new prostheses had improved at evaluation 2 months after insertion.","ja":"This study investigated the masticatory rehabilitation of subjects wearing different types of prostheses. Biting abilities per person (biting force, biting pressure and occlusal contact area) were assessed with a pressure detecting sheet (Prescale(R)). Five hundred and ninety volunteers were divided into four groups according to the type of posterior dentition: complete denture, removable partial denture, fixed partial denture, and full natural dentition groups. The biting forces of the fixed partial, removable partial and complete denture wearers were 80, 35 and 11% respectively, when expressed as a percentage of the subjects with a natural dentition. The complete denture wearers showed the highest biting pressure among the four groups, followed by the removable partial denture wearers. In a clinical intra-individual study, the biting abilities of 85 subjects, without (before insertion of) and with (after insertion of) renewed prostheses, were compared. No significant differences were found between biting before and immediately after insertion of the prostheses. However, the biting force and occlusal contact area increased 2 months after insertion of the prostheses. This study confirmed past clinical studies indicating an impaired masticatory function of denture wearers. The functional adaptation to new prostheses had improved at evaluation 2 months after insertion."},"publication_date":"2000-12","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.27","number":"No.12","starting_page":"1073","ending_page":"1076","languages":["eng"],"referee":true,"identifiers":{"issn":["0305-182X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:181, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10899285","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0034698238&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249988","label":"url"}],"paper_title":{"en":"Inflammation-induced changes in primary afferent-evoked release of substance P within trigeminal ganglia in vivo.","ja":"Inflammation-induced changes in primary afferent-evoked release of substance P within trigeminal ganglia in vivo."},"authors":{"en":[{"name":"Neubert J K"},{"name":"Maidment N T"},{"name":"Matsuka Yoshizo"},{"name":"Adelson D W"},{"name":"Kruger L"},{"name":"Spigelman I"}],"ja":[{"name":"Neubert J K"},{"name":"Maidment N T"},{"name":"松香 芳三"},{"name":"Adelson D W"},{"name":"Kruger L"},{"name":"Spigelman I"}]},"description":{"en":"Substance P (SP) is synthesized in a subset of nociceptive sensory neurons and is released from their peripheral and central terminals. Here we demonstrate with the use of in vivo microdialysis and radioimmunoassay techniques that SP is also released within trigeminal ganglia following intraganglionic application of KCl, veratridine or capsaicin, and after electrical stimulation of peripheral afferent fibers. Both the basal and KCl-evoked release of SP are shown to be dependent on extracellular calcium. Using the turpentine-induced model of unilateral orofacial inflammation we also show that both the basal and KCl-evoked release of SP within trigeminal ganglia are greatly increased on the inflamed side 48 h after induction of inflammation. Coupled with previous demonstrations of excitatory effects of SP on sensory neurons, these results suggest that SP fulfils the role of a non-synaptically released diffusible chemical messenger that may modulate the somatic excitability of neurons within sensory ganglia in inflammatory pain states.","ja":"Substance P (SP) is synthesized in a subset of nociceptive sensory neurons and is released from their peripheral and central terminals. Here we demonstrate with the use of in vivo microdialysis and radioimmunoassay techniques that SP is also released within trigeminal ganglia following intraganglionic application of KCl, veratridine or capsaicin, and after electrical stimulation of peripheral afferent fibers. Both the basal and KCl-evoked release of SP are shown to be dependent on extracellular calcium. Using the turpentine-induced model of unilateral orofacial inflammation we also show that both the basal and KCl-evoked release of SP within trigeminal ganglia are greatly increased on the inflamed side 48 h after induction of inflammation. Coupled with previous demonstrations of excitatory effects of SP on sensory neurons, these results suggest that SP fulfils the role of a non-synaptically released diffusible chemical messenger that may modulate the somatic excitability of neurons within sensory ganglia in inflammatory pain states."},"publication_date":"2000-07-21","publication_name":{"en":"Brain Research","ja":"Brain Research"},"volume":"Vol.871","number":"No.2","starting_page":"181","ending_page":"191","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0006-8993(00)02440-9"],"issn":["0006-8993"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:182, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11203749","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249987","label":"url"}],"paper_title":{"en":"Trigeminal neuralgia due to an acoustic neuroma in the cerebellopontine angle.","ja":"Trigeminal neuralgia due to an acoustic neuroma in the cerebellopontine angle."},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Fort E T"},{"name":"Merrill R L"}],"ja":[{"name":"松香 芳三"},{"name":"Fort E T"},{"name":"Merrill R L"}]},"description":{"en":"This case report first reviews the intracranial tumors associated with symptoms of trigeminal neuralgia (TN). Among patients with TN-like symptoms, 6 to 16% are variously reported to have intracranial tumors. The most common cerebellopontine angle (CPA) tumor to cause TN-like symptoms is a benign tumor called an acoustic neuroma. The reported clinical symptoms of the acoustic neuroma are hearing deficits (60 to 97%), tinnitus (50 to 66%), vestibular disturbances (46 to 59%), numbness or tingling in the face (33%), headache (19 to 29%), dizziness (23%), facial paresis (17%), and trigeminal nerve disturbances (hypesthesia, paresthesia, and neuralgia) (12 to 45%). Magnetic resonance imaging with gadolinium enhancement or computed tomography with contrast media are each reported to have excellent abilities to detect intracranial tumors (92 to 93%). This article then reports a rare case of a young female patient who was mistakenly diagnosed and treated for a temporomandibular disorder but was subsequently found to have an acoustic neuroma located in the CPA.","ja":"This case report first reviews the intracranial tumors associated with symptoms of trigeminal neuralgia (TN). Among patients with TN-like symptoms, 6 to 16% are variously reported to have intracranial tumors. The most common cerebellopontine angle (CPA) tumor to cause TN-like symptoms is a benign tumor called an acoustic neuroma. The reported clinical symptoms of the acoustic neuroma are hearing deficits (60 to 97%), tinnitus (50 to 66%), vestibular disturbances (46 to 59%), numbness or tingling in the face (33%), headache (19 to 29%), dizziness (23%), facial paresis (17%), and trigeminal nerve disturbances (hypesthesia, paresthesia, and neuralgia) (12 to 45%). Magnetic resonance imaging with gadolinium enhancement or computed tomography with contrast media are each reported to have excellent abilities to detect intracranial tumors (92 to 93%). This article then reports a rare case of a young female patient who was mistakenly diagnosed and treated for a temporomandibular disorder but was subsequently found to have an acoustic neuroma located in the CPA."},"publication_date":"2000","publication_name":{"en":"Journal of Orofacial Pain","ja":"Journal of Orofacial Pain"},"volume":"Vol.14","number":"No.2","starting_page":"147","ending_page":"151","languages":["eng"],"referee":true,"identifiers":{"issn":["1064-6655"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:183, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11203757","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249986","label":"url"}],"paper_title":{"en":"Four-year longitudinal course of TMD symptoms in an adult population and the estimation of risk factors in relation to symptoms.","ja":"Four-year longitudinal course of TMD symptoms in an adult population and the estimation of risk factors in relation to symptoms."},"authors":{"en":[{"name":"Kamisaka M"},{"name":"Yatani H"},{"name":"Kuboki T"},{"name":"Matsuka Yoshizo"},{"name":"Minakuchi H"}],"ja":[{"name":"Kamisaka M"},{"name":"Yatani H"},{"name":"Kuboki T"},{"name":"松香 芳三"},{"name":"Minakuchi H"}]},"description":{"en":"The possible etiologic significance of these factors in TMD should be validated by future research.","ja":"The possible etiologic significance of these factors in TMD should be validated by future research."},"publication_date":"2000","publication_name":{"en":"Journal of Orofacial Pain","ja":"Journal of Orofacial Pain"},"volume":"Vol.14","number":"No.3","starting_page":"224","ending_page":"232","languages":["eng"],"referee":true,"identifiers":{"issn":["1064-6655"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:184, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10194731","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0033093946&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249989","label":"url"}],"paper_title":{"en":"Comparison of biting forces in different age and sex groups: a study of biting efficiency with mobile and non-mobile teeth.","ja":"Comparison of biting forces in different age and sex groups: a study of biting efficiency with mobile and non-mobile teeth."},"authors":{"en":[{"name":"Miyaura K"},{"name":"Matsuka Yoshizo"},{"name":"Morita M"},{"name":"Yamashita A"},{"name":"Watanabe T"}],"ja":[{"name":"Miyaura K"},{"name":"松香 芳三"},{"name":"Morita M"},{"name":"Yamashita A"},{"name":"Watanabe T"}]},"description":{"en":"This study aimed (1) to investigate the influences of sex, age and number of teeth on biting ability through a descriptive survey, and (2) to compare the biting ability between the subjects with and without mobile teeth in a case-control study. A total of 687 subjects cooperated in the descriptive survey. Each subject bit on a pressure detecting sheet with their maximum biting force. Three indices of biting ability: biting pressure (MPa), biting force (N) and occlusal contact area (mm2) were calculated from the impressed marks on the sheet using a high vision video processor system. These indices were correlated well with the number of teeth according to the multiple regression analysis. In the case-control study, matching procedures with sex, age and number of teeth were performed between the subjects with and without mobile teeth. No differences in the three indices were observed between the two well-balanced groups. The results showed that the number of teeth is most important to maintain biting ability, and that the presence of mobile teeth does not always reduce biting ability.","ja":"This study aimed (1) to investigate the influences of sex, age and number of teeth on biting ability through a descriptive survey, and (2) to compare the biting ability between the subjects with and without mobile teeth in a case-control study. A total of 687 subjects cooperated in the descriptive survey. Each subject bit on a pressure detecting sheet with their maximum biting force. Three indices of biting ability: biting pressure (MPa), biting force (N) and occlusal contact area (mm2) were calculated from the impressed marks on the sheet using a high vision video processor system. These indices were correlated well with the number of teeth according to the multiple regression analysis. In the case-control study, matching procedures with sex, age and number of teeth were performed between the subjects with and without mobile teeth. No differences in the three indices were observed between the two well-balanced groups. The results showed that the number of teeth is most important to maintain biting ability, and that the presence of mobile teeth does not always reduce biting ability."},"publication_date":"1999-03","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.26","number":"No.3","starting_page":"223","ending_page":"227","languages":["eng"],"referee":true,"identifiers":{"issn":["0305-182X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:185, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10029463","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249990","label":"url"}],"paper_title":{"en":"Clinical predictability of temporomandibular joint disc displacement.","ja":"Clinical predictability of temporomandibular joint disc displacement."},"authors":{"en":[{"name":"Orsini M G"},{"name":"Kuboki T"},{"name":"Terada S"},{"name":"Matsuka Yoshizo"},{"name":"Yatani H"},{"name":"Yamashita A"}],"ja":[{"name":"Orsini M G"},{"name":"Kuboki T"},{"name":"Terada S"},{"name":"松香 芳三"},{"name":"Yatani H"},{"name":"Yamashita A"}]},"description":{"en":"Single items from a typical clinical examination have proved disappointing in their predictive value for temporomandibular joint (TMJ) disc displacement. Only one criterion (the 12 o'clock) is used to diagnose normal disc position. According to this criterion, the posterior band of the disc should be located at the top of the condyle, at the 12 o'clock position. The purpose of this study was to determine which signs and symptoms provide a valid prediction of the condition of the joint based on 4 magnetic resonance imaging (MRI) criteria used to define normal disc position. Sagittal MRI and clinical findings of 137 temporomandibular disorder patients and 23 normal asymptomatic volunteers were used. Three calibrated and blinded observers interpreted the images. Disc position with the mouth closed was evaluated based on 4 MRI criteria: 12, 11, 10 o'clock, and the intermediate zone. Disc position with the mouth open was determined based on one criterion. It was considered normal if the intermediate zone of the disc was located between the condyle and the articular eminence. Joints were classified as normal or as having disc displacement with or without reduction. The sensitivity and specificity of multiple clinical parameters for predicting the condition of the joint established by each of these 4 gold-standard MRI criteria were then determined. Regarding disc displacement with reduction, significant differences were observed in the sensitivity and specificity of all of the clinical parameters used to predict the imaging diagnosis established by each of the criteria. Concerning disc displacement without reduction, no significant differences were observed. The intermediate zone criterion was the criterion that most accurately reflected the condition of the joint. The clinical predictability of the disorder diagnosed according to this criterion suggests that clinical findings alone are too often nonspecific as predictors of the imaging stage of disc displacement. However, we found that combining the most sensitive clinical items to predict the disorder and using an overall criterion for positivity to interpret the results led to an impressive increase in the specificity of the combination, enabling false-positive diagnoses to be excluded.","ja":"Single items from a typical clinical examination have proved disappointing in their predictive value for temporomandibular joint (TMJ) disc displacement. Only one criterion (the 12 o'clock) is used to diagnose normal disc position. According to this criterion, the posterior band of the disc should be located at the top of the condyle, at the 12 o'clock position. The purpose of this study was to determine which signs and symptoms provide a valid prediction of the condition of the joint based on 4 magnetic resonance imaging (MRI) criteria used to define normal disc position. Sagittal MRI and clinical findings of 137 temporomandibular disorder patients and 23 normal asymptomatic volunteers were used. Three calibrated and blinded observers interpreted the images. Disc position with the mouth closed was evaluated based on 4 MRI criteria: 12, 11, 10 o'clock, and the intermediate zone. Disc position with the mouth open was determined based on one criterion. It was considered normal if the intermediate zone of the disc was located between the condyle and the articular eminence. Joints were classified as normal or as having disc displacement with or without reduction. The sensitivity and specificity of multiple clinical parameters for predicting the condition of the joint established by each of these 4 gold-standard MRI criteria were then determined. Regarding disc displacement with reduction, significant differences were observed in the sensitivity and specificity of all of the clinical parameters used to predict the imaging diagnosis established by each of the criteria. Concerning disc displacement without reduction, no significant differences were observed. The intermediate zone criterion was the criterion that most accurately reflected the condition of the joint. The clinical predictability of the disorder diagnosed according to this criterion suggests that clinical findings alone are too often nonspecific as predictors of the imaging stage of disc displacement. However, we found that combining the most sensitive clinical items to predict the disorder and using an overall criterion for positivity to interpret the results led to an impressive increase in the specificity of the combination, enabling false-positive diagnoses to be excluded."},"publication_date":"1999-02","publication_name":{"en":"Journal of Dental Research","ja":"Journal of Dental Research"},"volume":"Vol.78","number":"No.2","starting_page":"650","ending_page":"660","languages":["eng"],"referee":true,"identifiers":{"issn":["0022-0345"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:186, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250034","label":"url"}],"paper_title":{"en":"口腔顔面慢性疼痛に対する塩酸アミトリプチリンの鎮痛効果ならびに副作用","ja":"口腔顔面慢性疼痛に対する塩酸アミトリプチリンの鎮痛効果ならびに副作用"},"authors":{"en":[{"name":"満木 志おり"},{"name":"前川 賢治"},{"name":"水口 一"},{"name":"窪木 拓男"},{"name":"Matsuka Yoshizo"},{"name":"山下 敦"}],"ja":[{"name":"満木 志おり"},{"name":"前川 賢治"},{"name":"水口 一"},{"name":"窪木 拓男"},{"name":"松香 芳三"},{"name":"山下 敦"}]},"publication_date":"1999","publication_name":{"en":"The Journal of the Japan Prosthodontic Society","ja":"日本補綴歯科学会雑誌"},"volume":"Vol.43","number":"No.3","starting_page":"451","ending_page":"456","languages":["jpn"],"referee":true,"identifiers":{"issn":["0389-5386"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:187, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250033","label":"url"}],"paper_title":{"en":"顎関節症類似の症状を呈した間代性神経障害性疼痛 血中カルバマゼピン濃度測定","ja":"顎関節症類似の症状を呈した間代性神経障害性疼痛 血中カルバマゼピン濃度測定"},"authors":{"en":[{"name":"小島 俊司"},{"name":"窪木 拓男"},{"name":"古野 勝志"},{"name":"Matsuka Yoshizo"},{"name":"前川 賢治"},{"name":"助政 安伸"},{"name":"上原 淳二"},{"name":"矢谷 博文"},{"name":"山下 敦"}],"ja":[{"name":"小島 俊司"},{"name":"窪木 拓男"},{"name":"古野 勝志"},{"name":"松香 芳三"},{"name":"前川 賢治"},{"name":"助政 安伸"},{"name":"上原 淳二"},{"name":"矢谷 博文"},{"name":"山下 敦"}]},"publication_date":"1999","publication_name":{"en":"The Journal of the Japan Prosthodontic Society","ja":"日本補綴歯科学会雑誌"},"volume":"Vol.43","number":"No.6","starting_page":"977","ending_page":"982","languages":["jpn"],"referee":true,"identifiers":{"issn":["0389-5386"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:188, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250032","label":"url"}],"paper_title":{"en":"歯科治療に関連して発症した持続性神経障害性疼痛 非定型性歯痛","ja":"歯科治療に関連して発症した持続性神経障害性疼痛 非定型性歯痛"},"authors":{"en":[{"name":"窪木 拓男"},{"name":"井上 真実"},{"name":"古野 勝志"},{"name":"Matsuka Yoshizo"},{"name":"前川 賢治"},{"name":"矢谷 博文"},{"name":"山下 敦"}],"ja":[{"name":"窪木 拓男"},{"name":"井上 真実"},{"name":"古野 勝志"},{"name":"松香 芳三"},{"name":"前川 賢治"},{"name":"矢谷 博文"},{"name":"山下 敦"}]},"publication_date":"1999","publication_name":{"en":"The Journal of the Japan Prosthodontic Society","ja":"日本補綴歯科学会雑誌"},"volume":"Vol.43","number":"No.6","starting_page":"970","ending_page":"976","languages":["jpn"],"referee":true,"identifiers":{"issn":["0389-5386"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:189, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250031","label":"url"}],"paper_title":{"en":"いびきに関する文献的考察","ja":"いびきに関する文献的考察"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"木庭 茂治"},{"name":"矢谷 博文"}],"ja":[{"name":"松香 芳三"},{"name":"木庭 茂治"},{"name":"矢谷 博文"}]},"publication_date":"1999","publication_name":{"en":"The Journal of the Japan Association of Cranio-Mandibular Orthopedics","ja":"日本顎頭蓋機能学会誌"},"volume":"Vol.12","number":"No.1","starting_page":"19","ending_page":"26","languages":["jpn"],"referee":true,"identifiers":{"issn":["1340-8852"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:190, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/9798238","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249991","label":"url"}],"paper_title":{"en":"Diagnostic value of 4 criteria to interpret temporomandibular joint normal disk position on magnetic resonance images.","ja":"Diagnostic value of 4 criteria to interpret temporomandibular joint normal disk position on magnetic resonance images."},"authors":{"en":[{"name":"Orsini M G"},{"name":"Kuboki T"},{"name":"Terada S"},{"name":"Matsuka Yoshizo"},{"name":"Yamashita A"},{"name":"Clark G T"}],"ja":[{"name":"Orsini M G"},{"name":"Kuboki T"},{"name":"Terada S"},{"name":"松香 芳三"},{"name":"Yamashita A"},{"name":"Clark G T"}]},"description":{"en":"These results suggest that the intermediate zone criterion for disk displacement is the more stringent criterion and the one that would yield the lowest number of false positives when the disk position is being judged in the closed-mouth sagittal view.","ja":"These results suggest that the intermediate zone criterion for disk displacement is the more stringent criterion and the one that would yield the lowest number of false positives when the disk position is being judged in the closed-mouth sagittal view."},"publication_date":"1998-10","publication_name":{"en":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics","ja":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics"},"volume":"Vol.86","number":"No.4","starting_page":"489","ending_page":"497","languages":["eng"],"referee":true,"identifiers":{"issn":["1079-2104"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:191, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/9758399","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249992","label":"url"}],"paper_title":{"en":"Macroscopic osseous changes in the temporomandibular joint related to dental attrition in Japanese macaque skull.","ja":"Macroscopic osseous changes in the temporomandibular joint related to dental attrition in Japanese macaque skull."},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Iijima T"},{"name":"Suzuki K"},{"name":"Kuboki T"},{"name":"Yamashita A"}],"ja":[{"name":"松香 芳三"},{"name":"Iijima T"},{"name":"Suzuki K"},{"name":"Kuboki T"},{"name":"Yamashita A"}]},"description":{"en":"The purpose of this study was to investigate the relationship between osseous changes in the temporomandibular joint (TMJ) and dental attrition in the Japanese macaque. One hundred and thirty Japanese macaque skulls (54 male and 76 female) from animals which had been bred in the same environment, were randomly sampled from a collection at the Primate Research Institute of Kyoto University. The age at death had been recorded in all cases. TMJ osseous changes were independently evaluated by three examiners, and were defined as an irregular surface or a perforated compact bone layer with a markedly irregular surface on either the temporal or condylar components. Age was a significant factor in predicting TMJ osseous changes (P < 0.001). A strong relation was observed between age and dental attrition (P < 0.001), while dental attrition was not a significant factor in predicting TMJ osseous changes (P = 0.334). The prevalence TMJ osseous changes in male animals was slightly higher than in females (P = 0.057). The results of this study suggest that osseous changes in the macaque TMJ are mainly related to age, not to dental attrition.","ja":"The purpose of this study was to investigate the relationship between osseous changes in the temporomandibular joint (TMJ) and dental attrition in the Japanese macaque. One hundred and thirty Japanese macaque skulls (54 male and 76 female) from animals which had been bred in the same environment, were randomly sampled from a collection at the Primate Research Institute of Kyoto University. The age at death had been recorded in all cases. TMJ osseous changes were independently evaluated by three examiners, and were defined as an irregular surface or a perforated compact bone layer with a markedly irregular surface on either the temporal or condylar components. Age was a significant factor in predicting TMJ osseous changes (P < 0.001). A strong relation was observed between age and dental attrition (P < 0.001), while dental attrition was not a significant factor in predicting TMJ osseous changes (P = 0.334). The prevalence TMJ osseous changes in male animals was slightly higher than in females (P = 0.057). The results of this study suggest that osseous changes in the macaque TMJ are mainly related to age, not to dental attrition."},"publication_date":"1998-09","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.25","number":"No.9","starting_page":"687","ending_page":"693","languages":["eng"],"referee":true,"identifiers":{"issn":["0305-182X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:192, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/9638696","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249996","label":"url"}],"paper_title":{"en":"The validity of clinical examination for diagnosing anterior disk displacement with reduction.","ja":"The validity of clinical examination for diagnosing anterior disk displacement with reduction."},"authors":{"en":[{"name":"Yatani H"},{"name":"Sonoyama W"},{"name":"Kuboki T"},{"name":"Matsuka Yoshizo"},{"name":"Orsini M G"},{"name":"Yamashita A"}],"ja":[{"name":"Yatani H"},{"name":"Sonoyama W"},{"name":"Kuboki T"},{"name":"松香 芳三"},{"name":"Orsini M G"},{"name":"Yamashita A"}]},"description":{"en":"Our results suggest that anterior disk displacement with reduction can be diagnosed with considerable accuracy through the use of a clinical examination only.","ja":"Our results suggest that anterior disk displacement with reduction can be diagnosed with considerable accuracy through the use of a clinical examination only."},"publication_date":"1998-06","publication_name":{"en":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics","ja":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics"},"volume":"Vol.85","number":"No.6","starting_page":"647","ending_page":"653","languages":["eng"],"referee":true,"identifiers":{"issn":["1079-2104"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:193, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/9638697","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249995","label":"url"}],"paper_title":{"en":"The validity of clinical examination for diagnosing anterior disk displacement without reduction.","ja":"The validity of clinical examination for diagnosing anterior disk displacement without reduction."},"authors":{"en":[{"name":"Yatani H"},{"name":"Suzuki K"},{"name":"Kuboki T"},{"name":"Matsuka Yoshizo"},{"name":"Maekawa K"},{"name":"Yamashita A"}],"ja":[{"name":"Yatani H"},{"name":"Suzuki K"},{"name":"Kuboki T"},{"name":"松香 芳三"},{"name":"Maekawa K"},{"name":"Yamashita A"}]},"description":{"en":"Our results suggest that the predictability of historical or clinical findings to differentiate anterior disk displacement without reduction from other diagnoses is not high.","ja":"Our results suggest that the predictability of historical or clinical findings to differentiate anterior disk displacement without reduction from other diagnoses is not high."},"publication_date":"1998-06","publication_name":{"en":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics","ja":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics"},"volume":"Vol.85","number":"No.6","starting_page":"654","ending_page":"660","languages":["eng"],"referee":true,"identifiers":{"issn":["1079-2104"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:194, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/9687112","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249993","label":"url"}],"paper_title":{"en":"The relationship between signs and symptoms of temporomandibular disorders and bilateral occlusal contact patterns during lateral excursions.","ja":"The relationship between signs and symptoms of temporomandibular disorders and bilateral occlusal contact patterns during lateral excursions."},"authors":{"en":[{"name":"Watanabe E K"},{"name":"Yatani H"},{"name":"Kuboki T"},{"name":"Matsuka Yoshizo"},{"name":"Terada S"},{"name":"Orsini M G"},{"name":"Yamashita A"}],"ja":[{"name":"Watanabe E K"},{"name":"Yatani H"},{"name":"Kuboki T"},{"name":"松香 芳三"},{"name":"Terada S"},{"name":"Orsini M G"},{"name":"Yamashita A"}]},"description":{"en":"The relationship between signs and symptoms of temporomandibular disorders (TMD) and bilateral occlusal contact patterns was investigated in 143 TMD patients (mean age: 34.0 +/- 15.9 years; 38 male and 105 female). In addition to an interview regarding chief complaints and accompanying symptoms, various muscles and the temporomandibular joints were palpated bilaterally and occlusal analyses were made. Only 5 out of 108 paired variables were found to be significantly associated by using the chi-squared test. Medial pterygoid muscle pain on palpation showed significant associations with the occlusal contact pattern (P < 0.005), especially working side contacts (interocclusal tooth contacts on the working side) (P < 0.005), during contralateral excursions; sternocleidomastoid muscle pain on palpation showed a significant association with balancing side contacts (interocclusal tooth contacts on the balancing side) during ipsilateral excursions P < 0.05); shoulder stiffness and pain in the eye showed significant associations with balancing side contacts during contralateral excursions (P < 0.05). The results show only a weak relationship between some TMD symptomatology and bilateral occlusal contact patterns during lateral excursions. The findings suggesting the specific laterality of a few TMD signs and symptoms associated with particular occlusal contacts may deserve closer case-control study.","ja":"The relationship between signs and symptoms of temporomandibular disorders (TMD) and bilateral occlusal contact patterns was investigated in 143 TMD patients (mean age: 34.0 +/- 15.9 years; 38 male and 105 female). In addition to an interview regarding chief complaints and accompanying symptoms, various muscles and the temporomandibular joints were palpated bilaterally and occlusal analyses were made. Only 5 out of 108 paired variables were found to be significantly associated by using the chi-squared test. Medial pterygoid muscle pain on palpation showed significant associations with the occlusal contact pattern (P < 0.005), especially working side contacts (interocclusal tooth contacts on the working side) (P < 0.005), during contralateral excursions; sternocleidomastoid muscle pain on palpation showed a significant association with balancing side contacts (interocclusal tooth contacts on the balancing side) during ipsilateral excursions P < 0.05); shoulder stiffness and pain in the eye showed significant associations with balancing side contacts during contralateral excursions (P < 0.05). The results show only a weak relationship between some TMD symptomatology and bilateral occlusal contact patterns during lateral excursions. The findings suggesting the specific laterality of a few TMD signs and symptoms associated with particular occlusal contacts may deserve closer case-control study."},"publication_date":"1998-06","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.25","number":"No.6","starting_page":"409","ending_page":"415","languages":["eng"],"referee":true,"identifiers":{"issn":["0305-182X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:195, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/9576602","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249997","label":"url"}],"paper_title":{"en":"Effects of a bite-raising splint on the duration of the chewing cycle and the EMG activities of masticatory muscles during chewing in freely moving rabbits.","ja":"Effects of a bite-raising splint on the duration of the chewing cycle and the EMG activities of masticatory muscles during chewing in freely moving rabbits."},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Kitada Y"},{"name":"Mitoh Y"},{"name":"Adachi A"},{"name":"Yamashita A"}],"ja":[{"name":"松香 芳三"},{"name":"Kitada Y"},{"name":"Mitoh Y"},{"name":"Adachi A"},{"name":"Yamashita A"}]},"description":{"en":"Metal bite-raising splints of 0.5 mm thickness were attached to the upper molar teeth on both sides of the jaw in rabbits. The effects of these splints on masticatory behaviour during the chewing of soft food (bread) by freely moving rabbits were investigated. We recorded electromyograms (EMGs) of the masseter and digastric muscles. The animals exhibited prolongation of the chewing cycle, decreased EMG activity of the masseter muscle and increased EMG activity of the digastric muscle during chewing after introduction of the bite-raising splints. The effects of the splints on the activities of masticatory muscles were abolished by bilateral sectioning of the maxillary and inferior alveolar nerves. It seems likely that afferents from oral sensory receptors were responsible for the changes in masticatory behaviour after the introduction of the occlusal splint.","ja":"Metal bite-raising splints of 0.5 mm thickness were attached to the upper molar teeth on both sides of the jaw in rabbits. The effects of these splints on masticatory behaviour during the chewing of soft food (bread) by freely moving rabbits were investigated. We recorded electromyograms (EMGs) of the masseter and digastric muscles. The animals exhibited prolongation of the chewing cycle, decreased EMG activity of the masseter muscle and increased EMG activity of the digastric muscle during chewing after introduction of the bite-raising splints. The effects of the splints on the activities of masticatory muscles were abolished by bilateral sectioning of the maxillary and inferior alveolar nerves. It seems likely that afferents from oral sensory receptors were responsible for the changes in masticatory behaviour after the introduction of the occlusal splint."},"publication_date":"1998-02","publication_name":{"en":"Journal of Oral Rehabilitation","ja":"Journal of Oral Rehabilitation"},"volume":"Vol.25","number":"No.2","starting_page":"159","ending_page":"165","languages":["eng"],"referee":true,"identifiers":{"issn":["0305-182X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:196, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797155"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250036","label":"url"}],"paper_title":{"en":"顎顔面疼痛患者に対する治療法(第1報) 頭痛の診断","ja":"顎顔面疼痛患者に対する治療法(第1報) 頭痛の診断"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"MerrillRobert L."},{"name":"Urbach Abraham"},{"name":"窪木 拓男"},{"name":"矢谷 博文"},{"name":"山下 敦"}],"ja":[{"name":"松香 芳三"},{"name":"MerrillRobert L."},{"name":"Urbach Abraham"},{"name":"窪木 拓男"},{"name":"矢谷 博文"},{"name":"山下 敦"}]},"publication_date":"1998","publication_name":{"en":"The Journal of the Japan Association of Cranio-Mandibular Orthopedics","ja":"日本顎頭蓋機能学会誌"},"volume":"Vol.11","number":"No.1","starting_page":"11","ending_page":"18","languages":["jpn"],"referee":true,"identifiers":{"issn":["1340-8852"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:197, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797156"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250035","label":"url"}],"paper_title":{"en":"顎顔面疼痛患者に対する治療法(第2報) 頭痛の治療","ja":"顎顔面疼痛患者に対する治療法(第2報) 頭痛の治療"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"MerrillRobert L."},{"name":"窪木 拓男"},{"name":"矢谷 博文"},{"name":"山下 敦"}],"ja":[{"name":"松香 芳三"},{"name":"MerrillRobert L."},{"name":"窪木 拓男"},{"name":"矢谷 博文"},{"name":"山下 敦"}]},"publication_date":"1998","publication_name":{"en":"The Journal of the Japan Association of Cranio-Mandibular Orthopedics","ja":"日本顎頭蓋機能学会誌"},"volume":"Vol.11","number":"No.1","starting_page":"19","ending_page":"27","languages":["jpn"],"referee":true,"identifiers":{"issn":["1340-8852"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:198, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/9656902","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249994","label":"url"}],"paper_title":{"en":"The long-term effect of occlusal therapy on self-administered treatment outcomes of TMD.","ja":"The long-term effect of occlusal therapy on self-administered treatment outcomes of TMD."},"authors":{"en":[{"name":"Yatani H"},{"name":"Minakuchi H"},{"name":"Matsuka Yoshizo"},{"name":"Fujisawa T"},{"name":"Yamashita A"}],"ja":[{"name":"Yatani H"},{"name":"Minakuchi H"},{"name":"松香 芳三"},{"name":"Fujisawa T"},{"name":"Yamashita A"}]},"description":{"en":"Because of a lack of substantial scientific data, the efficacy of occlusal therapy for the management of temporomandibular disorders (TMD) is still controversial. Of a total of 1405 consecutive TMD patients examined over the last 10 years, 369 (26.3%) were determined to have completed treatment at least 1 year before the present survey. A sample questionnaire was mailed to each patient in this sample population. The questionnaire failed to reach 46 patients; of the 323 patients who received the questionnaire, 260 (80.5%) responded. The mean duration of time between their last visit and this survey was 3.7 years. The questionnaire elicited information on treatment outcomes, present treatment needs, and current signs and symptoms. Participants were divided into two treatment groups: (a) those who underwent some occlusal therapies (Phase II) following successful reversible therapies (Phase I) (20 men and 114 women); and (b) those who underwent reversible therapy only (33 men and 93 women). Participants were further differentially diagnosed into five diagnostic subgroups of TMD, based on the clinical examination at the initial visit, tomography, and, for some patients, magnetic resonance imaging. The subgroups included myalgia, arthralgia, anterior disc displacement with an without reduction, and osteoarthritis/osteoarthrosis. Only 12.3% of the total population surveyed reported lack of improvement to an acceptable level and further need for treatment. The remaining patients reported satisfactory results in the reduction of TMD symptomatology and no further need for treatment, because their symptoms had either disappeared or improved to an acceptable level. Regardless of treatment groups and diagnostic subgroups, the current subjective signs and symptoms were negligible in most patients, and mean mouth openings were in the normal range. No particular diagnostic subgroups seemed to have significantly better outcome following Phase II occlusal therapy. These results suggest that the majority of TMD signs and symptoms improve to an acceptable level with only reversible therapy, and the long-term value of additional occlusal therapy following reversible therapy is minimal. Therefore, permanent occlusion-changing therapies apparently are not generally needed to maintain TMD symptom reduction over time.","ja":"Because of a lack of substantial scientific data, the efficacy of occlusal therapy for the management of temporomandibular disorders (TMD) is still controversial. Of a total of 1405 consecutive TMD patients examined over the last 10 years, 369 (26.3%) were determined to have completed treatment at least 1 year before the present survey. A sample questionnaire was mailed to each patient in this sample population. The questionnaire failed to reach 46 patients; of the 323 patients who received the questionnaire, 260 (80.5%) responded. The mean duration of time between their last visit and this survey was 3.7 years. The questionnaire elicited information on treatment outcomes, present treatment needs, and current signs and symptoms. Participants were divided into two treatment groups: (a) those who underwent some occlusal therapies (Phase II) following successful reversible therapies (Phase I) (20 men and 114 women); and (b) those who underwent reversible therapy only (33 men and 93 women). Participants were further differentially diagnosed into five diagnostic subgroups of TMD, based on the clinical examination at the initial visit, tomography, and, for some patients, magnetic resonance imaging. The subgroups included myalgia, arthralgia, anterior disc displacement with an without reduction, and osteoarthritis/osteoarthrosis. Only 12.3% of the total population surveyed reported lack of improvement to an acceptable level and further need for treatment. The remaining patients reported satisfactory results in the reduction of TMD symptomatology and no further need for treatment, because their symptoms had either disappeared or improved to an acceptable level. Regardless of treatment groups and diagnostic subgroups, the current subjective signs and symptoms were negligible in most patients, and mean mouth openings were in the normal range. No particular diagnostic subgroups seemed to have significantly better outcome following Phase II occlusal therapy. These results suggest that the majority of TMD signs and symptoms improve to an acceptable level with only reversible therapy, and the long-term value of additional occlusal therapy following reversible therapy is minimal. Therefore, permanent occlusion-changing therapies apparently are not generally needed to maintain TMD symptom reduction over time."},"publication_date":"1998","publication_name":{"en":"Journal of Orofacial Pain","ja":"Journal of Orofacial Pain"},"volume":"Vol.12","number":"No.1","starting_page":"75","ending_page":"88","languages":["eng"],"referee":true,"identifiers":{"issn":["1064-6655"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:199, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/9247957","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249999","label":"url"}],"paper_title":{"en":"The influence of observer calibration in temporomandibular joint magnetic resonance imaging diagnosis.","ja":"The influence of observer calibration in temporomandibular joint magnetic resonance imaging diagnosis."},"authors":{"en":[{"name":"Orsini M G"},{"name":"Terada S"},{"name":"Kuboki T"},{"name":"Matsuka Yoshizo"},{"name":"Yamashita A"}],"ja":[{"name":"Orsini M G"},{"name":"Terada S"},{"name":"Kuboki T"},{"name":"松香 芳三"},{"name":"Yamashita A"}]},"description":{"en":"These data suggest that after calibration trials, it is possible for three examiners to obtain reliable and reproducible results in reporting temporomandibular joint disk position on magnetic resonance images.","ja":"These data suggest that after calibration trials, it is possible for three examiners to obtain reliable and reproducible results in reporting temporomandibular joint disk position on magnetic resonance images."},"publication_date":"1997-07","publication_name":{"en":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics","ja":"Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics"},"volume":"Vol.84","number":"No.1","starting_page":"82","ending_page":"87","languages":["eng"],"referee":true,"identifiers":{"issn":["1079-2104"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:200, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797159"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=251347","label":"url"}],"paper_title":{"en":"質問表を用いた咬合処置の有効性に関する顎関節内障患者の遠隔予後調査","ja":"質問表を用いた咬合処置の有効性に関する顎関節内障患者の遠隔予後調査"},"authors":{"en":[{"name":"水口 一"},{"name":"矢谷 博文"},{"name":"山下 敦"},{"name":"窪木 拓男"},{"name":"Matsuka Yoshizo"}],"ja":[{"name":"水口 一"},{"name":"矢谷 博文"},{"name":"山下 敦"},{"name":"窪木 拓男"},{"name":"松香 芳三"}]},"publication_date":"1997","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.9","number":"No.2","starting_page":"397","ending_page":"409","languages":["jpn"],"referee":true,"identifiers":{"issn":["0915-3004"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:201, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797160"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250038","label":"url"}],"paper_title":{"en":"疫学研究に用いるための顎関節症症状に関する質問表の妥当性","ja":"疫学研究に用いるための顎関節症症状に関する質問表の妥当性"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"伊藤 真午"},{"name":"水口 一"},{"name":"窪木 拓男"},{"name":"山下 敦"}],"ja":[{"name":"松香 芳三"},{"name":"伊藤 真午"},{"name":"水口 一"},{"name":"窪木 拓男"},{"name":"山下 敦"}]},"publication_date":"1997","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.9","number":"No.1","starting_page":"80","ending_page":"91","languages":["jpn"],"referee":true,"identifiers":{"issn":["0915-3004"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:202, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250037","label":"url"}],"paper_title":{"en":"質問表を用いた顎関節症の咬合治療に関する遠隔予後調査(第1報) 顎関節症患者全体における咬合治療の有効性","ja":"質問表を用いた顎関節症の咬合治療に関する遠隔予後調査(第1報) 顎関節症患者全体における咬合治療の有効性"},"authors":{"en":[{"name":"水口 一"},{"name":"窪木 拓男"},{"name":"Matsuka Yoshizo"},{"name":"矢谷 博文"},{"name":"山下 敦"}],"ja":[{"name":"水口 一"},{"name":"窪木 拓男"},{"name":"松香 芳三"},{"name":"矢谷 博文"},{"name":"山下 敦"}]},"publication_date":"1997","publication_name":{"en":"The Journal of the Japan Prosthodontic Society","ja":"日本補綴歯科学会雑誌"},"volume":"Vol.41","number":"No.4","starting_page":"552","ending_page":"559","languages":["jpn"],"referee":true,"identifiers":{"issn":["0389-5386"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:203, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/9610316","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=249998","label":"url"}],"paper_title":{"en":"Long-term follow-up study on drop-out TMD patients with self-administered questionnaires.","ja":"Long-term follow-up study on drop-out TMD patients with self-administered questionnaires."},"authors":{"en":[{"name":"Yatani H"},{"name":"Kaneshima T"},{"name":"Kuboki T"},{"name":"Yoshimoto A"},{"name":"Matsuka Yoshizo"},{"name":"Yamashita A"}],"ja":[{"name":"Yatani H"},{"name":"Kaneshima T"},{"name":"Kuboki T"},{"name":"Yoshimoto A"},{"name":"松香 芳三"},{"name":"Yamashita A"}]},"description":{"en":"Although patient attrition might be a serious threat to the validity of treatment-outcome studies on temporomandibular disorders (TMD), studies on TMD patient attrition are scarce. Of the 1405 consecutive TMD patients examined in a recent 10-year period, 367 (26.1%) drop-out patients or patients identified with a control group were sampled. A mailed questionnaire failed to reach 41 patients, and 203 (62.3%) were returned. The questionnaire elicited information on reasons for dropping out, changes in symptoms, treatment received in other clinics after dropping out, present treatment needs, and current signs and symptoms. Dropouts were divided into two groups: (1) those who failed to show up for their first scheduled appointment after the clinical examination; (2) those who failed to complete treatment. A group of patients who were judged by the examiner not to need treatment were included as a control group. The main reasons for dropping out were environmental obstacles, perceived improvement of the disease, and dissatisfaction with services. Only 21.7% considered themselves to be in need of treatment, and only 10.3% had visited other clinics after dropping out. Only 8.9% complained of the continued aggravation of symptoms, whereas 57.6% reported improvement. In addition, pain, dysfunction, and daily activity limitation tended to improve with time, although temporomandibular joint noise tended to persist. These results suggest that TMD signs and symptoms tend to decrease in patients after dropping out, and that the natural fluctuation of TMD signs and symptoms should be taken into consideration when treating TMD.","ja":"Although patient attrition might be a serious threat to the validity of treatment-outcome studies on temporomandibular disorders (TMD), studies on TMD patient attrition are scarce. Of the 1405 consecutive TMD patients examined in a recent 10-year period, 367 (26.1%) drop-out patients or patients identified with a control group were sampled. A mailed questionnaire failed to reach 41 patients, and 203 (62.3%) were returned. The questionnaire elicited information on reasons for dropping out, changes in symptoms, treatment received in other clinics after dropping out, present treatment needs, and current signs and symptoms. Dropouts were divided into two groups: (1) those who failed to show up for their first scheduled appointment after the clinical examination; (2) those who failed to complete treatment. A group of patients who were judged by the examiner not to need treatment were included as a control group. The main reasons for dropping out were environmental obstacles, perceived improvement of the disease, and dissatisfaction with services. Only 21.7% considered themselves to be in need of treatment, and only 10.3% had visited other clinics after dropping out. Only 8.9% complained of the continued aggravation of symptoms, whereas 57.6% reported improvement. In addition, pain, dysfunction, and daily activity limitation tended to improve with time, although temporomandibular joint noise tended to persist. These results suggest that TMD signs and symptoms tend to decrease in patients after dropping out, and that the natural fluctuation of TMD signs and symptoms should be taken into consideration when treating TMD."},"publication_date":"1997","publication_name":{"en":"Journal of Orofacial Pain","ja":"Journal of Orofacial Pain"},"volume":"Vol.11","number":"No.3","starting_page":"258","ending_page":"269","languages":["eng"],"referee":true,"identifiers":{"issn":["1064-6655"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:204, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/8949871","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250000","label":"url"}],"paper_title":{"en":"Temporomandibular disorders in the adult population of Okayama City, Japan.","ja":"Temporomandibular disorders in the adult population of Okayama City, Japan."},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"Yatani H"},{"name":"Kuboki T"},{"name":"Yamashita A"}],"ja":[{"name":"松香 芳三"},{"name":"Yatani H"},{"name":"Kuboki T"},{"name":"Yamashita A"}]},"description":{"en":"In order to discover the prevalence of signs and symptoms of temporomandibular disorders (TMD) in Japan, and the difference in the prevalence among various sex and age groups in the Japanese population, 672 individuals (304 males and 368 females, age range 20-92 years) were selected randomly in Okayama City, Japan, and were investigated by means of questionnaires and clinical examinations. The reported frequency of symptoms was: TMJ sounds 24%, facial-TMJ-jaw pain 11%, headache 27%, teeth clenching 30%, and grinding 34%. The percent frequency of the following signs was: impaired mouth opening 5%, clicking 46%, reciprocal clicking 20%, crepitus 19%, TMJ tenderness 6%, and masticatory muscle tenderness 21%. The subjects with TMJ clicking were more frequently females than males. TMD signs and symptoms were found to be common in all age groups, but they were fewer in the older than in the younger age group. The younger-aged subjects with clicking appeared with significant frequency, whereas crepitus was populated with significant frequency by the oldest age group.","ja":"In order to discover the prevalence of signs and symptoms of temporomandibular disorders (TMD) in Japan, and the difference in the prevalence among various sex and age groups in the Japanese population, 672 individuals (304 males and 368 females, age range 20-92 years) were selected randomly in Okayama City, Japan, and were investigated by means of questionnaires and clinical examinations. The reported frequency of symptoms was: TMJ sounds 24%, facial-TMJ-jaw pain 11%, headache 27%, teeth clenching 30%, and grinding 34%. The percent frequency of the following signs was: impaired mouth opening 5%, clicking 46%, reciprocal clicking 20%, crepitus 19%, TMJ tenderness 6%, and masticatory muscle tenderness 21%. The subjects with TMJ clicking were more frequently females than males. TMD signs and symptoms were found to be common in all age groups, but they were fewer in the older than in the younger age group. The younger-aged subjects with clicking appeared with significant frequency, whereas crepitus was populated with significant frequency by the oldest age group."},"publication_date":"1996-04","publication_name":{"en":"Cranio","ja":"Cranio"},"volume":"Vol.14","number":"No.2","starting_page":"158","ending_page":"162","languages":["eng"],"referee":true,"identifiers":{"issn":["0886-9634"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:205, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797164"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250042","label":"url"}],"paper_title":{"en":"咀嚼筋痛と頭頸背部慢性疼痛との関連に関する疫学調査","ja":"咀嚼筋痛と頭頸背部慢性疼痛との関連に関する疫学調査"},"authors":{"en":[{"name":"辻清 薫"},{"name":"山下 敦"},{"name":"Matsuka Yoshizo"},{"name":"窪木 拓男"},{"name":"矢谷 博文"}],"ja":[{"name":"辻清 薫"},{"name":"山下 敦"},{"name":"松香 芳三"},{"name":"窪木 拓男"},{"name":"矢谷 博文"}]},"publication_date":"1996","publication_name":{"en":"The Journal of the Japan Association of Cranio-Mandibular Orthopedics","ja":"日本顎頭蓋機能学会誌"},"volume":"Vol.9","number":"No.1","starting_page":"31","ending_page":"39","languages":["jpn"],"referee":true,"identifiers":{"issn":["1340-8852"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:206, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797165"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250039","label":"url"}],"paper_title":{"en":"頭頸部慢性疼痛に対する三環系抗うつ剤の鎮痛効果ならびに副作用","ja":"頭頸部慢性疼痛に対する三環系抗うつ剤の鎮痛効果ならびに副作用"},"authors":{"en":[{"name":"窪木 拓男"},{"name":"山下 敦"},{"name":"Matsuka Yoshizo"},{"name":"満木 志おり"}],"ja":[{"name":"窪木 拓男"},{"name":"山下 敦"},{"name":"松香 芳三"},{"name":"満木 志おり"}]},"publication_date":"1996","publication_name":{"en":"The Journal of the Japan Association of Cranio-Mandibular Orthopedics","ja":"日本顎頭蓋機能学会誌"},"volume":"Vol.9","number":"No.1","starting_page":"11","ending_page":"23","languages":["jpn"],"referee":true,"identifiers":{"issn":["1340-8852"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:207, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250043","label":"url"}],"paper_title":{"en":"顎関節症の病型分類による疫学的研究 有症群の解析","ja":"顎関節症の病型分類による疫学的研究 有症群の解析"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"矢谷 博文"},{"name":"山下 敦"}],"ja":[{"name":"松香 芳三"},{"name":"矢谷 博文"},{"name":"山下 敦"}]},"publication_date":"1994","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.6","number":"No.1","starting_page":"13","ending_page":"24","languages":["jpn"],"referee":true,"identifiers":{"issn":["0915-3004"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:208, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797167"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250045","label":"url"}],"paper_title":{"en":"顎関節症の症型分類による疫学的研究(第1編)臨床的分類による症型別発症頻度","ja":"顎関節症の症型分類による疫学的研究(第1編)臨床的分類による症型別発症頻度"},"authors":{"en":[{"name":"Matsuka Yoshizo"}],"ja":[{"name":"松香 芳三"}]},"publication_date":"1992","publication_name":{"en":"The Journal of Okayama Dental Society","ja":"岡山歯学会雑誌"},"volume":"Vol.11","number":"No.1","starting_page":"73","ending_page":"89","languages":["jpn"],"referee":true,"identifiers":{"issn":["0913-3941"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:209, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797168"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250044","label":"url"}],"paper_title":{"en":"顎関節症の症型分類による疫学的研究(第2編)臨床的分類による症型別発症要因の予測","ja":"顎関節症の症型分類による疫学的研究(第2編)臨床的分類による症型別発症要因の予測"},"authors":{"en":[{"name":"Matsuka Yoshizo"}],"ja":[{"name":"松香 芳三"}]},"publication_date":"1992","publication_name":{"en":"The Journal of Okayama Dental Society","ja":"岡山歯学会雑誌"},"volume":"Vol.11","number":"No.1","starting_page":"91","ending_page":"105","languages":["jpn"],"referee":true,"identifiers":{"issn":["0913-3941"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:210, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250977","label":"url"}],"paper_title":{"en":"オクルーザルボンディング法に関する実験的研究 ポーセレンアンレーの厚みと支台歯形態が圧縮強度に及ぼす影響","ja":"オクルーザルボンディング法に関する実験的研究 ポーセレンアンレーの厚みと支台歯形態が圧縮強度に及ぼす影響"},"authors":{"en":[{"name":"Matsuka Yoshizo"},{"name":"矢谷 博文"},{"name":"近藤 康弘"},{"name":"窪木 拓男"},{"name":"天野 洋一"},{"name":"山下 敦"}],"ja":[{"name":"松香 芳三"},{"name":"矢谷 博文"},{"name":"近藤 康弘"},{"name":"窪木 拓男"},{"name":"天野 洋一"},{"name":"山下 敦"}]},"publication_date":"1991","publication_name":{"en":"The Journal of the Japan Association of Cranio-Mandibular Orthopedics","ja":"日本顎頭蓋機能学会誌"},"volume":"Vol.4","number":"No.1","starting_page":"15","ending_page":"23","languages":["jpn"],"referee":true,"identifiers":{"issn":["1340-8852"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:211, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250976","label":"url"}],"paper_title":{"en":"ヒト関節円板の形態学的特徴と関節円板転位の関連に関する肉眼解剖学的研究","ja":"ヒト関節円板の形態学的特徴と関節円板転位の関連に関する肉眼解剖学的研究"},"authors":{"en":[{"name":"天野 洋一"},{"name":"矢谷 博文"},{"name":"窪木 拓男"},{"name":"Matsuka Yoshizo"},{"name":"山下 敦"}],"ja":[{"name":"天野 洋一"},{"name":"矢谷 博文"},{"name":"窪木 拓男"},{"name":"松香 芳三"},{"name":"山下 敦"}]},"publication_date":"1991","publication_name":{"en":"Journal of the Japanese Society for the Temporomandibular Joint","ja":"日本顎関節学会雑誌"},"volume":"Vol.3","number":"No.1","starting_page":"23","ending_page":"34","languages":["jpn"],"referee":true,"identifiers":{"issn":["0915-3004"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:212, {"insert":{"user_id":"B000340651","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250975","label":"url"}],"paper_title":{"en":"各種頭蓋顎関節エックス線規格撮影装置により得られた顎関節像の比較","ja":"各種頭蓋顎関節エックス線規格撮影装置により得られた顎関節像の比較"},"authors":{"en":[{"name":"矢谷 博文"},{"name":"Matsuka Yoshizo"},{"name":"窪木 拓男"},{"name":"天野 洋一"},{"name":"山下 敦"}],"ja":[{"name":"矢谷 博文"},{"name":"松香 芳三"},{"name":"窪木 拓男"},{"name":"天野 洋一"},{"name":"山下 敦"}]},"publication_date":"1990","publication_name":{"en":"The Journal of the Japan Association of Cranio-Mandibular Orthopedics","ja":"日本顎頭蓋機能学会誌"},"volume":"Vol.3","number":"No.1","starting_page":"57","ending_page":"65","languages":["jpn"],"referee":true,"identifiers":{"issn":["1340-8852"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:213, {"insert":{"user_id":"B000340651","type":"published_papers","id":"14797172"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=250974","label":"url"}],"paper_title":{"en":"ヒト関節円板の肉眼解剖学的研究","ja":"ヒト関節円板の肉眼解剖学的研究"},"authors":{"en":[{"name":"天野 洋一"},{"name":"矢谷 博文"},{"name":"窪木 拓男"},{"name":"Matsuka Yoshizo"},{"name":"山下 敦"}],"ja":[{"name":"天野 洋一"},{"name":"矢谷 博文"},{"name":"窪木 拓男"},{"name":"松香 芳三"},{"name":"山下 敦"}]},"publication_date":"1989","publication_name":{"en":"The Journal of the Japan Association of Cranio-Mandibular 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