{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/18545936","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-51649109340&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=193381","label":"url"}],"paper_title":{"en":"Glycosidic Constituents of the Leaves of an Okinawan Leguminosae Plant, Derris trifoliate Lour","ja":"Glycosidic Constituents of the Leaves of an Okinawan Leguminosae Plant, Derris trifoliate Lour"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Yano Kaori"},{"name":"Ayaba Hisao"},{"name":"Masuda Toshiya"},{"name":"Otuka Hideaki"},{"name":"Seuyoshi Etsuko"},{"name":"Aramoto Mitsunori"}],"ja":[{"name":"武田 美雄"},{"name":"Yano Kaori"},{"name":"Ayaba Hisao"},{"name":"増田 俊哉"},{"name":"Otuka Hideaki"},{"name":"Seuyoshi Etsuko"},{"name":"Aramoto Mitsunori"}]},"description":{"en":"From the leaves of Derris trifoliata, collected in Okinawa, 15 glycosidic compounds were isolated and identified.","ja":"From the leaves of Derris trifoliata, collected in Okinawa, 15 glycosidic compounds were isolated and identified."},"publication_date":"2008-06-11","publication_name":{"en":"Journal of Natural Medicines","ja":"Journal of Natural Medicines"},"volume":"Vol.62","number":"No.4","starting_page":"476","ending_page":"478","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s11418-008-0263-y"],"issn":["1861-0293"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/18404346","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=172642","label":"url"}],"paper_title":{"en":"A new phenolic glucoside from an Uzbek medicinal plant, Origanum tyttanthum","ja":"A new phenolic glucoside from an Uzbek medicinal plant, Origanum tyttanthum"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Tomonari Maki"},{"name":"Arimoto Shihoko"},{"name":"Masuda Toshiya"},{"name":"Otsuka Hideaki"},{"name":"Matsunami Katsuyoshi"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takaishi Yoshihisa"},{"name":"Kiuchi Fumiyuki"},{"name":"Khodzhimatov K. Olimjon"},{"name":"Ashurmetov A. Ozodbek"}],"ja":[{"name":"武田 美雄"},{"name":"Tomonari Maki"},{"name":"Arimoto Shihoko"},{"name":"増田 俊哉"},{"name":"Otsuka Hideaki"},{"name":"Matsunami Katsuyoshi"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"高石 喜久"},{"name":"Kiuchi Fumiyuki"},{"name":"Khodzhimatov K. Olimjon"},{"name":"Ashurmetov A. Ozodbek"}]},"description":{"en":"A new phenolic glucoside was isolated from the aerial parts of Origanum tyttanthum, an Uzbek medicinal plant, together with 12 known compounds. The structure of the new compound was elucidated as 4-O-beta-D-glucopyranosylbenzyl-3'-hydroxyl-4'-methoxybenzoate (1) based on the spectral and chemical evidence.","ja":"A new phenolic glucoside was isolated from the aerial parts of Origanum tyttanthum, an Uzbek medicinal plant, together with 12 known compounds. The structure of the new compound was elucidated as 4-O-beta-D-glucopyranosylbenzyl-3'-hydroxyl-4'-methoxybenzoate (1) based on the spectral and chemical evidence."},"publication_date":"2008-01-10","publication_name":{"en":"Journal of Natural Medicines","ja":"Journal of Natural Medicines"},"volume":"Vol.62","number":"No.1","starting_page":"71","ending_page":"74","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s11418-007-0187-y"],"issn":["1861-0293"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/18052129","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=176570","label":"url"}],"paper_title":{"en":"Sesquiterpene Lactone from the Roots of Ferula varia and Their Cytotoxic Activity,","ja":"Sesquiterpene Lactone from the Roots of Ferula varia and Their Cytotoxic Activity,"},"authors":{"en":[{"name":"Suzuki Kyoko"},{"name":"Okasaka Mamoru"},{"name":"Kashiwada Yoshiki"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodshimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"},{"name":"Sekiya Michiko"},{"name":"Ikeshiro Yasumasa"}],"ja":[{"name":"鈴木 恭子"},{"name":"岡坂 衛"},{"name":"柏田 良樹"},{"name":"高石 喜久"},{"name":"本多 義昭"},{"name":"伊藤 美千穂"},{"name":"武田 美雄"},{"name":"Kodshimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"},{"name":"関谷 倫子"},{"name":"池城 安正"}]},"description":{"en":"The ethyl acetate-soluble fraction from a MeOH extract of the roots of Ferula varia gave six new sesquiterpene lactones (1-6) and five known sesquiterpenes (7-11). Their structures were established on the basis of spectroscopic evidence. The cytotoxic activities of 1-11 were evaluated against selected human cancer cell lines. Compound 4 showed significant selective cytotoxicity against multidrug-resistant cancer cells (KB-C2). The cytotoxicities of compounds 1, 3, 5, 8, and 11 against KB-C2 cells were enhanced in the presence of nontoxic concentrations of colchicine.","ja":"The ethyl acetate-soluble fraction from a MeOH extract of the roots of Ferula varia gave six new sesquiterpene lactones (1-6) and five known sesquiterpenes (7-11). Their structures were established on the basis of spectroscopic evidence. The cytotoxic activities of 1-11 were evaluated against selected human cancer cell lines. Compound 4 showed significant selective cytotoxicity against multidrug-resistant cancer cells (KB-C2). The cytotoxicities of compounds 1, 3, 5, 8, and 11 against KB-C2 cells were enhanced in the presence of nontoxic concentrations of colchicine."},"publication_date":"2007-12","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.70","number":"No.12","starting_page":"1915","ending_page":"1918","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np0703996"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/110006437258/","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/17978519","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001204169964672/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=172640","label":"url"}],"paper_title":{"en":"Tricalysioside P-U: Ent-kaurane glucosides and a labdane glucoside from leaves of Tricalysia dubia Ohwi","ja":"Tricalysioside P-U: Ent-kaurane glucosides and a labdane glucoside from leaves of Tricalysia dubia Ohwi"},"authors":{"en":[{"name":"Hideaki Otsuka"},{"name":"Junko Shitamoto"},{"name":"Dong-Hui He"},{"name":"Katsuyoshi Matsunami"},{"name":"Takakazu Shinzato"},{"name":"Mitsunori Aramoto"},{"name":"Takeda Yoshio"},{"name":"Tripetch Kanchanapoom"}],"ja":[{"name":"Hideaki Otsuka"},{"name":"Junko Shitamoto"},{"name":"Dong-Hui He"},{"name":"Katsuyoshi Matsunami"},{"name":"Takakazu Shinzato"},{"name":"Mitsunori Aramoto"},{"name":"武田 美雄"},{"name":"Tripetch Kanchanapoom"}]},"description":{"en":"Further extensive isolation work on the 1-BuOH-soluble fraction of a MeOH extract of Tricalysia dubia afforded five new ent-kaurane glucosides (4-8) and one new labdane glucoside (9), together with a known megastigmane glucoside, sammangaoside B (1), and monoterpene glucosides (2, 3). The structures of the new compounds were elucidated by analyses of one- and two-dimensional NMR spectroscopic data. The absolute configuration of the 9-position of sammangaoside B was revised to S and its total stereochemistry was established by the modified Mosher's method.","ja":"Further extensive isolation work on the 1-BuOH-soluble fraction of a MeOH extract of Tricalysia dubia afforded five new ent-kaurane glucosides (4-8) and one new labdane glucoside (9), together with a known megastigmane glucoside, sammangaoside B (1), and monoterpene glucosides (2, 3). The structures of the new compounds were elucidated by analyses of one- and two-dimensional NMR spectroscopic data. The absolute configuration of the 9-position of sammangaoside B was revised to S and its total stereochemistry was established by the modified Mosher's method."},"publication_date":"2007-11-01","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.55","number":"No.11","starting_page":"1600","ending_page":"1605","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.55.1600"],"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=172636","label":"url"}],"paper_title":{"en":"Bridelioside, a new lignan glycoside from Bridelia glauca Bl. f. balansae (Tucht.) Hatushima","ja":"Bridelioside, a new lignan glycoside from Bridelia glauca Bl. f. balansae (Tucht.) Hatushima"},"authors":{"en":[{"name":"Etsuko Sueyoshi"},{"name":"Hui Liu"},{"name":"Katsuyoshi Matsunami"},{"name":"Hideaki Otsuka"},{"name":"Takakazu Shinzato"},{"name":"Mitsunori Aramoto"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Etsuko Sueyoshi"},{"name":"Hui Liu"},{"name":"Katsuyoshi Matsunami"},{"name":"Hideaki Otsuka"},{"name":"Takakazu Shinzato"},{"name":"Mitsunori Aramoto"},{"name":"武田 美雄"}]},"publication_date":"2007-10-10","publication_name":{"en":"Journal of Natural Medicines","ja":"Journal of Natural Medicines"},"volume":"Vol.61","number":"No.4","starting_page":"468","ending_page":"471","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s11418-007-0178-z"],"issn":["1340-3443"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10018519189/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1571698600299088128/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=157089","label":"url"}],"paper_title":{"en":"Chemical constituents of an Uzbek medicinal plant, Perovskia scrophularifolia","ja":"Chemical constituents of an Uzbek medicinal plant, Perovskia scrophularifolia"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Hayashi Takaaki"},{"name":"Masuda Toshiya"},{"name":"Honda Gisho"},{"name":"Takaishi Yoshihisa"},{"name":"Ito Michiho"},{"name":"Otsuka Hideaki"},{"name":"Matsunami Katsuyoshi"},{"name":"Khodzhimatov O.K."},{"name":"Ashurmetov O.A."}],"ja":[{"name":"武田 美雄"},{"name":"Hayashi Takaaki"},{"name":"増田 俊哉"},{"name":"Honda Gisho"},{"name":"高石 喜久"},{"name":"Ito Michiho"},{"name":"Otsuka Hideaki"},{"name":"Matsunami Katsuyoshi"},{"name":"Khodzhimatov O.K."},{"name":"Ashurmetov O.A."}]},"publication_date":"2007-01-10","publication_name":{"en":"Journal of Natural Medicines","ja":"Journal of Natural Medicines"},"volume":"Vol.61","number":"No.1","starting_page":"84","ending_page":"85","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s11418-006-0023-9"],"issn":["1340-3443"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10018519072/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1360574096051871232/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=157088","label":"url"}],"paper_title":{"en":"Tricalysiolide G and tricalysiols A and B:rearranged ent-kaurane-type and ent-kaurane-type diterpenoids from the leaves of Tricalysia dubia (Lindl.) Ohwi","ja":"Tricalysiolide G and tricalysiols A and B:rearranged ent-kaurane-type and ent-kaurane-type diterpenoids from the leaves of Tricalysia dubia (Lindl.) Ohwi"},"authors":{"en":[{"name":"He Dong-Hui"},{"name":"Matsunami Katsuyoshi"},{"name":"Otsuka Hideaki"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"Bando Masahiko"},{"name":"Takeda Yoshio"}],"ja":[{"name":"He Dong-Hui"},{"name":"Matsunami Katsuyoshi"},{"name":"Otsuka Hideaki"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"Bando Masahiko"},{"name":"武田 美雄"}]},"publication_date":"2007-01-10","publication_name":{"en":"Journal of Natural Medicines","ja":"Journal of Natural Medicines"},"volume":"Vol.61","number":"No.1","starting_page":"46","ending_page":"50","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1007/s11418-006-0016-8"],"issn":["1340-3443"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/10018439060/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001206409589632/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=193367","label":"url"}],"paper_title":{"en":"Identification of Antioxidative Compounds from Stevia","ja":"ステビア中の抗酸化性物質の同定"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Yamashita Daiki"},{"name":"Maekawa Tomomi"},{"name":"Sone Yoshiaki"},{"name":"Yamaguchi Hidemasa"},{"name":"Takeda Yoshio"},{"name":"Yamana Toshihiko"}],"ja":[{"name":"増田 俊哉"},{"name":"山下 泰輝"},{"name":"前川 智美"},{"name":"曽根 良昭"},{"name":"山口 英昌"},{"name":"武田 美雄"},{"name":"山名 俊彦"}]},"description":{"en":"Stevia (Stevia rebaudiana), a well-known sweet herb, has been reported to have potent antioxidant activity. Methanolic extract of Stevia was fractionated and subsequently purified according to the results of DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging assay, producing three active compounds. Structural analysis of these compounds revealed that they were 3,4-dicaffeolylquinic acid, 3,5-dicaffeolylquinic acid and quercetin-3-O-α-rhamnopyranoside. Their antioxidant activity was measured using a radical initiator AAPH 2,2'-azobis(2-amidinopropane)hydrochloride -induced lipid oxidation system. While their activity was not as high as that of trolox, the three isolated compounds exhibited potent antioxidant activity at a concentration of 60μmol/l.","ja":"ステビアの抗酸化成分を同定するに当たり,ステビアをメタノール抽出し,その抽出物の溶媒分画のうち,特異的にDPPHラジカル消去活性の強かった酢酸エチル可溶画分から,3種の活性成分を単離・同定した.この単離物質は,すべて,脂質の酸化に対して十分な抗酸化性を有することが判明した.ステビアの抗酸化性はこれまでカリウム等の無機塩によるものとされてきたが2),今回の有機フェノール成分もステビア抗酸化性に十分に寄与している可能性が考えられた."},"publication_date":"2006-12-15","publication_name":{"en":"Nippon Shokuhin Kagaku Kogaku Kaishi","ja":"日本食品科学工学会誌"},"volume":"Vol.53","number":"No.12","starting_page":"597","ending_page":"602","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.3136/nskkk.53.597"],"issn":["1341-027X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/16973192","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=157087","label":"url"}],"paper_title":{"en":"5-O-glucosyldihydrolavones from the leaves Helicia cochinchinensis","ja":"5-O-glucosyldihydrolavones from the leaves Helicia cochinchinensis"},"authors":{"en":[{"name":"Morimura Ken-ichi"},{"name":"Gatayama Asuka"},{"name":"Tsukimata Reiki"},{"name":"Matsunami Katsuyoshi"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Morimura Ken-ichi"},{"name":"Gatayama Asuka"},{"name":"Tsukimata Reiki"},{"name":"Matsunami Katsuyoshi"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"武田 美雄"}]},"description":{"en":"From the leaves of Helicia cochinchinensis, collected on Okinawa Island, seven phenolic glucosides and two terpenic glucosides were isolated. Five of the phenolic glucosides were previously known, being identified with p-coumaric and ferulic acids glucosyl esters, rhodioloside, helicidiol, and naringenin 5-O-beta-D-glucopyranoside. The structures of two other phenolic glucosides, named heliciosides A and B, were elucidated to be 5-O-beta-D-glucosides of 3-hydroxyflavanone, namely aromadendrin and taxifolin, by means of spectroscopic analyses. The two terpenic glucosides were identified with ampelopsisionoside and icariside C1.","ja":"From the leaves of Helicia cochinchinensis, collected on Okinawa Island, seven phenolic glucosides and two terpenic glucosides were isolated. Five of the phenolic glucosides were previously known, being identified with p-coumaric and ferulic acids glucosyl esters, rhodioloside, helicidiol, and naringenin 5-O-beta-D-glucopyranoside. The structures of two other phenolic glucosides, named heliciosides A and B, were elucidated to be 5-O-beta-D-glucosides of 3-hydroxyflavanone, namely aromadendrin and taxifolin, by means of spectroscopic analyses. The two terpenic glucosides were identified with ampelopsisionoside and icariside C1."},"publication_date":"2006-12","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.67","number":"No.24","starting_page":"2681","ending_page":"2685","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.phytochem.2006.08.001"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/17049570","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=157086","label":"url"}],"paper_title":{"en":"Bridelionosides A-F:Megastigmane glucosides from Bridelia glauca f. balansae","ja":"Bridelionosides A-F:Megastigmane glucosides from Bridelia glauca f. balansae"},"authors":{"en":[{"name":"Sueyoshi Etsuko"},{"name":"Liu Hui"},{"name":"Matsunami Katsuyoshi"},{"name":"Otsuka Hideaki"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Sueyoshi Etsuko"},{"name":"Liu Hui"},{"name":"Matsunami Katsuyoshi"},{"name":"Otsuka Hideaki"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"武田 美雄"}]},"description":{"en":"The chemical investigation of leaves of Bridelia glauca f. balansae afforded six megastigmane glucosides, named bridelionosides A-F, along with seven known megastigmane glucosides. Their structures were determined by a combination of spectroscopic analyses and by application of the modified Mosher's method.","ja":"The chemical investigation of leaves of Bridelia glauca f. balansae afforded six megastigmane glucosides, named bridelionosides A-F, along with seven known megastigmane glucosides. Their structures were determined by a combination of spectroscopic analyses and by application of the modified Mosher's method."},"publication_date":"2006-11","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.67","number":"No.22","starting_page":"2483","ending_page":"2493","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.phytochem.2006.09.007"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/17015977","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=157085","label":"url"}],"paper_title":{"en":"Radical-scavenging activities of new megastigmane glucosides from Macaranga tanarius (L.)Muelll.-Arg.","ja":"Radical-scavenging activities of new megastigmane glucosides from Macaranga tanarius (L.)Muelll.-Arg."},"authors":{"en":[{"name":"Matsunami Katsuyoshi"},{"name":"Takamori Ichiko"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"Kondo Kazunari"},{"name":"Otsuka Hideaki"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Matsunami Katsuyoshi"},{"name":"Takamori Ichiko"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"Kondo Kazunari"},{"name":"Otsuka Hideaki"},{"name":"武田 美雄"}]},"description":{"en":"Four new megastigmane glucosides, named macarangiosides A-D (2-5), together with mallophenol B, lauroside E, methyl brevifolin carboxylate, and hyperin and isoquercitrin as a mixture were isolated from the leaves of Macaranga tanarius (L.) MULL.-ARG. (Euphorbiaceae). Their structures were elucidated by spectroscopic and chemical analyses. Macarangioside A-C (2-4) and mallophenol B were galloylated on glucose moiety and possessed the potent 2,2-diphenyl-picrylhydrazyl (DPPH) radical-scavenging activity.","ja":"Four new megastigmane glucosides, named macarangiosides A-D (2-5), together with mallophenol B, lauroside E, methyl brevifolin carboxylate, and hyperin and isoquercitrin as a mixture were isolated from the leaves of Macaranga tanarius (L.) MULL.-ARG. (Euphorbiaceae). Their structures were elucidated by spectroscopic and chemical analyses. Macarangioside A-C (2-4) and mallophenol B were galloylated on glucose moiety and possessed the potent 2,2-diphenyl-picrylhydrazyl (DPPH) radical-scavenging activity."},"publication_date":"2006-10","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.54","number":"No.10","starting_page":"1403","ending_page":"1407","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.54.1403"],"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=157084","label":"url"}],"paper_title":{"en":"Trypanocidal constituents of Dracocephalum komarovi","ja":"Trypanocidal constituents of Dracocephalum komarovi"},"authors":{"en":[{"name":"Utiyama Nahoko"},{"name":"Kiuchi Fumiyuki"},{"name":"Ito Michiho"},{"name":"Honda Gisho"},{"name":"Takeda Yoshio"},{"name":"Khodzhimatov O.K."},{"name":"Ashurmetov O.A."}],"ja":[{"name":"Utiyama Nahoko"},{"name":"Kiuchi Fumiyuki"},{"name":"Ito Michiho"},{"name":"Honda Gisho"},{"name":"武田 美雄"},{"name":"Khodzhimatov O.K."},{"name":"Ashurmetov O.A."}]},"publication_date":"2006-05-01","publication_name":{"en":"Tetrahedron","ja":"Tetrahedron"},"volume":"Vol.62","number":"No.18","starting_page":"4355","ending_page":"4359","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.tet.2006.02.067"],"issn":["0040-4020"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1016/j.tet.2005.11.024","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1570009751563873280/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=133185","label":"url"}],"paper_title":{"en":"Tricalysiolides A-F new rearranged ent-kaurane diterpenes from Tricalysia dubia","ja":"Tricalysiolides A-F new rearranged ent-kaurane diterpenes from Tricalysia dubia"},"authors":{"en":[{"name":"Murakami Koichi"},{"name":"Hitotsuyanagi Yukio"},{"name":"Sugeta Noriko"},{"name":"Sakakura Kei-ichi"},{"name":"Fujita Kazuya"},{"name":"Haruhiko Fukaya"},{"name":"Aoyagi Yutaka"},{"name":"Hasuda Tomoyo"},{"name":"Kinoshita Takeshi"},{"name":"He Dong-Hui"},{"name":"Otsuka Hideaki"},{"name":"Takeda Yoshio"},{"name":"Takeya Koichi"}],"ja":[{"name":"Murakami Koichi"},{"name":"Hitotsuyanagi Yukio"},{"name":"Sugeta Noriko"},{"name":"Sakakura Kei-ichi"},{"name":"Fujita Kazuya"},{"name":"Haruhiko Fukaya"},{"name":"Aoyagi Yutaka"},{"name":"Hasuda Tomoyo"},{"name":"Kinoshita Takeshi"},{"name":"He Dong-Hui"},{"name":"Otsuka Hideaki"},{"name":"武田 美雄"},{"name":"Takeya Koichi"}]},"publication_date":"2006-02","publication_name":{"en":"Tetrahedron","ja":"Tetrahedron"},"volume":"Vol.62","number":"No.7","starting_page":"1512","ending_page":"1519","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.tet.2005.11.024"],"issn":["0040-4020"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/16271376","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1572824501331987200/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=133181","label":"url"}],"paper_title":{"en":"Tricalysiosides H-O:Ent-kaurane glucosides from the leaves of Tricalysia dubia","ja":"Tricalysiosides H-O:Ent-kaurane glucosides from the leaves of Tricalysia dubia"},"authors":{"en":[{"name":"He Dong-Hui"},{"name":"Matsunami Katsuyoshi"},{"name":"Otsuka Hideaki"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"Bando Masahiko"},{"name":"Takeda Yoshio"}],"ja":[{"name":"He Dong-Hui"},{"name":"松浪 勝義"},{"name":"大塚 英昭"},{"name":"新里 孝和"},{"name":"新本 光孝"},{"name":"坂東 政彦"},{"name":"武田 美雄"}]},"description":{"en":"Eight ent-kaurane glucosides, named tricalysiosides H-O, were isolated from Tricalysia dubia. Tricalysioside H possessed a hydroxyl group at the 1-position, to which the glucose moiety was attached. The structure was first elucidated by means of spectroscopic data analysis and finally confirmed by X-ray crystallography. Since acid hydrolysis of 1 gave D-glucose, the aglycone was proved to have an enantio-kaurane type skeleton. The structures of tricalysiosides I-O were mainly elucidated from analysis of spectroscopic evidence.","ja":"Eight ent-kaurane glucosides, named tricalysiosides H-O, were isolated from Tricalysia dubia. Tricalysioside H possessed a hydroxyl group at the 1-position, to which the glucose moiety was attached. The structure was first elucidated by means of spectroscopic data analysis and finally confirmed by X-ray crystallography. Since acid hydrolysis of 1 gave D-glucose, the aglycone was proved to have an enantio-kaurane type skeleton. The structures of tricalysiosides I-O were mainly elucidated from analysis of spectroscopic evidence."},"publication_date":"2005-12","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.66","number":"No.24","starting_page":"2857","ending_page":"2864","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.phytochem.2005.09.014"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/16104807","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-24344497764&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=130873","label":"url"}],"paper_title":{"en":"Recovery of Antioxidant Activity from Carnosol Quinone: Antioxidants Obtained from a Water-Promoted Conversion of Carnosol Quinone","ja":"Recovery of Antioxidant Activity from Carnosol Quinone: Antioxidants Obtained from a Water-Promoted Conversion of Carnosol Quinone"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Kirikihira Takuya"},{"name":"Takeda Yoshio"}],"ja":[{"name":"増田 俊哉"},{"name":"Kirikihira Takuya"},{"name":"武田 美雄"}]},"description":{"en":"Carnosol is one of the main antioxidants in sage and rosemary. Although carnosol quinone is the antioxidation product of carnosol and has a very weak antioxidant activity, its treatment in water-containing solvent restored its strong antioxidant activity. HPLC analysis of the water-stimulated recovery reaction of the antioxidant activity revealed that the strong activity was due to the reproduced carnosol. The analysis also showed that an almost equal amount of quinone derivatives of rosmanol (rosmanol quinone) was produced in the reaction along with the carnosol. The rosmanol was formed by the addition of 1 equiv of water and the following isomerization from carnosol quinone in the water-containing solvent. The formed rosmanol was also found to be oxidized by the remaining carnosol quinone to produce rosmanol quinone. At the same time, carnosol quinone was reduced to afford carnosol. This redox phenomenon is an important part of the mechanism for the recovery of the antioxidant activity from carnosol quinone under the water-containing conditions.","ja":"Carnosol is one of the main antioxidants in sage and rosemary. Although carnosol quinone is the antioxidation product of carnosol and has a very weak antioxidant activity, its treatment in water-containing solvent restored its strong antioxidant activity. HPLC analysis of the water-stimulated recovery reaction of the antioxidant activity revealed that the strong activity was due to the reproduced carnosol. The analysis also showed that an almost equal amount of quinone derivatives of rosmanol (rosmanol quinone) was produced in the reaction along with the carnosol. The rosmanol was formed by the addition of 1 equiv of water and the following isomerization from carnosol quinone in the water-containing solvent. The formed rosmanol was also found to be oxidized by the remaining carnosol quinone to produce rosmanol quinone. At the same time, carnosol quinone was reduced to afford carnosol. This redox phenomenon is an important part of the mechanism for the recovery of the antioxidant activity from carnosol quinone under the water-containing conditions."},"publication_date":"2005-08-24","publication_name":{"en":"Journal of Agricultural and Food Chemistry","ja":"Journal of Agricultural and Food Chemistry"},"volume":"Vol.53","number":"No.17","starting_page":"6831","ending_page":"6834","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/jf050685s"],"issn":["0021-8561"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://cpb.pharm.or.jp/abst/200507/ac53070800.html","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/15997139","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124817","label":"url"}],"paper_title":{"en":"Staphylionosides A-K: Megastigmane Glucosides from the Leaves of Staphylea bumalda DC.","ja":"Staphylionosides A-K: Megastigmane Glucosides from the Leaves of Staphylea bumalda DC."},"authors":{"en":[{"name":"Yu Qian"},{"name":"Matsunami Katsuyoshi"},{"name":"Otsuka Hideaki"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Yu Qian"},{"name":"Matsunami Katsuyoshi"},{"name":"大塚 英昭"},{"name":"武田 美雄"}]},"description":{"en":"Chemical investigation of leaves of Staphylea bumalda DC., collected in the suburbs of Hiroshima City, afforded 11 new megastigmane glucosides, named staphylionosides A-K (3-13), along with two known megastigmane glucosides (1, 2). The relative structures were elucidated from spectroscopic evidence, and the absolute structures of the aglycones were determined by means of the combination of beta-D-glucosylation-induced shift-trends and the modified Mosher's method.","ja":"Chemical investigation of leaves of Staphylea bumalda DC., collected in the suburbs of Hiroshima City, afforded 11 new megastigmane glucosides, named staphylionosides A-K (3-13), along with two known megastigmane glucosides (1, 2). The relative structures were elucidated from spectroscopic evidence, and the absolute structures of the aglycones were determined by means of the combination of beta-D-glucosylation-induced shift-trends and the modified Mosher's method."},"publication_date":"2005-07","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.53","number":"No.7","starting_page":"800","ending_page":"807","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.53.800"],"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/15771898","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=119877","label":"url"}],"paper_title":{"en":"Lanceocrepidiasides A-F, glucosides of guaiane-type sesquiterpene from Crepidiastrum lanceolatum","ja":"Lanceocrepidiasides A-F, glucosides of guaiane-type sesquiterpene from Crepidiastrum lanceolatum"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Masuda Toshiya"},{"name":"Morikawa Hiroyuki"},{"name":"Ayabe Hisako"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"Otsuka Hideaki"}],"ja":[{"name":"武田 美雄"},{"name":"増田 俊哉"},{"name":"森川 浩之"},{"name":"綾部 久子"},{"name":"平田 永二"},{"name":"新里 孝和"},{"name":"新本 光孝"},{"name":"大塚 英昭"}]},"description":{"en":"沖縄で民間薬,食用として用いられているホソバワダン地上部より6種の新グアイアン型セスキテルペン配糖体6種を8種の既知化合物と共に単離し,その化学構造を明らかにした.","ja":"沖縄で民間薬,食用として用いられているホソバワダン地上部より6種の新グアイアン型セスキテルペン配糖体6種を8種の既知化合物と共に単離し,その化学構造を明らかにした."},"publication_date":"2005-03","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.66","number":"No.6","starting_page":"727","ending_page":"732","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.phytochem.2005.01.004"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/110008732356/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520853833571258240/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-14944348599&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124818","label":"url"}],"paper_title":{"en":"Indole alkaloids from Rheum maximowiczii","ja":"Indole alkaloids from Rheum maximowiczii"},"authors":{"en":[{"name":"Komakine Nozomi"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Komakine Nozomi"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"A new indol alkaloid along with 17 known compounds were isolated from the seeds of Rheum maximowiczii Losinsk (Polygonaceae). Its structure was elucidated from the 2D NMR and other spectral evidence. Several of these compounds were screened for cytokine-inducing activity on human peripheral blood mononuclear cells. The cytokine-inducing activity of some of the isolated compounds is also reported.","ja":"A new indol alkaloid along with 17 known compounds were isolated from the seeds of Rheum maximowiczii Losinsk (Polygonaceae). Its structure was elucidated from the 2D NMR and other spectral evidence. Several of these compounds were screened for cytokine-inducing activity on human peripheral blood mononuclear cells. The cytokine-inducing activity of some of the isolated compounds is also reported."},"publication_date":"2005-02-20","publication_name":{"en":"Natural Medicines","ja":"Natural Medicines"},"volume":"Vol.59","number":"No.1","starting_page":"45","ending_page":"48","languages":["eng"],"referee":true,"identifiers":{"issn":["1340-3443"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/15665485","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-15244355251&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=115890","label":"url"}],"paper_title":{"en":"Screening for Tyrosinase Inhibitors among Extracts of Seashore Plants and Identification of Potent Inhibitors from Garcinia subelliptica","ja":"Screening for Tyrosinase Inhibitors among Extracts of Seashore Plants and Identification of Potent Inhibitors from Garcinia subelliptica"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Yamashita Daiki"},{"name":"Takeda Yoshio"},{"name":"Yonemori Shigetomo"}],"ja":[{"name":"増田 俊哉"},{"name":"Yamashita Daiki"},{"name":"武田 美雄"},{"name":"Yonemori Shigetomo"}]},"description":{"en":"The tyrosinase inhibitory activity of methanol extracts of the leaves of 39 plant species growing on the seashore of Iriomote island (Okinawa, Japan) was investigated. The extracts of Hibiscus tiliaceus, Carex pumila, and Garcinia subelliptica showed potent activity among them. The inhibitors in the extract of Garcinia subelliptica were purified by assay-guided fractionation to give two biflavonoids. These were known compounds (2R,3S-5,7,4',5'',7'',3''',4'''-heptahydroxy flavanone[3-8''] flavone and 5,7,4',5'',7'',3''',4'''-heptahydroxy[3-8''] biflavanone), although their strong inhibitory activity toward tyrosinase is revealed for the first time in this work. One of these biflavonoids (2R,3S-5,7,4',5'',7'',3''',4'''-heptahydroxy flavanone[3-8''] flavone) showed much stronger activity (IC50 2.5 microM) than that of kojic acid (IC50 9.1 microM) when L-tyrosine was used as the substrate.","ja":"The tyrosinase inhibitory activity of methanol extracts of the leaves of 39 plant species growing on the seashore of Iriomote island (Okinawa, Japan) was investigated. The extracts of Hibiscus tiliaceus, Carex pumila, and Garcinia subelliptica showed potent activity among them. The inhibitors in the extract of Garcinia subelliptica were purified by assay-guided fractionation to give two biflavonoids. These were known compounds (2R,3S-5,7,4',5'',7'',3''',4'''-heptahydroxy flavanone[3-8''] flavone and 5,7,4',5'',7'',3''',4'''-heptahydroxy[3-8''] biflavanone), although their strong inhibitory activity toward tyrosinase is revealed for the first time in this work. One of these biflavonoids (2R,3S-5,7,4',5'',7'',3''',4'''-heptahydroxy flavanone[3-8''] flavone) showed much stronger activity (IC50 2.5 microM) than that of kojic acid (IC50 9.1 microM) when L-tyrosine was used as the substrate."},"publication_date":"2005-01","publication_name":{"en":"Bioscience, Biotechnology, and Biochemistry","ja":"Bioscience, Biotechnology, and Biochemistry"},"volume":"Vol.69","number":"No.1","starting_page":"197","ending_page":"201","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1271/bbb.69.197"],"issn":["0916-8451"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1021/np040024+","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/15568778","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=127096","label":"url"}],"paper_title":{"en":"Prenylated Benzophenones and Xanthones from Hypericum scabrum","ja":"Prenylated Benzophenones and Xanthones from Hypericum scabrum"},"authors":{"en":[{"name":"Tanaka Naonobu"},{"name":"Takaishi Yoshihisa"},{"name":"Shikishima Yasuhiro"},{"name":"Nakanishi Yuka"},{"name":"Bastow Kenneth"},{"name":"Lee Kuo-Hsiung"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"田中 直伸"},{"name":"高石 喜久"},{"name":"Shikishima Yasuhiro"},{"name":"Nakanishi Yuka"},{"name":"Bastow Kenneth"},{"name":"Lee Kuo-Hsiung"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"Two new polyprenylated benzophenones, a new polyprenylated phloroglucinol, and six new xanthone derivatives were isolated from the aerial parts of the Uzbekistan medicinal plant Hypericum scabrum. Their structures were elucidated on the basis of spectroscopic evidence. The isolated compounds showed moderate cytotoxicity for human tumor cells.","ja":"Two new polyprenylated benzophenones, a new polyprenylated phloroglucinol, and six new xanthone derivatives were isolated from the aerial parts of the Uzbekistan medicinal plant Hypericum scabrum. Their structures were elucidated on the basis of spectroscopic evidence. The isolated compounds showed moderate cytotoxicity for human tumor cells."},"publication_date":"2004-11","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.67","number":"No.11","starting_page":"1870","ending_page":"1875","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np040024+"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/15340194","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=100042","label":"url"}],"paper_title":{"en":"Terpenic and phenolic glycosides from leaves of Breynia officinalis HEMSL","ja":"Terpenic and phenolic glycosides from leaves of Breynia officinalis HEMSL"},"authors":{"en":[{"name":"Morikawa Hiroyuki"},{"name":"Kasai Ryoji"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Morikawa Hiroyuki"},{"name":"Kasai Ryoji"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsunori"},{"name":"武田 美雄"}]},"description":{"en":"沖縄産トウダイグサ科植物オオシマコバンノキ葉部の配糖体成分を検索した結果,4種の新テルペン配糖体,breyniaionosideA-Dと共に3種のフェノール性新配糖体を単離し,その化学構造を明らかにした.","ja":"沖縄産トウダイグサ科植物オオシマコバンノキ葉部の配糖体成分を検索した結果,4種の新テルペン配糖体,breyniaionosideA-Dと共に3種のフェノール性新配糖体を単離し,その化学構造を明らかにした."},"publication_date":"2004-09","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.52","number":"No.9","starting_page":"1086","ending_page":"1090","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.52.1086"],"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-4043146489&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=89167","label":"url"}],"paper_title":{"en":"Thermal recovery of antioxidant activity from carnosol quinone, the main antioxidation product of carnosol","ja":"Thermal recovery of antioxidant activity from carnosol quinone, the main antioxidation product of carnosol"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Kirikihira Takuya"},{"name":"Takeda Yoshio"},{"name":"Yonemori Shigetomo"}],"ja":[{"name":"増田 俊哉"},{"name":"Kirikihira Takuya"},{"name":"武田 美雄"},{"name":"Yonemori Shigetomo"}]},"publication_date":"2004-08","publication_name":{"en":"Journal of the Science of Food and Agriculture","ja":"Journal of the Science of Food and Agriculture"},"volume":"Vol.84","number":"No.11","starting_page":"1421","ending_page":"1427","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1002/jsfa.1836"],"issn":["1097-0010"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1016/j.jep.2004.02.016","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/15138001","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124819","label":"url"}],"paper_title":{"en":"Folk medicine in Uzbekistan: I. Toshkent, Djizzax, and Samarqand provinces","ja":"Folk medicine in Uzbekistan: I. Toshkent, Djizzax, and Samarqand provinces"},"authors":{"en":[{"name":"Ekrem Sezik"},{"name":"Yesilada Erdem"},{"name":"Shadidoyatov Hüsnitdin"},{"name":"Kulivey Zeynullah"},{"name":"Nigmatullaev M. Alim"},{"name":"Hamdulla N. Aripov"},{"name":"Takaishi Yoshihisa"},{"name":"Takeda Yoshio"},{"name":"Honda Gisho"}],"ja":[{"name":"Ekrem Sezik"},{"name":"Yesilada Erdem"},{"name":"Shadidoyatov Hüsnitdin"},{"name":"Kulivey Zeynullah"},{"name":"Nigmatullaev M. Alim"},{"name":"Hamdulla N. Aripov"},{"name":"高石 喜久"},{"name":"武田 美雄"},{"name":"Honda Gisho"}]},"description":{"en":"Uzbekistan is one of the Turcic republics in Central Asia where a desert continental climate mainly prevails in territories. Nevertheless, this expedition was carried out in the northeast and east higher lands, where flora is richer. The interviews were performed in seven villages of Toshkent and in neighboring provinces of Samarqand, Djizzax and at Urgut Bazaar of Samarqand. Altogether 177 folk remedies were recorded in the surveyed area. Among these folk remedies, 162 remedies were obtained from 79 different kinds of plant species that belong to 31 different families, whereas, 15 animal originated remedies that belong to 8 different animals are listed, which includes their vernacular and scientific names, indications and recipes for preparations.","ja":"Uzbekistan is one of the Turcic republics in Central Asia where a desert continental climate mainly prevails in territories. Nevertheless, this expedition was carried out in the northeast and east higher lands, where flora is richer. The interviews were performed in seven villages of Toshkent and in neighboring provinces of Samarqand, Djizzax and at Urgut Bazaar of Samarqand. Altogether 177 folk remedies were recorded in the surveyed area. Among these folk remedies, 162 remedies were obtained from 79 different kinds of plant species that belong to 31 different families, whereas, 15 animal originated remedies that belong to 8 different animals are listed, which includes their vernacular and scientific names, indications and recipes for preparations."},"publication_date":"2004-06","publication_name":{"en":"Journal of Ethnopharmacology","ja":"Journal of Ethnopharmacology"},"volume":"Vol.92","number":"No.2-3","starting_page":"197","ending_page":"207","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.jep.2004.02.016"],"issn":["0378-8741"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/15133212","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=85234","label":"url"}],"paper_title":{"en":"Glochidiolide, isoglochidiolide, acuminaminoside, and glochidacuminosides A-D from the leaves of Glochidion acuminatum MUELL.","ja":"Glochidiolide, isoglochidiolide, acuminaminoside, and glochidacuminosides A-D from the leaves of Glochidion acuminatum MUELL."},"authors":{"en":[{"name":"Otsuka Hideaki"},{"name":"Takeda Yoshio"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Bando Masahiko"}],"ja":[{"name":"大塚 英昭"},{"name":"武田 美雄"},{"name":"平田 永二"},{"name":"新里 孝和"},{"name":"坂東 政彦"}]},"description":{"en":"沖縄産トウダイグサ科植物ウラジロカンコノキ葉部の成分研究を行い,新規のbutenolide二量体2種,含窒素C-8二量体acuminaminoside,C-8化合物の配糖体4種を単離し,その化学構造をX線結晶解析を含む手法により明らかにした.","ja":"沖縄産トウダイグサ科植物ウラジロカンコノキ葉部の成分研究を行い,新規のbutenolide二量体2種,含窒素C-8二量体acuminaminoside,C-8化合物の配糖体4種を単離し,その化学構造をX線結晶解析を含む手法により明らかにした."},"publication_date":"2004-05","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.52","number":"No.5","starting_page":"591","ending_page":"596","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.52.591"],"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/14759546","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=85220","label":"url"}],"paper_title":{"en":"Lasianthionosides A-C, megastigmane glucosides from leaves of Lasianthus fordii","ja":"Lasianthionosides A-C, megastigmane glucosides from leaves of Lasianthus fordii"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Shimizu Hideko"},{"name":"Masuda Toshiya"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Bando Masahiko"},{"name":"Otsuka Hideaki"}],"ja":[{"name":"武田 美雄"},{"name":"清水 秀子"},{"name":"増田 俊哉"},{"name":"平田 永二"},{"name":"新里 孝和"},{"name":"坂東 政彦"},{"name":"大塚 英昭"}]},"description":{"en":"沖縄産アカネ科植物タシロルリミノキ葉部の配糖体成分を検索し,4種の既知化合物と共に3種の新メガスチグマン配糖体lasianthionosides A,B,Cを単離し,その化学構造をX線結晶解析を含む手法により明らかにした.","ja":"沖縄産アカネ科植物タシロルリミノキ葉部の配糖体成分を検索し,4種の既知化合物と共に3種の新メガスチグマン配糖体lasianthionosides A,B,Cを単離し,その化学構造をX線結晶解析を含む手法により明らかにした."},"publication_date":"2004-02","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.65","number":"No.4","starting_page":"485","ending_page":"489","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.phytochem.2003.08.025"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/14759542","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0842306098&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=85208","label":"url"}],"paper_title":{"en":"C,O-diglycosylapigenin from the leaves of Rhamnella inaequilata","ja":"C,O-diglycosylapigenin from the leaves of Rhamnella inaequilata"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Okada Yoshihiro"},{"name":"Masuda Toshiya"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Otsuka Hideaki"}],"ja":[{"name":"武田 美雄"},{"name":"岡田 吉祐"},{"name":"増田 俊哉"},{"name":"平田 永二"},{"name":"新里 孝和"},{"name":"大塚 英昭"}]},"description":{"en":"沖縄産ヤエヤマネコノチチ葉部の配糖体成分を検索し,2種の既知フラボンC- ジグりコシドと共にrhamnellaflavosides A,B,Cと命名したC,O- ジグリコシルフラボンを単離し,その化学構造をスペクトル解析および化学反応の結果より明らかにした.","ja":"沖縄産ヤエヤマネコノチチ葉部の配糖体成分を検索し,2種の既知フラボンC- ジグりコシドと共にrhamnellaflavosides A,B,Cと命名したC,O- ジグリコシルフラボンを単離し,その化学構造をスペクトル解析および化学反応の結果より明らかにした."},"publication_date":"2004-02","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.65","number":"No.4","starting_page":"463","ending_page":"468","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.phytochem.2003.12.005"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://cat.inist.fr/?aModele=afficheN&cpsidt=15346027","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1574231876485651328/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=85227","label":"url"}],"paper_title":{"en":"A trypanocidal diterpene with novel skeleton from Dracocephalum komarovi","ja":"A trypanocidal diterpene with novel skeleton from Dracocephalum komarovi"},"authors":{"en":[{"name":"Uchiyama Naoko"},{"name":"Ito Michiho"},{"name":"Kiuchi Fumiyuki"},{"name":"Honda Gisho"},{"name":"Takeda Yoshio"},{"name":"Khodzhimatov K Olimjon"},{"name":"Ashurmetov A Ozodbek"}],"ja":[{"name":"Uchiyama Naoko"},{"name":"伊藤 美千穂"},{"name":"木内 文之"},{"name":"本多 義昭"},{"name":"武田 美雄"},{"name":"Khodzhimatov K Olimjon"},{"name":"Ashurmetov A Ozodbek"}]},"description":{"en":"ウズベキスタン産薬用植物Dracocephalum komarovi全草から特異な spiro-octahydroindene骨格を持つ新ジテルペンkomarovispironeを単離し,その化学構造を明らかにした.","ja":"ウズベキスタン産薬用植物Dracocephalum komarovi全草から特異な spiro-octahydroindene骨格を持つ新ジテルペンkomarovispironeを単離し,その化学構造を明らかにした."},"publication_date":"2004-01-12","publication_name":{"en":"Tetrahedron Letters","ja":"Tetrahedron Letters"},"volume":"Vol.45","number":"No.3","starting_page":"531","ending_page":"533","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/j.tetlet.2003.10.202"],"issn":["0040-4039"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/110008732252/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520572357193355008/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0037787823&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124820","label":"url"}],"paper_title":{"en":"Sesquiterpenoids from Artemisia tenuisecta","ja":"Sesquiterpenoids from Artemisia tenuisecta"},"authors":{"en":[{"name":"Kawazoe Kazuyoshi"},{"name":"Morishita Nao"},{"name":"Asako Nagao"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Ito Mrchiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"川添 和義"},{"name":"Morishita Nao"},{"name":"Asako Nagao"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Ito Mrchiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"From the aerial part of Artemisia tenuisecta Nevski (Asteraceae) a new sesquiterpene along with 16 known sesquiterpenoides were isolated. Its relative structure was elucidated as 1α-acetoxyeudesm- 4,5-expoxy-6β,11βH-12,6-olide from the 2D NMR and other spectral evidence.","ja":"From the aerial part of Artemisia tenuisecta Nevski (Asteraceae) a new sesquiterpene along with 16 known sesquiterpenoides were isolated. Its relative structure was elucidated as 1α-acetoxyeudesm- 4,5-expoxy-6β,11βH-12,6-olide from the 2D NMR and other spectral evidence."},"publication_date":"2003-06-20","publication_name":{"en":"Natural Medicines","ja":"Natural Medicines"},"volume":"Vol.57","number":"No.3","starting_page":"114","ending_page":"116","languages":["eng"],"referee":true,"identifiers":{"issn":["1340-3443"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12843672","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=76002","label":"url"}],"paper_title":{"en":"Cytotoxic Screening of Medicinal and Edible Plants in Okinawa, Japan, and Identification of the Main Toxic Constituent of Rhodea japonica (Omoto)","ja":"Cytotoxic Screening of Medicinal and Edible Plants in Okinawa, Japan, and Identification of the Main Toxic Constituent of Rhodea japonica (Omoto)"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Oyama Yasuo"},{"name":"Ymamamoto Natsuko"},{"name":"Umebayashi Chisato"},{"name":"Nakao Hiromi"},{"name":"Toi Yukiko"},{"name":"Takeda Yoshio"},{"name":"Nakamoto Katsuo"},{"name":"Kuninaga Hideki"},{"name":"NIshizato Yukari"},{"name":"Nonaka Akira"}],"ja":[{"name":"増田 俊哉"},{"name":"小山 保夫"},{"name":"Ymamamoto Natsuko"},{"name":"Umebayashi Chisato"},{"name":"Nakao Hiromi"},{"name":"Toi Yukiko"},{"name":"武田 美雄"},{"name":"Nakamoto Katsuo"},{"name":"Kuninaga Hideki"},{"name":"NIshizato Yukari"},{"name":"Nonaka Akira"}]},"description":{"en":"The cytotoxic activity of ethanol extracts from 53 parts of 36 species of medicinal and edible plants cultivated in Okinawa was measured by using K562 human leukemia cells by a flow cytometric method. Two extracts from Rhodea japonica and Hypericum chinense were cytotoxic at a concentration of 10 microg/ml. The main cytotoxic constituent of Rhodea japonica was isolated and identified to be rhodexin A, which has been isolated as a cardetonic agent of the plant. The IC(50) value for rhodexin A against the growth of K562 cells was 19 nM, this activity being much stronger than that of ouabain (IC(50), 60 nM).","ja":"The cytotoxic activity of ethanol extracts from 53 parts of 36 species of medicinal and edible plants cultivated in Okinawa was measured by using K562 human leukemia cells by a flow cytometric method. Two extracts from Rhodea japonica and Hypericum chinense were cytotoxic at a concentration of 10 microg/ml. The main cytotoxic constituent of Rhodea japonica was isolated and identified to be rhodexin A, which has been isolated as a cardetonic agent of the plant. The IC(50) value for rhodexin A against the growth of K562 cells was 19 nM, this activity being much stronger than that of ouabain (IC(50), 60 nM)."},"publication_date":"2003-06","publication_name":{"en":"Bioscience, Biotechnology, and Biochemistry","ja":"Bioscience, Biotechnology, and Biochemistry"},"volume":"Vol.67","number":"No.6","starting_page":"1401","ending_page":"1404","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1271/bbb.67.1401"],"issn":["0916-8451"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12643638","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=76003","label":"url"}],"paper_title":{"en":"A Simple Detection Method of Powerful Antiradical Compounds in the Raw Extract of Plants and Its Application for the Identification of Antiraducal Plant Constituents","ja":"A Simple Detection Method of Powerful Antiradical Compounds in the Raw Extract of Plants and Its Application for the Identification of Antiraducal Plant Constituents"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Inaba Yuzuru"},{"name":"Maekawa Tomomi"},{"name":"Takeda Yoshio"},{"name":"Yamaguchi Hidemasa"},{"name":"Nakamoto Katsuo"},{"name":"KUninaga Hideki"},{"name":"NIshizato Saori"},{"name":"Nonaka Akira"}],"ja":[{"name":"増田 俊哉"},{"name":"Inaba Yuzuru"},{"name":"Maekawa Tomomi"},{"name":"武田 美雄"},{"name":"Yamaguchi Hidemasa"},{"name":"Nakamoto Katsuo"},{"name":"KUninaga Hideki"},{"name":"NIshizato Saori"},{"name":"Nonaka Akira"}]},"description":{"en":"A simple detection method for a powerful radical scavenging compound in a mixture containing a large variety of compounds, such as the raw extract of edible plants, was developed using 1,1-diphenyl-2-picrylhydrazyl (DPPH) as the radical reagent. The method was established on the basis of the features of the typical chain-breaking antioxidation reaction mechanism, which suggests that the radical scavenging antioxidant should be converted to other stable nonradical compounds during the reaction. This method requires only a simple HPLC instrument, and the disappearance or decrease in the peak intensity, which is induced by the addition of DPPH. This change is monitored by the HPLC to detect the powerful radical scavenger from the complex mixture. The method was applied to the detection and identification of the most powerful antiradical compound in the extracts of three antioxidatively active plant extracts (Psidium guajava, Citrus depressa, and Hypericum chinense). The radical scavenging efficiency of a newly identified compound from H. chinense was also compared with that of Trolox and catechin using the method.","ja":"A simple detection method for a powerful radical scavenging compound in a mixture containing a large variety of compounds, such as the raw extract of edible plants, was developed using 1,1-diphenyl-2-picrylhydrazyl (DPPH) as the radical reagent. The method was established on the basis of the features of the typical chain-breaking antioxidation reaction mechanism, which suggests that the radical scavenging antioxidant should be converted to other stable nonradical compounds during the reaction. This method requires only a simple HPLC instrument, and the disappearance or decrease in the peak intensity, which is induced by the addition of DPPH. This change is monitored by the HPLC to detect the powerful radical scavenger from the complex mixture. The method was applied to the detection and identification of the most powerful antiradical compound in the extracts of three antioxidatively active plant extracts (Psidium guajava, Citrus depressa, and Hypericum chinense). The radical scavenging efficiency of a newly identified compound from H. chinense was also compared with that of Trolox and catechin using the method."},"publication_date":"2003-04","publication_name":{"en":"Journal of Agricultural and Food Chemistry","ja":"Journal of Agricultural and Food Chemistry"},"volume":"Vol.51","number":"No.7","starting_page":"1831","ending_page":"1838","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/jf026112m"],"issn":["0021-8561"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://cat.inist.fr/?aModele=afficheN&cpsidt=14616711","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12648547","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75506","label":"url"}],"paper_title":{"en":"Muscanone:a 3-O-(1\",8\",14\"-trimenyl)naringenin from Commiphora","ja":"Muscanone:a 3-O-(1\",8\",14\"-trimenyl)naringenin from Commiphora"},"authors":{"en":[{"name":"Fatope Oladeji Majekodunmi"},{"name":"Al-Burtomani S Suad Khamis"},{"name":"Ochei O John"},{"name":"Abdulnour O Abdulrahman"},{"name":"Al-Kindy Salma M Z"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Fatope Oladeji Majekodunmi"},{"name":"Al-Burtomani S Suad Khamis"},{"name":"Ochei O John"},{"name":"Abdulnour O Abdulrahman"},{"name":"Al-Kindy Salma M Z"},{"name":"武田 美雄"}]},"description":{"en":"オマーン産Commiphora wightii枝部より抗カビ活性を有する新naringeninny誘導体,musucanoneを単離し,その化学構造を明らかにした.","ja":"オマーン産Commiphora wightii枝部より抗カビ活性を有する新naringeninny誘導体,musucanoneを単離し,その化学構造を明らかにした."},"publication_date":"2003-04","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.62","number":"No.8","starting_page":"1251","ending_page":"1255","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(02)00686-6"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12612412","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75504","label":"url"}],"paper_title":{"en":"GlochidionosidesA-D:megastigmane glucosides from leaves of Glochidion Zeylanicum (Gaertn.)A. Juss.","ja":"GlochidionosidesA-D:megastigmane glucosides from leaves of Glochidion Zeylanicum (Gaertn.)A. Juss."},"authors":{"en":[{"name":"Otsuka Hideaki"},{"name":"Kijima Hidehiko"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Takushi Anki"},{"name":"Masahiko Bando"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Otsuka Hideaki"},{"name":"Kijima Hidehiko"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Takushi Anki"},{"name":"Masahiko Bando"},{"name":"武田 美雄"}]},"description":{"en":"沖縄産トウダイグサ科植物葉部の配糖体を検索した結果単離することができたメガスチグマン配糖体glochidionionosides A-Dの化学構造を明らかにした.","ja":"沖縄産トウダイグサ科植物葉部の配糖体を検索した結果単離することができたメガスチグマン配糖体glochidionionosides A-Dの化学構造を明らかにした."},"publication_date":"2003-03","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.51","number":"No.3","starting_page":"286","ending_page":"290","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.51.286"],"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12620329","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1571698601680393088/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75500","label":"url"}],"paper_title":{"en":"Stereochemistry of megastigmane glucosides from Glochidion zeylanicum and Alangium premnifolium","ja":"Stereochemistry of megastigmane glucosides from Glochidion zeylanicum and Alangium premnifolium"},"authors":{"en":[{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"武田 美雄"}]},"description":{"en":"沖縄産カキバカンコノキおよびシマウリノキから単離されたメガスチグマン配糖体のうち,その一部の絶対立体配置が未解明の計4種のメガスチグマン配糖体の絶対立体配置につきmodified Moscher法を利用することにより明らかにした.","ja":"沖縄産カキバカンコノキおよびシマウリノキから単離されたメガスチグマン配糖体のうち,その一部の絶対立体配置が未解明の計4種のメガスチグマン配糖体の絶対立体配置につきmodified Moscher法を利用することにより明らかにした."},"publication_date":"2003-03","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.62","number":"No.5","starting_page":"763","ending_page":"768","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(02)00614-3"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://cat.inist.fr/?aModele=afficheN&cpsidt=14505327","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12542361","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75505","label":"url"}],"paper_title":{"en":"New icetexane and 20 norabietane diterpenes with trypanocidal activity from Dracocephalum komarovi.","ja":"New icetexane and 20 norabietane diterpenes with trypanocidal activity from Dracocephalum komarovi."},"authors":{"en":[{"name":"Uchiyama Nahoko"},{"name":"Kiuchi Fumiyuki"},{"name":"Ito Michiho"},{"name":"Honda Gisho"},{"name":"Takeda Yoshio"},{"name":"Khodzhimatov K Olimjon"},{"name":"Ashurmetov A Ozodbek"}],"ja":[{"name":"Uchiyama Nahoko"},{"name":"Kiuchi Fumiyuki"},{"name":"Ito Michiho"},{"name":"Honda Gisho"},{"name":"武田 美雄"},{"name":"Khodzhimatov K Olimjon"},{"name":"Ashurmetov A Ozodbek"}]},"description":{"en":"ウズベキスタン産薬用植物Dracocephalum komarovi全草から抗トリパノゾーマ活性を有する新ジテルペン計3種を単離し,その化学構造を明らかにした.","ja":"ウズベキスタン産薬用植物Dracocephalum komarovi全草から抗トリパノゾーマ活性を有する新ジテルペン計3種を単離し,その化学構造を明らかにした."},"publication_date":"2003-01","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.66","number":"No.1","starting_page":"128","ending_page":"131","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np020308z"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12502335","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124821","label":"url"}],"paper_title":{"en":"Sesquiterpenes from Ferula penninervis","ja":"Sesquiterpenes from Ferula penninervis"},"authors":{"en":[{"name":"Shikishima Yasuhiro"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Tori Motoo"},{"name":"Takaoka Shigeru"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Shikishima Yasuhiro"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Tori Motoo"},{"name":"Takaoka Shigeru"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"The ethyl acetate soluble extract of the dried roots of Ferula penninervis gave 17 new sesquiterpenes [15 of the guaiane-type, ferupennins A-O (1-15), and two of the eudesmane-type, 1alpha-hydroxy-2-oxo-5alpha,7beta,11betaH-eudesm-3-en-6alpha,12-olide (16) and penninervin (17)] and nine known sesquiterpenes. The structures of the new compounds were elucidated on the basis of spectroscopic evidence and X-ray analysis. The absolute configuration of ferupennin A (1) was determined by a modified Mosher method.","ja":"The ethyl acetate soluble extract of the dried roots of Ferula penninervis gave 17 new sesquiterpenes [15 of the guaiane-type, ferupennins A-O (1-15), and two of the eudesmane-type, 1alpha-hydroxy-2-oxo-5alpha,7beta,11betaH-eudesm-3-en-6alpha,12-olide (16) and penninervin (17)] and nine known sesquiterpenes. The structures of the new compounds were elucidated on the basis of spectroscopic evidence and X-ray analysis. The absolute configuration of ferupennin A (1) was determined by a modified Mosher method."},"publication_date":"2002-12","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.65","number":"No.12","starting_page":"1897","ending_page":"1903","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np020014d"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://taylorandfrancis.metapress.com/(nthlijqprqnz3hrorcnnxe55)/app/home/contribution.asp?referrer=parent&backto=issue,2,12;journal,34,76;linkingpublicationresults,1:103117,1","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75499","label":"url"}],"paper_title":{"en":"Larvicidal activity of extract and triterpenoids from Lantana camara","ja":"Larvicidal activity of extract and triterpenoids from Lantana camara"},"authors":{"en":[{"name":"Fatope Oladeji Majekodunmi"},{"name":"Salihu Labaran"},{"name":"Asante K Stephen"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Fatope Oladeji Majekodunmi"},{"name":"Salihu Labaran"},{"name":"Asante K Stephen"},{"name":"武田 美雄"}]},"description":{"en":"クマツズラ科植物Lantana camaraのbrine schrimp lethality assayで活性を示す画分より3種のトリテルペンを単離すると共に2種のlarvaeに対する活性を検討した.","ja":"クマツズラ科植物Lantana camaraのbrine schrimp lethality assayで活性を示す画分より3種のトリテルペンを単離すると共に2種のlarvaeに対する活性を検討した."},"publication_date":"2002-12","publication_name":{"en":"Pharmaceutical Biology","ja":"Pharmaceutical Biology"},"volume":"Vol.40","number":"No.8","starting_page":"564","ending_page":"567","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1076/phbi.40.8.564.14654"],"issn":["1388-0209"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://pubs.acs.org/cgi-bin/abstract.cgi/jnprdf/2002/65/i11/abs/np010541h.html","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12444696","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124822","label":"url"}],"paper_title":{"en":"Polysulfide Derivatives from Ferula foetida","ja":"Polysulfide Derivatives from Ferula foetida"},"authors":{"en":[{"name":"Duan Hongquan"},{"name":"Takaishi Yoshihisa"},{"name":"Tori Motoo"},{"name":"Takaoka Shigeru"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov A Ozodebek"}],"ja":[{"name":"Duan Hongquan"},{"name":"高石 喜久"},{"name":"Tori Motoo"},{"name":"Takaoka Shigeru"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov A Ozodebek"}]},"description":{"en":"The ethyl acetate-soluble fraction from a methanol extract of Ferula foetida has afforded six new sulfide derivatives, (E)-3-methylsulfinyl-2-propenyl sec-butyl disulfide (foetisulfide A) (1), (Z)-3-methylsulfinyloxy-2-propenyl sec-butyl disulfide (foetisulfide B) (2), (E)-3-methylsulfinyloxy-2-propenyl sec-butyl disulfide (foetisulfide C) (3), bis(3-methylthio-2E-propenyl) disulfide (foetisulfide D) (4), 3,4,5-trimethyl-2-thiophenecarboxylic acid (foetithiophene A) (5), 3,4,5-trimethyl-2-(methylsulfinyloxymethyl)thiophene (foetithiophene B) (6), along with six known compounds. The structures of 1-6 were established on the basis of spectroscopic studies, with the elucidation of 5 confirmed by single-crystal X-ray crystallography.","ja":"The ethyl acetate-soluble fraction from a methanol extract of Ferula foetida has afforded six new sulfide derivatives, (E)-3-methylsulfinyl-2-propenyl sec-butyl disulfide (foetisulfide A) (1), (Z)-3-methylsulfinyloxy-2-propenyl sec-butyl disulfide (foetisulfide B) (2), (E)-3-methylsulfinyloxy-2-propenyl sec-butyl disulfide (foetisulfide C) (3), bis(3-methylthio-2E-propenyl) disulfide (foetisulfide D) (4), 3,4,5-trimethyl-2-thiophenecarboxylic acid (foetithiophene A) (5), 3,4,5-trimethyl-2-(methylsulfinyloxymethyl)thiophene (foetithiophene B) (6), along with six known compounds. The structures of 1-6 were established on the basis of spectroscopic studies, with the elucidation of 5 confirmed by single-crystal X-ray crystallography."},"publication_date":"2002-11","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.65","number":"No.11","starting_page":"1667","ending_page":"1669","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np010541h"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://ci.nii.ac.jp/naid/110008732205/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520290884137604096/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0036814788&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62749","label":"url"}],"paper_title":{"en":"A new megastigmane glucoside from Phlomis spinidens","ja":"A new megastigmane glucoside from Phlomis spinidens"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Isai Natsuko"},{"name":"Masuda Toshiya"},{"name":"Otsuka Hideaki"},{"name":"Honda Gisho"},{"name":"Takaishi Yoshihisa"},{"name":"Kiuchi Fumiyuki"},{"name":"Ito Michiho"},{"name":"Ashurmetov A Ozodebek"},{"name":"Khodzhimatov K Olimjon"}],"ja":[{"name":"武田 美雄"},{"name":"Isai Natsuko"},{"name":"増田 俊哉"},{"name":"Otsuka Hideaki"},{"name":"Honda Gisho"},{"name":"高石 喜久"},{"name":"Kiuchi Fumiyuki"},{"name":"Ito Michiho"},{"name":"Ashurmetov A Ozodebek"},{"name":"Khodzhimatov K Olimjon"}]},"description":{"en":"A new megastigmane glucoside, phlomisionoside (1) was isolated from the aerial parts of Phlomis spinidens and the structure was elucidated by spectroscopic and chemical analyses.","ja":"ウズベキスタン産しそ科植物Phlomis spinidensの微量成分を検索し,phlomisionosideと命名したメガスチグマン配糖体を単離し,その化学構造を明らかにした."},"publication_date":"2002-10-20","publication_name":{"en":"Natural Medicines","ja":"Natural Medicines"},"volume":"Vol.56","number":"No.5","starting_page":"200","ending_page":"203","languages":["eng"],"referee":true,"identifiers":{"issn":["1340-3443"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=63084","label":"url"}],"paper_title":{"en":"Cytotoxic Activity of Quinone Derivatives of Phenolic Diterpenes from Sage","ja":"Cytotoxic Activity of Quinone Derivatives of Phenolic Diterpenes from Sage"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Oyama Yasuo"},{"name":"Arata Tomohiro"},{"name":"Inaba Yuzuru"},{"name":"Takeda Yoshio"}],"ja":[{"name":"増田 俊哉"},{"name":"小山 保夫"},{"name":"Arata Tomohiro"},{"name":"Inaba Yuzuru"},{"name":"武田 美雄"}]},"publication_date":"2002-10-10","publication_name":{"en":"ITE Letters","ja":"ITE Letters"},"volume":"Vol.3","number":"No.1","starting_page":"39","ending_page":"42","languages":["eng"],"referee":true,"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/110003615087/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001204163020544/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62738","label":"url"}],"paper_title":{"en":"An iridoid glucoside dimer and non-glycosidic iridoid from the leaves of Lasianthus wallichii","ja":"An iridoid glucoside dimer and non-glycosidic iridoid from the leaves of Lasianthus wallichii"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Shimidzu Hideko"},{"name":"Mizuno Kennta"},{"name":"Inouchi Sachiyo"},{"name":"Masuda Toshiya"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsutaka"},{"name":"Otsuka Hideaki"}],"ja":[{"name":"武田 美雄"},{"name":"Shimidzu Hideko"},{"name":"Mizuno Kennta"},{"name":"Inouchi Sachiyo"},{"name":"増田 俊哉"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Aramoto Mitsutaka"},{"name":"Otsuka Hideaki"}]},"description":{"en":"沖縄産アカネ科植物マルバルリミノキ葉部の配糖体成分を検索し5種の既知化合物と共に,新非配糖体イリドイドおよびイリドイド配糖体2量体を単離し,その化学構造を明らかにした.","ja":"沖縄産アカネ科植物マルバルリミノキ葉部の配糖体成分を検索し5種の既知化合物と共に,新非配糖体イリドイドおよびイリドイド配糖体2量体を単離し,その化学構造を明らかにした."},"publication_date":"2002-10-01","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.50","number":"No.10","starting_page":"1395","ending_page":"1397","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.50.1395"],"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12350156","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=68232","label":"url"}],"paper_title":{"en":"An Unusual Sesquiterpene Derivative from Ferula Kuhistanica","ja":"An Unusual Sesquiterpene Derivative from Ferula Kuhistanica"},"authors":{"en":[{"name":"Tamemoto Kimiko"},{"name":"Takaishi Yoshihisa"},{"name":"Kawazoe Kazuyoshi"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Kiuchi Fumiyuki"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"},{"name":"Shimizu Katsuhide"},{"name":"Nagasawa Hideko"},{"name":"Uto Yoshihiro"},{"name":"Hori Hitoshi"}],"ja":[{"name":"Tamemoto Kimiko"},{"name":"高石 喜久"},{"name":"川添 和義"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Kiuchi Fumiyuki"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"},{"name":"Shimizu Katsuhide"},{"name":"永澤 秀子"},{"name":"宇都 義浩"},{"name":"堀 均"}]},"description":{"en":"Ferula Kuhistanicaより単離したセスキテルペン誘導体の構造決定と活性を明らかにした.","ja":"Ferula Kuhistanicaより単離したセスキテルペン誘導体の構造決定と活性を明らかにした."},"publication_date":"2002-09","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.65","number":"No.9","starting_page":"1323","ending_page":"1324","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np020020+"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://cat.inist.fr/?aModele=afficheN&cpsidt=13682552","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12036019","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62817","label":"url"}],"paper_title":{"en":"Turpinionosides A-E; megastigmane glucosides from leaves of Turpinia ternata","ja":"Turpinionosides A-E; megastigmane glucosides from leaves of Turpinia ternata"},"authors":{"en":[{"name":"Yu Qian"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Yu Qian"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"武田 美雄"}]},"description":{"en":"沖縄産ミツバウツギ科植物,ショウベンノキ葉部の配糖体成分を検索しturpinionosides A-Eと命名したメガスチグマン配糖体5種を単離し,その化学構造を明らかにした.","ja":"沖縄産ミツバウツギ科植物,ショウベンノキ葉部の配糖体成分を検索しturpinionosides A-Eと命名したメガスチグマン配糖体5種を単離し,その化学構造を明らかにした."},"publication_date":"2002-05","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.50","number":"No.5","starting_page":"640","ending_page":"644","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.50.640"],"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11958616","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62776","label":"url"}],"paper_title":{"en":"Structural Identification of New Curcumin Dimers and Their Contribution to the Antioxidant Mechanism","ja":"Structural Identification of New Curcumin Dimers and Their Contribution to the Antioxidant Mechanism"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Toi Yukiko"},{"name":"Bando Hiromi"},{"name":"Maekawa Tomomi"},{"name":"Takeda Yoshio"},{"name":"Yamaguchi Hidemasa"}],"ja":[{"name":"増田 俊哉"},{"name":"Toi Yukiko"},{"name":"Bando Hiromi"},{"name":"Maekawa Tomomi"},{"name":"武田 美雄"},{"name":"Yamaguchi Hidemasa"}]},"description":{"en":"As a part of the research project on the elucidation of the chain-breaking antioxidant mechanism of natural phenolics against the oxidation of food components, curcumin, a main turmeric pigment, was investigated. A relatively high concentration of curcumin gave three dimers as radical termination products in addition to the coupling products with curcumin and the lipid hydroperoxide. The structural analysis of these dimers and quantitative analysis of their production rates revealed that radical-radical termination mainly occurred at the 2-position of curcumin. The contribution of the pathway for production of these dimers to the antioxidant mechanism of curcumin was estimated from the concentration-dependent data of the antioxidant activity and formation rates of these termination products. The A-A termination (dimer formation) was estimated to contribute at least about 40% of the entire antioxidant process against ethyl linoleate oxidation.","ja":"As a part of the research project on the elucidation of the chain-breaking antioxidant mechanism of natural phenolics against the oxidation of food components, curcumin, a main turmeric pigment, was investigated. A relatively high concentration of curcumin gave three dimers as radical termination products in addition to the coupling products with curcumin and the lipid hydroperoxide. The structural analysis of these dimers and quantitative analysis of their production rates revealed that radical-radical termination mainly occurred at the 2-position of curcumin. The contribution of the pathway for production of these dimers to the antioxidant mechanism of curcumin was estimated from the concentration-dependent data of the antioxidant activity and formation rates of these termination products. The A-A termination (dimer formation) was estimated to contribute at least about 40% of the entire antioxidant process against ethyl linoleate oxidation."},"publication_date":"2002-05","publication_name":{"en":"Journal of Agricultural and Food Chemistry","ja":"Journal of Agricultural and Food Chemistry"},"volume":"Vol.50","number":"No.9","starting_page":"2524","ending_page":"2530","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/jf011601s"],"issn":["0021-8561"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://pubs.acs.org/cgi-bin/abstract.cgi/jnprdf/2002/65/i05/abs/np010620t.html","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12027742","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62757","label":"url"}],"paper_title":{"en":"Tricalysiosides A-G; Rearranged ent-kaurenoid glycosides from the leaves of Tricalysia dubia","ja":"Tricalysiosides A-G; Rearranged ent-kaurenoid glycosides from the leaves of Tricalysia dubia"},"authors":{"en":[{"name":"He Dong-Hui"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Bando Masahiko"},{"name":"Takeda Yoshio"}],"ja":[{"name":"He Dong-Hui"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Bando Masahiko"},{"name":"武田 美雄"}]},"description":{"en":"Seven rearranged ent-kaurane glycosides, named tricalysiosides A-G (1-7), were isolated from the leaves of Tricalysia dubia collected on Okinawa Island. Their C-18 and 19 methyls were found to have rearranged to form an alpha,beta-unsaturated gamma-lactone ring, with other functional groups remotely located only on C-15, -16, and -17 of the five-membered ring. Information available from various kinds of two-dimensional NMR spectra was limited and insufficient to allow total characterization of the structures. Finally, using X-ray crystallographic analysis, the structure of tricalysioside A (1) was determined to be 4-nor-18-homo-ent-kauran-4(18)-en-15beta,16beta,17-triol-3beta,19-olide 16-O-beta-D-glucopyranoside (1). On the basis of the crystal structure of 1, the structures of the other tricalysiosides (2-7) were also established.","ja":"沖縄産アカネ科植物シロミミズ葉部の配糖体成分を検索した結果,新転移ーent-カウラノイド配糖体7種を単離し,X線結晶解析を含む手法を用いてその構造を明らかにした."},"publication_date":"2002-05","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.65","number":"No.5","starting_page":"685","ending_page":"688","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np010620t"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1016/S0031-9422(02)00023-7","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11867097","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1573950401491313792/","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124827","label":"url"}],"paper_title":{"en":"Coumarins and γ-pyrone derivatives from Prangos pabularia: antibacterial activity and inhibition of cytokine release","ja":"Coumarins and γ-pyrone derivatives from Prangos pabularia: antibacterial activity and inhibition of cytokine release"},"authors":{"en":[{"name":"Tada Yukiko"},{"name":"Shikishima Yasuhiro"},{"name":"Takaishi Yoshihisa"},{"name":"Shibata Hirofumi"},{"name":"Higuti Tomihiko"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"},{"name":"Ohmoto Yasukazu"}],"ja":[{"name":"Tada Yukiko"},{"name":"Shikishima Yasuhiro"},{"name":"高石 喜久"},{"name":"柴田 洋文"},{"name":"樋口 富彦"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"},{"name":"Ohmoto Yasukazu"}]},"publication_date":"2002-03","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.59","number":"No.6","starting_page":"649","ending_page":"654","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(02)00023-7"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11908967","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124826","label":"url"}],"paper_title":{"en":"Benzoylphloroglucinol Derivatives from Hypericum scabrum","ja":"Benzoylphloroglucinol Derivatives from Hypericum scabrum"},"authors":{"en":[{"name":"Matsuhisa Michiko"},{"name":"Shikishima Yasuhiro"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Shibata Hirofumi"},{"name":"Higuti Tomihiko"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Matsuhisa Michiko"},{"name":"Shikishima Yasuhiro"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"柴田 洋文"},{"name":"樋口 富彦"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"Nine new polyprenylated benzoylphloroglucinol derivatives, hyperibones A-I (1-9), were isolated from the aerial parts of the Uzbekistan medicinal plant Hypericum scabrum. Their structures were determined mainly on the basis of spectroscopic evidence (2D NMR and HRMS). Compounds 1, 2, and 4 showed mild in vitro antibacterial activity against methicillin-resistance Staphylococus aureus (MRSA) and methicillin-sensitive Staphylococus aureus (MSSA).","ja":"Nine new polyprenylated benzoylphloroglucinol derivatives, hyperibones A-I (1-9), were isolated from the aerial parts of the Uzbekistan medicinal plant Hypericum scabrum. Their structures were determined mainly on the basis of spectroscopic evidence (2D NMR and HRMS). Compounds 1, 2, and 4 showed mild in vitro antibacterial activity against methicillin-resistance Staphylococus aureus (MRSA) and methicillin-sensitive Staphylococus aureus (MSSA)."},"publication_date":"2002-03","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.65","number":"No.3","starting_page":"290","ending_page":"294","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np010310a"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11860708","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62753","label":"url"}],"paper_title":{"en":"Contribution of a combination of ponicidin and acyclovir/gancyclovir to the antitumor effifiency of the herpes simplex virus thymidine kinase gene therapy system","ja":"Contribution of a combination of ponicidin and acyclovir/gancyclovir to the antitumor effifiency of the herpes simplex virus thymidine kinase gene therapy system"},"authors":{"en":[{"name":"Hayashi Kyoko"},{"name":"Hayashi Toshimitsu"},{"name":"Sun Han-dong"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Hayashi Kyoko"},{"name":"Hayashi Toshimitsu"},{"name":"Sun Han-dong"},{"name":"武田 美雄"}]},"description":{"en":"しそ科植物より単離されたジテルペン,ponicidinがherpes simplex virus thymidine kinase gene therapy 系の抗腫瘍活性にacyclovir/ganciclovirと併用した場合に抗腫瘍活性を増大させることをin vivoの実験により明らかにした.","ja":"しそ科植物より単離されたジテルペン,ponicidinがherpes simplex virus thymidine kinase gene therapy 系の抗腫瘍活性にacyclovir/ganciclovirと併用した場合に抗腫瘍活性を増大させることをin vivoの実験により明らかにした."},"publication_date":"2002-02-10","publication_name":{"en":"Human Gene Therapy","ja":"Human Gene Therapy"},"volume":"Vol.13","number":"No.3","starting_page":"415","ending_page":"423","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1089/10430340252792549"],"issn":["1043-0342"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-10844245669&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=65857","label":"url"}],"paper_title":{"en":"Antioxidant-related activities of ethanol extracts from edible and medicinal plants cultivated in Okinawa, Japan","ja":"沖縄産食薬用植物エタノール抽出物の抗酸化関連活性"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Oyama Yasuo"},{"name":"Inaba Y."},{"name":"Toi Yukiko"},{"name":"Arata Tomohiro"},{"name":"Takeda Yoshio"},{"name":"Nakamoto Katsuo"},{"name":"Kuninaga Hideki"},{"name":"Nishisato Saori"},{"name":"Nonaka Ryo"}],"ja":[{"name":"増田 俊哉"},{"name":"小山 保夫"},{"name":"稲葉 譲"},{"name":"戸井 由紀子"},{"name":"荒田 智裕"},{"name":"武田 美雄"},{"name":"仲本 勝男"},{"name":"國永 秀樹"},{"name":"西里 さおり"},{"name":"野中 亮"}]},"publication_date":"2002-01-01","publication_name":{"en":"Nippon Shokuhin Kagaku Kogaku Kaishi","ja":"日本食品科学工学会誌"},"volume":"Vol.49","number":"No.10","starting_page":"652","ending_page":"661","languages":["jpn"],"referee":true,"identifiers":{"doi":["10.3136/nskkk.49.652"],"issn":["1341-027X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12112292","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=63086","label":"url"}],"paper_title":{"en":"Flow Cytometric Estimation on Cytotoxic Activity of Leaf Extracts from Seashore Plants in Subtropical Japan: Isolation, Quantification and Cytotoxic Action of (-)-Deoxypodpphyllotoxin","ja":"Flow Cytometric Estimation on Cytotoxic Activity of Leaf Extracts from Seashore Plants in Subtropical Japan: Isolation, Quantification and Cytotoxic Action of (-)-Deoxypodpphyllotoxin"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Oyama Yasuo"},{"name":"Yonemori Shigetomo"},{"name":"Takeda Yoshio"},{"name":"Yamanazaki Yuko"},{"name":"Mizuguchi Shinichi"},{"name":"Nakata Mami"},{"name":"Tanaka Tomochika"}],"ja":[{"name":"増田 俊哉"},{"name":"小山 保夫"},{"name":"Yonemori Shigetomo"},{"name":"武田 美雄"},{"name":"Yamanazaki Yuko"},{"name":"Mizuguchi Shinichi"},{"name":"Nakata Mami"},{"name":"Tanaka Tomochika"}]},"description":{"en":"The cytotoxic activity of methanol extracts of leaves collected from 39 seashore plants in Iriomote Island, subtropical Japan was examined on human leukaemia cells (K562 cells) using a flow cytometer with two fluorescent probes, ethidium bromide and annexin V-FITC. Five extracts (10 microg/mL) from Hernandia nymphaeaefolia, Cerbera manghas, Pongamia pinnata, Morus australis var. glabra and Thespesia populnea greatly inhibited the growth of K562 cells. When the concentration was decreased to 1 microg/mL, only one extract from H. nymphaeaefolia still inhibited the cell growth. A cytotoxic compound was isolated from the leaves by bioassay-guided fractionation and was identified as (-)-deoxypodophyllotoxin (DPT). The fresh leaves of H. nymphaeaefolia contained a remarkably high amount of DPT (0.21 +/- 0.07% of fresh leaf weight), being clarified by a quantitative HPLC analysis. DPT at 70-80 pM started to inhibit the growth of K562 cells in an all-or-none fashion and at 100 pM or more it produced complete inhibition in all cases. Therefore, the slope of the dose-response curve was very steep. DPT at 100 pM or more decreased the cell viability to 50%-60% and increased the number of cells undergoing apoptosis (annexin V-positive cells). The results indicate that DPT contributes to the cytotoxic action of the extract from the leaves of H. nymphaeaefolia on K562 cells.","ja":"The cytotoxic activity of methanol extracts of leaves collected from 39 seashore plants in Iriomote Island, subtropical Japan was examined on human leukaemia cells (K562 cells) using a flow cytometer with two fluorescent probes, ethidium bromide and annexin V-FITC. Five extracts (10 microg/mL) from Hernandia nymphaeaefolia, Cerbera manghas, Pongamia pinnata, Morus australis var. glabra and Thespesia populnea greatly inhibited the growth of K562 cells. When the concentration was decreased to 1 microg/mL, only one extract from H. nymphaeaefolia still inhibited the cell growth. A cytotoxic compound was isolated from the leaves by bioassay-guided fractionation and was identified as (-)-deoxypodophyllotoxin (DPT). The fresh leaves of H. nymphaeaefolia contained a remarkably high amount of DPT (0.21 +/- 0.07% of fresh leaf weight), being clarified by a quantitative HPLC analysis. DPT at 70-80 pM started to inhibit the growth of K562 cells in an all-or-none fashion and at 100 pM or more it produced complete inhibition in all cases. Therefore, the slope of the dose-response curve was very steep. DPT at 100 pM or more decreased the cell viability to 50%-60% and increased the number of cells undergoing apoptosis (annexin V-positive cells). The results indicate that DPT contributes to the cytotoxic action of the extract from the leaves of H. nymphaeaefolia on K562 cells."},"publication_date":"2002-01-01","publication_name":{"en":"Phytotherapy Research","ja":"Phytotherapy Research"},"volume":"Vol.16","number":"No.4","starting_page":"353","ending_page":"358","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1002/ptr.902"],"issn":["0951-418X"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://cat.inist.fr/?aModele=afficheN&cpsidt=13424372","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11782207","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62819","label":"url"}],"paper_title":{"en":"Monoacylglycerol from Punica granatum seed oil","ja":"Monoacylglycerol from Punica granatum seed oil"},"authors":{"en":[{"name":"Fatope Oladeji Majekodunmi"},{"name":"AlBurtomani S Suad Khamis"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Fatope Oladeji Majekodunmi"},{"name":"AlBurtomani S Suad Khamis"},{"name":"武田 美雄"}]},"description":{"en":"健康に資する天然物探索の一環としてザクロ種子油の成分を検索し,主成分として1-O-trans,cis,trans-9,11,13-octadecatrienoyl glycerolを単離,同定した.","ja":"健康に資する天然物探索の一環としてザクロ種子油の成分を検索し,主成分として1-O-trans,cis,trans-9,11,13-octadecatrienoyl glycerolを単離,同定した."},"publication_date":"2002-01","publication_name":{"en":"Journal of Agricultural and Food Chemistry","ja":"Journal of Agricultural and Food Chemistry"},"volume":"Vol.50","number":"No.2","starting_page":"357","ending_page":"360","languages":["eng"],"referee":true,"identifiers":{"issn":["0021-8561"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/12358451","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62735","label":"url"}],"paper_title":{"en":"Recovery Mechanism of the Antioxidant Activity from Carnosic Acid Quinone, an Oxidized Sage and Rosemary Antioxidant","ja":"Recovery Mechanism of the Antioxidant Activity from Carnosic Acid Quinone, an Oxidized Sage and Rosemary Antioxidant"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Inaba Yuzuru"},{"name":"Maekawa Tomomi"},{"name":"Takeda Yoshio"},{"name":"Tamura Tadatoshi"},{"name":"Yamaguchi Hidemasa"}],"ja":[{"name":"増田 俊哉"},{"name":"Inaba Yuzuru"},{"name":"Maekawa Tomomi"},{"name":"武田 美雄"},{"name":"Tamura Tadatoshi"},{"name":"Yamaguchi Hidemasa"}]},"description":{"en":"A solution of carnosic acid quinone, which is a radical chain-termination product having no antioxidant activity in the antioxidant reaction of carnosic acid, recovers potent antioxidant activity upon standing. The HPLC analysis of an aged solution of carnosic acid quinone revealed that several antioxidants are produced in the solution. From the time-course and quantitative analyses of the formation of the products and their structural analysis, an antioxidant mechanism from carnosic acid quinone is proposed that includes a redox reaction of carnosic acid quinone in addition to the isomerization to lactone derivatives. In the first stage of antioxidation, carnosic acid, the reduction product from carnosic acid quinone, contributes to the potent antioxidant activity of the solution. This proposed mechanism can explain one of the reasons for the strong antioxidant activity of the extract of the popular herbs sage and rosemary.","ja":"A solution of carnosic acid quinone, which is a radical chain-termination product having no antioxidant activity in the antioxidant reaction of carnosic acid, recovers potent antioxidant activity upon standing. The HPLC analysis of an aged solution of carnosic acid quinone revealed that several antioxidants are produced in the solution. From the time-course and quantitative analyses of the formation of the products and their structural analysis, an antioxidant mechanism from carnosic acid quinone is proposed that includes a redox reaction of carnosic acid quinone in addition to the isomerization to lactone derivatives. In the first stage of antioxidation, carnosic acid, the reduction product from carnosic acid quinone, contributes to the potent antioxidant activity of the solution. This proposed mechanism can explain one of the reasons for the strong antioxidant activity of the extract of the popular herbs sage and rosemary."},"publication_date":"2002-01","publication_name":{"en":"Journal of Agricultural and Food Chemistry","ja":"Journal of Agricultural and Food Chemistry"},"volume":"Vol.50","number":"No.21","starting_page":"5863","ending_page":"5869","languages":["eng"],"referee":true,"identifiers":{"issn":["0021-8561"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1016/S0031-9422(01)00334-X","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11730877","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0035818769&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124828","label":"url"}],"paper_title":{"en":"A bis-sesquiterpene and sesquiterpenolides from Inula macrophylla","ja":"A bis-sesquiterpene and sesquiterpenolides from Inula macrophylla"},"authors":{"en":[{"name":"Fu Bo"},{"name":"Su Bao-Ning"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Fu Bo"},{"name":"Su Bao-Ning"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"Macrophyllidimer C, a novel bis-sesquiterpene, in which the two sesquiterpene units are directly connected by a C-C bond, and eight other sesquiterpenolides were obtained from the bark of Inula macrophylla. Seven of these, macrophyllilactones A-G, are new eudesmanolide- and elemanolide-type sesquiterpenes. Their structures were determined on the basis of spectroscopic evidence and chemical reaction.","ja":"Macrophyllidimer C, a novel bis-sesquiterpene, in which the two sesquiterpene units are directly connected by a C-C bond, and eight other sesquiterpenolides were obtained from the bark of Inula macrophylla. Seven of these, macrophyllilactones A-G, are new eudesmanolide- and elemanolide-type sesquiterpenes. Their structures were determined on the basis of spectroscopic evidence and chemical reaction."},"publication_date":"2001-12","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.58","number":"No.7","starting_page":"1121","ending_page":"1128","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(01)00334-X"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1016/S0031-9422(01)00307-7","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11672742","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0035900473&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124829","label":"url"}],"paper_title":{"en":"Sesquiterpenoids from the fruits of Ferula kuhistanica and antibacterial activity of the constituents of F. kuhistanica","ja":"Sesquiterpenoids from the fruits of Ferula kuhistanica and antibacterial activity of the constituents of F. kuhistanica"},"authors":{"en":[{"name":"Tamemoto Kimiko"},{"name":"Takaishi Yoshihisa"},{"name":"Chen Bei"},{"name":"Kawazoe Kazuyoshi"},{"name":"Shibata Hirofumi"},{"name":"Higuti Tomihiko"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Tamemoto Kimiko"},{"name":"高石 喜久"},{"name":"Chen Bei"},{"name":"川添 和義"},{"name":"柴田 洋文"},{"name":"樋口 富彦"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"Ethyl acetate extracts of the air-dried fruits of Ferula kuhistanica afforded three daucane esters: kuhistanicaol H, I and J, together with nine other known compounds. Their structures were established on the basis of spectroscopic evidence. Isolated compounds in this paper and previously reported compounds from the roots and stems of F. kuhistanica were tested for antibacterial activity. Some of them were selectively toxic against Gram-positive bacteria, including methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MSSA and MRSA).","ja":"Ethyl acetate extracts of the air-dried fruits of Ferula kuhistanica afforded three daucane esters: kuhistanicaol H, I and J, together with nine other known compounds. Their structures were established on the basis of spectroscopic evidence. Isolated compounds in this paper and previously reported compounds from the roots and stems of F. kuhistanica were tested for antibacterial activity. Some of them were selectively toxic against Gram-positive bacteria, including methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MSSA and MRSA)."},"publication_date":"2001-11","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.58","number":"No.5","starting_page":"763","ending_page":"767","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(01)00307-7"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62820","label":"url"}],"paper_title":{"en":"Myrisinionosides A-E: megastigmane glycosides from leaves of Myrisine sequinii","ja":"Myrisinionosides A-E: megastigmane glycosides from leaves of Myrisine sequinii"},"authors":{"en":[{"name":"Otsuka Hideaki"},{"name":"Zhong Xi-Ning"},{"name":"Hirata Eiji"},{"name":"Tkakazu Shinzato"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Otsuka Hideaki"},{"name":"Zhong Xi-Ning"},{"name":"Hirata Eiji"},{"name":"Tkakazu Shinzato"},{"name":"武田 美雄"}]},"description":{"en":"沖縄産Myrisine sequinii葉部の配糖体成分を検索した結果,5種の新メガスチグマン配糖体を単離し,その化学構造を明らかにした.","ja":"沖縄産Myrisine sequinii葉部の配糖体成分を検索した結果,5種の新メガスチグマン配糖体を単離し,その化学構造を明らかにした."},"publication_date":"2001-09","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.49","number":"No.9","starting_page":"1093","ending_page":"1097","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62822","label":"url"}],"paper_title":{"en":"Phlomisflavosides A and B, new flavonol diglycosides from Phlomis spinidens","ja":"Phlomisflavosides A and B, new flavonol diglycosides from Phlomis spinidens"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Isai Natsuko"},{"name":"Masuda Toshiya"},{"name":"Honda Gisho"},{"name":"Takaishi Yoshihisa"},{"name":"Ito Michiho"},{"name":"Otsuka Hideaki"},{"name":"Ashurmetov A Ozodebek"},{"name":"Khodzhimatov K Olimjon"}],"ja":[{"name":"武田 美雄"},{"name":"Isai Natsuko"},{"name":"増田 俊哉"},{"name":"Honda Gisho"},{"name":"高石 喜久"},{"name":"Ito Michiho"},{"name":"Otsuka Hideaki"},{"name":"Ashurmetov A Ozodebek"},{"name":"Khodzhimatov K Olimjon"}]},"description":{"en":"ウズベキスタン産シソ科植物Phlomis spinidensの配糖体成分を検索し,新フラボノールdiglycosides,phlomisflavosides A, Bを単離し,その化学構造を明らかにした.","ja":"ウズベキスタン産シソ科植物Phlomis spinidensの配糖体成分を検索し,新フラボノールdiglycosides,phlomisflavosides A, Bを単離し,その化学構造を明らかにした."},"publication_date":"2001-08","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.49","number":"No.8","starting_page":"1039","ending_page":"1041","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://www.jstage.jst.go.jp/article/cpb/49/7/49_877/_article/-char/ja/","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11456095","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001204160938368/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0034935950&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124830","label":"url"}],"paper_title":{"en":"Chemical Constituents of Prangos tschimganica; Structure Elucidation and Absolute Configuration of Coumarin and Furanocoumarin Derivatives with Anti-HIV Activity","ja":"Chemical Constituents of Prangos tschimganica; Structure Elucidation and Absolute Configuration of Coumarin and Furanocoumarin Derivatives with Anti-HIV Activity"},"authors":{"en":[{"name":"Shikishima Yasuhiro"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"},{"name":"Lee Kuo-Hsing"}],"ja":[{"name":"Shikishima Yasuhiro"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"},{"name":"Lee Kuo-Hsing"}]},"description":{"en":"The methanol extract of the dried aerial parts of Prangos tschimganica gave three new coumarin derivatives and 30 known coumarin derivatives. Their structures were established on the basis of chemical and spectroscopic evidence. Absolute configuration of the isolated compounds were determined by using a modified Mosher's method. Some of the isolated compounds showed anti-HIV activity.","ja":"The methanol extract of the dried aerial parts of Prangos tschimganica gave three new coumarin derivatives and 30 known coumarin derivatives. Their structures were established on the basis of chemical and spectroscopic evidence. Absolute configuration of the isolated compounds were determined by using a modified Mosher's method. Some of the isolated compounds showed anti-HIV activity."},"publication_date":"2001-07-01","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.49","number":"No.7","starting_page":"877","ending_page":"880","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.49.877"],"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62827","label":"url"}],"paper_title":{"en":"Glochiflavanosides A-D:flavanol glucosides from the leaves of Glochidion zeylanicum (Gaertn.) A Juss.","ja":"Glochiflavanosides A-D:flavanol glucosides from the leaves of Glochidion zeylanicum (Gaertn.) A Juss."},"authors":{"en":[{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Shinzato Takakazu"},{"name":"武田 美雄"}]},"description":{"en":"沖縄産トウダイグサ科植物カキバカンコノキ葉部より4種のフラバノール配糖体,glochiflavanosidesA-Dを単離し,その化学構造を明らかにした.","ja":"沖縄産トウダイグサ科植物カキバカンコノキ葉部より4種のフラバノール配糖体,glochiflavanosidesA-Dを単離し,その化学構造を明らかにした."},"publication_date":"2001-07","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.49","number":"No.7","starting_page":"921","ending_page":"923","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://www.jstage.jst.go.jp/article/cpb/49/6/49_707/_article/-char/ja/","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11411521","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1390001204164185472/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0034954317&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124834","label":"url"}],"paper_title":{"en":"Farnesyl Hydroxybenzoic Acid Derivatives from Ferula kuhistanica","ja":"Farnesyl Hydroxybenzoic Acid Derivatives from Ferula kuhistanica"},"authors":{"en":[{"name":"Chen Bei"},{"name":"Takaishi Yoshihisa"},{"name":"Kawazoe Kazuyoshi"},{"name":"Tamemoto Kimiko"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Chen Bei"},{"name":"高石 喜久"},{"name":"川添 和義"},{"name":"Tamemoto Kimiko"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"Four new farnesyl hydroxybenzoic acid derivatives, kuhistanols E-H(1-4), were isolated from the roots of the Uzbekistan medicinal plant Ferula kuhistanica. The structures of the new compounds were elucidated based on spectroscopic and chemical evidence.","ja":"Four new farnesyl hydroxybenzoic acid derivatives, kuhistanols E-H(1-4), were isolated from the roots of the Uzbekistan medicinal plant Ferula kuhistanica. The structures of the new compounds were elucidated based on spectroscopic and chemical evidence."},"publication_date":"2001-06-01","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.49","number":"No.6","starting_page":"707","ending_page":"710","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.49.707"],"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11471728","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0035379252&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=63092","label":"url"}],"paper_title":{"en":"Isolation and Antioxidant Activity of the Galloyl Flavonol Glycosides from a Seashore Plant, Pemphis acidula","ja":"Isolation and Antioxidant Activity of the Galloyl Flavonol Glycosides from a Seashore Plant, Pemphis acidula"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Iritani Kumiko"},{"name":"Yonemori Shigetomo"},{"name":"Oyama Yasuo"},{"name":"Takeda Yoshio"}],"ja":[{"name":"増田 俊哉"},{"name":"Iritani Kumiko"},{"name":"Yonemori Shigetomo"},{"name":"小山 保夫"},{"name":"武田 美雄"}]},"description":{"en":"Four kinds of galloyl flavonol glycosides were found in the leaf extract of Pemphis acidula, a plant growing on the subtropical seashore. Their chemical structures were elucidated to be quercetin or kaempferol 6\"-O-galloyl-beta-D-glycosides by using spectroscopic and chemical analyses. One of the flavonols, kaempferol-3-O-(6-O-galloyl-beta-D-galactopyranoside), was newly isolated from natural sources and its structure was completely determined in this investigation. The antioxidant-related activities of the galloyl flavonoids were examined by the DPPH antiradical activity, inhibition of methyl linoleate oxidation, and inhibition of oxidative cell death. These results were compared with those of the corresponding non-galloylated flavonol glycosides and their aglycones. The galloyl flavonoids showed more efficient activity than that of the corresponding flavonol glycosides, but not more than that of the corresponding aglycones in the three assays applied.","ja":"Four kinds of galloyl flavonol glycosides were found in the leaf extract of Pemphis acidula, a plant growing on the subtropical seashore. Their chemical structures were elucidated to be quercetin or kaempferol 6\"-O-galloyl-beta-D-glycosides by using spectroscopic and chemical analyses. One of the flavonols, kaempferol-3-O-(6-O-galloyl-beta-D-galactopyranoside), was newly isolated from natural sources and its structure was completely determined in this investigation. The antioxidant-related activities of the galloyl flavonoids were examined by the DPPH antiradical activity, inhibition of methyl linoleate oxidation, and inhibition of oxidative cell death. These results were compared with those of the corresponding non-galloylated flavonol glycosides and their aglycones. The galloyl flavonoids showed more efficient activity than that of the corresponding flavonol glycosides, but not more than that of the corresponding aglycones in the three assays applied."},"publication_date":"2001-06","publication_name":{"en":"Bioscience, Biotechnology, and Biochemistry","ja":"Bioscience, Biotechnology, and Biochemistry"},"volume":"Vol.65","number":"No.6","starting_page":"1302","ending_page":"1309","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1271/bbb.65.1302"],"issn":["0916-8451"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11714360","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0035183667&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=63088","label":"url"}],"paper_title":{"en":"Antioxidant Mechanism of Carnosic Acid: Structural Identification of Two Oxidation Products","ja":"Antioxidant Mechanism of Carnosic Acid: Structural Identification of Two Oxidation Products"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Inaba Yuzuru"},{"name":"Takeda Yoshio"}],"ja":[{"name":"増田 俊哉"},{"name":"Inaba Yuzuru"},{"name":"武田 美雄"}]},"description":{"en":"To determine the antioxidant mechanism of food phenolics against the oxidation of food components, the reaction of carnosic acid, an antioxidative constituent of the popular herbs sage and rosemary, was investigated in the presence of ethyl linoleate and the radical oxidation initiator 2,2'-azobis(2,4-dimethylvaleronitrile). During this process, carnosic acid was oxidized to an o-quinone and a hydroxy p-quinone, the chemical structures of which were confirmed by physical and chemical techniques. From a quantitative time course analysis of the production of these quinones, an antioxidant mechanism of carnosic acid is proposed, consisting of the oxidative coupling reaction with the peroxyl radical at the 12- or 14-position of carnosic acid and subsequent degradation reactions.","ja":"To determine the antioxidant mechanism of food phenolics against the oxidation of food components, the reaction of carnosic acid, an antioxidative constituent of the popular herbs sage and rosemary, was investigated in the presence of ethyl linoleate and the radical oxidation initiator 2,2'-azobis(2,4-dimethylvaleronitrile). During this process, carnosic acid was oxidized to an o-quinone and a hydroxy p-quinone, the chemical structures of which were confirmed by physical and chemical techniques. From a quantitative time course analysis of the production of these quinones, an antioxidant mechanism of carnosic acid is proposed, consisting of the oxidative coupling reaction with the peroxyl radical at the 12- or 14-position of carnosic acid and subsequent degradation reactions."},"publication_date":"2001-06","publication_name":{"en":"Journal of Agricultural and Food Chemistry","ja":"Journal of Agricultural and Food Chemistry"},"volume":"Vol.49","number":"No.11","starting_page":"5560","ending_page":"5565","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/jf010693i"],"issn":["0021-8561"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www2.heterocycles.jp/FMPro?-db=journalred.fp5&-format=/w2/JournalDetail.html&-lay=data&-Token.0=&-Token.3=COM-01-9190&-recid=86&-Script=citation&-find","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0035365031&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62823","label":"url"}],"paper_title":{"en":"A new neoclerodane diterpenoid from Scutellaria hematochlora","ja":"A new neoclerodane diterpenoid from Scutellaria hematochlora"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Tateoka Satomi"},{"name":"Masuda Toshiya"},{"name":"Otsuka Hideaki"},{"name":"Honda Gisho"},{"name":"Takaishi Yoshihisa"},{"name":"Ito Michiho"},{"name":"Khodzhimatov K. Olimjon"},{"name":"Ashurmetov A. Ozodbek"}],"ja":[{"name":"武田 美雄"},{"name":"Tateoka Satomi"},{"name":"増田 俊哉"},{"name":"Otsuka Hideaki"},{"name":"Honda Gisho"},{"name":"高石 喜久"},{"name":"Ito Michiho"},{"name":"Khodzhimatov K. Olimjon"},{"name":"Ashurmetov A. Ozodbek"}]},"description":{"en":"ウズベキスタン産シソ科植物Scutellaria hematochloraからneoclerodan型新ジテルペンを単離しその化学構造を明らかにした.","ja":"ウズベキスタン産シソ科植物Scutellaria hematochloraからneoclerodan型新ジテルペンを単離しその化学構造を明らかにした."},"publication_date":"2001-06","publication_name":{"en":"Heterocycles","ja":"Heterocycles"},"volume":"Vol.55","number":"No.6","starting_page":"1141","ending_page":"1145","languages":["eng"],"referee":true,"identifiers":{"issn":["1881-0942"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://cat.inist.fr/?aModele=afficheN&cpsidt=999802","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11368633","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0034843535&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=63090","label":"url"}],"paper_title":{"en":"Chemical Studies on Antioxidant Mechanism of Curcumin: Analysis of Oxidative Coupling Products from Curcumin and Linoleate","ja":"Chemical Studies on Antioxidant Mechanism of Curcumin: Analysis of Oxidative Coupling Products from Curcumin and Linoleate"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Moekawa Tomomi"},{"name":"Hidaka Kayo"},{"name":"Bando Hiromi"},{"name":"Takeda Yoshio"},{"name":"Yamaguchi Hidemasa"}],"ja":[{"name":"増田 俊哉"},{"name":"Moekawa Tomomi"},{"name":"Hidaka Kayo"},{"name":"Bando Hiromi"},{"name":"武田 美雄"},{"name":"Yamaguchi Hidemasa"}]},"description":{"en":"As a part of a research project on the antioxidant mechanism of natural phenolics in food components, curcumin, a turmeric antioxidant, was investigated in the presence of ethyl linoleate as one of the polyunsaturated lipids. During the antioxidation process, curcumin reacted with four types of linoleate peroxyl radicals. Six reaction products were observed in the reaction and subsequently isolated. Their structures were determined by physical techniques, revealing that they have novel tricyclic structures, including a peroxyl linkage. On the basis of the formation pathway for their chemical structures, an antioxidant mechanism of curcumin in polyunsaturated lipids was proposed, which consisted of an oxidative coupling reaction at the 3'-position of the curcumin with the lipid and a subsequent intramolecular Diels--Alder reaction.","ja":"As a part of a research project on the antioxidant mechanism of natural phenolics in food components, curcumin, a turmeric antioxidant, was investigated in the presence of ethyl linoleate as one of the polyunsaturated lipids. During the antioxidation process, curcumin reacted with four types of linoleate peroxyl radicals. Six reaction products were observed in the reaction and subsequently isolated. Their structures were determined by physical techniques, revealing that they have novel tricyclic structures, including a peroxyl linkage. On the basis of the formation pathway for their chemical structures, an antioxidant mechanism of curcumin in polyunsaturated lipids was proposed, which consisted of an oxidative coupling reaction at the 3'-position of the curcumin with the lipid and a subsequent intramolecular Diels--Alder reaction."},"publication_date":"2001-05","publication_name":{"en":"Journal of Agricultural and Food Chemistry","ja":"Journal of Agricultural and Food Chemistry"},"volume":"Vol.49","number":"No.5","starting_page":"2539","ending_page":"2547","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/jf001442x"],"issn":["0021-8561"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://pubs.acs.org/cgi-bin/abstract.cgi/jnprdf/2001/64/i04/abs/np000211h","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11325229","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124831","label":"url"}],"paper_title":{"en":"Sesquiterpenes and Monoterpenes from the Bark of Inula macrophylla","ja":"Sesquiterpenes and Monoterpenes from the Bark of Inula macrophylla"},"authors":{"en":[{"name":"Su Bao-Ning"},{"name":"Takaishi Yoshihisa"},{"name":"Yabuuchi Tetsuya"},{"name":"Kusumi Takenori"},{"name":"Tori Motoo"},{"name":"Takaoka Shigeru"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Su Bao-Ning"},{"name":"高石 喜久"},{"name":"Yabuuchi Tetsuya"},{"name":"楠見 武徳"},{"name":"Tori Motoo"},{"name":"Takaoka Shigeru"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"Eleven new sesquiterpenes (1--11) and two thymol derivatives (12, 13), along with 12 known sesquiterpenes and monoterpenes, were isolated from the bark of Inula macrophylla. Their structures were determined on the basis of spectral evidence (especially by HREIMS and 2D NMR) as well as chemical transformations. The structure of macrophyllic acid A (1) was confirmed by X-ray analysis, and the absolute configuration of 1 was determined on the basis of the appropriate chemical conversions and the application of a modified Mosher's method.","ja":"Eleven new sesquiterpenes (1--11) and two thymol derivatives (12, 13), along with 12 known sesquiterpenes and monoterpenes, were isolated from the bark of Inula macrophylla. Their structures were determined on the basis of spectral evidence (especially by HREIMS and 2D NMR) as well as chemical transformations. The structure of macrophyllic acid A (1) was confirmed by X-ray analysis, and the absolute configuration of 1 was determined on the basis of the appropriate chemical conversions and the application of a modified Mosher's method."},"publication_date":"2001-04","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.64","number":"No.4","starting_page":"466","ending_page":"471","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np000211h"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1016/S0031-9422(00)00407-6","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11336255","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0035341748&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124832","label":"url"}],"paper_title":{"en":"Terpenoids and γ-pyrone derivatives from Prangos tschimganica","ja":"Terpenoids and γ-pyrone derivatives from Prangos tschimganica"},"authors":{"en":[{"name":"Shikishima Yasuhiro"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Shikishima Yasuhiro"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"The methanol extract of the dried aerial parts of Prangos tschimganica afforded seven monoterpenoids and four gamma-pyrone derivatives. Their structures were established on the basis of chemical and spectroscopic evidence.","ja":"The methanol extract of the dried aerial parts of Prangos tschimganica afforded seven monoterpenoids and four gamma-pyrone derivatives. Their structures were established on the basis of chemical and spectroscopic evidence."},"publication_date":"2001-03","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.57","number":"No.1","starting_page":"135","ending_page":"141","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(00)00407-6"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1016/S0031-9422(00)00370-8","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11249105","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0035961540&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=124833","label":"url"}],"paper_title":{"en":"Phenylbutanoids and stilbene derivatives of Rheum maximowiczii","ja":"Phenylbutanoids and stilbene derivatives of Rheum maximowiczii"},"authors":{"en":[{"name":"Yasuhiro Shikishima"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Yasuhiro Shikishima"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Ito Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"The methanol extract of the dried roots of Rheum maximowiczii afforded four phenylbutanoid and two stilbene derivatives. Their structures were established on the basis of chemical and spectroscopic studies.","ja":"The methanol extract of the dried roots of Rheum maximowiczii afforded four phenylbutanoid and two stilbene derivatives. Their structures were established on the basis of chemical and spectroscopic studies."},"publication_date":"2001-02","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.56","number":"No.4","starting_page":"377","ending_page":"381","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(00)00370-8"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/11297840","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0035048443&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62821","label":"url"}],"paper_title":{"en":"Traditional medicine in Turkey X. Folk medicine in Central Anatolia","ja":"Traditional medicine in Turkey X. Folk medicine in Central Anatolia"},"authors":{"en":[{"name":"Sezik Ekrem"},{"name":"Yesilada Erdem"},{"name":"Honda Gisho"},{"name":"Takaishi Yoshihisa"},{"name":"Takeda Yoshio"},{"name":"Tanaka Toshihiro"}],"ja":[{"name":"Sezik Ekrem"},{"name":"Yesilada Erdem"},{"name":"Honda Gisho"},{"name":"高石 喜久"},{"name":"武田 美雄"},{"name":"Tanaka Toshihiro"}]},"description":{"en":"Traditional medicine used in Central Anatolia; Ankara, Kayseri, Niğde and south-eastern parts of Karaman and Konya provinces have been studied. Two hundred and ninety one folk remedies obtained from 103 plant species belonging to 40 families and 4 animal species are reported with their vernacular names, parts used, methods of preparing remedies and therapeutic usage.","ja":"トルコ共和国中央Anatolia地方の伝統薬について現地調査し,その起源植物名,伝統的な用法などについて報告した."},"publication_date":"2001-01","publication_name":{"en":"Journal of Ethnopharmacology","ja":"Journal of Ethnopharmacology"},"volume":"Vol.75","number":"No.2-3","starting_page":"95","ending_page":"115","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0378-8741(00)00399-8"],"issn":["0378-8741"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1016/S0031-9422(00)00197-7","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10975507","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=127139","label":"url"}],"paper_title":{"en":"Sesquiterpenoids from Ferula kuhistanica","ja":"Sesquiterpenoids from Ferula kuhistanica"},"authors":{"en":[{"name":"Chen Bei"},{"name":"Teranishi Rie"},{"name":"Kawazoe Kazuyoshi"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"Itoh Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"}],"ja":[{"name":"Chen Bei"},{"name":"Teranishi Rie"},{"name":"川添 和義"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"Itoh Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"}]},"description":{"en":"Methanol extracts of the air-dried roots and stems of Ferula kuhistanica afforded seven daucane-type sesquiterpenes, called kuhistanicaol A-G, together with 13 known daucane esters. Their structures were established on the basis of spectroscopic evidence and the results of chemical reactions.","ja":"Methanol extracts of the air-dried roots and stems of Ferula kuhistanica afforded seven daucane-type sesquiterpenes, called kuhistanicaol A-G, together with 13 known daucane esters. Their structures were established on the basis of spectroscopic evidence and the results of chemical reactions."},"publication_date":"2000-08","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.54","number":"No.7","starting_page":"717","ending_page":"722","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(00)00197-7"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62838","label":"url"}],"paper_title":{"en":"Labdane diterpenoids from Marrubium globosum ssp. globosum","ja":"Labdane diterpenoids from Marrubium globosum ssp. globosum"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Yanagihara Kazumi"},{"name":"Masuda Toshiya"},{"name":"Otsuka Hideaki"},{"name":"Honda Gisho"},{"name":"Takaishi Yoshihisa"},{"name":"Sezik Ekrem"},{"name":"Yesilada Erdem"}],"ja":[{"name":"武田 美雄"},{"name":"Yanagihara Kazumi"},{"name":"増田 俊哉"},{"name":"Otsuka Hideaki"},{"name":"Honda Gisho"},{"name":"高石 喜久"},{"name":"Sezik Ekrem"},{"name":"Yesilada Erdem"}]},"description":{"en":"トルコ産薬用植物Marrubium globosum ssp. globosumのジテルペン成分について検索し,labdane 骨格を有する新微量成分を単離しその化学構造を明らかにした.","ja":"トルコ産薬用植物Marrubium globosum ssp. globosumのジテルペン成分について検索し,labdane 骨格を有する新微量成分を単離しその化学構造を明らかにした."},"publication_date":"2000-08","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.48","number":"No.8","starting_page":"1234","ending_page":"1235","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0034719698&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=63098","label":"url"}],"paper_title":{"en":"A Novel Radical Terminated Compound Produced in the Antioxidation Process of Curcumin against Oxidation of a Fatty Acid Ester","ja":"A Novel Radical Terminated Compound Produced in the Antioxidation Process of Curcumin against Oxidation of a Fatty Acid Ester"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Bando Hiromi"},{"name":"Maekawa Tomomi"},{"name":"Takeda Yoshio"},{"name":"Yamaguchi Hidemasa"}],"ja":[{"name":"増田 俊哉"},{"name":"Bando Hiromi"},{"name":"Maekawa Tomomi"},{"name":"武田 美雄"},{"name":"Yamaguchi Hidemasa"}]},"publication_date":"2000-07","publication_name":{"en":"Tetrahedron Letters","ja":"Tetrahedron Letters"},"volume":"Vol.41","number":"No.13","starting_page":"2157","ending_page":"2160","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0040-4039(00)00123-4"],"issn":["0040-4039"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62841","label":"url"}],"paper_title":{"en":"Isolation of lignan glucoside and neolignan sulfate from the leaves of Glochidion zeylanicum (Gaertn) A. Juss.","ja":"Isolation of lignan glucoside and neolignan sulfate from the leaves of Glochidion zeylanicum (Gaertn) A. Juss."},"authors":{"en":[{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"武田 美雄"}]},"description":{"en":"沖縄産カキバカンコノキのリグナン関連物質を検索し,2種の新化合物を4種の既知化合物と共に単離氏,新化合物についてはその化学構造を明らかにした.","ja":"沖縄産カキバカンコノキのリグナン関連物質を検索し,2種の新化合物を4種の既知化合物と共に単離氏,新化合物についてはその化学構造を明らかにした."},"publication_date":"2000-07","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.48","number":"No.7","starting_page":"1084","ending_page":"1086","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10820046","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0034071115&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=63096","label":"url"}],"paper_title":{"en":"Isolation and Structure Determination of New Antioxidative Ferulic Acid Glucoside Esters from the Rhizomes of Alpinia speciosa, a Zingiberaceae Plant Used in Okinawan Food Culture","ja":"Isolation and Structure Determination of New Antioxidative Ferulic Acid Glucoside Esters from the Rhizomes of Alpinia speciosa, a Zingiberaceae Plant Used in Okinawan Food Culture"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Mizuguchi Shinichi"},{"name":"Tanaka Tomochika"},{"name":"Iritani Kumiko"},{"name":"Takeda Yoshio"},{"name":"Yonemori Sigetomo"}],"ja":[{"name":"増田 俊哉"},{"name":"Mizuguchi Shinichi"},{"name":"Tanaka Tomochika"},{"name":"Iritani Kumiko"},{"name":"武田 美雄"},{"name":"Yonemori Sigetomo"}]},"description":{"en":"An assay-guided isolation gave three antioxidants including two newly identified compounds from the rhizomes of Alpinia speciosa, which is used as an important plant in the food culture of the Okinawa area of Japan. Spectroscopic analysis of the two new compounds revealed them to be new glucoside esters of ferulic acid. The antioxidant activity of the esters was measured using two different methods. Both compounds showed greater activity than that of Trolox in the TLC method; however, one of the compounds showed weaker inhibitory activity than that of Trolox and epicatechin against AMVN-induced methyl linoleate oxidation.","ja":"An assay-guided isolation gave three antioxidants including two newly identified compounds from the rhizomes of Alpinia speciosa, which is used as an important plant in the food culture of the Okinawa area of Japan. Spectroscopic analysis of the two new compounds revealed them to be new glucoside esters of ferulic acid. The antioxidant activity of the esters was measured using two different methods. Both compounds showed greater activity than that of Trolox in the TLC method; however, one of the compounds showed weaker inhibitory activity than that of Trolox and epicatechin against AMVN-induced methyl linoleate oxidation."},"publication_date":"2000-05","publication_name":{"en":"Journal of Agricultural and Food Chemistry","ja":"Journal of Agricultural and Food Chemistry"},"volume":"Vol.48","number":"No.5","starting_page":"1479","ending_page":"1484","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/jf991294e"],"issn":["0021-8561"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62848","label":"url"}],"paper_title":{"en":"A new mwgastigmane and a new tetraketide from leaves of Euscaphis japonica","ja":"A new mwgastigmane and a new tetraketide from leaves of Euscaphis japonica"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Okada Yoshihiro"},{"name":"Masuda Toshiya"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"Yu Qian"},{"name":"Otsuka Hideaki"}],"ja":[{"name":"武田 美雄"},{"name":"Okada Yoshihiro"},{"name":"増田 俊哉"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"Yu Qian"},{"name":"Otsuka Hideaki"}]},"description":{"en":"沖縄産ミツバウツギ科植物ゴンズイ葉部より新メガスチグマンおよびテトラケチドを単離しその化学構造を明らかにした.","ja":"沖縄産ミツバウツギ科植物ゴンズイ葉部より新メガスチグマンおよびテトラケチドを単離しその化学構造を明らかにした."},"publication_date":"2000-05","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.48","number":"No.5","starting_page":"752","ending_page":"754","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1021/np9904298","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10785430","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=127140","label":"url"}],"paper_title":{"en":"Sesquiterpene Phenylpropanoid and Sesquiterpene Chromone Derivatives from Ferula pallida","ja":"Sesquiterpene Phenylpropanoid and Sesquiterpene Chromone Derivatives from Ferula pallida"},"authors":{"en":[{"name":"Su Bao-Ning"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Su Bao-Ning"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"Four novel compounds-two sesquiterpene phenylpropanoid derivatives, pallidones G (1) and H (2), and two sesquiterpene chromone derivatives, pallidones I (3) and J (4)-have been isolated from the roots of Ferula pallida. Their structures were determined on the basis of NMR and HREIMS evidence.","ja":"Four novel compounds-two sesquiterpene phenylpropanoid derivatives, pallidones G (1) and H (2), and two sesquiterpene chromone derivatives, pallidones I (3) and J (4)-have been isolated from the roots of Ferula pallida. Their structures were determined on the basis of NMR and HREIMS evidence."},"publication_date":"2000-04","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.63","number":"No.4","starting_page":"520","ending_page":"522","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np9904298"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10820806","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0034716834&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62891","label":"url"}],"paper_title":{"en":"Phlorigidosides A-C, iridoid glucosides from Phlomis rigida","ja":"Phlorigidosides A-C, iridoid glucosides from Phlomis rigida"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Matsumura Hiroyuki"},{"name":"Masuda Toshiya"},{"name":"Honda Gisho"},{"name":"Otsuka Hideaki"},{"name":"Takaishi Yoshihisa"},{"name":"Sezikand Ekrem"},{"name":"Yesilada Erdem"}],"ja":[{"name":"武田 美雄"},{"name":"Matsumura Hiroyuki"},{"name":"増田 俊哉"},{"name":"Honda Gisho"},{"name":"Otsuka Hideaki"},{"name":"高石 喜久"},{"name":"Sezikand Ekrem"},{"name":"Yesilada Erdem"}]},"description":{"en":"From the aerial parts of Phlomis rigida, three iridoid glucosides, phlorigidoside A (2-O-acetyllamiridoside), B (8-O-acetyl-6-beta-hydroxyipolamide) and C (5-deoxysesamoside), were isolated together with the known iridoid glucosides, shanzhiside methyl ester, 8-O-acetylshanzhiside methyl ester, deoxypulcheloside I, lamiridoside, and 6-beta-hydroxyipolamide. The structures of the new compounds were elucidated based on spectral and chemical evidence.","ja":"トルコ産Phlomis rigida地上部の配糖体成分を検索し,5種の既知物質とともに3種の新イリドイド配糖体を単離しその化学構造を明らかにした."},"publication_date":"2000-04","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.53","number":"No.8","starting_page":"931","ending_page":"935","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(99)00431-8"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62879","label":"url"}],"paper_title":{"en":"Megastigmane, benzyl and phenethyl alcohol glycosides, and 4,4`-dimethoxytruxinic acid catalpol diester from the leaves of Premna subscandens","ja":"Megastigmane, benzyl and phenethyl alcohol glycosides, and 4,4`-dimethoxytruxinic acid catalpol diester from the leaves of Premna subscandens"},"authors":{"en":[{"name":"Sudo Hirokazu"},{"name":"Ide Toshinori"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Sudo Hirokazu"},{"name":"Ide Toshinori"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"武田 美雄"}]},"description":{"en":"沖縄産クマツズラ科植物Premna subscandens葉部より4種の新化合物を単離し,その化学構造を明らかにした.","ja":"沖縄産クマツズラ科植物Premna subscandens葉部より4種の新化合物を単離し,その化学構造を明らかにした."},"publication_date":"2000-04","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.48","number":"No.4","starting_page":"542","ending_page":"546","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62857","label":"url"}],"paper_title":{"en":"Glochidionolactone A-F: butenolide glucosides from leaves of Glochidion zeylanicum","ja":"Glochidionolactone A-F: butenolide glucosides from leaves of Glochidion zeylanicum"},"authors":{"en":[{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"Takeda Yoshio"},{"name":"Bando Masahiko"},{"name":"Kido Masaru"}],"ja":[{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"武田 美雄"},{"name":"Bando Masahiko"},{"name":"Kido Masaru"}]},"description":{"en":"沖縄産トウダイグサ科植物カキバカンコノキ葉部から6種の新butenolide配糖体を単離し,その化学構造をX線結晶解析の手法も含め明らかにした.","ja":"沖縄産トウダイグサ科植物カキバカンコノキ葉部から6種の新butenolide配糖体を単離し,その化学構造をX線結晶解析の手法も含め明らかにした."},"publication_date":"2000-04","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.48","number":"No.4","starting_page":"547","ending_page":"551","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1016/S0031-9422(99)00554-3","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10746882","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=127147","label":"url"}],"paper_title":{"en":"Coumarins and bicoumarin from Ferula sumbul: anti-HIV activity and inhibition of cytokine release","ja":"Coumarins and bicoumarin from Ferula sumbul: anti-HIV activity and inhibition of cytokine release"},"authors":{"en":[{"name":"Zhou Ping"},{"name":"Takaishi Yoshihisa"},{"name":"Duan Hongquan"},{"name":"Chen Bei"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"Takeda Yoshio"},{"name":"Olimjon K. Kodzhimatov"},{"name":"Lee Kuo-Hsing"}],"ja":[{"name":"Zhou Ping"},{"name":"高石 喜久"},{"name":"Duan Hongquan"},{"name":"Chen Bei"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"武田 美雄"},{"name":"Olimjon K. Kodzhimatov"},{"name":"Lee Kuo-Hsing"}]},"description":{"en":"The methanol extract of the dried roots of Ferula sumbul afforded two furanocoumarin esters, fesumtuorin A, B, one bicoumarin, fesumtuorin C, five spirobicoumarins, fesumtuorin D, E, F, G and H, along with nineteen known coumarins. Their structures were established on the basis of spectroscopic studies. Some of the isolated compounds showed anti-HIV activity and very weak inhibition of cytokine release.","ja":"The methanol extract of the dried roots of Ferula sumbul afforded two furanocoumarin esters, fesumtuorin A, B, one bicoumarin, fesumtuorin C, five spirobicoumarins, fesumtuorin D, E, F, G and H, along with nineteen known coumarins. Their structures were established on the basis of spectroscopic studies. Some of the isolated compounds showed anti-HIV activity and very weak inhibition of cytokine release."},"publication_date":"2000-03-08","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.53","number":"No.6","starting_page":"689","ending_page":"697","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(99)00554-3"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1021/np990338a","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10757719","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=127149","label":"url"}],"paper_title":{"en":"Prenylated Benzoic Acid Derivatives from Ferula kuhistanica","ja":"Prenylated Benzoic Acid Derivatives from Ferula kuhistanica"},"authors":{"en":[{"name":"Chen Bei"},{"name":"Kawazoe Kazuyoshi"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Chen Bei"},{"name":"川添 和義"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"Four new prenylated benzoic acid derivatives, kuhistanols A-D (1-4), along with one known compound, 3-farnesyl-p-hydroxybenzoic acid (5), have been isolated from the roots of the Uzbekistan medicinal plant, Ferula kuhistanica. Their structures were established on the basis of chemical and spectral evidence. Compound 4 showed a significant inhibitory effect on cytokine production in lipopolysaccharide-stimulated human peripheral mononuclear cells.","ja":"Four new prenylated benzoic acid derivatives, kuhistanols A-D (1-4), along with one known compound, 3-farnesyl-p-hydroxybenzoic acid (5), have been isolated from the roots of the Uzbekistan medicinal plant, Ferula kuhistanica. Their structures were established on the basis of chemical and spectral evidence. Compound 4 showed a significant inhibitory effect on cytokine production in lipopolysaccharide-stimulated human peripheral mononuclear cells."},"publication_date":"2000-03","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.63","number":"No.3","starting_page":"362","ending_page":"365","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np990338a"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1016/S0040-4039(99)02321-7","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=127151","label":"url"}],"paper_title":{"en":"Macrophyllidimers A and B, two novel sesquiterpene dimers from the bark of Inula macrophylla","ja":"Macrophyllidimers A and B, two novel sesquiterpene dimers from the bark of Inula macrophylla"},"authors":{"en":[{"name":"Su Bao-Ning"},{"name":"Takaishi Yoshihisa"},{"name":"Tori Motoo"},{"name":"Takaoka Shigeru"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Su Bao-Ning"},{"name":"高石 喜久"},{"name":"Tori Motoo"},{"name":"Takaoka Shigeru"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"publication_date":"2000-02-26","publication_name":{"en":"Tetrahedron Letters","ja":"Tetrahedron Letters"},"volume":"Vol.41","number":"No.9","starting_page":"1475","ending_page":"1479","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0040-4039(99)02321-7"],"issn":["0040-4039"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1021/ol990401n","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10814359","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0034707972&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=127152","label":"url"}],"paper_title":{"en":"Macrophyllols A and B, Two Unusual Novel Sesquiterpene and Monoterpene Dimers from the Bark of Inula macrophylla","ja":"Macrophyllols A and B, Two Unusual Novel Sesquiterpene and Monoterpene Dimers from the Bark of Inula macrophylla"},"authors":{"en":[{"name":"Su Bao-Ning"},{"name":"Takaishi Yoshihisa"},{"name":"Tori Motoo"},{"name":"Takaoka Shigeru"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Su Bao-Ning"},{"name":"高石 喜久"},{"name":"Tori Motoo"},{"name":"Takaoka Shigeru"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"[structure: see text] Two novel sesquiterpene and monoterpene dimers, macrophyllols A (1) and B (2), were isolated from the bark of Inula macrophylla. Their structures were determined on the basis of spectral evidence (especially HREIMS and 2D NMR) as well as chemical transformation. The structure of macrophyllol A (1) was confirmed by X-ray analysis. The possible biosynthetic pathways of macrophyllols A (1) and B (2) are discussed.","ja":"[structure: see text] Two novel sesquiterpene and monoterpene dimers, macrophyllols A (1) and B (2), were isolated from the bark of Inula macrophylla. Their structures were determined on the basis of spectral evidence (especially HREIMS and 2D NMR) as well as chemical transformation. The structure of macrophyllol A (1) was confirmed by X-ray analysis. The possible biosynthetic pathways of macrophyllols A (1) and B (2) are discussed."},"publication_date":"2000-02-24","publication_name":{"en":"Organic Letters","ja":"Organic Letters"},"volume":"Vol.2","number":"No.4","starting_page":"493","ending_page":"496","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/ol990401n"],"issn":["1523-7060"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10731029","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0034624479&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62896","label":"url"}],"paper_title":{"en":"Iridoid glycosides from Lonicera quinquelocularis","ja":"Iridoid glycosides from Lonicera quinquelocularis"},"authors":{"en":[{"name":"Kumar S."},{"name":"Sati O.P."},{"name":"Semwal V.D."},{"name":"Nautial M."},{"name":"Takeda Yoshio"}],"ja":[{"name":"Kumar S."},{"name":"Sati O.P."},{"name":"Semwal V.D."},{"name":"Nautial M."},{"name":"武田 美雄"}]},"description":{"en":"A new iridoid glycoside 6'-O-beta-apiofuranosylsweroside was isolated from the ethanolic extract of the roots of Lonicera quinquelocularis along with the known compounds loganin and sweroside.","ja":"インドのヒマラヤ地方に分布するスイカズラ科植物Loncera quinquelocularisの配糖体成分を検索し既知のloganin, swerosideの他に,新配糖体を単離し,その化学構造を明らかにした."},"publication_date":"2000-02-09","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.53","number":"No.4","starting_page":"499","ending_page":"501","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(99)00426-4"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/110008732013/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520572358781818880/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0034109471&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62900","label":"url"}],"paper_title":{"en":"A new phenylpropanoid-glycerol conjugate from Helitiera littoralis Dryand","ja":"A new phenylpropanoid-glycerol conjugate from Helitiera littoralis Dryand"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Shimidzu Hideko"},{"name":"Masuda Toshiya"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"Shinzato Takakazu"},{"name":"Otsuka Hideaki"}],"ja":[{"name":"武田 美雄"},{"name":"Shimidzu Hideko"},{"name":"増田 俊哉"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"Shinzato Takakazu"},{"name":"Otsuka Hideaki"}]},"description":{"en":"From the leaves of Helitiera littoralis, a new phenylpropanoid-glycerolconjugate was isolated together with known compounds, isolariciresinol-3a-O-β-D-glucoside, (Z)-3-hexenyl β-D-glucoside, methyl [β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl]-salicylate, afzelin, astragalin, quercitrin and tribuloside. The structure of the new compound was elucidated as 2-O-[4'-(3\"-hydroxypropyl)-2',5'-dimethoxyphenyl]-1-O-β-D-glucopyranosylglycerol by spectral and chemical evidence.","ja":"沖縄産サキシマスホウノキ葉部の成分を検索し,7種の既知化合物と共に新phenylpropanoid-glycerol conjugateを単離し,その化学構造を明らかにした."},"publication_date":"2000-01","publication_name":{"en":"Natural Medicines","ja":"Natural Medicines"},"volume":"Vol.54","number":"No.1","starting_page":"22","ending_page":"25","languages":["eng"],"referee":true,"identifiers":{"issn":["1340-3443"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10678355","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62886","label":"url"}],"paper_title":{"en":"Potentiation of ganciclovir toxity in herpes simplex virus thymidine kinase/ganciclovir administration system by ponicidin","ja":"Potentiation of ganciclovir toxity in herpes simplex virus thymidine kinase/ganciclovir administration system by ponicidin"},"authors":{"en":[{"name":"Hayashi Kyoko"},{"name":"Hayashi Toshimitsu"},{"name":"Sun Han-dong"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Hayashi Kyoko"},{"name":"Hayashi Toshimitsu"},{"name":"Sun Han-dong"},{"name":"武田 美雄"}]},"description":{"en":"シソ科植物から単離されたジテルペン,ponicidinが抗ウイルス剤ACVおよびGCVの作用をherpes simplex virusのthimidine kinaseを活性化することにより相乗的に強めることをin vitroの実験結果より明らかにした.","ja":"シソ科植物から単離されたジテルペン,ponicidinが抗ウイルス剤ACVおよびGCVの作用をherpes simplex virusのthimidine kinaseを活性化することにより相乗的に強めることをin vitroの実験結果より明らかにした."},"publication_date":"2000-01","publication_name":{"en":"Cancer Gene Therapy","ja":"Cancer Gene Therapy"},"volume":"Vol.7","number":"No.1","starting_page":"45","ending_page":"52","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1038/sj.cgt.7700084"],"issn":["0929-1903"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62861","label":"url"}],"paper_title":{"en":"Oleanene palmitate from Ximenia americana","ja":"Oleanene palmitate from Ximenia americana"},"authors":{"en":[{"name":"Fatope Oladeji Majekodunmi"},{"name":"Adoum A Oumar"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Fatope Oladeji Majekodunmi"},{"name":"Adoum A Oumar"},{"name":"武田 美雄"}]},"description":{"en":"Ximenia americana地下部より3-olean-12-enyl palmitateの単離と同定について報告.","ja":"Ximenia americana地下部より3-olean-12-enyl palmitateの単離と同定について報告."},"publication_date":"2000-01","publication_name":{"en":"Pharmaceutical Biology","ja":"Pharmaceutical Biology"},"volume":"Vol.38","number":"No.5","starting_page":"391","ending_page":"393","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1076/phbi.38.5.391.5972"],"issn":["1388-0209"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62843","label":"url"}],"paper_title":{"en":"C18 acetylenic fatty acids of Ximenia americana","ja":"C18 acetylenic fatty acids of Ximenia americana"},"authors":{"en":[{"name":"Fatope Oladeji Majekodunmi"},{"name":"Adoum A Oumar"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Fatope Oladeji Majekodunmi"},{"name":"Adoum A Oumar"},{"name":"武田 美雄"}]},"description":{"en":"Ximenia americana地下部の成分をbrine shrimp lethality testなどの生物検定法に従い分画し,活性物質として2種のC18アセチレン結合を含む脂肪酸を単離しその化学構造を明らかにした.","ja":"Ximenia americana地下部の成分をbrine shrimp lethality testなどの生物検定法に従い分画し,活性物質として2種のC18アセチレン結合を含む脂肪酸を単離しその化学構造を明らかにした."},"publication_date":"2000-01","publication_name":{"en":"Journal of Agricultural and Food Chemistry","ja":"Journal of Agricultural and Food Chemistry"},"volume":"Vol.48","number":"No.5","starting_page":"1872","ending_page":"1874","languages":["eng"],"referee":true,"identifiers":{"issn":["0021-8561"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0034070548&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62832","label":"url"}],"paper_title":{"en":"Quality evaluation of plant dye Henna with glycosides","ja":"植物染料hennaの配糖体と品質について"},"authors":{"en":[{"name":"川村 智子"},{"name":"久田 陽一"},{"name":"奥田 和代"},{"name":"野呂 征男"},{"name":"Takeda Yoshio"},{"name":"田中 俊弘"}],"ja":[{"name":"川村 智子"},{"name":"久田 陽一"},{"name":"奥田 和代"},{"name":"野呂 征男"},{"name":"武田 美雄"},{"name":"田中 俊弘"}]},"description":{"en":"植物染料Henna(Lawsonia inermisの葉)の品質評価法として指標物質として従来用いられていたlawsone(この化合物は抽出過程で生じた人口産物と考えられる)に変え,2種の配糖体を指標物質とした評価法を確立すると共に,種々の市場品についてその品質を評価した.","ja":"植物染料Henna(Lawsonia inermisの葉)の品質評価法として指標物質として従来用いられていたlawsone(この化合物は抽出過程で生じた人口産物と考えられる)に変え,2種の配糖体を指標物質とした評価法を確立すると共に,種々の市場品についてその品質を評価した."},"publication_date":"2000-01","publication_name":{"en":"Natural Medicines","ja":"Natural Medicines"},"volume":"Vol.54","number":"No.2","starting_page":"86","ending_page":"89","languages":["jpn"],"referee":true,"identifiers":{"issn":["1340-3443"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://ci.nii.ac.jp/naid/110008732168/","label":"url"},{"@id":"https://cir.nii.ac.jp/crid/1520290882285300352/","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0036105399&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62818","label":"url"}],"paper_title":{"en":"New sesquiterpene glucosides from Crepidiastrum lanceolatum","ja":"New sesquiterpene glucosides from Crepidiastrum lanceolatum"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Morikawa Hiroyuki"},{"name":"Masuda Toshiya"},{"name":"Hirata Eiji"},{"name":"Shinnzato Takakazu"},{"name":"Otsuka Hideaki"}],"ja":[{"name":"武田 美雄"},{"name":"Morikawa Hiroyuki"},{"name":"増田 俊哉"},{"name":"Hirata Eiji"},{"name":"Shinnzato Takakazu"},{"name":"Otsuka Hideaki"}]},"description":{"en":"From the underground parts of Crepidiastrum lanceolatum, two new sesquiterpene glucoside p-hydroxyphenylacetic acid esters, crepidialanceosides A and B, were isolated together with two known compounds, youngiaside D and sonchuside A. The structures of new compounds were elucidated based on spectral analyses and chemical evidence.","ja":"沖縄地方で民間薬,食用として用いられているホソバワダン地下部の配糖体成分を検索しcrepidialanceosides A, Bの2種の新セスキテルペン配糖体を単離し,その化学構造を明らかにした."},"publication_date":"2000-01","publication_name":{"en":"Natural Medicines","ja":"Natural Medicines"},"volume":"Vol.56","number":"No.2","starting_page":"51","ending_page":"54","languages":["eng"],"referee":true,"identifiers":{"issn":["1340-3443"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://dx.doi.org/10.1021/np990262i","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/10785409","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=127144","label":"url"}],"paper_title":{"en":"Sesquiterpene Coumarins and Related Derivatives from Ferula pallida","ja":"Sesquiterpene Coumarins and Related Derivatives from Ferula pallida"},"authors":{"en":[{"name":"Su Bao-Ning"},{"name":"Takaishi Yoshihisa"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"Takeda Yoshio"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}],"ja":[{"name":"Su Bao-Ning"},{"name":"高石 喜久"},{"name":"Honda Gisho"},{"name":"Itoh Michiho"},{"name":"武田 美雄"},{"name":"Kodzhimatov K. Olimjon"},{"name":"Ashurmetov Ozodbek"}]},"description":{"en":"Six new compounds-two sesquiterpene coumarins, pallidones A and B (1, 2), and four related derivatives, pallidones C-F (3-6), as well as two known sesquiterpene coumarins, feselol (7) and conferol (8), have been isolated from the EtOAc extracts of the roots of Ferula pallida. All structures of these compounds were determined on the basis of spectral evidence, especially 2D NMR ((1)H-(1)H COSY, HSQC, HMBC, and NOESY) and HRMS. The possible biosynthetic pathway of pallidones C-F (3-6) is discussed.","ja":"Six new compounds-two sesquiterpene coumarins, pallidones A and B (1, 2), and four related derivatives, pallidones C-F (3-6), as well as two known sesquiterpene coumarins, feselol (7) and conferol (8), have been isolated from the EtOAc extracts of the roots of Ferula pallida. All structures of these compounds were determined on the basis of spectral evidence, especially 2D NMR ((1)H-(1)H COSY, HSQC, HMBC, and NOESY) and HRMS. The possible biosynthetic pathway of pallidones C-F (3-6) is discussed."},"publication_date":"2000","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.63","number":"No.4","starting_page":"436","ending_page":"440","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np990262i"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62949","label":"url"}],"paper_title":{"en":"Hydroquinone diglycoside acyl esters from leaves of Myrsine sequinii","ja":"Hydroquinone diglycoside acyl esters from leaves of Myrsine sequinii"},"authors":{"en":[{"name":"Zhong Xi-Ning"},{"name":"Otsuka Hideaki"},{"name":"Ide Toshinori"},{"name":"Hirata Eiji"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Zhong Xi-Ning"},{"name":"Otsuka Hideaki"},{"name":"Ide Toshinori"},{"name":"Hirata Eiji"},{"name":"武田 美雄"}]},"description":{"en":"沖縄産Myrsine seguinii 葉部の配糖体成分を検索し,5種の新フェノール性配糖体seguinosides G-Kを単離しその化学構造を明らかにした.","ja":"沖縄産Myrsine seguinii 葉部の配糖体成分を検索し,5種の新フェノール性配糖体seguinosides G-Kを単離しその化学構造を明らかにした."},"publication_date":"1999-11","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.52","number":"No.5","starting_page":"923","ending_page":"927","languages":["eng"],"referee":true,"identifiers":{"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62957","label":"url"}],"paper_title":{"en":"Nepetaracemosides A and B: iridoid glucosides from Nepeta racemosa","ja":"Nepetaracemosides A and B: iridoid glucosides from Nepeta racemosa"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Kiba Yuuko"},{"name":"Masuda Toshiya"},{"name":"Otsuka Hideaki"},{"name":"Honda Gisho"},{"name":"Tagawa Motoko"},{"name":"Sezik Ekrem"},{"name":"Yesilada Erdem"}],"ja":[{"name":"武田 美雄"},{"name":"Kiba Yuuko"},{"name":"増田 俊哉"},{"name":"Otsuka Hideaki"},{"name":"Honda Gisho"},{"name":"Tagawa Motoko"},{"name":"Sezik Ekrem"},{"name":"Yesilada Erdem"}]},"description":{"en":"ウズベキスタン産Nepeta rasemosa地上部の配糖体成分を検索し,nepetalactone,dehydronepetalactoneと密接に関連したイリドイド配糖体,nepetaracemosides A, Bを単離し,その化学構造を明らかにした.","ja":"ウズベキスタン産Nepeta rasemosa地上部の配糖体成分を検索し,nepetalactone,dehydronepetalactoneと密接に関連したイリドイド配糖体,nepetaracemosides A, Bを単離し,その化学構造を明らかにした."},"publication_date":"1999-10","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.47","number":"No.10","starting_page":"1433","ending_page":"1435","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1248/cpb.47.1433"],"issn":["1347-5223"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://cpb.pharm.or.jp/abst/199909/ac47091338.html","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62967","label":"url"}],"paper_title":{"en":"Secoiridoid glycosides from Gentiana olivierii","ja":"Secoiridoid glycosides from Gentiana olivierii"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Masuda Toshiya"},{"name":"Honda Gisho"},{"name":"Takaishi Yoshihisa"},{"name":"Ito Michiho"},{"name":"Ashurmetov A. Ozodebek"},{"name":"Khodzhimatov K. Olimjon"},{"name":"Otsuka Hideaki"}],"ja":[{"name":"武田 美雄"},{"name":"増田 俊哉"},{"name":"Honda Gisho"},{"name":"高石 喜久"},{"name":"Ito Michiho"},{"name":"Ashurmetov A. Ozodebek"},{"name":"Khodzhimatov K. Olimjon"},{"name":"Otsuka Hideaki"}]},"description":{"en":"ウズベキスタン産薬用植物Gentiana olivieri全草の成分について検討を加え,7種の既知セコイリドイド配糖体を同定すると共に,3種の新苦味セコイリドイド配糖体を単離しその化学構造を明らかにした.","ja":"ウズベキスタン産薬用植物Gentiana olivieri全草の成分について検討を加え,7種の既知セコイリドイド配糖体を同定すると共に,3種の新苦味セコイリドイド配糖体を単離しその化学構造を明らかにした."},"publication_date":"1999-09","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.47","number":"No.9","starting_page":"1338","ending_page":"1340","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62963","label":"url"}],"paper_title":{"en":"A collagen network foreffector from leaves of Premna subscandensmation","ja":"A collagen network foreffector from leaves of Premna subscandensmation"},"authors":{"en":[{"name":"Sudo Hirokazu"},{"name":"Kijima Kaori"},{"name":"Otsuka Hideaki"},{"name":"Ide Toshinori"},{"name":"Hirata Eiji"},{"name":"Takeda Yoshio"},{"name":"Isaji Masayuki"},{"name":"Kurashina Yoshikazu"}],"ja":[{"name":"Sudo Hirokazu"},{"name":"Kijima Kaori"},{"name":"Otsuka Hideaki"},{"name":"Ide Toshinori"},{"name":"Hirata Eiji"},{"name":"武田 美雄"},{"name":"Isaji Masayuki"},{"name":"Kurashina Yoshikazu"}]},"description":{"en":"M細胞は長期間in vitroで培養するとコラーゲン繊維ネットワークを形成するが,それに影響を及ぼす天然物検索の過程でPremna subscandensより活性物質としてacteosideを同定した.","ja":"M細胞は長期間in vitroで培養するとコラーゲン繊維ネットワークを形成するが,それに影響を及ぼす天然物検索の過程でPremna subscandensより活性物質としてacteosideを同定した."},"publication_date":"1999-09","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.47","number":"No.9","starting_page":"1341","ending_page":"1343","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0032428093&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=76001","label":"url"}],"paper_title":{"en":"Euscapholide and its Glucoside from Leaves of Euscaphis japanica","ja":"Euscapholide and its Glucoside from Leaves of Euscaphis japanica"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Okada Yoshihiro"},{"name":"Masuda Toshiya"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"Otsuka Hideaki"}],"ja":[{"name":"武田 美雄"},{"name":"Okada Yoshihiro"},{"name":"増田 俊哉"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"Otsuka Hideaki"}]},"description":{"en":"沖縄産ミツバウツギ科植物ゴンズイ葉部から新テトラケチドおよびその配糖体を単離し,その化学構造を明らかにした.","ja":"沖縄産ミツバウツギ科植物ゴンズイ葉部から新テトラケチドおよびその配糖体を単離し,その化学構造を明らかにした."},"publication_date":"1999-08","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.49","number":"No.8","starting_page":"2565","ending_page":"2568","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(98)00193-9"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0033385006&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62944","label":"url"}],"paper_title":{"en":"Premnaodorosides D-G: Acyclic monoterpene diols iridoid glucoside diester from leaves of Premna subscandens","ja":"Premnaodorosides D-G: Acyclic monoterpene diols iridoid glucoside diester from leaves of Premna subscandens"},"authors":{"en":[{"name":"Sudo Hirokazu"},{"name":"Takushi Anki"},{"name":"Hirata Eiji"},{"name":"Ide Toshinori"},{"name":"Otsuka Hideaki"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Sudo Hirokazu"},{"name":"Takushi Anki"},{"name":"Hirata Eiji"},{"name":"Ide Toshinori"},{"name":"Otsuka Hideaki"},{"name":"武田 美雄"}]},"description":{"en":"石垣島産Premna subscandens葉部より4しゅの新イリドイド配糖体premnaodorosides D-Gを単離し,その化学構造を明らかにした.","ja":"石垣島産Premna subscandens葉部より4しゅの新イリドイド配糖体premnaodorosides D-Gを単離し,その化学構造を明らかにした."},"publication_date":"1999-08","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.52","number":"No.8","starting_page":"1495","ending_page":"1499","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1016/S0031-9422(99)00218-6"],"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
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{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=63100","label":"url"}],"paper_title":{"en":"Evaluation of Antioxidant Activity of Environmental Plants: Activity of the Leaf Extracts from Seashore Plants","ja":"Evaluation of Antioxidant Activity of Environmental Plants: Activity of the Leaf Extracts from Seashore Plants"},"authors":{"en":[{"name":"Masuda Toshiya"},{"name":"Yonemori Shigetomo"},{"name":"Oyama Yasuo"},{"name":"Takeda Yoshio"},{"name":"Tanaka Tomotika"},{"name":"Andoh Tadao"},{"name":"Shinohara Ayumi"},{"name":"Nakata Mami"}],"ja":[{"name":"増田 俊哉"},{"name":"Yonemori Shigetomo"},{"name":"小山 保夫"},{"name":"武田 美雄"},{"name":"Tanaka Tomotika"},{"name":"Andoh Tadao"},{"name":"Shinohara Ayumi"},{"name":"Nakata Mami"}]},"publication_date":"1999-04","publication_name":{"en":"Journal of Agricultural and Food Chemistry","ja":"Journal of Agricultural and Food Chemistry"},"volume":"Vol.47","number":"No.4","starting_page":"1749","ending_page":"1754","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/jf980864s"],"issn":["0021-8561"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
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{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62974","label":"url"}],"paper_title":{"en":"Hydroquinone glycosides from leaves of Myrisine sequinii","ja":"Hydroquinone glycosides from leaves of Myrisine sequinii"},"authors":{"en":[{"name":"Zhong Xi-Ning"},{"name":"Otsuka Hideaki"},{"name":"Ide Toshinori"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Zhong Xi-Ning"},{"name":"Otsuka Hideaki"},{"name":"Ide Toshinori"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"武田 美雄"}]},"description":{"en":"沖縄産Myrisine sguinii葉部よりarbutin関連の新配糖体6種を単離しその化学構造を明らかにした.","ja":"沖縄産Myrisine sguinii葉部よりarbutin関連の新配糖体6種を単離しその化学構造を明らかにした."},"publication_date":"1998-12-05","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.49","number":"No.7","starting_page":"2149","ending_page":"2153","languages":["eng"],"referee":true,"identifiers":{"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=62996","label":"url"}],"paper_title":{"en":"(+)-Isolarisiresinol 3a-O-sulfate from the leaves of Myrsine sequinii","ja":"(+)-Isolarisiresinol 3a-O-sulfate from the leaves of Myrsine sequinii"},"authors":{"en":[{"name":"Zhong Xi-Ning"},{"name":"Ide Toshinori"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Zhong Xi-Ning"},{"name":"Ide Toshinori"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"武田 美雄"}]},"description":{"en":"沖縄産Myrsine seguinii葉部よりリグナン関連物質としてisolriciresinol-3a-O-sulphateを単離し,その化学構造を明らかにした.","ja":"沖縄産Myrsine seguinii葉部よりリグナン関連物質としてisolriciresinol-3a-O-sulphateを単離し,その化学構造を明らかにした."},"publication_date":"1998-11-20","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.49","number":"No.6","starting_page":"1777","ending_page":"1778","languages":["eng"],"referee":true,"identifiers":{"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=63037","label":"url"}],"paper_title":{"en":"Iridoid glucosides with different acyl moieties from globurarinin and globularimin","ja":"Iridoid glucosides with different acyl moieties from globurarinin and globularimin"},"authors":{"en":[{"name":"Sudo Hirokazu"},{"name":"Ide Toshinori"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Sudo Hirokazu"},{"name":"Ide Toshinori"},{"name":"Otsuka Hideaki"},{"name":"Hirata Eiji"},{"name":"Takushi Anki"},{"name":"武田 美雄"}]},"description":{"en":"石垣島産Premna subscandens 葉部より5種の新イリドイド配糖体を単離し,その化学構造を明らかにした.","ja":"石垣島産Premna subscandens 葉部より5種の新イリドイド配糖体を単離し,その化学構造を明らかにした."},"publication_date":"1998-10","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.49","number":"No.3","starting_page":"783","ending_page":"786","languages":["eng"],"referee":true,"identifiers":{"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"http://pubs.acs.org/cgi-bin/abstract.cgi/jnprdf/1998/61/i08/abs/np9800194.html","label":"url"},{"@id":"https://www.ncbi.nlm.nih.gov/pubmed/9722479","label":"url"},{"@id":"https://www.scopus.com/record/display.url?eid=2-s2.0-0031697981&origin=inward","label":"url"},{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=63015","label":"url"}],"paper_title":{"en":"Nuclear magnetic resonance and biosynthetic studies of neoantimycin and structure elucidation of isoneoantimycin, a minor metabolite related to neoantimycin","ja":"Nuclear magnetic resonance and biosynthetic studies of neoantimycin and structure elucidation of isoneoantimycin, a minor metabolite related to neoantimycin"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Masuda Toshiya"},{"name":"Matsumoto Takashi"},{"name":"Takechi Yuusuke"},{"name":"Shingu Tetsurou"},{"name":"Floss G Heinz"}],"ja":[{"name":"武田 美雄"},{"name":"増田 俊哉"},{"name":"Matsumoto Takashi"},{"name":"Takechi Yuusuke"},{"name":"Shingu Tetsurou"},{"name":"Floss G Heinz"}]},"description":{"en":"In preparation for biosynthetic studies on the 3,4-dihydroxy-2, 6-dimethyl-5-phenylvaleric acid portion of neoantimycin (1), the 1H and 13C NMR signals of 1 were assigned unambiguously by means of 2D correlation spectroscopy and NOE experiments. The previously undetermined absolute stereochemistry at C-15 and C-16 was deduced as (S) and (S). The structure of isoneoantimycin (2) was also elucidated. The methyl groups of methionine and propionate were incorporated stereospecifically into C-13 and C-12 of 1, respectively, and the configuration of the methyl group of methionine is inverted in the process. The results also suggest the intervention of phenylpyruvate as an actual precursor.","ja":"Streptoverticillium orinociの産生する抗生物質neoantimycinの全H,CNMRシグナルを帰属し,その知見に基づき生合成時の立体化学につき検討を加えた.また,同菌が生産する微量成分,isoneoantimycinの化学構造を明らかにした."},"publication_date":"1998-08","publication_name":{"en":"Journal of Natural Products","ja":"Journal of Natural Products"},"volume":"Vol.61","number":"No.8","starting_page":"978","ending_page":"981","languages":["eng"],"referee":true,"identifiers":{"doi":["10.1021/np9800194"],"issn":["0163-3864"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
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{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75604","label":"url"}],"paper_title":{"en":"Studies on monoterpene glucosides and related natural products.XXXII. Iridoid glucosides of Tarenna kotoensis var. gyokushinka","ja":"Studies on monoterpene glucosides and related natural products.XXXII. Iridoid glucosides of Tarenna kotoensis var. gyokushinka"},"authors":{"en":[{"name":"Takeda Yoshio"},{"name":"Nishimura Hiroshi"},{"name":"Inouye Hiroyuki"}],"ja":[{"name":"武田 美雄"},{"name":"Nishimura Hiroshi"},{"name":"Inouye Hiroyuki"}]},"description":{"en":"アカネ科植物ギョクシンカの配糖体成分を検索し,既知のgeniposidic acidとixosideを同定すると共に.新イリドイド配糖体,tarennnosideを単離し,その化学構造を明らかにした.","ja":"アカネ科植物ギョクシンカの配糖体成分を検索し,既知のgeniposidic acidとixosideを同定すると共に.新イリドイド配糖体,tarennnosideを単離し,その化学構造を明らかにした."},"publication_date":"1976","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.24","number":"No.6","starting_page":"1216","ending_page":"1218","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
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{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75608","label":"url"}],"paper_title":{"en":"Studies on monoterpene glucosides and related natural products.XXIII. Biosynthesis of secoiridoid glucosides, gentiopicroside, morroniside, oleuropein and jasminin","ja":"Studies on monoterpene glucosides and related natural products.XXIII. Biosynthesis of secoiridoid glucosides, gentiopicroside, morroniside, oleuropein and jasminin"},"authors":{"en":[{"name":"Inouye Hiroyuki"},{"name":"Ueda Shinichi"},{"name":"Inoue Kenichiro"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Inouye Hiroyuki"},{"name":"Ueda Shinichi"},{"name":"Inoue Kenichiro"},{"name":"武田 美雄"}]},"description":{"en":"種々の標識化合物の植物への投与実験の結果,genntiopicroside型およびoleuropein型,両タイプのセコイリドイド配糖体とも中間にsecologaninを経由して生合成されることを明らかにした.","ja":"種々の標識化合物の植物への投与実験の結果,genntiopicroside型およびoleuropein型,両タイプのセコイリドイド配糖体とも中間にsecologaninを経由して生合成されることを明らかにした."},"publication_date":"1974","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.22","number":"No.3","starting_page":"676","ending_page":"686","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75607","label":"url"}],"paper_title":{"en":"Two iridoid glucosides from Gardenia jasminoides fruits","ja":"Two iridoid glucosides from Gardenia jasminoides fruits"},"authors":{"en":[{"name":"Inouye Hiroyuki"},{"name":"Takeda Yoshio"},{"name":"Nishimura Hiroshi"}],"ja":[{"name":"Inouye Hiroyuki"},{"name":"武田 美雄"},{"name":"Nishimura Hiroshi"}]},"description":{"en":"アカネ科植物クチナシの果実の微量配糖体を検索し,2種の新イリドイド配糖体gardosideおよびscandoside methyl esterを単離し,その化学構造を明らかにした.また,geniposideからgardosideへの化学変換に成功した.","ja":"アカネ科植物クチナシの果実の微量配糖体を検索し,2種の新イリドイド配糖体gardosideおよびscandoside methyl esterを単離し,その化学構造を明らかにした.また,geniposideからgardosideへの化学変換に成功した."},"publication_date":"1974","publication_name":{"en":"Phytochemistry","ja":"Phytochemistry"},"volume":"Vol.13","number":"No.10","starting_page":"2219","ending_page":"2224","languages":["eng"],"referee":true,"identifiers":{"issn":["0031-9422"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75609","label":"url"}],"paper_title":{"en":"On the lignan glucosides of Symplcos lucida","ja":"クロキSymplocos lucidaのlignan配糖体について"},"authors":{"en":[{"name":"Inouye Hiroyuki"},{"name":"Takeda Yoshio"},{"name":"Nishimura Hiroshi"}],"ja":[{"name":"Inouye Hiroyuki"},{"name":"武田 美雄"},{"name":"Nishimura Hiroshi"}]},"description":{"en":"クロキSymplocos lucida葉部から新リグナン配糖体2種を単離し,その化学構造を明らかにした.","ja":"クロキSymplocos lucida葉部から新リグナン配糖体2種を単離し,その化学構造を明らかにした."},"publication_date":"1973","publication_name":{"en":"Journal of the Pharmaceutical Society of Japan","ja":"薬学雑誌"},"volume":"Vol.93","number":"No.1","starting_page":"44","ending_page":"46","languages":["jpn"],"referee":true,"identifiers":{"issn":["0031-6903"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75611","label":"url"}],"paper_title":{"en":"Studies on monoterpene glucosides and related natural products.XVII. The intermediacy of 7-deoxyloganic acid and loganin in the biosynthesis of several iridoid glucosides","ja":"Studies on monoterpene glucosides and related natural products.XVII. The intermediacy of 7-deoxyloganic acid and loganin in the biosynthesis of several iridoid glucosides"},"authors":{"en":[{"name":"Inouye Hiroyuki"},{"name":"Ueda Shinichi"},{"name":"Aoki Yasuhiko"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Inouye Hiroyuki"},{"name":"Ueda Shinichi"},{"name":"Aoki Yasuhiko"},{"name":"武田 美雄"}]},"description":{"en":"標識化合物の種々の植物への投与実験の結果,7-deoxyloganic acidが種々のイリドイド配糖体の生合成中間体であることを明らかにした.また,loganinがその次の中間体として介在していることも明らかにした.","ja":"標識化合物の種々の植物への投与実験の結果,7-deoxyloganic acidが種々のイリドイド配糖体の生合成中間体であることを明らかにした.また,loganinがその次の中間体として介在していることも明らかにした."},"publication_date":"1972","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.20","number":"No.6","starting_page":"1287","ending_page":"1296","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75610","label":"url"}],"paper_title":{"en":"Studies on monoterpene glucosides and related natural products. XVIII. Formation sequences of iridoid glucosides in highly oxidized levels","ja":"Studies on monoterpene glucosides and related natural products. XVIII. Formation sequences of iridoid glucosides in highly oxidized levels"},"authors":{"en":[{"name":"Inouye Hiroyuki"},{"name":"Ueda Shinichi"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Inouye Hiroyuki"},{"name":"Ueda Shinichi"},{"name":"武田 美雄"}]},"description":{"en":"数種の高度に酸化されたイリドイド配糖体が生合成されるとき7-deoxyloganic acid,loganinからの生成過程を種々の標識イリドイド配糖体の植物への投与実験の結果より明らかにした.","ja":"数種の高度に酸化されたイリドイド配糖体が生合成されるとき7-deoxyloganic acid,loganinからの生成過程を種々の標識イリドイド配糖体の植物への投与実験の結果より明らかにした."},"publication_date":"1972","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.20","number":"No.6","starting_page":"1305","ending_page":"1311","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}
{"insert":{"type":"published_papers"},"similar_merge":{"see_also":[{"@id":"https://web.db.tokushima-u.ac.jp/cgi-bin/edb_browse?EID=75612","label":"url"}],"paper_title":{"en":"Studies on monoterpene glucosides and related natural products.XIII. Incorporation of [10-14C]-sweroside into gentiopicroside and the alkaloids in Vinca and Cinchona plants","ja":"Studies on monoterpene glucosides and related natural products.XIII. Incorporation of [10-14C]-sweroside into gentiopicroside and the alkaloids in Vinca and Cinchona plants"},"authors":{"en":[{"name":"Inouye Hiroyuki"},{"name":"Ueda shinichi"},{"name":"Takeda Yoshio"}],"ja":[{"name":"Inouye Hiroyuki"},{"name":"Ueda shinichi"},{"name":"武田 美雄"}]},"description":{"en":"Swerosideの10位を特異的に14Cで標識した化合物を合成氏,その植物への投与実験の結果から,インドールアルカロイドの非トリプトファン部にセコイリドイド配糖体が取り込まれることを証明した.","ja":"Swerosideの10位を特異的に14Cで標識した化合物を合成氏,その植物への投与実験の結果から,インドールアルカロイドの非トリプトファン部にセコイリドイド配糖体が取り込まれることを証明した."},"publication_date":"1971","publication_name":{"en":"Chemical & Pharmaceutical Bulletin","ja":"Chemical & Pharmaceutical Bulletin"},"volume":"Vol.19","number":"No.3","starting_page":"587","ending_page":"594","languages":["eng"],"referee":true,"identifiers":{"issn":["0009-2363"]},"published_paper_type":"scientific_journal"},"priority":"input_data"}