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徳島大学 > 大学院医歯薬学研究部 > 医学域 > 栄養科学部門 > 医科栄養学系 > 実践栄養学 >
徳島大学 > 栄養生命科学教育部 > 人間栄養科学専攻 >
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研究活動

専門分野

食品科学 (Food Science)

研究テーマ

著書・論文

学術論文(審査論文):

1. Satoh Ayano, Hayashi-Nishino Mitsuko, Shakuno Takuto, Masuda Junko, Koreishi Mayuko, Murakami Runa, Nakamura Yoshimasa, Nakamura Toshiyuki, Naomi Kanoh, Honjo Yasuko, Malsam Joerg, Yu Sidney and Nishino Kunihiko :
The Golgin Protein Giantin Regulates Interconnections Between Golgi Stacks,
Frontiers in Cell and Developmental Biology, Vol.7, 160, 2019.
(DOI: 10.3389/fcell.2019.00160,   Elsevier: Scopus)
2. Naomi Kanoh, Kunisue Narumi, Myojin Takumi, Chino Ayako, Munemasa Shintaro, Murata Yoshiyuki, Satoh Ayano, Moriya Hisao and Nakamura Yoshimasa :
Yeast screening system reveals the inhibitory mechanism of cancer cell proliferation by benzyl isothiocyanate through down-regulation of Mis12,
Scientific Reports, Vol.9, 8866, 2019.
(徳島大学機関リポジトリ: 113410,   DOI: 10.1038/s41598-019-45248-2,   PubMed: 31222108,   Elsevier: Scopus)
3. Naomi Kanoh, Yumi Kunimoto, Daisuke Takemoto, Yoshiko Ono, Hiroshi Shibata, Kohta Ohnishi and Yoshichika Kawai :
Sesamin Catechol Glucuronides Exert Anti-inflammatory Effects by Suppressing Interferon β and Inducible Nitric Oxide Synthase Expression through Deconjugation in Macrophage-like J774.1 Cells.,
Journal of Agricultural and Food Chemistry, 2019.
(徳島大学機関リポジトリ: 113271,   DOI: 10.1021/acs.jafc.8b07227,   PubMed: 30951310)
4. Yue Tang, Sho Naito, Naomi Kanoh, Seiji Ogawa, Shu Yamaguchi, Beiwei Zhu, Yoshiyuki Murata and Yoshimasa Nakamura :
Benzyl isothiocyanate attenuates the hydrogen peroxide-induced interleukin-13 expression through glutathione S-transferase P induction in T lymphocytic leukemia cells.,
Journal of Biochemical and Molecular Toxicology, Vol.32, No.6, e22054, 2018.
(DOI: 10.1002/jbt.22054,   PubMed: 29667773,   Elsevier: Scopus)
5. Xiaoyang Liu, Naomi Kanoh, Yujia Liu, Beiwei Zhu, Shintaro Munemasa, Toshiyuki Nakamura, Yoshiyuki Murata and Yoshimasa Nakamura :
Inhibition of phosphatidylinositide 3-kinase impairs the benzyl isothiocyanate-induced accumulation of autophagic molecules and Nrf2 in human colon cancer cells.,
Bioscience, Biotechnology, and Biochemistry, Vol.81, No.11, 2212-2215, 2017.
(DOI: 10.1080/09168451.2017.1374830,   PubMed: 28934922,   Elsevier: Scopus)
6. Yujia Liu, Momoko Yamanaka, Naomi Kanoh, Xiaoyang Liu, Beiwei Zhu, Shintaro Munemasa, Toshiyuki Nakamura, Yoshiyuki Murata and Yoshimasa Nakamura :
Benzyl isothiocyanate ameliorates acetaldehyde-induced cytotoxicity by enhancing aldehyde dehydrogenase activity in murine hepatoma Hepa1c1c7 cells.,
Food and Chemical Toxicology, Vol.108, No.Pt A, 305-313, 2017.
(DOI: 10.1016/j.fct.2017.08.016,   PubMed: 28821405,   Elsevier: Scopus)
7. Xiaoyang Liu, Chiaki Takano, Tomomi Shimizu, Shintaro Yokobe, Naomi Kanoh, Beiwei Zhu, Toshiyuki Nakamura, Shintaro Munemasa, Yoshiyuki Murata and Yoshimasa Nakamura :
Inhibition of phosphatidylinositide 3-kinase ameliorates antiproliferation by benzyl isothiocyanate in human colon cancer cells.,
Biochemical and Biophysical Research Communications, Vol.491, No.1, 209-216, 2017.
(DOI: 10.1016/j.bbrc.2017.07.078,   PubMed: 28712871,   Elsevier: Scopus)
8. Yue Tang, Sayaka Nakashima, Shunya Saiki, Yui Myoi, Naomi Kanoh, Shoko Kuwazuru, Beiwei Zhu, Hitoshi Ashida, Yoshiyuki Murata and Yoshimasa Nakamura :
3,4-Dihydroxyphenylacetic acid is a predominant biologically-active catabolite of quercetin glycosides.,
Food Research International, Vol.89, No.Pt 1, 716-723, 2016.
(DOI: 10.1016/j.foodres.2016.09.034,   PubMed: 28460970)
9. Naomi Kanoh, D-X Hou, S Munemasa, Y Murata and Y Nakamura :
Nuclear factor-kappaB sensitizes to benzyl isothiocyanate-induced antiproliferation in p53-deficient colorectal cancer cells.,
Cell Death & Disease, Vol.5, 2014.
(DOI: 10.1038/cddis.2014.495,   PubMed: 25412312)
10. Yue Tang, Naomi Kanoh, Motoko Yoshimoto, Beiwei Zhu, Yoshiyuki Murata and Yoshimasa Nakamura :
Benzyl isothiocyanate inhibits IL-13 expression in human basophilic KU812 cells.,
Bioscience, Biotechnology, and Biochemistry, Vol.79, No.1, 159-163, 2014.
(DOI: 10.1080/09168451.2014.963503,   PubMed: 25253661)
11. Yoshimasa Nakamura, Takeshi Ishii, Naomi Kanoh and Yoshiyuki Murata :
Thiol modification by bioactivated polyphenols and its potential role in skin inflammation.,
Bioscience, Biotechnology, and Biochemistry, Vol.78, No.6, 1067-1070, 2014.
(DOI: 10.1080/09168451.2014.905190,   PubMed: 25036136)
12. Hang Qi, Naomi Kanoh, Beiwei Zhu, Yoshiyuki Murata and Yoshimasa Nakamura :
(-)-Epigallocatechin-3-gallate ameliorates photodynamic therapy responses in an in vitro T lymphocyte model.,
Phytotherapy Research, Vol.28, No.10, 1486-1491, 2014.
(DOI: 10.1002/ptr.5152,   PubMed: 24700514)
13. Hang Qi, Qian Wu, Naomi Kanoh, Shunya Saiki, Beiwei Zhu, Yoshiyuki Murata and Yoshimasa Nakamura :
Ascorbic acid synergistically potentiates phloxine b-induced photocytotoxicity in human acute promyelocytic leukemia cells.,
Journal of Biochemical and Molecular Toxicology, Vol.28, No.4, 167-173, 2014.
(DOI: 10.1002/jbt.21549,   PubMed: 24488945)
14. Y. Tang, Naomi Kanoh, H. Qi, B. Zhu and Y. Murata :
Tea catechins inhibit cell proliferation through hydrogen peroxide-dependent and -independent pathways in human T lymphocytic leukemia Jurkat cells.,
Food Science and Technology Research, Vol.20, No.6, 1245-1249, 2014.
(DOI: 10.3136/fstr.20.1245)
15. Hang Qi, Beiwei Zhu, Naomi Kanoh, Yuko Shin, Yoshiyuki Murata and Yoshimasa Nakamura :
Involvement of intracellular oxidative stress-sensitive pathway in phloxine B-induced photocytotoxicity in human T lymphocytic leukemia cells.,
Food and Chemical Toxicology, Vol.50, No.6, 1841-1847, 2012.
(DOI: 10.1016/j.fct.2012.03.011,   PubMed: 22440610)
16. Naomi Kanoh, Masashi Okuhira, Chiharu Tsutsui, Yoshiyuki Murata and Yoshimasa Nakamura :
Cytotoxicity of benzyl isothiocyanate in normal renal proximal tubular cells and its modulation by glutathione.,
Journal of Agricultural and Food Chemistry, Vol.60, No.7, 1887-1892, 2012.
(DOI: 10.1021/jf2052042,   PubMed: 22296293)
17. Naomi Kanoh, Tomomi Shimizu, Noriyuki Miyoshi, Yoshiyuki Murata and Yoshimasa Nakamura :
-Tocopherol sensitizes human leukemia HL-60 cells to apoptosis induced by benzyl isothiocyanate.,
Bioscience, Biotechnology, and Biochemistry, Vol.76, No.2, 381-383, 2012.
(DOI: 10.1271/bbb.110665,   PubMed: 22313765)

学術論文(紀要・その他):

1. R. Sakai, S. Yokobe, Naomi Kanoh, N. Miyoshi and Y. Murata :
Luteolin overcomes resistance to benzyl isothiocyanate-induced apoptosis in human colorectal cancer HCT-116 cells.,
Journal of Food and Drug Analysis, Vol.20, No.Suppl., 389-393, 2012.
(Elsevier: Scopus)

総説・解説:

1. Toshiyuki Nakamura, Naomi Kanoh and Yoshimasa Nakamura :
Physiological relevance of covalent protein modification by dietary isothiocyanates.,
Journal of Clinical Biochemistry and Nutrition, Vol.62, No.1, 11-19, Dec. 2017.
(DOI: 10.3164/jcbn.17-91,   PubMed: 29371751)

国際会議:

1. Naomi Kanoh, Yuki Hashimoto, Haruka Yamamoto and Miyuki Uemura :
The effects of resveratrol and piceid on macrophage efferocytosis,
ICoFF2019, Dec. 2019.
2. Naomi Kanoh, Nuka Erika, Mao Aoki, Kotono Noguchi, Miyuki Uemura, 関口 博太, 須藤 慶太, 宇住 晃治, Kohta Ohnishi and 河合 慶親 :
Analysis of food-derived nucleic acids and their effects on claudin-4 mRNA expression in differentiated Caco-2 models,
ICoFF2019, Dec. 2019.
3. Maiko SAKAI, Kohta Ohnishi, Teppei FUKUDA, Masashi Masuda, Naomi Kanoh, Hisami Okumura, Yoshichika Kawai and Yutaka Taketani :
mTORC2 signaling is critical for lysosomal activation by isorhamnetin treatment in J774.1.,
FAOPS2019, Mar. 2019.

国内講演発表:

1. 叶 奈緒美 :
感動を原動力とした研究人生と研究テーマの模索状況,
フードサイエンスフォーラム 第23回学術集会, 2017年9月.
2. 叶 奈緒美, 國末 成美, 宗正 晋太郎, 村田 芳行, 河合 慶親, 佐藤 あやの, 守屋 央朗, 中村 宜督 :
食品成分ベンジルイソチオシアネートによる動原体を標的とした大腸がん細胞増殖阻害作用,
日本農芸化学会2017年度大会, 2017年3月.

科学研究費補助金 (KAKEN Grants Database @ NII.ac.jp)

  • 食品成分による染色体分配機構を標的とした制がん効果に関する研究 (研究課題/領域番号: 19K15789 )
  • ポリフェノールの抗動脈硬化作用に関わる転写因子の網羅的同定とその作用機構の解明 (研究課題/領域番号: 17K17923 )
  • 研究者番号(30780267)による検索