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en: A case of thyroid-like low-grade nasopharyngeal papillary adenocarcinoma of the posterior end of the nasal septum

ja: 鼻中隔後端に生じたThyroid-like low-grade nasopharyngeal papillary adenocarcinoma例

en: JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY

ja: 頭頸部外科


en: Effect of Surgical Training Using a Virtual Reality Sinus Simulator in Medical Education

ja: バーチャルリアリティーを用いた内視鏡下鼻副鼻腔手術シミュレーターによる医学教育実習の効果

en: Japanese Journal of Rhinology

ja: 日本鼻科学会会誌


en: Dietary Supplementation with Monosodium Glutamate Suppresses Chemotherapy-Induced Downregulation of the T1R3 Taste Receptor Subunit in Head and Neck Cancer Patients.

en: (Background) We investigated the effect of dietary supplementation with monosodium glutamate (MSG) on chemotherapy-induced downregulation of the T1R3 taste receptor subunit expression in the tongue of patients with advanced head and neck cancer. (Methods) Patients undergoing two rounds of chemoradiotherapy were randomly allocated to a control or intervention group (dietary supplementation with MSG at 2.7 g/day during the second round of chemotherapy). The relative expression of T1R3, a subunit of both umami and sweet taste receptors, in the tongue was assessed by quantitative polymerase chain reaction analysis. Dysgeusia was assessed with a visual analog scale and daily energy intake was evaluated. (Results) T1R3 expression levels in the tongue, taste sensitivity, and daily energy intake were significantly reduced after the first round of chemotherapy compared with before treatment. Furthermore, these parameters significantly decreased after the second round of chemotherapy, but the extent of decrease was significantly attenuated in the MSG group compared with the control group. (Conclusions) MSG supplementation suppresses chemotherapy-induced dysgeusia, possibly due to the inhibition of the T1R3-containing taste receptor downregulation in the tongue, thereby increasing energy intake in patients with advanced head and neck cancer.

en: Nutrients

ja: Nutrients


en: Two cases of allergic fungal rhinosinusitis

ja: 当院で経験したアレルギー性真菌性鼻副鼻腔炎例

en: Tokushima Red Cross Hospital Medical Journal

ja: 徳島赤十字病院医学雑誌