{"insert":{"user_id":"R000041402","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://tokushima-u.repo.nii.ac.jp/records/2011996","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/38500479","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=407539","label":"url"}],"paper_title":{"en":"Epoxide ring-opening reactions for abundant production of mugineic acids and nicotianamine probes.","ja":"Epoxide ring-opening reactions for abundant production of mugineic acids and nicotianamine probes."},"authors":{"en":[{"name":"Kayano Kimika"},{"name":"Tsutsumi Tomohiro"},{"name":"Murata Yoshiko"},{"name":"Ogasa Chie"},{"name":"Watanabe Takehiro"},{"name":"Sato Ryota"},{"name":"Karanjit Sangita"},{"name":"Namba Kosuke"}],"ja":[{"name":"茅野 公佳"},{"name":"堤 大洋"},{"name":"Murata Yoshiko"},{"name":"Ogasa Chie"},{"name":"Watanabe Takehiro"},{"name":"佐藤 亮太"},{"name":"カランジット サンギータ"},{"name":"難波 康祐"}]},"description":{"en":"A succinct synthetic approach to mugineic acids and 2'-hydroxynicotianamine was established. Unlike all other synthetic methods, this approach utilized epoxide ring-opening reactions to form two C-N bonds and is characterized by the absence of redox reactions. Mugineic acid was synthesized from three readily available fragments on a gram scale in 6 steps. The protected 2'-hydroxynicotianamine was also synthesized in 4 steps, and the dansyl group, serving as a fluorophore, was introduced through a click reaction after propargylation of the 2'-hydroxy group. The dansyl-labeled nicotianamine (NA) iron complexes were internalized by oocytes overexpressing ZmYS1 (from maize) or PAT1 (from human) transporters, indicating successful transport of the synthesized NA-probe through these transporters.","ja":"A succinct synthetic approach to mugineic acids and 2'-hydroxynicotianamine was established. Unlike all other synthetic methods, this approach utilized epoxide ring-opening reactions to form two C-N bonds and is characterized by the absence of redox reactions. Mugineic acid was synthesized from three readily available fragments on a gram scale in 6 steps. The protected 2'-hydroxynicotianamine was also synthesized in 4 steps, and the dansyl group, serving as a fluorophore, was introduced through a click reaction after propargylation of the 2'-hydroxy group. The dansyl-labeled nicotianamine (NA) iron complexes were internalized by oocytes overexpressing ZmYS1 (from maize) or PAT1 (from human) transporters, indicating successful transport of the synthesized NA-probe through these transporters."},"publication_date":"2024-03-29","publication_name":{"en":"Angewandte Chemie International Edition","ja":"Angewandte Chemie International Edition"},"volume":"63","number":"20","starting_page":"e202401411","ending_page":"e202401411","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1002/anie.202401411"],"issn":["1521-3773"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
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{"insert":{"user_id":"R000041402","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://tokushima-u.repo.nii.ac.jp/records/2006704","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/31474735","label":"url"},{"@id":"https://www.scopus.com/pages/publications/85071659929","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=353834","label":"url"}],"paper_title":{"en":"Asymmetric Total Syntheses and Structure Elucidations of (+)-Eurotiumide F and (+)-Eurotiumide G","ja":"Asymmetric Total Syntheses and Structure Elucidations of (+)-Eurotiumide F and (+)-Eurotiumide G"},"authors":{"en":[{"name":"Nakayama Atsushi"},{"name":"Satoh Hideo"},{"name":"Nagano Shuji"},{"name":"Karanjit Sangita"},{"name":"Imagawa Hiroshi"},{"name":"Namba Kosuke"}],"ja":[{"name":"中山 淳"},{"name":"佐藤 次朗"},{"name":"長野 秀嗣"},{"name":"カランジット サンギータ"},{"name":"今川 洋"},{"name":"難波 康祐"}]},"description":{"en":"Asymmetric total syntheses of dihydropyran containing natural products, (+)-eurotiumide F and (+)-eurotiumide G have been described. These total syntheses revealed the absolute configuration of eurotiumide F and G, and confirmed the reported structure of eurotiumide F and revised the reported structure of eurotiumide G. Highlight of these syntheses is thermal rearrangement with 4-methoxyisochroman-1-one derivative having propargyl ether on phenolic ether under thermal condition to construct dihydropyran ring. X-Ray crystallographic analysis of (+)-eurotiumide G clarified the stereochemistry at the C1-position.","ja":"Asymmetric total syntheses of dihydropyran containing natural products, (+)-eurotiumide F and (+)-eurotiumide G have been described. These total syntheses revealed the absolute configuration of eurotiumide F and G, and confirmed the reported structure of eurotiumide F and revised the reported structure of eurotiumide G. Highlight of these syntheses is thermal rearrangement with 4-methoxyisochroman-1-one derivative having propargyl ether on phenolic ether under thermal condition to construct dihydropyran ring. X-Ray crystallographic analysis of (+)-eurotiumide G clarified the stereochemistry at the C1-position."},"publication_date":"2019-07-16","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"67","number":"9","starting_page":"953","ending_page":"958","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.c18-00948"],"issn":["1347-5223"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"user_id":"R000041402","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://tokushima-u.repo.nii.ac.jp/records/2006665","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/30963767","label":"url"},{"@id":"https://www.scopus.com/pages/publications/85064687055","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=353833","label":"url"}],"paper_title":{"en":"A Concise Asymmetric Total Synthesis of (+)-Epilupinine","ja":"A Concise Asymmetric Total Synthesis of (+)-Epilupinine"},"authors":{"en":[{"name":"Tsutsumi Tomohiro"},{"name":"Karanjit Sangita"},{"name":"Nakayama Atsushi"},{"name":"Namba Kosuke"}],"ja":[{"name":"堤 大洋"},{"name":"カランジット サンギータ"},{"name":"中山 淳"},{"name":"難波 康祐"}]},"description":{"en":"Asymmetric total synthesis of (+)-epilupinine was achieved in just three steps using only commercially available common reagents. The total synthesis involved alkylations of N-nosylamide, ozone oxidation, and sequential reactions of the removal of the nosyl group, intramolecular dehydrative condensation, intramolecular Mannich reaction catalyzed by l-proline, and a reduction.","ja":"Asymmetric total synthesis of (+)-epilupinine was achieved in just three steps using only commercially available common reagents. The total synthesis involved alkylations of N-nosylamide, ozone oxidation, and sequential reactions of the removal of the nosyl group, intramolecular dehydrative condensation, intramolecular Mannich reaction catalyzed by l-proline, and a reduction."},"publication_date":"2019-04-09","publication_name":{"en":"Organic Letters","ja":"Organic Letters"},"volume":"21","number":"8","starting_page":"2620","ending_page":"2624","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/acs.orglett.9b00607"],"issn":["1523-7052"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"user_id":"R000041402","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://tokushima-u.repo.nii.ac.jp/records/2006666","label":"url"},{"@id":"https://www.scopus.com/pages/publications/85066142615","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=351723","label":"url"}],"paper_title":{"en":"Microwave-assisted Tertiary Carbon Radical Reaction for Construction of Quaternary Carbon Center","ja":"Microwave-assisted Tertiary Carbon Radical Reaction for Construction of Quaternary Carbon Center"},"authors":{"en":[{"name":"Sato Ryota"},{"name":"Okamoto Ryuji"},{"name":"Ishizuka Takumi"},{"name":"Nakayama Atsushi"},{"name":"Karanjit Sangita"},{"name":"Namba Kosuke"}],"ja":[{"name":"佐藤 亮太"},{"name":"岡本 龍治"},{"name":"石塚 匠"},{"name":"中山 淳"},{"name":"カランジット サンギータ"},{"name":"難波 康祐"}]},"publication_date":"2019-02","publication_name":{"en":"Chemistry Letters","ja":"Chemistry Letters"},"volume":"48","number":"5","starting_page":"414","ending_page":"417","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1246/cl.190040"],"issn":["1348-0715"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"user_id":"R000041402","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://tokushima-u.repo.nii.ac.jp/records/2006668","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/29701268","label":"url"},{"@id":"https://www.scopus.com/pages/publications/85049583439","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=342430","label":"url"}],"paper_title":{"en":"Direct Synthesis of Polycyclic Tropinones by a Condensation-[4+3]-Cycloaddition Cascade Reaction.","ja":"Direct Synthesis of Polycyclic Tropinones by a Condensation-[4+3]-Cycloaddition Cascade Reaction."},"authors":{"en":[{"name":"Okamoto Tsubasa"},{"name":"Shibata Miki"},{"name":"Karanjit Sangita"},{"name":"Nakayama Atsushi"},{"name":"Yoshida Masahiro"},{"name":"Namba Kosuke"}],"ja":[{"name":"岡本 翼"},{"name":"柴田 弥希"},{"name":"カランジット サンギータ"},{"name":"中山 淳"},{"name":"吉田 昌裕"},{"name":"難波 康祐"}]},"description":{"en":"A concise method of constructing polycyclic tropinone frameworks was developed. The single-step synthesis of polycyclic tropinone consists of an intramolecular [4+3] cycloaddition reaction of N-nosyl-pyrrole with oxyallyl cation that was generated in situ by an intermolecular condensation reaction of the nucleophilic functional groups on a tethered pyrrole with the aldehyde of 2-(silyloxy)-acrolein. This cascade reaction afforded various polycyclic tropinones including tri-, tetra-, and pentacyclic systems in high yields as single diastereomers.","ja":"A concise method of constructing polycyclic tropinone frameworks was developed. The single-step synthesis of polycyclic tropinone consists of an intramolecular [4+3] cycloaddition reaction of N-nosyl-pyrrole with oxyallyl cation that was generated in situ by an intermolecular condensation reaction of the nucleophilic functional groups on a tethered pyrrole with the aldehyde of 2-(silyloxy)-acrolein. This cascade reaction afforded various polycyclic tropinones including tri-, tetra-, and pentacyclic systems in high yields as single diastereomers."},"publication_date":"2018-04-27","publication_name":{"en":"Chemistry - A European Journal","ja":"Chemistry - A European Journal"},"volume":"24","number":"38","starting_page":"9508","ending_page":"9513","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1002/chem.201802011"],"issn":["1521-3765"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"user_id":"R000041402","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.scopus.com/pages/publications/85040597957","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=342433","label":"url"}],"paper_title":{"en":"Highly active and reusable hydrotalcite-supported Pd(0) catalyst for Suzuki coupling reactions of aryl bromides and chlorides","ja":"Highly active and reusable hydrotalcite-supported Pd(0) catalyst for Suzuki coupling reactions of aryl bromides and chlorides"},"authors":{"en":[{"name":"Karanjit Sangita"},{"name":"Kashihara Masaya"},{"name":"Nakayama Atsushi"},{"name":"Shrestha Kumar Lok"},{"name":"Ariga Katsuhiko"},{"name":"Namba Kosuke"}],"ja":[{"name":"カランジット サンギータ"},{"name":"柏原 雅也"},{"name":"中山 淳"},{"name":"Shrestha Kumar Lok"},{"name":"Ariga Katsuhiko"},{"name":"難波 康祐"}]},"publication_date":"2018-01","publication_name":{"en":"Tetrahedron","ja":"Tetrahedron"},"volume":"74","number":"9","starting_page":"948","ending_page":"954","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.tet.2017.12.056"],"issn":["0040-4020"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}