A critical role for thymic stromal lymphopoietin in nickel-induced allergy in mice.

Ni is the most frequent cause of contact allergy induced by metals. However, the underlying mechanism of this induction is unknown. Our previous research demonstrates that activation of dendritic cells (DCs) through p38MAPK/MKK6 is required for Ni-induced allergy in mice. In the current study, we investigated the cellular and molecular mechanisms underlying Ni-induced allergy using a mouse model that involves injecting Ni into the ear, with or without Freund's incomplete or complete adjuvants. Nickel had greater potential to cause allergic reactions compared with palladium and gold. Among the proteins expressed at higher levels in mice with Ni-induced allergy, we focused on thymic stromal lymphopoietin (TSLP), which is produced in abundance by keratinocytes. We detected increased expression of the TSLP receptor (TSLPR) in DCs from cervical lymph nodes of mice with Ni-induced allergy, suggesting that DCs in ear tissues were activated through TSLPR signaling induced by keratinocyte-derived TSLP. Furthermore, delayed-type hypersensitivity reactions in mice with Ni-induced allergy were decreased significantly by injection of a Tslp-short interfering RNA along with atelocollagen in the ear skin. These results suggest that Ni allergy may be triggered by a TSLP/TSLPR-mediated interaction between epithelial and immune cells.


Effects of extracellular DNA from Candida albicans and pneumonia-related pathogens on Candida biofilm formation and hyphal transformation.

The aim of this study was to investigate the effects of genomic DNA purified from Candida albicans and pneumonia-related pathogens, Pseudomonas aeruginosa and Staphylococcus aureus, on in vitro biofilm formation and morphological change of 3 Candida species (C. albicans, C. glabrata, and C. tropicalis). Biofilm formation was evaluated by the crystal violet assay and colony-forming unit counts. Morphological characteristics of biofilms were evaluated by scanning electron microscopy and fluorescence microscopy. Addition of DNA at a low concentration (<1·0 μg ml(-1)) significantly increased biofilm mass of all three Candida species. In contrast, the addition of DNA at a high concentration (10 μg ml(-1)) decreased the biofilm mass. Interestingly, the formation of hyphae in a dense network of yeast cells was observed in C. albicans biofilms exposed to a low concentration of DNA (<1·0 μg ml(-1)). These findings demonstrated that extracellular DNA (eDNA) plays a crucial role in Candida biofilm formation and suggested that eDNA may induce the morphological transition from yeast to hyphal growth form during C. albicans biofilm development. A novel therapy targeting eDNA may be applicable for Candida infection to decrease biofilm formation and hyphal formation.


The effect of simvastatin-loaded polymeric microspheres in a critical size bone defect in the rabbit calvaria.

The present study describes the development of a microsphere capsule based on polylactide-co-glycolide (PLGA) loaded with simvastatin that was subsequently incorporated into synthetic bone cement. The osteogenic effect of simvastatin-loaded bone cement was in a critical sized defect in vivo to test the hypothesis the biologic response would be different depending on the dosage of simvastatin applied to bone cement. Our results showed that simvastatin loaded PLGA microspheres can be successfully obtained through O/W emulsion/solvent evaporation method with appropriate morphologic characteristics and high encapsulation efficiency for incorporation in bone cements. The biodegradable characteristic of the microspheres successfully presented a slow release and the duration of the release lasted for more than 1 month. The in vivo experiment revealed that the microspheres containing simvastatin significantly enhanced bone formation in the rabbit calvaria critical size defect.


Blue-violet laser modification of titania treated titanium: antibacterial and osteo-inductive effects

Many studies on surface modifications of titanium have been performed in an attempt to accelerate osseointegration. Recently, anatase titanium dioxide has been found to act as a photocatalyst that expresses antibiotic properties and exhibits hydrophilicity after ultraviolet exposure. A blue-violet semiconductor laser (BV-LD) has been developed as near-ultraviolet light. The purpose of this study was to investigate the effects of exposure to this BV-LD on surface modifications of titanium with the goal of enhancing osteoconductive and antibacterial properties. The surfaces of pure commercial titanium were polished with #800 waterproof polishing papers and were treated with anatase titania solution. Specimens were exposed using BV-LD (λ = 405 nm) or an ultraviolet light-emitting diode (UV-LED, λ = 365 nm) at 6 mW/cm(2) for 3 h. The surface modification was evaluated physically and biologically using the following parameters or tests: surface roughness, surface temperature during exposure, X-ray diffraction (XRD) analysis, contact angle, methylene blue degradation tests, adherence of Porphyromonas gingivalis, osteoblast and fibroblast proliferation, and histological examination after implantation in rats. No significant changes were found in the surface roughness or XRD profiles after exposure. BV-LD exposure did not raise the surface temperature of titanium. The contact angle was significantly decreased, and methylene blue was significantly degraded. The number of attached P. gingivalis organisms was significantly reduced after BV-LD exposure compared to that in the no exposure group. New bone was observed around exposed specimens in the histological evaluation, and both the bone-to-specimen contact ratio and the new bone area increased significantly in exposed groups. This study suggested that exposure of titanium to BV-LD can enhance the osteoconductivity of the titanium surface and induce antibacterial properties, similar to the properties observed following exposure to UV-LED.


Should Occlusal Pressure be Applied in Fixing Magnet Assenmlies to Denture? An Evaluation using the Delphi Technique

The Journal of the Japanese Sociaty of Magnetic Applications in Dentistry


Long-term follow-up case reports on the use of magnetic attachment as intracoronal/extracoronal attachments


Stress Analysis of Magnet-Retained Mini-Implant Overdenture:InVitro Study

磁性アタッチメントを用いたミニインプラントオーバーデンチャーにおける力学的解析

The purpose of this study was to evaluate stress analysis of a magnet-retained mini-implant overdenture on an in vitro mandibular model. Mini implants less than 3.0 mm in diameter have been used as not only provisional use, but also permanent use to support overdentures.
Four mini implants (MagDen Fixture MFI4010RF, Shinwon Dental, Seoul, Korea) were placed in edentulous regions between bilateral canines in an acrylic resin mandibular model and the abutments (MagDen Keeper MFK4020, Shinwon Dental, Seoul, Korea) for magnet attachments were used. Seven strain gauges were attached on the resin surface around the right side of two mini implants. The surface of the model was covered with silicone impression material to simulate oral mucosa and an experimental complete denture was placed on the model. A vertical force of 50 N was applied to either one of the premolar, first molar and second molar of the experimental denture using a universal testing machine.
When four mini implants were supported, compressive strains were caused at the lingual side of the distal mini implant. The more posterior the loading point was, the lower the strain around the implant was generally. Although tensile strain was caused at the buccal side of the mesial mini implant, it decreased at the moment when compressive strain arose. When four implants were supported, the strain around the mini implants was distributed more evenly than those in the two implant-supported ones. The influence of implant positioning was examined by removing either two mesial or two distal attachments in the four mini implants. The maximum strain in two mesial implant-supported attachments was smaller than that in two distal implant-supported attachments.

Journal of Japanese Society of Oral Implantology

日本口腔インプラント学会誌


In Vitro Efficacy of Electrolyzed Dilute Sodium Hypochlorite Solution on Candidal Biofilm

In vitroカンジダバイオフィルムに対する電解次亜水の効果

The effectiveness of oral care interventions for preventing aspiration pneumonia and barriers to compromised elderly is universally-recognized in present medical practice. Quick and effective methods and materials are needed for oral health care. An electrolyzed dilute sodium hypochlorite solution was chosen as a sterilizing solution for oral health care and the sterilizing effect was evaluated using an in vitro candida biofilm. Three electrolyzed functional waters, namely strongly alkaline water, weakly acidic water, dilute sodium hypochlorite solution, two kinds of commercial mouth wash and distilled water were used as test solutions. Antibiofilm efficacy and residual chlorine concentration were evaluated before/after immersing candidal biofilm specimens in each solution. pH changes of the solutions and macroscopic observations of metal surface were evaluated before/after immersing three kinds of dental metals: steel bar, cobalt-chromium alloy and gold-silver-palladium alloy in the solutions to test the corrosion behavior. An electrolyzed dilute sodium hypochlorite solution showed high bactericidal capability of candida biofilm on cell desks and stable concentration of available chlorine, but high induction of metal corrosion.

口腔ケアは，要介護高齢者などの誤嚥性肺炎の予防など易感染性宿主に対する感染症予防において，医療現場で高く認知されている．効果的な口腔ケアをするにあたって適切な洗浄剤や清掃材料が求められる．本研究は，強力な殺菌効果が期待される電解次亜水に着目し，そのカンジダバイオフィルムに対する洗浄効果の評価法を用いて，その有効性と可能性について検討した． 試験液として，強アルカリ性電解水，弱酸性電解水，電解次亜水，2種類の市販の洗口液，滅菌蒸留水，計6種類を用いた．カンジダバイオフィルムを形成させた被着試料を用いて，各試験液の抗バイオフィルム効果およびバイオフィルム浸漬前後の有効塩素濃度の変化を検討した．歯科用金属に対する腐食性を検討するために，スチールバー，歯科用コバルトクロム合金，金銀パラジウム合金，計3種類の歯科用金属を用いて，試験液浸漬前後の pH の変化を測定した．また，試料表面の肉眼観察も行った． 電解次亜水は高いカンジダバイオフィルム殺菌・洗浄効果を認め，安定した有効塩素濃度が確保されたものの，金属腐食作用は強いことが示唆された．


Analysis of Small GTPases in Dendritic Cells and Keratinocytes in Nickel Allergy Mouse Model


Reliability and validity of diagnostic nomenclature system of prosthetic dentistry

補綴歯科治療病名システムの信頼性と妥当性の検討

Purpose: The Japan Prosthodontic Society (a public interest incorporated association) proposed a new diagnostic nomenclature system method that is based on pathogenesis and etiology for providing adequate prosthodontic treatment to patients. This diagnostic nomenclature system is based on "factor" and "disability", and assumes that a disability is caused by a factor. The aim of this study was to analyze the reliability and validity of several dentists' diagnoses on mock patient charts.Methods: The Clinical Guideline Committee of the Japan Prosthodontic Society made mock patient charts and decided the disease name with the new diagnosis system. Fifty evaluators (prosthodontic specialists and hospital residents) answered the disease name with the new diagnosis system. The reliability and validity of the diagnoses were analyzed.Results: Krippendorff's α, which evaluates the reliability, was 0.378 (prosthodontic specialists) and 0.401 (hospital residents). The value was 0.524 with the top 10 evaluators, and 0.628 with the top 2 evaluators. There was no difference between the prosthodontic specialists and hospital residents in the correct answer rate. The correct answer rate for common dental diseases was high and that for uncommon dental diseases was low. Moreover, there was no relation between the correct answer rate and answering time or years of experience.Conclusion: The reliability of the answers among all evaluators was not high, but it was high among the evaluators who showed a high correct answer rate in this study. The correct answer rate for common dental diseases was high and that for uncommon dental diseases was low.

目的:(社)日本補綴歯科学会は病態とその発現機序の把握に基づく適切な補綴歯科治療を国民に提供するために，補綴歯科治療における新たな病名システムを提案した．これは患者に生じている「障害」を病名の基本とし，この障害を引き起こしている「要因」を併記して病名システムとするものであり，「A(要因)によるB(障害)」を病名システムの基本的な表現法としている．本研究の目的は考案した方法に従って決定した補綴歯科治療における病名の信頼性と妥当性を検討することである．方法:模擬患者カルテを作成し，(社)日本補綴歯科学会診療ガイドライン委員会で模範解答としての病名(以下，模範病名)を決定した．その後，合計50 名の評価者(日本補綴歯科学会専門医(以下，補綴歯科専門医)ならびに大学病院研修歯科医(以下，研修医))に診断をしてもらい，評価者間における病名の一致度(信頼性)ならびに(社)日本補綴歯科学会診療ガイドライン委員会による模範病名との一致度(妥当性)を検討した．結果:評価者間の一致度を検討するための算出したKrippendorff's αは全体では0.378，補綴歯科専門医では0.370，研修医では0.401 であった．Krippendorff's αは模範病名との一致度の高い上位10 名の評価者(補綴歯科専門医:3 名，研修医:7 名)では0.524，上位2 名の評価者(補綴歯科専門医:1 名，研修医:1 名)では0.648 と上昇した．日常的に頻繁に遭遇する病名に関しては模範病名との一致度が高かったが，日常的に遭遇しない病名は模範病名との一致度は低い状況であった．さらに，模範病名との一致度とアンケート回答時間や診療経験年数の関連性を検討したところ，相関関係はみられなかった．結論:全評価者間の一致度を指標とした本病名システムの信頼性は高くはなかったが，模範病名との一致度の高い評価者間では一致度が高かった．日常的に遭遇する補綴関連病名については模範病名との一致度が高かった．以上から(公社)日本補綴歯科学会の新しい病名システムは臨床上十分な信頼性と妥当性を有することが示唆された．


Oral factors affecting titanium elution and corrosion: an in vitro study using simulated body fluid.

Ti, which is biocompatible and resistant to corrosion, is widely used for dental implants, particularly in patients allergic to other materials. However, numerous studies have reported on Ti allergy and the in vitro corrosion of Ti. This study investigated the conditions that promote the elution of Ti ions from Ti implants. Specimens of commercially pure Ti, pure nickel, a magnetic alloy, and a gold alloy were tested. Each specimen was immersed in a simulated body fluid (SBF) whose pH value was controlled (2.0, 3.0, 5.0, 7.4, and 9.0) using either hydrochloric or lactic acid. The parameters investigated were the following: duration of immersion, pH of the SBF, contact with a dissimilar metal, and mechanical stimulus. The amounts of Ti ions eluted were measured using a polarized Zeeman atomic absorption spectrophotometer. Eluted Ti ions were detected after 24 h (pH of 2.0 and 3.0) and after 48 h (pH of 9.0). However, even after 4 weeks, eluted Ti ions were not detected in SBF solutions with pH values of 5.0 and 7.4. Ti elution was affected by immersion time, pH, acid type, mechanical stimulus, and contact with a dissimilar metal. Elution of Ti ions in a Candida albicans culture medium was observed after 72 h. Elution of Ti ions in the SBF was influenced by its pH and by crevice corrosion. The results of this study elucidate the conditions that lead to the elution of Ti ions in humans, which results in implant corrosion and Ti allergy.


A Literature Review on the Perception of Implants : Comparison with Natural Teeth

インプラントの感覚能に関する文献的考察 天然歯との比較

日本口腔インプラント学会誌


Formability and mechanical properties of porous titanium produced by a moldless process

Tailor-made porous titanium implants show great promise in both orthopedic and dental applications. However, traditional powder metallurgical processes require a high-cost mold, making them economically unviable for producing unique devices. In this study, a mixture of titanium powder and an inlay wax binder was developed for moldless forming and sintering. The formability of the mixture, the dimensional changes after sintering, and the physical and mechanical properties of the sintered porous titanium were evaluated. A 90:10 wt % mixture of Ti powder and wax binder was created manually at 70°C. After debindering, the specimen was sintered in Ar at 1100°C without any mold for 1, 5, and 10 h. The shrinkage, porosity, absorption ratio, bending and compressive strength, and elastic modulus were measured. The bending strength (135-356 MPa), compression strength (178-1226 MPa), and elastic modulus (24-54 GPa) increased with sintering time; the shrinkage also increased, whereas the porosity (from 37.1 to 29.7%) and absorption ratio decreased. The high formability of the binder/metal powder mixture presents a clear advantage for fabricating tailor-made bone and hard tissue substitution units. Moreover, the sintered compacts showed high strength and an elastic modulus comparable to that of cortical bone.

Journal of Biomedical Materials Research. Part B, Applied Biomaterials


磁性アッタチメントを用いたミニインプラントオーバーデンチャーの力学的解析

磁性アッタチメントを用いたミニインプラントオーバーデンチャーの力学的解析

日本口腔インプラント学会誌


A Multi-Centered Epidemiological Study Evaluating the Reliability of the Treatment Difficulty Indices Developed by the Japan Prosthodontic Sociaty

補綴治療の難易度を測定するプロトコルの信頼性の検討 -(社)日本補綴歯科学会による多施設臨床研究-


Recording of individual identification information on dental prostheses using fluorescent material and ultraviolet light

The placement of individual identification on a prosthesis is very important for forensic dentistry and traceability. This article describes the unique naming/labeling of dentures with information for individual identification using a method in which information is invisible under natural light but visible under ultraviolet light-emitting diode/black light exposure. The use of laser beam machining with this method will enable the recording of a large amount of information.

The International Journal of Prosthodontics


固定方法からみたインプラント上部構造の臨床的・文献的考察

固定方法からみたインプラント上部構造の臨床的・文献的考察

As the connection mechanism between the superstructure and implant, the cement-retained type and screw-retained type are mainly used. The choice of a screw-retained versus a cement-retained superstructure is a complex and comprehensive decision involving many points of consideration. On the other hand, various retained methods that is complementary with each retained type have been proposed. In this article, various retained types which have been reported in the literatures and developed by us, were systematically assorted from the standpoints of retreivability, and the advantages were pointed out showing case photographs. This systematical information would help the selection of retained type of the superstructure.


Main occluding area in partially edentulous patients: changes before and after implant treatment

The 'main occluding area', the location where food crushing occurs during the first stroke of mastication, is reported to be an important concept; however, it is currently limited to findings in individuals with normal dentition. The purpose of this study was to assess the changes in the location, area and bite force of the main occluding area before and after implant treatments. We enrolled 50 partially edentulous and 22 normally dentate subjects. To identify the location of the main occluding area, each subject was instructed to freely bite once on a dental stopping using the partially edentulous side or the normally dentate area. The location, occluding contact area and bite force of the main occluding area before and after the implant treatments were analysed. The main occluding area was located at a reproducible location in the partially edentulous and normally dentate subjects. This location was principally the first molar region, and for the partially edentulous patients with missing teeth in the molar regions, it moved from the premolar region to the first molar region after treatment. The occluding contact area and bite force for the main occluding area increased (P < 0·05) after the implant treatment in the partially edentulous patients with missing teeth in the molar regions. These results suggest that the main occluding area can be restored to the first molar region after implant treatment and may be an important factor in the assessment of prosthodontic treatment.


The Survey on a General Youth's Eating Behavior

一般青年の食行動についての実態調査

Journal of Japanese Society for Mastication Science and Health Promotion


Biofilm formation of Candida albicans on implant overdenture materials and its removal.

The purposes of this study were to clarify the surface characteristics of various implant overdenture materials and the capabilities of Candida albicans adherence and biofilm formation on these surfaces, and to investigate the role of salivary mucin in biofilm formation. Seven commonly used implant and restorative materials were assessed. The surface roughness averages of all materials were limited to 0.07-0.10μm. Contact angles and salivary mucin absorption were measured. After 90-min initial adhesion and 2-day biofilm formation, the amounts of C. albicans were determined by counting colony-forming units and the morphological characteristics were observed by scanning electron microscopy (SEM). The effects of saliva coating and the influences of material surface property on initial adhesion, biofilm formation and its removability were analysed by univariate two-way analysis of variance and multiple linear regression analysis. Surface contact angle of materials, the index of hydrophobicity, was found to be correlated positively with initial adhesion and biofilm formation of C. albicans. A negative correlation between mucin absorption and removability of Candida biofilm indicates that mucin plays an important role in biofilm formation and its rigidity. SEM observation also revealed fewer Candida cells on saliva-coated Ti than on saliva-coated hydroxyapatite or acrylic resin. The materials with different hydrophobic property and compositions display diverse manners of salivary mucin absorption, initial adhesion and biofilm formation. The hydrophobic materials encourage enhanced initial adhesion, subsequently resulting in the active biofilm formation. Mucin has decisive effects on Candida immobilization and biofilm development on the materials. Surface hydrophilic property and composition of materials and salivary proteins, especially mucin, affect the process of Candida biofilm formation and influence the amount and rigidity of formed biofilm. The present data may be applied as a reference for selecting materials in implant overdenture treatment from a microbiological point of view.


MI sensor-aided screening system for assessing swallowing dysfunction: Application to the repetitive saliva-swallowing test

Assessment of swallowing dysfunction, particularly the risk of aspiration, is extremely important to clinicians because it provides crucial information for preventing morbidity and mortality from dysphagia. The purpose of this study was to describe a magneto-impedance sensor-aided screening system (MISS) for assessing swallowing function and clarify its effectiveness with the repetitive saliva-swallowing test (RSST). An MI sensor attached to the skin over the sternum detected the distance from a magnet attached to the skin over the thyroid cartilage during swallowing as the change of magnetic fields. The MISS was validated by videofluoroscopic and videoendoscopic observations. Further, the swallowing behavior of 93 individuals was assessed by using the MISS and then analyzed with the RSST. Swallowing behavior can be recorded and investigated objectively by signal inspection in the MISS compared with the conventional methods. The MISS is a simple and straightforward method for recording and safe because of dry swallow. The MISS system was validated by using simultaneous recordings with videofluoroscopic or videoendoscopic examinations, and compared with the conventional RSST method. The MISS combined with the RSST is an effective screening test for swallowing function.


Alternative Decision Making Considerations in Prosthodontics


Telescopic Magnetic Attachment for Implant-Supported Denture: Evaluation of Splint Effect

Retrievability, connecting strength, and ease of laboratory work are important but conflicting prerequisites for the success of an implant superstructure, particularly with regard to immediate function. To resolve this issue, a telescopic magnetic attachment system has been developed for implant-supported removable dentures. The splinting effect of the attachment was evaluated for stress distribution and elevation with an in vitro model of three implants in an edentulous mandible. Two types of telescopic magnetic attachments were prepared; the inclination angles of the axial wall of the abutment were 2.5 and 6.0 degrees. Three types of three-unit superstructures--a screw-retained superstructure and two telescopic magnet-retained superstructures--were fabricated. Static loads of 24.5, 49, and 98 N were applied vertically at three loading points on one side of each occlusal table. The elevation was measured as the height at which the magnet-retained superstructure detached from the abutment (on the other side of the prosthesis). In addition, by means of strain gauges, the stress distribution around the implants was evaluated and compared among the superstructures with the same three loads applied at six different points. The magnet-retained superstructure with the axial wall inclined at 2.5 degrees did not detach from the abutment. The differences in stress distribution between the screw-retained and magnet-retained superstructures with a 2.5-degree inclination were found to be statistically insignificant. The magnet-retained superstructure with a 6-degree inclination detached from the abutment, and the stress was concentrated during loading to a cantilever site. Because of its stress distribution and elevation, the new telescopic magnetic attachment, which has properties such as splinting the implants, ease of fabrication, and retrievability, is expected to be a viable alternative for the retention of implant-supported removable dentures.

The International Journal of Oral & Maxillofacial Implants


A Novel DC Therapy with Manipulation of MKK6 Gene on Nickel Allergy in Mice

BACKGROUND: Although the activation of dermal dendritic cells (DCs) or Langerhans cells (LCs) via p38 mitogen-activated protein kinase (MAPK) plays a crucial role in the pathogenesis of metal allergy, the in vivo molecular mechanisms have not been identified and a possible therapeutic strategy using the control of dermal DCs or LCs has not been established. In this study, we focused on dermal DCs to define the in vivo mechanisms of metal allergy pathogenesis in a mouse nickel (Ni) allergy model. The effects of DC therapy on Ni allergic responses were also investigated. METHODS AND FINDING: The activation of dermal DCs via p38 MAPK triggered a T cell-mediated allergic immune response in this model. In the MAPK signaling cascade in DCs, Ni potently phosphorylated MAP kinase kinase 6 (MKK6) following increased DC activation. Ni-stimulated DCs could prime T cell activation to induce Ni allergy. Interestingly, when MKK6 gene-transfected DCs were transferred into the model mice, a more pronounced allergic reaction was observed. In addition, injection of short interfering (si) RNA targeting the MKK6 gene protected against a hypersensitivity reaction after Ni immunization. The cooperative action between T cell activation and MKK6-mediated DC activation by Ni played an important role in the development of Ni allergy. CONCLUSIONS: DC activation by Ni played an important role in the development of Ni allergy. Manipulating the MKK6 gene in DCs may be a good therapeutic strategy for dermal Ni allergy.


Survival of immediate implant restoration: A retrospective study through 9-year-observation

The purpose of this retrospective study was to assess the implant survival rate and the risk factors associated with implant failure in patients who had undergone immediate implant restoration. We performed a retrospective review and an outcome assessment of all patients who received immediate implant restoration between 2000 and 2010 in our department at Tokushima University Hospital. The patients were divided into groups on the basis of the predictor variables: age, gender, implant location, and number of implants per jaw. The cumulative implant survival rate in the paired groups was determined by using Kaplan-Meier analysis and the log-rank test. Cox proportional hazards model was subsequently used to identify exposures associated with implant failure. Using the Kaplan-Meier method, the survival rates at 1, 3, and 9 years were calculated to be 98.8%, 98.0%, and 94.7%, respectively. No statistically significant association was observed between the implant survival rates and the predictor variables: gender, age, location, and number of implants. Immediate implant restoration is a reliable prosthetic procedure with an acceptable survival rate compared to the conventional implant procedure.


二酸化チタン塗布エナメル質への青紫色半導体レーザー照射の影響，漂白効果について

二酸化チタン塗布エナメル質への青紫色半導体レーザー照射の影響，漂白効果について


Devalopment and Evaluation of a Computer-assisted Navigation System Equipped with a Motion Sensor in Implant Dentistry

姿勢検出センサを用いたインプラント埋入ナビゲーションシステムの開発

本研究では，3次元的な角度変化を計測できる姿勢検出センサを用いて開発を行った簡易的なインプラント埋入ナビゲーションシステムを開発した．本稿では，本システムの概要について紹介する．また，インプラント埋入の経験のない歯科医師を対象として，外科用ガイドプレートと本ナビゲーションシステムを用いてインプラント窩の形成を行う実験の結果について報告し，本システムの有用性と将来性について述べる．

Journal of Japanese Society of Oral Implantology

日本口腔インプラント学会誌


Carbon dioxide laser application enhances the effect of silane primer on the shear bone strength between porcelain and composite resin

The purpose of this study was to evaluate the effect of carbon dioxide laser irradiation on the performance of silane coupling agent as an adhesion promoter. The carbon dioxide laser used in this study was Opelaser 03S II, which irradiated the silane coupling agent applied on the adhesive surface of porcelain. Before and after thermal cycling, shear bond strength was measured using a universal testing machine. Without primer treatment, most of the specimens failed adhesively before reaching the end of the thermal cycling period. For the specimens irradiated with carbon dioxide laser after primer treatment, their shear bond strengths before and after thermal cycling were higher than those treated with primer only -with a significantly pronounced difference between these two groups especially after thermal cycling. Therefore, a combined surface treatment which involved silane application followed by laser treatment was feasible and efficacious for chairside porcelain repair.


CO2レーザー照射が象牙質の耐酸性向上に与えるあたえる影響 -フッ化物との併用について-


Enhanced germicidal effects of pulsed UV-LED irradiation on biofilms.

This study can assist in developing a low-frequency pulsed UVA-LED system to be applied to pathogenic biofilms for disinfection.

The germicidal effects of UVA-LED irradiation (365 nm, 0·28 mW cm(-2) , in pulsed or continuous mode) on Candida albicans or Escherichia coli biofilms were evaluated by determining colony-forming units. The morphological change of microbial cells in biofilms was observed using scanning electron microscopy. After 5-min irradiation, over 90% of viable micro-organisms in biofilms had been killed, and pulsed irradiation (1-1000 Hz) had significantly greater germicidal ability than continuous irradiation. Pulsed irradiation (100 Hz, 60 min) almost completely killed micro-organisms in biofilm (>99·9%), and 20-min irradiation greatly damaged both microbial species. Interestingly, few hyphae were found in irradiated Candida biofilms. Moreover, mannitol treatment, a scavenger of hydroxyl radicals (OH(•) ), significantly protected viable micro-organisms in biofilms from UVA-LED irradiation.


New glass polyalkenoate temporary cement for cement-retained implant restoration: Evaluation of elevation and retentive strength

The purpose of this study was to evaluate four luting agents for cement-retained implant restorations in two aspects: post-cementation elevation of the superstructure and the retentive strength before and after thermocycling and mechanical cycling. The four evaluated luting agents were: new glass polyalkenoate hard-type (GH) and soft-type (GS) cements, polycarboxylate hard-type (HH) and soft-type (HS) cements. Elevation and retentive strength were measured using a CCD laser displacement sensor and a universal testing machine respectively. Elevation increased in this order: GH, GS, HH, and HS. Thermal and mechanical stresses significantly decreased retentive strength, and the mean values exhibited by GH were significantly higher than the other luting agents. The novel glass polyalkenoate cements (hard- and soft-type) experimentally prepared in the present study augured well as luting agents by virtue of their reduced film thickness and their excellent post-cementation retention and elevation.


スプリント療法ガイドラインの確立

スプリント療法ガイドラインの確立

Journal of the Japanese Association for Dental Science


A new method to prevent the corrosion of dental materials, during disinfection using functional water: Sacrificial protection

This paper demonstrates a simple method using sacrificial protection for preventing the corrosion of dental metals. Dental metals are directly connected or/and wound with a pure commercial aluminum/zinc wire/plate with high ionization tendency, before their immersion into oxidizing functional water. Dental materials such as Co-Cr alloy wires, stainless steel, and Au-Ag-Pd alloys did not corrode when this method was used. Thus, this method is very simple and effective for preventing corrosion of dental metals during disinfection using functional water.


磁石固定式上部構造におけるインプラント支持歯槽骨の光弾性応力解析

磁石固定式上部構造におけるインプラント支持歯槽骨の光弾性応力解析

The Journal of the Japanese Society of Magnetic Applications in Dentistry


顎関節症のスプリント治療に関する実態調査 大学病院顎関節症外来および一般開業歯科医院における診療時間の比較

Journal of the Japanese Society for the Temporomandibular Joint


Effect of substrate surface hydrophobicity on the adherence of yeast and hyphal Candida

A biofilm composed of various microorganisms including Candida is found on denture surfaces and is likely to be involved in the etiology of denture-induced stomatitis. The purpose of this study was to examine the role of hydrophobic interactions in candidal adherence to acrylic surfaces, particularly that of the hyphal form of Candida albicans. Candida clinical isolates were used. Acrylic plates coated with carrageenan and hydrocolloid (Hitachi chemical, Tokyo, Japan) were used as a hydrophilic substratum. A microbial suspension was placed on each acrylic plate and incubated. All plates were washed in phosphate-buffered saline containing CaCl(2) and MgCl(2) [PBS (+)] and cells still adhering to the acrylic surface were collected by 0.25% trypsin treatment. Cell-surface hydrophobicity was estimated using a modification of the technique used to measure adherence to hydrocarbons. When the acrylic plates were coated with hydrophilic materials, the adherence of hydrophobic clinical isolates of Candida and the hydrophobic hyphal C. albicans decreased, whereas the adherence of non-hydrophobic Candida was not affected or increased. We suggest that hydrophilic coating of denture surfaces could be a potent method for reduction of the adherence of relatively hydrophobic fungal cells, particularly hyphal C. albicans, which causes denture stomatitis and related infections.


Effects of heat treatment on the bioactivity of surface-modified titanium in calcium solution

The purpose of this study was to determine the effects of heat treatment on the bioactivity of hydrothermal-modified titanium in CaO solution for improved bioactivity by immersion in simulated body fluid (SBF). The hydrothermal treatment of titanium in CaO solution was performed at 121 degrees C at 0.2 MPa for 1 h in an autoclave followed by 1 h heat treatments at 200, 400, 600 and 800 degrees C simultaneously. The bioactivity of titanium was evaluated by hydroxyapatite precipitation during immersion in SBF. Surface microstructure changes after the heat treatments and immersion in SBF were determined by X-ray diffractometry (XRD), X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy (SEM). Heat treatments at high temperatures (600 and 800 degrees C) promoted the synthesis of anatase, increased the thickness of the titanium oxide layer on the modified titanium surface and promoted the synthesis of calcium titanate, which possibly promoted the precipitation of apatite in SBF. The extent of precipitations increased with the time of immersion in SBF and the temperature of the heat treatment. Island-like deposits of needle-like crystals were observed only on the surface of the 600 and 800 degrees C heat-treated specimens after two or four week immersions in SBF. The results suggested that treatments of the surface of hydrothermal-treated titanium specimens at high temperatures (600 and 800 degrees C) could be effective for the surface modification of titanium as an implant material offering better osseointegration.


Evaluation of Measurement Accuracy in Imaging Using a Cone-beam CT

小照射野歯科用CT撮影における画像測定精度の検討

Journal of Japanese Society of Oral Implantology

日本口腔インプラント学会誌


A new retrieval system for cement-retained implant superstructures.

This article discusses two methods for improving the retrievability of cement-retained implant superstructures. One method involves incorporating a removal screw in the superstructure and the second method uses a small dimple on the abutment, accessed through a vent in the superstructure.


Implant prostheses and adjacent tooth migration: preliminary retrospective survey using 3-dimensional occlusal analysis.

Occlusal force analysis was retrospectively evaluated to clarify the proximal contact loss after fixed implant prosthesis placement. Twenty-eight patients (55 prostheses) with fixed implant prostheses in the posterior region were divided into 2 groups: proximal contact loss and unchanged groups. The occlusal force and its distribution were 3-dimensionally measured using the Dental Prescale system. A high proportion of lingual and anterior component forces and high occlusal force distribution in the intercanine region were observed in the contact loss group. The high occlusal force of the adjacent tooth may enhance the mesial migration.

The International Journal of Prosthodontics


小照射野歯科用CT装置での患者被曝線量の検討．被曝測定用X線フィルムを用いた解析．

日本口腔インプラント学会誌


Methods for Computer-Aided Diagnosis of Mastication

コンピュータ支援による咀嚼運動診断のための解析方法

Our research group is developing a system for computer-aided diagnosis(CAD) of mastication, that is based on the hypothesis of the Craniomandibular Control System. In this article, we described methods how to analyze the movement of condyle in temporo-mandibular joint with CAD system, and how to use dynamic data for diagnosis. Result of our research suggested that the method visualizing and measuring the distance between points on the fossa and those on the condyle is useful to see dynamic charactaristics of the movement of condyle. Using these methods we can see the effects of the altered anterior guidance on working side condylar movements. To complete our CAD system, we have two technical challenge, the one is automatic segmentation of osseous components from data digitized copmputed tomography, and the other is innovation of reference face bow unit that sets coordinate system of jaw tracking device and that of morphorogical data together.

現在私たちの研究グループでは，顎機能制御系の仮説に基づいて，形態情報と運動を加えた咀嚼運動のCADシステム構築を目指している．本稿ではこのシステム構築のための顎関節の解析方法を示すとともに，診断への可能性を示す例として補綴装置が顎運動に及ぼす影響を提示した．骨関節隙を用いた顆頭運動評価は顎関節の微小な動きをダイナミックに表現でき，診断に有用と思われる．また，補綴装置の形態の違いによって顎関節の動きに変化が認められ，診断への応用が可能である．咀嚼運動のCADシステムが広く使用されるために克服すべき技術的課題として，CT画像における顎関節形態の自動認識，形態および顎運動の座標系統一のための冶具の改良が挙げられる．


Denture plaque microflora in geriatric inpatients and maxillary defect patients

Purpose: The purpose of this study was to investigate denture plaque microflora of geriatric inpatients and maxillary defect patients from the standpoint of infection control in the elderly.Methods: Denture plaque was collected from 80 elderly subjects who were categorized into 3 groups: group A, 21 healthy complete denture wearers; group B, 49 complete denture wearers residing at a geriatric hospital; and group C, 10 complete denture wearers with maxillary defects. The microflora was investigated by counting the total number of microorganisms, including streptococci, staphylococci, and Candida spp.Results: The colony-forming unit (CFUs) count and incidence, particularly those of Candida spp., were significantly higher in group B (P<0.01). The CFUs of staphylococci were significantly higher in group C (P<0.01), and methicillin-resistant Staphylococcus aureus (MRSA) was observed in all Staphylococcus-positive patients. The CFUs of Candida spp. were significantly correlated to those of staphylococci (P<0.01).Conclusion: A high CFU count of Candida spp. and staphylococci (including MRSA) are characteristic of the microflora in geriatric inpatients and maxillary defect patients, respectively. This study supports the hypothesis that dentures might serve as potential reservoirs of organisms causing systemic infections.


Improvement of Oral Condition of Elderly using Oral Rinse with Benzethonium Chloride

塩化ベンゼトニウム配合洗口液を用いた高齢者の口内環境の改善

日本補綴歯科学会雑誌. 特別号, 日本補綴歯科学会学術大会抄録集 = Proceedings of the ... conference, the Japan Prosthodontic Society


Evaluation of Patient Dose in Imaging Using a Cone-beam CT for Dental Use.

小照射野歯科用CT装置での患者被曝線量の検討

日本口腔インプラント学会誌


Evaluation of Factors Affecting the Value of a New Wireless Resonance

非接触型共鳴振動周波数分析装置の値に影響を与える因子についての検討

日本口腔インプラント学会誌


Influence of a Vent Hole on the Retentive Force of a Cement-retained Superstructure before/after Thermocycling

Purpose: The purpose of this study was to evaluate the influence of a vent hole on the retentive force of a cement-retained superstructure to an abutment.
Methods: The retentive force of superstructures with/without a vent hole, retained using one of two luting cements, was measured using a universal testing machine both before and after thermocycling
Results: The retentive force of the cement-retained superstructure with the vent hole was greater than that of the cement-retained superstructure without the vent hole. While the retentive force decreased significantly after thermocycling, the size of the vent hole had little influence on the retentive force.
Conclusion: It was concluded that placement of a vent hole in the superstructure is useful, with little adverse effect on the retentive force of the restoration.


Effect of surface treatment with commercial primers on tensile bone strength of auto-polymerizing resin to magnetic stainless steel

International Chinese Journal of Dentistry


日本補綴歯科学会でいまどうして症型分類なのか

日本補綴歯科学会でいまどうして症型分類なのか


In vitro Study of Stress Distribution on Additional Posterior Mandibular Implants

Purpose : This in vitro study investigated the influence of implant splinting on stress distribution in two experimental implant-bone models.Materials and Methods : Two experimental implant-bone models simulated the original Brånemark model with four implants between the mental foramina and one additional implant placed on each side posterior to the mental foramen. The stress distribution on each implant in the models was examined by applying a static load to the superstructure. Three types of superstructures were studied to determine the effect of additional implants in the posterior region : 1) a metal superstructure supported by all six implants (Full dental arch ; Metal FDA) ; 2) the same type of superstructure made of resin instead of metal (Resin FDA) ; and 3) the metal superstructure supported by four anterior implants, with the conical abutments removed from the two posterior implants (Short dental arch ; Metal SDA).Results : Regardless of the type of superstructure tested, high stress was observed around each loaded implant. The highest stress was concentrated on the distal implants of the FDA compared to the stress on the anterior implants.Conclusion : The elevated stress concentration around the implants found in the present in vitro study is considered to be one of the reasons for the high failure rate of additional posterior mandibular implants.


Extracellular matrix formed by MC3T3-E1 osteoblast-like cells cultured on titanium 2. Collagen fiber formation

Many aspects of the structures formed between titanium and cells and the mechanism of the formation are still unknown. In order to clarify these issues, we analyzed the initial structures formed between titanium and MC3T3-E1 osteoblast-like cells cultured on titanium. The present results indicate that extracellular matrix containing collagen fibers formed at the surface of a calcined layer on the titanium. At first, a hemispherical body and a small secondary spherical structure formed at the surface, followed by more beads to form a string-of-beads structure. These string-of-beads collagen structures elongated and formed spirals. For the first time ever, we directly observed the structure of collagen fiber formed between cultured osteoblasts and titanium with microscopy. Here, we describe the formation mechanism of type I collagen fibers in extracellular bone matrix. Elucidation of the mechanism of collagen fiber formation will aid in the development of controlled tissue regeneration.


Extracellular matrix formed by MC3T3-E1 osteoblast-like cells cultured on titanium 1. Anchor structure

In order to clarify the structure of the extracellular matrix formed by osteoblasts in contact with titanium, we analyzed the structure formed by cultured clonal MC3T3-E1 osteoblasts on a calcified surface of commercial pure titanium, after exfoliating the cells from the surface of the titanium. Collagen fibers formed between neighboring cells and between cells and titanium, in the latter case with one tip of each collagen fiber bound to the cell and the other tip bound to the surface of the titanium embedded in the calcified layer. We called this structure an "anchor structure", because the collagen fibers embedded in the calcified layer anchor the cells to the titanium. This structure may be a reason for the useful biocompatibility between titanium and bone.


より確かな機能回復を目指すための舌機能評価法の確立

より確かな機能回復を目指すための舌機能評価法の確立

Journal of the Japanese Association for Dental Science


レーザー溶接による磁性アタッチメントキーパーの取り付け法 --- 吸引力と腐蝕の検討

Purpose: Recently, laser welding has gained wide acceptance as a dental laboratory technique for bonding metals. We have previously reported a new technique for installing a magnetic keeper in the overdenture abutment coping using laser welding. In the present study, the influence of this technique on the attractive force and corrosion were evaluated.
Methods: A commercially-available magnetic keeper and dental casting Au-Ag-Pd alloy were used. Specimens were prepared by one of the following procedures: original magnetic keeper only, conventional cast-on technique and laser welding technique. Attractive force between thedental magnetic assembly and magnetic keeper was measured using a self-made measuring device. The results were analyzed using the one-way ANOVA test. The external and inner surface of magnetic keepers and cross sections of specimens were observed using metal and stereoscopic microscopes before and after immersion of the specimens in 0.9% NaCl solution for 21 days.
Results: There was no significant difference of attractive force between the conventional cast-on technique and laser welding technique. All of the specimens using the cast-on technique rusted in the corrosion test. Half of the specimens using the laser welding technique changed less, and no oxidized layer or corrosion was observed on the surface.
Conclusions: Installation of magnetic keepers using laser welding is useful for increasing both attractive force and corrosion resistance.

The Journal of the Japan Prosthodontic Society


スクリュー締め付け回転角/トルク計測によるインプラント上部構造の適合性評価

スクリュー締め付け回転角/トルク計測によるインプラント上部構造の適合性評価

Purpose: Misfit of superstructure-supported osseointegrated implants causes adverse stress in the prosthesis, components, and surrounding bone. A passive fit of the implant-supported prosthesis is essential for successful long-term osseointegration. Various clinical methods for evaluating the fit of implant-supported prostheses have been suggested. However, the methods have little scientific evidence to determine the acceptable fit. The present study evaluated the misfit of implant-supported prostheses by measuring the rotational angle/tightening torque in screwing the prosthesis on master models.
Materials and Methods: Twenty-four implant-supported prostheses (3 single standing, 20 fixed partial, 1 full bridge) of fourteen patients were evaluated using a custom-made rotational angle/ tightening torque measuring apparatus on the master models. The influence of the order of tightening and unit number on the value was also evaluated.
Results: The mean of the rotational angle/tightening torque was 2.6 (SD: 0.6) degree/Ncm in all prostheses. The value was significantly higher than that in the abutment screw as a control. The order of tightening and unit number did not significantly affect the values.
Conclusions: The results suggest that measurements of rotational angle/tightening torque be useful for evaluating the fit of implant-supported prostheses. Misfit of the prostheses was below the level of acceptable fit.


スクリュー締め付け回転角/トルク計測によるインプラント上部構造の適合性評価

スクリュー締め付け回転角/トルク計測によるインプラント上部構造の適合性評価


上顎全部床義歯の後縁設定に関する一考察

上顎全部床義歯の後縁設定に関する一考察


歯科医療における誤嚥の診断·予防およびその対策

歯科医療における誤嚥の診断·予防およびその対策


Influence of Changes in Occlusal Vertical Dimension on Tongue Pressure to Palate during Swallowing

Purpose : The purpose of the present study was to examine the relationship of tongue pressure and changes in occlusal vertical dimension to swallowing.Materials and Methods : The volunteer subjects were four young male dentulous adults and eight elderly complete denture wearers. The tongue pressure to the palate was simultaneously recorded with electromyography (EMG) measurements of the suprahyoid muscles as the occlusal vertical dimension changed. The subjects were instructed to perform two actions : swallowing without any liquid or food (dry swallowing) and swallowing of 2 ml water (wet swallowing).Results : During dry swallowing, the maximum pressure decreased significantly as the vertical dimension increased in the young subjects. In the elderly, the maximum tongue pressure decreased monotonically as the vertical occlusion increased. The same results were clearly found for wet swallowing. Overall data suggested that the tongue pressure of the elderly group was lower and the duration of tongue pressure in wet swallowing was longer than that of the younger group.Conclusion : An increase of the vertical dimension decreased the tongue pressure to the palate, whereas a decrease of the vertical dimension affected the tongue pressure less. Tongue pressure is an important factor for the evaluation of tongue function, especially swallowing.


Complete denture with a removable palatal lift prosthesis --- A case report and clinical evaluation

The palatal lift prosthesis is used to alleviate rhinopharyngeal closure dysfunction. It is generally problematical to use in edentulous patients, because the palatal lift prosthesis requires secure retention of the denture base and is difficult for the patient to retain while eating. This article describes the fabrication of a complete denture with a removable palatal lift prosthesis and a clinical evaluation of the denture's stability. A sprue pin and tube were used as a connecting attachment between the removable palatal lift prosthesis and the denture base. The force required for lifting the soft palate and the denture's stability were measured in the clinical evaluation. The prosthesis required an average retentive force of 0.26 N for each 1 mm of soft palate lift. The force required to dislodge the denture was measured with and without the palatal lift prosthesis in place. The force required to dislodge the conventional complete dentures of five healthy individuals was also measured as a reference. The denture was 24.4% less stable when the palatal lift prosthesis was in place and was generally easier to dislodge than were conventional dentures. This denture with a removable palatal lift prosthesis is useful for patients with dysfunction of the soft palate involving hypernasal speech who have difficulty in retaining the prosthesis while eating.


デンチャープラークと咽頭の微生物叢との関連性

デンチャープラークと咽頭の微生物叢との関連性

Purpose: Prevention of an infection, especially aspiration pneumonia, is an important theme in the elderly. We are pointing out risk that is causing an infection such as the aspiration pneumonia, and a denture acts as a reservoir of microorganisms. The aim of this study was to examine the relationship between denture plaque and pharyngeal microflora in the elderly, and the drug susceptibility of isolated Candida spp.
Methods: We collected samples of denture plaque and pharyngeal plaque from elderly patients in a geriatric hospital and Tokushima University Dental Hospital (TUDH). The microflora was investigated by the detection of oral streptococci, staphylococci, Candida spp., Pseudomonas aeruginosa, Escherichia coli and coliforms, and MRSA. Isolated Candida spp. were measured for drug susceptibility.
Results: The microflora of denture plaque was very similar to pharyngeal microflora. A higher incidence of most microorganisms was observed in the patients in TUDH compared with patients in the geriatric hospital. Staphylococci were detected from the patients who harbored Candida spp. All strains of Candida spp. appeared to be susceptible to amphotericin B. Some strains of C. glabrata, C.tropicalis, and C. krusei appeared to be less susceptible to fluconazole. Fluconazole-resistant C. albicans was not isolated.
Conclusions: Denture plaque strongly influences the pharyngeal microflora in the elderly.


Fracture mechanisms of retrieved titanium screw thread in dental implant

Titanium and its alloy are increasingly attracting attention for use as biomaterials. However, delayed fracture of titanium dental implants has been reported, and factors affecting the acceleration of corrosion and fatigue have to be determined. The fractured surface of a retrieved titanium screw and metallurgical structures of a dental implant system were analyzed. The outer surface of the retrieved screw had a structure different from that of the as-received screw. It was confirmed that a shear crack initiated at the root of the thread and propagated into the inner section of the screw. Gas chromatography revealed that the retrieved screw had absorbed a higher amount of hydrogen than the as-received sample. The grain structure of a titanium screw, immersed in a solution known to induce hydrogen absorption, showed features similar to those of the retrieved screw. It was concluded that titanium in a biological environment absorbs hydrogen and this may be the reason for delayed fracture of a titanium implant.


Shock Absorbability and Hardness of Commercially Available Denture Teeth

Composite resin teeth are more widely used than porcelain or acrylic resin teeth in the fabrication of removable dentures because of their high fracture toughness and high abrasion resistance. The purpose of this study was to evaluate the shock absorbability of commercially available artificial posterior teeth by the free drop-ball test with an accelerometer and to evaluate the Vickers hardness at the surface. The tested artificial teeth included seven composite resin teeth, one acrylic resin tooth, and one porcelain tooth. Specimens were tested 50 hours after immersion in distilled water at 37 degrees C. The impact value and Vickers hardness were measured. A one-way analysis of variance was used to analyzed the data (P = .05). The composite resin teeth showed an intermediate impact value between that of the acrylic resin tooth and the porcelain tooth. Among the artificial teeth investigated, the porcelain tooth showed the highest impact value. A significant difference in the impact value was observed between the porcelain tooth and the composite resin and acrylic resin teeth. However, no significant difference was observed among the composite resin teeth tested. A significant correlation was found between the impact values and the Vickers hardness of the artificial teeth. The present findings suggest that composite resin teeth and acrylic resin teeth have a higher shock absorbability than porcelain teeth.

The International Journal of Prosthodontics


Dynamics of bone marrow pressure with tapping of titanium and hydroxyapatite implants in rabbit

The purpose of the present study was to evaluate the difference in stress transfer between titanium (Ti) and hydroxyapatite (HA) by the measurement of bone marrow pressure using a catheter pressure transducer. Ti and HA implants were inserted in the tibiae of rabbits. A hole of 1 mm in diameter was drilled in the bone and a fine catheter pressure transducer was placed in the bone marrow through a tube. The top of the abutment was vertically tapped with an impulse hammer, and the acceleration signal from the hammer and pressure signal from the catheter pressure transducer were examined. The time of contact (impulse duration) recorded in the impulse with Ti and HA was 166+/-17 micro sec and 164 +/- 17 micro sec, respectively. Maximum bone marrow pressure (BMP) with Ti and HA was 54.2 +/- 32.6 and 47.5 +/- 10.0 mmHg, respectively. Variation of the BMP with Ti was significantly larger than that with HA (P < 0.05). A negative correlation coefficient between impulse duration and BMP was found. The results of the present study suggest that the stress transfer is different between Ti and HA implants using dynamics of the bone marrow pressure.


Influence of Screw Tightening on Stress Distribution around Implant:An in vitro Experiment --- 模型実験

インプラントのスクリュー締結が周囲組織に及ぼす影響 --- 模型実験

Screw tightening of the superstructure of osseointegrated implants often produces unsuitable strain on the prosthesis and surrounding bone The purpose of this study was to investigate the effects of screw tightening on surrounding bone in several conditions
 Three Steri-oss® implants were placed in an acrylic resin experimental model and a three-unit framework was fabricated on the implants The fit of the framework was judged excellent by laboratory microscopy Ten strain gauges were attached on the experimental model surface around the implants The strain was measured after every screw was tightened by a custom-designed torque controller Static and dynamic strain was recorded Each test was repeated five times under the same conditions
 The results were as follows:
 1 The order of screw tightening affected stress distribution The distribution was unequal and asymmetrical to the implants
 2 Staged tightening of the screws decreased the sum of all strains
 3 Tightening torque does not affect stress distribution
 4 Misfit of the abutment/superstructure joint increased the sum of all strains
 5 Strain induced by tightening of the second or third implant was greater than that by tightening the first one

Journal of Japanese Society of Oral Implantology

日本口腔インプラント学会誌


インパルス衝撃応答と骨髄圧によるオッセオインテグレーションの評価

インパルス衝撃応答と骨髄圧によるオッセオインテグレーションの評価

Purpose: The purpose of the present study was to evaluate the difference for stress transfer between titanium (Ti) and hydroxyapatite (HA) implants by measuring bone marrow pressure using a catheter pressure transducer, and then to clarify the relationship between the histological and biomechanical properties.
Methods: Ti and HA implants were inserted in the tibiae of rabbits. About 10 weeks following implantation, a hole, 1mm in diameter, was drilled in the bone distal to the implant, and a fine catheter pressure transducer was placed in the bone marrow through a tube. After the abutment was connected to the implant, the top of the abutment was vertically tapped with an impulse hammer, and the acceleration signal from the hammer, and the pressure signal from the catheter pressure transducer, were examined. In addition, histological examination was performed on each implant.
Results: Maximum bone marrow pressure (BMP) with Ti and HA was 117.4±54.8mmHg and 90.3±30.6mmHg, respectively. A significant difference was observed (p<0.05). Moreover, variation of the BMP with Ti was significantly larger than that with HA (p<0.05). A negative correlation coefficient between the time of contact recorded in the impulse and BMP was found with Ti. As to histological examination of the bone structure around several implants, no significant difference was found between Ti and HA implants.
Conclusion: The results show that the stress transfer is different between Ti and HA implants, using dynamics of bone marrow pressure. Little relation was found between biomechanical properties and histological views. The present study suggests that the evaluation of osseointegration requires consideration of biomechanical properties.

The Journal of the Japan Prosthodontic Society


Immediate implant-supported oral rehabilitation using a photocurable plastic skull model and laser welding: A technical Note of Screw Retained type: Part 1

This article describes a new procedure for immediate implant-supported oral rehabilitation using a photocurable resin skull model and a laser-welding apparatus. Preoperatively, the framework was fabricated on a photocurable resin skull model produced from a CT scan and individually designed guide template. The implants were immediately placed using the guide template; laser welding connected the components of framework. Despite the custom-made prosthesis, the total treatment from implant placement to superstructure placement can be completed within only 1 day. This procedure for immediate implant-supported oral rehabilitation using a photocurable resin skull model and a laser-welding apparatus may be useful for any implant system and patient.


The Present Condition and Problemes about Dentistry Related Assessment Itemes in The Materials of The Committee for Certification of Need for Longterm Care

介護認定審査にかかる統計資料にみる歯科関連調査項目の現状と課題

介護認定審査会における要介護認定では, 訪問調査員による認定調査表の「基本調査」と「特記事項」, かかりつけ医による「主治医意見書」を参考に, 要介護度が判定される．
しかし, 基本調査と特記事項の全85項目中, 歯科関連調査項目は, 「嚥下」, 「食事摂取」と「口腔清潔」のわずか3項目に過ぎず, また主治医意見書においても, 「歯科」受診の有無, 「嚥下性肺炎」の発生の可能性, 「訪問歯科診療」や「訪問歯科衛生指導」の必要性の有無, 「嚥下」や「摂食」についての介護サービス上の留意事項などに限られている．
そこで, 介護認定審査にかかる統計資料 (507件, 平均年齢80.4±7.5歳) について歯科関連項目の調査状況を検討し, 以下のような結論を得た．
1. 基本調査について: 要介護高齢者のおおよそ40%強は, 嚥下, 食事摂取, 口腔清潔において日常生活上何らかの介助を必要としていた．
2. 特記事項について: 口腔清潔に何らかの問題があった事例に対する特記事項の記載率は, 40%弱と嚥下や食事摂取 (70∼80%) に対してよりも低かった．
3. 主治医意見書について: 訪問歯科診療や訪問歯科衛生指導に対する必要性の認識は極めて低く, 嚥下性肺炎や摂食・嚥下障害の可能性に対して歯科系介護サービスの必要性を認めた主治医はわずか3∼5%に過ぎなかった．
このような認定調査表や主治医意見書における歯科関連項目の調査, 記載状況を改善するには, 訪問調査員や医療関係者に対する歯科的知識の啓蒙や広報活動, 口腔アセスメント表の提案や特記事項の記載方法の指導など多方面にわたる努力が必要とされよう．


Influence of thermal cycling in water on flexural strength of laboratory-processed composite resin

Recently a new generation of laboratory-processed composite resins containing submicron glass fillers was introduced, with claims of high strength. The purpose of this study was to evaluate the effect of thermal cycling in water on the flexural strength and hardness of several laboratory composite systems. The flexural strength of the new laboratory processed composite resins (Artglass [AG], Targis [TR] and Estenia [ES]) was significantly higher than that of conventional resins (Dentacolor [DC] and Cesead II [CS]). Thermocycling caused a reduction of the flexural strength but not a reduction of the hardness for most of materials tested. It was concluded that thermocycling affected the properties of the laboratory-processed hybrid type composite resin, ES, AG and TR. However, the changes of these properties were smaller than those of microfine type composite resin DC. Thus, ES, AG and TR may maintain better properties during service compared with DC.


A Study on the Contributing Factors that make Denture Usage Difficult for the Dependent Elderly

要介護高齢者の義歯使用を困難にする要因に関する研究

It is well known that whether the dependent elderly can use dentures or not depends on the degree of both their physical and mental capacities. However, we have observed several cases where two eldely persons having with similar levels of activities of daily living (ADL), a similar degree of independence in daily living, and a similar degree of dementia, differed significantly in their ability to use dentures properly.
From these cases, it can be hypothesized that the ability of the dependent elderly to use dentures properly depends not only on their actual oral condition and ADL, but also on various events in their lives such as the number of their admissions to the hospital since they started wearing dentures. In other words, the cumulative effect of various major life events influences the usage of dentures by the elderly.
Therefore, we conducted a survey designed to investigate the contributing factors that divide those elderly who wear dentures properly from those who do not .
The study participants were the edentulous individuals (71 in total; 16 males, 55 females. Average age: 85.0±5.9 years) who are residents in a geriatric hospital or in a facility of the health care servicesfor the elderly in Tokushima prefecture .
A survey was conducted on the above participants regarding their use of complete dentures, their ADL, their degree of independence for daily living, their degree of dementia, etc.
The results can be summarized as follows:
1 . The frequency of complete denture usage declined as the participant's levels of ADL, independence and dementia worsened, but this decline did not have any relationship to the times of theiradmissions to the hospital/facility or the numbers of members in their family.
2. It was suggested that, among the elderly who have a dementia and mild to low levels of ADL, their ability to wear/remove dentures and to clean the dentures by themselves relates significantly to the frequency of their denture usage .

要介護高齢者が義歯を使用できるか否かは, 身体的能力や精神的能力などによって影響されることが知られている．
しかし, 同等のADL, 日常生活の自立度や痴呆度でありながらも一方の高齢者では義歯が使用できるが, 他方の高齢者では義歯が使用できないといった事例を多々経験する．
要介護高齢者が義歯を使用できるか否かは, 単に現在の口腔内状態, ADLや痴呆度などに依存するだけでなく, 義歯を使用しなければならなくなって以来の入院歴や家族歴を始めとする人生における各種事象の影響が累積して形成された一種の生活習慣とも考えられる．
そこで, この義歯使用者と不使用者とを分ける要因を明らかにするために, 徳島県下の介護保険施設に入院・入所している上下無歯顎者 (男性16人, 女性55人, 合計71人, 平均年齢85.0±5.9歳) を対象に, 全部床義歯の使用・不使用, ADL, 口腔に関連するADL, 日常生活の自立度, 痴呆度などについて調査を行った．その結果, 以下のような結論を得た．
1.全部床義歯の使用率は, ADL, 口腔に関連するADL, 日常生活自立度, 痴呆度の悪化とともに低下したが, 入院・入所回数や同居家族数とは関連性がなかった．
2.痴呆がありADLが中等度あるいは低度の被験者群では, 義歯の着脱や口腔清掃が自分自身で可能か否かが義歯の使用率に大きく影響する可能性が示唆された．


Identification of Helicobacter Pylori in Denture Plaque of Hospitalized Aged Patients


Statistical Observation of Anterior Artificial Teeth Selected for Complete Denture

全部床義歯に用いられた前歯人工歯の統計的観察


Bone changes around hydroxyapatite and titanium implants after abutment placement in rabbits --- observations using histological and three-dimensional examinations

We have previously developed a computer-aided system for examination of the three-dimensional bone structure around implants and observed the bone changes in the healing period after implant placement. This paper describes the bone changes around hydroxyapatite (HA) and titanium (Ti) implants after abutment placement using histological and three-dimensional examinations. Twenty-four HA and Ti implants were embedded in the tibias of adult male New Zealand white rabbits. After 8 weeks, the abutment had passed through periosteum and was placed under the skin. Rabbits were sacrificed 4 and 8 weeks following abutment placement. In conclusion, histological examination showed that, at 4 weeks after abutment placement, bone resorption around the implant neck was seen in both HA and Ti implants, and at 8 weeks, excessive bone formation was seen around the implant neck. Three-dimensional bone examination showed that abutment placement may affect bone formation and cause additional bone hypertrophy in the bone marrow area.


Shock Absorbability of High-Abrasion-Resistance-Posterior Resin Teeth

硬質レジン人工臼歯の衝撃緩衝能に関する研究


インプラント上部構造のPassive fit適合試験法の検討

インプラント上部構造のPassive fit適合試験法の検討

日本口腔インプラント学会誌


Addition of the Photo-cured Composite Resin for Crown to Abrasion-resistant Plastic Posterior Denture Teeth --- Effect of Surface Treatment on Bond Strength

硬質レジン歯への光重合型硬質レジンの添加について --- 表面処理が接合強さに及ぼす影響


Flexural strength of rebased denture polymers

The properties of denture base and reline resins may be affected by daily changes between room temperature and mouth temperature. The purpose of the study was to evaluate the effect of thermocycling on the flexural strength of the relined denture base polymer with reline resin. Three denture base resins, three hard reline resins and their combinations were tested. Fourteen specimens, 65x10x2.5 mm, were fabricated for each material. Polymer combination specimens were made using 1.5 mm hard reline resin on 1.0 mm cured denture base resins. Half of the specimens were stored for 50+/-2 h in distilled water at 37 degrees C, while the other half were thermocycled for 20 000 cycles between 4 and 60 degrees C. Three point bending tests were conducted on a universal testing machine at a cross-head speed of 0.5 cm/s. The flexural strengths were measured and a statistical analysis was performed on the data using three-way ANOVA (P<0.05). The results showed that the flexural strength of relined denture base polymer was significantly higher than that of hard reline polymer. Thermocycling did not affect the flexural strength of the relined denture base polymers, whereas the denture base polymer and reline polymer alone showed a decrease in strength after thermocycling.


Observation of Tongue Pressure to Palate at Swallowing --- Comparison between Young Dentitions and Elderly Complete Denture Wearers

嚥下時の口蓋に対する舌接触圧の観察 --- 若年有歯顎者と高齢総義歯装着者の比較

The Journal of the Japan Prosthodontic Society


Influence of Buccal Interocclusal Distance on the Pressure Distribution --- In Vitro Study

頬側咬頭間隙量が負担圧分布に及ぼす影響 --- シミュレーターによる検討


Three-dimensional bone response to commercially pure titanium, hydroxyapatite, and calcium-ion-mixing titanium in rabbits

International Journal of Oral & Maxillofacial Implants


Bond Strength of Silicone Rubber Impression Materials to Self-curing Resin

シリコーンラバー印象材と常温重合レジンとの接着強さについて


Study on oral health care and general health of elderly (in Japanese)

高齢者における口腔ケアと健康に関する基礎的研究


Influence of lining design of three processed soft denture liners on cushioning effect


Influence of Anterior Palatal Form on Speech --- Part 2 Relationship to Tongue and Mandibular Movements

前方部口蓋形態が発音運動に及ぼす影響について --- 第2報 舌運動，下顎運動との関連


高周波電気メスがインプラント周囲骨組織に及ぼす影響について

高周波電気メスがインプラント周囲骨組織に及ぼす影響について

Journal of Japanese Society of Oral Implantology

日本口腔インプラント学会誌


Influence of occlusal scheme on pressure distribution under complete denture

The International Journal of Prosthodontics


Efficacy of Electrolyzed Water as Denture Cleanser --- Influence on in vitro Biofilm of Candida albicans

義歯洗浄剤としての電解水の効果 --- in vitroのCandida albicansバイオフィルムへの影響


Three-dimensional bone structure around hydroxyapatite and titanium implants in rabbits

Long-term support of dental implants requires adequate bone thickness in the area surrounding the implant. A three-dimensional examination, including calculations of percent bone-implant contact and percent bone volume, was conducted to clarify the bone structure around pure titanium (Ti) and dense hydroxyapatite (HA) implants. The implants were installed in the tibiae of rabbits, and the bone structure was examined after 2, 4, 6 and 8 weeks. The bone formation following implantation differed in the cortical bone and cancellous bone areas. In the cortical bone area, the percent bone-implant contact and percent bone volume were comparatively consistent for both Ti and HA implants during the observation period. In the cancellous bone area, both findings were influenced by the implantation period, and the chronological bone structure in the cancellous bone area also differed between Ti and HA implants. The percent bone-implant contact and percent bone volume in the Ti implant increased over 8 weeks, whereas the dense HA implant increased for the first 4 weeks and then decreased. The implant materials, Ti and HA, affected the bone remodeling in the cancellous bone area.


Denture Plaque Control for Prevention of Systemic Infection: Part 1. Identification of Helicobacter pylori in Denture Plaque. --- 第1報 デンチャープラーク中の胃潰瘍原因菌Helicobacter pyloriの検出

感染症予防のためのデンチャープラークコントロール --- 第1報 デンチャープラーク中の胃潰瘍原因菌Helicobacter pyloriの検出


パノラマX線画像の視覚評価に関する基礎的検討

パノラマX線画像の視覚評価に関する基礎的検討


部分床義歯症例の統計的観察 --- -卒前臨床実習症例について-

部分床義歯症例の統計的観察 --- -卒前臨床実習症例について-


Viscoelastic Properties of Silicone Elastomer for Maxillofacial Prosthesis

顎顔面補綴用シリコーン·エラストーマの動的粘弾性特性

Journal of the Japanese Academy of Maxillofacial Prosthetics


Influence of Implant Connection on Mandibular Flexure in Jaw Movement --- Three-dimensional Finite Element Analysis

下顎運動時の下顎骨の変形に対するインプラント連結の影響 --- 三次元有限要素法による解析

The Journal of the Japan Prosthodontic Society


Estimation of residual stress in dental porcelain by Laser-Raman spectroscopy


In vitro adherence of Streptococcus constellatus to dense hydroxyapatite and titanium

Bacterial adherence to dense hydroxyapatite (HA) and titanium (Ti) rods was examined in vitro using Streptococcus constellatus ATCC27832. Streptoccus constellatus is associated with dental abscess and was isolated from the peri-implantitis. The dense HA was etched with 5% hydrofluoric acid for 0, 10, 20, 30, 40, and 50 s Adherence to the untreated dense HA was twice as high as the adherence to the Ti. The adherence to saliva-treated Ti was 13% higher than that to untreated Ti. The adherence was increased by acid-treatment of the dense HA, following a sigmoid curve from 20 to 50 s of treatment time. The dense HA has the capacity to receive more bacterial adherence than Ti and furthermore, the etched dense HA becomes more adherent.


前方部口蓋形態が発音運動に及ぼす影響について --- 第1報 上顎中切歯部呼気圧との関連


Three-dimensional examination of bone structure around hydroxyapatite implant using digital image processing

Journal of Biomedical Materials Research


Rapid bone resorption adjacent to hydroxyapatite-coated implants

This paper describes rapid bone resorption in the peri-implantitis of HA implants based on both our clinical observations of and histological research on extracted dense hydroxyapatite (HA) implants. The surfaces of extracted HA implants were rough, although they were smooth at fixture placement. Plaque formed on the necks of the implants, whereas little plaque was seen on the bottoms. The plaque consisted of cocci and rods, including filamentous bacteria. Few spirochetes were observed. Although surrounding bone was formed rapidly around the HA implant, bone thickness gradually decreased compared with the titanium implant. These facts suggest that the rigid biointegration of HA with the thin surrounding bone--that is, the overstressing of the bone--causes rapid bone resorption rather than plaque accumulation on HA.


Influence of bone quality in the stress distribution --- An in vitro experiment

Adequate bone quality and stress distribution to the bone are of decisive importance for implant success. The purpose of this in vitro study was to investigate the influence of bone quality on the stress distribution using 2 implant-bone mimicking models, simulating compact and cancellous bone quality. The resin model was made of an acrylic resin only simulating compact bone quality. The hybrid model was made of 2 kinds of materials, acrylic resin covered with a 1-mm layer of urethane to simulate cancellous bone quality. An implant was embedded in each model, and the abutment and suprastructures were connected to the implant. A strain gauge was placed perpendicular to the implant on the surface of the model and a small accelerometer was attached to the abutment. When an impact load was applied to the suprastructure, both strain and acceleration were measured. Both abutment acceleration and surface strain in the hybrid model decreased rapidly as time progressed when compared to the resin model. Abutment accelerations in the resin model were significantly lower than those in the hybrid model. In the hybrid model, the strain increased as the loading site was moved closer to the strain gauge. The influence of loading sites on strain in the resin model was greater than in the hybrid model. Therefore, the occlusal stress was distributed more widely in the hybrid model than in the resin model. This may indicate that occlusal stress in compact bone may have a tendency to concentrate in particular regions.


Use of inter-implant displacement to measure mandibular distortion during jaw movements in human subjects


超音波計測法を用いた舌形状の動的計測 --- -咬合挙上が舌形状に及ぼす影響について-


In vitro study of mandibular implant-retained overdentures. The influence of stud attachment on load transfer to implant and soft tissue

The International Journal of Prosthodontics


老人病院入院患者の口腔状態とデンチャープラークの細菌構成について --- 第1報 予備調査結果


電解水の義歯洗浄効果 --- -細菌学的検討-

電解水の義歯洗浄効果 --- -細菌学的検討-


アパタイトインプラントの細菌付着に関する研究 --- -摘出インプラントの観察と細菌付着試験-

The Journal of the Japan Prosthodontic Society


口蓋形態の分類と音声の音響学的特徴との関連

口蓋形態の分類と音声の音響学的特徴との関連


骨粗鬆症がインプラント周囲の骨組織に及ぼす影響について

骨粗鬆症がインプラント周囲の骨組織に及ぼす影響について

Journal of Japanese Society of Oral Implantology

日本口腔インプラント学会誌


インプラントを支台としたオーバーデンチャーに関する基礎的研究 --- 第1報 スタンドアタッチメントの構造が咬合圧伝達に及ぼす影響

日本口腔インプラント学会誌


GTR法を用いたApatite 2-Piece Implant 周囲骨組織の経時変化

日本口腔インプラント学会雑誌

日本口腔インプラント学会雑誌


Influence of alteration in the oral environment on speech production


骨結合型インプラントを利用した下顎運動時の下顎骨体の歪測定

骨結合型インプラントを利用した下顎運動時の下顎骨体の歪測定


骨質がアパタイトインプラントの術後経過に及ぼす影響 --- -臨床治験結果と模型実験からの検討-

日本口腔インプラント学会誌


Pilot-hole preparation for proper implant positioning and the enhancement of bone formation

We have demonstrated a new insertion technique, "pilot-hole preparation", for proper implant positioning. The purpose of this study was to investigate the histological and biomechanical efficacies of the technique. We analyzed the influence of implant position on the stress distribution to the bone by the two-dimensional finite element method (FEM). In addition, we studied the influence of the pre-operative pilot-hole preparation on the bone tissue in vivo using histological examination.


Studies on the Mobility of Complete dentures --- Part 1. Investigation of a Method of Measurement and Analysis using MKG

全部床義歯の動揺について --- 第1報 MKGを用いた測定分析方法の検討


Studies on Reproduction of Condylar Path by means of Articulators --- Part 1. Semi-Adiustable Articulators

咬合器の顆路再現性に関する研究 --- 第1報 半調節性咬合器


Studies on Mechanism of Speech --- Part1. Normal Subjects

発音のメカニズムに関する研究 --- 第1報 正常有歯顎者


Problems on the Time character of the Mandibular Kinesiograph

MKGを用いた下顎運動の計時的測定に際して注意すべき2，3の問題点について


The cyanine dye triS-C4(5) as a cationic uncoupler of oxidative phosphorylation: Interaction with mitochondria detected by derivative spectrophotometry

微分吸収スペクトル法を用いてtri-S-C4(5)のミトコンドリアへの結合と，脱共役作用及びミトコンドリア体積膨潤作用を経時的に比較した．その結果，無機リン酸イオン存在下で脱共役状態のミトコンドリアに対してよりも，無機リン酸イオン非存在下で共役状態のミトコンドリアへの結合量が大幅に多く，しかもその際にミトコンドリアは収縮しており，tri-S-C4(5)がミトコンドリア内に蓄積する事が脱共役作用の原因では無いことを分光学的に示した．


Robotics in Dentistry: A Narrative Review

Robotics is progressing rapidly. The aim of this study was to provide a comprehensive overview of the basic and applied research status of robotics in dentistry and discusses its development and application prospects in several major professional fields of dentistry. A literature search was conducted on databases: MEDLINE, IEEE and Cochrane Library, using MeSH terms: ["robotics" and "dentistry"]. Forty-nine articles were eventually selected according to certain inclusion criteria. There were 12 studies on prosthodontics, reaching 24%; 11 studies were on dental implantology, accounting for 23%. Scholars from China published the most articles, followed by Japan and the United States. The number of articles published between 2011 and 2015 was the largest. With the advancement of science and technology, the applications of robots in dental medicine has promoted the development of intelligent, precise, and minimally invasive dental treatments. Currently, robots are used in basic and applied research in various specialized fields of dentistry. Automatic tooth-crown-preparation robots, tooth-arrangement robots, drilling robots, and orthodontic archwire-bending robots that meet clinical requirements have been developed. We believe that in the near future, robots will change the existing dental treatment model and guide new directions for further development.


一般照明および植物育成照明に応用できる新しいLED照明方法の開発

一般照明および植物育成照明に応用できる新しいLED照明方法の開発

LED総合フォーラム2018 in 徳島 論文集

LED総合フォーラム2018 in 徳島 論文集


social supoort for persons with cognitive dysfunction

高次脳機能障害者を支える法制度(社会的支援)

The Japanese Journal of Rehabilitation Medicine


歯科用金属による金属アレルギーの臨床病態と補綴学的対応に関する多施設調査

歯科用金属による金属アレルギーの臨床病態と補綴学的対応に関する多施設調査

Journal of the Japanese Association for Dental Science


キャリア形成支援教育プログラムの開発と教育効果の評価-「チーム医療体験学習」の実践的研究を通して-

We prepared career advancement program "Experience learning in medical team treatment" towards the second，third and fouth year students of dental school. This program consits of prior learningconcerned with 'Team treatment and Dental profession' and experience learning in medical team treatment at Tokushima University Hospital.The purpose of this program was to rouse career conciousness as a dentalprofession. This program provided students with career image which they want to be in the future. Besides，they were motivated to study more widely to approach their own image. In this paper，we evaluated theeffects of the program"The experience learning in medical team treatment" on career advancement ofdental school students. As a result，it is suggested that this program might be fruitful as career advancement on dental students.我々は歯学部学生のキャリア形成支援のための教育プログラム「チーム医療体験学習」を開発し，歯学部の2，3，4年次の学生を対象として実施した．本プログラムは，グループワークによる事前学習とチーム医療の現場体験を2つの柱とし，学生の歯科医療職としてのキャリア意識を強化することを目的とした．プログラム終了時のアンケートから，学生には歯科専門職としての将来の姿勢や目指す方向性が具体化すると同時に幅広い知識を身につけたいといった学習に対する動機付が強化されるなど明らかな教育成果が認められた．プログラム実施前後のアンケートの分析結果から， 「チーム医療体験学習」が歯学部学生のキャリア形成支援教育の手法として有効なプログラムである可能性が示唆された．

Journal of University Education Research


デンタルデバイス感染症 --- デンチャープラークから高齢者の健康を考える

デンタルデバイス感染症 --- デンチャープラークから高齢者の健康を考える


デンチャープラークの最前線

デンチャープラークの最前線


要介護高齢者における咽頭微生物叢について --- 特に義歯装着の有無による影響

要介護高齢者における咽頭微生物叢について --- 特に義歯装着の有無による影響


電解水を利用した義歯洗浄機 イオデント

電解水を利用した義歯洗浄機 イオデント


含嗽の咽頭ぬぐい液細菌数に対する影響

含嗽の咽頭ぬぐい液細菌数に対する影響

Bulletin of School of Medical Sciences, the University of Tokushima

徳島大学医療技術短期大学部紀要


Effect of barium in porcelain on bonding strength of titanium-porcelain system.

The bonding strength to titanium, thermal expansion, and bending strength of glassy porcelain containing barium of 5, 10, and 15 mass% were estimated and compared with those of barium-free porcelain, to estimate the effect of barium content on bonding strength to titanium. The three different glassy porcelains containing barium were made by melting at 950 degrees C. The bonding strength of a commercial porcelain to titanium increased with the addition of barium. Bending strength and thermal expansion were not affected by the barium content. Therefore, the addition of barium to porcelain is effective for strengthening the bonding of porcelain to titanium.