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en: Characteristics of Oral Dysfunction in Pediatric Patients with Malocclusion

ja: 小児不正咬合患者の小児患者における口腔機能障害の特徴

en: To clarify the characteristics of oral dysfunction in pediatric patients with malocclusion, we compared oral function between individuals with normal occlusion and those with malocclusion.A total of 108 participants, including 41 boys and 67 girls (mean age ± standard deviation, 9.4 ± 2.2 years), were recruited from outpatients who visited the Departments of Orthodontics and Pediatric Dentistry of Tokushima University Hospital. They were classified according to their occlusal status into normal occlusion, crowding, maxillary protrusion, mandibular protrusion, open bite, and others.This study revealed that patients with malocclusion had more functional problems (e.g. tongue thrust, low tongue posture and another oral habits) than subjects with normal occlusion and that the functional problems were associated with various types of malocclusion. Especially, patients with open bite showed the characteristic features of oral function and their maximum lip closure force was significantly weaker than that of subjects with normal occlusion (p < 0.05).We found the characteristic features of oral dysfunction in each malocclusion. It is thought that it is necessary to make an individual training program to the characteristic feature of oral function.

en: Journal of Oral Health and Biosciences

ja: Journal of Oral Health and Biosciences


en: 食道がん化学療法患者に対するがん支持療法としての専門的口腔ケアの有用性

ja: 食道がん化学療法患者に対するがん支持療法としての専門的口腔ケアの有用性

en: Journal of Dental Health

ja: 口腔衛生学会雑誌


en: Relationship among Health Related Quality of Life, Quality of Sleep, and Oral Health Condition

en: Health

ja: Health


en: 徳島県内の回復期病院における看護師の口腔ケアに対する認識ーアンケート調査結果からー

en: Journal of Shikoku Public Health Society

ja: 四国公衆衛生学会雑誌


en: Relationship between Chewing Behavior and Oral Conditions in Elementary School Children Based on the "Chewing 30" Program: An Intervention Study

ja: Journal of Dental Health


en: Problems on oral healthcare in convalescent hospitals : Questionnaire survey for non-dental professionals

ja: 回復期病院職員が抱える口腔ケアについての悩み-他職種へのアンケート調査より-

en: Oral Care

ja: 日本口腔ケア学会雑誌


en: Awareness of oral health management in outpatients undergoing chemotherapy

ja: 外来化学療法患者の口腔健康管理に対する認識


en: Analysis of the educational effect of OSCE performed at the college of dental hygienist course

ja: 歯科衛生士養成校におけるOSCE導入の教育学的効果に関する解析

en: The Journal of Japan Society of Dental Hygiene Education

ja: 日本歯科衛生教育学会雑誌


en: 要介護高齢者の口腔ケアを支援する簡易版アセスメントシートの開発

ja: 要介護高齢者の口腔ケアを支援する簡易版アセスメントシートの開発

en: 日本摂食嚥下リハビリテーション学会誌

ja: 日本摂食嚥下リハビリテーション学会誌


en: The usefulness of advising chart storage system for oral care which utilized cloud computing

ja: クラウドコンピューティングを活用した口腔保健業務支援システムの有用性に関する検討

en: General Rehabilitation

ja: 総合リハビリテーション


en: The usefulness of the educational management network system for promoting "dental education program with community-rearing"

ja: 地域育成型歯学教育を推進するための教育管理ネットワークシステム導入の有用性

ja: 日本歯科衛生教育学会雑誌


en: 地域高齢者との福祉体験学習の教育効果と地域貢献事業としての評価

ja: 地域高齢者との福祉体験学習の教育効果と地域貢献事業としての評価

en: The purose of this study is to evaluate the educational effect by the welfare-experience learning program with aged people in community，and to evaluate this program as the regional contribution. This program is to aim at having a consciousness of becoming the dental professional in the University of Tokushima，Faculty of Dentistry，and they were carried out with 16 institutions (a total of 28 times).This program makes students accompany the oral health guidance"long-life oral healthy classroom"，and they carried out the experience study as on auxiliary person of the variaus functional oral-training for elderly people.By the investigation of the student's report, there are students who recognized the achievement objectives which are roles of the way concerning regional contribution as dental professionals in community. On the other hand，the questionnaire to the participating persoonnel was conducted in order to evalaote this program as the regional contrtbution. As a result，this program is useful to elderly people and the understanding of institution personnel is also deepened this practice. As mentioned above，the result of having is suitable for the educational goal "to have a consciousness of becoming the dental professional". Furthermore，this program was considered that future continuation is also expected by deepening of an understanding to the personnel's functional oral-training program.本研究の目的は，地域高齢者との福祉体験学習における学生への教育効果と，地域貢献事業としての評価をすることである．徳島大学歯学部では，医療人を志すものとしての自覚を持つことを目的とした取り組みを県内16カ所の施設で合計28回実施した．これは，学生が口腔保健指導「お口の健康長寿教室」において，高齢者を対象とした口腔機能訓練の補助者として体験学習するものである．学習後のレポートから， 到達目標とした地域貢献の在り方や歯科専門職としての役割を認識する学生が多くを占めた．一方，地域貢献事業として評価するため，参加職員への調査を行った結果，利用者への役立ちに加え，多くの施設職員の理解も深まったとのアンケート結果が得られた．以上から，本取り組みは学生への教育目標「医療人としての自覚を持つ」に沿った成果が得られており，また，施設職員の口腔機能向上プ口グラムへの盤解の深まりから，今後の継続が期待される．

en: Journal of University Education Research

ja: 大学教育研究ジャーナル


en: 徳島大学パイロット事業支援プログラム「歯科医療系学生の口腔保健・福祉体験実習による健康長寿支援」


en: 教育GP「高齢社会を担う地域育成型歯学教育」(第1報) 高齢者交流学習による教育効果

en: 歯学部1年生22名(口腔保健学科16名，歯学科6名)を対象に，平成20年度に実施した高齢者交流学習の教育効果について考察した．交流前には同施設長より生と死，老いについて特別講義を受け，4回目の交流後及び最終回の交流後にふり返り授業を実施した．交流学習の教育効果については毎回の学習記録と共に自己評価を10点満点で記載させた．養護老人ホームにおいて高齢者との1対1の交流からコミュニケーションを養う交流学習を実施した結果，交流後の学習記録に認められる心に深く感じた内容や自己評価点数の上昇，更に四つの到達目標に沿った表現の記載が参加学生から認められたことから，1年次に実施した取り組みは人間力の向上という一般目標に適した有効な教育カリキュラムであると思われた．

en: Shikoku Dental Research

ja: 四国歯学会雑誌


en: The clinicopathological significance of the expression of CXCR4 protein in oral squamous cell carcinoma

en: We have demonstrated the possibility that the stromal cell-derived factor-1 (SDF-1; CXCL12)/CXCR4 system might be involved in the establishment of lymph node metastasis in oral squamous cell carcinoma (SCC). In order to further clarify the role of the SDF-1/CXCR4 system in oral SCC, we examined the expression of CXCR4 and SDF-1 in biopsy specimens from 61 patients with oral SCC by means of immunohistochemistry, and investigated several clinicopathological factors, including age, sex, lymph node metastasis, invasion, recurrence and prognosis. The expression of CXCR4 and SDF-1 was observed in 57.3 and 11.4% of our subjects, respectively. Although we were unable to find a statistically significant association between the expression of SDF-1 and any clinicopathological factors, we did find a significant association between the expression of CXCR4 and lymph node metastasis (P=0.0417). Moreover, the mode of invasion (P=0.0002) and recurrence of the tumors (P=0.0185) were strongly associated with CXCR4 expression, and the CXCR4-positive group showed a significantly poorer prognosis than the CXCR4-negative group (P=0.0401). Recombinant SDF-1alpha stimulated in vitro invasiveness and scattering in CXCR4-expressing oral SCC cells, but the treatment did not affect the expression of matrix metalloproteinases or urokinase-type plasminogen activator. These results indicate that SDF-1/CXCR4 signaling in oral SCC cells might be involved in the diverse action of oral SCC, including invasion or micrometastasis at the primary site and lymph node metastasis.

en: International Journal of Oncology

ja: International Journal of Oncology


en: Clinical statistical study of jaw deformity patients at the Department of Orthodontics, Tokushima University Dental Hospital

ja: 徳島大学歯学部附属病院矯正歯科における顎変形症患者の臨床統計学的検討


en: パノラマX線画像の視覚評価に関する基礎的検討

ja: パノラマX線画像の視覚評価に関する基礎的検討


en: Therapy for oral squamous cell carcinoma by tegafur and streptococcal agent OK-432 in combination with radiotherapy : Association of the therapeutic effect with differentiation and apoptosis in the cancer cells

en: Twenty patients with oral squamous cell carcinoma having mainly stage II or III lesions without distant metastasis, were treated with tegafur and streptococcal agent, OK-432, in combination with radiotherapy. As a consequence, 16 cases among the treated 20 cases showed complete remission by this therapy alone. Especially, we have found that the squamous cell carcinoma arising in non-keratinizing oral epithelium rather than in keratinizing oral epithelium has better response to this therapy. Among the 16 cases with complete remission (CR) by the current therapy, 10 cases were histopathologically diagnosed as well-differentiated squamous cell carcinoma and six cases as moderately differentiated squamous cell carcinoma. When we examined immunohistochemically the expression of various antigens such as proliferating cell nuclear antigen (PCNA), p53 and LeY or the presence of DNA fragmentation by nick-end labelling in the biopsy materials taken at the first visit to our clinic from 20 patients treated with the current therapy, the CR group showed a significantly increased LeY expres-sion level ( p< 0.05) and DNA fragmentation rate (p< 0.05) as compared with the partial response (PR, n= 3) + no change (NC, n= 1) group. On the other hand, the CR group with respect to PCNA expression level was significantly decreased as compared with the PR + NC group ( p< 0.05). From these findings, it can be considered that the therapy for oral squamous cell carcinoma by UFT and OK-432 in combination with radiotherapy is very effective, which may be associated with differentiation or apoptosis in oral squamous carcinoma cells. In addition, we present the clinical findings and results of immunohistochemical staining for the biopsy materials obtained from four CR cases treated with the current therapeutic method.

en: Apoptosis

ja: Apoptosis


en: Induction of Bone Formation in an Adenoid Cystic Carcinoma of the Maxillary Sinus by Adoptive Immunotherapy Involving Intra-arterial Injection of Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 in Combination with Radiotherapy

en: A patient with an adenoid cystic carcinoma of the maxillary sinus was treated by adoptive immunotherapy involving intra-arterial injection of lymphokine-activated killer cells (a total number of 7 x 10(7) cells) and recombinant interleukin-2 (a total dose of 2.75 x 10(7) units) in combination with radiotherapy (60Co; total irradiation dose of 5,000 rads). Consequently, it was found that bone formation was induced in the treated tumor, which was then replaced completely by lamellar bone tissue with myxomatous stroma. This finding indicates that the tumor cells composing certain adenoid cystic carcinoma can be converted into normal-appearing, bone-forming cells by current therapy and this differentiation phenomenon leads to cure of the tumor.

en: Journal of Biological Response Modifiers


en: シラバスにおける医療関係専門職が学ぶ口腔ケア関連科目について― シラバスによる教育内容の調査 ―

en: Oral Care


en: A Report of Activity in a Short-term Study Abroad to Helsinki Metropolia University of Applied Sciences

ja: ヘルシンキ・メトロポリア応用科学大学への短期留学における活動報告


ja: キャリア形成支援教育プログラムの開発と教育効果の評価-「チーム医療体験学習」の実践的研究を通して-

en: We prepared career advancement program "Experience learning in medical team treatment" towards the second，third and fouth year students of dental school. This program consits of prior learningconcerned with 'Team treatment and Dental profession' and experience learning in medical team treatment at Tokushima University Hospital.The purpose of this program was to rouse career conciousness as a dentalprofession. This program provided students with career image which they want to be in the future. Besides，they were motivated to study more widely to approach their own image. In this paper，we evaluated theeffects of the program"The experience learning in medical team treatment" on career advancement ofdental school students. As a result，it is suggested that this program might be fruitful as career advancement on dental students.我々は歯学部学生のキャリア形成支援のための教育プログラム「チーム医療体験学習」を開発し，歯学部の2，3，4年次の学生を対象として実施した．本プログラムは，グループワークによる事前学習とチーム医療の現場体験を2つの柱とし，学生の歯科医療職としてのキャリア意識を強化することを目的とした．プログラム終了時のアンケートから，学生には歯科専門職としての将来の姿勢や目指す方向性が具体化すると同時に幅広い知識を身につけたいといった学習に対する動機付が強化されるなど明らかな教育成果が認められた．プログラム実施前後のアンケートの分析結果から， 「チーム医療体験学習」が歯学部学生のキャリア形成支援教育の手法として有効なプログラムである可能性が示唆された．

en: Journal of University Education Research


en: Report: Chosun University School of Dentistry (in Japanese)

ja: 朝鮮大学校歯科大学訪問の報告


en: The primary therapy of oral squamous cell carcinoma by UFT and OK-432 in combination with Radiotherapy

ja: 口腔扁平上皮癌に対するUFT,OK-432, 放射線治療を併用した一次治療

en: BIOTHERAPY

ja: BIOTHERAPY