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en: Enantioselective Synthesis of Planar-Chiral Transition-Metal Complexes by Homogeneous Olefi n-Metathesis Reactions and Their Application in Asymmetric Catalysis

ja: 均一系オレフィン・メタセシス反応による面不斉遷移金属錯体のエナンチオ選択的合成法の開発と不斉触媒反応への応用

en: Planar-chiral transition-metal complexes are important chiral scaffolds in organic and organometallic chemistry and have been utilized as chiral ligands, chiral catalysts, or chiral building blocks. In spite of the usefulness of the planar-chiral species in asymmetric synthesis, enantiomerically enriched forms of these compounds are primarily obtained by rather classical methods. Indeed, examples of catalytic enantio-control of planar chirality in transition-metal complexes have been extremely rare, and this has been still a developing area in this fi eld. In this account, recent results from our research group on the catalytic asymmetric synthesis of various planar-chiral transition-metal complexes are outlined. The Mo-catalyzed asymmetric ring-closing metathesis has been found to be a powerful method to control the planar chirality in various transition-metal complexes such as ferrocenes, ruthenocenes, (ϖ-arene)chromium complexes, cymantrene derivatives, etc. Application of the highly enantiomerically enriched planar-chiral complexes in asymmetric synthesis has been also demonstrated.

en: Bulletin of Japan Society of Coordination Chemistry


en: モリブデン触媒不斉オレフィン・メタセシスによる面不斉遷移金属錯体の触媒的不斉合成

en: Organometallic News

ja: Organometallic News


en: Cross-Coupling Reactions Other Than Suzuki-Miyaura Coupling

en: Science of Synthesis, Reference Library

ja: Science of Synthesis, Reference Library


en: メタセシス反応による面不斉遷移金属錯体の触媒的不斉合成

ja: メタセシス反応による面不斉遷移金属錯体の触媒的不斉合成

en: ファインケミカル

ja: ファインケミカル


en: Catalytic Asymmetric Synthesis of Planar-Chiral Transition-Metal Complexes

en: Tetrahedron Letters

ja: Tetrahedron Letters


ja: 面不斉遷移金属錯体の触媒的不斉合成

en: Although ``central chirality'' based on stereogenic carbon atoms is arguably the most common chiral element in organic chemistry, chiral molecules devoid of stereogenic centers play important roles in stereoselective organic transformations. Among these chiral compounds with ``non-centrochirality'', planar-chiral transition-metal complexes have been utilized as chiral ligands, chiral catalysts, or chiral building blocks in asymmetric synthesis. However, enantiomerically enriched forms of these compounds are primarily obtained by rather classical methods. Examples of catalytic enantioselective induction of planar-chirality in transition-metal species have been extremely rare and still a developing area in this field. In this review article, catalytic asymmetric synthesis of various ``planar-chiral transition-metal complexes'' are surveyed in a comprehensive manner.

en: Journal of Synthetic Organic Chemistry, Japan

ja: 有機合成化学協会誌


en: Catalytic Enantioselective Synthesis of Axially Chiral Allenes

en: Tetrahedron: Asymmetry

ja: Tetrahedron: Asymmetry


en: Transition-Metal-Catalyzed Enantioselective Synthesis of Compounds with Non-Centrochirality

en: Synthesis

ja: Synthesis


en: メタセシス反応を用いる面不斉メタロセン類の立体選択的合成法の開発

ja: メタセシス反応を用いる面不斉メタロセン類の立体選択的合成法の開発

en: 触媒

ja: 触媒


en: Product Class 1: Cumulenes

ja: Product Class 1: Cumulenes

en: Science of Synthesis, Houben-Weyl, Methods of Molecular Transformations


en: パラジウム錯体触媒による置換アレン類の立体選択的合成法の開発とその応用

ja: パラジウム錯体触媒による置換アレン類の立体選択的合成法の開発とその応用


en: Transition-Metal-Catalyzed Synthesis of Allenes

en: Modern Allene Chemistry

ja: Modern Allene Chemistry


en: パラジウム錯体触媒を用いたアレン合成反応~軸不斉アレンの触媒的不斉合成を目指して

en: 科学と工業

ja: 科学と工業


en: Chiral Pd(0) and Pd(II) Complexes

ja: Chiral Pd(0) and Pd(II) Complexes

en: Handbook of Organopalladium Chemistry for Organic Synthesis


en: パラジウム錯体を用いたアレン類の触媒的合成

ja: パラジウム錯体を用いたアレン類の触媒的合成

en: Organometallic News


en: Asymmetric Cross-Coupling Reactions

ja: Asymmetric Cross-Coupling Reactions

en: Catalytic Asymmetric Synthesis (2nd ed.)


en: NMRテクニックの有機金属化合物への応用

ja: NMRテクニックの有機金属化合物への応用

en: Journal of Synthetic Organic Chemistry, Japan