=== Generating (published_papers) ===
=== Generating (teaching_experience) ===
=== Generating (misc) ===
=== Generating (research_projects) ===
=== Generating (books_etc) ===
=== Generating (presentations) ===
==== begin registerFile(/WWW/pub2/data/ERD/person/248930/researchmap/published_papers.jsonl) ====
line:1, {"insert":{"user_id":"R000010822","type":"published_papers","id":"44542765"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/38263395","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=404786","label":"url"}],"paper_title":{"en":"A novel CT-based radiomics model for predicting response and prognosis of chemoradiotherapy in esophageal squamous cell carcinoma.","ja":"A novel CT-based radiomics model for predicting response and prognosis of chemoradiotherapy in esophageal squamous cell carcinoma."},"authors":{"en":[{"name":"Kasai Akinari"},{"name":"Miyoshi Jinsei"},{"name":"Sato Yasushi"},{"name":"Okamoto Koichi"},{"name":"Miyamoto Hiroshi"},{"name":"Kawanaka Takashi"},{"name":"Tonoiso Chisato"},{"name":"Harada Masafumi"},{"name":"Goto Masakazu"},{"name":"Yoshida Takahiro"},{"name":"Haga Akihiro"},{"name":"Takayama Tetsuji"}],"ja":[{"name":"笠井 昭成"},{"name":"三好 人正"},{"name":"佐藤 康史"},{"name":"岡本 耕一"},{"name":"宮本 弘志"},{"name":"川中 崇"},{"name":"外礒 千智"},{"name":"原田 雅史"},{"name":"後藤 正和"},{"name":"吉田 卓弘"},{"name":"芳賀 昭弘"},{"name":"高山 哲治"}]},"description":{"en":"No clinically relevant biomarker has been identified for predicting the response of esophageal squamous cell carcinoma (ESCC) to chemoradiotherapy (CRT). Herein, we established a CT-based radiomics model with artificial intelligence (AI) to predict the response and prognosis of CRT in ESCC. A total of 44 ESCC patients (stage I-IV) were enrolled in this study; training (n = 27) and validation (n = 17) cohorts. First, we extracted a total of 476 radiomics features from three-dimensional CT images of cancer lesions in training cohort, selected 110 features associated with the CRT response by ROC analysis (AUC ≥ 0.7) and identified 12 independent features, excluding correlated features by Pearson's correlation analysis (r ≥ 0.7). Based on the 12 features, we constructed 5 prediction models of different machine learning algorithms (Random Forest (RF), Ridge Regression, Naive Bayes, Support Vector Machine, and Artificial Neural Network models). Among those, the RF model showed the highest AUC in the training cohort (0.99 [95%CI 0.86-1.00]) as well as in the validation cohort (0.92 [95%CI 0.71-0.99]) to predict the CRT response. Additionally, Kaplan-Meyer analysis of the validation cohort and all the patient data showed significantly longer progression-free and overall survival in the high-prediction score group compared with the low-prediction score group in the RF model. Univariate and multivariate analyses revealed that the radiomics prediction score and lymph node metastasis were independent prognostic biomarkers for CRT of ESCC. In conclusion, we have developed a CT-based radiomics model using AI, which may have the potential to predict the CRT response as well as the prognosis for ESCC patients with non-invasiveness and cost-effectiveness.","ja":"No clinically relevant biomarker has been identified for predicting the response of esophageal squamous cell carcinoma (ESCC) to chemoradiotherapy (CRT). Herein, we established a CT-based radiomics model with artificial intelligence (AI) to predict the response and prognosis of CRT in ESCC. A total of 44 ESCC patients (stage I-IV) were enrolled in this study; training (n = 27) and validation (n = 17) cohorts. First, we extracted a total of 476 radiomics features from three-dimensional CT images of cancer lesions in training cohort, selected 110 features associated with the CRT response by ROC analysis (AUC ≥ 0.7) and identified 12 independent features, excluding correlated features by Pearson's correlation analysis (r ≥ 0.7). Based on the 12 features, we constructed 5 prediction models of different machine learning algorithms (Random Forest (RF), Ridge Regression, Naive Bayes, Support Vector Machine, and Artificial Neural Network models). Among those, the RF model showed the highest AUC in the training cohort (0.99 [95%CI 0.86-1.00]) as well as in the validation cohort (0.92 [95%CI 0.71-0.99]) to predict the CRT response. Additionally, Kaplan-Meyer analysis of the validation cohort and all the patient data showed significantly longer progression-free and overall survival in the high-prediction score group compared with the low-prediction score group in the RF model. Univariate and multivariate analyses revealed that the radiomics prediction score and lymph node metastasis were independent prognostic biomarkers for CRT of ESCC. In conclusion, we have developed a CT-based radiomics model using AI, which may have the potential to predict the CRT response as well as the prognosis for ESCC patients with non-invasiveness and cost-effectiveness."},"publication_date":"2024-01-23","publication_name":{"en":"Scientific Reports","ja":"Scientific Reports"},"volume":"Vol.14","number":"No.1","starting_page":"2039","ending_page":"2039","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1038/s41598-024-52418-4"],"issn":["2045-2322"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:2, {"insert":{"user_id":"R000010822","type":"published_papers","id":"44457491"},"force":{"see_also":[{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85153283320&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=404643","label":"url"}],"paper_title":{"en":"Therapeutic Strategy for Chylothorax After Esophagectomy: Lymphangiography with an Inguinal Intranodal Approach","ja":"Therapeutic Strategy for Chylothorax After Esophagectomy: Lymphangiography with an Inguinal Intranodal Approach"},"authors":{"en":[{"name":"Inoue Seiya"},{"name":"Goto Masakazu"},{"name":"Shono Takashi"},{"name":"Takasugi Haruka"},{"name":"Fujiwara Satoshi"},{"name":"Takizawa Hiromitsu"}],"ja":[{"name":"井上 聖也"},{"name":"後藤 正和"},{"name":"庄野 隆志"},{"name":"髙杉 遥"},{"name":"藤原 聡史"},{"name":"滝沢 宏光"}]},"publication_date":"2023-04","publication_name":{"en":"The Indian Journal of Surgery","ja":"The Indian Journal of Surgery"},"volume":"Vol.85","number":"No.6","starting_page":"1421","ending_page":"1426","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s12262-023-03773-5"],"issn":["0973-9793"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:3, {"insert":{"user_id":"R000010822","type":"published_papers","id":"41182793"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36523308","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=393678","label":"url"}],"paper_title":{"en":"Abscopal effect in a patient with solitary extramedullary plasmacytoma of the thyroid: case report","ja":"Abscopal effect in a patient with solitary extramedullary plasmacytoma of the thyroid: case report"},"authors":{"en":[{"name":"Aoyama Mariko"},{"name":"Shono Takashi"},{"name":"INUI Tomohiro"},{"name":"Miyamoto Naoki"},{"name":"Sakamoto Shin-ichi"},{"name":"Inoue Seiya"},{"name":"Fujiwara Satoshi"},{"name":"Goto Masakazu"},{"name":"Toba Hiroaki"},{"name":"Takizawa Hiromitsu"}],"ja":[{"name":"青山 万理子"},{"name":"庄野 隆志"},{"name":"乾 友浩"},{"name":"宮本 直輝"},{"name":"坂本 晋一"},{"name":"井上 聖也"},{"name":"藤原 聡史"},{"name":"後藤 正和"},{"name":"鳥羽 博明"},{"name":"滝沢 宏光"}]},"description":{"en":"The abscopal effect is a systemic antitumor response that occurs distant to the irradiation site and is induced by local irradiation. We herein describe a case of solitary extramedullary plasmacytoma (SEP) of the thyroid in which bone metastases disappeared after thyroidectomy and cervical radiotherapy (RT). A 68-year-old man with a right cervical swelling for approximately 10 years visited a hospital with left elbow pain that persisted for 5 months. He was referred to our hospital for more detailed examinations and treatment. An immobile mass of approximately 10 cm in diameter was palpable on the right side of the patient's neck. Computed tomography (CT) showed osteolytic changes in the left humerus and right scapula, and a tumor in the right lobe of the thyroid gland. The patient was diagnosed with widely invasive follicular carcinoma and multiple bone metastases and underwent total thyroidectomy. During surgery, tumor infiltration into the trachea was observed. Shaving between the tumor and trachea was performed. Based on the results of a pathological examination, the patient was diagnosed with primary extramedullary plasmacytoma of the thyroid. After surgery, external beam RT was performed on the neck, which also reduced the pain in the left elbow. Positron emission tomography (PET)-CT showed the decreased accumulation of fluorodeoxyglucose (FDG) in the left humerus and right scapula, and the amelioration of osteolytic changes on CT. SEP of the thyroid is rare, and to the best of our knowledge, this is the first case report in which the abscopal effect was observed after thyroidectomy and cervical RT.","ja":"The abscopal effect is a systemic antitumor response that occurs distant to the irradiation site and is induced by local irradiation. We herein describe a case of solitary extramedullary plasmacytoma (SEP) of the thyroid in which bone metastases disappeared after thyroidectomy and cervical radiotherapy (RT). A 68-year-old man with a right cervical swelling for approximately 10 years visited a hospital with left elbow pain that persisted for 5 months. He was referred to our hospital for more detailed examinations and treatment. An immobile mass of approximately 10 cm in diameter was palpable on the right side of the patient's neck. Computed tomography (CT) showed osteolytic changes in the left humerus and right scapula, and a tumor in the right lobe of the thyroid gland. The patient was diagnosed with widely invasive follicular carcinoma and multiple bone metastases and underwent total thyroidectomy. During surgery, tumor infiltration into the trachea was observed. Shaving between the tumor and trachea was performed. Based on the results of a pathological examination, the patient was diagnosed with primary extramedullary plasmacytoma of the thyroid. After surgery, external beam RT was performed on the neck, which also reduced the pain in the left elbow. Positron emission tomography (PET)-CT showed the decreased accumulation of fluorodeoxyglucose (FDG) in the left humerus and right scapula, and the amelioration of osteolytic changes on CT. SEP of the thyroid is rare, and to the best of our knowledge, this is the first case report in which the abscopal effect was observed after thyroidectomy and cervical RT."},"publication_date":"2022-11","publication_name":{"en":"Translational Cancer Research","ja":"Translational Cancer Research"},"volume":"Vol.11","number":"No.11","starting_page":"4200","ending_page":"4205","languages":["eng"],"referee":true,"identifiers":{"doi":["10.21037/tcr-22-1419"],"issn":["2219-6803"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:4, {"insert":{"user_id":"R000010822","type":"published_papers","id":"41182794"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/35975227","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=393677","label":"url"}],"paper_title":{"en":"A case of papillary thyroid carcinoma with renal and pulmonary metastases","ja":"A case of papillary thyroid carcinoma with renal and pulmonary metastases"},"authors":{"en":[{"name":"Aoyama Mariko"},{"name":"Inui Tomohiro"},{"name":"Miyamoto Naoki"},{"name":"Sakamoto Shin-ichi"},{"name":"Inoue Seiya"},{"name":"Fujiwara Satoshi"},{"name":"Goto Masakazu"},{"name":"Toba Hiroaki"},{"name":"Takizawa Hiromitsu"}],"ja":[{"name":"青山 万理子"},{"name":"乾 友浩"},{"name":"宮本 直輝"},{"name":"坂本 晋一"},{"name":"井上 聖也"},{"name":"藤原 聡史"},{"name":"後藤 正和"},{"name":"鳥羽 博明"},{"name":"滝沢 宏光"}]},"description":{"en":"Distant metastases derived from papillary carcinoma are generally detected in the lungs and bones. However, renal metastasis is rare. We herein report a case of papillary thyroid carcinoma with renal and pulmonary metastases that had been initially diagnosed as primary renal carcinoma with pulmonary metastases. The lesions showed response to immune checkpoint inhibitors and tyrosine kinase inhibitor but not to radioactive iodine therapy.","ja":"Distant metastases derived from papillary carcinoma are generally detected in the lungs and bones. However, renal metastasis is rare. We herein report a case of papillary thyroid carcinoma with renal and pulmonary metastases that had been initially diagnosed as primary renal carcinoma with pulmonary metastases. The lesions showed response to immune checkpoint inhibitors and tyrosine kinase inhibitor but not to radioactive iodine therapy."},"publication_date":"2022-08-13","publication_name":{"en":"Journal of Surgical Case Reports","ja":"Journal of Surgical Case Reports"},"volume":"Vol.2022","number":"No.8","starting_page":"rjac366","ending_page":"rjac366","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1093/jscr/rjac366"],"issn":["2042-8812"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:5, {"insert":{"user_id":"R000010822","type":"published_papers","id":"41182795"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/34969725","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=393671","label":"url"}],"paper_title":{"en":"ypN0 in Patients with Definitive cN-positive Status After Preoperative Treatment Is a Prognostic Factor in Esophageal Cancer","ja":"ypN0 in Patients with Definitive cN-positive Status After Preoperative Treatment Is a Prognostic Factor in Esophageal Cancer"},"authors":{"en":[{"name":"Yoshida Takahiro"},{"name":"Nishino Takeshi"},{"name":"Goto Masakazu"},{"name":"Inoue Seiya"},{"name":"Fujiwara Satoshi"},{"name":"Takizawa Hiromitsu"},{"name":"Tangoku Akira"},{"name":"Uehara Hisanori"},{"name":"Bando Yoshimi"}],"ja":[{"name":"吉田 卓弘"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"井上 聖也"},{"name":"藤原 聡史"},{"name":"滝沢 宏光"},{"name":"丹黒 章"},{"name":"上原 久典"},{"name":"坂東 良美"}]},"description":{"en":"Histopathological tumor regression grade is applied not to lymph nodes but primary tumors modified by preoperative treatments. This study focused on patients whose pathological examination at the time of surgery showed no residual tumor after chemo(radio)therapy in the primary lesion (ypT0) or lymph nodes (ypN0). A total of 87 patients with clinical stage II/III thoracic esophageal cancer underwent esophagectomy following preoperative treatments to evaluate significances between pathological response and clinical outcomes; 51 patients with clinically definitive lymph node metastasis (cN+) were analyzed as a subgroup. ypT0 rates were 20.7% and 23.5%, and ypN0 rates were 47.1% and 27.5% in the whole cohort and in the cN+ subgroup, respectively. Disease-free survival, from surgery to relapse or death, was significantly influenced by ypN status (p=0.035) but not by ypT status in the 51 patients with definitive cN+ disease. Preoperative chemoradiation was an independent favorable factor for achievement of ypN0 in the 51 patients (odds ratio=0.09; p=0.007). ypN status was a predictive factor for DFS in patients treated with docetaxel plus low-dose 5-fluorouracil and cisplatin combined chemotherapy, superior to ypT status, especially in patients with definitive cN+ disease.","ja":"Histopathological tumor regression grade is applied not to lymph nodes but primary tumors modified by preoperative treatments. This study focused on patients whose pathological examination at the time of surgery showed no residual tumor after chemo(radio)therapy in the primary lesion (ypT0) or lymph nodes (ypN0). A total of 87 patients with clinical stage II/III thoracic esophageal cancer underwent esophagectomy following preoperative treatments to evaluate significances between pathological response and clinical outcomes; 51 patients with clinically definitive lymph node metastasis (cN+) were analyzed as a subgroup. ypT0 rates were 20.7% and 23.5%, and ypN0 rates were 47.1% and 27.5% in the whole cohort and in the cN+ subgroup, respectively. Disease-free survival, from surgery to relapse or death, was significantly influenced by ypN status (p=0.035) but not by ypT status in the 51 patients with definitive cN+ disease. Preoperative chemoradiation was an independent favorable factor for achievement of ypN0 in the 51 patients (odds ratio=0.09; p=0.007). ypN status was a predictive factor for DFS in patients treated with docetaxel plus low-dose 5-fluorouracil and cisplatin combined chemotherapy, superior to ypT status, especially in patients with definitive cN+ disease."},"publication_date":"2022-01","publication_name":{"en":"Anticancer Research","ja":"Anticancer Research"},"volume":"Vol.42","number":"No.1","starting_page":"195","ending_page":"203","languages":["eng"],"referee":true,"identifiers":{"doi":["10.21873/anticanres.15473"],"issn":["1791-7530"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:6, {"insert":{"user_id":"R000010822","type":"published_papers","id":"41182792"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/118024","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85136678999&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=393679","label":"url"}],"paper_title":{"en":"Spontaneous esophageal perforation within a hiatal hernia: A case report","ja":"Spontaneous esophageal perforation within a hiatal hernia: A case report"},"authors":{"en":[{"name":"Maki Hidenori"},{"name":"Inoue Seiya"},{"name":"Goto Masakazu"},{"name":"Nishino Takeshi"},{"name":"Yoshida Takahiro"},{"name":"Takizawa Hiromitsu"}],"ja":[{"name":"牧 秀則"},{"name":"井上 聖也"},{"name":"後藤 正和"},{"name":"西野 豪志"},{"name":"吉田 卓弘"},{"name":"滝沢 宏光"}]},"publication_date":"2022","publication_name":{"en":"International Journal of Surgery Case Reports","ja":"International Journal of Surgery Case Reports"},"volume":"Vol.98","starting_page":"107484","ending_page":"107484","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.ijscr.2022.107484"],"issn":["2210-2612"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:7, {"insert":{"user_id":"R000010822","type":"published_papers","id":"41540021"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/34383155","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=394087","label":"url"}],"paper_title":{"en":"Impact of preoperative 6-minute walk distance on long-term prognosis after esophagectomy in patients with esophageal cancer.","ja":"Impact of preoperative 6-minute walk distance on long-term prognosis after esophagectomy in patients with esophageal cancer."},"authors":{"en":[{"name":"Kondo Shin"},{"name":"Inoue Tatsuro"},{"name":"Yoshida Takahiro"},{"name":"Saito Takashi"},{"name":"Inoue Seiya"},{"name":"Nishino Takeshi"},{"name":"Goto Masakazu"},{"name":"Sato Nori"},{"name":"Ono Rei"},{"name":"Tangoku Akira"},{"name":"Katoh Shinsuke"}],"ja":[{"name":"Kondo Shin"},{"name":"Inoue Tatsuro"},{"name":"吉田 卓弘"},{"name":"Saito Takashi"},{"name":"井上 聖也"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"佐藤 紀"},{"name":"Ono Rei"},{"name":"丹黒 章"},{"name":"加藤 真介"}]},"description":{"en":"The preoperative 6MWD is useful for evaluating exercise capacity and predicting the long-term outcome in patients undergoing esophagectomy.","ja":"The median follow-up period was 923 days. Thirty-three deaths were recorded during the study period. After PSM, 5-year OS following surgery was 29.2 and 66.1% (p = 0.003) and 5-year RFS was 27.9 and 58.6% (p = 0.021) in the SG and LG, respectively. In Cox proportional hazards analysis, the SG was a significant independent risk factor for OS (hazard ratio 3.33; 95% confidence interval 1.37-8.11, p = 0.008) and RFS (hazard ratio 2.30; 95% confidence interval 1.08-4.88, p = 0.030)."},"publication_date":"2021-08-12","publication_name":{"en":"Esophagus","ja":"Esophagus"},"volume":"Vol.19","number":"No.1","starting_page":"95","ending_page":"104","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s10388-021-00871-9"],"issn":["1612-9067"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:8, {"insert":{"user_id":"R000010822","type":"published_papers","id":"36212745"},"force":{"see_also":[{"@id":"http://id.ndl.go.jp/bib/031576334","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390569932783885568/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=383761","label":"url"}],"paper_title":{"en":"食道癌手術における高度胸膜癒着症例への対処","ja":"食道癌手術における高度胸膜癒着症例への対処"},"authors":{"en":[{"name":"Tangoku Akira"},{"name":"Takizawa Hiromitsu"},{"name":"Yoshida Takahiro"},{"name":"Goto Masakazu"},{"name":"Inoue Seiya"},{"name":"都築 英雄"}],"ja":[{"name":"丹黒 章"},{"name":"滝沢 宏光"},{"name":"吉田 卓弘"},{"name":"後藤 正和"},{"name":"井上 聖也"},{"name":"都築 英雄"}]},"publication_date":"2021-06-15","publication_name":{"en":"Operation","ja":"手術"},"volume":"Vol.75","number":"No.7","starting_page":"1069","ending_page":"1074","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.18888/op.0000002281"],"issn":["0037-4423"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:9, {"insert":{"user_id":"R000010822","type":"published_papers","id":"33229619"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/33826003","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85103949292&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=383774","label":"url"}],"paper_title":{"en":"Endobronchial Ultrasound Improves the Diagnosis of the Tracheobronchial Invasion of Advanced Esophageal Cancer","ja":"Endobronchial Ultrasound Improves the Diagnosis of the Tracheobronchial Invasion of Advanced Esophageal Cancer"},"authors":{"en":[{"name":"Nishino Takeshi"},{"name":"Toba Hiroaki"},{"name":"Yoshida Takahiro"},{"name":"Inoue Seiya"},{"name":"Goto Masakazu"},{"name":"Kawakita Naoya"},{"name":"Takizawa Hiromitsu"},{"name":"Tsuruo Yoshihiro"},{"name":"Tangoku Akira"}],"ja":[{"name":"西野 豪志"},{"name":"鳥羽 博明"},{"name":"吉田 卓弘"},{"name":"井上 聖也"},{"name":"後藤 正和"},{"name":"河北 直也"},{"name":"滝沢 宏光"},{"name":"鶴尾 吉宏"},{"name":"丹黒 章"}]},"description":{"en":"Accurate diagnosis of the tracheobronchial invasion of advanced esophageal cancer is essential to select appropriate treatment and improve prognosis; however, it is difficult using the conventional modalities. This study aimed to clarify the diagnostic usefulness of convex probe endobronchial ultrasound (CP-EBUS) for the diagnosis of the tracheobronchial invasion of advanced esophageal cancer. We conducted a cadaveric study to clarify the changes in ultrasonic and histopathologic findings in the esophageal tumor and tracheal invasion models. Additionally, we examined CP-EBUS for patients with advanced thoracic esophageal cancer in whom tracheobronchial invasion was suspected on contrast-enhanced computed tomography (CE-CT) scan. We retrospectivity evaluated the diagnosis of CP-EBUS, comparing the pathological findings and treatment outcomes. Cadaveric esophageal tumor and tracheal invasion models showed the disappearance of the third layer observed with CP-EBUS and histologically proven interruption of the adventitia. This indicated that the third layer corresponded with the tracheal adventitia. We examined 40 patients with advanced thoracic esophageal cancer in whom tracheobronchial invasion was suspected. The precise diagnosis was pathologically confirmed in 9 of 14 patients diagnosed with cT3 who underwent radical surgery. 20 of 26 cases diagnosed with cT4b received definitive chemoradiotherapy, and 4 cases received salvage surgery and pathologically confirmed precise diagnosis. CP-EBUS is extremely useful for diagnosing the tracheobronchial invasion of advanced esophageal cancer. It could be an effective modality for determining treatment strategies in cases with a marginal surgical indication.","ja":"Accurate diagnosis of the tracheobronchial invasion of advanced esophageal cancer is essential to select appropriate treatment and improve prognosis; however, it is difficult using the conventional modalities. This study aimed to clarify the diagnostic usefulness of convex probe endobronchial ultrasound (CP-EBUS) for the diagnosis of the tracheobronchial invasion of advanced esophageal cancer. We conducted a cadaveric study to clarify the changes in ultrasonic and histopathologic findings in the esophageal tumor and tracheal invasion models. Additionally, we examined CP-EBUS for patients with advanced thoracic esophageal cancer in whom tracheobronchial invasion was suspected on contrast-enhanced computed tomography (CE-CT) scan. We retrospectivity evaluated the diagnosis of CP-EBUS, comparing the pathological findings and treatment outcomes. Cadaveric esophageal tumor and tracheal invasion models showed the disappearance of the third layer observed with CP-EBUS and histologically proven interruption of the adventitia. This indicated that the third layer corresponded with the tracheal adventitia. We examined 40 patients with advanced thoracic esophageal cancer in whom tracheobronchial invasion was suspected. The precise diagnosis was pathologically confirmed in 9 of 14 patients diagnosed with cT3 who underwent radical surgery. 20 of 26 cases diagnosed with cT4b received definitive chemoradiotherapy, and 4 cases received salvage surgery and pathologically confirmed precise diagnosis. CP-EBUS is extremely useful for diagnosing the tracheobronchial invasion of advanced esophageal cancer. It could be an effective modality for determining treatment strategies in cases with a marginal surgical indication."},"publication_date":"2021-04-07","publication_name":{"en":"Annals of Surgical Oncology","ja":"Annals of Surgical Oncology"},"volume":"Vol.28","number":"No.11","starting_page":"6398","ending_page":"6406","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1245/s10434-021-09912-0"],"issn":["1534-4681"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:10, {"insert":{"user_id":"R000010822","type":"published_papers","id":"36212744"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/33811307","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85103853903&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=377725","label":"url"}],"paper_title":{"en":"ASO Author Reflections: CXCR7 and CXCL12 Expression as Biomarker in Patients with Esophageal Adenocarcinoma.","ja":"ASO Author Reflections: CXCR7 and CXCL12 Expression as Biomarker in Patients with Esophageal Adenocarcinoma."},"authors":{"en":[{"name":"Goto Masakazu"},{"name":"Liu Mingyao"}],"ja":[{"name":"後藤 正和"},{"name":"Liu Mingyao"}]},"publication_date":"2021-04-02","publication_name":{"en":"Annals of Surgical Oncology","ja":"Annals of Surgical Oncology"},"volume":"Vol.28","number":"No.9","starting_page":"4952","ending_page":"4952","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1245/s10434-021-09807-0"],"issn":["1534-4681"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:11, {"insert":{"user_id":"R000010822","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/33709176","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=377726","label":"url"}],"paper_title":{"en":"Prognostic Impact of CXCR7 and CXCL12 Expression in Patients with Esophageal Adenocarcinoma.","ja":"Prognostic Impact of CXCR7 and CXCL12 Expression in Patients with Esophageal Adenocarcinoma."},"authors":{"en":[{"name":"Goto Masakazu"},{"name":"Shibahara Yukiko"},{"name":"Baciu Cristina"},{"name":"Allison Frances"},{"name":"Yeung Jonathan C"},{"name":"Darling Gail E"},{"name":"Liu Mingyao"}],"ja":[{"name":"後藤 正和"},{"name":"Shibahara Yukiko"},{"name":"Baciu Cristina"},{"name":"Allison Frances"},{"name":"Yeung Jonathan C"},{"name":"Darling Gail E"},{"name":"Liu Mingyao"}]},"description":{"en":"High CXCR7 expression was associated with poor prognosis in patients with EAC, and high expression of CXCR7 with its ligand CXCL12 had a stronger association with prognosis. Further study of this potential biomarker using whole tissue samples and a larger sample size is warranted.","ja":"High CXCR7 expression was significantly associated with lymphatic invasion (present vs absent, P = 0.005) and higher number of lymph node metastases (pN0-1 vs pN2-3, P = 0.0014). Patients with high CXCR7 expression (n = 23) were associated with worse overall (OS) and disease-free survival (DFS) (P = 0.0221, P = 0.0090, respectively), and patients with high CXCL12 (n = 24) tended to have worse OS and DFS (P = 0.1091, P = 0.1477, respectively). High expression of both CXCR7 and CXCL12 was an independent prognostic factor for OS and DFS on multivariate analysis (HR = 0.3, 95% CI: 0.1-0.9, P = 0.0246, HR = 0.3, 95% CI: 0.1-0.8, P = 0.0134, respectively)."},"publication_date":"2021-03-11","publication_name":{"en":"Annals of Surgical Oncology","ja":"Annals of Surgical Oncology"},"volume":"Vol.28","number":"No.9","starting_page":"4943","ending_page":"4951","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1245/s10434-021-09775-5"],"issn":["1534-4681"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:12, {"insert":{"user_id":"R000010822","type":"published_papers","id":"33229621"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/115936","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/33449265","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85099215910&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=377727","label":"url"}],"paper_title":{"en":"Biomarkers predicting the response to chemotherapy and the prognosis in patients with esophageal squamous cell carcinoma.","ja":"Biomarkers predicting the response to chemotherapy and the prognosis in patients with esophageal squamous cell carcinoma."},"authors":{"en":[{"name":"Inoue Seiya"},{"name":"Yoshida Takahiro"},{"name":"Nishino Takeshi"},{"name":"Goto Masakazu"},{"name":"Aoyama Mariko"},{"name":"Kawakita Naoya"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Takizawa Hiromitsu"},{"name":"Tangoku Akira"}],"ja":[{"name":"井上 聖也"},{"name":"吉田 卓弘"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"青山 万理子"},{"name":"河北 直也"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"滝沢 宏光"},{"name":"丹黒 章"}]},"description":{"en":"The prognosis of patients with esophageal squamous cell carcinoma (ESCC) has been improved by multidisciplinary therapy with chemoradiotherapy and surgery, but it remains poor. Advanced stage, malignant potential, and chemo-resistance contribute to the poor prognosis. Here, we attempted to identify predictive factors of the response to chemotherapy and the prognosis of ESCC patients. We examined 51 ESCC patients who were treated with chemotherapy followed by radical surgery, and 23 patients who were treated with chemotherapy alone. We conducted quantitative reverse transcription-polymerase chain reaction gene expression analysis using RNA extracted from 74 tumor tissue samples collected before chemotherapy and 67 tumor tissue samples collected after chemotherapy, focusing on PIK3CA, AKT-1, mTOR, 4E-BP1, p70S6K, PD-L1, and PD-L2. The proportions of patients with high expressions of AKT-1 and PD-L1 before chemotherapy were significantly higher among the non-responders than among the responders (p = 0.034, p = 0.020, respectively). Multivariate analyses revealed that high PD-L1 expression before chemotherapy was associated with poor response to chemotherapy (odds ratio 2.998; 95% CI 1.043-8.619; p = 0.042) and high p70S6K expression before chemotherapy was a poor prognostic factor (hazard ratio 2.518; 95% CI 1.058-5.988; p = 0.037). In addition, the patients with high expression of PD-L1 and PD-L2 in the tumors after chemotherapy had significantly worse survival than those with low expression of these genes (p = 0.012, p = 0.007, respectively). These results demonstrated that PD-L1 and p70S6K in the primary ESCC tissues were related to a poor response to chemotherapy and poor prognosis, respectively.","ja":"The prognosis of patients with esophageal squamous cell carcinoma (ESCC) has been improved by multidisciplinary therapy with chemoradiotherapy and surgery, but it remains poor. Advanced stage, malignant potential, and chemo-resistance contribute to the poor prognosis. Here, we attempted to identify predictive factors of the response to chemotherapy and the prognosis of ESCC patients. We examined 51 ESCC patients who were treated with chemotherapy followed by radical surgery, and 23 patients who were treated with chemotherapy alone. We conducted quantitative reverse transcription-polymerase chain reaction gene expression analysis using RNA extracted from 74 tumor tissue samples collected before chemotherapy and 67 tumor tissue samples collected after chemotherapy, focusing on PIK3CA, AKT-1, mTOR, 4E-BP1, p70S6K, PD-L1, and PD-L2. The proportions of patients with high expressions of AKT-1 and PD-L1 before chemotherapy were significantly higher among the non-responders than among the responders (p = 0.034, p = 0.020, respectively). Multivariate analyses revealed that high PD-L1 expression before chemotherapy was associated with poor response to chemotherapy (odds ratio 2.998; 95% CI 1.043-8.619; p = 0.042) and high p70S6K expression before chemotherapy was a poor prognostic factor (hazard ratio 2.518; 95% CI 1.058-5.988; p = 0.037). In addition, the patients with high expression of PD-L1 and PD-L2 in the tumors after chemotherapy had significantly worse survival than those with low expression of these genes (p = 0.012, p = 0.007, respectively). These results demonstrated that PD-L1 and p70S6K in the primary ESCC tissues were related to a poor response to chemotherapy and poor prognosis, respectively."},"publication_date":"2021-01-15","publication_name":{"en":"General Thoracic and Cardiovascular Surgery","ja":"General Thoracic and Cardiovascular Surgery"},"volume":"Vol.69","number":"No.3","starting_page":"525","ending_page":"533","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s11748-021-01586-5"],"issn":["1863-6713"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:13, {"insert":{"user_id":"R000010822","type":"published_papers","id":"33229622"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116023","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/33994473","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=377722","label":"url"}],"paper_title":{"en":"A CASE OF VAGUS NERVE SCHWANNOMA DIFFICULT TO DISTINGUISH FROM LYMPH NODAL METASTASIS OF ESOPHAGEAL CANCER.","ja":"A CASE OF VAGUS NERVE SCHWANNOMA DIFFICULT TO DISTINGUISH FROM LYMPH NODAL METASTASIS OF ESOPHAGEAL CANCER."},"authors":{"en":[{"name":"Miyamoto Naoki"},{"name":"Inoue Seiya"},{"name":"Nishino Takeshi"},{"name":"Goto Masakazu"},{"name":"Yoshida Takahiro"},{"name":"Kobayashi Tomoko"},{"name":"Bando Yoshimi"},{"name":"Takizawa Hiromitsu"},{"name":"Tangoku Akira"}],"ja":[{"name":"宮本 直輝"},{"name":"井上 聖也"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"吉田 卓弘"},{"name":"小林 智子"},{"name":"坂東 良美"},{"name":"滝沢 宏光"},{"name":"丹黒 章"}]},"description":{"en":"In this report, we describe a rare case of vagus nerve schwannoma associated with esophageal cancer. A 70-year-old man visited our hospital complaining of worsening dysphagia. His upper gastrointenstinal endoscopy revealed a mass in the esophagus. A contrast-enhanced chest computed tomography also detected a 15 mm nodule attached to the tracheal membrane. This nodule was diagnosed as a metastatic lymph node. Although the primary tumor reduced after neoadjuvant chemotherapy, the nodule remained intact ; it showed fluorodeoxyglucose accumulation on positron emission tomography. We had a clinical diagnosis of stage III after neoadjuvant chemotherapy and underwent surgery. Intraoperatively, the nodule could not be detached from the right vagus nerve ; therefore, we excised the nodule along with the adjacent vagus nerve. The nodule was pathologically diagnosed as a vagus schwannoma. The nodule was not a regional lymph node metastasis of esophageal cancer. His postoperative course was uneventful, and he is currently undergoing outpatient follow-up without recurrence. J. Med. Invest. 68 : 205-208, February, 2021.","ja":"In this report, we describe a rare case of vagus nerve schwannoma associated with esophageal cancer. A 70-year-old man visited our hospital complaining of worsening dysphagia. His upper gastrointenstinal endoscopy revealed a mass in the esophagus. A contrast-enhanced chest computed tomography also detected a 15 mm nodule attached to the tracheal membrane. This nodule was diagnosed as a metastatic lymph node. Although the primary tumor reduced after neoadjuvant chemotherapy, the nodule remained intact ; it showed fluorodeoxyglucose accumulation on positron emission tomography. We had a clinical diagnosis of stage III after neoadjuvant chemotherapy and underwent surgery. Intraoperatively, the nodule could not be detached from the right vagus nerve ; therefore, we excised the nodule along with the adjacent vagus nerve. The nodule was pathologically diagnosed as a vagus schwannoma. The nodule was not a regional lymph node metastasis of esophageal cancer. His postoperative course was uneventful, and he is currently undergoing outpatient follow-up without recurrence. J. Med. Invest. 68 : 205-208, February, 2021."},"publication_date":"2021","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.68","number":"No.1.2","starting_page":"205","ending_page":"208","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.68.205"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:14, {"insert":{"user_id":"R000010822","type":"published_papers","id":"31403683"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/31776810","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85075623295&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=373118","label":"url"}],"paper_title":{"en":"The sterno-tracheal distance is an important factor of anastomotic leakage of retrosternal gastric tube reconstruction after esophagectomy","ja":"The sterno-tracheal distance is an important factor of anastomotic leakage of retrosternal gastric tube reconstruction after esophagectomy"},"authors":{"en":[{"name":"Inoue Seiya"},{"name":"Yoshida Takahiro"},{"name":"Nishino Takeshi"},{"name":"Goto Masakazu"},{"name":"Furukita Yoshihito"},{"name":"Yamamoto Yota"},{"name":"Fujiwara Satoshi"},{"name":"Minato Takuya"},{"name":"Sumitomo Hiroyuki"},{"name":"Yuasa Yasuhiro"},{"name":"Takizawa Hiromitsu"},{"name":"Tangoku Akira"}],"ja":[{"name":"井上 聖也"},{"name":"吉田 卓弘"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"古北 由仁"},{"name":"山本 洋太"},{"name":"藤原 聡史"},{"name":"湊 拓也"},{"name":"住友 弘幸"},{"name":"湯浅 康弘"},{"name":"滝沢 宏光"},{"name":"丹黒 章"}]},"description":{"en":"Anastomotic leakage (AL) is a serious complication after esophagectomy. The retrosternal (RS) route has been selected majorly to reduce reflux and related pneumonia and considering mediastinal recurrences. AL has been developed more in RS than posterior mediastinal (PM) route reconstruction. Therefore, we suspected the sterno-tracheal distance (STD) might be related to AL and started the selection according to the STD from 2009. A total of 221 patients who underwent a subtotal esophagectomy with gastric tube reconstruction during January 2004-April 2017 were investigated. The patients were classified into the 'after STD selection' (A; n = 144) group and the 'before STD selection' (B, n = 77) group. The incidences of and the risk factors for AL between the two groups were compared. The incidence of AL was high in the B group (18.2%), and 78.6% of the patients who developed AL were treated with RS route reconstruction. The median STDs of the patients with AL and no AL were 10.3 mm and 14.5 mm, respectively (p = 0.001). These results demonstrated that the STD was a risk factor for AL in the RS route. Based on these results, 13 mm was set as the cutoff value. After STD selection, the median STD increased from 14.0 to 17.3 mm (p = 0.001), and the incidence of AL decreased significantly from 26.2 to 11.1% in the RS route (p = 0.037). The STD was the independent risk factor for AL in the RS route. RS route reconstruction should be avoided for the patients with STD < 13 mm.","ja":"Anastomotic leakage (AL) is a serious complication after esophagectomy. The retrosternal (RS) route has been selected majorly to reduce reflux and related pneumonia and considering mediastinal recurrences. AL has been developed more in RS than posterior mediastinal (PM) route reconstruction. Therefore, we suspected the sterno-tracheal distance (STD) might be related to AL and started the selection according to the STD from 2009. A total of 221 patients who underwent a subtotal esophagectomy with gastric tube reconstruction during January 2004-April 2017 were investigated. The patients were classified into the 'after STD selection' (A; n = 144) group and the 'before STD selection' (B, n = 77) group. The incidences of and the risk factors for AL between the two groups were compared. The incidence of AL was high in the B group (18.2%), and 78.6% of the patients who developed AL were treated with RS route reconstruction. The median STDs of the patients with AL and no AL were 10.3 mm and 14.5 mm, respectively (p = 0.001). These results demonstrated that the STD was a risk factor for AL in the RS route. Based on these results, 13 mm was set as the cutoff value. After STD selection, the median STD increased from 14.0 to 17.3 mm (p = 0.001), and the incidence of AL decreased significantly from 26.2 to 11.1% in the RS route (p = 0.037). The STD was the independent risk factor for AL in the RS route. RS route reconstruction should be avoided for the patients with STD < 13 mm."},"publication_date":"2020-07","publication_name":{"en":"Esophagus","ja":"Esophagus"},"volume":"Vol.17","number":"No.3","starting_page":"264","ending_page":"269","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s10388-019-00705-9"],"issn":["1612-9067"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:15, {"insert":{"user_id":"R000010822","type":"published_papers","id":"31403685"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/115428","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/33148905","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85095590219&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=373110","label":"url"}],"paper_title":{"en":"Safe central venous catheters for esophageal cancer treatment","ja":"Safe central venous catheters for esophageal cancer treatment"},"authors":{"en":[{"name":"Inoue Seiya"},{"name":"Yoshida Takahiro"},{"name":"Nishino Takeshi"},{"name":"Goto Masakazu"},{"name":"Nishioka Kouhei"},{"name":"Fujimoto Keisuke"},{"name":"Aoyama Mariko"},{"name":"Matsumoto Daisuke"},{"name":"Takizawa Hiromitsu"},{"name":"Tangoku Akira"}],"ja":[{"name":"井上 聖也"},{"name":"吉田 卓弘"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"西岡 康平"},{"name":"藤本 啓介"},{"name":"青山 万理子"},{"name":"松本 大資"},{"name":"滝沢 宏光"},{"name":"丹黒 章"}]},"description":{"en":"Introduction : Central venous catheter (CVC) use is essential for treating esophageal cancer. Peripherally inserted central catheters (PICC) are commonly used recently for improved patient comfort and safety. We compared centrally inserted central catheters (CICC) and PICC insertions and examined their safety. Methods : We retrospectively investigated complications at the catheter insertion and post-insertion for 199 patients' esophageal cancer treatment (CICC : 45, PICC : 154) from 2013 to 2018. In addition, we summarized the results of catheter tip culture. Results : No serious complications occurred at the catheter insertion in either group. The rate of complications at catheter insertion was 5.8% for PICC and 6.7% for CICC patients. Post-insertion complications were observed in 6.5% and 11.1% of patients with PICC and CICC, respectively, and this difference was not significant. The incidence of catheter-related blood stream infection (CRBSI) was significantly lower in PICC than CICC patients (0.3 vs. 1.8 / 1,000 catheter-days ; p = 0.029). Catheter-related thrombosis was observed in PICC : 0.5 and CICC : 0.6, and occlusion due to blood flow reversal was observed in PICC : 0.5 and CICC : 0.6. Conclusion : PICCs are safer and more effective than CICCs for the treatment of esophageal cancer, and reduce the incidence of CRBSI. We hope to standardize the insertion procedures, conventionalize techniques, and establish training systems. J. Med. Invest. 67 : 298-303, August, 2020.","ja":"Introduction : Central venous catheter (CVC) use is essential for treating esophageal cancer. Peripherally inserted central catheters (PICC) are commonly used recently for improved patient comfort and safety. We compared centrally inserted central catheters (CICC) and PICC insertions and examined their safety. Methods : We retrospectively investigated complications at the catheter insertion and post-insertion for 199 patients' esophageal cancer treatment (CICC : 45, PICC : 154) from 2013 to 2018. In addition, we summarized the results of catheter tip culture. Results : No serious complications occurred at the catheter insertion in either group. The rate of complications at catheter insertion was 5.8% for PICC and 6.7% for CICC patients. Post-insertion complications were observed in 6.5% and 11.1% of patients with PICC and CICC, respectively, and this difference was not significant. The incidence of catheter-related blood stream infection (CRBSI) was significantly lower in PICC than CICC patients (0.3 vs. 1.8 / 1,000 catheter-days ; p = 0.029). Catheter-related thrombosis was observed in PICC : 0.5 and CICC : 0.6, and occlusion due to blood flow reversal was observed in PICC : 0.5 and CICC : 0.6. Conclusion : PICCs are safer and more effective than CICCs for the treatment of esophageal cancer, and reduce the incidence of CRBSI. We hope to standardize the insertion procedures, conventionalize techniques, and establish training systems. J. Med. Invest. 67 : 298-303, August, 2020."},"publication_date":"2020","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.67","number":"No.3,4","starting_page":"298","ending_page":"303","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.67.298"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:16, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401413"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/31773415","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85075618546&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=362740","label":"url"}],"paper_title":{"en":"Chemokines and their receptors as biomarkers in esophageal cancer","ja":"Chemokines and their receptors as biomarkers in esophageal cancer"},"authors":{"en":[{"name":"Goto Masakazu"},{"name":"Mingyao Liu"}],"ja":[{"name":"後藤 正和"},{"name":"Mingyao Liu"}]},"description":{"en":"Esophageal cancer (EC) is one of the most lethal malignancies of the digestive tract and remains to be improved poor prognosis. Two histological subtypes, esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC), are major characteristics of EC. Deep understanding about both subtypes is essential to overcome EC. Here, we focus on chemokines and their receptors as biomarkers and their current applications for the prognosis in EC. We reviewed relevant articles identified using PubMed database for the chemokines and their receptors in EC analyzed by immunohistochemistry. The primary objective is to summarize evidences for them as prognostic biomarkers in EC. A total of twenty-one articles were reviewed after exclusion. Most studies have been done in ESCC, and less in EAC. CXCL12 and its receptor CXCR4 have been shown in both subtypes as biomarkers. CXCR7, CXCL8 and its receptor CXCR2, and CCL21 and its receptor CCR7 have been examined in ESCC. Although it was a small number of reports, CXCL10, CCL4, and CCL5 have been indicated to have anti-tumor effects in ESCC. Chemokines and their receptors have the potential to be the biomarkers in EC. Comparative studies between ESCC and EAC will reveal the similarity and difference in these two subtypes of EC. These studies may indicate whether these molecules play important roles in both subtypes or are unique to one or another.","ja":"Esophageal cancer (EC) is one of the most lethal malignancies of the digestive tract and remains to be improved poor prognosis. Two histological subtypes, esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EAC), are major characteristics of EC. Deep understanding about both subtypes is essential to overcome EC. Here, we focus on chemokines and their receptors as biomarkers and their current applications for the prognosis in EC. We reviewed relevant articles identified using PubMed database for the chemokines and their receptors in EC analyzed by immunohistochemistry. The primary objective is to summarize evidences for them as prognostic biomarkers in EC. A total of twenty-one articles were reviewed after exclusion. Most studies have been done in ESCC, and less in EAC. CXCL12 and its receptor CXCR4 have been shown in both subtypes as biomarkers. CXCR7, CXCL8 and its receptor CXCR2, and CCL21 and its receptor CCR7 have been examined in ESCC. Although it was a small number of reports, CXCL10, CCL4, and CCL5 have been indicated to have anti-tumor effects in ESCC. Chemokines and their receptors have the potential to be the biomarkers in EC. Comparative studies between ESCC and EAC will reveal the similarity and difference in these two subtypes of EC. These studies may indicate whether these molecules play important roles in both subtypes or are unique to one or another."},"publication_date":"2019-11-26","publication_name":{"en":"Esophagus","ja":"Esophagus"},"volume":"Vol.17","number":"No.2","starting_page":"113","ending_page":"121","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s10388-019-00706-8"],"issn":["1612-9067"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:17, {"insert":{"user_id":"R000010822","type":"published_papers","id":"33229623"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/31177169","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=377728","label":"url"}],"paper_title":{"en":"Thoracoscopic Oesophagectomy Using Prone Positioning for Oesophageal Cancer With Right Aortic Arch: A Case Report.","ja":"Thoracoscopic Oesophagectomy Using Prone Positioning for Oesophageal Cancer With Right Aortic Arch: A Case Report."},"authors":{"en":[{"name":"Goto Masakazu"},{"name":"Okitsu Hiroshi"},{"name":"Yuasa Yasuhiro"},{"name":"Kuramoto Shunsuke"},{"name":"Tomibayashi Atsushi"},{"name":"Matsumoto Daisuke"},{"name":"Mori Osamu"},{"name":"Tani Ryotaro"},{"name":"Edagawa Hiroshi"},{"name":"Matsuo Yuta"}],"ja":[{"name":"後藤 正和"},{"name":"沖津 宏"},{"name":"Yuasa Yasuhiro"},{"name":"Kuramoto Shunsuke"},{"name":"Tomibayashi Atsushi"},{"name":"松本 大資"},{"name":"Mori Osamu"},{"name":"Tani Ryotaro"},{"name":"Edagawa Hiroshi"},{"name":"Matsuo Yuta"}]},"description":{"en":"There exist only a few reports of thoracoscopic oesophagectomy for EC with RAA. Sufficient preoperative preparation and sharing an adequate strategy for the surgical approach with the surgical team are definitely necessary. Although the thoracoscopic approach for EC with RAA is useful, more considerations are needed for some issues.","ja":"There exist only a few reports of thoracoscopic oesophagectomy for EC with RAA. Sufficient preoperative preparation and sharing an adequate strategy for the surgical approach with the surgical team are definitely necessary. Although the thoracoscopic approach for EC with RAA is useful, more considerations are needed for some issues."},"publication_date":"2019-06","publication_name":{"en":"Anticancer Research","ja":"Anticancer Research"},"volume":"Vol.39","number":"No.6","starting_page":"3207","ending_page":"3211","languages":["eng"],"referee":true,"identifiers":{"doi":["10.21873/anticanres.13460"],"issn":["1791-7530"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:18, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401414"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/113422","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/31064939","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=361010","label":"url"}],"paper_title":{"en":"Acase of advanced colon cancer arising from a colonic graft foran esophago-bronchial fistula : A case report.","ja":"Acase of advanced colon cancer arising from a colonic graft foran esophago-bronchial fistula : A case report."},"authors":{"en":[{"name":"Takasugi Haruka"},{"name":"Yoshida Takahiro"},{"name":"Nishino Takeshi"},{"name":"Goto Masakazu"},{"name":"Inoue Seiya"},{"name":"Matsumoto Daisuke"},{"name":"Inui Tomohiro"},{"name":"Takizawa Hiromitsu"},{"name":"Tsuzuki Hideo"},{"name":"Taniki Toshikatsu"},{"name":"Tangoku Akira"}],"ja":[{"name":"Takasugi Haruka"},{"name":"吉田 卓弘"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"井上 聖也"},{"name":"Matsumoto Daisuke"},{"name":"Inui Tomohiro"},{"name":"滝沢 宏光"},{"name":"Tsuzuki Hideo"},{"name":"Taniki Toshikatsu"},{"name":"丹黒 章"}]},"description":{"en":"Neoplasm of a colonic graft after esophageal reconstruction is rare. We treated a colon cancer patient who developed malignancy in a colonic graft after esophagectomy and reconstruction through a retrosternal route. A male had undergone esophagectomy in his 50s due to a benign esophago-bronchial fistula. His dysphagia became exacerbated 20 years later, and further examinations showed a circumferential tumor on the esophagocolonic anastomosis. He underwent resection of the colonic graft adenocarcinoma with median sternotomy after neoadjuvant chemotherapy. Gastric tube reconstruction was performed through a retrosternal route. This report should be informative in terms of making decisions from an initial reconstruction to follow-up and choosing a therapeutic strategy for colonic graft cancer in the future. J. Med. Invest. 66 : 190-193, February, 2019.","ja":"Neoplasm of a colonic graft after esophageal reconstruction is rare. We treated a colon cancer patient who developed malignancy in a colonic graft after esophagectomy and reconstruction through a retrosternal route. A male had undergone esophagectomy in his 50s due to a benign esophago-bronchial fistula. His dysphagia became exacerbated 20 years later, and further examinations showed a circumferential tumor on the esophagocolonic anastomosis. He underwent resection of the colonic graft adenocarcinoma with median sternotomy after neoadjuvant chemotherapy. Gastric tube reconstruction was performed through a retrosternal route. This report should be informative in terms of making decisions from an initial reconstruction to follow-up and choosing a therapeutic strategy for colonic graft cancer in the future. J. Med. Invest. 66 : 190-193, February, 2019."},"publication_date":"2019","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.66","number":"No.1.2","starting_page":"190","ending_page":"193","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.66.190"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:19, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401415"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/115097","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/29892933","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1521699229821638272/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85038619573&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=349311","label":"url"}],"paper_title":{"en":"The effects of the herbal medicine Daikenchuto (TJ-100) after esophageal cancer resection, open-label, randomized controlled trial","ja":"The effects of the herbal medicine Daikenchuto (TJ-100) after esophageal cancer resection, open-label, randomized controlled trial"},"authors":{"en":[{"name":"Nishino Takeshi"},{"name":"Yoshida Takahiro"},{"name":"Goto Masakazu"},{"name":"Inoue Seiya"},{"name":"Minato Takuya"},{"name":"Fujiwara Satoshi"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Yuasa Yasuhiro"},{"name":"Yamai Hiromichi"},{"name":"Takechi Hirokazu"},{"name":"Toba Hiroaki"},{"name":"Takizawa Hiromitsu"},{"name":"Yoshida Mitsuteru"},{"name":"Seike Jun-ichi"},{"name":"Miyoshi Takanori"},{"name":"Tangoku Akira"}],"ja":[{"name":"西野 豪志"},{"name":"吉田 卓弘"},{"name":"後藤 正和"},{"name":"井上 聖也"},{"name":"湊 拓也"},{"name":"藤原 聡史"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"湯浅 康弘"},{"name":"山井 礼道"},{"name":"武知 浩和"},{"name":"鳥羽 博明"},{"name":"滝沢 宏光"},{"name":"吉田 光輝"},{"name":"清家 純一"},{"name":"三好 孝典"},{"name":"丹黒 章"}]},"description":{"en":"Daikenchuto (TJ-100), a traditional Japanese herbal medicine, is widely used in Japan. Its effects on gastrointestinal motility and microcirculation and its anti-inflammatory effect are known. The purpose of this prospective randomized controlled trial was to investigate the effect of TJ-100 after esophagectomy in esophageal cancer patients. Forty patients for whom subtotal esophageal resection for esophageal cancer was planned at our institute from March 2011 to August 2013 were enrolled and divided into two groups at the point of determination of the operation schedule after informed consent was obtained: a TJ-100 (15 g/day)-treated group (n = 20) and a control group (n = 20). The primary efficacy end-points were maintenance of the nutrition condition and the recovery of gastrointestinal function. The secondary efficacy end-points were the serum C-reactive protein (CRP) level and adrenomedullin level during the postoperative course, the incidence of postoperative complications, and the length of hospital stay after surgery. We examined 39 patients because one patient in the TJ-100 group was judged as having unresectable cancer after surgery. The mean age of the TJ-100 group patients was significantly older than that of the control group patients.The rate of body weight decrease at postoperative day 21 was significantly suppressed in the TJ-100 group (3.6% vs. the control group: 7.0%, p = 0.014), but the serum albumin level was not significantly different between the groups. The recovery of gastrointestinal function regarding flatus, defecation, and oral intake showed no significant between-group differences, but postoperative bowel symptoms tended to be rare in the TJ-100 group. There was no significant between-group difference in the length of hospital stay after surgery. The serum CRP level at postoperative day 3 was 4.9 mg/dl in the TJ-100 group and 6.9 mg/dl in the control group, showing a tendency of a suppressed serum CRP level in the TJ-100 group (p = 0.126). The rate of increase in adrenomedullin tended to be high postoperatively, but there was no significant difference between the two groups. TJ-100 treatment after esophageal cancer resection has the effects of prompting the recovery of gastrointestinal motility and minimizing body weight loss, and it might suppress the excess inflammatory reaction related to surgery.","ja":"Daikenchuto (TJ-100), a traditional Japanese herbal medicine, is widely used in Japan. Its effects on gastrointestinal motility and microcirculation and its anti-inflammatory effect are known. The purpose of this prospective randomized controlled trial was to investigate the effect of TJ-100 after esophagectomy in esophageal cancer patients. Forty patients for whom subtotal esophageal resection for esophageal cancer was planned at our institute from March 2011 to August 2013 were enrolled and divided into two groups at the point of determination of the operation schedule after informed consent was obtained: a TJ-100 (15 g/day)-treated group (n = 20) and a control group (n = 20). The primary efficacy end-points were maintenance of the nutrition condition and the recovery of gastrointestinal function. The secondary efficacy end-points were the serum C-reactive protein (CRP) level and adrenomedullin level during the postoperative course, the incidence of postoperative complications, and the length of hospital stay after surgery. We examined 39 patients because one patient in the TJ-100 group was judged as having unresectable cancer after surgery. The mean age of the TJ-100 group patients was significantly older than that of the control group patients.The rate of body weight decrease at postoperative day 21 was significantly suppressed in the TJ-100 group (3.6% vs. the control group: 7.0%, p = 0.014), but the serum albumin level was not significantly different between the groups. The recovery of gastrointestinal function regarding flatus, defecation, and oral intake showed no significant between-group differences, but postoperative bowel symptoms tended to be rare in the TJ-100 group. There was no significant between-group difference in the length of hospital stay after surgery. The serum CRP level at postoperative day 3 was 4.9 mg/dl in the TJ-100 group and 6.9 mg/dl in the control group, showing a tendency of a suppressed serum CRP level in the TJ-100 group (p = 0.126). The rate of increase in adrenomedullin tended to be high postoperatively, but there was no significant difference between the two groups. TJ-100 treatment after esophageal cancer resection has the effects of prompting the recovery of gastrointestinal motility and minimizing body weight loss, and it might suppress the excess inflammatory reaction related to surgery."},"publication_date":"2018-04","publication_name":{"en":"Esophagus","ja":"Esophagus"},"volume":"Vol.15","number":"No.2","starting_page":"75","ending_page":"82","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s10388-017-0601-9"],"issn":["1612-9067"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:20, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401416"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109690","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26577115","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84947424480&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=335758","label":"url"}],"paper_title":{"en":"CXCR4 Expression is Associated with Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma","ja":"CXCR4 Expression is Associated with Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma"},"authors":{"en":[{"name":"Goto Masakazu"},{"name":"Yoshida Takahiro"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Inoue Seiya"},{"name":"Fujiwara Satoshi"},{"name":"Kawakita Naoya"},{"name":"Nishino Takeshi"},{"name":"Minato Takuya"},{"name":"Yuasa Yasuhiro"},{"name":"Yamai Hiromichi"},{"name":"Takechi Hirokazu"},{"name":"Seike Jun-ichi"},{"name":"Bando Yoshimi"},{"name":"Tangoku Akira"}],"ja":[{"name":"後藤 正和"},{"name":"吉田 卓弘"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"井上 聖也"},{"name":"藤原 聡史"},{"name":"河北 直也"},{"name":"西野 豪志"},{"name":"湊 拓也"},{"name":"湯浅 康弘"},{"name":"山井 礼道"},{"name":"武知 浩和"},{"name":"清家 純一"},{"name":"坂東 良美"},{"name":"丹黒 章"}]},"description":{"en":"Chemokines and their receptors are known to play important roles in the tumorigenesis of many malignancies. The chemokine CXCL12 and its receptors CXCR4 and CXCR7 were suggested to be involved in cancer invasion and metastasis. The aim of this retrospective study was to evaluate the prognostic impact of the expressions of CXCL12, CXCR4 and CXCR7 in patients with esophageal squamous cell carcinoma (ESCC). We used immunohistochemistry (IHC) and reverse transcriptase-polymerase chain reaction (RT-PCR) to evaluate the expressions of CXCL12, CXCR4, and CXCR7 in ESCC patients' tumor biopsy specimens obtained during preoperative endoscopy or surgery. These results were compared with the patients' clinicopathological parameters and survival. IHC was conducted for 172 patients. High expression of CXCR4 in the cytoplasm and nuclei and that of CXCR7 were associated with poor cause-specific survival (CSS) (P= .002 and .010, respectively). The specimens from 52 of the 172 patients were examined by RT-PCR and quantitative real-time PCR. The expression levels of messenger RNA (mRNA) of CXCR4 and CXCR7 were significantly increased in the tumors compared with normal esophageal mucosae (P < .0001). The expression level of mRNA of CXCR4 was associated with poor recurrence-free survival and CSS (P = .012 and .038, respectively). CXCR4 expression is associated with poor prognosis in patients with ESCC.","ja":"Chemokines and their receptors are known to play important roles in the tumorigenesis of many malignancies. The chemokine CXCL12 and its receptors CXCR4 and CXCR7 were suggested to be involved in cancer invasion and metastasis. The aim of this retrospective study was to evaluate the prognostic impact of the expressions of CXCL12, CXCR4 and CXCR7 in patients with esophageal squamous cell carcinoma (ESCC). We used immunohistochemistry (IHC) and reverse transcriptase-polymerase chain reaction (RT-PCR) to evaluate the expressions of CXCL12, CXCR4, and CXCR7 in ESCC patients' tumor biopsy specimens obtained during preoperative endoscopy or surgery. These results were compared with the patients' clinicopathological parameters and survival. IHC was conducted for 172 patients. High expression of CXCR4 in the cytoplasm and nuclei and that of CXCR7 were associated with poor cause-specific survival (CSS) (P= .002 and .010, respectively). The specimens from 52 of the 172 patients were examined by RT-PCR and quantitative real-time PCR. The expression levels of messenger RNA (mRNA) of CXCR4 and CXCR7 were significantly increased in the tumors compared with normal esophageal mucosae (P < .0001). The expression level of mRNA of CXCR4 was associated with poor recurrence-free survival and CSS (P = .012 and .038, respectively). CXCR4 expression is associated with poor prognosis in patients with ESCC."},"publication_date":"2017-03","publication_name":{"en":"Annals of Surgical Oncology","ja":"Annals of Surgical Oncology"},"volume":"Vol.24","number":"No.3","starting_page":"832","ending_page":"840","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1245/s10434-015-4974-5"],"issn":["1534-4681"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:21, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401417"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109991","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84988359656&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=335750","label":"url"}],"paper_title":{"en":"Gender differences in clinicopathological features and prognosis of squamous cell carcinoma of the esophagus","ja":"Gender differences in clinicopathological features and prognosis of squamous cell carcinoma of the esophagus"},"authors":{"en":[{"name":"Nishino Takeshi"},{"name":"Yoshida Takahiro"},{"name":"Inoue Seiya"},{"name":"Fujiwara Satoshi"},{"name":"Goto Masakazu"},{"name":"Minato Takuya"},{"name":"Furukita Yoshihito"},{"name":"Yamamoto Yota"},{"name":"Yuasa Yasuhiro"},{"name":"Yamai Hiromichi"},{"name":"Takechi Hirokazu"},{"name":"Toba Hiroaki"},{"name":"Takizawa Hiromitsu"},{"name":"Yoshida Mitsuteru"},{"name":"Seike Jun-ichi"},{"name":"Miyoshi Takanori"},{"name":"Tangoku Akira"}],"ja":[{"name":"西野 豪志"},{"name":"吉田 卓弘"},{"name":"井上 聖也"},{"name":"藤原 聡史"},{"name":"後藤 正和"},{"name":"湊 拓也"},{"name":"古北 由仁"},{"name":"山本 洋太"},{"name":"湯浅 康弘"},{"name":"山井 礼道"},{"name":"武知 浩和"},{"name":"鳥羽 博明"},{"name":"滝沢 宏光"},{"name":"吉田 光輝"},{"name":"清家 純一"},{"name":"三好 孝典"},{"name":"丹黒 章"}]},"publication_date":"2017","publication_name":{"en":"Esophagus","ja":"Esophagus"},"volume":"Vol.14","number":"No.2","starting_page":"122","ending_page":"130","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s10388-016-0554-4"],"issn":["1612-9059"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:22, {"insert":{"user_id":"R000010822","type":"published_papers","id":"33229624"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111156","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/27040056","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=377730","label":"url"}],"paper_title":{"en":"Short-Term Outcomes of Laparoscopic Distal Gastrectomy for Advanced Gastric Cancer.","ja":"Short-Term Outcomes of Laparoscopic Distal Gastrectomy for Advanced Gastric Cancer."},"authors":{"en":[{"name":"Goto Masakazu"},{"name":"Okitsu Hiroshi"},{"name":"Yuasa Yasuhiro"},{"name":"Kuramoto Shunsuke"},{"name":"Tomibayashi Atsushi"},{"name":"Matsumoto Daisuke"},{"name":"Masuda Yuri"},{"name":"Edagawa Hiroshi"},{"name":"Tani Ryotaro"},{"name":"Mori Osamu"},{"name":"Matsuo Yuta"}],"ja":[{"name":"後藤 正和"},{"name":"沖津 宏"},{"name":"Yuasa Yasuhiro"},{"name":"Kuramoto Shunsuke"},{"name":"Tomibayashi Atsushi"},{"name":"松本 大資"},{"name":"Masuda Yuri"},{"name":"Edagawa Hiroshi"},{"name":"Tani Ryotaro"},{"name":"Mori Osamu"},{"name":"Matsuo Yuta"}]},"description":{"en":"The purpose of this study was to investigate the oncologic outcomes of laparoscopic distal gastrectomy (LDG) for advanced gastric cancer (AGC). Between April 2003 and March 2014, LDG was performed for 392 patients, 91 patients (23.2%) had histopathologically diagnosed AGC beyond T2 depth. The clinicopathological features, postoperative outcomes, mortality, morbidity, recurrence rate, and survivals of those patients were reviewed. The TNM stages of the tumor were IB in 26 patients (28.5%), IIA in 20 (21.9%), IIB in 18 (19.7%), IIIA in 13 (14.2%), IIIB in 6 (6.5%), IIIC in 6 (6.5%), and IV in 2 (2.1%). Major morbidity occurred in 14 patients (15.3%), with no postoperative mortality. Median follow-up was 24.5 months; 10 patients developed recurrence during the follow-up period, and 10 patients died, including 6 cancer deaths. The 5-year overall and disease-free survival rates were 76.8% and 72.6%, respectively. By stage, OS/DFS was 92.3%/91.8% in stage IB, 85.4%/85.4% in stage II, and 49.3%/26.9% in stage III. Oncologic outcomes were good in patients with AGC, especially with stage IB-IIB, who underwent LDG. LDG appears to be an effective approach for treating stage IB and II gastric cancer.","ja":"The purpose of this study was to investigate the oncologic outcomes of laparoscopic distal gastrectomy (LDG) for advanced gastric cancer (AGC). Between April 2003 and March 2014, LDG was performed for 392 patients, 91 patients (23.2%) had histopathologically diagnosed AGC beyond T2 depth. The clinicopathological features, postoperative outcomes, mortality, morbidity, recurrence rate, and survivals of those patients were reviewed. The TNM stages of the tumor were IB in 26 patients (28.5%), IIA in 20 (21.9%), IIB in 18 (19.7%), IIIA in 13 (14.2%), IIIB in 6 (6.5%), IIIC in 6 (6.5%), and IV in 2 (2.1%). Major morbidity occurred in 14 patients (15.3%), with no postoperative mortality. Median follow-up was 24.5 months; 10 patients developed recurrence during the follow-up period, and 10 patients died, including 6 cancer deaths. The 5-year overall and disease-free survival rates were 76.8% and 72.6%, respectively. By stage, OS/DFS was 92.3%/91.8% in stage IB, 85.4%/85.4% in stage II, and 49.3%/26.9% in stage III. Oncologic outcomes were good in patients with AGC, especially with stage IB-IIB, who underwent LDG. LDG appears to be an effective approach for treating stage IB and II gastric cancer."},"publication_date":"2016","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.63","number":"No.1-2","starting_page":"68","ending_page":"73","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.63.68"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:23, {"insert":{"user_id":"R000010822","type":"published_papers","id":"33229625"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111192","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/27644570","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=377729","label":"url"}],"paper_title":{"en":"Mesh-Airtight-Preperitoneum: a simple method for confirming mesh placement in transabdominal preperitoneal repair of inguinal hernia.","ja":"Mesh-Airtight-Preperitoneum: a simple method for confirming mesh placement in transabdominal preperitoneal repair of inguinal hernia."},"authors":{"en":[{"name":"Yuasa Yasuhiro"},{"name":"Okitsu Hiroshi"},{"name":"Goto Masakazu"},{"name":"Matsuo Yuta"},{"name":"Edagawa Hiroshi"},{"name":"Mori Osamu"},{"name":"Tani Ryotaro"},{"name":"Kuramoto Shunsuke"},{"name":"Ikeuchi Mayumi"},{"name":"Tomibayashi Atsushi"}],"ja":[{"name":"Yuasa Yasuhiro"},{"name":"沖津 宏"},{"name":"後藤 正和"},{"name":"Matsuo Yuta"},{"name":"Edagawa Hiroshi"},{"name":"Mori Osamu"},{"name":"Tani Ryotaro"},{"name":"Kuramoto Shunsuke"},{"name":"Ikeuchi Mayumi"},{"name":"Tomibayashi Atsushi"}]},"description":{"en":"We devised a method for confirming the position of mesh placed during transabdominal preperitoneal repair (TAPP) of an inguinal hernia. The preperitoneum is sufficiently detached, and the mesh is fixed in place as usual. Before completely closing the peritoneum, pressure is applied from outside the body and inside the abdominal cavity to remove as much air as possible from the detached preperitoneum; the peritoneum is then sutured using a V-Loc(TM) closure device so that it does not constrict. By releasing the pressure all at once, the airtightness of the preperitoneum is maintained, and the position of the mesh can be observed through the translucent peritoneum. This method, called Mesh-Airtight-Preperitoneum (MAPP), could become widely used as a simple technique for confirming mesh position in TAPP. J. Med. Invest. 63: 270-273, August, 2016.","ja":"We devised a method for confirming the position of mesh placed during transabdominal preperitoneal repair (TAPP) of an inguinal hernia. The preperitoneum is sufficiently detached, and the mesh is fixed in place as usual. Before completely closing the peritoneum, pressure is applied from outside the body and inside the abdominal cavity to remove as much air as possible from the detached preperitoneum; the peritoneum is then sutured using a V-Loc(TM) closure device so that it does not constrict. By releasing the pressure all at once, the airtightness of the preperitoneum is maintained, and the position of the mesh can be observed through the translucent peritoneum. This method, called Mesh-Airtight-Preperitoneum (MAPP), could become widely used as a simple technique for confirming mesh position in TAPP. J. Med. Invest. 63: 270-273, August, 2016."},"publication_date":"2016","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.63","number":"No.3-4","starting_page":"270","ending_page":"273","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.63.270"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:24, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30447519"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/26602406","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=363604","label":"url"}],"paper_title":{"en":"[A Case of Complete Pathological Response in a Patient with Locally Advanced Sigmoid Colon Cancer after FOLFOX IRI Chemotherapy].","ja":"[A Case of Complete Pathological Response in a Patient with Locally Advanced Sigmoid Colon Cancer after FOLFOX IRI Chemotherapy]."},"authors":{"en":[{"name":"Goto Masakazu"},{"name":"Okitsu Hiroshi"},{"name":"Yuasa Yasuhiro"},{"name":"Matsuo Yuta"},{"name":"Edagawa Hiroshi"},{"name":"Tani Ryotaro"},{"name":"Mori Osamu"},{"name":"Kuramoto Shunsuke"},{"name":"Tomibayashi Atsushi"},{"name":"Yamashita Michiko"},{"name":"Fujii Yoshiyuki"}],"ja":[{"name":"後藤 正和"},{"name":"沖津 宏"},{"name":"Yuasa Yasuhiro"},{"name":"Matsuo Yuta"},{"name":"Edagawa Hiroshi"},{"name":"Tani Ryotaro"},{"name":"Mori Osamu"},{"name":"Kuramoto Shunsuke"},{"name":"Tomibayashi Atsushi"},{"name":"山下 理子"},{"name":"Fujii Yoshiyuki"}]},"description":{"en":"A 61-year-old man with advanced sigmoid colon cancer was admitted to our hospital. Abdominal computed tomography (CT) revealed locally advanced sigmoid colon cancer, with suspected invasion of the bladder and small intestine. The clinical stage of the disease was T4b, N1, M0, and Stage III a, with wild-type KRAS expression. A transverse colostomy was performed because of the presence of a bowel obstruction. The patient received 4 courses of Leucovorin, 5-fluorouracil, oxaliplatin, and irinotecan (FOLFOXIRI). The size of the tumor and lymph nodes decreased noticeably after chemotherapy and laparoscopic high anterior resection with lymph node dissection. During this phase, the pathological stage of the disease was ypT0, N0, and Stage 0(no viable carcinoma cells, Grade 3). This result suggested that preoperative FOLFOXIRI chemotherapy is a useful regimen for the treatment of locally advanced colon cancer.","ja":"A 61-year-old man with advanced sigmoid colon cancer was admitted to our hospital. Abdominal computed tomography (CT) revealed locally advanced sigmoid colon cancer, with suspected invasion of the bladder and small intestine. The clinical stage of the disease was T4b, N1, M0, and Stage III a, with wild-type KRAS expression. A transverse colostomy was performed because of the presence of a bowel obstruction. The patient received 4 courses of Leucovorin, 5-fluorouracil, oxaliplatin, and irinotecan (FOLFOXIRI). The size of the tumor and lymph nodes decreased noticeably after chemotherapy and laparoscopic high anterior resection with lymph node dissection. During this phase, the pathological stage of the disease was ypT0, N0, and Stage 0(no viable carcinoma cells, Grade 3). This result suggested that preoperative FOLFOXIRI chemotherapy is a useful regimen for the treatment of locally advanced colon cancer."},"publication_date":"2015-11","publication_name":{"en":"Japanese Journal of Cancer and Chemotherapy","ja":"癌と化学療法"},"volume":"Vol.42","number":"No.11","starting_page":"1431","ending_page":"1434","languages":["jpn"],"referee":true,"identifiers":{"issn":["0385-0684"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:25, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401420"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/40019926421/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282763058189568/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=301476","label":"url"}],"paper_title":{"en":"Usefulness of lymphangiography with near infrared fluorescence system in treatment of postoperative chylothorax","ja":"乳び胸治療における近赤外蛍光システムを用いたリンパ官造影の有用性"},"authors":{"en":[{"name":"Goto Masakazu"},{"name":"Tangoku Akira"},{"name":"Takizawa Hiromitsu"},{"name":"Takechi Hirokazu"},{"name":"Furukita Yoshihito"}],"ja":[{"name":"後藤 正和"},{"name":"丹黒 章"},{"name":"滝沢 宏光"},{"name":"武知 浩和"},{"name":"古北 由仁"}]},"publication_date":"2014-01","publication_name":{"en":"Surgery","ja":"外科"},"volume":"Vol.76","number":"No.1","starting_page":"64","ending_page":"67","languages":["jpn"],"referee":true,"identifiers":{"issn":["0016-593X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:26, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401421"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/130004822718/","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109521","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/24705750","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001204244693120/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84897937797&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=280156","label":"url"}],"paper_title":{"en":"Glutamine protects the small intestinal mucosa in anticancer drug-induced rat enteritis model.","ja":"Glutamine protects the small intestinal mucosa in anticancer drug-induced rat enteritis model."},"authors":{"en":[{"name":"Takechi Hirokazu"},{"name":"Mawatari Kazuaki"},{"name":"Harada Nagakatsu"},{"name":"Nakaya Yutaka"},{"name":"Asakura Megumi"},{"name":"Aihara Mutsumi"},{"name":"Takizawa Hiromitsu"},{"name":"Goto Masakazu"},{"name":"Nishino Takeshi"},{"name":"Minato Takuya"},{"name":"Furukita Yoshihito"},{"name":"Yamamoto Yota"},{"name":"Yuasa Yasuhiro"},{"name":"Yamai Hiromichi"},{"name":"Yoshida Takahiro"},{"name":"Seike Jun-ichi"},{"name":"Tangoku Akira"}],"ja":[{"name":"武知 浩和"},{"name":"馬渡 一諭"},{"name":"原田 永勝"},{"name":"中屋 豊"},{"name":"Asakura Megumi"},{"name":"粟飯原 睦美"},{"name":"滝沢 宏光"},{"name":"後藤 正和"},{"name":"Nishino Takeshi"},{"name":"Minato Takuya"},{"name":"古北 由仁"},{"name":"山本 洋太"},{"name":"Yuasa Yasuhiro"},{"name":"Yamai Hiromichi"},{"name":"吉田 卓弘"},{"name":"清家 純一"},{"name":"丹黒 章"}]},"description":{"en":"Supportive therapy during chemotherapy has become essential, but effective preventive therapies to gastrointestinal mucosal injury are few. We investigated the efficacy of glutamine in rat anticancer drug-induced enteritis model. In this study, we used twenty male SD rats. They were divided into control, 5-fluorouracil (5-FU) (orally administered at 20 mg/kg day), 5-FU+glutamine (1000 mg/kg/day) and 5-FU+glutamine+fiber and oligosaccharide (GFO(®)) (1000 mg/kg/day) groups. All groups were sacrificed on day 6 and upper jejunums were excised. The jejunal villous height was measured in specimens. IgA level in jejunal washing solution, and serum diamine oxidase activity were also measured. The jejunal villous height was recognized as shorter in the specimen from 5-FU treated rats compared with 5-FU+glutamine treated rats (p<0.001). Serum diamine oxidase activity in 5-FU+glutamine group were significantly superior to that in 5-FU group (p=0.028). IgA level in jejunal washing solution tended to be higher in 5-FU+glutamine group than that in 5-FU group (p=0.076). On the other hand, serum diamine oxidase activity and IgA level in jejunal washing solution showed no significant difference between 5-FU+GFO and 5-FU treatment group. Our results suggest that glutamine showed protective effects on mucosal injury of small intestine in rat anticancer drug-induced enteritis model.","ja":"Supportive therapy during chemotherapy has become essential, but effective preventive therapies to gastrointestinal mucosal injury are few. We investigated the efficacy of glutamine in rat anticancer drug-induced enteritis model. In this study, we used twenty male SD rats. They were divided into control, 5-fluorouracil (5-FU) (orally administered at 20 mg/kg day), 5-FU+glutamine (1000 mg/kg/day) and 5-FU+glutamine+fiber and oligosaccharide (GFO(®)) (1000 mg/kg/day) groups. All groups were sacrificed on day 6 and upper jejunums were excised. The jejunal villous height was measured in specimens. IgA level in jejunal washing solution, and serum diamine oxidase activity were also measured. The jejunal villous height was recognized as shorter in the specimen from 5-FU treated rats compared with 5-FU+glutamine treated rats (p<0.001). Serum diamine oxidase activity in 5-FU+glutamine group were significantly superior to that in 5-FU group (p=0.028). IgA level in jejunal washing solution tended to be higher in 5-FU+glutamine group than that in 5-FU group (p=0.076). On the other hand, serum diamine oxidase activity and IgA level in jejunal washing solution showed no significant difference between 5-FU+GFO and 5-FU treatment group. Our results suggest that glutamine showed protective effects on mucosal injury of small intestine in rat anticancer drug-induced enteritis model."},"publication_date":"2014","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.61","number":"No.1-2","starting_page":"59","ending_page":"64","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.61.59"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:27, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401422"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23863591","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84977280371&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=265669","label":"url"}],"paper_title":{"en":"[Pathological Complete Response in a Case of Advanced Esophageal Cancer Invading Aorta Treated by Preoperative Chemotherapy with Docetaxel and Cisplatin plus 5-FU].","ja":"[Pathological Complete Response in a Case of Advanced Esophageal Cancer Invading Aorta Treated by Preoperative Chemotherapy with Docetaxel and Cisplatin plus 5-FU]."},"authors":{"en":[{"name":"Nishino Takeshi"},{"name":"Yamamoto Yota"},{"name":"Ikeda Mayumi"},{"name":"Morimoto Masami"},{"name":"Furukita Yoshihito"},{"name":"Goto Masakazu"},{"name":"Furukita Yoshihito"},{"name":"Takechi Hirokazu"},{"name":"Seike Junichi"},{"name":"Tangoku Akira"},{"name":"Fujiwara Haruo"}],"ja":[{"name":"西野 豪志"},{"name":"山本 洋太"},{"name":"Ikeda Mayumi"},{"name":"Morimoto Masami"},{"name":"古北 由仁"},{"name":"後藤 正和"},{"name":"古北 由仁"},{"name":"武知 浩和"},{"name":"Seike Junichi"},{"name":"丹黒 章"},{"name":"Fujiwara Haruo"}]},"description":{"en":"The patient was a 64-year-old man, diagnosed as cStage IVa esophageal cancer invading the aorta with lymph node metastasis. He received combination chemotherapy with docetaxel/cisplatin/5-FU(DFP therapy). After one course, CT and endoscopic examination showed remarkable reduction of the primary lesion and lymph node metastasis. We performed subtotal esophagectomy and gastric tube reconstruction by the retroposterior mediastinum route. The pathological specimen evidenced fibrosis and infiltration of inflammatory cells on almost all layers, but showed no viable malignant cells in the middle thoracic esophagus. Therefore, the pathological effect was judged as Grade 3(pCR). This case suggested that DFP combination chemotherapy may prove to be a useful treatment for advanced esophageal cancer with invasion to other organs.","ja":"The patient was a 64-year-old man, diagnosed as cStage IVa esophageal cancer invading the aorta with lymph node metastasis. He received combination chemotherapy with docetaxel/cisplatin/5-FU(DFP therapy). After one course, CT and endoscopic examination showed remarkable reduction of the primary lesion and lymph node metastasis. We performed subtotal esophagectomy and gastric tube reconstruction by the retroposterior mediastinum route. The pathological specimen evidenced fibrosis and infiltration of inflammatory cells on almost all layers, but showed no viable malignant cells in the middle thoracic esophagus. Therefore, the pathological effect was judged as Grade 3(pCR). This case suggested that DFP combination chemotherapy may prove to be a useful treatment for advanced esophageal cancer with invasion to other organs."},"publication_date":"2013-05","publication_name":{"en":"Japanese Journal of Cancer and Chemotherapy","ja":"Japanese Journal of Cancer and Chemotherapy"},"volume":"Vol.40","number":"No.5","starting_page":"643","ending_page":"646","languages":["eng"],"referee":true,"identifiers":{"issn":["0385-0684"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:28, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30496262"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264161","label":"url"}],"paper_title":{"en":"【エキスパートが教える内視鏡外科手術-ポイントとなる解剖の理解】 食道の鏡視下手術 食道癌に対する鏡視下手術 縦隔鏡下食道切除術","ja":"【エキスパートが教える内視鏡外科手術-ポイントとなる解剖の理解】 食道の鏡視下手術 食道癌に対する鏡視下手術 縦隔鏡下食道切除術"},"authors":{"en":[{"name":"Tangoku Akira"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Takechi Hirokazu"},{"name":"Goto Masakazu"},{"name":"西野 豪志"},{"name":"雅美 森本"}],"ja":[{"name":"丹黒 章"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"武知 浩和"},{"name":"後藤 正和"},{"name":"西野 豪志"},{"name":"雅美 森本"}]},"publication_date":"2013-05","publication_name":{"en":"Gastroenterological Surgery","ja":"消化器外科"},"volume":"Vol.36","number":"No.5","starting_page":"539","ending_page":"546","languages":["jpn"],"referee":true,"identifiers":{"issn":["0387-2645"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:29, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401424"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/40019669672/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1521699230614945408/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264165","label":"url"}],"paper_title":{"en":"術前化学放射線療法が奏効し喉頭温存手術が可能となった高度進行頸部食道類基底細胞癌の1例","ja":"術前化学放射線療法が奏効し喉頭温存手術が可能となった高度進行頸部食道類基底細胞癌の1例"},"authors":{"en":[{"name":"西野 豪志"},{"name":"Yamamoto Yota"},{"name":"Goto Masakazu"},{"name":"Furukita Yoshihito"},{"name":"Takechi Hirokazu"},{"name":"Tangoku Akira"}],"ja":[{"name":"西野 豪志"},{"name":"山本 洋太"},{"name":"後藤 正和"},{"name":"古北 由仁"},{"name":"武知 浩和"},{"name":"丹黒 章"}]},"publication_date":"2013-04","publication_name":{"en":"Operation","ja":"手術"},"volume":"Vol.67","number":"No.4","starting_page":"513","ending_page":"516","languages":["jpn"],"referee":true,"identifiers":{"issn":["0037-4423"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:30, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401425"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264171","label":"url"}],"paper_title":{"en":"【手術をめぐるがん看護∼意思決定支援から術後リハビリテーション看護まで∼】 --- (第I章)がん手術療法の\"いま\" がん手術療法の最前線","ja":"【手術をめぐるがん看護∼意思決定支援から術後リハビリテーション看護まで∼】 --- (第I章)がん手術療法の\"いま\" がん手術療法の最前線"},"authors":{"en":[{"name":"Tangoku Akira"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Goto Masakazu"},{"name":"西野 豪志"},{"name":"森本 雅美"}],"ja":[{"name":"丹黒 章"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"後藤 正和"},{"name":"西野 豪志"},{"name":"森本 雅美"}]},"publication_date":"2013-02","publication_name":{"en":"Japanese Journal of Cancer Care","ja":"がん看護"},"volume":"Vol.18","number":"No.2","starting_page":"111","ending_page":"113","languages":["jpn"],"referee":true,"identifiers":{"issn":["1342-0569"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:31, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401426"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/110009597504/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001204754813696/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264164","label":"url"}],"paper_title":{"en":"内科的治療抵抗性の乳児気管支肉芽に対してHo:YAGレーザー焼灼術を施行した1例","ja":"内科的治療抵抗性の乳児気管支肉芽に対してHo:YAGレーザー焼灼術を施行した1例"},"authors":{"en":[{"name":"池田 真由美"},{"name":"Takizawa Hiromitsu"},{"name":"古川 尊子"},{"name":"西野 豪志"},{"name":"Goto Masakazu"},{"name":"Kajiura Koichiro"},{"name":"Nakagawa Yasushi"},{"name":"Kawakami Yukikiyo"},{"name":"Yoshida Mitsuteru"},{"name":"Sakiyama Shoji"},{"name":"Kondo Kazuya"},{"name":"Tangoku Akira"}],"ja":[{"name":"池田 真由美"},{"name":"滝沢 宏光"},{"name":"古川 尊子"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"梶浦 耕一郎"},{"name":"中川 靖士"},{"name":"川上 行奎"},{"name":"吉田 光輝"},{"name":"先山 正二"},{"name":"近藤 和也"},{"name":"丹黒 章"}]},"publication_date":"2013-02","publication_name":{"en":"The Journal of the Japan Society for Respiratory Endoscopy","ja":"気管支学"},"volume":"Vol.35","number":"No.2","starting_page":"222","ending_page":"222","languages":["jpn"],"referee":true,"identifiers":{"issn":["0287-2137"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:32, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401427"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/110009597527/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282679731441664/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264162","label":"url"}],"paper_title":{"en":"YAGレーザー使用時の気管支鏡破損の1例","ja":"YAGレーザー使用時の気管支鏡破損の1例"},"authors":{"en":[{"name":"Kajiura Koichiro"},{"name":"Kawakami Yukikiyo"},{"name":"池田 真由美"},{"name":"古川 尊子"},{"name":"森本 雅美"},{"name":"西野 豪志"},{"name":"Goto Masakazu"},{"name":"Nakagawa Misako"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Takechi Hirokazu"},{"name":"Nakagawa Yasushi"},{"name":"Yoshida Mitsuteru"},{"name":"Takizawa Hiromitsu"},{"name":"Tadokoro Yukiko"},{"name":"Sakiyama Shoji"},{"name":"Kondo Kazuya"},{"name":"Tangoku Akira"}],"ja":[{"name":"梶浦 耕一郎"},{"name":"川上 行奎"},{"name":"池田 真由美"},{"name":"古川 尊子"},{"name":"森本 雅美"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"中川 美砂子"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"武知 浩和"},{"name":"中川 靖士"},{"name":"吉田 光輝"},{"name":"滝沢 宏光"},{"name":"田所 由紀子"},{"name":"先山 正二"},{"name":"近藤 和也"},{"name":"丹黒 章"}]},"publication_date":"2013-02","publication_name":{"en":"The Journal of the Japan Society for Respiratory Endoscopy","ja":"気管支学"},"volume":"Vol.35","number":"No.2","starting_page":"228","ending_page":"228","languages":["jpn"],"referee":true,"identifiers":{"issn":["0287-2137"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:33, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30496263"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264167","label":"url"}],"paper_title":{"en":"【消化器外科看護まるわかり いちからわかる!術前術後ケア・解剖・疾患・治療】 --- (第2章)消化器の解剖・疾患・術前術後ケア入門 食道の解剖生理，疾患，検査・治療","ja":"【消化器外科看護まるわかり いちからわかる!術前術後ケア・解剖・疾患・治療】 --- (第2章)消化器の解剖・疾患・術前術後ケア入門 食道の解剖生理，疾患，検査・治療"},"authors":{"en":[{"name":"Yamamoto Yota"},{"name":"Tangoku Akira"},{"name":"西野 豪志"},{"name":"Goto Masakazu"},{"name":"Furukita Yoshihito"},{"name":"Takechi Hirokazu"}],"ja":[{"name":"山本 洋太"},{"name":"丹黒 章"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"古北 由仁"},{"name":"武知 浩和"}]},"publication_date":"2013-01","publication_name":{"en":"Gastroenterological Surgery Nursing","ja":"消化器外科Nursing"},"volume":"Vol.18","number":"No.1","starting_page":"138","ending_page":"150","languages":["jpn"],"referee":true,"identifiers":{"issn":["1341-7819"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:34, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401429"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/40019481897/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1523106605546985088/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264155","label":"url"}],"paper_title":{"en":"胃食道逆流症と左腎癌に対して腹腔鏡下同時手術を施行した1例","ja":"胃食道逆流症と左腎癌に対して腹腔鏡下同時手術を施行した1例"},"authors":{"en":[{"name":"Furukita Yoshihito"},{"name":"森本 雅美"},{"name":"Goto Masakazu"},{"name":"Yamamoto Yota"},{"name":"Takechi Hirokazu"},{"name":"Tangoku Akira"}],"ja":[{"name":"古北 由仁"},{"name":"森本 雅美"},{"name":"後藤 正和"},{"name":"山本 洋太"},{"name":"武知 浩和"},{"name":"丹黒 章"}]},"publication_date":"2012-12","publication_name":{"en":"Operation","ja":"手術"},"volume":"Vol.66","number":"No.12","starting_page":"1779","ending_page":"1783","languages":["jpn"],"referee":true,"identifiers":{"issn":["0037-4423"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:35, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401430"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264154","label":"url"}],"paper_title":{"en":"腹腔鏡下手術を施行したupside down stomachを呈する食道裂孔ヘルニアの1例","ja":"腹腔鏡下手術を施行したupside down stomachを呈する食道裂孔ヘルニアの1例"},"authors":{"en":[{"name":"Furukita Yoshihito"},{"name":"森本 雅美"},{"name":"Goto Masakazu"},{"name":"Yamamoto Yota"},{"name":"Takechi Hirokazu"},{"name":"Tangoku Akira"}],"ja":[{"name":"古北 由仁"},{"name":"森本 雅美"},{"name":"後藤 正和"},{"name":"山本 洋太"},{"name":"武知 浩和"},{"name":"丹黒 章"}]},"publication_date":"2012-11","publication_name":{"en":"Journal of Japan Surgical Association","ja":"日本臨床外科学会雑誌"},"volume":"Vol.73","number":"No.11","starting_page":"2813","ending_page":"2818","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.3919/jjsa.73.2813"],"issn":["1345-2843"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:36, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401431"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10031123692/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282679827435520/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264157","label":"url"}],"paper_title":{"en":"MEDIASTINOSCOPE-ASSISTED TRANSHIATAL ESOPHAGECTOMY FOR SUPERFICIAL ESOPHAGEAL CANCER DEVELOPED AFTER LEFT THORACOPLASTY : REPORT OF A CASE","ja":"縦隔鏡下食道切除術を行った左胸郭成形術後食道表在癌の1例"},"authors":{"en":[{"name":"Goto Masakazu"},{"name":"Tangoku Akira"},{"name":"Yamamoto Yota"},{"name":"雅美 森本"},{"name":"Furukita Yoshihito"},{"name":"Takechi Hirokazu"}],"ja":[{"name":"後藤 正和"},{"name":"丹黒 章"},{"name":"山本 洋太"},{"name":"雅美 森本"},{"name":"古北 由仁"},{"name":"武知 浩和"}]},"publication_date":"2012-07-25","publication_name":{"en":"Journal of Japan Surgical Association","ja":"日本臨床外科学会雑誌"},"volume":"Vol.73","number":"No.7","starting_page":"1659","ending_page":"1663","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.3919/jjsa.73.1659"],"issn":["1345-2843"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:37, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401433"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10030789434/","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/22790989","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001204727960320/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=258439","label":"url"}],"paper_title":{"en":"The New Era of Staging as a Key for an Appropriate Treatment for Esophageal Cancer","ja":"The New Era of Staging as a Key for an Appropriate Treatment for Esophageal Cancer"},"authors":{"en":[{"name":"Tangoku Akira"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Goto Masakazu"},{"name":"Morimoto Masami"}],"ja":[{"name":"丹黒 章"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"後藤 正和"},{"name":"森本 雅美"}]},"description":{"en":"Fluorodeoxyglucose-positron emission tomography (FDG-PET) and computed tomography (CT) have become the gold standard for staging of esophageal cancer by detecting distant metastases, but metastatic lymph nodes are often difficult to diagnose from the size and standardized uptake value (SUV). If we compare the diagnostic performance of endoscopic ultrasonography (EUS), CT, and FDG-PET in staging of esophageal cancer, EUS is the most sensitive method to identify the detection of regional lymph node metastases, whereas CT and FDG-PET are more specific tests. Combination study with CT, EUS and PETCT cannot make a precise diagnosis after neoadjuvant therapy (NAT). A precise staging might be determined by the fine needle aspiration biopsy (FNAB) under EUS and US screening in the neck and the abdomen even after NAT. Indication of endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) for superficial cancer is sensitive because of difficulty in T1b cancer diagnosis. Detailed examination about vessel invasion and the possibility of residual tumor with dissected specimen will offer an appropriate additional therapy. New strategy like sentinel lymph node (SLN) navigation could supply more information about lymphatic routes and metastatic nodes. SLN navigation with ESD might become a new less invasive strategy for superficial esophageal cancer.","ja":"Fluorodeoxyglucose-positron emission tomography (FDG-PET) and computed tomography (CT) have become the gold standard for staging of esophageal cancer by detecting distant metastases, but metastatic lymph nodes are often difficult to diagnose from the size and standardized uptake value (SUV). If we compare the diagnostic performance of endoscopic ultrasonography (EUS), CT, and FDG-PET in staging of esophageal cancer, EUS is the most sensitive method to identify the detection of regional lymph node metastases, whereas CT and FDG-PET are more specific tests. Combination study with CT, EUS and PETCT cannot make a precise diagnosis after neoadjuvant therapy (NAT). A precise staging might be determined by the fine needle aspiration biopsy (FNAB) under EUS and US screening in the neck and the abdomen even after NAT. Indication of endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) for superficial cancer is sensitive because of difficulty in T1b cancer diagnosis. Detailed examination about vessel invasion and the possibility of residual tumor with dissected specimen will offer an appropriate additional therapy. New strategy like sentinel lymph node (SLN) navigation could supply more information about lymphatic routes and metastatic nodes. SLN navigation with ESD might become a new less invasive strategy for superficial esophageal cancer."},"publication_date":"2012-06-01","publication_name":{"en":"Annals of Thoracic and Cardiovascular Surgery","ja":"Annals of Thoracic and Cardiovascular Surgery"},"volume":"Vol.18","number":"No.3","starting_page":"190","ending_page":"199","languages":["eng"],"referee":true,"identifiers":{"doi":["10.5761/atcs.ra.12.01926"],"issn":["1341-1098"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:38, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401434"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10030988380/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001204852799872/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264158","label":"url"}],"paper_title":{"en":"A CASE OF CONGENTIAL ESOPHAGOBRONCHIAL FISTULA IN AN ADULT WITH IMPAIRED PULMONARY FUNCTION WHO WAS TREATED USING FISTULECTOMY AND RIGHT MIDDLE AND LOWER LOBECTOMY","ja":"右中下葉・瘻管切除を施行した低肺機能の成人先天性食道気管支瘻の1例"},"authors":{"en":[{"name":"Goto Masakazu"},{"name":"Sakiyama Shoji"},{"name":"Toba Hiroaki"},{"name":"Kenzaki Koichiro"},{"name":"Kondo Kazuya"},{"name":"Tangoku Akira"}],"ja":[{"name":"後藤 正和"},{"name":"先山 正二"},{"name":"鳥羽 博明"},{"name":"監﨑 孝一郎"},{"name":"近藤 和也"},{"name":"丹黒 章"}]},"publication_date":"2012-05-25","publication_name":{"en":"Journal of Japan Surgical Association","ja":"日本臨床外科学会雑誌"},"volume":"Vol.73","number":"No.5","starting_page":"1075","ending_page":"1079","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.3919/jjsa.73.1075"],"issn":["1345-2843"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:39, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401435"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=267321","label":"url"}],"paper_title":{"en":"【必読 イレウスの診断から治療まで】機械的イレウス 複雑性または絞扼性イレウス ヘルニア嵌頓","ja":"【必読 イレウスの診断から治療まで】機械的イレウス 複雑性または絞扼性イレウス ヘルニア嵌頓"},"authors":{"en":[{"name":"Sato Horohiko"},{"name":"Shimada Mitsuo"},{"name":"Kurita Nobuhiro"},{"name":"Iwata Takashi"},{"name":"Nishioka Masanori"},{"name":"Morimoto Shinya"},{"name":"Yoshikawa Kouzou"},{"name":"Miyatani Tomohiko"},{"name":"Goto Masakazu"},{"name":"柏原 秀也"},{"name":"Takasu Chie"}],"ja":[{"name":"佐藤 宏彦"},{"name":"島田 光生"},{"name":"栗田 信浩"},{"name":"岩田 貴"},{"name":"西岡 将規"},{"name":"森本 慎也"},{"name":"吉川 幸造"},{"name":"宮谷 知彦"},{"name":"後藤 正和"},{"name":"柏原 秀也"},{"name":"髙須 千絵"}]},"publication_date":"2012-05","publication_name":{"en":"Surgery","ja":"外科"},"volume":"Vol.74","number":"No.3","starting_page":"273","ending_page":"278","languages":["jpn"],"referee":true,"identifiers":{"issn":["0016-593X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:40, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401436"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/40019553441/","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/110365","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1050282812441819136/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264169","label":"url"}],"paper_title":{"en":"Erlotinibでinduction therapyを行ったIIIA期非小細胞肺癌の1手術例","ja":"Erlotinibでinduction therapyを行ったIIIA期非小細胞肺癌の1手術例"},"authors":{"en":[{"name":"坂本 晋一"},{"name":"Kajiura Koichiro"},{"name":"Takizawa Hiromitsu"},{"name":"Nakagawa Yasushi"},{"name":"池田 真由美"},{"name":"古川 尊子"},{"name":"森本 雅美"},{"name":"西野 豪志"},{"name":"Goto Masakazu"},{"name":"Nakagawa Misako"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Takechi Hirokazu"},{"name":"Yoshida Mitsuteru"},{"name":"Kawakami Yukikiyo"},{"name":"Tadokoro Yukiko"},{"name":"Sakiyama Shoji"},{"name":"Kondo Kazuya"},{"name":"Bando Yoshimi"},{"name":"岡崎 弘泰"},{"name":"Goto Hisatsugu"},{"name":"Nishioka Yasuhiko"},{"name":"Tangoku Akira"}],"ja":[{"name":"坂本 晋一"},{"name":"梶浦 耕一郎"},{"name":"滝沢 宏光"},{"name":"中川 靖士"},{"name":"池田 真由美"},{"name":"古川 尊子"},{"name":"森本 雅美"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"中川 美砂子"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"武知 浩和"},{"name":"吉田 光輝"},{"name":"川上 行奎"},{"name":"田所 由紀子"},{"name":"先山 正二"},{"name":"近藤 和也"},{"name":"坂東 良美"},{"name":"岡崎 弘泰"},{"name":"後東 久嗣"},{"name":"西岡 安彦"},{"name":"丹黒 章"}]},"publication_date":"2012-05","publication_name":{"en":"Shikoku Acta Medica","ja":"四国医学雑誌"},"volume":"Vol.68","number":"No.5-6","starting_page":"251","ending_page":"256","languages":["jpn"],"referee":true,"identifiers":{"issn":["0037-3699"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:41, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401437"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10030762027/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001204850918784/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=258417","label":"url"}],"paper_title":{"en":"Reoperation for recurrence and complications after nissen fundoplication","ja":"Nissen噴門形成術後の再発・合併症に対する再手術の経験"},"authors":{"en":[{"name":"Furukita Yoshihito"},{"name":"森本 雅美"},{"name":"Goto Masakazu"},{"name":"Yamamoto Yota"},{"name":"Takechi Hirokazu"},{"name":"Tangoku Akira"}],"ja":[{"name":"古北 由仁"},{"name":"森本 雅美"},{"name":"後藤 正和"},{"name":"山本 洋太"},{"name":"武知 浩和"},{"name":"丹黒 章"}]},"publication_date":"2012-03-25","publication_name":{"en":"Journal of Japan Surgical Association","ja":"日本臨床外科学会雑誌"},"volume":"Vol.73","number":"No.3","starting_page":"527","ending_page":"531","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.3919/jjsa.73.527"],"issn":["1345-2843"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:42, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401438"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/22847125","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84871802319&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=255288","label":"url"}],"paper_title":{"en":"Aldehyde Dehydrogenase 1 Expression is Associated with Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma.","ja":"Aldehyde Dehydrogenase 1 Expression is Associated with Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma."},"authors":{"en":[{"name":"Minato Takuya"},{"name":"Yamamoto Yota"},{"name":"Seike Jun-ichi"},{"name":"Yoshida Takahiro"},{"name":"Yamai Hiromichi"},{"name":"Takechi Hirokazu"},{"name":"Yuasa Yasuhiro"},{"name":"Furukita Yoshihito"},{"name":"Goto Masakazu"},{"name":"Bando Yoshimi"},{"name":"Tangoku Akira"}],"ja":[{"name":"Minato Takuya"},{"name":"山本 洋太"},{"name":"清家 純一"},{"name":"吉田 卓弘"},{"name":"Yamai Hiromichi"},{"name":"武知 浩和"},{"name":"Yuasa Yasuhiro"},{"name":"古北 由仁"},{"name":"後藤 正和"},{"name":"坂東 良美"},{"name":"丹黒 章"}]},"description":{"en":"Aldehyde dehydrogenase 1 (ALDH1) and CD44 act as important biomarkers in several solid tumors. However, few studies have examined the relationships between ALDH1 expression and the prognosis and clinical characteristics of esophageal squamous cell carcinoma (ESCC). This study was a retrospective case-control study and included 152 patients with ESCC. A total of 56 patients underwent surgery (OP group), 40 patients received neoadjuvant chemotherapy involving weekly docetaxel plus 5-fluorouracil and low-dose cisplatin (DFP therapy) prior to undergoing surgery (NAC group), and 56 patients received initial systemic DFP therapy (CT group). The ALDH1 and CD44 immunohistochemical expression levels of each tumor were evaluated and compared with the prognosis and clinical characteristics of the ESCC patients. In the OP and NAC groups, multivariate analysis found that ALDH1 was independently associated with postoperative recurrence and prognosis (OP group, P=0.004 and 0.016, respectively; NAC group, P=0.026 and 0.014, respectively). In addition, CD44 was found to be associated with postoperative recurrence in the OP group and prognosis in the NAC group (P=0.024 and 0.047, respectively). Among the ALDH1-negative clinical stage II/III patients, the OP and NAC groups displayed better prognoses than the CT group (P<0.001). However, among the ALDH1-positive clinical stage II/III patients, the OP and NAC groups displayed poorer prognoses than the CT group (P=0.049). ALDH1 was found to be a predictor of postoperative recurrence and prognosis in ESCC, and CD44 might be a predictor of recurrence and prognosis. ALDH1 expression might affect the treatment strategy for ESCC.","ja":"BACKGROUND: Aldehyde dehydrogenase 1 (ALDH1) and CD44 act as important biomarkers in several solid tumors. However, few studies have examined the relationships between ALDH1 expression and the prognosis and clinical characteristics of esophageal squamous cell carcinoma (ESCC). METHODS: This study was a retrospective case-control study and included 152 patients with ESCC. A total of 56 patients underwent surgery (OP group), 40 patients received neoadjuvant chemotherapy involving weekly docetaxel plus 5-fluorouracil and low-dose cisplatin (DFP therapy) prior to undergoing surgery (NAC group), and 56 patients received initial systemic DFP therapy (CT group). The ALDH1 and CD44 immunohistochemical expression levels of each tumor were evaluated and compared with the prognosis and clinical characteristics of the ESCC patients. RESULTS: In the OP and NAC groups, multivariate analysis found that ALDH1 was independently associated with postoperative recurrence and prognosis (OP group, P = 0.004 and 0.016, respectively; NAC group, P = 0.026 and 0.014, respectively). In addition, CD44 was found to be associated with postoperative recurrence in the OP group and prognosis in the NAC group (P = 0.024 and 0.047, respectively). Among the ALDH1-negative clinical stage II/III patients, the OP and NAC groups displayed better prognoses than the CT group (P < 0.001). However, among the ALDH1-positive clinical stage II/III patients, the OP and NAC groups displayed poorer prognoses than the CT group (P = 0.049). CONCLUSIONS: ALDH1 was found to be a predictor of postoperative recurrence and prognosis in ESCC, and CD44 might be a predictor of recurrence and prognosis. ALDH1 expression might affect the treatment strategy for ESCC."},"publication_date":"2012-01","publication_name":{"en":"Annals of Surgical Oncology","ja":"Annals of Surgical Oncology"},"volume":"Vol.20","number":"No.1","starting_page":"209","ending_page":"217","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1245/s10434-012-2535-8"],"issn":["1534-4681"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:43, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401439"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=258434","label":"url"}],"paper_title":{"en":"内視鏡外科医のための微細局所解剖アトラス 縦隔鏡を用いた経裂孔的食道切除術","ja":"内視鏡外科医のための微細局所解剖アトラス 縦隔鏡を用いた経裂孔的食道切除術"},"authors":{"en":[{"name":"Tangoku Akira"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Takechi Hirokazu"},{"name":"Goto Masakazu"},{"name":"森本 雅美"}],"ja":[{"name":"丹黒 章"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"武知 浩和"},{"name":"後藤 正和"},{"name":"森本 雅美"}]},"publication_date":"2012","publication_name":{"en":"Operation","ja":"手術"},"volume":"Vol.66","number":"No.6","starting_page":"665","ending_page":"673","languages":["jpn"],"referee":true,"identifiers":{"issn":["0037-4423"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:44, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401440"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=258432","label":"url"}],"paper_title":{"en":"食道癌の姑息的治療(ステント治療，バイパス手術)","ja":"食道癌の姑息的治療(ステント治療，バイパス手術)"},"authors":{"en":[{"name":"Tangoku Akira"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Goto Masakazu"},{"name":"西野 豪志"},{"name":"森本 雅美"},{"name":"古川 尊子"},{"name":"池田 真由美"},{"name":"山崎 裕行"}],"ja":[{"name":"丹黒 章"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"後藤 正和"},{"name":"西野 豪志"},{"name":"森本 雅美"},{"name":"古川 尊子"},{"name":"池田 真由美"},{"name":"山崎 裕行"}]},"publication_date":"2012","publication_name":{"en":"コンセンサス癌治療","ja":"コンセンサス癌治療"},"volume":"Vol.11","number":"No.2","starting_page":"103","ending_page":"109","languages":["jpn"],"referee":true,"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:45, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401441"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/21792510","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=255298","label":"url"}],"paper_title":{"en":"Sentinel lymph node biopsy using intraoperative indocyanine green fluorescence imaging navigated with preoperative CT lymphography for superficial esophageal cancer.","ja":"Sentinel lymph node biopsy using intraoperative indocyanine green fluorescence imaging navigated with preoperative CT lymphography for superficial esophageal cancer."},"authors":{"en":[{"name":"Yuasa Yasuhiro"},{"name":"Seike Junichi"},{"name":"Yoshida Takahiro"},{"name":"Takechi Hirokazu"},{"name":"Yamai Hiromichi"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Goto Masakazu"},{"name":"Minato Takuya"},{"name":"Nishino Takeshi"},{"name":"Inoue Seiya"},{"name":"Fujiwara Satoshi"},{"name":"Tangoku Akira"}],"ja":[{"name":"Yuasa Yasuhiro"},{"name":"Seike Junichi"},{"name":"吉田 卓弘"},{"name":"武知 浩和"},{"name":"Yamai Hiromichi"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"後藤 正和"},{"name":"Minato Takuya"},{"name":"Nishino Takeshi"},{"name":"Inoue Seiya"},{"name":"Fujiwara Satoshi"},{"name":"丹黒 章"}]},"description":{"en":"Preoperative CTLG visualized the correct number and site of SLNs in surrounding anatomy during routine computed tomography to evaluate distant metastases. Referring to CTLG, SLNs were identified using IGFI, resulting in successful SLN navigation and saving time and cost. This method appears clinically applicable as a less-invasive method for treating superficial esophageal cancer.","ja":"Preoperative CTLG visualized the correct number and site of SLNs in surrounding anatomy during routine computed tomography to evaluate distant metastases. Referring to CTLG, SLNs were identified using IGFI, resulting in successful SLN navigation and saving time and cost. This method appears clinically applicable as a less-invasive method for treating superficial esophageal cancer."},"publication_date":"2011-07-27","publication_name":{"en":"Annals of Surgical Oncology","ja":"Annals of Surgical Oncology"},"volume":"Vol.19","number":"No.2","starting_page":"486","ending_page":"493","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1245/s10434-011-1922-x"],"issn":["1534-4681"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:46, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401442"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/40018847910/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001288081414144/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=258431","label":"url"}],"paper_title":{"en":"A case of appendiceal mucinous cystadenoma with high serum carcinoembryonic antigen level on which laparoscopic ileocecal resection was performed","ja":"高癌胎児性抗原(CEA)血症を伴う虫垂粘液嚢胞腺腫の1例"},"authors":{"en":[{"name":"Furukita Yoshihito"},{"name":"Goto Masakazu"},{"name":"西野 豪志"},{"name":"福井 康雄"},{"name":"谷木 利勝"},{"name":"堀見 忠司"}],"ja":[{"name":"古北 由仁"},{"name":"後藤 正和"},{"name":"西野 豪志"},{"name":"福井 康雄"},{"name":"谷木 利勝"},{"name":"堀見 忠司"}]},"publication_date":"2011-06","publication_name":{"en":"Surgery","ja":"外科"},"volume":"Vol.73","number":"No.6","starting_page":"648","ending_page":"652","languages":["jpn"],"referee":true,"identifiers":{"issn":["0016-593X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:47, {"insert":{"user_id":"R000010822","type":"published_papers","id":"33229626"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/18936671","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=377731","label":"url"}],"paper_title":{"en":"Laparoscopic permanent sigmoid stoma creation through the extraperitoneal route.","ja":"Laparoscopic permanent sigmoid stoma creation through the extraperitoneal route."},"authors":{"en":[{"name":"Hamada Madoka"},{"name":"Nishioka Yutaka"},{"name":"Nishimura Takao"},{"name":"Goto Masakazu"},{"name":"Furukita Yoshihito"},{"name":"Ozaki Kazuhide"},{"name":"Nakamura Toshio"},{"name":"Fukui Yasuo"},{"name":"Taniki Toshikatsu"},{"name":"Horimi Tadashi"}],"ja":[{"name":"Hamada Madoka"},{"name":"西岡 豊"},{"name":"Nishimura Takao"},{"name":"後藤 正和"},{"name":"古北 由仁"},{"name":"Ozaki Kazuhide"},{"name":"Nakamura Toshio"},{"name":"Fukui Yasuo"},{"name":"Taniki Toshikatsu"},{"name":"Horimi Tadashi"}]},"description":{"en":"About 50% of patients who have a permanent stoma experience some degree of parastomal hernia formation. To prevent this complication, the extraperitoneal route is considered to be more effective than the transperitoneal route in the case of open colorectal surgery. This technique also has superiority in avoiding postoperative intestinal obstruction. Although laparoscopic surgery for rectal cancer has not been proved to be as safe as open surgery by a randomized-controlled trial, some studies have shown the equality of long-term results with laparoscopic low anterior resection and laparoscopic abdominoperineal resection. It is anticipated that cases of laparoscopic abdominoperineal resection will increase in the near future. However, a laparoscopic technique for creation of a permanent stoma has hardly been discussed. Most operative procedures for laparoscopic stoma creation have been performed with transperitoneal route, which may cause parastomal hernia and/or intestinal obstruction. This report describes a laparoscopic technique for permanent sigmoid stoma creation through the extraperitoneal approach.","ja":"About 50% of patients who have a permanent stoma experience some degree of parastomal hernia formation. To prevent this complication, the extraperitoneal route is considered to be more effective than the transperitoneal route in the case of open colorectal surgery. This technique also has superiority in avoiding postoperative intestinal obstruction. Although laparoscopic surgery for rectal cancer has not been proved to be as safe as open surgery by a randomized-controlled trial, some studies have shown the equality of long-term results with laparoscopic low anterior resection and laparoscopic abdominoperineal resection. It is anticipated that cases of laparoscopic abdominoperineal resection will increase in the near future. However, a laparoscopic technique for creation of a permanent stoma has hardly been discussed. Most operative procedures for laparoscopic stoma creation have been performed with transperitoneal route, which may cause parastomal hernia and/or intestinal obstruction. This report describes a laparoscopic technique for permanent sigmoid stoma creation through the extraperitoneal approach."},"publication_date":"2008-10","publication_name":{"en":"Surgical Laparoscopy, Endoscopy & Percutaneous Techniques","ja":"Surgical Laparoscopy, Endoscopy & Percutaneous Techniques"},"volume":"Vol.18","number":"No.5","starting_page":"483","ending_page":"485","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1097/SLE.0b013e3181805729"],"issn":["1534-4908"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:48, {"insert":{"user_id":"R000010822","type":"published_papers","id":"40416144"},"force":{"see_also":[{"@id":"https://cir.nii.ac.jp/crid/1050282812999350400/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=392681","label":"url"}],"paper_title":{"en":"Epstein-Barr virus-positive gastric cancer with lymph node metastasis : a case report","ja":"リンパ節転移を伴った Epstein-Barr virus 関連胃癌の1例"},"authors":{"en":[{"name":"住友, 弘幸"},{"name":"Okitsu Hiroshi"},{"name":"増田, 有理"},{"name":"藏本, 俊輔"},{"name":"Matsumoto Daisuke"},{"name":"富林, 敦司"},{"name":"浜田, 陽子"},{"name":"Goto Masakazu"},{"name":"湯浅, 康弘"},{"name":"川中, 妙子"},{"name":"石倉, 久嗣"},{"name":"木村, 秀"},{"name":"阪田, 章聖"},{"name":"Yamashita Michiko"},{"name":"藤井, 義幸"}],"ja":[{"name":"住友, 弘幸"},{"name":"沖津 宏"},{"name":"増田, 有理"},{"name":"藏本, 俊輔"},{"name":"松本 大資"},{"name":"富林, 敦司"},{"name":"浜田, 陽子"},{"name":"後藤 正和"},{"name":"湯浅, 康弘"},{"name":"川中, 妙子"},{"name":"石倉, 久嗣"},{"name":"木村, 秀"},{"name":"阪田, 章聖"},{"name":"山下 理子"},{"name":"藤井, 義幸"}]},"publication_date":"2014-03-01","publication_name":{"en":"Tokushima Red Cross Hospital Medical Journal","ja":"徳島赤十字病院医学雑誌"},"volume":"Vol.19","number":"No.1","starting_page":"44","ending_page":"48","languages":["jpn"],"identifiers":{"issn":["1346-9878"]},"published_paper_type":"research_institution"},"priority":"input_data"}
line:49, {"insert":{"user_id":"R000010822","type":"published_papers","id":"40416145"},"force":{"see_also":[{"@id":"https://cir.nii.ac.jp/crid/1050001338022642304/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=392680","label":"url"}],"paper_title":{"en":"長期間自然経過を追えた早期肺癌の1例","ja":"長期間自然経過を追えた早期肺癌の1例"},"authors":{"en":[{"name":"Matsumoto Daisuke"},{"name":"木村, 秀"},{"name":"石倉, 久嗣"},{"name":"松岡, 裕"},{"name":"増田, 有理"},{"name":"藏本, 俊輔"},{"name":"富林, 敦司"},{"name":"Goto Masakazu"},{"name":"浜田, 陽子"},{"name":"湯浅, 康弘"},{"name":"川中, 妙子"},{"name":"Okitsu Hiroshi"},{"name":"阪田, 章聖"},{"name":"Yamashita Michiko"},{"name":"藤井, 義幸"}],"ja":[{"name":"松本 大資"},{"name":"木村, 秀"},{"name":"石倉, 久嗣"},{"name":"松岡, 裕"},{"name":"増田, 有理"},{"name":"藏本, 俊輔"},{"name":"富林, 敦司"},{"name":"後藤 正和"},{"name":"浜田, 陽子"},{"name":"湯浅, 康弘"},{"name":"川中, 妙子"},{"name":"沖津 宏"},{"name":"阪田, 章聖"},{"name":"山下 理子"},{"name":"藤井, 義幸"}]},"publication_date":"2014-03-01","publication_name":{"en":"Tokushima Red Cross Hospital Medical Journal","ja":"徳島赤十字病院医学雑誌"},"volume":"Vol.19","number":"No.1","starting_page":"76","ending_page":"79","languages":["jpn"],"identifiers":{"issn":["1346-9878"]},"published_paper_type":"research_institution"},"priority":"input_data"}
line:50, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401443"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/40019800041/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1524232505259609728/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=274948","label":"url"}],"paper_title":{"en":"特集 食道疾患手術のすべて Ⅱ．悪性疾患の手術 5．縦隔鏡補助下経裂孔的食道切除術","ja":"特集 食道疾患手術のすべて Ⅱ．悪性疾患の手術 5．縦隔鏡補助下経裂孔的食道切除術"},"authors":{"en":[{"name":"Tangoku Akira"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Takechi Hirokazu"},{"name":"Goto Masakazu"},{"name":"西野 豪志"},{"name":"坂本 晋一"}],"ja":[{"name":"丹黒 章"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"武知 浩和"},{"name":"後藤 正和"},{"name":"西野 豪志"},{"name":"坂本 晋一"}]},"publication_date":"2013-09","publication_name":{"en":"Operation","ja":"Operation"},"volume":"Vol.67","number":"No.10","starting_page":"1435","ending_page":"1440","languages":["deu"],"identifiers":{"issn":["0037-4423"]},"published_paper_type":"research_institution"},"priority":"input_data"}
line:51, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30401444"},"force":{"see_also":[{"@id":"http://repo.lib.tokushima-u.ac.jp/109632","label":"url"},{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/109632","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1050564287418399360/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=274911","label":"url"}],"paper_title":{"en":"Two patients managed by palliative care for symptoms due to cervical lymph node recurrence of esophageal carcinoma","ja":"食道癌頸部リンパ節再発による症状に対して緩和ケアを実践した2症例"},"authors":{"en":[{"name":"Takechi Hirokazu"},{"name":"坂本 晋一"},{"name":"森下 敦司"},{"name":"Goto Masakazu"},{"name":"西野 豪志"},{"name":"Furukita Yoshihito"},{"name":"Yamamoto Yota"},{"name":"Yoshida Takahiro"},{"name":"Seike Jun-ichi"},{"name":"Takizawa Hiromitsu"},{"name":"Tangoku Akira"}],"ja":[{"name":"武知 浩和"},{"name":"坂本 晋一"},{"name":"森下 敦司"},{"name":"後藤 正和"},{"name":"西野 豪志"},{"name":"古北 由仁"},{"name":"山本 洋太"},{"name":"吉田 卓弘"},{"name":"清家 純一"},{"name":"滝沢 宏光"},{"name":"丹黒 章"}]},"description":{"en":"Our department aggressively performs initial treatment for esophageal carcinoma with multidisciplinary approaches, and not only positively treats patients with recurrence or metastasis but also manages those in an advanced stage by following the wishes of patients and their families as much as possible. However, many patients with esophageal carcinoma develop digestive tract and tracheal problems with progression of the disease, and the palliation of symptoms and continuation of home care often become difficult. In such patients, it is important to secure and maintain the route of hydration and nutrition when oral fluid and food intake becomes difficult, and to control respiratory symptoms for the promotion of home care and palliation of symptoms in the terminal stage. In this report, we present 2 patients managed by palliative care until death while supporting home care by maintaining enteral nutrition using gastrostomy for esophageal narrowing due to cervical lymph node recurrence, and controlling the cough reflex and dyspnea associated with the development of a cervical lymph node-tracheal fistula through morphine hydrochloride administration.","ja":"Our department aggressively performs initial treatment for esophageal carcinoma with multidisciplinary approaches, and not only positively treats patients with recurrence or metastasis but also manages those in an advanced stage by following the wishes of patients and their families as much as possible. However, many patients with esophageal carcinoma develop digestive tract and tracheal problems with progression of the disease, and the palliation of symptoms and continuation of home care often become difficult. In such patients, it is important to secure and maintain the route of hydration and nutrition when oral fluid and food intake becomes difficult, and to control respiratory symptoms for the promotion of home care and palliation of symptoms in the terminal stage. In this report, we present 2 patients managed by palliative care until death while supporting home care by maintaining enteral nutrition using gastrostomy for esophageal narrowing due to cervical lymph node recurrence, and controlling the cough reflex and dyspnea associated with the development of a cervical lymph node-tracheal fistula through morphine hydrochloride administration."},"publication_date":"2013-08-25","publication_name":{"en":"Shikoku Acta Medica","ja":"四国医学雑誌"},"volume":"Vol.69","number":"No.3,4","starting_page":"171","ending_page":"174","languages":["jpn"],"identifiers":{"issn":["0037-3699"]},"published_paper_type":"research_institution"},"priority":"input_data"}
line:52, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30496264"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=274949","label":"url"}],"paper_title":{"en":"【消化器外科看護まるわかり いちからわかる!術前術後ケア・解剖・疾患・治療】(第2章)消化器の解剖・疾患・術前術後ケア入門 <1-1>食道の解剖生理，疾患，検査・治療","ja":"【消化器外科看護まるわかり いちからわかる!術前術後ケア・解剖・疾患・治療】(第2章)消化器の解剖・疾患・術前術後ケア入門 <1-1>食道の解剖生理，疾患，検査・治療"},"authors":{"en":[{"name":"Yamamoto Yota"},{"name":"Tangoku Akira"},{"name":"西野 豪志"},{"name":"Goto Masakazu"},{"name":"Furukita Yoshihito"},{"name":"Takechi Hirokazu"}],"ja":[{"name":"山本 洋太"},{"name":"丹黒 章"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"古北 由仁"},{"name":"武知 浩和"}]},"publication_date":"2013","publication_name":{"en":"Gastroenterological Surgery Nursing","ja":"消化器外科Nursing"},"volume":"Vol.18","number":"No.1","starting_page":"138","ending_page":"150","languages":["jpn"],"identifiers":{"issn":["1341-7819"]},"published_paper_type":"research_institution"},"priority":"input_data"}
line:53, {"insert":{"user_id":"R000010822","type":"published_papers","id":"30496265"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=274946","label":"url"}],"paper_title":{"en":"Ⅰ食道の鏡視下手術 縦隔鏡下食道切除術","ja":"Ⅰ食道の鏡視下手術 縦隔鏡下食道切除術"},"authors":{"en":[{"name":"Tangoku Akira"},{"name":"Yamamoto Yota"},{"name":"Furukita Yoshihito"},{"name":"Takechi Hirokazu"},{"name":"Goto Masakazu"},{"name":"西野 豪志"},{"name":"森本 雅美"}],"ja":[{"name":"丹黒 章"},{"name":"山本 洋太"},{"name":"古北 由仁"},{"name":"武知 浩和"},{"name":"後藤 正和"},{"name":"西野 豪志"},{"name":"森本 雅美"}]},"publication_date":"2013","publication_name":{"en":"Gastroenterological Surgery","ja":"消化器外科"},"volume":"Vol.36","number":"No.5","starting_page":"539","ending_page":"546","languages":["jpn"],"identifiers":{"issn":["0387-2645"]},"published_paper_type":"research_institution"},"priority":"input_data"}
==== end registerFile(/WWW/pub2/data/ERD/person/248930/researchmap/published_papers.jsonl, PebIDI8B7kacV6CWQRPi) ====
==== begin registerFile(/WWW/pub2/data/ERD/person/248930/researchmap/misc.jsonl) ====
line:1, {"insert":{"user_id":"R000010822","type":"misc","id":"30401408"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/22311300","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=267820","label":"url"}],"paper_title":{"en":"Comparison of long-term prognosis of laparoscopy-assisted gastrectomy and conventional open gastrectomy with special reference to D2 lymph node dissection.","ja":"Comparison of long-term prognosis of laparoscopy-assisted gastrectomy and conventional open gastrectomy with special reference to D2 lymph node dissection."},"authors":{"en":[{"name":"Sato Horohiko"},{"name":"Shimada Mitsuo"},{"name":"Kurita Nobuhiro"},{"name":"Iwata Takashi"},{"name":"Nishioka Masanori"},{"name":"Morimoto Shinya"},{"name":"Yoshikawa Kouzou"},{"name":"Miyatani Tomohiko"},{"name":"Goto Masakazu"},{"name":"Kashihara H"},{"name":"Takasu Chie"}],"ja":[{"name":"佐藤 宏彦"},{"name":"島田 光生"},{"name":"栗田 信浩"},{"name":"岩田 貴"},{"name":"西岡 将規"},{"name":"森本 慎也"},{"name":"吉川 幸造"},{"name":"宮谷 知彦"},{"name":"後藤 正和"},{"name":"Kashihara H"},{"name":"髙須 千絵"}]},"description":{"en":"Laparoscopy-assisted gastrectomy (LAG) is becoming widely used for early gastric cancer. However, how the curability and long-term prognosis of LAG and open gastrectomy (OG) for early and advanced gastric cancer compare remains unclear. This study assessed short- and long-term outcomes after LAG with lymph node dissection in early and advanced gastric cancer. A total of 332 patients who underwent LAG or OG for early and advanced gastric cancer from January 2001 through December 2010 were reviewed retrospectively. The mean operating time, estimated mean blood loss, number of dissected lymph nodes, and survival rates were compared between LAG and OG for early and advanced gastric cancer. Overall, 47.6% (158/332) of patients underwent LAG; D1, D1+ lymph node dissection was carried out in 77.2%, with D2 dissection in 22.8%. Only one patient required conversion to OG. Comparing LAG and OG with D1, D1+ lymph node dissection for early gastric cancer (EGC), mean operating time was significantly longer, estimated mean blood loss was significantly smaller, and the average number of retrieved lymph nodes was significantly greater with LAG. The rate of specific postoperative morbidity was 17.2% for LAG patients and 25.0% for OG patients, with no postoperative mortality. Survival and recurrence rates were not significantly different. Comparing LAG and OG with D2 lymph node dissection for advanced gastric cancer (AGC), mean operating time was significantly longer and estimated mean blood loss was significantly smaller with LAG, while the average number of retrieved lymph nodes, specific postoperative morbidity and mortality, and survival and recurrence rates were not significantly different. LAG with D1, D1+ lymph node dissection for EGC is safe and equivalent to open gastrectomy in curability. Moreover, LAG with D2 lymph node dissection for AGC is comparable to OG with D2 lymph node dissection with regard to short- and long-term results.","ja":"Laparoscopy-assisted gastrectomy (LAG) is becoming widely used for early gastric cancer. However, how the curability and long-term prognosis of LAG and open gastrectomy (OG) for early and advanced gastric cancer compare remains unclear. This study assessed short- and long-term outcomes after LAG with lymph node dissection in early and advanced gastric cancer. A total of 332 patients who underwent LAG or OG for early and advanced gastric cancer from January 2001 through December 2010 were reviewed retrospectively. The mean operating time, estimated mean blood loss, number of dissected lymph nodes, and survival rates were compared between LAG and OG for early and advanced gastric cancer. Overall, 47.6% (158/332) of patients underwent LAG; D1, D1+ lymph node dissection was carried out in 77.2%, with D2 dissection in 22.8%. Only one patient required conversion to OG. Comparing LAG and OG with D1, D1+ lymph node dissection for early gastric cancer (EGC), mean operating time was significantly longer, estimated mean blood loss was significantly smaller, and the average number of retrieved lymph nodes was significantly greater with LAG. The rate of specific postoperative morbidity was 17.2% for LAG patients and 25.0% for OG patients, with no postoperative mortality. Survival and recurrence rates were not significantly different. Comparing LAG and OG with D2 lymph node dissection for advanced gastric cancer (AGC), mean operating time was significantly longer and estimated mean blood loss was significantly smaller with LAG, while the average number of retrieved lymph nodes, specific postoperative morbidity and mortality, and survival and recurrence rates were not significantly different. LAG with D1, D1+ lymph node dissection for EGC is safe and equivalent to open gastrectomy in curability. Moreover, LAG with D2 lymph node dissection for AGC is comparable to OG with D2 lymph node dissection with regard to short- and long-term results."},"publication_date":"2012-08","publication_name":{"en":"Surgical Endoscopy","ja":"Surgical Endoscopy"},"volume":"Vol.26","number":"No.8","starting_page":"2240","ending_page":"2246","languages":["eng"],"identifiers":{"doi":["10.1007/s00464-012-2167-x"],"issn":["1432-2218"]},"misc_type":"introduction_scientific_journal"},"priority":"input_data"}
line:2, {"insert":{"user_id":"R000010822","type":"misc","id":"30401409"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/106026","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23037193","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=267854","label":"url"}],"paper_title":{"en":"The safety and usefulness of the single incision, transabdominal pre-peritoneal (TAPP) laparoscopic technique for inguinal hernia.","ja":"The safety and usefulness of the single incision, transabdominal pre-peritoneal (TAPP) laparoscopic technique for inguinal hernia."},"authors":{"en":[{"name":"Sato Horohiko"},{"name":"Shimada Mitsuo"},{"name":"Kurita Nobuhiro"},{"name":"Iwata Takashi"},{"name":"Nishioka Masanori"},{"name":"Morimoto Shinya"},{"name":"Yoshikawa Kouzou"},{"name":"Miyatani Tomohiko"},{"name":"Goto Masakazu"},{"name":"Kashihara H"},{"name":"Takasu Chie"}],"ja":[{"name":"佐藤 宏彦"},{"name":"島田 光生"},{"name":"栗田 信浩"},{"name":"岩田 貴"},{"name":"西岡 将規"},{"name":"森本 慎也"},{"name":"吉川 幸造"},{"name":"宮谷 知彦"},{"name":"後藤 正和"},{"name":"Kashihara H"},{"name":"髙須 千絵"}]},"description":{"en":"The safety and usefulness of the SILS-TAPP (transabdominal pre-peritoneal) procedure remain unclear. The aim of this study was to clarify the safety and usefulness of the SILS-TAPP procedure compared with standard laparoscopic TAPP and TEPP (totally extra-peritoneal pre-peritoneal) procedures. 85 patients underwent laparoscopic inguinal hernia repairs (TEPP, 30 patients; TAPP, 20 patients; SILS-TAPP, 35 patients) from 2007 to 2011. The operative outcomes of the three groups were compared. There was no difference in the patients' characteristics among the three groups. The TEPP Group had a longer operation time. One patient in the SILS-TAPP group had an intraoperative complication. One patient in the TAPP group had a postoperative complication, and one patient had ileus and one had an umbilical hernia in the SILS-TAPP group. The postoperative hospital stay was not significantly different among the three groups. There were no recurrences in the TEPP group, 1 case of recurrence (5.0%) in the TAPP group, and 1 case (2.9%) in the SILS-TAPP group. The present findings show that the SILS-TAPP repair is safe and feasible for the repair of adult inguinal hernia.","ja":"The safety and usefulness of the SILS-TAPP (transabdominal pre-peritoneal) procedure remain unclear. The aim of this study was to clarify the safety and usefulness of the SILS-TAPP procedure compared with standard laparoscopic TAPP and TEPP (totally extra-peritoneal pre-peritoneal) procedures. 85 patients underwent laparoscopic inguinal hernia repairs (TEPP, 30 patients; TAPP, 20 patients; SILS-TAPP, 35 patients) from 2007 to 2011. The operative outcomes of the three groups were compared. There was no difference in the patients' characteristics among the three groups. The TEPP Group had a longer operation time. One patient in the SILS-TAPP group had an intraoperative complication. One patient in the TAPP group had a postoperative complication, and one patient had ileus and one had an umbilical hernia in the SILS-TAPP group. The postoperative hospital stay was not significantly different among the three groups. There were no recurrences in the TEPP group, 1 case of recurrence (5.0%) in the TAPP group, and 1 case (2.9%) in the SILS-TAPP group. The present findings show that the SILS-TAPP repair is safe and feasible for the repair of adult inguinal hernia."},"publication_date":"2012","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"Vol.59","number":"No.3-4","starting_page":"235","ending_page":"240","languages":["eng"],"identifiers":{"doi":["10.2152/jmi.59.235"],"issn":["1349-6867"]},"misc_type":"introduction_scientific_journal"},"priority":"input_data"}
==== end registerFile(/WWW/pub2/data/ERD/person/248930/researchmap/misc.jsonl, P-bIDI8B7kacV6CWQhOo) ====
==== begin registerFile(/WWW/pub2/data/ERD/person/248930/researchmap/books_etc.jsonl) ====
line:1, {"insert":{"user_id":"R000010822","type":"books_etc","id":"30401448"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25981663","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=303668","label":"url"}],"book_title":{"en":"[A case of gastric cancer in which grade 2 treatment effects were obtained with preoperative two-week S-1 administration]. --- 術前2週間のS-1投与によりGrade2の治療効果が得られた進行胃癌の1例","ja":"癌と化学療法 --- 術前2週間のS-1投与によりGrade2の治療効果が得られた進行胃癌の1例"},"authors":{"en":[{"name":"湯浅 康弘"},{"name":"Okitsu Hiroshi"},{"name":"Goto Masakazu"},{"name":"枝川 広志"},{"name":"Ohmori Risa"},{"name":"谷 亮太郎"},{"name":"増田 有理"},{"name":"蔵本 俊輔"},{"name":"松本 大資"},{"name":"富林 敦司"},{"name":"浜田 陽子"},{"name":"Yamashita Ruriko"},{"name":"藤井 義幸"},{"name":"Itou Kouji"}],"ja":[{"name":"湯浅 康弘"},{"name":"沖津 宏"},{"name":"後藤 正和"},{"name":"枝川 広志"},{"name":"大森 理佐"},{"name":"谷 亮太郎"},{"name":"増田 有理"},{"name":"蔵本 俊輔"},{"name":"松本 大資"},{"name":"富林 敦司"},{"name":"浜田 陽子"},{"name":"山下 留理子"},{"name":"藤井 義幸"},{"name":"伊藤 孝司"}]},"publisher":{"en":"株式会社 癌と化学療法社","ja":"株式会社 癌と化学療法社"},"publication_date":"2015-05","languages":["jpn"],"description":{"en":"In our hospital, a clinical trial on the effects of preoperative 2-week S-1 administration for advanced gastric cancer is being conducted. A7 5-year-old man presented to our hospital with a type 2 tumor(poorly differentiated adenocarcinoma)in the pyloric antrum. Subpyloric lymph node enlargement and a c-T2(MP), N1, M0, Stage II A tumor (according to the gastric cancer handling agreement, 14th edition)were diagnosed, and S-1(100mg/day)was subsequently administered for 14 days. On day 15, we performed laparoscopy-assisted distal gastrectomy, with D2 dissection. Analysis of the resected specimen, ie the primary tumor and metastatic lymph nodes, confirmed the effect of the treatment as Grade 2, and revealed a type 2 gastric cancer of 30×20mm in size; this tumor was downstaged to yp-T1b(SM), N1, Stage I B. No adverse events associated with perioperative S-1 were observed, and the postoperative course was good. At the latest follow-up(6 years after treatment), no recurrence was observed.","ja":"In our hospital, a clinical trial on the effects of preoperative 2-week S-1 administration for advanced gastric cancer is being conducted. A7 5-year-old man presented to our hospital with a type 2 tumor(poorly differentiated adenocarcinoma)in the pyloric antrum. Subpyloric lymph node enlargement and a c-T2(MP), N1, M0, Stage II A tumor (according to the gastric cancer handling agreement, 14th edition)were diagnosed, and S-1(100mg/day)was subsequently administered for 14 days. On day 15, we performed laparoscopy-assisted distal gastrectomy, with D2 dissection. Analysis of the resected specimen, ie the primary tumor and metastatic lymph nodes, confirmed the effect of the treatment as Grade 2, and revealed a type 2 gastric cancer of 30×20mm in size; this tumor was downstaged to yp-T1b(SM), N1, Stage I B. No adverse events associated with perioperative S-1 were observed, and the postoperative course was good. At the latest follow-up(6 years after treatment), no recurrence was observed."}},"priority":"input_data"}
==== end registerFile(/WWW/pub2/data/ERD/person/248930/researchmap/books_etc.jsonl, QubIDI8B7kacV6CWQxNZ) ====
==== begin registerFile(/WWW/pub2/data/ERD/person/248930/researchmap/presentations.jsonl) ====
line:1, {"insert":{"user_id":"R000010822","type":"presentations","id":"40234339"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=392414","label":"url"}],"presentation_title":{"en":"The best method of the gastric tube reconstruction after esophagectomy","ja":"The best method of the gastric tube reconstruction after esophagectomy"},"presenters":{"en":[{"name":"Inoue Seiya"},{"name":"Yoshida Takahiro"},{"name":"Goto Masakazu"},{"name":"Fujiwara Satoshi"},{"name":"Tomohiro INUI"},{"name":"Sakamoto Shin-ichi"},{"name":"Miyamoto Naoki"},{"name":"Aoyama Mariko"},{"name":"Toba Hiroaki"},{"name":"Takizawa Hiromitsu"}],"ja":[{"name":"井上 聖也"},{"name":"吉田 卓弘"},{"name":"後藤 正和"},{"name":"藤原 聡史"},{"name":"乾 友浩"},{"name":"坂本 晋一"},{"name":"宮本 直輝"},{"name":"青山 万理子"},{"name":"鳥羽 博明"},{"name":"滝沢 宏光"}]},"event":{"en":"The International Society for Diseases of the Esophagus (VIRTUAL)","ja":"The International Society for Diseases of the Esophagus (VIRTUAL)"},"publication_date":"2022-09-26","languages":["eng"],"is_international_presentation":true},"priority":"input_data"}
line:2, {"insert":{"user_id":"R000010822","type":"presentations","id":"36308348"},"force":{"see_also":[{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85075623295&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=384155","label":"url"}],"presentation_title":{"en":"The sterno-tracheal distance is an important factor of anastomotic leakage of retrosternal gastric tube reconstruction after esophagectomy","ja":"The sterno-tracheal distance is an important factor of anastomotic leakage of retrosternal gastric tube reconstruction after esophagectomy"},"presenters":{"en":[{"name":"Inoue Seiya"},{"name":"Yoshida Takahiro"},{"name":"Nishino Takeshi"},{"name":"Goto Masakazu"},{"name":"Tangoku Akira"}],"ja":[{"name":"井上 聖也"},{"name":"吉田 卓弘"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"丹黒 章"}]},"event":{"en":"The International Society for Diseases of the Esophagus (Virtual)","ja":"The International Society for Diseases of the Esophagus (Virtual)"},"publication_date":"2021-09-27","languages":["eng"],"is_international_presentation":true},"priority":"input_data"}
line:3, {"insert":{"user_id":"R000010822","type":"presentations","id":"39580260"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=388699","label":"url"}],"presentation_title":{"en":"Prognostic impact of CXCR7 and CXCL12 expression in Patients with Esophageal Adenocarcinoma","ja":"Prognostic impact of CXCR7 and CXCL12 expression in Patients with Esophageal Adenocarcinoma"},"presenters":{"en":[{"name":"Goto Masakazu"},{"name":"Yukiko Shibahara"},{"name":"Cristina Baciu"},{"name":"Gail Elizabeth Darling"},{"name":"Mingyao Liu"}],"ja":[{"name":"後藤 正和"},{"name":"Yukiko Shibahara"},{"name":"Cristina Baciu"},{"name":"Gail Elizabeth Darling"},{"name":"Mingyao Liu"}]},"event":{"en":"The International Society for Disease of the Esophagus (Virtual)","ja":"The International Society for Disease of the Esophagus (Virtual)"},"publication_date":"2021-09","languages":["eng"],"is_international_presentation":true},"priority":"input_data"}
line:4, {"insert":{"user_id":"R000010822","type":"presentations","id":"30401449"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=346305","label":"url"}],"presentation_title":{"en":"Oral PresentationTreatment Strategy of Esophageal Cancer from the Expression of HER2 and EGFR","ja":"Oral PresentationTreatment Strategy of Esophageal Cancer from the Expression of HER2 and EGFR"},"presenters":{"en":[{"name":"Inoue Seiya"},{"name":"Goto Masakazu"},{"name":"Nishino Takeshi"},{"name":"Yoshida Takahiro"},{"name":"Tangoku Akira"}],"ja":[{"name":"井上 聖也"},{"name":"後藤 正和"},{"name":"西野 豪志"},{"name":"吉田 卓弘"},{"name":"丹黒 章"}]},"event":{"en":"International Society for Diseases of the Esophagus","ja":"International Society for Diseases of the Esophagus"},"publication_date":"2018-09-16","languages":["eng"],"is_international_presentation":true},"priority":"input_data"}
line:5, {"insert":{"user_id":"R000010822","type":"presentations","id":"30401450"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=346304","label":"url"}],"presentation_title":{"en":"Oral PresentationDiagnostic Utility of Endobronchial Ultrasonography for the Tracheobronchial Invasion of Esophageal Cancer","ja":"Oral PresentationDiagnostic Utility of Endobronchial Ultrasonography for the Tracheobronchial Invasion of Esophageal Cancer"},"presenters":{"en":[{"name":"Nishino Takeshi"},{"name":"Toba Hiroaki"},{"name":"Yoshida Takahiro"},{"name":"Inoue Seiya"},{"name":"Goto Masakazu"},{"name":"Tangoku Akira"}],"ja":[{"name":"西野 豪志"},{"name":"鳥羽 博明"},{"name":"吉田 卓弘"},{"name":"井上 聖也"},{"name":"後藤 正和"},{"name":"丹黒 章"}]},"event":{"en":"International Society for Diseases of the Esophagus","ja":"International Society for Diseases of the Esophagus"},"publication_date":"2018-09-16","languages":["eng"],"is_international_presentation":true},"priority":"input_data"}
line:6, {"insert":{"user_id":"R000010822","type":"presentations","id":"30401451"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/29892933","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85038619573&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=346303","label":"url"}],"presentation_title":{"en":"The Effects of the Herbal Medicine Daikenchuto(Tj-100) after Esophageal Cancer Resection, Open-Label, Randomized Controlled Trial","ja":"The Effects of the Herbal Medicine Daikenchuto(Tj-100) after Esophageal Cancer Resection, Open-Label, Randomized Controlled Trial"},"presenters":{"en":[{"name":"Tangoku Akira"},{"name":"Nishino Takeshi"},{"name":"Inoue Seiya"},{"name":"Goto Masakazu"},{"name":"Yoshida Takahiro"}],"ja":[{"name":"丹黒 章"},{"name":"西野 豪志"},{"name":"井上 聖也"},{"name":"後藤 正和"},{"name":"吉田 卓弘"}]},"event":{"en":"Esophagus","ja":"Esophagus"},"publication_date":"2018-09-16","languages":["eng"],"description":{"en":"Daikenchuto (TJ-100), a traditional Japanese herbal medicine, is widely used in Japan. Its effects on gastrointestinal motility and microcirculation and its anti-inflammatory effect are known. The purpose of this prospective randomized controlled trial was to investigate the effect of TJ-100 after esophagectomy in esophageal cancer patients. Forty patients for whom subtotal esophageal resection for esophageal cancer was planned at our institute from March 2011 to August 2013 were enrolled and divided into two groups at the point of determination of the operation schedule after informed consent was obtained: a TJ-100 (15 g/day)-treated group (n = 20) and a control group (n = 20). The primary efficacy end-points were maintenance of the nutrition condition and the recovery of gastrointestinal function. The secondary efficacy end-points were the serum C-reactive protein (CRP) level and adrenomedullin level during the postoperative course, the incidence of postoperative complications, and the length of hospital stay after surgery. We examined 39 patients because one patient in the TJ-100 group was judged as having unresectable cancer after surgery. The mean age of the TJ-100 group patients was significantly older than that of the control group patients.The rate of body weight decrease at postoperative day 21 was significantly suppressed in the TJ-100 group (3.6% vs. the control group: 7.0%, p = 0.014), but the serum albumin level was not significantly different between the groups. The recovery of gastrointestinal function regarding flatus, defecation, and oral intake showed no significant between-group differences, but postoperative bowel symptoms tended to be rare in the TJ-100 group. There was no significant between-group difference in the length of hospital stay after surgery. The serum CRP level at postoperative day 3 was 4.9 mg/dl in the TJ-100 group and 6.9 mg/dl in the control group, showing a tendency of a suppressed serum CRP level in the TJ-100 group (p = 0.126). The rate of increase in adrenomedullin tended to be high postoperatively, but there was no significant difference between the two groups. TJ-100 treatment after esophageal cancer resection has the effects of prompting the recovery of gastrointestinal motility and minimizing body weight loss, and it might suppress the excess inflammatory reaction related to surgery.","ja":"Daikenchuto (TJ-100), a traditional Japanese herbal medicine, is widely used in Japan. Its effects on gastrointestinal motility and microcirculation and its anti-inflammatory effect are known. The purpose of this prospective randomized controlled trial was to investigate the effect of TJ-100 after esophagectomy in esophageal cancer patients. Forty patients for whom subtotal esophageal resection for esophageal cancer was planned at our institute from March 2011 to August 2013 were enrolled and divided into two groups at the point of determination of the operation schedule after informed consent was obtained: a TJ-100 (15 g/day)-treated group (n = 20) and a control group (n = 20). The primary efficacy end-points were maintenance of the nutrition condition and the recovery of gastrointestinal function. The secondary efficacy end-points were the serum C-reactive protein (CRP) level and adrenomedullin level during the postoperative course, the incidence of postoperative complications, and the length of hospital stay after surgery. We examined 39 patients because one patient in the TJ-100 group was judged as having unresectable cancer after surgery. The mean age of the TJ-100 group patients was significantly older than that of the control group patients.The rate of body weight decrease at postoperative day 21 was significantly suppressed in the TJ-100 group (3.6% vs. the control group: 7.0%, p = 0.014), but the serum albumin level was not significantly different between the groups. The recovery of gastrointestinal function regarding flatus, defecation, and oral intake showed no significant between-group differences, but postoperative bowel symptoms tended to be rare in the TJ-100 group. There was no significant between-group difference in the length of hospital stay after surgery. The serum CRP level at postoperative day 3 was 4.9 mg/dl in the TJ-100 group and 6.9 mg/dl in the control group, showing a tendency of a suppressed serum CRP level in the TJ-100 group (p = 0.126). The rate of increase in adrenomedullin tended to be high postoperatively, but there was no significant difference between the two groups. TJ-100 treatment after esophageal cancer resection has the effects of prompting the recovery of gastrointestinal motility and minimizing body weight loss, and it might suppress the excess inflammatory reaction related to surgery."},"is_international_presentation":true},"priority":"input_data"}
line:7, {"insert":{"user_id":"R000010822","type":"presentations","id":"30401452"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=286189","label":"url"}],"presentation_title":{"en":"New Minimal Invasive Strategy for Superficial Esophageal Cancer","ja":"New Minimal Invasive Strategy for Superficial Esophageal Cancer"},"presenters":{"en":[{"name":"Furukita Yoshihito"},{"name":"Tangoku Akira"},{"name":"藤原 聡史"},{"name":"井上 聖也"},{"name":"西野 豪志"},{"name":"Goto Masakazu"},{"name":"湊 拓也"},{"name":"Yamamoto Yota"},{"name":"湯浅 康弘"},{"name":"山井 礼道"},{"name":"Takechi Hirokazu"},{"name":"Yoshida Takahiro"},{"name":"Seike Jun-ichi"}],"ja":[{"name":"古北 由仁"},{"name":"丹黒 章"},{"name":"藤原 聡史"},{"name":"井上 聖也"},{"name":"西野 豪志"},{"name":"後藤 正和"},{"name":"湊 拓也"},{"name":"山本 洋太"},{"name":"湯浅 康弘"},{"name":"山井 礼道"},{"name":"武知 浩和"},{"name":"吉田 卓弘"},{"name":"清家 純一"}]},"event":{"en":"26th International Conference of the Society for Medical Innovation and Technology","ja":"26th International Conference of the Society for Medical Innovation and Technology"},"publication_date":"2014-09-18","languages":["eng"],"is_international_presentation":true},"priority":"input_data"}
line:8, {"insert":{"user_id":"R000010822","type":"presentations","id":"30401453"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=251011","label":"url"}],"presentation_title":{"en":"Simultaneous laparoscopic resection of primary colorectal cancer and metastatic liver tumor.","ja":"Simultaneous laparoscopic resection of primary colorectal cancer and metastatic liver tumor."},"presenters":{"en":[{"name":"Takasu Chie"},{"name":"Shimada Mitsuo"},{"name":"Kurita Nobuhiro"},{"name":"Iwata Takashi"},{"name":"Sato Horohiko"},{"name":"Nishioka Masanori"},{"name":"Morimoto Shinya"},{"name":"Yoshikawa Kouzou"},{"name":"Miyatani Tomohiko"},{"name":"Goto Masakazu"},{"name":"柏原 秀也"},{"name":"Utsunomiya Toru"}],"ja":[{"name":"髙須 千絵"},{"name":"島田 光生"},{"name":"栗田 信浩"},{"name":"岩田 貴"},{"name":"佐藤 宏彦"},{"name":"西岡 将規"},{"name":"森本 慎也"},{"name":"吉川 幸造"},{"name":"宮谷 知彦"},{"name":"後藤 正和"},{"name":"柏原 秀也"},{"name":"宇都宮 徹"}]},"event":{"en":"Society of American Gastrointestinal Endoscopic Surgeons (SAGES2012)","ja":"Society of American Gastrointestinal Endoscopic Surgeons (SAGES2012)"},"publication_date":"2012-03-07","languages":["eng"],"location":{"en":"San Diego","ja":"San Diego"},"is_international_presentation":true},"priority":"input_data"}
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====== BulkResult(R000010822, RObIDI8B7kacV6CWRRNS) : End ======