=== Generating (published_papers) === === Generating (teaching_experience) === === Generating (education) === === Generating (misc) === === Generating (research_projects) === === Generating (committee_memberships) === === Generating (awards) === === Generating (association_memberships) === === Generating (presentations) === ==== begin registerFile(/WWW/pub2/data/ERD/person/60298/researchmap/published_papers-propagate.jsonl) ==== line:1, {"insert":{"user_id":"5000020102","type":"published_papers","id":"52069129"},"force":{"see_also":[{"@id":"https://doi.org/10.3390/jimaging12010048","label":"url"},{"@id":"https://tokushima-u.repo.nii.ac.jp/records/2013839","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=459288","label":"url"}],"paper_title":{"en":"Graph-Enhanced Expectation Maximization for Emission Tomography","ja":"Graph-Enhanced Expectation Maximization for Emission Tomography"},"authors":{"en":[{"name":"Kasai Ryosuke"},{"name":"Otsuka Hideki"}],"ja":[{"name":"笠井 亮佑"},{"name":"大塚 秀樹"}]},"publication_date":"2026-01-19","publication_name":{"en":"Journal of Imaging","ja":"Journal of Imaging"},"volume":"12","number":"1","starting_page":"48","ending_page":"48","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3390/jimaging12010048"],"issn":["2313-433X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:2, {"insert":{"user_id":"5000020102","type":"published_papers","id":"50574308"},"force":{"see_also":[{"@id":"https://tokushima-u.repo.nii.ac.jp/records/2011513","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/37940520","label":"url"},{"@id":"https://www.scopus.com/pages/publications/85176456760","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=403775","label":"url"}],"paper_title":{"en":"Early Prediction of Radiotherapeutic Efficacy in a Mouse Model of Non-Small Cell Lung Carcinoma Using 18F-FLT and 18F-FDG PET / CT","ja":"Early Prediction of Radiotherapeutic Efficacy in a Mouse Model of Non-Small Cell Lung Carcinoma Using 18F-FLT and 18F-FDG PET / CT"},"authors":{"en":[{"name":"Otani Tamaki"},{"name":"Ikushima Hitoshi"},{"name":"Bando Yoshimi"},{"name":"Yamashita Michiko"},{"name":"Kuwahara Kenmei"},{"name":"Otsuka Hideki"},{"name":"Kondo Kazuya"},{"name":"Miyoshi Hirokazu"}],"ja":[{"name":"大谷 環樹"},{"name":"生島 仁史"},{"name":"坂東 良美"},{"name":"山下 理子"},{"name":"Kuwahara Kenmei"},{"name":"大塚 秀樹"},{"name":"近藤 和也"},{"name":"三好 弘一"}]},"description":{"en":"This study investigated the usefulness of [18F]-3'-deoxy-3'-fluorothymidine (18F-FLT) and [18F]-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging for predicting the therapeutic efficacy of non-small cell lung cancer (NSCLC) irradiation at an early stage after radiation treatment. Mice were xenografted with the human lung adenocarcinoma line A549 or large cell lung cancer line FT821. Tumour uptake of 18F-FLT and 18F-FDG was imaged using PET/CT before and 1 week after irradiation. In A549 tumours, 18F-FLT uptake was significantly decreased, and 18F-FDG uptake was unchanged post-irradiation compared with pre-irradiation. In FT821 tumours, uptake of both 18F-FLT and 18F-FDG uptake was substantially decreased post-irradiation compared with pre-irradiation. In both xenografts, tumour volumes in the irradiated groups were significantly decreased compared with those in the control group. 18F-FLT is expected to contribute to individual NSCLC therapy because it accurately evaluates the decrease in tumour activity that cannot be captured by 18F-FDG. 18F-FDG may be useful for evaluating surviving cells without being affected by the inflammatory reaction at an extremely early stage, approximately 1 week after irradiation. Combined use of 18F-FLT and 18F-FDG PET/CT imaging may increase the accurate prediction of radiotherapy efficacy, which may lead to improved patient outcomes and minimally invasive personalised therapy. J. Med. Invest. 70 : 361-368, August, 2023.","ja":"This study investigated the usefulness of [18F]-3'-deoxy-3'-fluorothymidine (18F-FLT) and [18F]-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) imaging for predicting the therapeutic efficacy of non-small cell lung cancer (NSCLC) irradiation at an early stage after radiation treatment. Mice were xenografted with the human lung adenocarcinoma line A549 or large cell lung cancer line FT821. Tumour uptake of 18F-FLT and 18F-FDG was imaged using PET/CT before and 1 week after irradiation. In A549 tumours, 18F-FLT uptake was significantly decreased, and 18F-FDG uptake was unchanged post-irradiation compared with pre-irradiation. In FT821 tumours, uptake of both 18F-FLT and 18F-FDG uptake was substantially decreased post-irradiation compared with pre-irradiation. In both xenografts, tumour volumes in the irradiated groups were significantly decreased compared with those in the control group. 18F-FLT is expected to contribute to individual NSCLC therapy because it accurately evaluates the decrease in tumour activity that cannot be captured by 18F-FDG. 18F-FDG may be useful for evaluating surviving cells without being affected by the inflammatory reaction at an extremely early stage, approximately 1 week after irradiation. Combined use of 18F-FLT and 18F-FDG PET/CT imaging may increase the accurate prediction of radiotherapy efficacy, which may lead to improved patient outcomes and minimally invasive personalised therapy. J. Med. Invest. 70 : 361-368, August, 2023."},"publication_date":"2023-08","publication_name":{"en":"The Journal of Medical Investigation : JMI","ja":"The Journal of Medical Investigation : JMI"},"volume":"70","number":"3,4","starting_page":"361","ending_page":"368","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2152/jmi.70.361"],"issn":["1349-6867"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:3, {"insert":{"user_id":"5000020102","type":"published_papers","id":"50574326"},"force":{"see_also":[{"@id":"https://tokushima-u.repo.nii.ac.jp/records/2007835","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/31031701","label":"url"},{"@id":"https://www.scopus.com/pages/publications/85067834785","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=366241","label":"url"}],"paper_title":{"en":"Potential Utility of 123I-MIBG Scintigraphy as a Predictor of Falls in Parkinson's Disease","ja":"Potential Utility of 123I-MIBG Scintigraphy as a Predictor of Falls in Parkinson's Disease"},"authors":{"en":[{"name":"Murakami Nagahisa"},{"name":"Sako Wataru"},{"name":"Haji Shotaroh"},{"name":"Furukawa Takahiro"},{"name":"Otomi Yoichi"},{"name":"Otsuka Hideki"},{"name":"Izumi Yuishin"},{"name":"Harada Masafumi"},{"name":"Kaji Ryuji"}],"ja":[{"name":"村上 永久"},{"name":"佐光 亘"},{"name":"土師 正太郎"},{"name":"Furukawa Takahiro"},{"name":"Otomi Yoichi"},{"name":"大塚 秀樹"},{"name":"和泉 唯信"},{"name":"原田 雅史"},{"name":"梶 龍兒"}]},"description":{"en":"Falls are associated with poor prognosis in patients with Parkinson's disease (PD). Although several factors related to falls were reported in patients with PD, objective predictors of falls are not identified. We aimed to determine whether I-meta-iodobenzylguanidine (MIBG) cardiac scintigraphy could be a useful biomarker to predict falls. Forty-five patients with PD were enrolled in this study. These subjects were followed up more than 5 years after MIBG scintigraphy and were divided into two groups: one with decreased uptake of MIBG and the other without decreased uptake of MIBG. The cut-off value for the delayed heart-to-mediastinum ratio was 1.8. Kaplan-Meier analysis and a log-rank test were performed to test the predictive power of MIBG cardiac scintigraphy for falls. Univariate analysis was selected because we did not have appropriate data for adjustment, such as motor and cognitive assessment. The group with decreased uptake of MIBG had a significantly higher incidence of falls than that without decreased uptake of MIBG ( = 0.022, log-rank test). Although the limitations of this study were lack of several key factors including motor and cognitive assessment, MIBG cardiac scintigraphy may be used to predict falls in patients with PD.","ja":"Falls are associated with poor prognosis in patients with Parkinson's disease (PD). Although several factors related to falls were reported in patients with PD, objective predictors of falls are not identified. We aimed to determine whether I-meta-iodobenzylguanidine (MIBG) cardiac scintigraphy could be a useful biomarker to predict falls. Forty-five patients with PD were enrolled in this study. These subjects were followed up more than 5 years after MIBG scintigraphy and were divided into two groups: one with decreased uptake of MIBG and the other without decreased uptake of MIBG. The cut-off value for the delayed heart-to-mediastinum ratio was 1.8. Kaplan-Meier analysis and a log-rank test were performed to test the predictive power of MIBG cardiac scintigraphy for falls. Univariate analysis was selected because we did not have appropriate data for adjustment, such as motor and cognitive assessment. The group with decreased uptake of MIBG had a significantly higher incidence of falls than that without decreased uptake of MIBG ( = 0.022, log-rank test). Although the limitations of this study were lack of several key factors including motor and cognitive assessment, MIBG cardiac scintigraphy may be used to predict falls in patients with PD."},"publication_date":"2019-04-12","publication_name":{"en":"Frontiers in Neurology","ja":"Frontiers in Neurology"},"volume":"10","starting_page":"376","ending_page":"376","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3389/fneur.2019.00376"],"issn":["1664-2295"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:4, {"insert":{"user_id":"5000020102","type":"published_papers","id":"50574339"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23674658","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=264177","label":"url"}],"paper_title":{"en":"18F-fluorodeoxyglucose positron emission tomography/computed tomography and the relationship between fluorodeoxyglucose uptake and the expression of hypoxia-inducible factor-1, glucose transporter-1 and vascular endothelial growth factor in thymic epithelial tumours.","ja":"18F-fluorodeoxyglucose positron emission tomography/computed tomography and the relationship between fluorodeoxyglucose uptake and the expression of hypoxia-inducible factor-1, glucose transporter-1 and vascular endothelial growth factor in thymic epithelial tumours."},"authors":{"en":[{"name":"Toba Hiroaki"},{"name":"Kondo Kazuya"},{"name":"Sadohara Yohei"},{"name":"Otsuka Hideki"},{"name":"Morimoto Masami"},{"name":"Kajiura Koichiro"},{"name":"Nakagawa Yasushi"},{"name":"Yoshida Mitsuteru"},{"name":"Kawakami Yukikiyo"},{"name":"Takizawa Hiromitsu"},{"name":"Kenzaki Koichiro"},{"name":"Sakiyama Shoji"},{"name":"Bando Yoshimi"},{"name":"Tangoku Akira"}],"ja":[{"name":"鳥羽 博明"},{"name":"近藤 和也"},{"name":"Sadohara Yohei"},{"name":"大塚 秀樹"},{"name":"Morimoto Masami"},{"name":"梶浦 耕一郎"},{"name":"中川 靖士"},{"name":"吉田 光輝"},{"name":"川上 行奎"},{"name":"滝沢 宏光"},{"name":"監﨑 孝一郎"},{"name":"先山 正二"},{"name":"坂東 良美"},{"name":"丹黒 章"}]},"description":{"en":"OBJECTIVES: The objective of this study was to evaluate the usefulness of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) and the relationships among the expressions of hypoxia-inducible factor-1 (HIF-1), glucose transporter-1 (Glut-1) and vascular endothelial growth factor (VEGF), histological type, other clinical factors and FDG uptake in thymic epithelial tumours. METHODS: Thirty-three patients who underwent FDG-PET/CT before treatment were reviewed. All types of tumours were reclassified into three subgroups: low-risk thymomas (types A, AB and B1), high-risk thymomas (types B2 and B3) and thymic carcinomas. Tumour contour, pattern of FDG uptake, tumour size and maximum standardized uptake value (SUVmax) were obtained. Expressions of HIF-1, Glut-1 and VEGF were analysed immunohistochemically, and these expressions were evaluated using grading scales. RESULTS: FDG uptake was visually recognized in all (100%) tumours. A homogeneous pattern of FDG uptake was increasingly observed in the order of low-risk thymomas to high-risk thymomas to thymic carcinomas (P = 0.016). SUVmax for thymic carcinomas was significantly higher than that for thymomas (P = 0.008). With the optimal cut-off value of SUVmax of 5.6, the sensitivity, specificity and accuracy for diagnosing thymic carcinoma were 0.75, 0.80 and 0.79, respectively. Regarding the mean scoring of HIF-1, Glut-1 and VEGF, increasing trends were observed in the order of low-risk thymomas to high-risk thymomas to thymic carcinomas. Tumour size revealed a significant correlation with SUVmax (r = 0.60, P < 0.001), and the expression of HIF-1 showed a moderate association, but the expression of Glut-1 showed no correlation with SUVmax. Regarding correlations between the expression of the three markers, there were moderate associations between HIF-1 and Glut-1, and HIF-1 and VEGF, and a significant correlation between Glut-1 and VEGF (r = 0.60, P < 0.001). In type B1 thymoma, HIF-1 and Glut-1 were partly expressed in non-neoplastic immature lymphocytes. CONCLUSIONS: FDG-PET/CT should be performed in patients with tumours in the anterior mediastinum because the pattern of FDG uptake and SUVmax are useful in the differential diagnosis of thymic epithelial tumours. Furthermore, the expressions of HIF-1, Glut-1 and VEGF might be associated with malignancy of thymic epithelial tumours. In contrast, FDG uptake might be dependent on tumour size rather than Glut-1 overexpression.","ja":"OBJECTIVES: The objective of this study was to evaluate the usefulness of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) and the relationships among the expressions of hypoxia-inducible factor-1 (HIF-1), glucose transporter-1 (Glut-1) and vascular endothelial growth factor (VEGF), histological type, other clinical factors and FDG uptake in thymic epithelial tumours. METHODS: Thirty-three patients who underwent FDG-PET/CT before treatment were reviewed. All types of tumours were reclassified into three subgroups: low-risk thymomas (types A, AB and B1), high-risk thymomas (types B2 and B3) and thymic carcinomas. Tumour contour, pattern of FDG uptake, tumour size and maximum standardized uptake value (SUVmax) were obtained. Expressions of HIF-1, Glut-1 and VEGF were analysed immunohistochemically, and these expressions were evaluated using grading scales. RESULTS: FDG uptake was visually recognized in all (100%) tumours. A homogeneous pattern of FDG uptake was increasingly observed in the order of low-risk thymomas to high-risk thymomas to thymic carcinomas (P = 0.016). SUVmax for thymic carcinomas was significantly higher than that for thymomas (P = 0.008). With the optimal cut-off value of SUVmax of 5.6, the sensitivity, specificity and accuracy for diagnosing thymic carcinoma were 0.75, 0.80 and 0.79, respectively. Regarding the mean scoring of HIF-1, Glut-1 and VEGF, increasing trends were observed in the order of low-risk thymomas to high-risk thymomas to thymic carcinomas. Tumour size revealed a significant correlation with SUVmax (r = 0.60, P < 0.001), and the expression of HIF-1 showed a moderate association, but the expression of Glut-1 showed no correlation with SUVmax. Regarding correlations between the expression of the three markers, there were moderate associations between HIF-1 and Glut-1, and HIF-1 and VEGF, and a significant correlation between Glut-1 and VEGF (r = 0.60, P < 0.001). In type B1 thymoma, HIF-1 and Glut-1 were partly expressed in non-neoplastic immature lymphocytes. CONCLUSIONS: FDG-PET/CT should be performed in patients with tumours in the anterior mediastinum because the pattern of FDG uptake and SUVmax are useful in the differential diagnosis of thymic epithelial tumours. Furthermore, the expressions of HIF-1, Glut-1 and VEGF might be associated with malignancy of thymic epithelial tumours. In contrast, FDG uptake might be dependent on tumour size rather than Glut-1 overexpression."},"publication_date":"2013-05-14","publication_name":{"en":"European Journal of Cardio-Thoracic Surgery","ja":"European Journal of Cardio-Thoracic Surgery"},"volume":"44","number":"2","starting_page":"e105","ending_page":"e112","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1093/ejcts/ezt263"],"issn":["1873-734X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} line:5, {"insert":{"user_id":"5000020102","type":"published_papers","id":"50574369"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=251889","label":"url"}],"paper_title":{"en":"Proton MRSにおける脳内代謝物の横緩和時間について-定量化に関わる要因として-","ja":"Proton MRSにおける脳内代謝物の横緩和時間について-定量化に関わる要因として-"},"authors":{"en":[{"name":"Harada Masafumi"},{"name":"Miyoshi Hirokazu"},{"name":"Otsuka Hideki"},{"name":"田岡 良章"},{"name":"Nishitani Hiromu"}],"ja":[{"name":"原田 雅史"},{"name":"三好 弘一"},{"name":"大塚 秀樹"},{"name":"田岡 良章"},{"name":"西谷 弘"}]},"publication_date":"1997-07","publication_name":{"en":"Nippon Acta Radiologica","ja":"日本医学放射線学会雑誌"},"volume":"57","number":"6","starting_page":"350","ending_page":"352","languages":["jpn"],"referee":true,"identifiers":{"issn":["0048-0428"]},"published_paper_type":"scientific_journal"},"priority":"input_data"} ==== end registerFile(/WWW/pub2/data/ERD/person/60298/researchmap/published_papers-propagate.jsonl, PU2NeqEBn_HdSsNVh317) ==== ==== begin registerFile(/WWW/pub2/data/ERD/person/60298/researchmap/presentations-propagate.jsonl) ==== line:1, {"insert":{"user_id":"5000020102","type":"presentations","id":"50574397"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=314344","label":"url"}],"presentation_title":{"en":"Proposal of an appropriate echo time-input function for quantitative susceptibility mapping.","ja":"Proposal of an appropriate echo time-input function for quantitative susceptibility mapping."},"presenters":{"en":[{"name":"Matsumoto Yuki"},{"name":"Kanazawa Yuki"},{"name":"Ikemitsu Nattsuki"},{"name":"Sasaki Toshiaki"},{"name":"Hayashi Hiroaki"},{"name":"Miyosh Mitsuharu"},{"name":"Harada Masafumi"},{"name":"Otsuka Hideki"}],"ja":[{"name":"松元 友暉"},{"name":"金澤 裕樹"},{"name":"Ikemitsu Nattsuki"},{"name":"Sasaki Toshiaki"},{"name":"林 裕晃"},{"name":"Miyosh Mitsuharu"},{"name":"原田 雅史"},{"name":"大塚 秀樹"}]},"event":{"en":"International Conference On Medical Physics (ICMP) 2016","ja":"International Conference On Medical Physics (ICMP) 2016"},"publication_date":"2016-12","languages":["eng"],"location":{"en":"Bangkok","ja":"Bangkok"},"description":{"en":"Purpose To improve the quantitative assessment for both diamagnetic and paramagnetic materials, we developed a quantitative susceptibility mapping (QSM) method using an appropriate echo time (TE)-input function. Methods On 3.0 T MR system, we performed a phantom experiment using a multi-echo spoiled gradient-echo (12 echos; delta TE = 4.4 ms). The phantom consisted of gadopentetate dimeglumine (Gd-DTPA) and hydroxyapatite samples, which were made using three different concentrations of each material. After a multiple TE dataset was acquired, T2* values were calculated from the dataset. When a field map estimation was computed, the appropriate T2* value was used as TE-input function. Next, phase unwrapping and background removal were performed. Finally, the reconstruction of QSM was performed. Moreover, we compared susceptibility values derived from TE-input function and conventional methods. Results The mean T2* values of each Gd-DTPA and hydroxyapatite sample were 365 ± 74, 194 ± 9, 86 ± 3, 24 ± 2, 14 ± 1, and 11 ± 1 ms, respectively. Compared with the conventional method, the proposed TE-input function method indicated good positive linearity for the relationship between the Gd-DTPA concentration and susceptibility (slope = 0.26 ppm/mmol/L, R2 = 0.97, P = 0.11). Additionally, the proposed TE-input function method indicated good negative linearity for the relationship between the concentration and hydroxyapatite susceptibility (slope = -0.0019 ppm/mg/mL, R2 = 1.00, P = 0.02). Conclusions QSM with the TE-input function makes it possible to evaluate simultaneously diamagnetic and paramagnetic materials. e.g. Gd-DTPA and hydroxyapatite.","ja":"Purpose To improve the quantitative assessment for both diamagnetic and paramagnetic materials, we developed a quantitative susceptibility mapping (QSM) method using an appropriate echo time (TE)-input function. Methods On 3.0 T MR system, we performed a phantom experiment using a multi-echo spoiled gradient-echo (12 echos; delta TE = 4.4 ms). The phantom consisted of gadopentetate dimeglumine (Gd-DTPA) and hydroxyapatite samples, which were made using three different concentrations of each material. After a multiple TE dataset was acquired, T2* values were calculated from the dataset. When a field map estimation was computed, the appropriate T2* value was used as TE-input function. Next, phase unwrapping and background removal were performed. Finally, the reconstruction of QSM was performed. Moreover, we compared susceptibility values derived from TE-input function and conventional methods. Results The mean T2* values of each Gd-DTPA and hydroxyapatite sample were 365 ± 74, 194 ± 9, 86 ± 3, 24 ± 2, 14 ± 1, and 11 ± 1 ms, respectively. Compared with the conventional method, the proposed TE-input function method indicated good positive linearity for the relationship between the Gd-DTPA concentration and susceptibility (slope = 0.26 ppm/mmol/L, R2 = 0.97, P = 0.11). Additionally, the proposed TE-input function method indicated good negative linearity for the relationship between the concentration and hydroxyapatite susceptibility (slope = -0.0019 ppm/mg/mL, R2 = 1.00, P = 0.02). Conclusions QSM with the TE-input function makes it possible to evaluate simultaneously diamagnetic and paramagnetic materials. e.g. Gd-DTPA and hydroxyapatite."},"is_international_presentation":true},"priority":"input_data"} line:2, {"insert":{"user_id":"5000020102","type":"presentations","id":"50574433"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=398772","label":"url"}],"presentation_title":{"en":"Multi-modality Imaging for the Patients with Metastatic Brain Tumors After Stereotactic Irradiation","ja":"Multi-modality Imaging for the Patients with Metastatic Brain Tumors After Stereotactic Irradiation"},"presenters":{"en":[{"name":"Hiroshima Yuka"},{"name":"Shinya Takayoshi"},{"name":"Ikushima Hitoshi"},{"name":"Otomi Youichi"},{"name":"Otsuka Hideki"},{"name":"Tonoiso Chisato"},{"name":"Kubo Akiko"},{"name":"Kawanaka Takashi"},{"name":"Takagi Yasushi"},{"name":"Harada Masafumi"}],"ja":[{"name":"廣島 由夏"},{"name":"新家 崇義"},{"name":"生島 仁史"},{"name":"音見 暢一"},{"name":"大塚 秀樹"},{"name":"外礒 千智"},{"name":"久保 亜貴子"},{"name":"川中 崇"},{"name":"髙木 康志"},{"name":"原田 雅史"}]},"event":{"en":"The 82nd Annual Meeting of the Japan Radiological Society","ja":"The 82nd Annual Meeting of the Japan Radiological Society"},"publication_date":"2023-04-13","languages":["eng"],"is_international_presentation":false},"priority":"input_data"} line:3, {"insert":{"user_id":"5000020102","type":"presentations","id":"50574440"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=390646","label":"url"}],"presentation_title":{"en":"肝内胆管癌との鑑別に苦慮した悪性リンパ腫の一例","ja":"肝内胆管癌との鑑別に苦慮した悪性リンパ腫の一例"},"presenters":{"en":[{"name":"saya matsuzaki"},{"name":"Shinya Takayoshi"},{"name":"岡田 直子"},{"name":"ryota mitsuhashi"},{"name":"Takaoka Yukiko"},{"name":"Otomi Youichi"},{"name":"Kubo Michiko"},{"name":"Matsumoto Yuki"},{"name":"Otsuka Hideki"},{"name":"Bando Yoshimi"},{"name":"Tsuneyama Koichi"},{"name":"Harada Masafumi"}],"ja":[{"name":"松崎 紗弥"},{"name":"新家 崇義"},{"name":"岡田 直子"},{"name":"三橋 遼太"},{"name":"高岡 友紀子"},{"name":"音見 暢一"},{"name":"久保 典子"},{"name":"松元 友暉"},{"name":"大塚 秀樹"},{"name":"坂東 良美"},{"name":"常山 幸一"},{"name":"原田 雅史"}]},"event":{"en":"第135回日本医学放射線学会中国・四国地方会","ja":"第135回日本医学放射線学会中国・四国地方会"},"publication_date":"2021-12-17","languages":["jpn"],"is_international_presentation":false},"priority":"input_data"} line:4, {"insert":{"user_id":"5000020102","type":"presentations","id":"50574460"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=321628","label":"url"}],"presentation_title":{"en":"動物PET計測において遮蔽体が散乱係数に与える影響","ja":"動物PET計測において遮蔽体が散乱係数に与える影響"},"presenters":{"en":[{"name":"Otani Tamaki"},{"name":"Otsuka Hideki"},{"name":"Miyoshi Hirokazu"},{"name":"Kuwahara Yoshinori"},{"name":"Irikura Namiko"}],"ja":[{"name":"大谷 環樹"},{"name":"大塚 秀樹"},{"name":"三好 弘一"},{"name":"桑原 義典"},{"name":"入倉 奈美子"}]},"event":{"en":"日本放射線安全管理学会第15回学術大会(岡山大学)","ja":"日本放射線安全管理学会第15回学術大会(岡山大学)"},"publication_date":"2016-12-01","languages":["jpn"],"promoter":{"en":"Japanese Society of Radiation Safety Management","ja":"日本放射線安全管理学会"},"is_international_presentation":false},"priority":"input_data"} line:5, {"insert":{"user_id":"5000020102","type":"presentations","id":"50574462"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=314345","label":"url"}],"presentation_title":{"en":"Noise estimation of phantom phase image in ultra-short echo time imaging","ja":"Noise estimation of phantom phase image in ultra-short echo time imaging"},"presenters":{"en":[{"name":"Matsumoto Yuki"},{"name":"Kanazawa Yuki"},{"name":"Ikemitsu Nattsuki"},{"name":"Sasaki Toshiaki"},{"name":"Hayashi Hiroaki"},{"name":"Miyosh Mitsuharu"},{"name":"Harada Masafumi"},{"name":"Otsuka Hideki"}],"ja":[{"name":"松元 友暉"},{"name":"金澤 裕樹"},{"name":"Ikemitsu Nattsuki"},{"name":"Sasaki Toshiaki"},{"name":"林 裕晃"},{"name":"Miyosh Mitsuharu"},{"name":"原田 雅史"},{"name":"大塚 秀樹"}]},"event":{"en":"JSMRM2016","ja":"JSMRM2016"},"publication_date":"2016-09-10","languages":["eng"],"location":{"en":"Saitama","ja":"Saitama"},"description":{"en":"Purpose: To estimate accurately noise of phase rotation, we evaluated a signal phase of ultra-short echo time (UTE) imaging. Materials and Methods: On 3.0T MR system, we performed a phantom experiment using a dual-echo UTE imaging. The imaging parameters were TE, 0.032 ms (first-echo) and 3.3 ms (second-echo); matrix sizes, 256 ×256; slice, 16. The phantom consisted of Gd-DTPA and hydroxyapatite samples, which were made using three different concentrations of each material; Gd-DTPA, 0.5, 1.0, and 2.5 mmol/L; hydroxyapatite, 100, 200, and 350 mg/mL. Then, region of interest analysis was performed on two phase images, e.g., first-echo, and second-echo phase images. Results: The mean first-echo phase values on each Gd-DTPA (0.5, 1.0, and 2.5 mmol/L) and hydroxyapatite (100, 200, and 350 mg/mL) sample were 32.4 ± 0.04, 32.2 ± 0.04, 32.0 ±0.01, 32.4 ± 0.02, 43.6 ± 0.03, and 60.0 ± 0.01 degree, respectively. The mean second-echo phase values on each Gd-DTPA (0.5, 1.0, and 2.5 mmol/L) and hydroxyapatite (100, 200, and 350 mg/mL) sample were 39.1 ± 0.04, 36.0 ± 0.04, 35.5 ± 0.05, 137.9 ± 0.06, 83.4 ± 0.06, and 88.02 ± 0.06 degree, respectively. The mean background phase value first-echo, and second-echo were 33.5 ± 0.11 and 87.1 ± 0.12 degree, respectively. Discussion & Conclusion: The phase rotation of hydroxyapatite occurred difference of phase value in each sample, i.e., this leads good contrast in UTE image. In contrast, the phase rotation of Gd-DTPA at TE 0.032 ms is small enough to estimate noise because the Gd-DTPA phase values were almost equal. Thus, UTE imaging may lead to noise derived from a phase rotation. Noise estimation using UTE imaging may render it possible to obtain more detailed information of paramagnetic materials, e.g., Gd-DTPA.","ja":"Purpose: To estimate accurately noise of phase rotation, we evaluated a signal phase of ultra-short echo time (UTE) imaging. Materials and Methods: On 3.0T MR system, we performed a phantom experiment using a dual-echo UTE imaging. The imaging parameters were TE, 0.032 ms (first-echo) and 3.3 ms (second-echo); matrix sizes, 256 ×256; slice, 16. The phantom consisted of Gd-DTPA and hydroxyapatite samples, which were made using three different concentrations of each material; Gd-DTPA, 0.5, 1.0, and 2.5 mmol/L; hydroxyapatite, 100, 200, and 350 mg/mL. Then, region of interest analysis was performed on two phase images, e.g., first-echo, and second-echo phase images. Results: The mean first-echo phase values on each Gd-DTPA (0.5, 1.0, and 2.5 mmol/L) and hydroxyapatite (100, 200, and 350 mg/mL) sample were 32.4 ± 0.04, 32.2 ± 0.04, 32.0 ±0.01, 32.4 ± 0.02, 43.6 ± 0.03, and 60.0 ± 0.01 degree, respectively. The mean second-echo phase values on each Gd-DTPA (0.5, 1.0, and 2.5 mmol/L) and hydroxyapatite (100, 200, and 350 mg/mL) sample were 39.1 ± 0.04, 36.0 ± 0.04, 35.5 ± 0.05, 137.9 ± 0.06, 83.4 ± 0.06, and 88.02 ± 0.06 degree, respectively. The mean background phase value first-echo, and second-echo were 33.5 ± 0.11 and 87.1 ± 0.12 degree, respectively. Discussion & Conclusion: The phase rotation of hydroxyapatite occurred difference of phase value in each sample, i.e., this leads good contrast in UTE image. In contrast, the phase rotation of Gd-DTPA at TE 0.032 ms is small enough to estimate noise because the Gd-DTPA phase values were almost equal. Thus, UTE imaging may lead to noise derived from a phase rotation. Noise estimation using UTE imaging may render it possible to obtain more detailed information of paramagnetic materials, e.g., Gd-DTPA."},"is_international_presentation":false},"priority":"input_data"} line:6, {"insert":{"user_id":"5000020102","type":"presentations","id":"50574470"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=273065","label":"url"}],"presentation_title":{"en":"PET/CTによるヒト肺癌細胞株肺移植モデルマウスの腫瘍評価","ja":"PET/CTによるヒト肺癌細胞株肺移植モデルマウスの腫瘍評価"},"presenters":{"en":[{"name":"Takizawa Hiromitsu"},{"name":"Kondo Kazuya"},{"name":"Otani Tamaki"},{"name":"Otsuka Hideki"},{"name":"Tsuboi Mitsuhiro"},{"name":"Kajiura Koichiro"},{"name":"Nakagawa Yasushi"},{"name":"Yoshida Mitsuteru"},{"name":"Kawakami Yukikiyo"},{"name":"Sakiyama Shoji"},{"name":"Tangoku Akira"}],"ja":[{"name":"滝沢 宏光"},{"name":"近藤 和也"},{"name":"大谷 環樹"},{"name":"大塚 秀樹"},{"name":"坪井 光弘"},{"name":"梶浦 耕一郎"},{"name":"中川 靖士"},{"name":"吉田 光輝"},{"name":"川上 行奎"},{"name":"先山 正二"},{"name":"丹黒 章"}]},"event":{"en":"第54回日本肺癌学会総会","ja":"第54回日本肺癌学会総会"},"publication_date":"2013-11-21","languages":["jpn"],"is_international_presentation":false},"priority":"input_data"} line:7, {"insert":{"user_id":"5000020102","type":"presentations","id":"50574480"},"force":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=235831","label":"url"}],"presentation_title":{"en":"TIA症例に対するDWI所見の検討","ja":"TIA症例に対するDWI所見の検討"},"presenters":{"en":[{"name":"Morita Naomi"},{"name":"Otsuka Hideki"},{"name":"Harada Masafumi"},{"name":"Satomi Junichiro"},{"name":"Nagahiro Shinji"},{"name":"Terasawa Yuka"},{"name":"Kaji Ryuji"}],"ja":[{"name":"森田 奈緒美"},{"name":"大塚 秀樹"},{"name":"原田 雅史"},{"name":"里見 淳一郎"},{"name":"永廣 信治"},{"name":"寺澤 由佳"},{"name":"梶 龍兒"}]},"event":{"en":"Journal of Japan Radiological Society","ja":"日本医学放射線学会学術集会抄録集"},"publication_date":"2010-10","languages":["jpn"],"is_international_presentation":false},"priority":"input_data"} ==== end 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