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徳島大学 > 研究クラスター群 > 研究クラスター群 (登録) > 1704002 細胞内Zn2+動態を制御する化合物の開発 ― 生物資源の活用 >
徳島大学 > 研究クラスター群 > 研究クラスター群 (選定) > 1703021 難消化性食品成分による有害物質の制御と応用 >

研究活動

専門分野

細胞生物学 (Cell Biology)
細胞計測学 (Cytometry)

研究テーマ

細胞死と化学物質の物理化学的性質の関連性, 細胞死プロセスの解析, 環境汚染物質による細胞死,細胞傷害 (細胞死 (cell death), 環境汚染物質 (Environmental pollutants), 細胞計測学 (cytometric analysis), 細胞毒性 (cytotoxicity))
レーザー蛍光化学的手法を用いる細胞膜及び細胞内動態の非侵襲的解析, 化学物質の細胞影響評価

著書・論文

著書:

1.小山 保夫 :
フローサイトメーターの脳神経細胞への応用, --- - 特に,神経細胞の細胞死の蛍光化学的評価 - ---,
九州大学出版会, 福岡, 1998年1月.
2.赤池 紀扶, 小山 保夫 :
イオンチャネルとレセプター, --- 神経細胞のK+チャネル - 中枢神経細胞に於けるA電流について - ---,
株式会社 羊土社, 東京, 1992年1月.
3.Yasuo Oyama and Norio Akaike :
Molluscan Neurobiology, --- GABA affects the glutamate Cl- response in physically-isolated and internally-perfused Aplysia neurons ---,
North-Holland, Amsterdam, Jan. 1984.
4.Katsuhide Nishi, Yasuo Oyama and Norio Akaike :
Membrane Permeability: Experiments and Models, --- Substances modifying calcium channel in Helix neuron ---,
Techsearch Inc., Adelaide, Jan. 1984.
5.Norio Akaike, Katsuhide Nishi and Yasuo Oyama :
The Mechanism of Gated Calcium Transport across Biological Membranes, --- The manganese current of Helix neuron ---,
Academic Press, New York, Jan. 1981.

学術論文(審査論文):

1.Tomomi Inoue, Maika Kinoshita, Keisuke Oyama, Kamemura Norio and Yasuo Oyama :
Captan-induced increase in the concentrations of intracellular Ca2+ and Zn2+ and its correlation with oxidative stress in rat thymic lymphocytes,
Environmental Toxicology and Pharmacology, Vol.63, 78-83, 2018.
(DOI: 10.1016/j.etap.2018.08.017)
2.Takumi Kishida, Yurie Funakoshi, Yuya Fukuyama, Sari Honda, Toshiya Masuda and Yasuo Oyama :
Conflicting actions of 4-vinylcatechol in rat lymphocytes under oxidative stress induced by hydrogen peroxide,
Drug and Chemical Toxicology, Vol.6, 1-6, 2018.
(徳島大学機関リポジトリ: 111990,   DOI: 10.1080/01480545.2018.1492604)
3.Takumi Kishida, Kenji Akiyoshi, Erdenedalai Erdenebat, Enhetomuru Anu, Shoji Imai and Yasuo Oyama :
Cellular adverse actions of dibromoacetonitrile, a by-product in water bacterial control, at sublethal levels in rat thymocytes,
Toxicology In Vitro, Vol.51, 145-149, 2018.
(徳島大学機関リポジトリ: 111989,   DOI: 10.1016/j.tiv.2018.05.011,   Elsevier: Scopus)
4.Yurie Funakoshi, Ayako Azuma, Mizuki Ishikawa, Satoru Itsuki, Yasuaki Tamura, Kaori Kanemaru, Shogo Hirai and Yasuo Oyama :
Cytometrical analysis of the adverse effects of indican, indoxyl, indigo, and indirubin on rat thymic lymphocytes,
Toxicology Research, Vol.7, 513-520, 2018.
(徳島大学機関リポジトリ: 111988,   DOI: 10.1039/C7TX00244K,   Elsevier: Scopus)
5.Mizuki Ikeda, Junji Deguchi, Shota Fukushima, Ai Qingyu, Norihiro Katayama, Hajime Miura and Yasuo Oyama :
Some adverse actions of chlorothalonil at sublethal levels in rat thymic lymphocytes: Its relation to Zn2+,
Environmental Toxicology and Pharmacology, Vol.59, 61-65, 2018.
(徳島大学機関リポジトリ: 111987,   DOI: 10.1016/j.etap.2018.03.006)
6.Kazuki Noma, Hironari Aakike, Yuki Kurauchi, Hiroshi Katsuki, Yasuo Oyama and Norio Akaike :
Effects of triphenyltin on glycinergic transmission on rat spinal neurons,
Environmental Research, Vol.163, 163-193, 2018.
(徳島大学機関リポジトリ: 111986,   DOI: 10.1016/j.envres.2018.02.005)
7.Honoka Wada, Keisuke Oyama, Risa Kamae, Toshiya Masuda, Kaori Kanemaru, Kumio Yokoigawa and Yasuo Oyama :
Zinc-dependent and independent actions of hydroxyhydroquinone on rat thymic lymphocytes,
Drug and Chemical Toxicology, Vol.9, 1-6, 2018.
(徳島大学機関リポジトリ: 111979,   DOI: 10.1080/01480545.2018.1429462)
8.Yumiko Nishimura-Danjobara, Keisuke Oyama, Kumio Yokoigawa and Yasuo Oyama :
Hyperpolarization by N-(3-oxododecanoyl)-L-homoserine-lactone, a quorum sensing molecule, in rat thymic lymphocytes,
Chemico-Biological Interactions, Vol.283, 91-96, 2018.
(徳島大学機関リポジトリ: 111985,   DOI: 10.1016/j.cbi.2018.02.008,   PubMed: 29427588)
9.Yumiko Nishimura-Danjobara, Keisuke Oyama, Kaori Kanemaru, Keiko Takahashi, Kumio Yokoigawa and Yasuo Oyama :
N-(3-oxododecanoyl)-L-homoserine-lactone, a quorum sensing molecule, affects cellular content of nonprotein thiol content in rat lymphocytes: Its relation with intracellular Zn2+,
Chemico-Biological Interactions, Vol.280, 28-32, 2018.
(徳島大学機関リポジトリ: 111976,   DOI: 10.1016/j.cbi.2017.12.013,   PubMed: 29223568)
10.Yumiko Kanemoto-Kataoka, Keisuke Oyama, Tomohiro Oyama, Hitoshi Ishibashi and Yasuo Oyama :
Ziram, a dithiocarbamate fungicide, exhibits pseudo-cytoprotective actions against oxidative stress in rat thymocytes: Possible environmental risks,
Environmental Research, Vol.160, 232-238, 2018.
(徳島大学機関リポジトリ: 111982,   DOI: 10.1016/j.envres.2017.09.027,   PubMed: 29028487,   Elsevier: Scopus)
11.Norio Kamemura, Keisuke Oyama, Kaori Kanemaru, Kumio Yokoigawa and Yasuo Oyama :
Diverse cellular actions of tert-butylhydroquinone, a food additive, on rat thymocytes,
Toxicology Research, Vol.6, 922-929, 2017.
(徳島大学機関リポジトリ: 111981,   DOI: 10.1039/C7TX00183E)
12.Keisuke Oyama, Norikazu Miyoshi and Yasuo Oyama :
Cytometric analysis on cytotoxicity of 4,4 -methylenediphenyl diisocyanate, a chemical allergen, in rat thymocytes,
Fundamental Toxicological Sciences, Vol.4, No.4, 173-178, 2017.
(徳島大学機関リポジトリ: 111202,   DOI: 10.2131/fts.4.173)
13.Yumiko Kanemoto-Kataoka, Tomohiro Oyama, Hitoshi Ishibashi and Yasuo Oyama :
Zinc is a determinant of the cytotoxicity of Ziram, a dithiocarbamate fungicide, in rat thymic lymphocytes: Possible environmental risk,
Toxicology Research, Vol.6, 499-504, 2017.
(徳島大学機関リポジトリ: 111983,   DOI: 10.1039/C7TX00052A)
14.Masahito Wakita, Kiyomitsu Shoudai, Yasuo Oyama and Norio Akaike :
4,5-Dichloro-2-octyl-4-isothiazolin-3-one (DCOIT) modifies synaptic transmission in hippocampal CA3 neurons of rats,
Chemosphere, Vol.184, 337-346, 2017.
(徳島大学機関リポジトリ: 111980,   DOI: 10.1016/j.chemosphere.2017.05.158)
15.Tsuyoshi Mitani, Ahmed Elhossany Elmarhomy Ibrahim, Luvsandorj Dulamjav, Enkhtumur Anu, Shohei Saitoh, Shiro Ishida and Yasuo Oyama :
Zinc-related actions of sublethal levels of benzalkonium chloride: Potentiation of benzalkonium cytotoxicity by zinc,
Chemico-Biological Interactions, Vol.268, 31-36, 2017.
(徳島大学機関リポジトリ: 111111,   DOI: 10.1016/j.cbi.2017.02.017,   PubMed: 28257953,   Elsevier: Scopus)
16.Risa Kamae, Shoko Nojima, Kenji Akiyoshi, Shoki Setsu, Sari Honda, Toshiya Masuda and Yasuo Oyama :
Hydroxyhydroquinone, a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes,
Food and Chemical Toxicology, Vol.102, 39-45, 2017.
(徳島大学機関リポジトリ: 111018,   DOI: 10.1016/j.fct.2017.01.025,   PubMed: 28153638)
17.Badr Ali Hoida, Takahashi Keiko, Ryushi Kawakami, Yasuo Oyama, Kumio Yokoigawa and Kaori Kanemaru :
Screening and analysis of edible seaweeds in the ability to adsorb Shiga toxin.,
European Food Research and Technology, 2017.
(徳島大学機関リポジトリ: 111019,   DOI: 10.1007/s00217-017-2915-1)
18.Hiroto Imai, Fumiya Kita, Sho Ikesugi, Masami Abe, Shizuka Sogabe, Yumiko Nishimura-Danjobara, Hajime Miura and Yasuo Oyama :
Cetylpyridinium chloride at sublethal levels increases the susceptibility of rat thymic lymphocytes to oxidative stress,
Chemosphere, Vol.170, 118-123, 2017.
(徳島大学機関リポジトリ: 111974,   DOI: 10.1016/j.chemosphere.2016.12.023,   Elsevier: Scopus)
19.Maki Takeda, Keisuke Oyama, Norio Kamemura, Kaori Kanemaru, Keizo Yuasa, Kumio Yokoigawa and Yasuo Oyama :
Change in plasma membrane potential of rat thymocytes by tert-butylhydroquinone, a food additive: Possible risk on lymphocytes,
Food and Chemical Toxicology, Vol.109, No.1, 296-301, 2017.
(徳島大学機関リポジトリ: 111984,   DOI: 10.1016/j.fct.2017.09.017,   PubMed: 28899772,   Elsevier: Scopus)
20.Kayo Nonami, Shohei Saitoh, Yumiko Nishimura-Danjobara, Shiro Ishida and Yasuo Oyama :
Chlorhexidine possesses unique cytotoxic actions in rat thymic lymphocytes: Its relation with electrochemical property of membranes,
Environmental Toxicology and Pharmacology, Vol.48, 17-21, 2016.
(徳島大学機関リポジトリ: 110890,   DOI: 10.1016/j.etap.2016.09.024,   Elsevier: Scopus)
21.Eiko Niwa, Tsuyoshi Mitani, Shohei Saitoh, Kaori Kanemaru, Shiro Ishida, Kumio Yokoigawa and Yasuo Oyama :
Zinc increases vulnerability of rat thymic lymphocytes to arachidonic acid under in vitro conditions,
Food and Chemical Toxicology, Vol.96, 177-182, 2016.
(徳島大学機関リポジトリ: 110419,   DOI: 10.1016/j.fct.2016.08.008,   PubMed: 27515868)
22.Mizuki Ishikawa, Ryosuke Muraguchi, Ayako Azuma, Shogo Nawata, Tetsuya Katsuur, Mutsumi Miya, Tohru Naito and Yasuo Oyama :
Cytotoxic actions of 2,2-dibromo-3-nitrilopropionamide, a biocide in hydraulic fracturing fluids, on rat thymocytes,
Toxicology Research, Vol.5, 1329-1334, 2016.
(徳島大学機関リポジトリ: 110172,   DOI: 10.1039/c6tx00027d,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
23.Hiromitsu Tsuzuki, Shota Inoue, Daiki Kobayashi, Gantulga Uuganbaatar, Kaori Kanemaru, Kumio Yokoigawa and Yasuo Oyama :
Methyl cinnamate increases cell vulnerability to oxidative stress induced by hydrogen peroxide in rat thymocytes,
Fundamental Toxicological Sciences, Vol.3, No.3, 121-125, 2016.
(徳島大学機関リポジトリ: 110051,   DOI: 10.2131/fts.3.121)
24.Eri Fukunaga, Shohei Saitoh, Yuya Kurumi, Yurie Ohiwa, Eri Kurozumi and Yasuo Oyama :
Cytotoxic actions of N-(2,4,6-trichlorophenyl)maleimide (IT-354), an antifouling agent, in rat thymic lymphocytes,
Fundamental Toxicological Sciences, Vol.2, No.5, 217-222, 2015.
(DOI: 10.2131/fts.2.217)
25.Eri Fukunaga, Sari Honda, Yuji Hashimoto, Yasuaki Tamura, Shiro Ishida and Yasuo Oyama :
Zn2+-dependent increase in cells with phosphatidylserine-exposed membranes after treatment with submicromolar concentrations of 2-n-octyl-4-isothiazolin-3-one in rat thymocytes,
Fundamental Toxicological Sciences, Vol.2, No.5, 209-216, 2015.
(DOI: 10.2131/fts.2.209,   CiNii: 130005109680)
26.Shohei Saitoh, Eri Fukunaga, Hana Ohtani and Yasuo Oyama :
Zn2+-dependence of the synergistic increase in rat thymocyte cell lethality caused by simultaneous application of 4,5-dichloro-2-octyl-4-isothiazolin-3-one (DCOIT) and H2O2,
Chemosphere, Vol.135, 447-452, 2015.
(DOI: 10.1016/j.chemosphere.2014.10.089,   PubMed: 25582392,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
27.Eri Fukunaga, Kana Enma, Shohei Saitoh, Yumiko Nishimura-Danjyobara, Yasuo Oyama and Norio Akaike :
Increase in intracellular Ca2+ level by phenylsulfamide fungicides, tolylfluanid and dichlofluanid, in rat thymic lymphocytes,
Environmental Toxicology and Pharmacology, Vol.40, No.1, 149-155, 2015.
(DOI: 10.1016/j.etap.2015.06.004,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
28.Yumiko Kanemoto-Kataoka, Tomohiro Oyama, Hitoshi Ishibashi and Yasuo Oyama :
Dithiocarbamate fungicides increase intracellular Zn2+ levels by increasing influx of Zn2+ in rat thymic lymphocytes,
Chemico-Biological Interactions, Vol.237, 80-86, 2015.
(DOI: 10.1016/j.cbi.2015.05.014,   PubMed: 26026913,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
29.Masahito Wakita, Yasuo Oyama, Yuko Takase and Norio Akaike :
Modulation of excitatory synaptic transmission in rat hippocampal CA3 neurons by triphenyltin, an environmental pollutant,
Chemosphere, Vol.120, 598-607, 2015.
(DOI: 10.1016/j.chemosphere.2014.09.073,   PubMed: 25462303,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
30.Eri Fukunaga, Tomohiro Oyama and Yasuo Oyama :
Elevation of intracellular Zn2+ level by 2-n-octyl-4-isothiazolin-3-one in rat thymocytes: An involvement of a temperature-sensitive Zn2+ pathway,
Toxicology Research, Vol.4, No.1, 65-70, 2015.
(DOI: 10.1039/C4TX00060A,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
31.Hana Ohtani, Eri Fukunaga, Yasuo Oyama, Shiro Ishida and Norio Akaike :
The paradoxical effect of 1,4-naphthoquinone on the process of cell death induced by hydrogen peroxide in rat thymocytes,
Fundamental Toxicological Sciences, Vol.1, No.4, 123-129, 2014.
(DOI: 10.2131/fts.1.123,   CiNii: 130005083349)
32.Eri Fukunaga, Shiro Ishida and Yasuo Oyama :
Changes in cellular thiol content and intracellular Zn2+ level by 1,4-naphthoquinone in rat thymocytes,
Chemico-Biological Interactions, Vol.222, 1-6, 2014.
(DOI: 10.1016/j.cbi.2014.08.007,   PubMed: 25168851)
33.Eri Fukunaga, Yumi Hirao, Ikuko Ogata-Ikeda, Yumiko Nishimura, Hakaru Heo and Yasuo Oyama :
Bisabololoxide A, one of the constituents in German Chamomile extract, attenuates cell death induced by calcium overload,
Phytotherapy Research, Vol.28, No.5, 685-691, 2014.
(DOI: 10.1002/ptr.5041,   PubMed: 23873581,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
34.Yukari Miura, Xiaohui Chen, Saki Yamada, Aya Sugihara, Molomjamts Enkhjargal, Yuanzhi Sun, Keiko Kuroda, Masaya Satoh and Yasuo Oyama :
Triclocarban-induced change in intracellular Ca2+ level in rat thymocytes: Cytometric analysis with Fluo-3 under Zn2+-free conditions,
Environmental Toxicology and Pharmacology, Vol.37, No.2, 563-570, 2014.
(DOI: 10.1016/j.etap.2014.01.013,   PubMed: 24562054,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
35.Tomohiro Oyama, Keisuke Oyama, Eri Fukunaga, Hitoshi Ishibashi and Yasuo Oyama :
Clioquinol, a lipophilic Zn2+ chelator, augments and attenuates the cytotoxicity of H2O2: A bell-shaped response curve of the effects of the drug,
Toxicology Research, Vol.3, No.2, 110-117, 2014.
(DOI: 10.1039/C3TX50097G,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
36.Abdul Hameed, Masaya Satoh, Yuka Furuhashi, Yasuo Oyama and Shahida Hasnain :
Induction of non protein thiols by chromium in cyanobacteria isolated from polluted areas,
African Journal of Microbiology Research, Vol.7, No.40, 4806-4811, 2013.
(DOI: 10.5897/AJMR2013.5968)
37.Yuanzhi Sun, Molomjamts Enkhjargal, Aya Sugihara, Saki Yamada, Xiaohui Chen, Yukari Miura, Eri Fukunaga, Masaya Satoh and Yasuo Oyama :
Effect of triclocarban on membrane potential of rat thymocytes: Assessment with bis-(1,3-dibutylbarbituric acid)trimethine oxonol,
Natural Science Research, Vol.27, No.4, 51-57, 2013.
(徳島大学機関リポジトリ: 105960)
38.Tsolmon Chimeddorj, Tomoko Suzuki, Kazuhiro Murakane, Miyuki Inai, Masaya Satoh and Yasuo Oyama :
Synergistic increase in cell lethality by dieldrin and H2O2 in rat thymocytes: Effect of dieldrin on the cells exposed to oxidative stress,
Chemosphere, Vol.93, No.2, 353-358, 2013.
(DOI: 10.1016/j.chemosphere.2013.04.092,   PubMed: 23726008,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
39.Eri Fukunaga, Yasuhiro Kanbara, Yumi Hirao and Yasuo Oyama :
Role of Zn2+ in restoration of nonprotein thiol content in the cells under chemical stress induced by triclocarban,
Natural Science Research, Vol.27, No.1, 1-5, 2013.
(徳島大学機関リポジトリ: 104978,   CiNii: 120005267183)
40.Yasuhiro Kanbara, Kazuhiro Murakane, Yumiko Nishimura, Masaya Satoh and Yasuo Oyama :
Nanomolar concentration of triclocarban increases the vulnerability of rat thymocytes to oxidative stress,
The Journal of Toxicological Sciences, Vol.38, No.1, 49-55, 2013.
(DOI: 10.2131/jts.38.49,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
41.Junpei Morita, Aoi Teramachi, Yosuke Sanagawa, Saramaiti Toyson, Hiroshi Yamamoto and Yasuo Oyama :
Elevation of intracellular Zn2+ level by nanomolar concentrations of triclocarban in rat thymocytes,
Toxicology Letters, Vol.215, No.3, 208-213, 2012.
(DOI: 10.1016/j.toxlet.2012.10.012,   PubMed: 23099084,   Thomson Reuters: Web of Science™)
42.Yusuke Takahashi, Kaori Kanemaru, Shoji Imai, Norikazu Miyoshi, Takuya Kawanai and Yasuo Oyama :
Yttrium decreases the intracellular Zn2+ concentration in rat thymocytes by attenuating a temperature-sensitive Zn2+ influx,
Environmental Toxicology and Pharmacology, Vol.34, No.2, 574-578, 2012.
(DOI: 10.1016/j.etap.2012.07.002,   PubMed: 22854244,   Elsevier: Scopus)
43.Tomohiro Oyama, Shiro Ishida, Yoshiro Okano, Hakaru Seo and Yasuo Oyama :
Clioquinol-induced increase and decrease in the intracellular Zn2+ level in rat thymocytes,
Life Sciences, Vol.91, No.23-24, 1216-1220, 2012.
(DOI: 10.1016/j.lfs.2012.09.014,   PubMed: 23044228,   Thomson Reuters: Web of Science™)
44.Hakaru Seo, Ikuko Ogata-Ikeda, Shiro Ishida, Yoshiro Okano and Yasuo Oyama :
A comparison of the cellular actions of polaprezinc (zinc-L-carnosine) and ZnCl2,
Life Sciences, Vol.90, No.25-26, 1015-1019, 2012.
(DOI: 10.1016/j.lfs.2012.05.017,   PubMed: 22683432)
45.Yasuhiro Kanbara, Hakaru Seo, Yumiko Nishimura and Yasuo Oyama :
Decrease in intracellular Zn2+ level by propranolol: A model experiment using rat thymocytes,
Natural Science Research, Vol.26, No.3, 11-16, 2012.
(徳島大学機関リポジトリ: 96890,   CiNii: 120004211422)
46.Tomohiro Oyama, Minoru Saito, Takayasu Yonezawa, Okano Yoshiro and Yasuo Oyama :
Nanomolar concentrations of zinc pyrithione increase cell susceptibility to oxidative stress induced by hydrogen peroxide in rat thymocytes,
Chemosphere, Vol.87, No.11, 1316-1322, 2012.
(DOI: 10.1016/j.chemosphere.2012.01.052,   PubMed: 22356860,   Thomson Reuters: Web of Science™)
47.Yumiko Nishimura and Yasuo Oyama :
Further analysis on lidocaine-induced increase in intracellular Zn2+ concentration: Cytometric model study using FluoZin-3, 5-chloromethylfluorescein, and rat thymocytes,
Natural Science Research, Vol.26, No.2, 7-10, 2012.
(徳島大学機関リポジトリ: 96861,   CiNii: 120004123078)
48.Ikumi Tamura, Yasuhiro Kanbara, Minoru Saito, Kanna Horimono, Masaya Satoh, Hiroshi Yamamoto and Yasuo Oyama :
Triclosan, an antibacterial agent, increases intracellular Zn2+ concentration in rat thymocytes: Its relation to oxidative stress,
Chemosphere, Vol.86, No.1, 70-75, 2012.
(DOI: 10.1016/j.chemosphere.2011.09.009,   PubMed: 22000841,   Thomson Reuters: Web of Science™)
49.Ikumi Tamura, Minoru Saito, Yumiko Nishimura, Masaya Satoh, Hiroshi Yamamoto and Yasuo Oyama :
Elevation of intracellular Ca2+ level by triclosan in rat thymic lymphocytes: Increase in membrane Ca2+ permeability and induction of intracellular Ca2+ release,
Journal of Health Science, Vol.57, No.6, 540-546, 2011.
(DOI: 10.1248/jhs.57.540,   CiNii: 40019073438,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
50.Takuya Kawanai, Masahiro Fujinaga, Kazuki Koizumi, Isao Kurotani, Erika Hashimoto, Masaya Satoh, Shoji Imai, Norikazu Miyoshi and Yasuo Oyama :
Some characteristics of membrane Cd2+ transport in rat thymocytes: An analysis using Fluo-3,
Biometals, Vol.24, No.5, 903-914, 2011.
(DOI: 10.1007/s10534-011-9444-3,   PubMed: 21455662,   Elsevier: Scopus)
51.Kazuki Koizumi, Kawanai Takuya, Erika Hashimoto, Yasuhiro Kanbara, Toshiya Masuda, Kaori Kanemaru, Yoshiro Okano and Yasuo Oyama :
Cytometric analysis on cytotoxicity of curcumin on rat thymocytes: Proapoptotic and antiapoptotic actions of curcumin,
Toxicology In Vitro, Vol.25, No.4, 985-990, 2011.
(DOI: 10.1016/j.tiv.2011.03.010,   PubMed: 21419841,   Thomson Reuters: Web of Science™)
52.Ikuko Ogata, Hakaru Seo, Takuya Kawanai, Erika Hashimoto and Yasuo Oyama :
Cytotoxic actions of bisabololoxide A (a constituent of German chamomile extract), 5-fluorouracil, and their combination on human leukemia K562 cells,
Phytomedicine, Vol.18, No.5, 362-365, 2011.
(DOI: 10.1016/j.phymed.2010.08.007,   PubMed: 20863677)
53.Yoshimi Shingai, Aya Fujimoto, Asuka Nakajima, Minoru Saito, Kaori Kanemaru, Toshiya Masuda and Yasuo Oyama :
Cytotoxic characteristics of two isomeric dimers produced by oxidation of sesamol, an antioxidant in sesame oil,
Journal of Health Science, Vol.57, No.5, 425-431, 2011.
(DOI: 10.1248/jhs.57.425,   CiNii: 130001151384,   Thomson Reuters: Web of Science™)
54.Yosuke Endo, Zhehao Han, Jun Kurochi, Masahiro Sakata, Akinori Maetaka, Takayasu Yonezawa, Kazuki Koizumi and Yasuo Oyama :
Zinc-pyrithione exerts diverse actions on human leukemia K562 cells: A preliminary study on hormetic action,
Natural Science Research, Vol.25, No.3, 15-19, 2011.
(徳島大学機関リポジトリ: 76979,   CiNii: 110008761219)
55.Akio Kinazaki, Hongqin Chen, Kazuki Koizumi, Takuya Kawanai, Tomohiro Oyama, Masaya Satoh, Shiro Ishida, Yoshiro Okano and Yasuo Oyama :
Putative role of intracellular Zn2+ release during oxidative stress: A trigger to restore cellular thiol content that is decreased by oxidative stress,
The Journal of Physiological Sciences, Vol.61, No.5, 403-409, 2011.
(DOI: 10.1007/s12576-011-0160-0,   PubMed: 21744294,   Thomson Reuters: Web of Science™)
56.Kaori Kimura, Yumiko Nishimura, Keisuke Oyama, Takuya Kawanai, Erika Hashimoto and Yasuo Oyama :
Tetracaine decreases intracellular Zn2+ concentration by inhibiting Zn2+ influx in rat thymocytes,
Natural Science Research, Vol.25, No.2, 7-13, 2011.
(徳島大学機関リポジトリ: 74628,   CiNii: 110008761213)
57.Soya Harada, Chiharu Kubota, Natsuho Kitano, Takuya Kawanai, Kazuki Koizumi, Yasuo Oyama, Akio Kinazaki, Shiro Ishida and Yoshiro Okano :
NOR-3, a donor of nitric oxide, increases intracellular Zn2+ concentration and decreases cellular thiol content: A model experiment using rat thymocytes, FluoZin-3, and 5-chloromethylfluorescein,
Natural Science Research, Vol.25, No.1, 1-6, 2011.
(徳島大学機関リポジトリ: 74530,   CiNii: 110008761209)
58.Aya Fujimoto, Yoshimi Shingai, Toshihisa Oyama, Takuya Kawanai, Erika Hashimoto, Kazuki Koizumi, Kaori Kimura, Toshiya Masuda and Yasuo Oyama :
Apoptosis-inducing action of two products from oxidation of sesamol, an antioxidative constituent of sesame oil: a possible cytotoxicity of oxidized antioxidant,
Toxicology In Vitro, Vol.24, No.6, 1720-1726, 2010.
(DOI: 10.1016/j.tiv.2010.05.013,   PubMed: 20510349,   Thomson Reuters: Web of Science™)
59.Toshiya Masuda, Yoshimi Shingai, Aya Fujimoto, Mitsuhiro Nakamura, Yasuo Oyama, Tomomi Maekawa and Yoshiaki Sone :
Identification of cytotoxic dimers in oxidation product from sesamol, a potent antioxidant of sesame oil,
Journal of Agricultural and Food Chemistry, Vol.58, No.20, 10880-10885, 2010.
(DOI: 10.1021/jf103015j,   PubMed: 20925385)
60.Hiroko Matsui, Tomohiro Oyama, Yoshiro Okano, Erika Hashimoto, Takuya Kawanai and Yasuo Oyama :
Low micromolar zinc exerts cytotoxic action under H2O2-induced oxidative stress: Excessive increase in intracellular Zn2+ concentration,
Toxicology, Vol.276, No.1, 27-32, 2010.
(DOI: 10.1016/j.tox.2010.06.011,   PubMed: 20603178,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
61.Takuya Kawanai, Soya Harada, Chiharu Kubota, Erika Hashimoto and Yasuo Oyama :
ZnCl2 and vitamin C, known as antioxidants, differently potentiate the cytotoxicity of H2O2 in rat thymocytes: Cytometric analysis using forward and side scatters,
Natural Science Research, Vol.24, No.3, 12-19, 2010.
(徳島大学機関リポジトリ: 69789,   CiNii: 120002833594)
62.Erika Hashimoto, Kaori Kimura, Takuya Kawanai, Yumiko Nishimura and Yasuo Oyama :
Nitroprusside increases intracellular Zn2+ concentration without affecting cellular thiol content: A model experiment using rat thymocytes and FluoZin-3,
Natural Science Research, Vol.24, No.2, 6-11, 2010.
(徳島大学機関リポジトリ: 66467,   CiNii: 120002833593)
63.Tomohiro Oyama, Keisuke Oyama, Toshihisa Oyama, Shiro Ishida, Yoshiro Okano and Yasuo Oyama :
Zinc at clinically-relevant concentrations potentiates the cytotoxicity of polysorbate 80, a nonionic surfactant,
Toxicology In Vitro, Vol.24, No.3, 737-744, 2010.
(DOI: 10.1016/j.tiv.2010.01.004,   PubMed: 20079827,   Thomson Reuters: Web of Science™)
64.Yumiko Nishimura and Yasuo Oyama :
Cytotoxic actions of lidocaine at sublethal concentrations: A model in vitro experiment using rat thymocytes,
Natural Science Research, Vol.24, No.1, 1-5, 2010.
(徳島大学機関リポジトリ: 65344,   CiNii: 110008703785)
65.Ikuko Ogata, Takuya Kawanai, Erika Hashimoto, Yumiko Nishimura, Hakaru Seo and Yasuo Oyama :
Bisabololoxide A, one of main constituents in chamomile extract, induces apoptosis in rat thymocytes,
Archives of Toxicology, Vol.84, No.1, 45-52, 2010.
(DOI: 10.1007/s00204-009-0472-5,   PubMed: 19834689)
66.Takuya Kawanai, Masaya Satoh, Koji Murao and Yasuo Oyama :
Methylmercury elicits intracellular Zn2+ release in rat thymocytes: Its relation to methylmercury-induced decrease in cellular thiol content,
Toxicology Letters, Vol.191, No.2-3, 231-235, 2009.
(DOI: 10.1016/j.toxlet.2009.09.003,   PubMed: 19748556)
67.Toshihisa Oyama, Keisuke Oyama, Takuya Kawanai, Tomohiro Oyama, Erika Hashimoto, Masaya Satoh and Yasuo Oyama :
Tri-n-butyltin increases intracellular Zn2+ concentration by decreasing cellular thiol content in rat thymocytes,
Toxicology, Vol.262, No.3, 245-249, 2009.
(DOI: 10.1016/j.tox.2009.06.016,   PubMed: 19559746,   Thomson Reuters: Web of Science™)
68.Hiroko Matsui, Yoko Sakanashi, Yumiko Nishimura, Takuya Kawanai, Yasuo Oyama, Shiro Ishida and Yoshiro Okano :
Effects of Zn2+ chelators, DTPA and TPEN, and ZnCl2 on the cells treated with hydrogen peroxide: a flow-cytometric study using rat thymocytes,
Natural Science Research, Vol.23, No.2, 13-19, 2009.
(徳島大学機関リポジトリ: 63727,   CiNii: 120002693581)
69.Erika Hashimoto, Toshihisa Oyama, Keisuke Oyama, Yumiko Nishimura, Tomohiro Oyama, Toshiko Ueha-Ishibashi, Yoshiro Okano and Yasuo Oyama :
Increase in intracellular Zn2+ concentration by thimerosal in rat thymocytes: Intracellular Zn2+ release induced by oxidative stress,
Toxicology In Vitro, Vol.23, No.6, 1092-1099, 2009.
(DOI: 10.1016/j.tiv.2009.05.020,   PubMed: 19497362,   Thomson Reuters: Web of Science™)
70.Toshiya Masuda, Aya Fujimoto, Yasuo Oyama, Tomomi Maekawa and Yoshiaki Sone :
Structures of cytotoxic products from Fe-catalyzed oxidation of sesamol in ethanol,
Tetrahedron Letters, Vol.50, No.27, 3905-3908, 2009.
(DOI: 10.1016/j.tetlet.2009.04.063)
71.Aya Fujimoto, Yoko Sakanashi, Hiroko Matusi, Toshihisa Oyama, Yumiko Nishimura, Toshiya Masuda and Yasuo Oyama :
Cytometric analysis of cytotoxicity of polyphenols and related phenolics to rat thymocytes: Potent cytotoxicity of resveratrol to normal cells,
Basic & Clinical Pharmacology & Toxicology, Vol.104, No.6, 455-462, 2009.
(DOI: 10.1111/j.1742-7843.2009.00386.x,   PubMed: 19389048,   Thomson Reuters: Web of Science™)
72.Akio Kinazaki, Yoko Sakanashi, Tomohiro Oyama, Haruka Shibagaki, Kohei Yamashita, Erika Hashimoto, Yumiko Nishimura, Shiro Ishida, Yoshiro Okano and Yasuo Oyama :
Micromolar Zn2+ potentiates the cytotoxic action of submicromolar econazole in rat thymocytes: Possible disturbance of intracellular Ca2+ and Zn2+ homeostasis,
Toxicology In Vitro, Vol.23, No.4, 610-616, 2009.
(DOI: 10.1016/j.tiv.2009.02.001,   PubMed: 19490836,   Thomson Reuters: Web of Science™)
73.Jun Akiyama, Hiroshi Ogasa, Yoshiko Hirata, Kohei Yamashita, Haruka Shibagaki, Fumika Tanaka, Yoko Sakanashi and Yasuo Oyama :
Effect of econazole on membrane calcium transport in rat thymocytes,
Natural Science Research, Vol.23, No.1, 1-6, 2009.
(徳島大学機関リポジトリ: 63019,   CiNii: 110008699543)
74.Yoko Sakanashi, Tomohiro Oyama, Yuki Matsuo, Toshihisa Oyama, Yumiko Nishimura, Shiro Ishida, Shoji Imai, Yoshiro Okano and Yasuo Oyama :
Zn2+, derived from cell preparation, partly attenuates Ca2+-dependent cell death induced by A23187, calcium ionophore, in rat thymocytes,
Toxicology In Vitro, Vol.23, No.2, 338-345, 2009.
(DOI: 10.1016/j.tiv.2008.12.006,   PubMed: 19124067,   Thomson Reuters: Web of Science™)
75.Hiroko Matsui, Yoko Sakanashi, Tomohiro Oyama, Yasuo Oyama, Shin-ichi Yokota, Shiro Ishida, Yoshiro Okano, Toshihisa Oyama and Yumiko Nishimura :
Imidazole antifungals, but not triazole antifungals, increase membrane Zn2+ permeability in rat thymocytes: Possible contribution to their cytotoxicity,
Toxicology, Vol.248, No.2-3, 142-150, 2008.
(DOI: 10.1016/j.tox.2008.03.022,   PubMed: 18468760,   Thomson Reuters: Web of Science™)
76.Yoko Sakanashi, Midori Morimoto, Yumiko Nishimura, Hiroko Matsui, Kaori Kanemaru, Toshiya Masuda and Yasuo Oyama :
Cytometric analysis of the cytotoxic action of adenosine 5'-monophosphate on rat thymocytes,
Journal of Health Science, Vol.54, No.6, 692-696, 2008.
(DOI: 10.1248/jhs.54.692,   CiNii: 110007005225)
77.Yumiko Nishimura, Toshihisa Oyama, Yoko Sakanashi, Tomohiro Oyama, Hiroko Matsui, Yoshiro Okano and Yasuo Oyama :
Some characteristics of quercetin-induced cytotoxicity on rat thymocytes under in vitro condition,
Toxicology In Vitro, Vol.22, No.4, 1002-1007, 2008.
(DOI: 10.1016/j.tiv.2008.02.006,   PubMed: 18356015,   Thomson Reuters: Web of Science™)
78.Yoko Sakanashi, Keisuke Oyama, Hiroko Matusi, Toshihisa Oyama, Tomohiro Oyama, Yumiko Nishimura, Hitomi Sakai and Yasuo Oyama :
Possible use of quercetin, an antioxidant, for protection of cells suffering from overload of intracellular Ca2+: A model experiment,
Life Sciences, Vol.83, No.5-6, 164-169, 2008.
(DOI: 10.1016/j.lfs.2008.05.009,   PubMed: 18586279)
79.Tomohiro Oyama, Toshihisa Oyama, Keisuke Oyama, Yoko Sakanashi, Midori Morimoto, Hiroko Matsui and Yasuo Oyama :
Clotrimazole, an antifungal drug possessing diverse actions, increases membrane permeation of cadmium in rat thymocytes,
Toxicology In Vitro, Vol.21, No.8, 1505-1512, 2007.
(DOI: 10.1016/j.tiv.2007.06.016,   PubMed: 17703912)
80.Yasuo Oyama, Hiroko Matsui, Midori Morimoto, Yoko Sakanashi, Yumiko Nishimura, Shiro Ishida and Yoshiro Okano :
Synergic cytotoxic action induced by simultaneous application of zinc and clotrimazole in rat thymocytes,
Toxicology Letters, Vol.171, No.3, 138-145, 2007.
(DOI: 10.1016/j.toxlet.2007.05.003,   PubMed: 17583447)
81.Tomohiro Oyama, Toshihisa Oyama, Keisuke Oyama, Hiroko Matsui, Kanna Horimoto, Yumiko Nishimura and Yasuo Oyama :
Clotrimazole, an antifungal drug possessing diverse actions, increases the vulnerability to cadmium in lymphocytes dissociated from rat thymus,
Toxicology, Vol.228, No.2-3, 269-279, 2006.
(DOI: 10.1016/j.tox.2006.09.007,   PubMed: 17055140)
82.Kanna Horimoto, Yumiko Nishimura, Tomohiro Oyama, Kyoko Onoda, Hiroko Matsui, Toshihisa Oyama, Kaori Kanemaru, Toshiya Masuda and Yasuo Oyama :
Reciprocal effects of glucose on the process of cell death induced by calcium ionophore or H2O2 in rat lymphocytes,
Toxicology, Vol.225, No.2-3, 97-108, 2006.
(DOI: 10.1016/j.tox.2006.05.004,   PubMed: 16784802)
83.Jun-ya Yamaguchi, Aimi Kanada, Kanna Horimoto, Tomohiro Oyama, Ken-ichi Chikutei, Yumiko Nishimura, Hiroshi Yamamoto, Shiro Ishida, Yasuo Oyama and Yoshiro Okano :
Modification of vulnerability to dodecylbenzenesulfonate, an anionic surfactant, by calcium in rat thymocytes,
Environmental Toxicology and Pharmacology, Vol.22, No.2, 234-239, 2006.
(DOI: 10.1016/j.etap.2006.03.011,   PubMed: 21783715)
84.Aimi Kanada, Jun-ya Yamaguchi, Yumiko Nishimura, Tomohiro Oyama, Masaya Satoh, Norihiro Katayama, Ken-ichi Chikutei, Yoshiro Okano and Yasuo Oyama :
Tri-n-butyltin-induced blockade of store-operated calcium influx in rat thymocytes,
Environmental Toxicology and Pharmacology, Vol.22, No.2, 213-218, 2006.
(DOI: 10.1016/j.etap.2006.03.007,   PubMed: 21783712)
85.Ken-ichi Chikutei, Tomohiro Oyama, Shiro Ishida, Yoshiro Okano, Masako Kobayashi, Hiroko Matsui, Kanna Horimoto, Yumiko Nishimura, Shin-ya Ueno and Yasuo Oyama :
Propofol, an anesthetic possessing neuroprotective action against oxidative stress, promotes the process of cell death induced by H2O2 in rat thymocytes,
European Journal of Pharmacology, Vol.540, No.1-3, 18-23, 2006.
(DOI: 10.1016/j.ejphar.2006.04.037,   PubMed: 16730701)
86.Yumiko Nishimura, Jun-ya Yamaguchi, Aimi Kanada, Kanna Horimoto, Kaori Kanemaru, Masaya Satoh and Yasuo Oyama :
Increase in intracellular Cd2+ concentration of rat cerebellar granule neurons incubated with cadmium chloride: Cadmium cytotoxicity under external Ca2+-free condition,
Toxicology In Vitro, Vol.20, No.2, 211-216, 2006.
(DOI: 10.1016/j.tiv.2005.06.006,   PubMed: 16061347,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
87.Yumiko Nishimura, Aimi Kanada, Jun-ya Yamaguchi, Kanna Horimoto, Masako Kobayashi, Tomoko Tatsuishi, Kaori Kanemaru, Shin-ya Ueno and Yasuo Oyama :
Cytometric analysis of lidocaine-induced cytotoxicity: a model experiment using rat thymocytes,
Toxicology, Vol.218, No.1, 48-57, 2006.
(DOI: 10.1016/j.tox.2005.09.016,   PubMed: 16263203,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
88.Jun-ya Yamaguchi, Yumiko Nishimura, Aimi Kanada, Masako Kobayashi, Kyoko Mishima, Tomoko Tatsuishi, Kyoko Iwase and Yasuo Oyama :
Cremophor EL, a non-ionic surfactant, promotes Ca2+-dependent process of cell death in rat thymocytes,
Toxicology, Vol.211, No.3, 179-186, 2005.
(DOI: 10.1016/j.tox.2004.10.019,   PubMed: 15925021)
89.Aimi Kanada, Yumiko Nishimura, Jun-ya Yamaguchi, Masako Kobayashi, Kyoko Mishima, Kanna Horimoto, Kaori Kanemaru and Yasuo Oyama :
Extract of Ginkgo biloba leaves attenuates kainate-induced increase in intracellular Ca2+ concentration of rat cerebellar granule neurons,
Biological & Pharmaceutical Bulletin, Vol.28, No.5, 934-936, 2005.
(DOI: 10.1248/bpb.28.934,   PubMed: 15863911)
90.Tomoko Tatsuishi, Yasuo Oyama, Kyoko Iwase, Jun-ya Yamaguchi, Masako Kobayashi, Yumiko Nishimura, Aimi Kanada and Seigo Hirama :
Polysorbate 80 increases the susceptibility to oxidative stress in rat thymocytes,
Toxicology, Vol.207, No.1, 7-14, 2005.
(DOI: 10.1016/j.tox.2004.07.020,   PubMed: 15590117)
91.Toshiko Ueha-Ishibashi, Yasuo Oyama, Hiromi Nakao, Chisato Umebayashi, Yasutaka Nishizaki, Seigo Hirama, Yoshiro Sakai, Shiro Ishida and Yoshiro Okano :
Flow-cytometric analysis on cytotoxic effect of thimerosal, a preservative in vaccines, on lymphocytes dissociated from rat thymic glands,
Toxicology In Vitro, Vol.19, No.2, 191-198, 2005.
(DOI: 10.1016/j.tiv.2004.07.004,   PubMed: 15649632,   Thomson Reuters: Web of Science™)
92.Kyoko Iwase, Yasuo Oyama, Tomoko Tatsuishi, Jun-ya Yamaguchi, Yumiko Nishimura, Aimi Kanada, Masako Kobayashi, Yuko Maemura, Shiro Ishida and Yoshiro Okano :
Cremophor EL augments the cytotoxicity of hydrogen peroxide in lymphocytes dissociated from rat thymus glands,
Toxicology Letters, Vol.154, No.1-2, 143-148, 2004.
(DOI: 10.1016/j.toxlet.2004.08.003,   PubMed: 15475188,   Thomson Reuters: Web of Science™)
93.Kyoko Iwase, Tomoko Tatsuishi, Yumiko Nishimura, Jun-ya Yamaguchi, Yasuo Oyama, Norikazu Miyoshi and Makoto Wada :
Cytometric analysis on adverse action of diphenyl ditellurde on rat thymocytes: Cell shrinkage as cytotoxic parameter,
Environmental Toxicology, Vol.19, No.6, 614-619, 2004.
(DOI: 10.1002/tox.20070,   PubMed: 15526268,   Thomson Reuters: Web of Science™)
94.Hiromi Nakao, Kaori Senokuchi, Chisato Umebayashi, Kaori Kanemaru, Toshiya Masuda, Yasuo Oyama and Shigetomo Yonemori :
Cytotoxic activity of maytanprine isolated from Maytenus diversifolia in human leukemia K562 cells,
Biological & Pharmaceutical Bulletin, Vol.27, No.8, 1236-1240, 2004.
(DOI: 10.1248/bpb.27.1236,   PubMed: 15305028)
95.Seigo Hirama, Tomoko Tatsuishi, Kyoko Iwase, Hiromi Nakao, Chisato Umebayashi, Yasutaka Nishizaki, Masako Kobayashi, Shiro Ishida, Yoshiro Okano and Yasuo Oyama :
Flow cytometric analysis on adverse effects of polysorbate 80 in rat thymocytes,
Toxicology, Vol.199, No.2-3, 137-143, 2004.
(DOI: 10.1016/j.tox.2004.02.017,   PubMed: 15147788,   Thomson Reuters: Web of Science™)
96.Toshiko Ueha-Ishibashi, Tomoko Tatsuishi, Kyoko Iwase, Hiromi Nakao, Chisato Umebayashi, Yasutaka Nishizaki, Yumiko Nishimura, Yasuo Oyama, Seigo Hirama and Yoshiro Okano :
Property of thimerosal-induced decrease in cellular content of glutathione in rat thymocytes: A flow cytometric study with 5-chloromethylfluorescein diacetate,
Toxicology In Vitro, Vol.18, No.5, 563-569, 2004.
(DOI: 10.1016/j.tiv.2004.01.002,   PubMed: 15251173,   Thomson Reuters: Web of Science™)
97.Toshiko Ueha-Ishibashi, Yasuo Oyama, Hiromi Nakao, Chisato Umebayashi, Yasutaka Nishizaki, Tomoko Tatsuishi, Kyoko Iwase, Koji Murao and Hakaru Seo :
Effect of thimerosal, a preservative in vaccines, on intracellular Ca2+ concentration of rat cerebellar neurons,
Toxicology, Vol.195, No.1, 77-84, 2004.
(DOI: 10.1016/j.tox.2003.09.002,   PubMed: 14698570,   Thomson Reuters: Web of Science™)
98.Tomoko Tatsuishi, Kyoko Iwase, Yumiko Nishimura, Hiromi Nakao, Chisato Umebayashi, Toshiko Ueha-Ishibashi, Yasuo Oyama and Alexander Boldyrev :
H2O2-induced death of rat thymocytes is delayed by thimerosal, a preservative in vaccines,
Biologicheskie Membrany, Vol.21, No.4, 306-309, 2004.
(Thomson Reuters: Web of Science™,   Elsevier: Scopus)
99.Chisato Umebayashi, Yasuo Oyama, Lumi Chikahisa-Muramatsu, Hiromi Nakao, Yasutaka Nishizaki, Mami Nakata, Fumio Soeda and Kazuo Takahama :
Tri-n-butyltin-induced cytotoxicity on rat thymocytes in presence and absence of serum,
Toxicology In Vitro, Vol.18, No.1, 55-61, 2004.
(DOI: 10.1016/j.tiv.2003.08.003,   PubMed: 14630062,   Thomson Reuters: Web of Science™)
100.Toshiya Masuda, Yasuo Oyama, Natsuko Ymamamoto, Chisato Umebayashi, Hiromi Nakao, Yukiko Toi, Yoshio Takeda, Katsuo Nakamoto, Hideki Kuninaga, Yukari NIshizato and Akira Nonaka :
Cytotoxic Screening of Medicinal and Edible Plants in Okinawa, Japan, and Identification of the Main Toxic Constituent of Rhodea japonica (Omoto),
Bioscience, Biotechnology, and Biochemistry, Vol.67, No.6, 1401-1404, 2003.
(DOI: 10.1271/bbb.67.1401,   PubMed: 12843672,   Thomson Reuters: Web of Science™)
101.Chisato Umebayashi, Natsuko Yamamoto, Hiromi Nakao, Yukiko Toi, Lumi Chikahisa-Muramatsu, Kaori Kanemaru, Toshiya Masuda and Yasuo Oyama :
Flow cytometric estimation of cytotoxic activity of rhodexin A isolated from Rhodea japonica in human leukemia K562 cells,
Biological & Pharmaceutical Bulletin, Vol.26, No.5, 627-630, 2003.
(DOI: 10.1248/bpb.26.627,   PubMed: 12736502,   Thomson Reuters: Web of Science™)
102.Hiromi Nakao, Chisato Umebayashi, Katuhiko Noda, Yoshiro Okano and Yasuo Oyama :
Formaldehyde-induced shrinkage of rat thymocytes,
Journal of Pharmacological Sciences, Vol.91, No.1, 83-86, 2003.
(DOI: 10.1254/jphs.91.83,   CiNii: 130000073733,   Thomson Reuters: Web of Science™)
103.Yasutaka Nishizaki, Hiromi Nakao, Chisato Umebayashi, Kyoko Iwase, Tomoko Tatsuishi, Masaya Satoh and Yasuo Oyama :
Increase in number of annexin V-positive living cells of rat thymocytes by intracellular Pb2+,
Environmental Toxicology and Pharmacology, Vol.15, No.1, 45-51, 2003.
(DOI: 10.1016/j.etap.2003.08.007,   PubMed: 21782679,   Thomson Reuters: Web of Science™)
104.Yasutaka Nishizaki, Yasuo Oyama, Yoshiro Sakai, Seigo Hirama, Kazuyoshi Tomita, Hiromi Nakao, Chisato Umebayashi, Shiro Ishida, Yoshiro Okano and David Carpenter :
PbCl2-induced hyperpolarization of rat thymocytes: involvement of charybdotoxin-sensitive K+ channels,
Environmental Toxicology, Vol.18, No.5, 321-326, 2003.
(DOI: 10.1002/tox.10132,   PubMed: 14502585,   Thomson Reuters: Web of Science™)
105.Yasuo Oyama, Tomohiro Arata, Lumi Chikahisa, Chisato Umebayashi, Ken Tabaru, Kei Sakai and Hiromi Hayashi :
Effects of A23187 and CaCl2 on tri-n-butyltin-induced cell death in rat thymocytes,
Environmental Toxicology and Pharmacology, Vol.13, No.1, 29-36, 2003.
(DOI: 10.1016/S1382-6689(02)00127-8,   PubMed: 21782646,   Thomson Reuters: Web of Science™)
106.Toshiya Masuda, Yasuo Oyama, Tomohiro Arata, Yuzuru Inaba and Yoshio Takeda :
Cytotoxic Activity of Quinone Derivatives of Phenolic Diterpenes from Sage,
ITE Letters, Vol.3, No.1, 39-42, 2002.
107.Hiromi Hayashi, Hitomi Sakai, Wakako Minakuchi-Fijiwara, Miki Takayama, Michiko Nakamura-Murata, Yoshiko Kamo, Kanako Funakoshi, Keisuke Fukumoto, Kaori Kanemaru, Hideyuki Nakagawa, Yasuo Oyama, Nobuyuki Shinohara and Yoshihiro Ito :
Cytokinesis arrest and nuclear fission in low density populations of Trichomonad Protozoan,
Zoological Science, Vol.19, No.10, 1089-1094, 2002.
(DOI: 10.2108/zsj.19.1089,   PubMed: 12426470,   CiNii: 110003372708,   Thomson Reuters: Web of Science™)
108.Tomohiro Arata, Yasuo Oyama, Masaya Satoh, Hiromi Hayashi and Yoshiro Okano :
Cytotoxic effects of triphenylbismuth on rat thymocytes: Comparison with bismuth chloride and triphenyltin chloride,
Environmental Toxicology, Vol.17, No.5, 472-477, 2002.
(DOI: 10.1002/tox.10081,   PubMed: 12242678,   Thomson Reuters: Web of Science™)
109.Masaya Satoh, Yoshinobu Hirachi, Ai Yoshioka, Maki Kobayashi and Yasuo Oyama :
Determination of cellular levels of nonprotein thiols and their correlations with susceptibility to mercury in phytoplankton,
Journal of Phycology, Vol.38, No.5, 983-990, 2002.
(DOI: 10.1046/j.1529-8817.2002.t01-1-01223.x,   Thomson Reuters: Web of Science™)
110.増田 俊哉, 小山 保夫, 稲葉 譲, 戸井 由紀子, 荒田 智裕, 武田 美雄, 仲本 勝男, 國永 秀樹, 西里 さおり, 野中 亮 :
沖縄産食薬用植物エタノール抽出物の抗酸化関連活性,
日本食品科学工学会誌, Vol.49, No.10, 652-661, 2002年.
(DOI: 10.3136/nskkk.49.652,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
111.Yasuo Oyama, Hitomi Sakai, Tomohiro Arata, Yoshiro Okano, Norihiko Akaike, Kei Sakai and Katuhiko Noda :
Cytotoxic effects of methanol, formaldehyde, and formate on dissociate rat thymocytes: a possibility of aspartame toxicity,
Cell Biology and Toxicology, Vol.18, No.1, 43-50, 2002.
(DOI: 10.1023/A:1014419229301,   PubMed: 11991085)
112.Yasuo Oyama, Tomohiro Arata, Lumi Chikahisa, Fumio Soeda and Kazuo Takahama :
Estimation of increased concentration of intracellular Cd2+ by fluo-3 in rat thymocytes exposed to CdCl2,
Environmental Toxicology and Pharmacology, Vol.11, No.2, 111-118, 2002.
(DOI: 10.1016/S1382-6689(01)00112-0,   PubMed: 21782592)
113.Yumiko Kanemoto, Hitoshi Ishibashi, Shin-ichiro Matsuo, Yasuo Oyama and Norio Akaike :
Modification of NMDA responses by tri-n-butyltin in rat brain neurons,
British Journal of Pharmacology, Vol.136, 35-46, 2002.
114.Toshiya Masuda, Yasuo Oyama, Shigetomo Yonemori, Yoshio Takeda, Yuko Yamanazaki, Shinichi Mizuguchi, Mami Nakata and Tomochika Tanaka :
Flow Cytometric Estimation on Cytotoxic Activity of Leaf Extracts from Seashore Plants in Subtropical Japan: Isolation, Quantification and Cytotoxic Action of (-)-Deoxypodpphyllotoxin,
Phytotherapy Research, Vol.16, No.4, 353-358, 2002.
(DOI: 10.1002/ptr.902,   PubMed: 12112292,   Thomson Reuters: Web of Science™)
115.Kiyonori Kishimoto, Shin-ichiro Matsuo, Yumiko Kanemoto, Hitoshi Ishibashi, Yasuo Oyama and Norio Akaike :
Nanomolar concentrations of tri-n-butyltin facilitate gamma-aminobutylic acidergic synaptic transmission in rat hypothalamic neuronss,
The Journal of Pharmacology and Experimental Therapeutics, Vol.299, No.1, 171-177, 2001.
(PubMed: 11561077,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
116.Toshiya Masuda, Kumiko Iritani, Shigetomo Yonemori, Yasuo Oyama and Yoshio Takeda :
Isolation and Antioxidant Activity of the Galloyl Flavonol Glycosides from a Seashore Plant, Pemphis acidula,
Bioscience, Biotechnology, and Biochemistry, Vol.65, No.6, 1302-1309, 2001.
(DOI: 10.1271/bbb.65.1302,   PubMed: 11471728,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
117.Kei Sakai, Yasuo Oyama, Yoshihito Okada, Norihiko Akaike, Mami Nakata and Lumi Chikahisa :
Tri-n-butyltin delays the cell death induced by hydrogen peroxide in rat thymocytes,
Environmental Toxicology and Pharmacology, Vol.10, 95-101, 2001.
(DOI: 10.1016/S1382-6689(01)00074-6,   PubMed: 21782563,   Elsevier: Scopus)
118.Yoshihiko Okada, Yasuo Oyama, Lumi Chikahisa, Kaori Kanemaru, Hitomi Sakai, Katuhiko Noda and Masaya Satoh :
Tri-n-butyltin-induced decrease in cellular level of glutathione in rat thymocytes: a flow cytometric study using 5-chloromethylfluorescein diacetate,
Toxicology Letters, Vol.117, 123-128, 2000.
119.Yasuo Oyama, Yuko Yamazaki, Yoshihiko Okada, Kazuo Takahama, Masaya Satoh and Hiromi Hayashi :
Toxicity of methylmercury conjugated with L-cysteine on rat thymocytes in comparison with that of methylmercury,
Environmental Toxicology and Pharmacology, Vol.9, No.1, 49-55, 2000.
(DOI: 10.1016/S1382-6689(00)00062-4,   PubMed: 11137468,   Thomson Reuters: Web of Science™,   Elsevier: Scopus)
120.Mami Nakata, Yasuo Oyama, Lumi Chikahisa, Yuko Yamazaki and Masaya Satoh :
Flow cytometric analysis on tri-n-butyltin-induced increase in annexin V binding to membranes of rat thymocytes,
Environmental Toxicology and Pharmacology, Vol.7, 267-273, 1999.
121.Masaya Satoh, Emi Karaki, Mamiko Kakehashi, Eisuke Okazaki, Toshio Gotoh and Yasuo Oyama :
Heavy-metal induced changes in cellular nonproteinaceous thiol levels and heavy metal-binding peptides in Tetraselmis tetrathele (Prasinophyceae),
Journal of Phycology, Vol.35, 989-994, 1999.
122.Yasuo Oyama, Sachi Noguchi, Mami Nakata, Yoshihiko Okada, Yuko Yamazaki, Megumi Funai, Lumi Chikahisa and Kaori Kanemaru :
Exposure of rat thymocytes to hydrogen peroxide increases annexin-V binding to membranes: inhibitory action of deferoxamine and quercetin,
European Journal of Pharmacology, Vol.384, 47-52, 1999.
123.Toshiya Masuda, Shigetomo Yonemori, Yasuo Oyama, Yoshio Takeda, Tomotika Tanaka, Tadao Andoh, Ayumi Shinohara and Mami Nakata :
Evaluation of Antioxidant Activity of Environmental Plants: Activity of the Leaf Extracts from Seashore Plants,
Journal of Agricultural and Food Chemistry, Vol.47, No.4, 1749-1754, 1999.
(DOI: 10.1021/jf980864s)
124.Yasuo Oyama, Toshiya Masuda, Mami Nakata, Lumi Chikahisa, Yuko Yamazaki, Kumiko Miura and Makiko Okagawa :
Protective action of 5'-n-alkylated curcumins on living cells suffering from oxidative stress,
European Journal of Pharmacology, Vol.360, 65-71, 1998.
125.Toshiya Masuda, Hiroyuki Matsumura, Yasuo Oyama, Yoshio Takeda, Akiko Jitoe, Atsuko Kida and Kayo Hidaka :
Synthesis of (+-)-Cassumunins A and B, New Curcuminoid Antioxidants Having Protective Activity of the Living Cell against Oxidative Damage,
Journal of Natural Products, Vol.61, No.5, 609-613, 1998.
126.Yasuo Oyama, Mami Nakata, Mineshi Sakamoto, Lumi Chikahisa, Norikazu Miyoshi and Masaya Satoh :
Methylmercury toxicity in rat brain neurons: modificatons by compounds possessing SH-group and comparison with dimethylmercury, N-ethylmaleimide, and ionomycin,
Environmental Toxicology and Pharmacology, Vol.6, 221-227, 1998.
127.Yasuo Oyama, Lumi Chikahisa, Kaori Kanemaru, Mami Nakata, Sachi Noguchi, Takayuki Nagano, Eisuke Okazaki and Akira Hirata :
Cytotoxic actions of FTY720, a novel immunosuppressant, on thymocytes and brain neurons dissociated from the rat,
The Japanese Journal of Pharmacology, Vol.76, 377-385, 1998.
128.Lumi Chikahisa, Yasuo Oyama, Yoko Iguchi, Eisuke Okazaki, Norikazu Miyoshi, Masaya Satoh and Yuji Yamada :
Effects of triphenyltin on growth and viability of K562 leukemia cells,
Environmental Toxicology and Pharmacology, Vol.6, 209-215, 1998.
129.Takayuki Nagano, Yasuo Oyama, Noriko Kajita, Lumi Chikahisa, Mami Nakata, Eisuke Okazaki and Toshiya Masuda :
New curcuminoids isolated from Zingiber cassumunar protect cells suffering from oxidative stress: a flow cytometric study using rat thymocytes and H2O2,
The Japanese Journal of Pharmacology, Vol.75, No.4, 363-370, 1997.
130.Eisuke Okazaki, Yasuo Oyama, Lumi Chikahisa, Takayuki Nagano, Norikazu Katayama and Mineshi Sakamoto :
Fluorescent estimation on cytotoxicity of methylmercury in dissociated rat cerebellar neurons: its comparison with ionomycin,
Environmental Toxicology and Pharmacology, Vol.3, No.4, 237-244, 1997.
131.Yasuo Oyama, Chiharu Sadakata, Lumi Chikahisa, Takayuki Nagano and Eisuke Okazaki :
Flow-cytometric analysis on kinate-induced decrease in the cellular content of nonprotein thiols in dissociated rat brain neurons,
Brain Research, Vol.760, No.1-2, 277-280, 1997.
132.Toshiko Ueha, Yasuo Oyama and Fukiyo Tomiyoshi :
Cytotoxic action of tri-n-butyltin on cerebellar neurons dissociated from the rats: a flow cytometric study,
Pharmacology and Toxicology, Vol.78, No.6, 404-408, 1996.
(PubMed: 8829201)
133.Yasuo Oyama, David Carpenter, Lumi Chikahisa and Eisuke Okazaki :
Flow-cytometric estimation on glutamate- and kainate-induced increase in intracellular Ca2+ concentration of brain neurons,
Brain Research, Vol.728, No.1, 121-124, 1996.
134.Yasuo Oyama, Lumi Chikahisa, Toshiko Ueha, Kaori Kanemaru and Katuhiko Noda :
Ginkgo biloba extract protects brain neurons aganist oxidative stress induced by hydrogen peroxide,
Brain Research, Vol.712, No.2, 349-352, 1996.
135.Yasuo Oyama, Eisuke Okazaki, Lumi Chikahisa, Takayuki Nagano and Chiharu Sadakata :
Oxidative stress-induced increase in intracellular Ca2+ concentration and Ca2+-induced increase in oxidative stress: an experimental model using dissociated brain neurons,
The Japanese Journal of Pharmacology, Vol.72, No.4, 381-385, 1996.
(PubMed: 9015747)
136.Eisuke Okazaki, Lumi Chikahisa, Kaori Kanemaru and Yasuo Oyama :
Flow cytometric analysis on the H2O2-induced increase in intracellular Ca2+ concentration of rat thymocytes,
The Japanese Journal of Pharmacology, Vol.71, No.4, 273-280, 1996.
137.Lumi Chikahisa, Yasuo Oyama, Eisuke Okazaki and Katuhiko Noda :
Fluorescent estimation on H2O2-indiced chnages in cell viability and cellular nonprotein thiol level of dissociated rat thymocytes,
The Japanese Journal of Pharmacology, Vol.71, No.4, 299-305, 1996.
138.Yasuo Oyama, Lumi Chikahisa, Toshiko Ueha, Yoshiko Hatakeyama and Takuya Kokubun :
Change in membrane permeability induced by amyloid beta-protein fragment 25-35 in brain neurons dissociated from the rats,
The Japanese Journal of Pharmacology, Vol.68, No.1, 77-83, 1995.
139.Yasuo Oyama, David Carpenter, Shinya Ueno, Hiromi Hayashi and Fukiyo Tomiyoshi :
Methylmercury activates Ca2+-dependent K+ conductance of mouse thymocytes: a flow cytometric study using fluorescent dyes,
European Journal of Pharmacology, Vol.293, No.2, 101-107, 1995.
140.Yasuo Oyama, Toshiko Ueha, Akemi Hayashi and Lumi Chikahisa :
Effect of tri-n-butyltin on intracellular Ca2+ concentration of mouse thymocytes under Ca2+-free condition,
European Journal of Pharmacology, Vol.270, No.2-3, 137-142, 1994.
141.Yasuo Oyama, Lumi Chikahisa, Hideki Matoba and Katsuhiko Furukawa :
Attenuation of Ca2+-induced increase in oxidative metabolism by cooling and calmodulin antagonist in mammalian brain neuron,
Brain Research, Vol.664, No.1-2, 220-224, 1994.
142.Katsuhiko Furukawa, Yasuo Oyama, Lumi Chikahisa, Yoshiko Hatakeyama and Norio Akaike :
Flow cytometric analysis on cytotoxic action of amyloid beta-protein fragment 25-35 on brain neurons dissociated from rats,
Brain Research, Vol.660, No.1-2, 259-262, 1994.
143.Yasuo Oyama, Katsuhiko Furukawa, Lumi Chikahisa and Yoshiko Hatakeyama :
Effect of N,N-diethyldithiocarbamate on ionomycin-induced increase in oxidation of cellular 2,7-dichlorofluorescin in dissociated cerebellar neurons,
Brain Research, Vol.660, 158-161, 1994.
144.Yasuo Oyama, Fukiyo Tomiyoshi, Shinya Ueno, Katsutoshi Furukawa and Lumi Chikahisa :
Methylmercury-induced augmentation of oxidative metabolism in cerebellar neurons dissociated from the rats: its dependence on intracellualr Ca2+,
Brain Research, Vol.660, 154-157, 1994.
145.Yasuo Oyama, Paul Fuchs, Norihiro Katayama and Katuhiko Noda :
Myricetin and quercetin, the flavonoid constituents of Ginko biloba extract, greatly reduce oxidative metabolism in both resting and Ca2+-loaded brain neurons,
Brain Research, Vol.635, 125-129, 1994.
146.Yasuo Oyama, Akemi Hayashi, Toshiko Ueha and Katuhiko Noda :
Characterization of 2,7-dichlrorofluorescein fluorescence in dissociated mammalian brain neurons: estimation on intracellular content of hydrogen peroxide,
Brain Research, Vol.635, 113-117, 1994.
147.Yasuo Oyama, Akemi Hayashi and Toshiko Ueha :
Ca2+-induced increase in oxidative metabolism of dissociated mammalian brain neurons: effect of extrcat of Ginkgo biloba leaves,
The Japanese Journal of Pharmacology, Vol.61, 367-370, 1993.
148.Yasuo Oyama, Toshiko Ueha and Akemi Hayashi :
Effect of tri-n-butyltin on intracellular Ca2+ concentration of rat cerebellar neurons,
European Journal of Pharmacology, Vol.248, 89-93, 1993.
149.Norio Akaike, Hitoshi Ishibashi, Nobutoshi Harata, Yasuo Oyama and Toshiko Ueha :
Effects of KB-2796, a new dihydroptridine Ca2+-antagonist, on voltage-dependent Ca2+ currents and oxidative metabolism in dissociated mammalian CNS neurons,
Brain Research, Vol.619, 263-270, 1993.
150.Yasuo Oyama, Akemi Hayashi, Toshiko Ueha, Lumi Chikahisa and Katsutoshi Furukawa :
Fluorescent estimation on the effect of Ca2+-antagonist on the oxidative metabolism in dissocaited mammalian brain neurons,
Brain Research, Vol.610, 172-175, 1993.
151.Yasuo Oyama, Toshiko Ueha, Akemi Hayashi, Limi Chikahisa and Katuhiko Noda :
Flow cytometric estimation of the effect of Gingko biloba extract on the content of hydrogen peroxide in dissociated mammalian brain neurons,
The Japanese Journal of Pharmacology, Vol.60, 385-388, 1992.
152.Yasuo Oyama, Lumi Chikahisa, Katuhiko Noda, Hiromi Hayashi and Fukiyo Tomiyoshi :
Characterization of the triphenyltin-induced increase in intracellular Ca2+ of mouse thymocytes: comparison with the action of A23187,
The Japanese Journal of Pharmacology, Vol.60, 159-167, 1992.
153.Yasuo Oyama, Nobutoshi Harata and Norio Akaike :
Accelerating action of quinidine on the decay phase of transient outward current in dissociated hippocampal pyramidal neurons of rats,
The Japanese Journal of Pharmacology, Vol.58, No.2, 185-188, 1992.
154.Yasuo Oyama, Lumi Chikahisa, Akemi Hayashi, Toshiko Ueha, Mitsuhiro Sato and Hideki Matoba :
Triphenyltin-induced increase in the intracellular Ca2+ of dissocaited mammalian CNS neuron: its independence from voltage-dependent Ca2+ channesls,
The Japanese Journal of Pharmacology, Vol.58, 467-471, 1992.
155.Yasuo Oyama :
Modification of voltage-dependent Na+ current by triphenyltin, an environmental pollutant, in isolated mammalian brain neuons,
Brain Research, Vol.583, 93-99, 1992.
156.Lumi Chikahisa and Yasuo Oyama :
Tri-n-butyltin increases intracellular Ca2+ in mouse thymocytes: a flow cytometric study using fluorescent dyes for membrane potential and intracellular Ca2+,
Pharmacology and Toxicology, Vol.71, 190-195, 1992.
157.Yasuo Oyama, Lumi Chikahisa, Fukiyo Tomiyoshi and Hiromi Hayashi :
Cytotoxic action of triphenyltin on mouse thymocytes: a flow cytometric study using fluorescent dyes for membrane potential and intracellular Ca2+,
The Japanese Journal of Pharmacology, Vol.57, 419-424, 1991.
158.Yasuo Oyama, Nobutoshi Harata and Norio Akaike :
Rapid interaction of tetraethylammonium with delayed K+ channels in mammalian brain neuron,
Neuroscience Letters, Vol.131, 153-155, 1991.
159.Yasuo Oyama, Nobutoshi Harata and Norio Akaike :
Delayed potassium current and non-specific outward current in pyramidal neurons acutely isolated from rat hypocampus,
Brain Research, Vol.568, 350-354, 1991.
160.Yasuo Oyama, Toshio Nakaye, Norio Akaike and Katsuya Tsuchida :
Effect of CD349, a new dihydropyridine derivative Ca2+ antagonist, on the voltage-dependent Ca2+ currents in isolated brain neurons,
Archives internationales de Pharmacodymie et de Therapie, Vol.313, 47-62, 1991.
161.Yasuo Oyama and Norio Akaike :
Triphenyltin: a potent excitatory neurotoxicant. Its reciprocal effects on voltage-dependent Na+ and K+ currents of mammalian brain neuronss,
Neuroscience Letters, Vol.119, 261-264, 1990.
162.Yasuo Oyama, Nobuaki Hori, Charles Allen and David Carpenter :
Influence of trypsin and collagenase on acetylcholine responses of physically-isolated single neurons of Aplysia californica,
Cellular and Molecular Neurobiology, Vol.10, 198-205, 1990.
163.Junichi Sadoshima, Yasuo Oyama and Norio Akaike :
Inhibition of nicotinic acetylcholine response by atropine in frog isolated sympathetic neurons,
Brain Research, Vol.508, 147-151, 1990.
164.Yasuo Oyama, Yoshimi Ikemoto, Karel Kits and Norio Akaike :
GABA affects the glutamate receptor-chloride channel complex in mechanically-isolated and internally-perfused Aplysia neurons,
European Journal of Pharmacology, Vol.185, No.1, 43-52, 1990.
(DOI: 10.1016/0014-2999(90)90209-O,   PubMed: 1699768,   Elsevier: Scopus)
165.Norio Akaike, Yasuo Oyama and Takashi Yakushiji :
Influences of external Ca2+ on the GABA-induced chloride current and the efficacy of diazepam in internally-perfused frog sensory neuronss,
Brain Research, Vol.504, 293-296, 1989.
166.Satoru Ishizuka, Sujit Sikdar, Shozo Yasui, Yasuo Oyama and Norio Akaike :
Alpha-chloralose opens the chloride channel of frog isolated sensory neurons,
Brain Research, Vol.498, 181-184, 1989.
167.Minoru Wakamori, Makoto Kaneda, Yasuo Oyama and Norio Akaike :
Effects of chlorodiazepoxide, chlorpromazine, diazepam, diphenylhydantoin, flunitrazepam, and haloperidol on the voltage-dependent sodium current of isolated mammalian brain neurons,
Brain Research, Vol.494, 374-378, 1989.
168.Takashi Yakushiji, Yasuo Oyama and Norio Akaike :
Comparative study on barbiturates using isolated single neurons: GABA-mimetic action and augmentatory action on GABA response,
Brain Research, Vol.488, 357-360, 1989.
169.Takashi Yakushiji, Takemi Fukuda, Yasuo Oyama and Norio Akaike :
Effects of benzodiazepines and non-benzodiazepine compounds on the GABA-induced response in frog isolated sensory neurons,
British Journal of Pharmacology, Vol.98, 735-740, 1989.
170.Yasuo Oyama, Nobuaki Hori, Macheal Evans, Charles Allen and David Carpenter :
Electrophysiological estimation of actions of acetylcholinestrase inhibitors on acetylcholine receptor and cholinestrase in physically-isolated Aplysia neurons,
British Journal of Pharmacology, Vol.96, 573-582, 1989.
171.Makoto Kaneda, Yasuo Oyama, Yoshimi Ikemoto and Norio Akaike :
Scorpion toxin prolongs an inactivation phase of the voltage-dependent sodium current in rat isolated single hippocampal neurons,
Brain Research, Vol.487, 192-195, 1989.
172.Makoto Kaneda, Yasuo Oyama, Yoshimi Ikemoto and Norio Akaike :
Blockade of the voltage-dependent sodium current in isolated rat hippocampal neurons by tetrodotoxin and lidocaine,
Brain Research, Vol.484, 348-351, 1989.
173.Norio Inomata, Naofumi Tokutomi, Yasuo Oyama and Norio Akaike :
Intracellular picrotoxin blocks pentobarbital-gated Cl- conductance,
Neuroscience Research, Vol.6, No.1, 72-75, 1988.
174.Norio Akaike, Yasuo Oyama and Naofumi Tokutomi :
Inhibition of drug-gated chloride currents by calcium influx in frog sensory neurons,
Neuroscience Research, Vol.5, 557-562, 1988.
175.Yasuo Oyama, Wein King, Norio Akaike and David Carpenter :
Characterization of an inward current elicited by edrophonium in physically-isolated and internally-perfused Aplysia neurons,
Brain Research, Vol.438, 124-132, 1988.
176.Yasuo Oyama, Martin Evans, Norio Akaike and David Carpenter :
Electrophysiological detection of acetylcholinestrase activity using concentration clamp on physically-isolated Aplysia neurons,
Neuroscience Research, Vol.6, 174-180, 1988.
177.Norio Akaike, Yasuo Tsuda and Yasuo Oyama :
Separation of current- and voltage-dependent inactivation of calcium currents in frog sensory neurons,
Neuroscience Letters, Vol.84, 46-50, 1988.
178.Yasuo Oyama, Junichi Sadoshima, Naofumi Tokutomi and Norio Akaike :
Some properties of inhibitory action of lidocaine on the Ca2+ current of single isolated frog sensory neurons,
Brain Research, Vol.442, 223-226, 1988.
179.Yasuo Oyama, Norio Akaike and David Carpenter :
Strychinine decreases the voltage-dependent Ca2+ current of both Aplysia and frog ganglion neurons,
Cellular and Molecular Neurobiology, Vol.8, 307-314, 1988.
180.Yasuo Tsuda, Yasuo Oyama, David Carpenter and Norio Akaike :
Effects of Ca2+ on the transient outward current of single isolated Helix central neurons,
British Journal of Pharmacology, Vol.95, 526-530, 1988.
181.Yasuo Oyama, Wein King and David Carpenter :
Edrophonium-induced inward membrane current in single neurons physically-isolated from Aplysia californica,
Brain Research, Vol.438, 95-100, 1988.
182.Yasuo Oyama, Yasuo Tsuda, Shunpei Sakakibara and Norio Akaike :
Synthetic omega-conotoxin: a potent calcium channel blocking neurotoxin,
Brain Research, Vol.424, 58-64, 1987.
183.Yasuo Oyama, Nobuaki Hori, Naofumi Tokutomi and Norio Akaike :
D-600 blocks open Ca2+ channels more profoundly than closed ones,
Brain Research, Vol.417, 143-147, 1987.
184.Yasuo Oyama :
Some membrane characteristic of single isolated nodose ganglion cells studied under current and voltage clamp conditions,
Brain Research, Vol.410, 61-68, 1987.
185.Yasuo Oyama :
Actions of convulsants, 5-aminopyridine and pentylenetetrazole, on the transient outward current of single isolated nodose ganglion neurons,
Brain Research, Vol.409, 243-249, 1987.
186.Yasuo Oyama and John Walker :
Inhibitory action of furosemide on the active chloride transport of papillary heart muscle in rabbit,
European Journal of Pharmacology, Vol.123, 85-90, 1986.
187.Yasuo Oyama, Norio Akakie and Katsuhide Nishi :
Persistent calcium inward current in internally-perfused snail neuron,
Cellular and Molecular Neurobiology, Vol.6, 71-85, 1986.
188.Yasuo Oyama and Shunsuke Kuraoka :
Some differences in ionic and pharmacological blocking actions on the currents through Ca2+ channels in a molluscan neuron,
Archives internationales de Pharmacodymie et de Therapie, Vol.281, 230-239, 1986.
189.Yasuo Oyama, John Walker and Carlos Eyzaguirre :
Intracellular potassium activity, potassium equilibrium potential and membrane potential of carotid body glomus cells,
Brain Research, Vol.381, 405-408, 1986.
190.Yasuo Oyama, Norio Akaike and Katsuhide Nishi :
Effects of n-alkanols on the calcium current of intracellularly perfused neurons of Helix aspersa,
Brain Research, Vol.376, 280-284, 1986.
191.Yasuo Oyama, John Walker and Carlos Eyzaguirre :
The intracellular chloride activity of glomus cells in the isolated carotid body,
Brain Research, Vol.368, 167-169, 1986.
192.Akira Hirata, Hiroshi Yoshida, Yasuo Oyama and Norio Akaike :
Hypokalemia modulates alpha- and beta-adrenoceptor bindings in rat skeletal muscle,
Cellular and Molecular Neurobiology, Vol.6, 255-262, 1986.
193.Yasuo Oyama, Norio Akaike, Shunsuke Kuraoka and Katsuhide Nishi :
Differences in the actions of organic and inorganic Ca2+-antagonists on the inactivation of the Ca2+ channels in a molluscan neuron,
Comparative Biochemistry and Physiology, Vol.83, 353-357, 1986.
194.Norio Akakie and Yasuo Oyama :
Contribution of restricted extrcaellular space to the inactivation of calcium current in the snail neuron,
Neuroscience Research, Vol.2, 181-188, 1985.
195.Norio Akaike, Atsuko Yatani, Katsuhide Nishi, Yasuo Oyama and Shunsuke Kuraoka :
Permeability to various cations of the voltage-dependent sodium channel of rat single heart cells,
The Journal of Pharmacology and Experimental Therapeutics, Vol.228, 245-255, 1984.
196.Katsuhide Nishi and Yasuo Oyama :
Barbiturates increase the rate of voltage-dependent inactivation of the calcium current in snail neurons,
British Journal of Pharmacology, Vol.80, 761-765, 1983.
197.Katsuhide Nishi, Norio Akaike, Yasuo Oyama and Hirosumi Ito :
Actions of calcium antagonists on calcium current in Helix neurons. Specifity and potency,
Circulation Research, Vol.52, 153-159, 1983.
198.Norio Akaike, Akira Hirata, Toshikazu Kiyohara and Yasuo Oyama :
Neural regulation on the active sodium-potassium transport in hypokalemic rat skeltal muscle,
The Journal of Physiology, Vol.341, 245-255, 1983.
199.Norio Akaike, Katsuhide Nishi and Yasuo Oyama :
Characteristics of manganese current and its comparison with currents carried by other divalent cations in snail soma membranes,
The Journal of Membrane Biology, Vol.76, 323-336, 1983.
200.Norio Akaike, Toshikazu Kiyohara and Yasuo Oyama :
Quantitative in vivo studies on the active Na+-K+ transports in "tonic" muscle of the hypokalemic rat,
The Japanese Journal of Physiology, Vol.33, 323-336, 1983.
201.Katsuhide Nishi and Yasuo Oyama :
Accelerating effects of pentobaribitone on the inactivation process of the calcium current in Helix neurones,
British Journal of Pharmacology, Vol.79, 645-654, 1983.
202.Norio Akaike, Hirosumi Ito, Katsuhide Nishi and Yasuo Oyama :
Further analysis of inhibitory effects of propranolol and local anaesthetics on the calcium current of Helix neurones,
British Journal of Pharmacology, Vol.76, 37-43, 1982.
203.Yoshitoshi Kase, Hakaru Seo, Yasuo Oyama, Moriyuki Sakata, Katsumi Tomoda, Kazuo Takahama, Taizo Hitoshi, Yoshiro Okano and Takeshi Miyata :
A new method for evaluating mucolytic expectorant activity aand its application. II. Application to two proteolytic enzymes, seratiopeptidase and seaprose,
Arzneimittel-Forschung, Vol.32, 374-378, 1982.
204.Yoshitoshi Kase, Hakaru Seo, Yasuo Oyama, Moriyuki Sakata, Katsumi Tomoda, Kazuo Takahama, Taizo Hotoshi, Yoshiro Okano and Takeshi Miyata :
A new method for evaluating mucolytic expectorant activity and its application. I. Methodology,
Arzneimittel-Forschung, Vol.32, 368-373, 1982.
205.Yasuo Oyama, Katsuhide Nishi, Atsuko Yatani and Norio Akaike :
Zinc current in Helix soma membrane,
Comparative Biochemistry and Physiology, Vol.72, 403-410, 1982.
206.Katsuhide Nishi, Yasuo Oyama and Yasufumi Nishizono :
Effect of antiarrythmic agents on the sodium current of myocardium analyzed in isolated single mammalian cardiac cells,
Japanese Heart Journal, Vol.23, 75-77, 1982.
207.小山 保夫, 伊藤 博澄, 六反田 学, 西 勝英 :
ブニトロロールのカルシウム拮抗作用に関する検討,
熊本医学会雑誌, Vol.55, 191-195, 1981年.
208.Norio Akaike, Katsuhide Nishi and Yasuo Oyama :
Inhibitory effects of propranolol on the calcium current of Helix neurones,
British Journal of Pharmacology, Vol.73, 431-434, 1981.
209.Matao Sakanashi, Eiji Tomomatsu, Rinko Fukai, Yasuo Oyama, Shoji Ueda, Fumio Takenaka and Makie Higuchi :
Analysis of vasodilatatory action of a new nitroester agent, 2-nicotinamideethyl nitrate (SG-75),
Arzneimittel-Forschung, Vol.29, 1530-1533, 1979.
210.高浜 和夫, 鬼頭 剛, 小山 保夫, 宮田 健, 加瀬 佳年 :
呼吸興奮作用をもつ鎮咳薬 Forminoben の鎮咳作用ならびにこれと関連する薬理作用,Benproperine,Isoaminile との比較,
応用薬理, Vol.16, 23-32, 1978年.
211.加瀬 佳年, 高浜 和夫, 瀬尾 量, 広津 一郎, 鬼頭 剛, 宮田 健, 小山 保夫, 池田 和夫 :
Procaterol (OPC-2009) およびその誘導体(OPC-2030)の気道系に対する効果,
応用薬理, Vol.15, 705-720, 1978年.
(Elsevier: Scopus)
212.加瀬 佳年, 池上 幸三郎, 鬼頭 剛, 小山 保夫, 高浜 和夫, 宮田 健, 久保 真治 :
Dihydrocodeine の鎮咳および他の薬理効果に及ぼす chloropheniramine および methylephedrine 配合の効果,
応用薬理, Vol.15, 408-418, 1978年.
213.鬼頭 剛, 高浜 和夫, 小山 保夫, 岡野 善郎, 加瀬 佳年 :
呼吸興奮作用をもつ鎮咳薬 3-chlor-2-{N-methyl-N-[(morpholino-carbonyl)methyl]aminomethyl}benzalinide (Forminobenm, PB-89) の鎮咳効果の作用点,
応用薬理, Vol.15, 375-383, 1978年.

学術論文(紀要・その他):

1.Hiroko Matsui, Yoko Sakanashi, Yumiko Nishimura, Kanna Horimoto, Kaori Kanemaru, Shiro Ishida, Yoshiro Okano and Yasuo Oyama :
Cremophor EL modifies adriamycin-induced action on human leukemia K562 cells,
Natural Science Research, Vol.21, 9-17, 2007.
(CiNii: 110006839863)
2.Masako Kobayashi, Yoko Sakanashi, Hiroko Matsui, Yumiko Nishimura, Kaori Kanemaru, Yoshiro Okano and Yasuo Oyama :
Micromolar zinc modifies the cell death induced by clotrimazole in human leukemia K562 cells,
Natural Science Research, Vol.21, 1-8, 2007.
(CiNii: 110006839852)
3.Masaya Satoh, Yoko Tanaka and Yasuo Oyama :
Nonprotein thiol levels and susceptibility to HgCl2 of harmful phytoplankton Heterocapsa circularisquama (Dinophyceae),
Natural Science Research, Faculty of Integrated Arts and Sciences, The University of Tokushima, Vol.17, 53-61, 2003.
4.野田 克彦, 金丸 芳, 小山 保夫 :
レタス種子の生育に及ぼすナトリウムの影響,
徳島大学総合科学部自然科学研究, Vol.17, 63-67, 2003年.
5.Hiromi Nakao, Toshiko Ueha-Ishibashi, Chisato Umebayashi and Yasuo Oyama :
Actions of thimerosal on growth and viability of K562 human leukemia cells: Comparison with those of methylmercury,
Natural Science Research, Vol.17, 43-52, 2003.
6.Hiromi Nakao, Yoshimi Narita, Lumi Chikahisa-Muramatu, Chisato Umebayashi, Kaori Kanemaru, Yasuo Oyama, Shiro Ishida and Okano Yoshiro :
Further characterization of buthionine sulfoximine-induced potentiation of As2O3 cytotoxicity in human leukemia K562 cells: a flow cytometric study,
Natural Science Research, Vol.17, 27-41, 2003.
7.近久 ルミ, 小山 保夫, 高濱 和夫 :
フローサイトメーターによる細胞毒性評価方法の確立,
徳島大学総合科学部自然科学研究, Vol.15, No.0, 37-68, 2002年.
(CiNii: 110000503468)
8.Yoshimi Narita, Yasuo Oyama, Tomohiro Arata, Kaori Kanemaru and Yoshiro Okano :
Potentiation of As2O3-induced cytotoxicity by buthionine sulfoximine in human leukemia K562 cells,
Natural Science Research, Vol.15, 21-34, 2002.
9.Noriko Kajita, Lumi Chikahisa, Yuko Yamazaki, Norihiko Akaike, Kaori Kanemaru, Hitomi Sakai, Katuhiko Noda and Yasuo Oyama :
Effects of the agents affecting membrane potassium permeability on growth and viability in human leukemia K562 cells,
Natural Science Research, Vol.14, 35-46, 2001.
10.Yoshihiko Okada, Yasuo Oyama, Toshiko Ueha-Ishibashi, Kaori Kanemaru, Norihiko Akaike, Norikazu Miyoshi and Masaya Satoh :
Cytotoxic action of tri-n-butyltin hydride, a nucleaphilic triorganotin, on rat thymocytes: a flow cytometric study,
Natural Science Research, Vol.14, 21-34, 2001.
11.Yasuo Oyama, Yoshihiko Okada, Norihiko Akaike, Kaori Kanemaru, Yumiko Kanemoto, Lumi Chikahisa, Masaya Satoh and Hiromi Hayashi :
Protective action of tri-n-butyltin on the cells suffering from oxidative strss: Its implication in bioaccumulation,
Natural Science Research, Vol.14, 9-20, 2001.
12.Yuko Yamazaki, Mami Nakata, Noriko Kajita, Megumi Funai, Sachi Noguchi, Yasuo Oyama, Norikazu Miyoshi and Masaya Satoh :
Effects of organic and inorganic mercuries on growth and viability of K562 human leukemia cells,
Natural Science Research, Vol.12, 15-26, 1999.
13.Yasuo Oyama :
Effects of triorganotins on brain neurons, thymocytes and tumor cells,
Journal of Toxicological Sciences, Vol.23, 379, 1998.
14.Kaori Kanemaru, Yasuo Oyama, Lumi Chikahisa, Mami Nakata, Takayuki Nagano, Eisuke Okazaki, Katuhiko Noda and Toshiya Masuda :
Protection of brain neuronss suffering from oxidative stress by new curcuminoids isolated from Zingiber cassumunar,
Natural Science Research, Vol.11, 7-19, 1998.
15.Eisuke Okazaki, Toshiko Ueha, Lumi Chikahisa, Takayuki Nagano, Chiharu Sadakata, Takuya Kokubun and Yasuo Oyama :
Pharmacological property of Ca2+ waves in ventricular myocytes dissociated from rat hearts,
Natural Science Research, Vol.10, 1-9, 1997.

学術レター:

1.Tomohiro Oyama, Eri Fukunaga and Yasuo Oyama :
Cell death process induced by hydrogen peroxide is accelerated by clioquinol in rat thymocytes,
Natural Science Research, Vol.29, No.3, 31-33, 2015.
(徳島大学機関リポジトリ: 111008,   CiNii: 110010016078)
2.Eri Fukunaga, Yurie Ohiwa, Mari Yamada, Ayaka Sumi, Masaya Satoh and Yasuo Oyama :
Effects of N,N-dimethyldodecylamine-N-oxide on some cellular parameters of rat thymocytes,
Natural Science Research, Vol.29, No.1, 1-4, 2015.
(徳島大学機関リポジトリ: 111004,   CiNii: 40021282491)
3.Shoehei Saitoh, Eri Fukunaga, Sari Honda, Kaori Kanemaru, Masaya Satoh and Yasuo Oyama :
Nonivamide, a natural analog of capsaicin, affects intracellular Ca2+ level in rat thymic lymphocytes,
Natural Science Research, Vol.28, No.3, 15-19, 2014.
(徳島大学機関リポジトリ: 106432,   CiNii: 110009915549)
4.Eri Fukunaga and Yasuo Oyama :
Effects of tetracaine and lidocaine on intracellular Zn2+ levels in rat neurons: Preliminary analysis with FluoZin-3 fluorescence,
Natural Science Research, Vol.28, No.1, 1-5, 2014.
(徳島大学機関リポジトリ: 106430)

国際会議:

1.Masaya Satoh and Yasuo Oyama :
Nonprotein thiols and ascorbate in phytoplankton: Relationship between their cellular concentrations and tolerance against oxidative stress and heavy metals,
The 5gh Asia-Pacific Conference on Algal Biotechnology, Qingdao, Oct. 2003.
2.Masaya Satoh and Yasuo Oyama :
Antioxidant molecules of phytoplankton: quantification and physiological aspects of glutathione, cysteine and ascorbic acid,
Algae2002, Tsukuba, Jul. 2002.
3.Masaya Satoh and Yasuo Oyama :
Nonprotein thiols in microalgae: their quantity and roles,
Phycology Toward The 21st Century, Yamagata, Jun. 2001.

国内講演発表:

1.Badr Ali Hoida, Takahashi Keiko, Ryushi Kawakami, Yasuo Oyama, Kumio Yokoigawa and Kaori Kanemaru :
Screening and analysis of edible seaweeds in the ability to adsorb Shiga toxin,
第38回日本日本食品微生物学会学術総会, Oct. 2017.
2.生杉 笙, 金丸 芳, 横井川 久己男, 小山 保夫 :
徳島県産食用植物クサギClerodendrum trichotomunのガン細胞増殖抑制,
日本農芸化学会中国四国支部第48回講演会講演要旨, 33, 2017年6月.
3.金丸 芳, 生杉 笙, 川上 竜巳, 小山 保夫, 横井川 久己男 :
徳島県産食用植物のガン細胞増殖抑制,
日本農芸化学会2017年度(平成29年度)大会講演要旨集, 109, 2017年3月.
4.高橋 啓子, 服部 武文, 金丸 芳, 小山 保夫, 横井川 久己男 :
Tricholoma matsutake 菌糸生育におけるD-及びL-アミノ酸の添加効果,
日本農芸化学会中四国支部第45回講演会要旨集, 36, 2016年6月.
5.新開 愛美, 藤本 彩, 小山 保夫, 中村 光裕, 前川 智美, 曽根 良昭, 増田 俊哉 :
ゴマ抗酸化フェノール・セサモール酸化物の構造と細胞毒性,
第53回天然有機化合物討論会講演要旨集, 277-282, 2011年9月.
6.新開 愛美, 藤本 彩, 中村 光裕, 増田 俊哉, 小山 保夫 :
ペルオキシ結合を有する特異なセサモール酸化ダイマーの構造ー酸化生成物の構造と機能IV,
日本農芸化学会中四国支部第28回講演会, 62, 2010年9月.
7.新開 愛美, 藤本 彩, 小山 保夫, 前川 智美, 曽根 良昭, 増田 俊哉 :
セサモールダイマーの構造とその細胞毒性の評価ー抗酸化フェノール物質の酸化生成物の構造と機能III,
2010年度大会講演要旨集, 149, 2010年3月.
8.藤本 彩, 小山 保夫, 増田 俊哉 :
抗酸化性フェノール物質の酸化生成物の構造と機能 細胞毒性を有するセサモール酸化物の構造,
日本農芸化学会21年度大会講演要旨集, 21, 2009年3月.
9.篠山 優也, 金丸 芳, 小山 保夫, 林 弘三 :
シンナムアルデヒドのガン細胞増殖抑制,
平成15年度日本農芸化学会西日本支部,中四国支部.日本栄養·食糧学会西日本支部,日本食品科学工学会西日本支部鹿児島合同大会およびシンポジウム, 2003年9月.
10.佐藤 征弥, 越智 美幸, 小山 保夫 :
微細藻類のビタミンC量とH2O2感受性について,
日本藻類学会第27会大会, 2003年3月.
11.佐藤 征弥, 小山 保夫 :
植物プランクトンの nonprotein thiol について,
徳島生物学会第107回総会, 2002年9月.
12.佐藤 征弥, 吉岡 愛, 小林 真紀, 浦本 陽華, 小山 保夫 :
微細藻類における細胞内チオール量と水銀耐性及び酸化ストレスとの関係,
日本植物学会第65回大会, 2001年9月.
13.金丸 芳, 工野 良子, 小西 ユカリ, 酒井 仁美, 小山 保夫, 中川 秀幸, 林 弘三, 野田 克彦 :
H2O2障害に対するヒジキの胸腺細胞保護作用,
日本食品科学工学会第48回大会, 2001年9月.
14.金丸 芳, 小西 ユカリ, 工野 良子, 佐藤 征弥, 小山 保夫, 林 弘三, 酒井 仁美, 中川 秀幸, 野田 克彦 :
ガン細胞増殖抑制活性を有する海藻の検索,
日本農芸化学会2001年度大会, 2001年3月.
15.佐藤 征弥, 平地 義伸, 吉岡 愛, 小林 真紀, 小山 保夫 :
微細藻類における細胞内チオール量と重金属耐性について,
日本植物学会第64回大会, 2000年9月.
16.佐藤 征弥, 平地 義伸, 向井 真弓, 小山 保夫 :
プラシノ藻類及びハプト藻類の細胞内チオールの定量,
日本藻類学会第24回大会, 2000年3月.
17.佐藤 征弥, 高島 由希, 濱崎 静恵, 小山 保夫 :
プラシノ藻類 Tetraselmis tetrathele における重金属結合性ペプチドの動態,
日本藻類学会第23回大会, 1999年3月.
18.小山 保夫, 梶田 紀子, 中田 真美, 山崎 優子, 船井 めぐみ, 野口 さち, 金丸 芳, 近久 ルミ :
バリノマイシンのK562細胞増殖抑制作用,
日本薬理学雑誌(第51回日本薬理学会西南部会), Vol.113, No.3, 68, 1998年11月.
19.金丸 芳, 鈴木 恵美, 柴田 真美子, 林 弘三, 野田 克彦, 小山 保夫 :
酸化ストレスに対する香辛料の細胞保護作用,
日本農芸化学会1998年度大会, 1998年4月.
20.佐藤 征弥, 梯 麻美子, 唐木 恵美, 小山 保夫 :
プラシノ藻類 Tetraselmis tetrathele における重金属結合性ペプチドの解析,
日本藻類学会第22回大会, 1998年3月.
21.小山 保夫, 中田 真美, 梶田 紀子, 近久 ルミ, 岡崎 英佐, 金丸 芳, 増田 俊哉 :
新規クルクミノイドの酸化ストレスに対する細胞保護作用,
日本薬理学雑誌(第50回日本薬理学会西南部会), Vol.111, No.2, 83, 1997年11月.
22.佐藤 征弥, 高島 由希, 濱崎 静恵, 小山 保夫 :
プラシノ藻類 Tetraselmis tetrathele における重金属処理による細胞内チオールレベルの変化,
日本植物学会第61回大会, 1997年9月.
23.佐藤 征弥, 高島 由希, 濱崎 静恵, 小山 保夫 :
重金属処理によるプラシノ藻類 Tetraselmis tetrathele 細胞内チオール濃度の変化,
日本藻類学会第21回大会, 1997年3月.

科学研究費補助金 (KAKEN Grants Database @ NII.ac.jp)

  • 細胞内亜鉛イオンによる化学物質の細胞毒性の増強・抑制メカニズム解析 (研究課題/領域番号: 26340039 )
  • 化学的ストレスによる細胞死に於ける亜鉛イオンの毒性科学的役割について (研究課題/領域番号: 23510078 )
  • 貝類に蓄積しているトリブチル錫などの有機錫の多様な毒性の解析 (研究課題/領域番号: 12680544 )
  • Amyloid β-protein fragmentによる細胞膜の透過性の解析 (研究課題/領域番号: 07670109 )
  • 有機金属化合物による細胞内Caイオン濃度の持続的上昇の解析 (研究課題/領域番号: 06680509 )
  • 単離した中枢神経細胞を用いる神経毒性の簡便な評価法の開発 (研究課題/領域番号: 03807009 )
  • 新キノロン剤による痙攣発作の発現機序に関する研究 (研究課題/領域番号: 02807213 )
  • 中枢神経単離ニュ-ロンにおけるグリシン受容器電位発生機構の巨視的および微視的解析 (研究課題/領域番号: 63480107 )
  • 細胞内遊離CaイオンによるGABA受容器・CCチャネル複合体の制御機構 (研究課題/領域番号: 01641530 )
  • 研究者番号(80214229)による検索