=== Generating (published_papers) ===
=== Generating (research_interests) ===
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=== Generating (research_experience) ===
=== Generating (misc) ===
=== Generating (research_projects) ===
=== Generating (books_etc) ===
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=== Generating (presentations) ===
==== begin registerFile(/WWW/pub2/data/ERD/person/60338/researchmap/published_papers.jsonl) ====
line:1, {"insert":{"user_id":"1000242796","type":"published_papers","id":"42931267"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/36288959","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85166383313&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=398994","label":"url"}],"paper_title":{"en":"2-methacryloyloxyethyl phosphorylcholine polymer treatment prevents Candida albicans biofilm formation on acrylic resin","ja":"2-methacryloyloxyethyl phosphorylcholine polymer treatment prevents Candida albicans biofilm formation on acrylic resin"},"authors":{"en":[{"name":"Wigianto Putra Yoshi Adityakrisna"},{"name":"Ishida Yuichi"},{"name":"Iwawaki Yuki"},{"name":"Goto Takaharu"},{"name":"Watanabe Megumi"},{"name":"Sekine Kazumitsu"},{"name":"Hamada Kenichi"},{"name":"Murakami Keiji"},{"name":"Fujii Hideki"},{"name":"Ichikawa Tetsuo"}],"ja":[{"name":"Wigianto Putra Yoshi Adityakrisna"},{"name":"石田 雄一"},{"name":"岩脇 有軌"},{"name":"後藤 崇晴"},{"name":"渡邉 恵"},{"name":"関根 一光"},{"name":"浜田 賢一"},{"name":"村上 圭史"},{"name":"藤猪 英樹"},{"name":"市川 哲雄"}]},"description":{"en":"We aimed to evaluate the effectiveness of photoreactive 2-methacryloyloxyethyl phosphorylcholine (MPC) in inhibiting Candida albicans biofilm formation on polymethyl methacrylate (PMMA) and assess its mechanism and need for re-application by evaluating its interaction with salivary mucin and durability during temperature changes. PMMA discs were used as specimens. The MPC coating was applied using the spray and cure technique for the treatment groups, whereas no coating was applied to the control. The MPC treatment (MT) groups were further differentiated based on the number of thermal cycles involved (0, 1000, 2500, and 5000). The optical density was measured to assess mucin adsorption (MA). Contact angle (CA) was calculated to evaluate surface hydrophilicity. The presence of MPC components on the PMMA surface was assessed using X-ray photoelectron spectroscopy (XPS). C. albicans biofilms were evaluated qualitatively (scanning electron microscope images) and quantitatively (colony-forming units (CFUs)). Statistical analysis was conducted using two-way analysis of variance and Tukey's multiple comparison test. MA rate and CA increased significantly in the MT groups, which exhibited significantly fewer CFUs and thinner biofilms than those of the control group. Based on the XPS, MA, and CFU evaluations, the durability and efficacy of the MPC coating were considered stable up to 2500 thermal cycles. Additionally, a significant interaction was observed between mucin concentration and MPC efficacy. The photoreactive MPC coating, which was resistant to temperature changes for approximately 3 months, effectively prevented C. albicans biofilm formation by modifying surface hydrophilicity and increasing mucin adsorption.","ja":"We aimed to evaluate the effectiveness of photoreactive 2-methacryloyloxyethyl phosphorylcholine (MPC) in inhibiting Candida albicans biofilm formation on polymethyl methacrylate (PMMA) and assess its mechanism and need for re-application by evaluating its interaction with salivary mucin and durability during temperature changes. PMMA discs were used as specimens. The MPC coating was applied using the spray and cure technique for the treatment groups, whereas no coating was applied to the control. The MPC treatment (MT) groups were further differentiated based on the number of thermal cycles involved (0, 1000, 2500, and 5000). The optical density was measured to assess mucin adsorption (MA). Contact angle (CA) was calculated to evaluate surface hydrophilicity. The presence of MPC components on the PMMA surface was assessed using X-ray photoelectron spectroscopy (XPS). C. albicans biofilms were evaluated qualitatively (scanning electron microscope images) and quantitatively (colony-forming units (CFUs)). Statistical analysis was conducted using two-way analysis of variance and Tukey's multiple comparison test. MA rate and CA increased significantly in the MT groups, which exhibited significantly fewer CFUs and thinner biofilms than those of the control group. Based on the XPS, MA, and CFU evaluations, the durability and efficacy of the MPC coating were considered stable up to 2500 thermal cycles. Additionally, a significant interaction was observed between mucin concentration and MPC efficacy. The photoreactive MPC coating, which was resistant to temperature changes for approximately 3 months, effectively prevented C. albicans biofilm formation by modifying surface hydrophilicity and increasing mucin adsorption."},"publication_date":"2022-10-27","publication_name":{"en":"Journal of Prosthodontic Research","ja":"Journal of Prosthodontic Research"},"volume":"Vol.67","number":"No.3","starting_page":"384","ending_page":"391","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2186/jpr.JPR_D_22_00102"],"issn":["2212-4632"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:2, {"insert":{"user_id":"1000242796","type":"published_papers","id":"39213766"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/117038","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/35264547","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=384672","label":"url"}],"paper_title":{"en":"Effect of immersion in NaCl solution on the electrical conductivity and the reduction of the shear bond strength of resin-modifi ed glass-ionomer-cements after current application","ja":"Effect of immersion in NaCl solution on the electrical conductivity and the reduction of the shear bond strength of resin-modifi ed glass-ionomer-cements after current application"},"authors":{"en":[{"name":"Matsuki Yuta"},{"name":"Sato Hiroko"},{"name":"Kajimoto N,"},{"name":"Takegawa Emi"},{"name":"Horiuchi Shinya"},{"name":"Sekine Kazumitsu"},{"name":"Tanaka Eiji"},{"name":"Hamada Kenichi"}],"ja":[{"name":"松木 祐太"},{"name":"佐藤 博子"},{"name":"梶本 昇"},{"name":"武川 恵美"},{"name":"堀内 信也"},{"name":"関根 一光"},{"name":"田中 栄二"},{"name":"浜田 賢一"}]},"publication_date":"2022-05","publication_name":{"en":"Dental Materials Journal","ja":"Dental Materials Journal"},"volume":"Vol.41","number":"No.3","starting_page":"487","ending_page":"494","languages":["eng"],"referee":true,"identifiers":{"doi":["10.4012/dmj.2021-322"],"issn":["1881-1361"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:3, {"insert":{"user_id":"1000242796","type":"published_papers","id":"36463232"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116783","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=384482","label":"url"}],"paper_title":{"en":"Volume Magnetic Susceptibility Estimation of α- and β-Phases in Titanium Alloys for Biomedical Applications.","ja":"Volume Magnetic Susceptibility Estimation of α- and β-Phases in Titanium Alloys for Biomedical Applications."},"authors":{"en":[{"name":"Yoshimura Muneyuki"},{"name":"Takegawa Emi"},{"name":"Sekine Kazumitsu"},{"name":"Horiuchi Shinya"},{"name":"Tanaka Eiji"},{"name":"Hamada Kenichi"}],"ja":[{"name":"吉村 宗之"},{"name":"武川 恵美"},{"name":"関根 一光"},{"name":"堀内 信也"},{"name":"田中 栄二"},{"name":"浜田 賢一"}]},"description":{"en":"Metallic medical devices in the human body cause serious artifacts in magnetic resonance imaging owing to the volume magnetic susceptibility (χν) mismatch between the device and tissue around the device. To reduce artifacts, medical devices produced from alloys with χν values of approximately -9 × 10-6 are required. Controlling the phase constitution is a basic technique used to control the χν value of an alloy, and the χν value of each phase is a fundamental property. In this study, an α+β-type Ti alloy and two β-type Ti alloys were investigated. The estimated χν values of the α-phase of the alloys were similar to or smaller than that of pure Ti. In contrast, the estimated χν values of the β-phase of the alloys were larger than that of pure Ti. Since the χν value of pure Ti is much larger than -9 × 10-6, the χν values of the β-phases suggested that increasing the volume fraction of the β-phase was not appropriate for producing a Ti alloy with a lower χν value.","ja":"Metallic medical devices in the human body cause serious artifacts in magnetic resonance imaging owing to the volume magnetic susceptibility (χν) mismatch between the device and tissue around the device. To reduce artifacts, medical devices produced from alloys with χν values of approximately -9 × 10-6 are required. Controlling the phase constitution is a basic technique used to control the χν value of an alloy, and the χν value of each phase is a fundamental property. In this study, an α+β-type Ti alloy and two β-type Ti alloys were investigated. The estimated χν values of the α-phase of the alloys were similar to or smaller than that of pure Ti. In contrast, the estimated χν values of the β-phase of the alloys were larger than that of pure Ti. Since the χν value of pure Ti is much larger than -9 × 10-6, the χν values of the β-phases suggested that increasing the volume fraction of the β-phase was not appropriate for producing a Ti alloy with a lower χν value."},"publication_date":"2022-03-06","publication_name":{"en":"Journal of Oral Health and Biosciences","ja":"Journal of Oral Health and Biosciences"},"volume":"Vol.34","number":"No.2","starting_page":"34","ending_page":"39","languages":["eng"],"referee":true,"identifiers":{"doi":["10.20738/johb.34.2_34"],"issn":["2189-6682"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:4, {"insert":{"user_id":"1000242796","type":"published_papers","id":"39213768"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116714","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/34193725","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=376730","label":"url"}],"paper_title":{"en":"Influence of insertion depth on stress distribution in orthodontic miniscrew and the surrounding bone by finite element analysis.","ja":"Influence of insertion depth on stress distribution in orthodontic miniscrew and the surrounding bone by finite element analysis."},"authors":{"en":[{"name":"Hirai Yuzo"},{"name":"Watanabe Keiichiro"},{"name":"Deguchi Toru"},{"name":"Ueda Kanji"},{"name":"Hamada Kenichi"},{"name":"Tanaka Eiji"}],"ja":[{"name":"平井 雄三"},{"name":"渡邉 佳一郎"},{"name":"Deguchi Toru"},{"name":"Ueda Kanji"},{"name":"浜田 賢一"},{"name":"田中 栄二"}]},"description":{"en":"We aimed to elucidate stress distribution in miniscrews and the surrounding bone when miniscrews inserted at different depths were implanted vertically or obliquely. The distributions of the equivalent stress on the screw surface and the minimum principal stress in the surrounding bone were calculated using finite element models. When the miniscrews were inserted vertically and obliquely, screw head displacement, greatest equivalent stress on the miniscrew surface, and absolute value of minimum principal stresses in the surrounding bone decreased with increasing insertion depth. Stresses in the obliquely inserted miniscrew with upward traction were smaller than in other insertion conditions, irrespective of insertion depth. With the application of orthodontic force, stress distribution around the miniscrew and surrounding bone is closely related to the insertion depth and insertion angle, which mutually affect each other. In particular, the obliquely inserted miniscrew with upward traction might be the most secure against screw failure and fracture.","ja":"We aimed to elucidate stress distribution in miniscrews and the surrounding bone when miniscrews inserted at different depths were implanted vertically or obliquely. The distributions of the equivalent stress on the screw surface and the minimum principal stress in the surrounding bone were calculated using finite element models. When the miniscrews were inserted vertically and obliquely, screw head displacement, greatest equivalent stress on the miniscrew surface, and absolute value of minimum principal stresses in the surrounding bone decreased with increasing insertion depth. Stresses in the obliquely inserted miniscrew with upward traction were smaller than in other insertion conditions, irrespective of insertion depth. With the application of orthodontic force, stress distribution around the miniscrew and surrounding bone is closely related to the insertion depth and insertion angle, which mutually affect each other. In particular, the obliquely inserted miniscrew with upward traction might be the most secure against screw failure and fracture."},"publication_date":"2021-09-30","publication_name":{"en":"Dental Materials Journal","ja":"Dental Materials Journal"},"volume":"Vol.40","number":"No.5","starting_page":"1270","ending_page":"1276","languages":["eng"],"referee":true,"identifiers":{"doi":["10.4012/dmj.2020-400"],"issn":["1881-1361"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:5, {"insert":{"user_id":"1000242796","type":"published_papers","id":"30550703"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/114725","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/32779608","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=363572","label":"url"}],"paper_title":{"en":"Effects of water immersion on shear bond strength reduction after current application of resin-modified glass-ionomer-cements containing and not containing an ionic liquid.","ja":"Effects of water immersion on shear bond strength reduction after current application of resin-modified glass-ionomer-cements containing and not containing an ionic liquid."},"authors":{"en":[{"name":"Sato Hiroko"},{"name":"Matsuki Yuta"},{"name":"Kajimoto N,"},{"name":"Takegawa Emi"},{"name":"Horiuchi Shinya"},{"name":"Sekine Kazumitsu"},{"name":"Tanaka Eiji"},{"name":"Hamada Kenichi"}],"ja":[{"name":"佐藤 博子"},{"name":"松木 祐太"},{"name":"梶本 昇"},{"name":"武川 恵美"},{"name":"堀内 信也"},{"name":"関根 一光"},{"name":"田中 栄二"},{"name":"浜田 賢一"}]},"description":{"en":"The enhancement in the bonding strength of advanced dental cements has enabled long-lasting dental restorations. However, the high bonding strength can cause difficulty in removing these restorations. Therefore, \"smart\" dental cements with simultaneous strong bonding and easy on-demand debonding ability are required. A resin-modified glass-ionomer-cement (RMGIC) with an ionic liquid (IL) has demonstrated significant reduction in the bonding strength with current application (CA). This research investigates the effect of immersion in distilled water on the electric conductivity and bonding strength of RMGIC with and without an IL and CA. The RMGIC without the IL exhibited significant electric conductivity after immersion, and a significant decrease in bonding strength with CA. In comparison, the electric conductivity after immersion and the decrease in bonding strength with CA were greater for RMGIC with the IL. Thus, the feasibility of smart dental cements capable of electrically debonding-on-demand is indicated.","ja":"The enhancement in the bonding strength of advanced dental cements has enabled long-lasting dental restorations. However, the high bonding strength can cause difficulty in removing these restorations. Therefore, \"smart\" dental cements with simultaneous strong bonding and easy on-demand debonding ability are required. A resin-modified glass-ionomer-cement (RMGIC) with an ionic liquid (IL) has demonstrated significant reduction in the bonding strength with current application (CA). This research investigates the effect of immersion in distilled water on the electric conductivity and bonding strength of RMGIC with and without an IL and CA. The RMGIC without the IL exhibited significant electric conductivity after immersion, and a significant decrease in bonding strength with CA. In comparison, the electric conductivity after immersion and the decrease in bonding strength with CA were greater for RMGIC with the IL. Thus, the feasibility of smart dental cements capable of electrically debonding-on-demand is indicated."},"publication_date":"2021-01","publication_name":{"en":"Dental Materials Journal","ja":"Dental Materials Journal"},"volume":"Vol.40","number":"No.1","starting_page":"35","ending_page":"43","languages":["eng"],"referee":true,"identifiers":{"doi":["10.4012/dmj.2019-371"],"issn":["1881-1361"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:6, {"insert":{"user_id":"1000242796","type":"published_papers","id":"33359786"},"force":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/116056","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=395774","label":"url"}],"paper_title":{"en":"Effects of zirconia additives on β-tricalcium-phosphate cement for high strength and high injectability","ja":"Effects of zirconia additives on β-tricalcium-phosphate cement for high strength and high injectability"},"authors":{"en":[{"name":"Kim Yeeun"},{"name":"Be Jiyon"},{"name":"Takegawa Emi"},{"name":"Sekine Kazumitsu"},{"name":"Kawano Fumiaki"},{"name":"Hamada Kenichi"}],"ja":[{"name":"キム イエウン"},{"name":"裵 志英"},{"name":"武川 恵美"},{"name":"関根 一光"},{"name":"河野 文昭"},{"name":"浜田 賢一"}]},"publication_date":"2021-01-15","publication_name":{"en":"Ceramics International","ja":"Ceramics International"},"volume":"Vol.47","number":"No.2","starting_page":"1882","ending_page":"1890","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.ceramint.2020.09.017"],"issn":["0272-8842"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:7, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111728","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/29848856","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85056973389&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=337897","label":"url"}],"paper_title":{"en":"Electrical shear bonding strength reduction of resin-modified glass-ionomer-cement containing ionic-liquid concept and validation of a smart dental cement debonding-on-demand","ja":"Electrical shear bonding strength reduction of resin-modified glass-ionomer-cement containing ionic-liquid concept and validation of a smart dental cement debonding-on-demand"},"authors":{"en":[{"name":"Kajimoto Noboru"},{"name":"Takegawa Emi"},{"name":"Sekine Kazumitsu"},{"name":"Hamada Kenichi"}],"ja":[{"name":"Kajimoto Noboru"},{"name":"武川 恵美"},{"name":"関根 一光"},{"name":"浜田 賢一"}]},"description":{"en":"With improvement of bonding strength of recent dental cement, it is difficult nowadays to remove restorations without excessive force or vibration to tooth, occasionally resulting in damage of dentin, enamel, and dental root. Therefore, \"smart\" dental cement indicating strong bonding and easy debonding-on-demand simultaneously is required. In this research, resin-modified glass-ionomer-cement containing an ionic-liquid, tris(2-hydroxyethyl)methylammonium methylsulfate was produced, and the shear bonding strength before and after direct current application were evaluated. The prototype cement containing 15 to 20 mass% ionic-liquid indicated simultaneously no significant reduction of shear bonding strength from that of the original cement not containing ionic-liquid, and significant reduction of bonding strength to approximately 20% of that of the original cement after direct current application of more than 2 mmC/mm. The prototype cement in this research demonstrated that the concept of smart dental cement electrically debonding-on-demand is feasible.","ja":"With improvement of bonding strength of recent dental cement, it is difficult nowadays to remove restorations without excessive force or vibration to tooth, occasionally resulting in damage of dentin, enamel, and dental root. Therefore, \"smart\" dental cement indicating strong bonding and easy debonding-on-demand simultaneously is required. In this research, resin-modified glass-ionomer-cement containing an ionic-liquid, tris(2-hydroxyethyl)methylammonium methylsulfate was produced, and the shear bonding strength before and after direct current application were evaluated. The prototype cement containing 15 to 20 mass% ionic-liquid indicated simultaneously no significant reduction of shear bonding strength from that of the original cement not containing ionic-liquid, and significant reduction of bonding strength to approximately 20% of that of the original cement after direct current application of more than 2 mmC/mm. The prototype cement in this research demonstrated that the concept of smart dental cement electrically debonding-on-demand is feasible."},"publication_date":"2018-05","publication_name":{"en":"Dental Materials Journal","ja":"Dental Materials Journal"},"volume":"Vol.37","number":"No.5","starting_page":"768","ending_page":"774","languages":["eng"],"referee":true,"identifiers":{"doi":["10.4012/dmj.2017-361"],"issn":["1881-1361"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:8, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/111978","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/28450674","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-85030149005&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=323603","label":"url"}],"paper_title":{"en":"Effects of powder-to-liquid ratio on properties of β-tricalcium-phosphate cements modified using high-energy ball-milling","ja":"Effects of powder-to-liquid ratio on properties of β-tricalcium-phosphate cements modified using high-energy ball-milling"},"authors":{"en":[{"name":"Ida Yumika"},{"name":"Be Jiyon"},{"name":"Sekine Kazumitsu"},{"name":"Kawano Fumiaki"},{"name":"Hamada Kenichi"}],"ja":[{"name":"伊田 百美香"},{"name":"裵 志英"},{"name":"関根 一光"},{"name":"河野 文昭"},{"name":"浜田 賢一"}]},"description":{"en":"The authors have developed a β-tricalcium-phosphate (β-TCP) powder modified mechano-chemically through the application of a ball-milling process (mβ-TCP). The resulting powder can be used in a calcium-phosphate-cement (CPC). In this study, the effects of the powder-to-liquid ratio (P/L ratio) on the properties of the CPCs were investigated, and an appropriate P/L ratio that would simultaneously improve injectability and strength was clarified. The mβ-TCP cement mixed at a P/L ratio of 2.5 and set in air exhibited sufficient injectability until 20 min after mixing, and strength similar to or higher than that mixed at a P/L ratio of 2.0 and 2.78. Although the mβ-TCP cements set in vivo and in SBF were found to exhibit a lower strength than those set in air, it did have an appropriate setting time and strength for clinical applications. In conclusion, P/L ratio optimization successfully improved the strength of injectable mβ-TCP cement.","ja":"The authors have developed a β-tricalcium-phosphate (β-TCP) powder modified mechano-chemically through the application of a ball-milling process (mβ-TCP). The resulting powder can be used in a calcium-phosphate-cement (CPC). In this study, the effects of the powder-to-liquid ratio (P/L ratio) on the properties of the CPCs were investigated, and an appropriate P/L ratio that would simultaneously improve injectability and strength was clarified. The mβ-TCP cement mixed at a P/L ratio of 2.5 and set in air exhibited sufficient injectability until 20 min after mixing, and strength similar to or higher than that mixed at a P/L ratio of 2.0 and 2.78. Although the mβ-TCP cements set in vivo and in SBF were found to exhibit a lower strength than those set in air, it did have an appropriate setting time and strength for clinical applications. In conclusion, P/L ratio optimization successfully improved the strength of injectable mβ-TCP cement."},"publication_date":"2017-04-26","publication_name":{"en":"Dental Materials Journal","ja":"Dental Materials Journal"},"volume":"Vol.36","number":"No.5","starting_page":"590","ending_page":"599","languages":["eng"],"referee":true,"identifiers":{"doi":["10.4012/dmj.2016-341"],"issn":["1881-1361"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:9, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/110121","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=321865","label":"url"}],"paper_title":{"en":"Volume magnetic susceptibility design and hardness of Au Ta alloys and Au Nb alloys for MRI-compatible biomedical applications","ja":"Volume magnetic susceptibility design and hardness of Au Ta alloys and Au Nb alloys for MRI-compatible biomedical applications"},"authors":{"en":[{"name":"Inui Shihoko"},{"name":"Takegawa Emi"},{"name":"Hamada Kenichi"}],"ja":[{"name":"乾 志帆子"},{"name":"武川 恵美"},{"name":"浜田 賢一"}]},"publication_date":"2017-02-10","publication_name":{"en":"Biomedical Physics & Engineering Express","ja":"Biomedical Physics & Engineering Express"},"volume":"Vol.3","number":"No.1","starting_page":"015025","ending_page":"015025","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1088/2057-1976/aa5449"],"issn":["2057-1976"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:10, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://repo.lib.tokushima-u.ac.jp/ja/110102","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/28154746","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=322006","label":"url"}],"paper_title":{"en":"Bone Ingrowth to Ti Fibre Knit Block with High Deformability","ja":"Bone Ingrowth to Ti Fibre Knit Block with High Deformability"},"authors":{"en":[{"name":"Henmi Yoko"},{"name":"Naitou Yoshihito"},{"name":"Jimbo Ryo"},{"name":"Jinno Yohei"},{"name":"Sekine Kazumitsu"},{"name":"Hamada Kenichi"}],"ja":[{"name":"邉見 蓉子"},{"name":"内藤 禎人"},{"name":"神保 良"},{"name":"神野 洋平"},{"name":"関根 一光"},{"name":"浜田 賢一"}]},"publication_date":"2016-12-23","publication_name":{"en":"Journal of Oral & Maxillofacial Research","ja":"Journal of Oral & Maxillofacial Research"},"volume":"Vol.7","number":"No.4","starting_page":"e2","ending_page":"e2","languages":["eng"],"referee":true,"identifiers":{"doi":["10.5037/jomr.2016.7402"],"issn":["2029-283X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:11, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/25855467","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84926341883&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=291870","label":"url"}],"paper_title":{"en":"Effects of high-energy ball-milling on injectability and strength of β-tricalcium-phosphate cement","ja":"Effects of high-energy ball-milling on injectability and strength of β-tricalcium-phosphate cement"},"authors":{"en":[{"name":"Be Jiyon"},{"name":"Ida Yumika"},{"name":"Sekine Kazumitsu"},{"name":"Kawano Fumiaki"},{"name":"Hamada Kenichi"}],"ja":[{"name":"裵 志英"},{"name":"伊田 百美香"},{"name":"関根 一光"},{"name":"河野 文昭"},{"name":"浜田 賢一"}]},"description":{"en":"Calcium phosphate cement (CPC) offers many advantages as a bone-substitution material. The objective of this study is to develop a new CPC that simultaneously exhibits fine injectability, a short setting time, and high strength. β-tricalcium phosphate (β-TCP, control) powder was ball-milled for 24h to produce a new cement powder. The modified β-TCP after 24h milling (mβ-TCP-24h) exhibited excellent injectability even 1h after mixing. The mechanical properties of the set cement (compact) were evaluated using compressive strength (CS) and diametral tensile strength (DTS) testing. The CS and DTS values of the mβ-TCP-24h compacts were 8.02MPa and 2.62MPa, respectively, at 5h after mixing, and were 49.6MPa and 7.9MPa, respectively, at 2 weeks after mixing. All the CS and DTS values of the mβ-TCP-24h compacts were significantly higher than those of the control for the same duration after mixing. These results suggest that the mechano-chemically modified β-TCP powder dissolves rapidly and accelerates hydroxyapatite precipitation, which successfully shortens the cement setting time and enhances the strength. This study supports that mβ-TCP-24h is a promising candidate for use in injectable CPCs with improved strength.","ja":"Calcium phosphate cement (CPC) offers many advantages as a bone-substitution material. The objective of this study is to develop a new CPC that simultaneously exhibits fine injectability, a short setting time, and high strength. β-tricalcium phosphate (β-TCP, control) powder was ball-milled for 24h to produce a new cement powder. The modified β-TCP after 24h milling (mβ-TCP-24h) exhibited excellent injectability even 1h after mixing. The mechanical properties of the set cement (compact) were evaluated using compressive strength (CS) and diametral tensile strength (DTS) testing. The CS and DTS values of the mβ-TCP-24h compacts were 8.02MPa and 2.62MPa, respectively, at 5h after mixing, and were 49.6MPa and 7.9MPa, respectively, at 2 weeks after mixing. All the CS and DTS values of the mβ-TCP-24h compacts were significantly higher than those of the control for the same duration after mixing. These results suggest that the mechano-chemically modified β-TCP powder dissolves rapidly and accelerates hydroxyapatite precipitation, which successfully shortens the cement setting time and enhances the strength. This study supports that mβ-TCP-24h is a promising candidate for use in injectable CPCs with improved strength."},"publication_date":"2015-03-10","publication_name":{"en":"Journal of the Mechanical Behavior of Biomedical Materials","ja":"Journal of the Mechanical Behavior of Biomedical Materials"},"volume":"Vol.47","starting_page":"77","ending_page":"86","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jmbbm.2015.03.005"],"issn":["1751-6161"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:12, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=384240","label":"url"}],"paper_title":{"en":"Effects of high-energy ball-milling on injectability and strength of β-tricalcium-phosphate cement","ja":"Effects of high-energy ball-milling on injectability and strength of β-tricalcium-phosphate cement"},"authors":{"en":[{"name":"Ji-young Bae"},{"name":"Ida Yumika"},{"name":"Sekine Kazumitsu"},{"name":"Kawano Fumiaki"},{"name":"Hamada Kenichi"}],"ja":[{"name":"Ji-young Bae"},{"name":"伊田 百美香"},{"name":"関根 一光"},{"name":"河野 文昭"},{"name":"浜田 賢一"}]},"publication_date":"2015","publication_name":{"en":"Journal of the Mechanical Behavior of Biomedical Materials","ja":"Journal of the Mechanical Behavior of Biomedical Materials"},"number":"No.47","starting_page":"77","ending_page":"86","languages":["eng"],"referee":true,"identifiers":{"issn":["1751-6161"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:13, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/24787487","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=283755","label":"url"}],"paper_title":{"en":"Pim-2 kinase is an important target of treatment for tumor progression and bone loss in myeloma.","ja":"Pim-2 kinase is an important target of treatment for tumor progression and bone loss in myeloma."},"authors":{"en":[{"name":"Hiasa Masahiro"},{"name":"Teramachi Jumpei"},{"name":"Oda A"},{"name":"Amachi Ryota"},{"name":"Harada T"},{"name":"Nakamura Shingen"},{"name":"Miki Hirokazu"},{"name":"Fujii Shiroh"},{"name":"Kagawa Kumiko"},{"name":"Watanabe Keiichiro"},{"name":"Endo Itsuro"},{"name":"Kuroda Y"},{"name":"Yoneda T"},{"name":"Tsuji Daisuke"},{"name":"Nakao Michiyasu"},{"name":"Tanaka Eiji"},{"name":"Hamada Kenichi"},{"name":"Sano Shigeki"},{"name":"Itou Kouji"},{"name":"Matsumoto Toshio"},{"name":"Abe Masahiro"}],"ja":[{"name":"日浅 雅博"},{"name":"寺町 順平"},{"name":"Oda A"},{"name":"天知 良太"},{"name":"Harada T"},{"name":"中村 信元"},{"name":"三木 浩和"},{"name":"藤井 志朗"},{"name":"賀川 久美子"},{"name":"渡邉 佳一郎"},{"name":"遠藤 逸朗"},{"name":"Kuroda Y"},{"name":"Yoneda T"},{"name":"辻 大輔"},{"name":"中尾 允泰"},{"name":"田中 栄二"},{"name":"浜田 賢一"},{"name":"佐野 茂樹"},{"name":"伊藤 孝司"},{"name":"松本 俊夫"},{"name":"安倍 正博"}]},"description":{"en":"Pim-2 kinase is overexpressed in multiple myeloma (MM) cells to enhance their growth and survival, and regarded as a novel therapeutic target in MM. However, the impact of Pim-2 inhibition on bone disease in MM remains unknown. We demonstrated here that Pim-2 expression was also upregulated in bone marrow stromal cells and MC3T3-E1 preosteoblastic cells in the presence of cytokines known as the inhibitors of osteoblastogenesis in MM, including interleukin-3 (IL-3), IL-7, tumor necrosis factor-, transforming growth factor- (TGF-) and activin A, as well as MM cell conditioned media. The enforced expression of Pim-2 abrogated in vitro osteoblastogenesis by BMP-2, which suggested Pim-2 as a negative regulator for osteoblastogenesis. Treatment with Pim-2 short-interference RNA as well as the Pim inhibitor SMI-16a successfully restored osteoblastogenesis suppressed by all the above inhibitory factors and MM cells. The SMI-16a treatment potentiated BMP-2-mediated anabolic signaling while suppressing TGF- signaling. Furthermore, treatment with the newly synthesized thiazolidine-2,4-dione congener, 12a-OH, as well as its prototypic SMI-16a effectively prevented bone destruction while suppressing MM tumor growth in MM animal models. Thus, Pim-2 may have a pivotal role in tumor progression and bone loss in MM, and Pim-2 inhibition may become an important therapeutic strategy to target the MM cell-bone marrow interaction.Leukemia advance online publication, 30 May 2014; doi:10.1038/leu.2014.147.","ja":"Pim-2 kinase is overexpressed in multiple myeloma (MM) cells to enhance their growth and survival, and regarded as a novel therapeutic target in MM. However, the impact of Pim-2 inhibition on bone disease in MM remains unknown. We demonstrated here that Pim-2 expression was also upregulated in bone marrow stromal cells and MC3T3-E1 preosteoblastic cells in the presence of cytokines known as the inhibitors of osteoblastogenesis in MM, including interleukin-3 (IL-3), IL-7, tumor necrosis factor-, transforming growth factor- (TGF-) and activin A, as well as MM cell conditioned media. The enforced expression of Pim-2 abrogated in vitro osteoblastogenesis by BMP-2, which suggested Pim-2 as a negative regulator for osteoblastogenesis. Treatment with Pim-2 short-interference RNA as well as the Pim inhibitor SMI-16a successfully restored osteoblastogenesis suppressed by all the above inhibitory factors and MM cells. The SMI-16a treatment potentiated BMP-2-mediated anabolic signaling while suppressing TGF- signaling. Furthermore, treatment with the newly synthesized thiazolidine-2,4-dione congener, 12a-OH, as well as its prototypic SMI-16a effectively prevented bone destruction while suppressing MM tumor growth in MM animal models. Thus, Pim-2 may have a pivotal role in tumor progression and bone loss in MM, and Pim-2 inhibition may become an important therapeutic strategy to target the MM cell-bone marrow interaction.Leukemia advance online publication, 30 May 2014; doi:10.1038/leu.2014.147."},"publication_date":"2014-05-02","publication_name":{"en":"Leukemia","ja":"Leukemia"},"languages":["eng"],"referee":true,"identifiers":{"doi":["10.1038/leu.2014.147"],"issn":["1476-5551"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:14, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/24090874","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84884959362&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=272706","label":"url"}],"paper_title":{"en":"Fabrications of zinc-releasing biocement combining zinc calcium phosphate to calcium phosphate cement.","ja":"Fabrications of zinc-releasing biocement combining zinc calcium phosphate to calcium phosphate cement."},"authors":{"en":[{"name":"Horiuchi Shinya"},{"name":"Hiasa Masahiro"},{"name":"Yasue Akihiro"},{"name":"Sekine Kazumitsu"},{"name":"Hamada Kenichi"},{"name":"Asaoka Kenzo"},{"name":"Tanaka Eiji"}],"ja":[{"name":"堀内 信也"},{"name":"日浅 雅博"},{"name":"泰江 章博"},{"name":"関根 一光"},{"name":"浜田 賢一"},{"name":"淺岡 憲三"},{"name":"田中 栄二"}]},"description":{"en":"Recently, zinc-releasing bioceramics have been the focus of much attention owing to their bone-forming ability. Thus, some types of zinc-containing calcium phosphate (e.g., zinc-doped tricalcium phosphate and zinc-substituted hydroxyapatite) are examined and their osteoblastic cell responses determined. In this investigation, we studied the effects of zinc calcium phosphate (ZCP) derived from zinc phosphate incorporated into calcium phosphate cement (CPC) in terms of its setting reaction and MC3T3-E1 osteoblast-like cell responses. Compositional analysis by powder X-ray diffraction analysis revealed that HAP crystals were precipitated in the CPC containing 10 or 30wt% ZCP after successfully hardening. However, the crystal growth observed by scanning electron microscopy was delayed in the presence of additional ZCP. These findings indicate that the additional zinc inhibits crystal growth and the conversion of CPC to the HAP crystals. The proliferation of the cells and alkaline phosphatase (ALP) activity were enhanced when 10wt% ZCP was added to CPC. Taken together, ZCP added CPC at an appropriate fraction has a potent promotional effect on bone substitute biomaterials.","ja":"Recently, zinc-releasing bioceramics have been the focus of much attention owing to their bone-forming ability. Thus, some types of zinc-containing calcium phosphate (e.g., zinc-doped tricalcium phosphate and zinc-substituted hydroxyapatite) are examined and their osteoblastic cell responses determined. In this investigation, we studied the effects of zinc calcium phosphate (ZCP) derived from zinc phosphate incorporated into calcium phosphate cement (CPC) in terms of its setting reaction and MC3T3-E1 osteoblast-like cell responses. Compositional analysis by powder X-ray diffraction analysis revealed that HAP crystals were precipitated in the CPC containing 10 or 30wt% ZCP after successfully hardening. However, the crystal growth observed by scanning electron microscopy was delayed in the presence of additional ZCP. These findings indicate that the additional zinc inhibits crystal growth and the conversion of CPC to the HAP crystals. The proliferation of the cells and alkaline phosphatase (ALP) activity were enhanced when 10wt% ZCP was added to CPC. Taken together, ZCP added CPC at an appropriate fraction has a potent promotional effect on bone substitute biomaterials."},"publication_date":"2014-01","publication_name":{"en":"Journal of the Mechanical Behavior of Biomedical Materials","ja":"Journal of the Mechanical Behavior of Biomedical Materials"},"volume":"Vol.29C","starting_page":"151","ending_page":"160","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jmbbm.2013.09.005"],"issn":["1878-0180"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:15, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=280460","label":"url"}],"paper_title":{"en":"MRI対応生体内金属の開発","ja":"MRI対応生体内金属の開発"},"authors":{"en":[{"name":"Honda Eiichi"},{"name":"Hamada Kenichi"},{"name":"倉林 亨"},{"name":"Takegawa Emi"},{"name":"Yoshida Midori"}],"ja":[{"name":"誉田 栄一"},{"name":"浜田 賢一"},{"name":"倉林 亨"},{"name":"武川 恵美"},{"name":"吉田 みどり"}]},"publication_date":"2013-12-01","publication_name":{"en":"The Journal of the Japanese Society of Magnetic Applications in Dentistry","ja":"日本磁気歯科学会雑誌"},"volume":"Vol.22","number":"No.1","starting_page":"41","ending_page":"48","languages":["jpn"],"referee":true,"identifiers":{"issn":["0918-9629"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:16, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=263721","label":"url"}],"paper_title":{"en":"Magnetic susceptibility and hardness of Au-xPt-yNb alloys for biomedical applications","ja":"Magnetic susceptibility and hardness of Au-xPt-yNb alloys for biomedical applications"},"authors":{"en":[{"name":"Takegawa Emi"},{"name":"Inui Shihoko"},{"name":"Hamada Kenichi"},{"name":"Honda Eiichi"},{"name":"Asaoka Kenzo"}],"ja":[{"name":"武川 恵美"},{"name":"乾 志帆子"},{"name":"浜田 賢一"},{"name":"誉田 栄一"},{"name":"淺岡 憲三"}]},"publication_date":"2013-08-13","publication_name":{"en":"Acta Biomaterialia","ja":"Acta Biomaterialia"},"volume":"Vol.9","starting_page":"8449","ending_page":"8453","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.actbio.2013.05.028"],"issn":["1742-7061"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:17, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/24109823","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=283925","label":"url"}],"paper_title":{"en":"Evaluation of strontium introduced apatite cement as the injectable bone substitute developments.","ja":"Evaluation of strontium introduced apatite cement as the injectable bone substitute developments."},"authors":{"en":[{"name":"Sekine Kazumitsu"},{"name":"Sakama Minoru"},{"name":"Hamada Kenichi"}],"ja":[{"name":"関根 一光"},{"name":"阪間 稔"},{"name":"浜田 賢一"}]},"description":{"en":"We have developed bone cement introducing Strontium (Sr) to promote early bone regeneration. To prolong the release duration of Sr, we applied inorganic Sr filler for containing into the cement powder. The purpose of this study is to evaluate the mechanical properties, crystallinic properties, and ion release activities, especially Sr anion, of this cement. Alpha-TCP powder was mixed with Sr filler, with 0.1wt%, 0.5wt%, 1.0wt%, and 5.0wt%. These were mixed with mixing liquid and formed for each test. They were incubated and crystalized in 95% moisture for 1 week. The mechanical properties were studied by the compression, the diametral tensile strength and 4-point vending. Tested specimens were evaluated by X-ray diffraction(XRD) and scanning electron microscopic(SEM) imaging. The ion release behaviors were measured by inductively coupled plasma mass spectrometry(ICP-MS). The mechanical properties were increased in consistency of filler, but decreased in some samples because of declining the apatite matrix. And the Sr release showed interesting results as the sequential resource of Sr. By adjusting the mixing ratio or considering the application of these Sr releasable cements, this material would show good performance by its strength and longer Sr release for bone regeneration.","ja":"We have developed bone cement introducing Strontium (Sr) to promote early bone regeneration. To prolong the release duration of Sr, we applied inorganic Sr filler for containing into the cement powder. The purpose of this study is to evaluate the mechanical properties, crystallinic properties, and ion release activities, especially Sr anion, of this cement. Alpha-TCP powder was mixed with Sr filler, with 0.1wt%, 0.5wt%, 1.0wt%, and 5.0wt%. These were mixed with mixing liquid and formed for each test. They were incubated and crystalized in 95% moisture for 1 week. The mechanical properties were studied by the compression, the diametral tensile strength and 4-point vending. Tested specimens were evaluated by X-ray diffraction(XRD) and scanning electron microscopic(SEM) imaging. The ion release behaviors were measured by inductively coupled plasma mass spectrometry(ICP-MS). The mechanical properties were increased in consistency of filler, but decreased in some samples because of declining the apatite matrix. And the Sr release showed interesting results as the sequential resource of Sr. By adjusting the mixing ratio or considering the application of these Sr releasable cements, this material would show good performance by its strength and longer Sr release for bone regeneration."},"publication_date":"2013-07-26","publication_name":{"en":"Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society","ja":"Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society"},"volume":"Vol.2013 35th","starting_page":"858","ending_page":"861","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1109/EMBC.2013.6609636"],"issn":["1557-170X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:18, {"insert":{"user_id":"1000242796","type":"published_papers","id":"30550704"},"force":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/23559484","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-84880509056&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=263722","label":"url"}],"paper_title":{"en":"Formability and mechanical properties of porous titanium produced by a moldless process","ja":"Formability and mechanical properties of porous titanium produced by a moldless process"},"authors":{"en":[{"name":"Naitou Yoshihito"},{"name":"Be Jiyon"},{"name":"Tomotake Yoritoki"},{"name":"Hamada Kenichi"},{"name":"Asaoka Kenzo"},{"name":"Ichikawa Tetsuo"}],"ja":[{"name":"内藤 禎人"},{"name":"裵 志英"},{"name":"友竹 偉則"},{"name":"浜田 賢一"},{"name":"淺岡 憲三"},{"name":"市川 哲雄"}]},"description":{"en":"Tailor-made porous titanium implants show great promise in both orthopedic and dental applications. However, traditional powder metallurgical processes require a high-cost mold, making them economically unviable for producing unique devices. In this study, a mixture of titanium powder and an inlay wax binder was developed for moldless forming and sintering. The formability of the mixture, the dimensional changes after sintering, and the physical and mechanical properties of the sintered porous titanium were evaluated. A 90:10 wt % mixture of Ti powder and wax binder was created manually at 70°C. After debindering, the specimen was sintered in Ar at 1100°C without any mold for 1, 5, and 10 h. The shrinkage, porosity, absorption ratio, bending and compressive strength, and elastic modulus were measured. The bending strength (135-356 MPa), compression strength (178-1226 MPa), and elastic modulus (24-54 GPa) increased with sintering time; the shrinkage also increased, whereas the porosity (from 37.1 to 29.7%) and absorption ratio decreased. The high formability of the binder/metal powder mixture presents a clear advantage for fabricating tailor-made bone and hard tissue substitution units. Moreover, the sintered compacts showed high strength and an elastic modulus comparable to that of cortical bone.","ja":"Tailor-made porous titanium implants show great promise in both orthopedic and dental applications. However, traditional powder metallurgical processes require a high-cost mold, making them economically unviable for producing unique devices. In this study, a mixture of titanium powder and an inlay wax binder was developed for moldless forming and sintering. The formability of the mixture, the dimensional changes after sintering, and the physical and mechanical properties of the sintered porous titanium were evaluated. A 90:10 wt % mixture of Ti powder and wax binder was created manually at 70°C. After debindering, the specimen was sintered in Ar at 1100°C without any mold for 1, 5, and 10 h. The shrinkage, porosity, absorption ratio, bending and compressive strength, and elastic modulus were measured. The bending strength (135-356 MPa), compression strength (178-1226 MPa), and elastic modulus (24-54 GPa) increased with sintering time; the shrinkage also increased, whereas the porosity (from 37.1 to 29.7%) and absorption ratio decreased. The high formability of the binder/metal powder mixture presents a clear advantage for fabricating tailor-made bone and hard tissue substitution units. Moreover, the sintered compacts showed high strength and an elastic modulus comparable to that of cortical bone."},"publication_date":"2013-06","publication_name":{"en":"Journal of Biomedical Materials Research. Part B, Applied Biomaterials","ja":"Journal of Biomedical Materials Research. Part B, Applied Biomaterials"},"volume":"Vol.101","number":"No.6","starting_page":"1090","ending_page":"1094","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1002/jbm.b.32919"],"issn":["1552-4981"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:19, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/21751834","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=241851","label":"url"}],"paper_title":{"en":"Reinforcement of bond strength of self-etching orthodontic adhesive.","ja":"Reinforcement of bond strength of self-etching orthodontic adhesive."},"authors":{"en":[{"name":"Horiuchi Shinya"},{"name":"Kuroda Shingo"},{"name":"Hiasa Masahiro"},{"name":"Suge Toshiyuki"},{"name":"Saku Seitaro"},{"name":"Hamada Kenichi"},{"name":"Matsuo Takashi"},{"name":"Asaoka Kenzo"},{"name":"Tanaka Eiji"}],"ja":[{"name":"堀内 信也"},{"name":"黒田 晋吾"},{"name":"日浅 雅博"},{"name":"菅 俊行"},{"name":"Saku Seitaro"},{"name":"浜田 賢一"},{"name":"松尾 敬志"},{"name":"淺岡 憲三"},{"name":"田中 栄二"}]},"description":{"en":"Abstract Objective: To determine the reinforcement of bond strength of a self-etching system by applying a pretreatment agent. Materials and Methods: Sixty extracted human premolars were used in this study. The enamel surfaces were treated with four pretreatment agents?phosphoric acid, polyacrylic acid, citric acid, and ammonium hexafluorosilicate (SiF)?and were examined under a scanning electron microscope. Afterward, orthodontic brackets were bonded with a self-etching adhesive system (n ?=? 10 for each agent), and shear bond strength was measured through a debonding process. The adhesive remnant index (ARI) was also assessed. Results: Enamel surfaces treated with polyacrylic acid seemed almost the same as intact enamel. Treatment with SiF induced slight shallow depressions compared with the intact enamel. On the other hand, enamel surfaces treated with citric acid and phosphoric acid showed severe etching patterns. All pretreatments increased the bond strength, but SiF-treated specimens revealed the greatest strength (12.201 ? 1.048?MPa), followed by polyacrylic acid (12.030 ? 2.103?MPa). The control group with no pretreatment showed the least strength (9.078 ? 1.678?MPa). All pretreatments increased ARI score compared with the control group. Conclusions: Surface conditioning before bracket adhesion could reinforce the bond strength of the self-etching adhesive system, resulting in a more reliable bonding system.","ja":"Abstract Objective: To determine the reinforcement of bond strength of a self-etching system by applying a pretreatment agent. Materials and Methods: Sixty extracted human premolars were used in this study. The enamel surfaces were treated with four pretreatment agents?phosphoric acid, polyacrylic acid, citric acid, and ammonium hexafluorosilicate (SiF)?and were examined under a scanning electron microscope. Afterward, orthodontic brackets were bonded with a self-etching adhesive system (n ?=? 10 for each agent), and shear bond strength was measured through a debonding process. The adhesive remnant index (ARI) was also assessed. Results: Enamel surfaces treated with polyacrylic acid seemed almost the same as intact enamel. Treatment with SiF induced slight shallow depressions compared with the intact enamel. On the other hand, enamel surfaces treated with citric acid and phosphoric acid showed severe etching patterns. All pretreatments increased the bond strength, but SiF-treated specimens revealed the greatest strength (12.201 ? 1.048?MPa), followed by polyacrylic acid (12.030 ? 2.103?MPa). The control group with no pretreatment showed the least strength (9.078 ? 1.678?MPa). All pretreatments increased ARI score compared with the control group. Conclusions: Surface conditioning before bracket adhesion could reinforce the bond strength of the self-etching adhesive system, resulting in a more reliable bonding system."},"publication_date":"2011-07-13","publication_name":{"en":"The Angle Orthodontist","ja":"The Angle Orthodontist"},"volume":"Vol.82","number":"No.1","starting_page":"30","ending_page":"35","languages":["eng"],"referee":true,"identifiers":{"doi":["10.2319/012011-39.1"],"issn":["1945-7103"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:20, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/20379030","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=209315","label":"url"}],"paper_title":{"en":"Antibacterial activity of composite resin with glass-ionomer filler particles","ja":"Antibacterial activity of composite resin with glass-ionomer filler particles"},"authors":{"en":[{"name":"Saku Seitaro"},{"name":"Kotake Hirotomo"},{"name":"Scougall Vilchis RJ"},{"name":"Ohashi Shizue"},{"name":"Hotta Masato"},{"name":"Horiuchi Shinya"},{"name":"Hamada Kenichi"},{"name":"Asaoka Kenzo"},{"name":"Tanaka Eiji"},{"name":"Yamamoto Kohji"}],"ja":[{"name":"Saku Seitaro"},{"name":"Kotake Hirotomo"},{"name":"Scougall Vilchis RJ"},{"name":"Ohashi Shizue"},{"name":"Hotta Masato"},{"name":"堀内 信也"},{"name":"浜田 賢一"},{"name":"淺岡 憲三"},{"name":"田中 栄二"},{"name":"Yamamoto Kohji"}]},"description":{"en":"The purpose of this study was to examine the antibacterial activity of composite resin with glass-ionomer filler particles versus that of contemporary commercial composite resins. Three composite resins were used: Beautifil II (containing S-PRG filler), Clearfil AP-X, and Filtek Z250. Resin blocks were bonded to maxillary first molars, and plaque accumulation on the resin block surface was examined after 8 hours. For the antibacterial test, the number of Streptococcus mutans in contact with the composite resin blocks after incubation for 12 hours was determined, and adherence of radiolabeled bacteria was evaluated. Less dental plaque was formed on Beautifil II resin block as compared to the other two materials. Antibacterial test revealed that there were no significant differences in the number of Streptococcus mutans among the three composite resins. However, the adherence of radiolabeled bacteria to the saliva-treated resin surface was significantly (p>0.01) lower in Beautifil II than in the other two materials. These results suggested that Beautifil II could reduce dental plaque formation and bacterial adherence, leading to prevention of secondary caries","ja":"The purpose of this study was to examine the antibacterial activity of composite resin with glass-ionomer filler particles versus that of contemporary commercial composite resins. Three composite resins were used: Beautifil II (containing S-PRG filler), Clearfil AP-X, and Filtek Z250. Resin blocks were bonded to maxillary first molars, and plaque accumulation on the resin block surface was examined after 8 hours. For the antibacterial test, the number of Streptococcus mutans in contact with the composite resin blocks after incubation for 12 hours was determined, and adherence of radiolabeled bacteria was evaluated. Less dental plaque was formed on Beautifil II resin block as compared to the other two materials. Antibacterial test revealed that there were no significant differences in the number of Streptococcus mutans among the three composite resins. However, the adherence of radiolabeled bacteria to the saliva-treated resin surface was significantly (p>0.01) lower in Beautifil II than in the other two materials. These results suggested that Beautifil II could reduce dental plaque formation and bacterial adherence, leading to prevention of secondary caries"},"publication_date":"2010-03","publication_name":{"en":"Dental Materials Journal","ja":"Dental Materials Journal"},"volume":"Vol.29","number":"No.2","starting_page":"193","ending_page":"198","languages":["eng"],"referee":true,"identifiers":{"doi":["10.4012/dmj.2009-050"],"issn":["0287-4547"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:21, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/19721278","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=193614","label":"url"}],"paper_title":{"en":"Enamel bonding of self-etching and phosphoric acid-etching orthodontic adhesives in simulated clinical conditions: Debonding force and enamel surface","ja":"Enamel bonding of self-etching and phosphoric acid-etching orthodontic adhesives in simulated clinical conditions: Debonding force and enamel surface"},"authors":{"en":[{"name":"Horiuchi Shinya"},{"name":"Kaneko Kazuyuki"},{"name":"Mori H"},{"name":"Kawakami Emi"},{"name":"Tsukahara T"},{"name":"Yamamoto K"},{"name":"Hamada Kenichi"},{"name":"Asaoka Kenzo"},{"name":"Tanaka Eiji"}],"ja":[{"name":"堀内 信也"},{"name":"金子 和之"},{"name":"Mori H"},{"name":"川上 恵実"},{"name":"Tsukahara T"},{"name":"Yamamoto K"},{"name":"浜田 賢一"},{"name":"淺岡 憲三"},{"name":"田中 栄二"}]},"description":{"en":"This study aimed to evaluate the effectiveness of self-etching and phosphoric acid-etching orthodontic adhesives for enamel bonding in simulated clinical conditions. By using two self-etching (Transbond Plus, TP; Beauty Ortho Bond, BB) and two acid-etching (Transbond XT, TX; Superbond Orthomite, SB) adhesives, orthodontic brackets were bonded on human premolars (n=10 for each adhesive). Ten teeth without bracket bonding, i.e., intact enamel surfaces, were used as control for SEM observation. After 7-day storage in lactic acid solution, bracket debonding force by means of debonding pliers, adhesive remnant index (ARI), and enamel surface morphology were examined. All the tested adhesives exhibited sufficient bond strength for clinical use. The ARI scores were almost the same among the four adhesives. In terms of SEM observation, the enamel surfaces in the control and TP groups showed a slight change after immersion in lactic acid solution, while the BB group showed less change on the enamel surface compared with the TP group. Meanwhile, the two acid-etching adhesives caused considerable demineralization. Taken together, these findings indicated that the action of self-etching systems was evidently more conservative.","ja":"This study aimed to evaluate the effectiveness of self-etching and phosphoric acid-etching orthodontic adhesives for enamel bonding in simulated clinical conditions. By using two self-etching (Transbond Plus, TP; Beauty Ortho Bond, BB) and two acid-etching (Transbond XT, TX; Superbond Orthomite, SB) adhesives, orthodontic brackets were bonded on human premolars (n=10 for each adhesive). Ten teeth without bracket bonding, i.e., intact enamel surfaces, were used as control for SEM observation. After 7-day storage in lactic acid solution, bracket debonding force by means of debonding pliers, adhesive remnant index (ARI), and enamel surface morphology were examined. All the tested adhesives exhibited sufficient bond strength for clinical use. The ARI scores were almost the same among the four adhesives. In terms of SEM observation, the enamel surfaces in the control and TP groups showed a slight change after immersion in lactic acid solution, while the BB group showed less change on the enamel surface compared with the TP group. Meanwhile, the two acid-etching adhesives caused considerable demineralization. Taken together, these findings indicated that the action of self-etching systems was evidently more conservative."},"publication_date":"2009-07","publication_name":{"en":"Dental Materials Journal","ja":"Dental Materials Journal"},"volume":"Vol.28","number":"No.4","starting_page":"419","ending_page":"425","languages":["eng"],"referee":true,"identifiers":{"doi":["10.4012/dmj.28.419"],"issn":["0287-4547"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:22, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/19581714","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=193529","label":"url"}],"paper_title":{"en":"Effects of heat treatment on the bioactivity of surface-modified titanium in calcium solution","ja":"Effects of heat treatment on the bioactivity of surface-modified titanium in calcium solution"},"authors":{"en":[{"name":"Sultana Razia"},{"name":"Hamada Kenichi"},{"name":"Ichikawa Tetsuo"},{"name":"Asaoka Kenzo"}],"ja":[{"name":"Sultana Razia"},{"name":"浜田 賢一"},{"name":"市川 哲雄"},{"name":"淺岡 憲三"}]},"description":{"en":"The purpose of this study was to determine the effects of heat treatment on the bioactivity of hydrothermal-modified titanium in CaO solution for improved bioactivity by immersion in simulated body fluid (SBF). The hydrothermal treatment of titanium in CaO solution was performed at 121 degrees C at 0.2 MPa for 1 h in an autoclave followed by 1 h heat treatments at 200, 400, 600 and 800 degrees C simultaneously. The bioactivity of titanium was evaluated by hydroxyapatite precipitation during immersion in SBF. Surface microstructure changes after the heat treatments and immersion in SBF were determined by X-ray diffractometry (XRD), X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy (SEM). Heat treatments at high temperatures (600 and 800 degrees C) promoted the synthesis of anatase, increased the thickness of the titanium oxide layer on the modified titanium surface and promoted the synthesis of calcium titanate, which possibly promoted the precipitation of apatite in SBF. The extent of precipitations increased with the time of immersion in SBF and the temperature of the heat treatment. Island-like deposits of needle-like crystals were observed only on the surface of the 600 and 800 degrees C heat-treated specimens after two or four week immersions in SBF. The results suggested that treatments of the surface of hydrothermal-treated titanium specimens at high temperatures (600 and 800 degrees C) could be effective for the surface modification of titanium as an implant material offering better osseointegration.","ja":"The purpose of this study was to determine the effects of heat treatment on the bioactivity of hydrothermal-modified titanium in CaO solution for improved bioactivity by immersion in simulated body fluid (SBF). The hydrothermal treatment of titanium in CaO solution was performed at 121 degrees C at 0.2 MPa for 1 h in an autoclave followed by 1 h heat treatments at 200, 400, 600 and 800 degrees C simultaneously. The bioactivity of titanium was evaluated by hydroxyapatite precipitation during immersion in SBF. Surface microstructure changes after the heat treatments and immersion in SBF were determined by X-ray diffractometry (XRD), X-ray photoelectron spectroscopy (XPS), and scanning electron microscopy (SEM). Heat treatments at high temperatures (600 and 800 degrees C) promoted the synthesis of anatase, increased the thickness of the titanium oxide layer on the modified titanium surface and promoted the synthesis of calcium titanate, which possibly promoted the precipitation of apatite in SBF. The extent of precipitations increased with the time of immersion in SBF and the temperature of the heat treatment. Island-like deposits of needle-like crystals were observed only on the surface of the 600 and 800 degrees C heat-treated specimens after two or four week immersions in SBF. The results suggested that treatments of the surface of hydrothermal-treated titanium specimens at high temperatures (600 and 800 degrees C) could be effective for the surface modification of titanium as an implant material offering better osseointegration."},"publication_date":"2009-07","publication_name":{"en":"Bio-Medical Materials and Engineering","ja":"Bio-Medical Materials and Engineering"},"volume":"Vol.19","number":"No.2-3","starting_page":"193","ending_page":"204","languages":["eng"],"referee":true,"identifiers":{"doi":["10.3233/BME-2008-0580"],"issn":["0959-2989"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:23, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=148045","label":"url"}],"paper_title":{"en":"Effects of ternary additions on martensitic transformation of TiAu","ja":"Effects of ternary additions on martensitic transformation of TiAu"},"authors":{"en":[{"name":"Kawamura, T."},{"name":"Tachi, R."},{"name":"Inamura, T."},{"name":"Hosoda, H."},{"name":"Wakashima, K."},{"name":"Hamada Kenichi"},{"name":"Miyazaki, S."}],"ja":[{"name":"Kawamura, T."},{"name":"Tachi, R."},{"name":"Inamura, T."},{"name":"Hosoda, H."},{"name":"Wakashima, K."},{"name":"浜田 賢一"},{"name":"Miyazaki, S."}]},"publication_date":"2006-11","publication_name":{"en":"Materials Science and Engineering A","ja":"Materials Science and Engineering A"},"volume":"Vol.438-440","starting_page":"383","ending_page":"386","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.msea.2006.01.123"],"issn":["0921-5093"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:24, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/40006892626/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520009409490024320/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=126446","label":"url"}],"paper_title":{"en":"TiNi形状記憶合金ワイヤ強化Mg合金基複合材料の組織と機械的性質","ja":"TiNi形状記憶合金ワイヤ強化Mg合金基複合材料の組織と機械的性質"},"authors":{"en":[{"name":"水内 潔"},{"name":"井上 漢龍"},{"name":"杉岡 正美"},{"name":"伊丹 正郎"},{"name":"Hamada Kenichi"},{"name":"川原 正和"}],"ja":[{"name":"水内 潔"},{"name":"井上 漢龍"},{"name":"杉岡 正美"},{"name":"伊丹 正郎"},{"name":"浜田 賢一"},{"name":"川原 正和"}]},"publication_date":"2005-08-01","publication_name":{"en":"Journal of the Japan Institute Metals","ja":"日本金属学会誌"},"volume":"Vol.69","number":"No.8","starting_page":"608","ending_page":"613","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.2320/jinstmet.69.608"],"issn":["0021-4876"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:25, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://cir.nii.ac.jp/crid/1570291226806903424/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=126447","label":"url"}],"paper_title":{"en":"Processing of TiNi SMA fiber reinforced AZ31 Mg alloy matrix composite by pulsed current hot pressing","ja":"Processing of TiNi SMA fiber reinforced AZ31 Mg alloy matrix composite by pulsed current hot pressing"},"authors":{"en":[{"name":"Mizuuchi Kiyoshi"},{"name":"Inoue Kanryu"},{"name":"Hamada Kenichi"},{"name":"Sugioka Masami"},{"name":"Itami Masao"},{"name":"Fukusumi M"},{"name":"Kawahara M"}],"ja":[{"name":"Mizuuchi Kiyoshi"},{"name":"Inoue Kanryu"},{"name":"浜田 賢一"},{"name":"Sugioka Masami"},{"name":"Itami Masao"},{"name":"Fukusumi M"},{"name":"Kawahara M"}]},"publication_date":"2004-01-01","publication_name":{"en":"Materials Science and Engineering A","ja":"Materials Science and Engineering A"},"volume":"Vol.367","number":"No.1-2","starting_page":"343","ending_page":"349","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.msea.2003.10.286"],"issn":["0921-5093"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
line:26, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12873119","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001204717659136/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0141448733&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=78626","label":"url"}],"paper_title":{"en":"Shape recovery of shape memory alloy fiber embedded resin matrix smart composite after crack repair","ja":"Shape recovery of shape memory alloy fiber embedded resin matrix smart composite after crack repair"},"authors":{"en":[{"name":"Hamada Kenichi"},{"name":"Kawano Fumiaki"},{"name":"Asaoka Kenzo"}],"ja":[{"name":"浜田 賢一"},{"name":"河野 文昭"},{"name":"淺岡 憲三"}]},"description":{"en":"Ni-Ti shape memory alloy fiber embedded resin matrix composites were produced for evaluation of \"smart denture\", a newly developing denture with the function to close its own crack. Their bending strength and shape recovery after instant crack repair was estimated. The embedded fibers did not decrease the bending strength of the composite after repair. The crack closure of the composites was performed well simply by heating at 80 degrees C. Nevertheless, they showed apparent deflection after crack repair. The following two phenomena were supposed to be the main cause of it: the polymerization shrinkage of matrix resin with heating, and the coefficient of the thermal expansion mismatch between the fiber and the matrix. The embedded fibers could close the crack of the matrix with enough high accuracy for specimen repair, but they turned out to change the specimen shape after repair.","ja":"Ni-Ti shape memory alloy fiber embedded resin matrix composites were produced for evaluation of \"smart denture\", a newly developing denture with the function to close its own crack. Their bending strength and shape recovery after instant crack repair was estimated. The embedded fibers did not decrease the bending strength of the composite after repair. The crack closure of the composites was performed well simply by heating at 80 degrees C. Nevertheless, they showed apparent deflection after crack repair. The following two phenomena were supposed to be the main cause of it: the polymerization shrinkage of matrix resin with heating, and the coefficient of the thermal expansion mismatch between the fiber and the matrix. The embedded fibers could close the crack of the matrix with enough high accuracy for specimen repair, but they turned out to change the specimen shape after repair."},"publication_date":"2003-06","publication_name":{"en":"Dental Materials Journal","ja":"Dental Materials Journal"},"volume":"Vol.22","number":"No.2","starting_page":"160","ending_page":"167","languages":["eng"],"referee":true,"identifiers":{"doi":["10.4012/dmj.22.160"],"issn":["0287-4547"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
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line:29, {"insert":{"user_id":"1000242796","type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11962668","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=71188","label":"url"}],"paper_title":{"en":"Hydrothermal modification of titanium surface in calcium solutions","ja":"Hydrothermal modification of titanium surface in calcium solutions"},"authors":{"en":[{"name":"Hamada Kenichi"},{"name":"Kon Masayuki"},{"name":"Hanawa Takao"},{"name":"Yokoyama Ken'ichi"},{"name":"Miyamoto Youji"},{"name":"Asaoka Kenzo"}],"ja":[{"name":"浜田 賢一"},{"name":"今 政幸"},{"name":"塙 隆夫"},{"name":"横山 賢一"},{"name":"宮本 洋二"},{"name":"淺岡 憲三"}]},"description":{"en":"Hydrothermal modification of a titanium surface in calcium solutions was performed. The apatite precipitation on the modified surface in Hanks' solution, as a simulated body fluid, was evaluated and the surface microstructure changes after the modification were characterized by thin-film X-ray diffractometry (TF-XRD) and X-ray photoelectron spectroscopy (XPS). Hydrothermal modification in CaO solution enhanced the precipitation of apatite on the titanium surface. High pH, high pressure and high temperature of the CaO solution increased the thickness of the surface-modified layer and enhanced the synthesis of calcium titanate which possibly promoted the precipitation of apatite in Hanks' solution. Hydrothermal modification in CaCl2 solution, on the other hand, showed reverse effects. The modification of titanium in CaO solution with hydrothermal treatment is expected to result in excellent osteointegration and can be easily performed by using an autoclave, a clinical apparatus widely used.","ja":"Hydrothermal modification of a titanium surface in calcium solutions was performed. The apatite precipitation on the modified surface in Hanks' solution, as a simulated body fluid, was evaluated and the surface microstructure changes after the modification were characterized by thin-film X-ray diffractometry (TF-XRD) and X-ray photoelectron spectroscopy (XPS). Hydrothermal modification in CaO solution enhanced the precipitation of apatite on the titanium surface. High pH, high pressure and high temperature of the CaO solution increased the thickness of the surface-modified layer and enhanced the synthesis of calcium titanate which possibly promoted the precipitation of apatite in Hanks' solution. Hydrothermal modification in CaCl2 solution, on the other hand, showed reverse effects. The modification of titanium in CaO solution with hydrothermal treatment is expected to result in excellent osteointegration and can be easily performed by using an autoclave, a clinical apparatus widely used."},"publication_date":"2002-05","publication_name":{"en":"Biomaterials","ja":"Biomaterials"},"volume":"Vol.23","number":"No.10","starting_page":"2265","ending_page":"2272","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0142-9612(01)00361-1"],"issn":["0142-9612"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
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line:1, {"insert":{"user_id":"1000242796","type":"misc"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=407718","label":"url"}],"paper_title":{"en":"MRIアーチファクトフリー生体医療用合金の開発","ja":"MRIアーチファクトフリー生体医療用合金の開発"},"authors":{"en":[{"name":"Takegawa Emi"},{"name":"Hamada Kenichi"}],"ja":[{"name":"武川 恵美"},{"name":"浜田 賢一"}]},"publication_date":"2022-09-25","publication_name":{"en":"The Journal of Dental Engineering","ja":"The Journal of Dental Engineering"},"volume":"Vol.41","number":"No.3","starting_page":"215","ending_page":"218","languages":["jpn"],"invited":true,"misc_type":"introduction_scientific_journal"},"priority":"input_data"}
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line:9, {"insert":{"user_id":"1000242796","type":"misc","id":"23817435"},"force":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/110002990638/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390282763026533888/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=78632","label":"url"}],"paper_title":{"en":"Material Design of Denture Base Resin Reinforced by Shape Memory Alloy Fiber","ja":"形状記憶合金繊維で強化した床用レジンの材料設計"},"authors":{"en":[{"name":"Hamada Kenichi"},{"name":"Kawano Fumiaki"},{"name":"Asaoka Kenzo"}],"ja":[{"name":"浜田 賢一"},{"name":"河野 文昭"},{"name":"淺岡 憲三"}]},"description":{"en":"We evaluated the tensile strength of denture base resin reinforced by shape memory alloy fiber. Fiber surface treatment with primer decreased the fiber-pull-out in a shape-memory-fiber reinforced denture base resin matrix composite and increased the tensile strength. We speculated that the increase in tensile strength was caused by an increase in interfacial strength between the fiber and the matrix. Since heat treatment at above 60℃ increased the composite tensile strength, this composite worked as a smartcomposite. Although there was no effect of heat treatment temperature on tensile strength, flexion of composite was observed after heat treatment at a higher temperature, suggesting that the heat treatment temperature should be lower. We speculated that the slight increase in tensile strength after heat treatment was caused by the higher martensite transformation starting temperature of the fiber.","ja":"形状記憶合金繊維で強化した床用レジンの引張強さについて検討した. 繊維表面のプライマー処理により形状記憶合金繊維強化レジン基複合材料の繊維のプルアウトが減少し, 引張強さが増加した. この引張強さの増加は繊維-マトリックス界面強度の増加によると考えられた. 60℃以上での熱処理によって複合材料の引張強さは若干増加したため, この試料がスマート複合材料として機能していることがわかった. 熱処理温度による引張強さの差は認められなかったが, 高温で熱処理した場合, 複合材料の屈曲が認められたため, 熱処理温度は低くすべきだとわかった. 熱処理後の引張強さがあまり増加しなかった理由は, 繊維マルテンサイト変態開始温度が高いためと考えられた."},"publication_date":"2001-02","publication_name":{"en":"The Journal of the Japanese Society for Dental Materials and Devices","ja":"歯科材料·器械"},"volume":"Vol.20","number":"No.2","starting_page":"131","ending_page":"135","languages":["jpn"],"referee":true,"identifiers":{"issn":["0286-5858"]}},"priority":"input_data"}
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