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Tokushima University > Research Clusters > Research Clusters (Registered) > 1803001 要介護リスクを高める骨粗鬆症・関節リウマチにおける骨代謝制御機構とその破綻のエピゲノム解析 >
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Subject of Study

Book / Paper

Book:

1. Eiji Tanaka, Hirofumi Tenshin, Hiroki Mori and Keiichiro Watanabe :
B-maxスクリュー Type-TKを用いた成人開咬の治療戦略,
クインテッセンス出版株式会社, Tokyo, 2018.

Academic Paper (Judged Full Paper):

1. Aki Ichihara, Shinya Horiuchi, Naoko Ogasawara, Hiroki Mori, Ryota Amachi, Keiichiro Watanabe, Nao Kinouchi, Akihiro Yasue and Eiji Tanaka :
徳島大学病院矯正歯科における口唇裂・口蓋裂患者の永久歯の歯数異常に関する調査,
The Journal of Chu-Shikoku Orthodontic Society, Vol.30, No.1, 51-58, 2018.
2. Islamy Rahma Hutami, Takashi Izawa, Akiko Mino, Takehiro Shinohara, Hiroki Mori, Akihiko Iwasa and Eiji Tanaka :
Fas/S1P1 crosstalk via NF-B activation in osteoclasts controls subchondral bone remodeling in murine TMJ arthritis,
Biochemical and Biophysical Research Communications, Vol.490, No.4, 1274-1281, 2017.
(Tokushima University Institutional Repository: 113368,   DOI: 10.1016/j.bbrc.2017.07.006,   PubMed: 28687489)
3. Takashi Izawa, Islamy Rahma Hutami, Hiroki Mori and Eiji Tanaka :
Role of Smad3 and S1P Signaling in Mandibular Condylar Cartilage Homeostasis,
Journal of Bone Research, Vol.5, No.2, 178, 2017.
(DOI: 10.4172/2572-4916.1000178)
4. Akiko Mino, Takashi Izawa, Takehiro Shinohara, Hiroki Mori, Akihiro Yasue, Shuhei Tomita and Eiji Tanaka :
Roles of hypoxia inducible factor-1α in the temporomandibular joint.,
Archives of Oral Biology, Vol.73, 274-281, 2017.
(Tokushima University Institutional Repository: 110094,   DOI: 10.1016/j.archoralbio.2016.10.028,   PubMed: 27816790)
5. Takashi Izawa, Rieko Arakaki, Hiroki Mori, Takaaki Tsunematsu, Yasusei Kudo, Eiji Tanaka and Naozumi Ishimaru :
The nuclear receptor AhR controls bone homeostasis by regulating osteoclast differentiation via the RANK/c-Fos signaling axis.,
The Journal of Immunology, Vol.197, No.12, 4639-4650, 2016.
(DOI: 10.4049/jimmunol.1600822,   PubMed: 27849171)
6. Takehiro Shinohara, Takashi Izawa, Akiko Mino, Hiroki Mori, Akihiko Iwasa, Toshihiro Inubushi, Yu Yamaguchi and Eiji Tanaka :
Hyaluronan metabolism in overloaded temporomandibular joint,
Journal of Oral Rehabilitation, Vol.43, No.12, 921-928, 2016.
(Tokushima University Institutional Repository: 110120,   DOI: 10.1111/joor.12443,   PubMed: 27627706,   Elsevier: Scopus)
7. Takashi Izawa, Hiroki Mori, Takehiro Shinohara, Akiko Mino, Islamy Rahma Hutami, Akihiko Iwasa and Eiji Tanaka :
Correction: Rebamipide Attenuates Mandibular Condylar Degeneration in a Murine Model of TMJ-OA by Mediating a Chondroprotective Effect and by Downregulating RANKL-Mediated Osteoclastogenesis.,
PLoS ONE, Vol.11, No.8, e0162032, 2016.
(DOI: 10.1371/journal.pone.0162032,   PubMed: 27560140)
8. Takashi Izawa, Hiroki Mori, Takehiro Shinohara, Akiko Mino, Islamy Rahma Hutami, Akihiko Iwasa and Eiji Tanaka :
Rebamipide attenuates mandibular condylar degeneration in a murine model of TMJ-OA by mediating a chondroprotective effect and by downregulating RANKL-mediated osteoclastogenesis,
PLoS ONE, Vol.11, No.4, e0154107, 2016.
(Tokushima University Institutional Repository: 112307,   DOI: 10.1371/journal.pone.0154107,   PubMed: 27123995)
9. Hiroki Mori, Takashi Izawa and Eiji Tanaka :
Smad3 deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P)/S1P3 signaling axis.,
The American Journal of Pathology, Vol.185, No.10, 2742-2756, 2015.
(DOI: 10.1016/j.ajpath.2015.06.015,   PubMed: 26272361)
10. Takehiro Shinohara, Keiichiro Watanabe, Hiroki Mori, Takashi Izawa, Shinya Horiuchi, Shingo Kuroda, Kotaro Tanimoto and Eiji Tanaka :
顎関節内障を有する骨格性下顎前突症に対する矯正歯科治療の一治験例,
The Journal of Chu-Shikoku Orthodontic Society, Vol.27, No.1, 39-48, 2015.

Proceeding of International Conference:

1. Susumu Abe, Hiroki Mori, Eiji Tanaka, Tachibana Naoko, Murakami Ayu, Kazuo Okura, Yoshitaka Suzuki, Toshinori Okawa and Fumiaki Kawano :
Craniofacial morphology in OSA patients treated by oral appliance with and without sufficient effects,
2019 World Sleep Congress, Sep. 2019.
2. Tsendsuren Khurel-Ochir, Takashi Izawa, Hiroki Mori, Akihiko Iwasa, Islamy Rahma Hutami and Eiji Tanaka :
The role of p21 on the development of TMJ-OA,
6th Meeting of Mongolian Association of Orthdontists,, Ulaanbaatar, Mongolia., Sep. 2018.
3. Islamy Rahma Hutami, Hiroki Mori, Tsendsuren Khurel-Ochir, Akiko Mino, Akihiko Iwasa, Eiji Tanaka and Takashi Izawa :
HIF-1alpha regulates the palatal wound healing through M1/M2 macrophage reprogramming,
96th General Session & Exhibition of the IADR, 214, London, Jul. 2018.
4. Islamy Rahma Hutami, Takashi Izawa, Hiroki Mori, Takehiro Shinohara, Akiko Mino, Akihiko Iwasa and Eiji Tanaka :
Fas/S1P1 signaling controls temporomandibular joint subchondral bone remodeling in autoimmune-arthritis.,
95th General Session & Exhibition of the IADR program book, 243, San Francisco, Mar. 2017.
5. Minami Sato, Mutsumi Fujita, Akihiko Iwasa, Hiroki Mori, Akiko Mino, Natsuko Hichijo, Shinya Horiuchi and Eiji Tanaka :
Effect of Low-intensity Pulsed Ultrasound on ATDC5 Cells Under Inflammation,
95th General Session & Exhibition of the IADR program book, San Francisco, Mar. 2017.
6. Hiroki Mori, Takashi Izawa, Takehiro Shinohara, Akiko Mino, Minami Sato, Natsuko Hichijo, Akihiko Iwasa, Islamy Rahma Hutami and Eiji Tanaka :
Effect of Rebamipide administration on TMJ-OA model mouse.,
95th General Session & Exhibition of the IADR program book, 207, San Francisco, Mar. 2017.
7. Hiroki Mori, Takashi Izawa and Eiji Tanaka :
Role of Rho-GTP/S1P/Smad3 Signaling on the Pathogenesis of TMJ-OA.,
International Association for Dental Research General Session, Seoul, Jun. 2016.
8. Hiroki Mori, Takashi Izawa and Eiji Tanaka :
Smad3 deficiency leads to mandibular condyle degeneration via the Sphingosine 1-phosphate (S1P)/ S1P3 signaling axis,
ASBMR 2015 Annual Meeting, 143, Seattle, Oct. 2015.
9. Hiroki Mori, Takashi Izawa and Eiji Tanaka :
Role of Smad3 and lysophospholipid receptor S1P3 signaling in the pathogenesis of TMJ-OA,
The 3rd ASEAN Plus and Tokushima Joint International Conference, Makassar, Indonesia., Dec. 2014.

Proceeding of Domestic Conference:

1. Tsendsuren Khurel-Ochir, Takashi Izawa, Takuma Sakamaki, Hiroki Mori and Eiji Tanaka :
Immunoregulatory role of p21 on the development of osteoarthritis in the temporomandibular joint,
第78回日本矯正歯科学会学術大会: 日本矯正歯科学会大会プログラム・抄録集 78回 Page288.(2019), 288, Nov. 2019.
2. Takuma Sakamaki, Akihiko Iwasa, Hiroki Mori, Naoko Ogasawara, Kotaro Tanimoto, MOHANNAD ASHTAR, YAO LIU, Masaki Sawada, Tatsuya Nakamura, Shinya Horiuchi and Eiji Tanaka :
矯正治療中に生じた下顎中切歯の歯肉退縮に対して結合組織移植術を行った歯性上顎前突症例―長期保定症例,
第62回中・四国矯正歯科学会大会, Vol.31, No.1, Jul. 2019.
3. 森 仁志, Hiroki Mori, 塩屋園 玲子, Keiichiro Watanabe, Shinya Horiuchi, 菅野 貴浩 and Eiji Tanaka :
閉塞性睡眠時無呼吸症候群を伴うPierre Robin Sequenceに対し下顎骨前方移動術を行った1例,
第62回中・四国矯正歯科学会大会, Vol.31, No.1, Jul. 2019.
4. Islamy Rahma Hutami, Hiroki Mori, Tsendsuren Khurel-Ochir, Akiko Mino, Akihiko Iwasa, Eiji Tanaka and Takashi Izawa :
HIF1α modulates the palatal wound healing via M1/M2 marcophage reprogramming.,
第66回国際歯科研究学会日本部会総会・学術大会(JADR2018), Nov. 2018.
5. Tsendsuren Khurel-Ochir, Takashi Izawa, Hiroki Mori, Akihiko Iwasa, Islamy Rahma Hutami and Eiji Tanaka :
The role of p21 on the development of TMJ-OA,
The 77th Annual Meeting of the Japanese Orthodontic Society, Vol.77, 79, Nov. 2018.
6. Mutsumi Fujita, 重田 南, Hiroki Mori, Akihiko Iwasa, Nobuhiko Kawai and Eiji Tanaka :
変形性顎関節症モデルラット下顎頭及び炎症状態下軟骨細胞に対する低出力パルス超音波照射の影響,
第77回日本矯正歯科学会学術大会: 日本矯正歯科学会大会プログラム・抄録集 77回 Page320.(2018.10), 320, Oct. 2018.
7. Naoko Ogasawara, Hiroki Mori, Akihito Yamamoto and Eiji Tanaka :
変形性顎関節症に対するヒト脱落乳歯歯髄幹細胞由来無血清馴化培地の治療効果の検討,
第77回日本矯正歯科学会学術大会: 日本矯正歯科学会大会プログラム・抄録集 77回 Page245.(2018.10), 245, Oct. 2018.
8. Yoshiro Abe, Keisuke Kashiwagi, Soushi Ishida, Kazuhide Mineda, Yutaro Yamashita, Sho Yoshimoto, Hiroki Mori, Eiji Tanaka and Ichiro Hashimoto :
乳児黒色性神経外胚葉性腫瘍の下顎骨亜全摘症例に対し二期的な遊離肩甲骨移植で良好な咬合を獲得した1例,
第36回 日本頭蓋顎顔面外科学会学術集会, Oct. 2018.
9. 森 仁志, Hiroki Mori, 塩屋園 玲子, Keiichiro Watanabe, Shinya Horiuchi and Eiji Tanaka :
上顎中切歯の翼状捻転を伴う叢生症例,
第61回中・四国矯正歯科学会大会, Vol.30, No.1, 77-78, Jul. 2018.
10. Islamy Rahma Hutami, Takashi Izawa, Hiroki Mori, Akiko Oka, Tsendsuren Khurel-Ochir, Akihiko Iwasa and Eiji Tanaka :
低酸素応答遺伝子 HIF-1alpha は M1/M2 マクロファージの リプログラミングを介して口蓋創傷治癒を制御する.,
第42回日本口蓋裂学会総会・学術集会 抄録号, Vol.43, No.2, 182, May 2018.
11. Kotaro Tanimoto, Hiroki Mori, Takashi Izawa, Nobuhiko Kawai, Akihiro Yasue and Eiji Tanaka :
徳島大学病院における過去 10 年間の口唇裂・口蓋裂患者に関する実態調査,
第42回日本口蓋裂学会総会・学術集会 抄録号, Vol.43, No.2, 178, May 2018.
12. Islamy Rahma Hutami, Takashi Izawa, Akihiko Iwasa, Akiko Mino, Tsendsuren Khurelochir, Hiroki Mori and Eiji Tanaka :
Role of hypoxia inducible factor-1 alpha in the palatal wound healing,
The 76th Annual Meeting of the Japanese Orthodontic Society Academic Exhibits (AE-012), 309, Oct. 2017.
13. Akihiko Iwasa, Takashi Izawa, Hiroki Mori, Akiko Oka, Mutsumi Fujita, Nobuhiko Kawai, Shinya Horiuchi and Eiji Tanaka :
歯科矯正患者における進行性下顎頭吸収の発現頻度とその危険因子の検索,
第30回日本顎関節学会総会・学術大会, Jul. 2017.
14. Mutsumi Fujita, 重田 南, Akihiko Iwasa, Hiroki Mori, Nobuhiko Kawai, Takashi Izawa, Shinya Horiuchi and Eiji Tanaka :
変形性顎関節症モデルラット下顎頭及び炎症状態下軟骨細胞に対する低出力パルス超音波による影響.,
Journal of the Japanese Society for the Temporomandibular Joint, Jul. 2017.
15. 森 仁志, Hiroki Mori, 塩屋園 玲子, Keiichiro Watanabe, Shinya Horiuchi and Eiji Tanaka :
ペンデュラムアプライアンスを使用して上顎第一大臼歯を遠心移動した3症例,
第60回中・四国矯正歯科学会大会, Jul. 2017.
16. Islamy Rahma Hutami, Takashi Izawa, Hiroki Mori, Akihiko Iwasa, Takehiro Shinohara, Akiko Mino and Eiji Tanaka :
The role of osteoclast in the spontaneously developed temporomandibular joint arthritis of the MRL/lpr mice,
The 75th Annual Meeting of the Japanese Orthodontic Society, 321, Nov. 2016.
17. Akiko Mino, Takashi Izawa, Islamy Rahma Hutami, Takehiro Shinohara, Hiroki Mori and Eiji Tanaka :
変形性顎関節症における低酸素誘導因子HIF-1αの機能解析,
日本矯正歯科学会大会プログラム・抄録集. 第75回大会, Nov. 2016.
18. 森 仁志, Hiroki Mori, Takehiro Shinohara, Ryota Amachi, 塩屋園 玲子, Keiichiro Watanabe, Shinya Horiuchi, 菅野 貴浩 and Eiji Tanaka :
比較的大きな顎裂を有する口唇口蓋裂患者に対する骨トランスポート骨延長法の応用,
日本矯正歯科学会大会プログラム・抄録集., 263., Nov. 2016.
19. Akihiko Iwasa, Hiroki Mori, Takashi Izawa, Takehiro Shinohara, Akiko Mino, Minami Sato, Shinya Horiuchi and Eiji Tanaka :
Satistical survey of temporomandibular disorders in patients with malocclusion,
The 29th Annual Meeting of The Japanese Society for Temporomandibular Joint, Vol.28, No.Supplement, 145, Jul. 2016.
20. Takehiro Shinohara, Takashi Izawa, Akihiko Iwasa, Hiroki Mori, Akiko Mino, Toshihiro Inubushi and Eiji Tanaka :
Role of hyaluronan metabolism in experimentally induced temporomandibular joint osteoarthritis,
The 29th Annual Meeting of the Japanese Society for Temporomandibular Joint, Vol.28, No.Supplement, 123, Jul. 2016.
21. Akiko Mino, Takashi Izawa, Takehiro Shinohara, Hiroki Mori and Eiji Tanaka :
Functional analysis of HIF-1alpha in osteoarthritic TMJ using HIF-1alpha deficient mice,
The 29th Annual Meeting of the Japanese Society for Temporomandibular Joint, Vol.28, No.Supplement, 115, Jul. 2016.
22. Hiroko Sato, Takashi Izawa, Hiroki Mori, Akihiko Iwasa, Nao Kinouchi, Shinya Horiuchi and Eiji Tanaka :
A case of Apert syndrome treated with two-jaw surgery after Le Fort III distraction osteogenesis,
第59回中・四国矯正歯科学会大会 学術口演, Jul. 2016.
23. Minami Sato, Akihiko Iwasa, Hiroki Mori, Shinya Horiuchi and Eiji Tanaka :
関節滑膜細胞に対する低出力超音波照射によって生じる抗炎症シグナル伝達経路の解明,
日本顎関節学会雑誌., 124., Jun. 2016.
24. Akiko Mino, Takashi Izawa, Takehiro Shinohara, Hiroki Mori, Hiroyo Mori, Akihiko Iwasa and Eiji Tanaka :
マウス下顎頭軟骨の形成,維持におけるHIF-1αの機能解析,
第74回日本矯正歯科学会大会プログラム・抄録集, 204, Nov. 2015.
25. Hiroki Mori, Takashi Izawa, Akiko Mino, Akihiko Iwasa, Ryoko Uchida and Eiji Tanaka :
S1P/Smad3シグナルクロストークを介した変形性顎関節症の病態メカニズムの解明,
第74回日本矯正歯科学会大会プログラム・抄録集, 194, Nov. 2015.
26. Takashi Izawa, Hiroki Mori, Takehiro Shinohara, Akiko Mino, Chieko Shiota, Toshihiro Inubushi, Akihiko Iwasa and Eiji Tanaka :
変形性顎関節症モデルマウスにおけるレパミピドの治療効果の検討,
第74回日本矯正歯科学会大会プログラム・抄録集, 193, Nov. 2015.
27. Takehiro Shinohara, Takashi Izawa, Akiko Mino, Hiroki Mori, Natsuko Hichijo, Toshihiro Inubushi and Eiji Tanaka :
実験的な変形性顎関節症モデルマウス下顎頭におけるヒアルロン酸の役割,
第74回日本矯正歯科学会大会プログラム・抄録集, 190, Nov. 2015.
28. Eiji Tanaka, Takashi Izawa, Hiroki Mori, Nobuhiko Kawai, Akihiro Yasue and Shinya Horiuchi :
片側性顎関節円板前方転位が健側顎関節に及ぼす影響に関する生体力学的解析,
第23回顎顔面バイオメカニクス学会プログラム, 193, Nov. 2015.
29. Hirofumi Tenshin, Keiichiro Watanabe, Natsuko Hichijo, Akiko Mino, Hiroki Mori, MANSJUR KARIMA QURNIA, Akihiro Yasue, Shingo Kuroda and Eiji Tanaka :
歯科矯正用アンカースクリューを用いた下顎臼歯遠心移動量および移動様式の治療前予測に関する検討,
第58回中·四国矯正歯科学会大会, 14, Jul. 2015.
30. Hiroki Mori, Takashi Izawa and Eiji Tanaka :
Role of S1P/Smad3 signaling in the pathogenesis of TMJ-OA,
Journal of the Japanese Society for the Temporomandibular Joint, Vol.27, No.Supplement, 149, Jul. 2015.
31. Takashi Izawa, Hiroki Mori, Takehiro Shinohara, Akihiko Iwasa and Eiji Tanaka :
Effect of rebamipide administration on TMJ-OA model mouse,
Journal of the Japanese Society for the Temporomandibular Joint, Vol.27, No.Supplement, 148, Jul. 2015.
32. Hiroki Mori, Takashi Izawa and Eiji Tanaka :
変形性顎関節症の病態形成におけるS1P/Smad3シグナルの役割,
第73回日本矯正歯科学会大会プログラム・抄録集, 217, Oct. 2014.
33. Hiroki Mori, Takashi Izawa and Eiji Tanaka :
Role of Smad3 signaling in pathogenesis of TMJ-OA,
Journal of the Japanese Society for the Temporomandibular Joint, Vol.26, No.Supplement, 107, Jul. 2014.
34. Takehiro Shinohara, Keiichiro Watanabe, Hiroki Mori, Takashi Izawa, Shinya Horiuchi, Shingo Kuroda and Eiji Tanaka :
顎関節内障を有する骨格性下顎前突症に対する矯正歯科治療の一治験例,
第57回中·四国矯正歯科学会大会, 21, Jul. 2014.
35. Keiichiro Watanabe, Shingo Kuroda, Hiroki Mori and Eiji Tanaka :
歯科矯正用アンカースクリューを用いて治療した成長期の骨格性II級前歯部開咬症例,
第72回日本矯正歯科学会大会プログラム・抄録集, Oct. 2013.
36. Takashi Izawa, Hiroki Mori, Shinya Horiuchi, Nobuhiko Kawai and Eiji Tanaka :
Dynamic viscoelastic properties of condylar and temporal cartilages in the porcine temporomandibular joint,
Journal of the Japanese Society for the Temporomandibular Joint, Vol.25, No.Supplement, 84, Jul. 2013.
37. Hiroki Mori, Keiichiro Watanabe, Ryoko Uchida, Takashi Izawa, Shingo Kuroda, 森 仁志 and Eiji Tanaka :
圧迫骨短縮術を施術した,エナメル質形成不全を伴う骨格性開咬の一治療例,
第56回中·四国矯正歯科学会大会, Jul. 2013.

Et cetera, Workshop:

1. Islamy Rahma Hutami, Takashi Izawa, Hiroki Mori, Akihiko Iwasa, Takehiro Shinohara, Akiko Mino and Eiji Tanaka :
Fas/S1P system controls subchondral bone remodeling of the temporomandibular joint in autoimmune arthritic mice.,
2016 Tokushima Bioscience Retreat, Sep. 2016.
2. Takashi Izawa, Hiroki Mori, Takehiro Shinohara, Akiko Mino-Oka, Islamy Rahma Hutami, Akihiko Iwasa and Eiji Tanaka :
Correction: Rebamipide Attenuates Mandibular Condylar Degeneration in a Murine Model of TMJ-OA by Mediating a Chondroprotective Effect and by Downregulating RANKL-Mediated Osteoclastogenesis.,
PLoS ONE, Vol.11, No.8, e0162032, Aug. 2016.
(DOI: 10.1371/journal.pone.0162032,   PubMed: 27560140)
3. Takashi Izawa, Hiroki Mori, Takehiro Shinohara, Akiko Mino, Islamy Rahma Hutami, Akihiko Iwasa and Eiji Tanaka :
Rebamipide attenuates mandibular condylar degeneration in a murine model of TMJ-OA by mediating a chondroprotective effect and by downregulating RANKL-mediated osteoclastogenesis,
13th Meeting of Bone Biology Forum, Aug. 2016.
4. Takashi Izawa, Hiroki Mori and Eiji Tanaka :
S1P/Smad3シグナルを介した顎関節における変形性関節症の病態解明,
第7回 骨バイオサイエンス研究会, Jun. 2016.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • p21細胞周期チェックポイントを標的とした口蓋粘膜創傷治癒機構の解明 (Project/Area Number: 18K17260 )
  • 顎顔面領域骨代謝性疾患におけるエピゲノム制御による新規骨リモデリング機構の解明 (Project/Area Number: 18H03011 )
  • Challenge to control the palatal scar formation and to analyze the regulatory mechanizm of metabolic reprogramming via hypoxia inducible genes (Project/Area Number: 17K19758 )
  • The mechanism of TMJ-OA pathogenesis in HIF-1a gene deficient mice (Project/Area Number: 16H07019 )
  • Search by Researcher Number (90779985)