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Tokushima UniversityUniversity HospitalCentral Clinical FacilitiesDepartment of Patient Safety
Tokushima UniversityUniversity HospitalClinical DivisionDepartment of Internal MedicineGastroenterology
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Academic Paper (Judged Full Paper):

1. Jun Okazaki, Toshihito Tanahashi, Yasushi Sato, Jinsei Miyoshi, Tadahiko Nakagawa, Tetsuo Kimura, Hiroshi Miyamoto, Yasuteru Fujino, Fumika Nakamura, Masanori Takehara, beibei ma, Masahiro Bando, Shinji Kitamura, Koichi Okamoto, Naoki Muguruma, Masahiro Sogabe and Tetsuji Takayama :
MicroRNA-296-5p Promotes Cell Invasion and Drug Resistance by Targeting Bcl2-Related Ovarian Killer, Leading to a Poor Prognosis in Pancreatic Cancer.,
Digestion, Vol.101, No.6, 794-806, 2020.
(Tokushima University Institutional Repository: 114153,   DOI: 10.1159/000503225,   PubMed: 31563901,   Elsevier: Scopus)
2. Masanori Takehara, Yasushi Sato, Tetsuo Kimura, Kazuyoshi Noda, Hiroshi Miyamoto, Yasuteru Fujino, Jinsei Miyoshi, Fumika Nakamura, Hironori Wada, Yoshimi Bando, Tetsuya Ikemoto, Mitsuo Shimada, Naoki Muguruma and Tetsuji Takayama :
Cancer-associated Adipocytes Promote Pancreatic Cancer Progression Through SAA1 Expression,
Cancer Science, Vol.111, No.8, 2883-2894, 2020.
(Tokushima University Institutional Repository: 115328,   DOI: 10.1111/cas.14527,   PubMed: 32535957,   Elsevier: Scopus)
3. Hironori Tanaka, Koichi Okamoto, Yasushi Sato, Takahiro Tanaka, Tetsu Tomonari, Fumika Nakamura, Yasuteru Fujino, Yasuhiro Mitsui, Hiroshi Miyamoto, Naoki Muguruma, Akinori Morita, Hitoshi Ikushima and Tetsuji Takayama :
Synergistic anti-tumor activity of miriplatin and radiation through PUMA-mediated apoptosis in hepatocellular carcinoma.,
Journal of Gastroenterology, Vol.55, No.11, 1072-1086, 2020.
(Tokushima University Institutional Repository: 115325,   DOI: 10.1007/s00535-020-01705-8,   PubMed: 32666201,   Elsevier: Scopus)
4. Yoshihiko Miyamoto, Naoki Muguruma, Shota Fujimoto, Yasuyuki Okada, Yoshifumi Kida, Fumika Nakamura, Kumiko Tanaka, Tadahiko Nakagawa, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Yasushi Sato and Tetsuji Takayama :
Epidermal growth factor receptortargeted molecular imaging of colorectal tumors: Detection and treatment evaluation of tumors in animal models.,
Cancer Science, Vol.110, No.6, 1921-1930, 2019.
(Tokushima University Institutional Repository: 113790,   DOI: 10.1111/cas.14020,   PubMed: 30973663,   Elsevier: Scopus)
5. Hiroshi Miyamoto, Kumiko Tanaka, Fumika Nakamura, Takahiro Ikeda, Shinji Kitamura, Tetsuo Kimura, Koichi Okamoto, Masahiro Sogabe, Naoki Muguruma, Yoshimi Bando and Tetsuji Takayama :
Massive hemobilia following plastic stent removal in common bile duct cancer associated with primary sclerosing cholangitis (with video).,
Clinical Journal of Gastroenterology, Vol.12, No.1, 2019.
(DOI: 10.1007/s12328-018-0888-7,   PubMed: 30056613,   Elsevier: Scopus)
6. Yuri Matsumoto, Hiroshi Miyamoto, Akira Fukuya, Fumika Nakamura, Takahiro Goji, Shinji Kitamura, Tetsuo Kimura, Koichi Okamoto, Masahiro Sogabe, Naoki Muguruma, Mitsuo Shimada, Yoshimi Bando and Tetsuji Takayama :
Hemosuccus pancreaticus caused by a mucinous cystic neoplasm of the pancreas.,
Clinical Journal of Gastroenterology, Vol.10, No.2, 185-190, 2017.
(DOI: 10.1007/s12328-016-0711-2,   PubMed: 28054178,   Elsevier: Scopus)
7. Shinji Kitamura, Naoki Muguruma, Koichi Okamoto, Fumika Nakamura, Yasuyuki Okada, Tetsuo Kimura, Hiroshi Miyamoto and Tetsuji Takayama :
Endoscopic submucosal dissection through a gastrostomy for early gastric cancer in patients with pharyngeal stenosis.,
Gastrointestinal Endoscopy, Vol.79, No.2, 206-207, 2014.
(DOI: 10.1016/j.gie.2013.09.018,   PubMed: 24129250,   Elsevier: Scopus)

Proceeding of International Conference:

1. Yasutsugu Shimohata, Yuji Urabe, Shiro Oka, Takashi Hisabe, Atsushi Yamada, Hiro-O Matsushita, Hirotsugu Sakamoto, Joichiro Horii, Daisuke Watanabe, Hirotsugu Eda, Fumika Nakamura, Hironori Yamamoto, Tetsuji Takayama, Takayuki Matsumoto, Shinji Tanaka and Hideki Ishikawa :
Clinicopathological Characteristics of Serrated Polyposis Syndrome: Results of a Multicenter Study by the Colorectal Serrated Polyposis Syndrome (SPS) Study Group in Japan.,
Digestive Disease Week2021, May 2021.
2. Yasushi Sato, Kumiko Tanaka, Ishikawa Hideki, Satoshi Teramae, Fumika Nakamura, Yasuhiro Mitsui, Kagemoto Kaizo, Hiroshi Miyamoto, Koichi Okamoto, Naoki Muguruma, Ohmiya Naoki, Mutoh Michihiro and Tetsuji Takayama :
Small- intestinal involvement in familial adenomatous polyposis: characteristics and genotype- phenotype correlation from a Japanese cohort study,
DDW, May 2020.
3. Naoki Muguruma, Daisaku Fujimot, Tomoyuki Kawaguchi, Kaizoh Kagemoto, Satoshi Teramae, Yoshifumi Kida, Hironori Wada, Fumika Nakamura, Yasuteru Fujino, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Toshihito Tanahashi, Hiroshi Miyamoto, Yasushi Sato and Tetsuji Takayama :
Linked Color Imaging Improves Detection Rate of Sessile Serrated Adenoma/Polyp in the Colon: A Prospective Randomized Controlled Trial.,
UEG Week 2019, Barcelona, Oct. 2019.
4. Shinji Kitamura, Mototsugu Kato, Kenro Kawada, Masanori Takehara, Kaizo Kagemoto, Fumika Nakamura, Hironori Wada, Naoki Muguruma, Osamu Dohi, Shoko Ono, Hideki Ishikawa and Tetsuji Takayama :
Linked Color Imaging for the Detection of Gastric Neoplasm in High Risk Patients: A Prospective Multicenter Randomized Controlled Trial (LCI-FIND Trial).,
UEG Week2019, Barcelona, Oct. 2019.
5. Hironori Tanaka, Tetsu Tomonari, Takahiro Tanaka, Akihiro Hirao, Fumika Nakamura, Kumiko Tanaka, Koichi Okamoto, Yasushi Sato, Masahiro Sogabe, Hiroshi Miyamoto, Naoki Muguruma and Tetsuji Takayama :
Therapeutic efficacy of chemoradiotherapy with Miriplatin for hepatocellular carcinoma.,
digestive disease week2019, San Diego, May 2019.
6. Jinsei Miyoshi, Noriaki Murayama, Kumiko Tanaka, Takahiro Tanaka, Fumika Nakamura, Yasuteru Fujino, Keiichiro Matsumura, Miwako Kagawa, Tetsu Tomonari, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Yasushi Sato, Naoki Muguruma and Tetsuji Takayama :
Development of a Novel Mirna-Based Signature to Predict Invasion and Metastasis in Rectal Neuroendocrine Tumors.,
digestive disease week2019, Vol.156, No.6, 133, San Diego, May 2019.
(DOI: 10.1016/S0016-5085(19)37123-9)
7. Jun Okazaki, Toshihito Tanahasi, Yasushi Sato, Jinsei Miyoshi, Tadahiko Nakagawa, Tetsuo Kimura, Hiroshi Miyamoto, Yasuteru Fujino, Fumika Nakamura, Masanori Takehara, Masahiro Bando, Shinji Kitamura, Koichi Okamoto, Naoki Muguruma, Masahiro Sogabe and Tetsuji Takayama :
Interaction Between Pancreatic Cancer Cells and Adipocytes Promote Pancreatic Cancer Progression Through Overexpression of Saa1.,
digestive disease week2019, San Diego, May 2019.
8. Tetsuji Takayama, Toshihito Tanahashi, Koichi Okamoto, Shota Fujimoto, Tadahiko Nakagawa, Kaizoh Kagemoto, Yasuyuki Okada, Fumika Nakamura, Yasuteru Fujino, Shinji Kitamura, Hiroshi Miyamoto, Yasushi Sato and Naoki Muguruma :
S100P as a novel hypomethylation target in Sessile Serrated Adenoma(SSA/P)-cancer sequence: A genome-wide DNA methylation array analysis.,
UEG Week2018, Wien, Oct. 2018.
9. Fumika Nakamura, Koichi Okamoto, Kumiko Tanaka, Yasuteru Fujino, Jinsei Miyoshi, Shinji Kitamura, Hiroshi Miyamoto, Yasushi Sato, Naoki Muguruma and Tetsuji Takayama :
Clinicopathological Analyses of Colorectal Polyps and Cancers in Serrated Polyposis Syndrome.,
DIgestive Disease Week2018, Washington, D.C., Jun. 2018.
10. Daisaku Fujimoto, Kaizo Kagemoto, Yasuyuki Okada, Hironori Tanaka, Satoshi Teramae, Akihiro Hirao, Fumika Nakamura, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Naoki Muguruma and Tetsuji Takayama :
Usefulness of Linked Color Imaging System in Endoscopic Diagnosis of Sessile Serrated Adenoma/Polyp: A Novel Image Enhanced Technique.,
Digestive Disease Week2017, Chicago, May 2017.

Proceeding of Domestic Conference:

1. Hironori Tanaka, Tetsu Tomonari, kaizo kagemoto, Yasuyuki Okada, hironori wada, Fumika Nakamura, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Yasushi Sato, Naoki Muguruma and Tetsuji Takayama :
免疫チェックポイント阻害薬投与中の肝障害.,
第59回日本癌治療学会学術集会, Oct. 2021.
2. 矢野 庄悟, Fumika Nakamura, Yasushi Sato, akira fukuya, Yasuteru Fujino, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Naoki Muguruma and Tetsuji Takayama :
消化管悪性腫瘍における免疫チェックポイント阻害薬の効果と免疫関連副作用の関連性について.,
第17回日本消化管学会総会学術集会, Feb. 2021.
3. Fumika Nakamura, Koichi Okamoto, 影本 開三, Yoshifumi Kida, Kumiko Tanaka, Shinji Kitamura, Yasushi Sato, Hiroshi Miyamoto, Naoki Muguruma and Tetsuji Takayama :
Serrated polyposis syndrome に合併した大腸癌の臨床病理学的特徴ならびに発癌機序の検討.,
第17回日本消化管学会総会学術集会, Feb. 2021.
4. Fumika Nakamura, Kaizo Kagemoto and Tetsuji Takayama :
Serrated polyposis syndromeにおける癌の発症リスクと発癌機序の検討.,
第28回消化器関連学会週間(JDDW2020), Nov. 2020.
5. 横山 怜子, Fumika Nakamura, Yasushi Sato, Kazuhiro Kishi, 和田 浩典, Tetsu Tomonari, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Naoki Muguruma, Toshiya Okahisa and Tetsuji Takayama :
胃癌におけるICI治療の効果予測因子としてのirAEの意義とその後治療への影響.,
第58回日本癌治療学会学術集会, Oct. 2020.
6. 藤井 祥平, Fumika Nakamura, Yasushi Sato, 岸 和弘, Sumiko Yoshida, Yasuhiro Mitsui, Yasuteru Fujino, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Naoki Muguruma and Tetsuji Takayama :
<第23回若手奨励賞>胃癌における免疫チェックポイント阻害薬の効果と免疫関連副作用(irAE)との関連性についての検討.,
Shikoku Acta Medica, Vol.76, No.3-4, 173-178, Aug. 2020.
7. Takanori Kashihara, Yoshihiko Miyamoto, Shota Fujimoto, 和田 浩典, Tomoyuki Kawaguchi, Yoshifumi Kida, Fumika Nakamura, Kumiko Tanaka, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Yasushi Sato, Naoki Muguruma and Tetsuji Takayama :
大腸腫瘍に発現するepidermal growth factor receptor in colorectal tumors.,
第16回日本消化管学会総会学術集会, Feb. 2020.
8. Fumika Nakamura, Koichi Okamoto, Kaizoh Kagemoto, Kumiko Tanaka, Yasuteru Fujino, Shinji Kitamura, Hiroshi Miyamoto, Yasushi Sato, Naoki Muguruma and Tetsuji Takayama :
Serrated polyposis syndrome の臨床病理学的特徴ならびに発癌機序の検討.,
第16回日本消化管学会総会学術集会, Feb. 2020.
9. Tomoyuki Kawaguchi, Masanori Takehara, Kaizoh Kagemoto, Satoshi Teramae, Fumika Nakamura, Takahiro Tanaka, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Yasushi Sato, Naoki Muguruma and Tetsuji Takayama :
胸腺を含む5臓器にわたって10個の同時性多発重複癌を呈したLynch症候群の一例 .,
第57回日本癌治療学会学術集会, Oct. 2019.
10. Hironori Tanaka, Koichi Okamoto, 岡田 泰行, 宮本 佳彦, Yasuhiro Mitsui, Fumika Nakamura, Jinsei Miyoshi, Yasuteru Fujino, Takahiro Tanaka, Tetsu Tomonari, Shinji Kitamura, Hiroshi Miyamoto, Naoki Muguruma, Yasushi Sato and Tetsuji Takayama :
Therapeutic efficacy of miriplatin in combination with radiotherapy for advanced hepatocellular carcinoma.,
第17回日本臨床腫瘍学会学術集会, Jul. 2019.
11. Fumika Nakamura, Yasushi Sato and Tetsuji Takayama :
消化管腫瘍における免疫チェックポイント阻害薬の自己免疫疾患関連副作用(irAE)の経験,
第26回日本消化器関連学会週間(統合プログラム), Nov. 2018.
12. Kazuhide Iwasa, Naoki Igata, Tetsuya Honda, Taro Mizutani, Junji Nishioka, Masahiro Sogabe, Toshiya Okahisa, 大櫛 聖子, Yoshi Kida, 岡田 泰行, 宮本 佳彦, Kumiko Tanaka, Fumika Nakamura, 宮城 愛, Miwako Kagawa, Shinji Kitamura, Shinji Kitamura, Koichi Okamoto and Tetsuji Takayama :
潰瘍性大腸炎での内視鏡画像解析による大腸粘膜の炎症評価.,
第56回日本人工臓器学会大会, Nov. 2018.
13. 和田 浩典, Shinji Kitamura, Fumika Nakamura, Akira Fukuya, Masanori Takehara, Yasuyuki Okada, Yasuhiro Mitsui, Jinsei Miyoshi, Yasuteru Fujino, Kumiko Tanaka, Koichi Okamoto, Hiroshi Miyamoto, Yasushi Sato, Naoki Muguruma and Tetsuji Takayama :
CRT後咽頭狭窄を伴う表在型食道癌に対して細径内視鏡を用いたPDTが有効であった一例.,
第56回日本癌治療学会学術集会, Oct. 2018.
14. Satoshi Teramae, Kumiko Tanaka, 三橋 威志, Yasuhiro Mitsui, Fumika Nakamura, Yasuteru Fujino, Jinsei Miyoshi, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Yasushi Sato, Naoki Muguruma and Tetsuji Takayama :
新規APC遺伝子変異(C.1626+1G>A)を認めた家族性大腸腺腫症の一例.,
第6回日本家族性大腸腺腫症研究会学術集会, Sep. 2018.
15. Masanori Takehara, Yasushi Sato, 津保 友香, Akira Fukuya, 岡田 泰行, 宮本 佳彦, Yasuhiro Mitsui, Yasuteru Fujino, Fumika Nakamura, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Naoki Muguruma and Tetsuji Takayama :
膵癌と脂肪細胞の相互作用はSAA1の発現を誘導することにより膵癌の浸潤を促進させる.,
第16回日本臨床腫瘍学会学術集会, Jul. 2018.
16. 津保 友香, Yasuhiro Mitsui, Akira Fukuya, Masanori Takehara, 岡田 泰行, Jinsei Miyoshi, Yasuteru Fujino, Fumika Nakamura, Kumiko Tanaka, Shinji Kitamura, Koichi Okamoto, Hiroshi Miyamoto, Yasushi Sato, Naoki Muguruma and Tetsuji Takayama :
切除不能進行神経内分泌癌に対するIrinotecan+Cisplatin併用療法の後方視的検討.,
第16回日本臨床腫瘍学会学術集会, Jul. 2018.
17. Fumika Nakamura, Koichi Okamoto, Kaizoh Kagemoto, Noriaki Murayama, Kumiko Tanaka, Yasuteru Fujino, Shinji Kitamura, 三宮 勝隆, Yasushi Sato, Hiroshi Miyamoto, Naoki Muguruma and Tetsuji Takayama :
Serrated polyposis syndromeにおける遺伝性及び発癌機序の検討.,
第14回日本消化管学会総会学術集会, Feb. 2018.
18. 岡田 泰行, Tetsuo Kimura, Koichi Okamoto, Fumika Nakamura, Yasuteru Fujino, Kumiko Tanaka, Jinsei Miyoshi, Yasuhiro Mitsui, Shinji Kitamura, Hiroshi Miyamoto, Yasushi Sato, Naoki Muguruma and Tetsuji Takayama :
抗EGFR抗体薬治療におけるEarly tumor shrinkage(ETS)とEGFR内在化の関連について,
第88回大腸癌研究会, Jan. 2018.
19. 高岡 慶史, 影本 開三, Yasuhiro Mitsui, Kumiko Tanaka, Fumika Nakamura, Yasuteru Fujino, Shinji Kitamura, Tetsuo Kimura, Koichi Okamoto, Masako Kimura, 仁木 美也子, Hiroshi Miyamoto, Naoki Muguruma, 石川 正志 and Tetsuji Takayama :
免疫チェックポイント阻害薬で加療した直腸肛門部悪性黒色腫の4例.,
第55回日本癌治療学会学術集会, Oct. 2017.
20. Yasuteru Fujino, Kumiko Tanaka, Fumika Nakamura, Shinji Kitamura, Tetsuo Kimura, Koichi Okamoto, Hiroshi Miyamoto, Yasushi Sato, Naoki Muguruma and Tetsuji Takayama :
大腸粘膜下層浸潤癌リンパ節転移に関わるmicroRNAの網羅的解析.,
第87回大腸癌研究会, Jul. 2017.
21. Shinji Kitamura, Naoki Muguruma, 松本 友里, 松本 早代, 岡崎 潤, 髙岡 遠, 村山 典聡, 香川 美和子, Yasuteru Fujino, Jinsei Miyoshi, Fumika Nakamura, 大塚 加奈子, Hiroshi Miyamoto, Toshiya Okahisa and Tetsuji Takayama :
内視鏡切除された直腸カルチノイド(NET-G1)の臨床経過に関する検討,
第87回日本消化器内視鏡学会総会, May 2014.
22. 宮本 佳彦, Naoki Muguruma, Shinji Kitamura, 松本 友里, 松本 早代, Fumika Nakamura, 髙岡 遠, Yasuteru Fujino, Jinsei Miyoshi, Kumiko Tanaka, Takahiro Goji, Hiromi Yano, 香川 美和子, Hiroshi Miyamoto, Toshiya Okahisa and Tetsuji Takayama :
大腸癌に対する内視鏡分子イメージング技術の開発,
第87回日本消化器内視鏡学会総会, May 2014.
23. Shinji Kitamura, Naoki Muguruma, 松本 友里, 松本 早代, 岡崎 潤, 髙岡 遠, 香川 美和子, Yasuteru Fujino, Jinsei Miyoshi, Fumika Nakamura, Kumiko Tanaka, Hiroshi Miyamoto, Toshiya Okahisa and Tetsuji Takayama :
バレット食道癌における欧米と日本のマネジメントの相違に関する検討,
第87回日本消化器内視鏡学会総会, May 2014.
24. 藤野 泰輝, 大塚 加奈子, 田中 久美子, Fumika Nakamura, 三好 人正, 香川 美和子, Takahiro Goji, 髙岡 遠, Hiromi Yano, Shinji Kitamura, Hiroshi Miyamoto, Naoki Muguruma, Toshiya Okahisa and Tetsuji Takayama :
Sessile serrated adenoma/polyp(SSA/P)の前病変としてのAberrant crypt foci(ACF)の解析,
第10回日本消化管学会総会学術集会, Feb. 2014.
25. 松本 早代, Naoki Muguruma, 松本 友里, 岡崎 潤, 田中 久美子, Fumika Nakamura, 藤野 泰輝, 三好 人正, 香川 美和子, Takahiro Goji, 髙岡 遠, 村山 典聡, Hiromi Yano, Shinji Kitamura, Hiroshi Miyamoto, Toshiya Okahisa and Tetsuji Takayama :
内視鏡治療された直腸カルチノイド(NET-G1)の臨床経過に関する検討,
第80回大腸癌研究会, Jan. 2014.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)