type: misc

label: url

en: A patient with esophageal hemangioma treated by endoscopic mucosal resection: a case report and review of the literature.

en: In a 58-year-old male, upper digestive endoscopy revealed a protruding lesion in the esophagus on a medical examination. The patient was referred to the Department of Surgery in our hospital to undergo surgery. On the initial consultation, upper digestive endoscopy showed a smooth, soft, black purple, type II protruding lesion measuring approximately 25 mm at 35 cm apart from the incisor. For diagnostic treatment and patient's request, endoscopic mucosal resection (EMR) was performed. The resected specimen measured 25 mm x 25 mm. The histological findings suggested cavernous hemangioma. To treat esophageal hemangioma, esohagectomy, tumor enucleation, or sclerotherapy has been performed. However, recently, thorough preoperative examination, such as endoscopic ultrasonography (EUS), has facilitated endoscopic resection, such as EMR.

en: The Journal of Medical Investigation : JMI


en: Principle and Clinical Usefulness of the Infrared Fluorescence Endoscopy

en: Since there is no infrared fluorescence materials in the living body, infrared fluorescence labeling materials are very useful for making a diagnosis of a micro cancer. We have developed an infrared fluorescence endoscope (IRFE) and indocyanin green (ICG)-derivative as infrared fluorescence labeling materials to evaluate gastrointestinal neoplastic lesions. The study aims were to apply an IRFE and to demonstrate its usefulness in detecting cancerous tissue using an antibody coupled with ICG-derivative. IRFE consisted of an infrared endoscope equipped with excitation (710-790 nm) and barrier (810-920 nm) filters and an intensified CCD camera. We have developed ICG N-hydroxy sulfo succinimide ester (ICG-sulfo-OSu) and 3-ICG-acyl-1, 3-thiazolidine-2-thione (ICG-ATT) as an infrared fluorescent-labeling reagent. ICG-derivative-labeled mouse anti-human carcinoembryonic antigen (CEA) antibody and MUC1 antibody were employed in this study. Moreover, we examined the ability of a reinforcement agent, octylglucoside, to intensity fluorescence from the labeled antibody. Biopsy specimens of gastric cancer were stained with anti-CEA antibody by the avidin-biotinylated peroxidase complex method. Among the positive specimens, freshly resected stomach from three cases were used for the infrared (IR) imaging analysis. The incubation of freshly resected stomach specimens with ICG-anti-CEA antibody-complex resulted in positive staining of the tumor sites by IRFE, and the IR fluorescent images correlated well with the tumor sites. The immunohistochemical studies suggested that the intensity of IR fluorescence of ICG-ATT-MUC1 was stronger than that of ICG-sulfo-OSu. In tumor sections, the reinforcement agent intensified fluorescence, ever at low antibody concentrations. Therefore, we conclude that an anti-CEA (and/or MUC1) antibody with affinity for cancerous lesions and labeled with ICG-derivative can be imaged with this IRFE. Specific antibodies tagged with ICG-derivative with the reinforcement agent can label cancer cells and generate a strong enough fluorescent signal to detect small cancers when examined with an IR fluorescence endoscope.

ja: The Journal of Medical Investigation : JMI


en: Hepatitis and Hepatocellular carcinoma

ja: 特集2:健康であるために何をすべきか? 肝炎·肝癌

en: Shikoku Acta Medica

ja: 四国医学雑誌


en: 赤外線蛍光内視鏡の原理と応用

ja: 赤外線蛍光内視鏡の原理と応用

en: Biomedical THERMOLOGY

ja: Biomedical THERMOLOGY


en: C型肝炎ウイルス持続感染患者の肝線維化における女性ホルモンの役割

ja: C型肝炎ウイルス持続感染患者の肝線維化における女性ホルモンの役割


en: 消化器病研究施設紹介 --- 徳島大学医学部臓器病態治療医学教室

ja: 消化器病研究施設紹介 --- 徳島大学医学部臓器病態治療医学教室

en: Frontiers in Gastroenterology

ja: Frontiers in Gastroenterology


en: 不整脈源性右室心筋症

ja: 不整脈源性右室心筋症

en: Journal of Clinical and Experimental Medicine

ja: 医学のあゆみ


en: データ解説

ja: データ解説


en: 女性ホルモン·エストラジオールの肝発癌抑制作用

ja: 女性ホルモン·エストラジオールの肝発癌抑制作用

en: 性差医学

ja: 性差医学


en: 女性ホルモン·エストラジオールの抗酸化作用と肝線維化抑制作用

ja: 女性ホルモン·エストラジオールの抗酸化作用と肝線維化抑制作用

en: Sex Difference and Similarity


en: 経皮的胃電図

ja: 経皮的胃電図

en: Medical Technology

ja: Medical Technology


en: 黄疸と徐脈

ja: 黄疸と徐脈

en: Japan Medical Journal

ja: 日本医事新報


en: グアナーゼ(GU)

ja: グアナーゼ(GU)

en: Nihon Rinsho. Japanese Journal of Clinical Medicine

ja: 日本臨牀


en: 非典型的B型慢性肝炎

ja: 非典型的B型慢性肝炎


en: Brugada症候群

ja: Brugada症候群


en: 腸管嚢胞様気腫 --- 吐血と下血

ja: 腸管嚢胞様気腫 --- 吐血と下血

en: 消化器診療プラクティス 7

ja: 消化器診療プラクティス 7


en: 膵管内発育を主とし特異な形態を呈した膵腺房細胞癌の1例

ja: 膵管内発育を主とし特異な形態を呈した膵腺房細胞癌の1例

en: 消化器画像

ja: 消化器画像

misc_type: others


en: Hepatobiliary cystadenocarcinoma without mesenchymal stroma showing a good prognosis

en: Journal of Gastroenterology and Hepatology


en: 嚢胞変性により特異な形態を呈した胃GISTの1例

ja: 嚢胞変性により特異な形態を呈した胃GISTの1例

en: 胃と腸

ja: 胃と腸


en: 14-18 がん情報の診断治療用光学機器の開発

ja: 14-18 がん情報の診断治療用光学機器の開発

en: 厚生労働省がん研究助成金による研究報告集

ja: 厚生労働省がん研究助成金による研究報告集


en: Jejunal extramedullary plasmacytoma

ja: Jejunal extramedullary plasmacytoma

en: Gastrointestinal Endoscopy

ja: Gastrointestinal Endoscopy


en: A Patient with sustained ventricular tachycardia:identification of a responder to aminodarone using signal-averaged electrocardiogram

en: A 75-year-old man suffered sustained ventricular tachycardia with syncopal attack. Ventricular tachycardias appeared repeatedly, and an electrical defibrillator was used after an anti-arrhythmic drug, such as lidocaine or mexiletine, proved ineffective. The tachycardias had multiple origins, and the signal-averaged electrocardiogram (SAECG) showed ventricular late potential before the administration of amiodarone. After administration, the filtered QRS and duration of the late potential increased, but the recurrence of tachycardias was suppressed. The reason for this is thought to be that amiodarone blocked the sodium channel and delayed conduction, consequently blocking reentry, because amiodaron has antiarrhymic properties with a prolongation of refractoriness and minimal effect on conduction velocity in ventricular myocardium, and inhibits sympathetic activity, and blocks L-type calcium channel besides the depression of the fast sodium channel. In this case, SAECG predicted to some degree whether or not this patient's ventricular tachycardia would respond to amiodarone.

en: The Journal of Medical Investigation : JMI


en: がんの診断治療用光学機器の開発に関する研究 平成13年度

ja: がんの診断治療用光学機器の開発に関する研究 平成13年度

en: 厚生労働省がん研究助成金による研究報告集

ja: 厚生労働省がん研究助成金による研究報告集


en: Helicobacter pylori内視鏡研究会報告

ja: Helicobacter pylori内視鏡研究会報告

en: Gastroenterlogical Endoscopy

ja: Gastroenterlogical Endoscopy


en: THPによる健康増進の効果と生活習慣病の予防に関する調査研究報告書

ja: THPによる健康増進の効果と生活習慣病の予防に関する調査研究報告書

en: 調査研究報告書

ja: 調査研究報告書