Tokushima University / Educator and Researcher Directory --- Kanemaru, Kaori

Personal Web Page

https://researchmap.jp/read0054357 (researchmap)

Field of Study

○	Food Processing and Preservation Science
○	Functional Food Science
○	Cookery Science

Subject of Study

○	食品成分による抗微生物作用と食品保蔵への応用 (食中毒菌, 腐敗菌, 抗菌活性, 抗酸化活性, 食品加工)
○	食品成分や環境物質による細胞への影響 (細胞保護作用, 細胞毒性, 抗ガン活性, 有用菌増殖活性, 免疫賦活活性, 食品資源の循環利用)
○	調理文化の地域性と郷土食の調査研究 (郷土食, 食文化, 調理)

Book / Paper

Book:

1.	Masaki Hashizume, Koichi Ute, Yumiko Izaki, Masaki Oono, Susumu Nakano, Akira Mizobuchi, Junji Tamatani, Naoyuki Shimomura, Takao Ueda, Katsutoshi Ueno, Fumiaki Nagao, Chikanori Hashimoto, Yasunori Muto, Takeshi Watanabe, Takahiro Kido, Tetsuro Katayama, Yoko Yamashita, Atsushi Tabata, Yuka Sasaki, 島木美香, Takeshige Otoi, Kaori Kanemaru, Takefumi Hattori, Tatsuo Hamano, Katsuyuki Miyawaki, Ryo Anma, Ken-ichi Nishiyama and Mutsuki Aoya : 安全マニュアル, Apr. 2021.

Academic Paper (Judged Full Paper):

1.	Chizuru Sasaki, Satoshi Tamura, Miyuki Suzuki, Kanako Etomi, Nobuya Nii, Junji Hayashi and Kaori Kanemaru : Continuous microwave-assisted step-by-step extraction of bioactive water-soluble materials and fucoidan from brown seaweed Undaria pinnatifida waste, Biomass Conversion and Biorefinery, Vol.14, 7673-7682, 2024. (Link to Publication Site) ● Publication site (DOI): 10.1007/s13399-022-03035-6 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1007/s13399-022-03035-6 (DOI: 10.1007/s13399-022-03035-6)
2.	Rumana Yesmin Hasi, Toshiki Ishikawa, Keigo Sunagawa, Yoshimichi Takai, Hanif Ali, Junji Hayashi, Ryushi Kawakami, Keizo Yuasa, Mutsumi Aihara, Kaori Kanemaru, Hiroyuki Imai and Tamotsu Tanaka : Nonspecific phospholipase C3 of radish has phospholipase D activity toward glycosylinositol phosphoceramide, FEBS Letters, Vol.596, No.23, 3024-3036, 2022. (Summary) Glycosylinositol phosphoceramide (GIPC) is a major sphingolipid in the plasma membranes of plants. Previously, we found an enzyme activity that produces phytoceramide 1-phosphate (PC1P) by hydrolysis of the D position of GIPC in cabbage and named this activity as GIPC-phospholipase D (PLD). Here, we purified GIPC-PLD by sequential chromatography from radish roots. Peptide mass fingerprinting analysis revealed that the potential candidate for GIPC-PLD protein was nonspecific phospholipase C3 (NPC3), which has not been characterized as a PLD. The recombinant NPC3 protein obtained by heterologous expression system in Escherichia coli produced PC1P from GIPC and showed essentially the same enzymatic properties as those we characterized as GIPC-PLD in cabbage, radish and Arabidopsis thaliana. From these results, we conclude that NPC3 is one of the enzymes that degrade GIPC. (Keyword) Phospholipase D / Raphanus / Phospholipases / Sphingolipids / Brassica / Arabidopsis (Tokushima University Institutional Repository) ● Metadata: 117824 (Link to Publication Site) ● Publication site (DOI): 10.1002/1873-3468.14520 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36266963 ● Search Scopus @ Elsevier (PMID): 36266963 ● Search Scopus @ Elsevier (DOI): 10.1002/1873-3468.14520 (Tokushima University Institutional Repository: 117824, DOI: 10.1002/1873-3468.14520, PubMed: 36266963)
3.	Ali Hanif, Morito Katsuya, Rumana Hasi Yesmin, Mutsumi Aihara, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, Koichiro Tsuchiya, Sango Kazunori and Tamotsu Tanaka : Characterization of uptake and metabolism of very long-chain fatty acids in peroxisome-deficient CHO cells, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol.1867, No.2, 159088, 2022. (Summary) Fatty acids (FAs) longer than C20 are classified as very long-chain fatty acids (VLCFAs). Although biosynthesis and degradation of VLCFAs are important for the development and integrity of the myelin sheath, knowledge on the incorporation of extracellular VLCFAs into the cells is limited due to the experimental difficulty of solubilizing them. In this study, we found that a small amount of isopropanol solubilized VLCFAs in aqueous medium by facilitating the formation of the VLCFA/albumin complex. Using this solubilizing technique, we examined the role of the peroxisome in the uptake and metabolism of VLCFAs in Chinese hamster ovary (CHO) cells. When wild-type CHO cells were incubated with saturated VLCFAs (S-VLCFAs), such as C23:0 FA, C24:0 FA, and C26:0 FA, extensive uptake was observed. Most of the incorporated S-VLCFAs were oxidatively degraded without acylation into cellular lipids. In contrast, in peroxisome-deficient CHO cells uptake of S-VLCFAs was marginal and oxidative metabolism was not observed. Extensive uptake and acylation of monounsaturated (MU)-VLCFAs, such as C24:1 FA and C22:1 FA, were observed in both types of CHO cells. However, oxidative metabolism was evident only in wild-type cells. Similar manners of uptake and metabolism of S-VLCFAs and MU-VLCFAs were observed in IFRS1, a Schwan cell-derived cell line. These results indicate that peroxisome-deficient cells limit intracellular S-VLCFAs at a low level by halting uptake, and as a result, peroxisome-deficient cells almost completely lose the clearance ability of S-VLCFAs accumulated outside of the cells. (Tokushima University Institutional Repository) ● Metadata: 116579 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.bbalip.2021.159088 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34848380 ● Search Scopus @ Elsevier (PMID): 34848380 ● Search Scopus @ Elsevier (DOI): 10.1016/j.bbalip.2021.159088 (Tokushima University Institutional Repository: 116579, DOI: 10.1016/j.bbalip.2021.159088, PubMed: 34848380)
4.	Rumana Yesmin Hasi, Dai Majima, Katsuya Morito, Hanif Ali, Kentaro Kogure, Meera Nanjundan, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru and Tamotsu Tanaka : Isolation of glycosylinositol phosphoceramide and phytoceramide 1-phosphate in plants and their chemical stabilities., Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, Vol.1152, 122213, 2020. (Summary) Glycosylinositol phosphoceramide (GIPC) is a sphingophospholipid in plants. Recently, we identified that GIPC is hydrolyzed to phytoceramide 1-phosphate (PC1P) by an uncharacterized phospholipase D activity following homogenization of certain plant tissues. We now developed methods for isolation of GIPC and PC1P from plant tissues and characterized their chemical stabilities. Hydrophilic solvents, namely a lower layer of a mixed solvent system consisting of isopropanol/hexane/water (55:20:25, v/v/v) was efficient solvent for extraction and eluent in column chromatography. GIPC was isolated by Sephadex column chromatography followed by TLC. A conventional method, such as the Bligh and Dyer method, was applicable for PC1P extraction. Specifically, PC1P was isolated by TLC following mild alkali treatment of lipid extracts of plants. The yields of GIPC and PC1P in our methods were both around 50-70%. We found that PC1P is tolerant against heat (up to 125 °C), strong acid (up to 10 M HCl), and mild alkali (0.1 M KOH). In contrast, significant degradation of GIPC occurred at 100 °C and 1.0 M HCl treatment, suggesting the instability of the inositol glycan moiety in these conditions. These data will be useful for further biochemical and nutritional studies on these sphingolipids. (Tokushima University Institutional Repository) ● Metadata: 115195 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.jchromb.2020.122213 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32615533 ● Search Scopus @ Elsevier (PMID): 32615533 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jchromb.2020.122213 (Tokushima University Institutional Repository: 115195, DOI: 10.1016/j.jchromb.2020.122213, PubMed: 32615533)
5.	Hitomi Sakai, Tohru Sakai, Badr Ali Hoida, Kaori Kanemaru and Kumio Yokoigawa : Analysis of cereal extracts as conditioning solutes to suppress the initial attachment of Escherichia coli to abiotic surfaces, European Food Research and Technology, 2020. (Keyword) Cereals / Escherichia coli / Attachment / Abiotic materials (Tokushima University Institutional Repository) ● Metadata: 114680 (Link to Publication Site) ● Publication site (DOI): 10.1007/s00217-020-03444-9 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85081030075 (Tokushima University Institutional Repository: 114680, DOI: 10.1007/s00217-020-03444-9, Elsevier: Scopus)
6.	Hoida Ali Badr, Kaori Kanemaru, Yasuo Oyama and Kumio Yokoigawa : Suppressive effect of edible seaweeds on SOS response of Salmonella typhimurium induced by chemical mutagens, Journal of Environmental Studies, Vol.23, 30-40, 2020. (Link to Publication Site) ● Publication site (DOI): 10.21608/JESJ.2020.205278 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.21608/JESJ.2020.205278 (DOI: 10.21608/JESJ.2020.205278)
7.	Rumana Yesmin Hasi, Makoto Miyagi, Takashi Kida, Tatsuya Fukuta, Kentaro Kogure, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru and Tamotsu Tanaka : Quantitative Analysis of Glycosylinositol Phosphoceramide and Phytoceramide 1-Phosphate in Vegetables, Journal of Nutritional Science and Vitaminology, Vol.65, No.Supplement, S175-S179, 2019. (Summary) Previously, we found an unidentified sphingolipid in cabbage, and determined it as phytoceramide 1-phosphate (PC1P). PC1P is found to be produced from glycosylinositol phosphoceramide (GIPC) by the action of phospholipase D (PLD) activity. Although GIPC is abundant sphingolipid, especially in cruciferous vegetables, amount of daily intake, digestibility and nutritional activity of GIPC are not well understood. Here, we investigated amounts of GIPC and PC1P in vegetables. GIPC was found in all vegetables examined (13 kinds) at levels 3-20 mg/100 g (wet weight). On the other hand, PC1P was present in limited vegetables which show higher GIPC-PLD activity, such as inner cabbage leaves (5.2 mg/100 g). Because PC1P is formed during homogenization by activated GIPC-PLD, level of PC1P in boiled cabbage leaves was very low. Although digestibility of GIPC is unknown at present, a portion of dietary GIPC is considered to be converted to PC1P during mastication by plant-derived GIPC-PLD activity in some vegetables. (Keyword) Brassica / Ceramides / Glycosphingolipids / Inositol / Phosphates / Phospholipase D / Plant Leaves / Sphingolipids / Vegetables (Tokushima University Institutional Repository) ● Metadata: 115197 (Link to Publication Site) ● Publication site (DOI): 10.3177/jnsv.65.S175 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31619623 ● Summary page in Scopus @ Elsevier: 2-s2.0-85073476996 (Tokushima University Institutional Repository: 115197, DOI: 10.3177/jnsv.65.S175, PubMed: 31619623, Elsevier: Scopus)
8.	Hasi Yesmin Rumana, Makoto Miyagi, Katsuya Morito, Toshiki Ishikawa, Maki Kawai-Yamada, Hiroyuki Imai, Tatsuya Fukuta, Kentaro Kogure, Kaori Kanemaru, Junji Hayashi, Ryushi Kawakami and Tamotsu Tanaka : Glycosylinositol phosphoceramide-specific phospholipase D activity catalyzes transphosphatidylation, The Journal of Biochemistry, Vol.166, No.5, 441-448, 2019. (Summary) Glycosylinositol phosphoceramide (GIPC) is the most abundant sphingolipid in plants and fungi. Recently, we detected GIPC-specific phospholipase D (GIPC-PLD) activity in plants. Here, we found that GIPC-PLD activity in young cabbage leaves catalyzes transphosphatidylation. The available alcohol for this reaction is a primary alcohol with a chain length below C4. Neither secondary alcohol, tertiary alcohol, choline, serine nor glycerol serves as an acceptor for transphosphatidylation of GIPC-PLD. We also found that cabbage GIPC-PLD prefers GIPC containing two sugars. Neither inositol phosphoceramide, mannosylinositol phosphoceramide nor GIPC with three sugar chains served as substrate. GIPC-PLD will become a useful catalyst for modification of polar head group of sphingophospholipid. (Keyword) Biocatalysis / Brassica / Ceramides / Inositol / Molecular Structure / Phosphatidylcholines / Phospholipase D / Plant Leaves (Tokushima University Institutional Repository) ● Metadata: 113685 (Link to Publication Site) ● Publication site (DOI): 10.1093/jb/mvz056 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31504617 ● Summary page in Scopus @ Elsevier: 2-s2.0-85073764089 (Tokushima University Institutional Repository: 113685, DOI: 10.1093/jb/mvz056, PubMed: 31504617, Elsevier: Scopus)
9.	Yurie Funakoshi, Ayako Azuma, Mizuki Ishikawa, Satoru Itsuki, Yasuaki Tamura, Kaori Kanemaru, Shogo Hirai and Yasuo Oyama : Cytometrical analysis of the adverse effects of indican, indoxyl, indigo, and indirubin on rat thymic lymphocytes, Toxicology Research, Vol.7, 513-520, 2018. (Summary) Many businesses thrive by producing health supplements from agricultural products, as exemplified by the production of functional (or health) food using plants traditionally cultivated in the rural areas. Dyes, such as indican, indigo, indoxyl, and indirubin, present in dye plants, possess antibacterial, antifungal, and antiproliferative activities. However, these effects may also lead to cytotoxicity. Thus, studies in normal mammalian cells are necessary to identify cytotoxicity and prevent adverse effects of functional foods that contain these dyes. In this study, the effects of indican, indigo, indoxyl, and indirubin were evaluated by flow cytometry using appropriate fluorescent probes in rat thymic lymphocytes. Among the dyes analyzed, indirubin exerted distinct cellular activities. Treatment with indirubin (10 30 µM) increased the population of shrunken dead cells. The side scatter, but not forward scatter, increased in indirubin-treated living cells. It increased the population of annexin V-bound living and dead cells and that of dead cells without annexin V. Indirubin elevated intracellular Ca2+, but not Zn2+ levels. The cellular content of superoxide anions and increased glutathione decreased. Indirubin depolarized the cellular plasma and mitochondrial membranes. It did not potentiate or attenuate the cytotoxicity of A23187 (Ca2+ overload) and H2O2 (oxidative stress). The results suggested that indirubin induces both apoptotic and non-apoptotic cell death. It may be difficult to predict and prevent adverse effects of indirubin due to its diverse activities on normal mammalian cells. Therefore, indirubin should be removed from products that contain dye plant extracts. (Keyword) Indigo / Indirubin / Indoxyl / Indican (Tokushima University Institutional Repository) ● Metadata: 111988 (Link to Publication Site) ● Publication site (DOI): 10.1039/C7TX00244K (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85046849441 (Tokushima University Institutional Repository: 111988, DOI: 10.1039/C7TX00244K, Elsevier: Scopus)
10.	Honoka Wada, Keisuke Oyama, Risa Kamae, Toshiya Masuda, Kaori Kanemaru, Kumio Yokoigawa and Yasuo Oyama : Zinc-dependent and independent actions of hydroxyhydroquinone on rat thymic lymphocytes, Drug and Chemical Toxicology, Vol.9, 1-6, 2018. (Summary) Coffee contains hydroxyhydroquinone (HHQ). HHQ is one of by-products released during bean roasting. Therefore, it is important to elucidate the bioactivity of HHQ to predict its beneficial or adverse effects on humans. We studied zinc-dependent and independent actions of commercially-procured synthetic HHQ in rat thymocytes using flow cytometric techniques with propidium iodide, FluoZin-3-AM, 5-chloromethylfluorescein diacetate, and annexin V-FITC. HHQ at 10¬50 µM elevated intracellular Zn2+ levels by releasing intracellular Zn2+. HHQ at 10 µM increased cellular thiol content in a Zinc-dependent manner. However, HHQ at 30 50 µM reduced cellular thiol content. Although the latter actions of HHQ (30 50 µM) were suggested to increase cell vulnerability to oxidative stress, HHQ at 0.3 100 µM significantly protected cells against oxidative stress induced by H2O2. The process of cell death induced by H2O2 was delayed by HHQ, although both H2O2 and HHQ increased the population of annexin V-positive living cells. However, HHQ at 10 30 µM promoted cell death induced by A23187, a calcium ionophore. HHQ at 10 30 µM exerted contrasting effects on cell death caused by oxidative stress and Ca2+ overload. Because HHQ is considered to possess diverse cellular actions, coffee with reduced amount of HHQ may be preferable to avoid potential adverse effects. (Keyword) Zinc / Hydroyxhydroquinone (Tokushima University Institutional Repository) ● Metadata: 111979 (Link to Publication Site) ● Publication site (DOI): 10.1080/01480545.2018.1429462 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1080/01480545.2018.1429462 (Tokushima University Institutional Repository: 111979, DOI: 10.1080/01480545.2018.1429462)
11.	Kaori Kanemaru, Goto Tsukie, Badr Ali Hoida and Kumio Yokoigawa : Determination of binding affinity of poly-gamma-glutamate to Shiga toxin, Journal of Food Biochemistry, Vol.42, No.5, e12538, 2018. (Keyword) Escherichia coli O157:H7 / Poly-gamma-glutamate / Shiga toxin (Tokushima University Institutional Repository) ● Metadata: 113899 (Link to Publication Site) ● Publication site (DOI): 10.1111/jfbc.12538 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1111/jfbc.12538 (Tokushima University Institutional Repository: 113899, DOI: 10.1111/jfbc.12538)
12.	Yumiko Nishimura-Danjobara, Keisuke Oyama, Kaori Kanemaru, Keiko Takahashi, Kumio Yokoigawa and Yasuo Oyama : N-(3-oxododecanoyl)-L-homoserine-lactone, a quorum sensing molecule, affects cellular content of nonprotein thiol content in rat lymphocytes: Its relation with intracellular Zn2+, Chemico-Biological Interactions, Vol.280, 28-32, 2018. (Summary) Cellular actions of N-(3-oxododecanoyl)-L-homoserine-lactone (ODHL), a quorum sensing molecule of bacteria, were studied on rat thymocytes using a flow cytometer with appropriate fluorescent dyes to elucidate the effects of ODHL on host cells. A bell-shaped concentration-response relation was observed in the ODHL-induced changes in cellular glutathione content ([GSH]i). ODHL concentration-dependently increased intracellular Zn2+ levels ([Zn2+]i) and cellular O2- content ([O2-]i). The bell-shaped relation induced by ODHL can be explained as follows: a low concentration of ODHL is expected to induce moderate oxidative stress that intracellularly releases Zn2+ by converting thiols to disulfides. A slight elevation of [Zn2+]i may increase the [GSH]i. On the other hand, it is likely that a high concentration of ODHL causes severe oxidative stress that further causes both the decrease in [GSH]i and the increase in [Zn2+]i. Excessive increase in [Zn2+]i may augment oxidative stress that further decreases the [GSH]i. Other notable actions induced by ODHL included the elevation of [Zn2+]i by Zn2+ influx and the increase in [GSH]i under Zn2+-free conditions. Therefore, it is suggested that ODHL elicits diverse actions on host cells. (Keyword) 4-Butyrolactone / Animals / Apoptosis / Cells, Cultured / Glutathione / Homoserine / Lymphocytes / Male / Oxidative Stress / Quorum Sensing / Rats / Rats, Wistar / Sulfhydryl Compounds / Thymus Gland / Zinc (Tokushima University Institutional Repository) ● Metadata: 111976 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.cbi.2017.12.013 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29223568 ● Search Scopus @ Elsevier (PMID): 29223568 ● Search Scopus @ Elsevier (DOI): 10.1016/j.cbi.2017.12.013 (Tokushima University Institutional Repository: 111976, DOI: 10.1016/j.cbi.2017.12.013, PubMed: 29223568)
13.	Norio Kamemura, Keisuke Oyama, Kaori Kanemaru, Kumio Yokoigawa and Yasuo Oyama : Diverse cellular actions of tert-butylhydroquinone, a food additive, on rat thymocytes, Toxicology Research, Vol.6, 922-929, 2017. (Summary) Tertiary butylhydroquinone (TBHQ) is a food additive that possesses antioxidant activity. Its alternative applications have been explored in recent studies. However, there is controversy regarding safety. In this study using rat thymocytes, the cellular actions of TBHQ at sublethal concentrations were examined. TBHQ at concentrations of 3 µM or more elevated intracellular Zn2+ concentration ([Zn2+]i) in a dose-dependent manner, by increasing membrane Zn2+ permeability and releasing Zn2+ from cellular stores. TBHQ at 30 µM significantly increased side scatter (cell density) and the exposure of phosphatidylserine (PS) on cell membrane surfaces. It also decreased cellular glutathione (GSH) content without affecting cell lethality. Forward scatter was attenuated by 100 µM TBHQ. Thus, it is considered that TBHQ at sublethal concentrations (30 µM or less) exerts some adverse actions on cells. TBHQ at 10 30 µM attenuated the increase in cell lethality induced by hydrogen peroxide (H2O2), while potentiation of H2O2 cytotoxicity by 100 µM TBHQ was observed. The range of concentrations of TBHQ from benefit to toxicity under in vitro conditions may be 10 30 µM. Although TBHQ exhibits antioxidative actions at concentrations that are lower than those which elicit adverse cellular effects, sublethal levels of TBHQ cause some adverse actions that may be clinically concerned. (Keyword) food additive (Tokushima University Institutional Repository) ● Metadata: 111981 (Link to Publication Site) ● Publication site (DOI): 10.1039/C7TX00183E (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1039/C7TX00183E (Tokushima University Institutional Repository: 111981, DOI: 10.1039/C7TX00183E)
14.	Badr Ali Hoida, Takahashi Keiko, Ryushi Kawakami, Yasuo Oyama, Kumio Yokoigawa and Kaori Kanemaru : Screening and analysis of edible seaweeds in the ability to adsorb Shiga toxin., European Food Research and Technology, Vol.243, No.12, 2147-2153, 2017. (Keyword) Shiga toxin / Seaweed / Ulva linza Linnaeus / Rhamnan sulfate (Tokushima University Institutional Repository) ● Metadata: 111019 (Link to Publication Site) ● Publication site (DOI): 10.1007/s00217-017-2915-1 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1007/s00217-017-2915-1 (Tokushima University Institutional Repository: 111019, DOI: 10.1007/s00217-017-2915-1)
15.	Maki Takeda, Keisuke Oyama, Norio Kamemura, Kaori Kanemaru, Keizo Yuasa, Kumio Yokoigawa and Yasuo Oyama : Change in plasma membrane potential of rat thymocytes by tert-butylhydroquinone, a food additive: Possible risk on lymphocytes, Food and Chemical Toxicology, Vol.109, No.1, 296-301, 2017. (Summary) Tertiary butylhydroquinone (TBHQ) is a food additive and has various beneficial actions under in vitro and in vivo experimental conditions. Therefore, it is necessary to collect additional data on the toxicity of TBHQ in order to avoid adverse effects during clinical applications. Changes in plasma membrane potential are associated with changes in physiological functions even in non-excitable cells such as lymphocytes. Thus, compounds that affect membrane potential may modify some lymphocytic functions. The effect of TBHQ on plasma membrane potential was examined in rat thymocytes using flow cytometric techniques. Treatment of rat thymocytes with TBHQ caused hyperpolarization and then depolarization. The TBHQ-induced hyperpolarization was due to the activation of Ca2+-dependent K+ channels. TBHQ elevated intracellular Ca2+ levels. The depolarization by TBHQ was caused by a nonspecific increase in membrane ionic permeability. Both the sustained depolarization and elevation of intracellular Ca2+ level by TBHQ are thought to be adverse for thymocytes because such changes disturb membrane and intracellular signaling. The thymus is most active during neonatal and pre-adolescent periods. If TBHQ exerts adverse actions on thymocytes, it may result in an immunotoxic effect in neonates and adolescents. (Keyword) tert-butylhydroquinone / food additive / membrane potential / lymphocytes / calcium (Tokushima University Institutional Repository) ● Metadata: 111984 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.fct.2017.09.017 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28899772 ● Summary page in Scopus @ Elsevier: 2-s2.0-85029351916 (Tokushima University Institutional Repository: 111984, DOI: 10.1016/j.fct.2017.09.017, PubMed: 28899772, Elsevier: Scopus)
16.	Goto Tsukie, Makiko Tsuji, Kaori Kanemaru and Kumio Yokoigawa : Adsorption of Shiga Toxin to Poly-γ Glutamate Precipitated., Journal of Food Science, Vol.81, No.12, 2977-2981, 2016. (Tokushima University Institutional Repository) ● Metadata: 111020 (Link to Publication Site) ● Publication site (DOI): 10.1111/1750-3841.13540 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1111/1750-3841.13540 (Tokushima University Institutional Repository: 111020, DOI: 10.1111/1750-3841.13540)
17.	Eiko Niwa, Tsuyoshi Mitani, Shohei Saitoh, Kaori Kanemaru, Shiro Ishida, Kumio Yokoigawa and Yasuo Oyama : Zinc increases vulnerability of rat thymic lymphocytes to arachidonic acid under in vitro conditions, Food and Chemical Toxicology, Vol.96, 177-182, 2016. (Summary) Previous studies on the cytotoxicity of arachidonic acid (ARA) elucidated the involvement of oxidative stress and Ca2+. In the present study, the Zn2+-related cytotoxicity of ARA was studied by a flow cytometric technique with appropriate fluorescent probes in rat thymocytes. Addition of 10 µM ZnCl2 enhanced the increase in cell lethality induced by 10 µM ARA. The removal of Zn2+ by Zn2+ chelators attenuated the ARA-induced increase in cell lethality. Thus, Zn2+ is suggested to be involved in ARA cytotoxicity. ARA at 3 10 µM elevated intracellular Zn2+ level. The Zn2+ chelators attenuated the ARA-induced increase in intracellular Zn2+ level while ARA significantly increased intracellular Zn2+ level in the presence of 3 µM ZnCl2, suggesting the involvement of external Zn2+. Zn2+ reportedly exerts cytotoxic action under oxidative stress induced by hydrogen peroxide, via an excessive increase in intracellular Zn2+ levels. Since ARA induces oxidative stress, the simultaneous administration of zinc and ARA may be harmful. (Keyword) Polyunsaturated fatty acids (Tokushima University Institutional Repository) ● Metadata: 110419 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.fct.2016.08.008 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27515868 ● Search Scopus @ Elsevier (PMID): 27515868 ● Search Scopus @ Elsevier (DOI): 10.1016/j.fct.2016.08.008 (Tokushima University Institutional Repository: 110419, DOI: 10.1016/j.fct.2016.08.008, PubMed: 27515868)
18.	Hiromitsu Tsuzuki, Shota Inoue, Daiki Kobayashi, Gantulga Uuganbaatar, Kaori Kanemaru, Kumio Yokoigawa and Yasuo Oyama : Methyl cinnamate increases cell vulnerability to oxidative stress induced by hydrogen peroxide in rat thymocytes, Fundamental Toxicological Sciences, Vol.3, No.3, 121-125, 2016. (Summary) Methyl cinnamate (MC) and essential oils containing MC possess beneficial antimicrobial, antifungal, and insecticidal effects, among others. Such effects are related to the biocidal action of MC. The antioxidant activity of MC has also been reported elsewhere. It has been suggested that MC may be cytotoxic to cells exposed to oxidative stress. To test this possibility, the effect of MC on rat thymocytes was examined while the cells were subjected to oxidative stress induced by hydrogen peroxide (H2O2). Flow cytometric techniques with appropriate fluorescent probes were used for quantification. MC increased cell vulnerability to oxidative stress via acceleration of the cell death process and/or potentiation of oxidative stress. The use of MC is widespread because of its beneficial actions, and thus further attention should be paid to whether MC is effective under oxidative stress. (Tokushima University Institutional Repository) ● Metadata: 110051 (Link to Publication Site) ● Publication site (DOI): 10.2131/fts.3.121 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.2131/fts.3.121 (Tokushima University Institutional Repository: 110051, DOI: 10.2131/fts.3.121)
19.	松下純子, 後藤月江, Kaori Kanemaru, 遠藤千鶴, 長尾久美子, 有内尚子 and 高橋啓子 : Survey of Annual Events and Their Special Foods in Tokushima Prefecture, Journal of Cookery Science of Japan, Vol.47, No.1, 42-48, 2014. (Summary) We carried out survey as to what people in Tokushima prefecture eat at various annual events except on New Year's Day from 2009 to 2010.The subjects of this survey were residents of Tokushima prefecture who have lived there for more than 10 years. The subjects were divided into three age groups; 1) those younger than 30 years old; 2) those between 30 and 50; and 3) those over 50.Our findings showed that eating cakes on Christmas Day and buckwheat noodles at night of the New Year's Eve is fairly common. This tendency is rampant among the people over 30 and fewer among younger generations, though the contrast is not very sharp.People over 50 who used to have a habit of cooking by themselves the above food for special events, tend to buy the ready cooked ones instead of preparing them in their houses. (Keyword) annual events / special foods / Tokushima (Link to Publication Site) ● Publication site (DOI): 10.11402/cookeryscience.47.42 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282680481393536 ● Search Scopus @ Elsevier (DOI): 10.11402/cookeryscience.47.42 (DOI: 10.11402/cookeryscience.47.42, CiNii: 1390282680481393536)
20.	後藤月江, 松下純子, Kaori Kanemaru, 遠藤千鶴, 長尾久美子, 有内尚子 and 高橋啓子 : A Survey of Foods for Rites of Passage in Tokushima Prefecture, Journal of Cookery Science of Japan, Vol.46, No.6, 389-394, 2013. (Keyword) Tokushima / rites of passage / foods for rites of passage (Link to Publication Site) ● Publication site (DOI): 10.11402/cookeryscience.46.389 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282680482791936 ● Search Scopus @ Elsevier (DOI): 10.11402/cookeryscience.46.389 (DOI: 10.11402/cookeryscience.46.389, CiNii: 1390282680482791936)
21.	Yusuke Takahashi, Kaori Kanemaru, Shoji Imai, Norikazu Miyoshi, Takuya Kawanai and Yasuo Oyama : Yttrium decreases the intracellular Zn²⁺ concentration in rat thymocytes by attenuating a temperature-sensitive Zn²⁺ influx, Environmental Toxicology and Pharmacology, Vol.34, No.2, 574-578, 2012. (Summary) Yttrium is used in the production of various electronic devices because the alloy it contains enhances or modifies the properties of other elements. In order to study the cytotoxic action of yttrium, the effect of yttrium chloride (YCl3) on the intracellular Zn2+ level was examined in rat thymocytes using a flow cytometer with FluoZin-3-AM and propidium iodide. The application of YCl3 significantly decreased the intensity of the FluoZin-3 fluorescence, suggesting a decrease in the intracellular Zn2+ level or quenching of the FluoZin-3 fluorescence by Y3+. However, since Y3+ did not attenuate the FluoZin-3 fluorescence under cell-free conditions, the latter suggestion was ruled out. Rat thymocytes possess a temperature-sensitive membrane pathway that carries Zn2+ into the cells. The application of YCl3 attenuated the FluoZin-3 fluorescence augmented by externally applied ZnCl2 in a concentration-dependent manner. This suggested that Y3+ inhibited the Zn2+ influx, resulting in the decrease in the intracellular Zn2+ level. Yttrium may induce dyshomeostasis of intracellular Zn2+, leading to some cytotoxic actions. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.etap.2012.07.002 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22854244 ● Summary page in Scopus @ Elsevier: 2-s2.0-84864332430 (DOI: 10.1016/j.etap.2012.07.002, PubMed: 22854244, Elsevier: Scopus)
22.	Kazuki Koizumi, Kawanai Takuya, Erika Hashimoto, Yasuhiro Kanbara, Toshiya Masuda, Kaori Kanemaru, Yoshiro Okano and Yasuo Oyama : Cytometric analysis on cytotoxicity of curcumin on rat thymocytes: Proapoptotic and antiapoptotic actions of curcumin, Toxicology In Vitro, Vol.25, No.4, 985-990, 2011. (Summary) Curcumin exhibits various pharmacological actions including anti-inflammatory, anti-infectious, and anticancer actions. Furthermore, the supplements containing curcumin are supplied for persons consuming alcoholic beverage. A primary criterion for an ingredient ingested by general population is that it exerts no harmful effect. In this study, we examined the effect of curcumin on rat thymocytes to see if curcumin exerts cytotoxicity on normal cells. The incubation with 10 µM curcumin for 24 h increased the population of dead cells while it was not the case for 5 µM or less. Curcumin at 5-10 µM increased the populations of shrunken cells and the cells positive to annexin V, phenomena for early stage of apoptosis. However, the incubation with 10 µM curcumin suppressed the increase in population of cells with hypodiploid DNA, a phenomenon for late stage of apoptosis. Thus, curcumin at 10 µM may show both proapoptotic and antiapoptotic actions. The simultaneous incubation with 5 µM, but not 3 µM, curcumin and 0.5 % ethanol increased the population of shrunken cells. It is likely that curcumin at 5 µM or more exerts cytotoxic action on normal cells although many studies show some anticancer actions of curcumin at 10 µM or more on cancer cells. (Keyword) Animals / Annexin A5 / Antineoplastic Agents / Apoptosis / Curcumin / Dose-Response Relationship, Drug / Flow Cytometry / Rats / Rats, Wistar / Thymus Gland (Link to Publication Site) ● Publication site (DOI): 10.1016/j.tiv.2011.03.010 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21419841 ● Search Scopus @ Elsevier (PMID): 21419841 ● Search Scopus @ Elsevier (DOI): 10.1016/j.tiv.2011.03.010 (DOI: 10.1016/j.tiv.2011.03.010, PubMed: 21419841)
23.	Yoshimi Shingai, Aya Fujimoto, Asuka Nakajima, Minoru Saito, Kaori Kanemaru, Toshiya Masuda and Yasuo Oyama : Cytotoxic characteristics of two isomeric dimers produced by oxidation of sesamol, an antioxidant in sesame oil, Journal of Health Science, Vol.57, No.5, 425-431, 2011. (Summary) Antioxidants themselves are oxidized to prevent oxidation of other molecules. One may ask if the oxidized antioxidants are safe for humans. However, there is very little information on the toxicity of oxidized antioxidants. We previously identified cytotoxic compounds in the products from oxidation of sesamol, a potent antioxidant in sesame oil. In this study using a flow cytometer with fluorescent probes, we revealed cytotoxic characteristics of two isomeric dimers (dimer A and B) in rat thymocytes. Increase in cell lethality by dimer A was more profound than those by sesamol and dimer B. The incubation of cells with dimer A increased the populations of shrunken cells and the cells with phosphatidylserine exposed on outer surface of cell membranes. Since these phenomena are parameters for early stage of apoptosis, the results indicate that dimer A may promote the process of apoptosis. However, the population of the cells containing hypodiploid DNA, a parameter for late stage of apoptosis, was decreased by the incubation with dimer A. It was not the case for dimer B. Results indicate that dimer A may inhibit the degradation of DNA during apoptosis. Taken together, it is likely that dimer A exerts both proapoptotic action and inhibitory action on late stage of apoptosis in rat thymocytes. (Keyword) antioxidant / apoptosis / cytotoxicity / oxidation / sesamol (Link to Publication Site) ● Publication site (DOI): 10.1248/jhs.57.425 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204498372864 ● Search Scopus @ Elsevier (DOI): 10.1248/jhs.57.425 (DOI: 10.1248/jhs.57.425, CiNii: 1390001204498372864)
24.	Mayumi YAMAMOTO, Jin Nagazumi, Makoto Ohashi, Kaori Kanemaru, Yoshiyasu Terashima and Masami Nagamune : Attempt of Student Volunteers in the Special Needs Education, Journal of University Education Research, Vol.0, No.6, 102-107, 2010. (Summary) 障害を持つ児童生徒への教育は特別支援教育に移行し，学習障害， ADHD，高機能自閉症(広汎性発達障害)などの新しい障害領域が加えられた．制度的にはこのような変化があるが，学校現場の支援体制は物的環境，人的環境において整っていない．大学が県・市の教育委員会と連携し，大学生を学習支援ボランティアとして小中学校に派遣し，教員の補助的役割を担うことは，特別支援教育にとってどのような影響があるかを報告することを目的とした．県・市の教育委員会から各10名程度の大学生の募集があったので， 3・4年生を対象として募集した．募集に応じた学生は事前オリエンテーションを各教育委員会から受け，小中学校に4時間/1日，派遣された．派遣校教員と学生ボランティアへの面接，質問紙調査から「教室に支援の手と目が増えた(学習支援ボランティアがいることで子どもをみてくれる人が増え，支援してくれる人が増えた)」，「子どもの反応から対応を考えるカがついた」などの評価が得られた． (Keyword) Special support education / University students / volunteer / Board education (Tokushima University Institutional Repository) ● Metadata: 82695 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050564287417205632 (Tokushima University Institutional Repository: 82695, CiNii: 1050564287417205632)
25.	Yoko Sakanashi, Midori Morimoto, Yumiko Nishimura, Hiroko Matsui, Kaori Kanemaru, Toshiya Masuda and Yasuo Oyama : Cytometric analysis of the cytotoxic action of adenosine 5'-monophosphate on rat thymocytes, Journal of Health Science, Vol.54, No.6, 692-696, 2008. (Summary) The cascade of adenosine 5'-monophosphate -activated protein kinase (AMPK) is known to be a sensor of cellular energy charge. In this context, a paradigm for obesity treatment via the activation of AMPK has attracted the suppliers of complementary medicines and supplements. It is possible that products that increase the concentration of adenosine 5'-monophosphate (AMP) in the body would be efficacious in reducing body weight. However, since there is currently little information concerning the toxicity of AMP, the cytotoxic action of AMP on rat thymocytes was examined by flow cytometry. Incubation of cells with AMP at a concentration of 30 µM or more for 24 h significantly increased the populations of dead cells, shrunken cells, and cells containing hypodiploidal DNA in a concentration-dependent manner. Z-VAD-FMK, a pan-inhibitor of caspases, attenuated the AMP-induced changes in cell populations. It is concluded that AMP at a concentration of 30 µM or more exerts a cytotoxic action, which is dependent on the activation of caspases. (Keyword) cytotoxicity / adenosine 5'-monophosphate / flow cytometry / thymocyte (Link to Publication Site) ● Publication site (DOI): 10.1248/jhs.54.692 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204497739648 ● Search Scopus @ Elsevier (DOI): 10.1248/jhs.54.692 (DOI: 10.1248/jhs.54.692, CiNii: 1390001204497739648)
26.	川染節江, 板倉一枝, 松島文子, 横山弥枝, 奥野元子, 安藤真美, 神田知子, 五島淑子, 櫻井菜穂子, 花井玲子, 井川佳子, 奥田弘枝, 岡本洋子, 小園佳美, 人見哲子, 和田治子, 藤井わか子, 宇高順子, 亀岡恵子, 峰弘子, 川端和子, 武田珠美, 小西文子 and Kaori Kanemaru : 災害時のメニュー開発 -中国・四国支部報告-, 日本調理科学会誌, Vol.41, No.1, 64-68, 2008.
27.	Kanna Horimoto, Yumiko Nishimura, Tomohiro Oyama, Kyoko Onoda, Hiroko Matsui, Toshihisa Oyama, Kaori Kanemaru, Toshiya Masuda and Yasuo Oyama : Reciprocal effects of glucose on the process of cell death induced by calcium ionophore or H2O2 in rat lymphocytes, Toxicology, Vol.225, No.2-3, 97-108, 2006. (Summary) We have examined the effects of glucose at high concentrations on the process of cell death induced by excessive increase in intracellular Ca2+ concentration ([Ca2+]i) or oxidative stress in rat lymphocytes. The cell death elicited by the excessive increase in [Ca2+]i seemed to be induced by an activation of Ca2+-dependent K+ channels because the inhibitors for Ca2+-dependent K+ channels attenuated the decrease in cell viability. Glucose at 30-50 mM augmented the decrease in cell viability by the excessive increase in [Ca2+]i. It was not specific for glucose because it was the case for sucrose or NaCl, suggesting an involvement of increased osmolarity in adverse action of glucose. On the contrary, glucose protected the cells suffering from oxidative stress induced by H2O2, one of reactive oxygen species. It was also the case for fructose or sucrose, but not for NaCl. The process of cell death induced by H2O2 started, being independent from the presence of glucose. Glucose delayed the process of cell death induced by H2O2. Sucrose and fructose also protected the cells against oxidative stress. The reactivity of sucrose to reactive oxygen species is lower than those of glucose and fructose. The order in the reactivity cannot explain the protective action of glucose. Glucose at high concentrations exerts reciprocal actions on the process of cell death induced by the oxidative stress and excessive increase in [Ca2+]i. (Keyword) Animals / Calcimycin / Calcium / Cell Death / Cell Survival / Charybdotoxin / Clotrimazole / Dose-Response Relationship, Drug / Flow Cytometry / Glucose / Hydrogen Peroxide / Ionophores / Male / Osmolar Concentration / Oxidative Stress / Rats / Rats, Wistar / T-Lymphocytes (Link to Publication Site) ● Publication site (DOI): 10.1016/j.tox.2006.05.004 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16784802 ● Search Scopus @ Elsevier (PMID): 16784802 ● Search Scopus @ Elsevier (DOI): 10.1016/j.tox.2006.05.004 (DOI: 10.1016/j.tox.2006.05.004, PubMed: 16784802)
28.	Yumiko Nishimura, Jun-ya Yamaguchi, Aimi Kanada, Kanna Horimoto, Kaori Kanemaru, Masaya Satoh and Yasuo Oyama : Increase in intracellular Cd²⁺ concentration of rat cerebellar granule neurons incubated with cadmium chloride: Cadmium cytotoxicity under external Ca²⁺-free condition, Toxicology In Vitro, Vol.20, No.2, 211-216, 2006. (Summary) In order to examine the cadmium cytotoxicity unrelated to external Ca(2+), the effects of micromolar CdCl(2) on intracellular Cd(2+) concentration, cellular content of glutathione, and cell viability of rat cerebellar granule neurons were examined under normal Ca(2+) and external Ca(2+)-free conditions, using a laser confocal microscope with fluorescent probes, fluo-3-AM, 5-chloromethylfluorescein (CMF) diacetate, and propidium iodide. CdCl(2) (10-300muM) dose-dependently increased the intensity of fluo-3 fluorescence. Exposure to CdCl(2) equally enhanced the fluo-3 fluorescence under both Ca(2+) conditions and MnCl(2) did not quench the CdCl(2)-enhanced fluorescence. The results indicate that the enhancement of fluo-3 fluorescence is due to the increase in intracellular Cd(2+) concentration. CdCl(2) at 100-300muM decreased the intensity of CMF fluorescence, indicating the decrease in cellular content of glutathione. The population of cells stained with propidium (dead cells) was increased by 100-300muM CdCl(2). Similar results described above were also observed under external Ca(2+)-free condition. It is suggested that some of cytotoxic actions of CdCl(2) on neurons are unrelated to external Ca(2+), one of main sources for increasing intracellular Ca(2+) concentration. (Keyword) cadmium / cytotoxicity (Link to Publication Site) ● Publication site (DOI): 10.1016/j.tiv.2005.06.006 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16061347 ● Summary page in Scopus @ Elsevier: 2-s2.0-30644476948 (DOI: 10.1016/j.tiv.2005.06.006, PubMed: 16061347, Elsevier: Scopus)
29.	Yumiko Nishimura, Aimi Kanada, Jun-ya Yamaguchi, Kanna Horimoto, Masako Kobayashi, Tomoko Tatsuishi, Kaori Kanemaru, Shin-ya Ueno and Yasuo Oyama : Cytometric analysis of lidocaine-induced cytotoxicity: a model experiment using rat thymocytes, Toxicology, Vol.218, No.1, 48-57, 2006. (Summary) Lidocaine is a local anesthetic possessing both lipophilic and hydrophilic properties. It also acts as a surfactant. Thus, the disruption of membranes, resulting in necrosis, is one of possible mechanisms for lidocaine-induced cytotoxicity. However, lidocaine is reported to induce apoptosis. Therefore, in order to compare two mechanisms for cell death induced by lidocaine, the effects of millimolar lidocaine were examined on rat thymocytes by a flow cytometer with appropriate fluorescent probes. Lidocaine decreased the population of living cells with phosphatidylserine-exposed membranes, one of markers for early stage of apoptosis, and increased the population of dead cells without increasing that of cells with hypodiploidal DNA. Lidocaine at millimolar concentrations may deteriorate the membranes of such apoptotic living cells rather than those of intact living cells, resulting in necrosis. It is suggested that the process of apoptosis is not completed in the presence of millimolar lidocaine. (Keyword) lidocaine (Link to Publication Site) ● Publication site (DOI): 10.1016/j.tox.2005.09.016 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 16263203 ● Summary page in Scopus @ Elsevier: 2-s2.0-28744459542 (DOI: 10.1016/j.tox.2005.09.016, PubMed: 16263203, Elsevier: Scopus)
30.	Aimi Kanada, Yumiko Nishimura, Jun-ya Yamaguchi, Masako Kobayashi, Kyoko Mishima, Kanna Horimoto, Kaori Kanemaru and Yasuo Oyama : Extract of Ginkgo biloba leaves attenuates kainate-induced increase in intracellular Ca²⁺ concentration of rat cerebellar granule neurons, Biological & Pharmaceutical Bulletin, Vol.28, No.5, 934-936, 2005. (Summary) イチョウ葉エキスがグルタミン酸興奮毒性を抑制する可能性をラット脳神経細胞にて証明した．これにより，イチョウ葉エキスは認知症(痴呆症)の予防には有効である可能性が示唆された． (Keyword) Animals / Calcium / Cells, Cultured / Cerebellum / Dose-Response Relationship, Drug / Ginkgo biloba / Intracellular Fluid / Kainic Acid / Neurons / Plant Extracts / Plant Leaves / Rats / Rats, Wistar (Link to Publication Site) ● Publication site (DOI): 10.1248/bpb.28.934 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15863911 ● Search Scopus @ Elsevier (PMID): 15863911 ● Search Scopus @ Elsevier (DOI): 10.1248/bpb.28.934 (DOI: 10.1248/bpb.28.934, PubMed: 15863911)
31.	Hiromi Nakao, Kaori Senokuchi, Chisato Umebayashi, Kaori Kanemaru, Toshiya Masuda, Yasuo Oyama and Shigetomo Yonemori : Cytotoxic activity of maytanprine isolated from Maytenus diversifolia in human leukemia K562 cells, Biological & Pharmaceutical Bulletin, Vol.27, No.8, 1236-1240, 2004. (Summary) We examined the cytotoxic effect of maytanprine isolated from the methanol extract of Maytenus diversifolia on human leukemia K562 cells using a flow cytometer and compared its cytotoxicity with that of maytansine, a potent cytotoxic maytansinoid. Maytanprine at concentrations of 0.03 nM or more (up to 1 nM) attenuated cell growth with decreasing cell viability and increased the population of shrunken cells in a concentration-dependent manner. Complete inhibition of growth by maytanprine was observed at concentrations of 0.3 nM or more. The compound at 0.03 nM markedly decreased the population at G0G1 phase in the cell cycle, but only slightly decreased that in the G2M phase, suggesting the possibility that it inhibits or delays cell division, and increased the population of cells with hypodiploidal DNA (apoptotic cells). The potency of maytanprine in inhibiting cell growth was greater than that of maytansine, although the inhibitory action of maytanprine was similar to that of maytansine. The results suggest that maytanprine exerts a potent inhibitory action on the growth of human leukemia K562 cells. M. diversifolia is one natural source of maytanprine, which is more cytotoxic than maytansine. (Keyword) Antineoplastic Agents / Cell Division / Flow Cytometry / Humans / K562 Cells / Maytansine (Link to Publication Site) ● Publication site (DOI): 10.1248/bpb.27.1236 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 15305028 ● Search Scopus @ Elsevier (PMID): 15305028 ● Search Scopus @ Elsevier (DOI): 10.1248/bpb.27.1236 (DOI: 10.1248/bpb.27.1236, PubMed: 15305028)
32.	Chisato Umebayashi, Natsuko Yamamoto, Hiromi Nakao, Yukiko Toi, Lumi Chikahisa-Muramatsu, Kaori Kanemaru, Toshiya Masuda and Yasuo Oyama : Flow cytometric estimation of cytotoxic activity of rhodexin A isolated from Rhodea japonica in human leukemia K562 cells, Biological & Pharmaceutical Bulletin, Vol.26, No.5, 627-630, 2003. (Keyword) rhodexin (Link to Publication Site) ● Publication site (DOI): 10.1248/bpb.26.627 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 12736502 ● Search Scopus @ Elsevier (PMID): 12736502 ● Search Scopus @ Elsevier (DOI): 10.1248/bpb.26.627 (DOI: 10.1248/bpb.26.627, PubMed: 12736502)
33.	Hiromi Hayashi, Hitomi Sakai, Wakako Minakuchi-Fijiwara, Miki Takayama, Michiko Nakamura-Murata, Yoshiko Kamo, Kanako Funakoshi, Keisuke Fukumoto, Kaori Kanemaru, Hideyuki Nakagawa, Yasuo Oyama, Nobuyuki Shinohara and Yoshihiro Ito : Cytokinesis arrest and nuclear fission in low density populations of Trichomonad Protozoan, Zoological Science, Vol.19, No.10, 1089-1094, 2002. (Summary) Cell growth of anaerobic protozoan Tritrichomonas foetus was analyzed. This protozoan usually proliferates in extremely high density, but protozoan parasites were dispersed uniformly in F-bouillon medium and cell division stopped temporarily. However, nuclear fission continued and giant polynucleated cells formed. Later, cell division resumed and cells returned to normal form. In conditioned medium, cytokinesis of the dispersed parasites did not stop. Results indicated that T. foetus cells secreted an extracellular factor that influenced cytokinesis. (Keyword) Animals / Cell Division / Cell Nucleus / Culture Media / Oxygen / Population Density / Time Factors / Trichomonas (Link to Publication Site) ● Publication site (DOI): 10.2108/zsj.19.1089 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 12426470 ● CiNii @ National Institute of Informatics (CRID): 1522825128326665984 ● Search Scopus @ Elsevier (PMID): 12426470 ● Search Scopus @ Elsevier (DOI): 10.2108/zsj.19.1089 (DOI: 10.2108/zsj.19.1089, PubMed: 12426470, CiNii: 1522825128326665984)
34.	Yoshihiko Okada, Yasuo Oyama, Lumi Chikahisa, Kaori Kanemaru, Hitomi Sakai, Katuhiko Noda and Masaya Satoh : Tri-n-butyltin-induced decrease in cellular level of glutathione in rat thymocytes: a flow cytometric study using 5-chloromethylfluorescein diacetate, Toxicology Letters, Vol.117, 123-128, 2000. (Keyword) tri-n-butyltin
35.	Yasuo Oyama, Sachi Noguchi, Mami Nakata, Yoshihiko Okada, Yuko Yamazaki, Megumi Funai, Lumi Chikahisa and Kaori Kanemaru : Exposure of rat thymocytes to hydrogen peroxide increases annexin-V binding to membranes: inhibitory action of deferoxamine and quercetin, European Journal of Pharmacology, Vol.384, 47-52, 1999. (Summary) 過酸化水素による酸化ストレスがカルシウムイオン依存性に細胞膜にアポトーシス様変化を起こさせることを明らかにした．実験にはラット胸腺細胞を用い，フローサイトメーターによりアネキシン結合，細胞膜透過性，細胞内カルシウムイオン濃度などの測定を行った．細胞内カルシウムイオン濃度の上昇に伴い，アネキシン結合(フォスファチジルセリン露出)が認められた．これらの実験から上記の結論を得た． (Keyword) oxidative stress
36.	Hideyuki Nakagawa, Chieko Yamaguchi, Hitomi Sakai, Kaori Kanemaru, Hiromi Hayashi, Yasutetsu Araki, Yasuhiro Tomihara, Mitsuko Shinohara, Kiyoshi Ohura and Hisato Kitagawa : Biochemical and physiological properties of pedicellarial lectins from the toxopneustid sea urchins, Journal of Natural Toxins, Vol.8, No.3, 297-308, 1999. (Summary) Pedicellarial lectins (SUL-I, SUL-II, and TGL-I) were purified from the toxopneustid sea urchins, Toxopneustes pileolus and Tripneustes gratilla using gel filtration chromatography, affinity chromatography, and reverse-phase HPLC. SUL-I (Nakagawa et al., 1996) and SUL-II from the large globiferous pedicellariae of T. pileolus are D-galactose-binding lectins with molecular masses of 32 kDa and 23 kDa, respectively; while TGL-I from the globiferous pedicellariae of T. gratilla is a Ca(2+)-independent heparin-binding lectin with a molecular mass of 23 kDa. SUL-I induced mitogenic stimulation on murine splenocytes but TGL-I did not. At higher dose ranges SUL-I exhibited inhibitory effects on the cells. The dual response to SUL-I was effectively inhibited by D-galactose. SUL-I enhanced norepinephrine-induced contraction of isolated rat mesenteric artery with endothelium. When endothelium was removed from the artery, acetylcholine did not relax the norepinephrine-induced contraction. In the same artery the enhancing effect of the contraction by SUL-I was abolished, suggesting that SUL-I acts on the endothelium of mesenteric artery, and may release prostanoids. The present results suggest an extracellular function for SUL-I that may have wide-ranging effects in physiological processes. The primary role of pedicellarial lectins from T. pileolus and T. gratilla might be defense against a foreign body. (Keyword) Toxopneustes pileolus / Toxopneustes gratilla / D-galactose-specific lectin / Heparin-specific lectin / Contraction (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 10591033 ● Search Scopus @ Elsevier (PMID): 10591033 (PubMed: 10591033)
37.	Yasuo Oyama, Lumi Chikahisa, Kaori Kanemaru, Mami Nakata, Sachi Noguchi, Takayuki Nagano, Eisuke Okazaki and Akira Hirata : Cytotoxic actions of FTY720, a novel immunosuppressant, on thymocytes and brain neurons dissociated from the rat, The Japanese Journal of Pharmacology, Vol.76, 377-385, 1998. (Keyword) FTY720
38.	Yasuo Oyama, Lumi Chikahisa, Toshiko Ueha, Kaori Kanemaru and Katuhiko Noda : Ginkgo biloba extract protects brain neurons aganist oxidative stress induced by hydrogen peroxide, Brain Research, Vol.712, No.2, 349-352, 1996. (Keyword) Ginkgo biloba
39.	Eisuke Okazaki, Lumi Chikahisa, Kaori Kanemaru and Yasuo Oyama : Flow cytometric analysis on the H₂O₂-induced increase in intracellular Ca²⁺ concentration of rat thymocytes, The Japanese Journal of Pharmacology, Vol.71, No.4, 273-280, 1996. (Keyword) hydrogen peroxide
40.	Kaori Kanemaru and 宮本悌次郎 : イソチオシアン酸アリルとその誘導体による細菌増殖阻害, 日本食品工業学会誌, Vol.38, No.10, 926-929, 1991.
41.	Kaori Kanemaru and Teijiro Miyamoto : Inhibitory effects on the growth of several bacteria by brown mustard and allyl isothiocyanate, Nippon Shokuhin Kogyo Gakkaishi, Vol.37, No.10, 823-829, 1990.
42.	Kaori Kanemaru, Tomohisa Takaya and Teijiro Miyamoto : Separation and quantitation of allyl isothiocyanate in brown mustard and cinnamaldehyde in cinnamon by reverse-phase high performance liquid chromatography, Nippon Shokuhin Kogyo Gakkaishi, Vol.37, No.7, 565-568, 1990.

Academic Paper (Unrefereed Paper):

1.	山口智美, 松家憲子, 先川正志, Kaori Kanemaru and 新居雅宏 : 乳酸菌発酵米飼料を活用した「阿波ポーク」生産技術の開発, 徳島県立農林水産総合技術支援センター畜産研究所研究報告, Vol.13, 27-30, 2014. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050282813732027520 (CiNii: 1050282813732027520)
2.	Hiroko Matsui, Yoko Sakanashi, Yumiko Nishimura, Kanna Horimoto, Kaori Kanemaru, Shiro Ishida, Yoshiro Okano and Yasuo Oyama : Cremophor EL modifies adriamycin-induced action on human leukemia K562 cells, Natural Science Research, Vol.21, 9-17, 2007. (Summary) Adriamycin and paclitaxel are simultaneously used for cancer treatment in some cases. The formula of paclitaxel contains cremophor EL as a solvent. Since this solvent exerts diverse biological actions, the modification of adriamycin action by cremophor EL has been studied on human leukemia K562 cells. Cremophor EL did not significantly affect the concentration-response relation for antiproliferative action of adriamycin and the cell cycle changed by adriamycin. However, the induction of morphological change induced by adriamycin was significantly augmented by cremophor EL. The simultaneous application of cremophor EL increased the intensity of fluorescence from adriamycin trapped inside the cells in a concentration-dependent manner, suggesting an increase in intracellular concentration of adriamycin by cremophor EL. Adriamycin alone at concentrations higher than those to completely inhibit the growth induced morphological change in K562 cells. Therefore, cremophor EL may potentiate some of actions induced by adriamycin when adriamycin and paclitaxel are simultaneously applied. (Keyword) adriamycin / adriamycin / cremophor EL / cremophor el / cytotoxicity / cytotoxicity / human leukemia K562 cells / human leukemia k562 cells (Tokushima University Institutional Repository) ● Metadata: 117529 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050293633442989056 (Tokushima University Institutional Repository: 117529, CiNii: 1050293633442989056)
3.	Masako Kobayashi, Yoko Sakanashi, Hiroko Matsui, Yumiko Nishimura, Kaori Kanemaru, Yoshiro Okano and Yasuo Oyama : Micromolar zinc modifies the cell death induced by clotrimazole in human leukemia K562 cells, Natural Science Research, Vol.21, 1-8, 2007. (Summary) Our recent study showed that the simultaneous application of clotrimazole with CdCl2 or PbCl2 exerted potent cytotoxic action in rat thymocytes although respective agents were ineffective. It was also the case of ZnCl2 and clotrimazole in preliminary study using rat thymocytes. Since clotrimazole is supposed to be a candidate for anticancer drug, we examined the effects of clotrimazole, ZnCl2, and their combination on human leukemia K562 cells. The combination of clotrimazole and ZnCl2 exerted potent cytotoxic effects on the growth and lethality of K562 cells by presumably modifying the process of cell death. The result suggests the possibility that endogenous Zn2+ may modify the action of clotrimazole. (Keyword) clotrimazole / clotrimazole / zinc / zinc / cytotoxicity / cytotoxicity / human leukemia K562 cells / human leukemia k562 cells (Tokushima University Institutional Repository) ● Metadata: 117528 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050856583396476800 (Tokushima University Institutional Repository: 117528, CiNii: 1050856583396476800)
4.	Katuhiko Noda, Kaori Kanemaru and Yasuo Oyama : レタス種子の生育に及ぼすナトリウムの影響, Natural Science Research, Faculty of Integrated Arts and Sciences, The University of Tokushima, Vol.17, 63-67, 2003.
5.	Hiromi Nakao, Yoshimi Narita, Lumi Chikahisa-Muramatu, Chisato Umebayashi, Kaori Kanemaru, Yasuo Oyama, Shiro Ishida and Okano Yoshiro : Further characterization of buthionine sulfoximine-induced potentiation of As2O3 cytotoxicity in human leukemia K562 cells: a flow cytometric study, Natural Science Research, Vol.17, 27-41, 2003.
6.	Yoshimi Narita, Yasuo Oyama, Tomohiro Arata, Kaori Kanemaru and Yoshiro Okano : Potentiation of As2O3-induced cytotoxicity by buthionine sulfoximine in human leukemia K562 cells, Natural Science Research, Vol.15, 21-34, 2002. (Keyword) arsenic trioxide
7.	Noriko Kajita, Lumi Chikahisa, Yuko Yamazaki, Norihiko Akaike, Kaori Kanemaru, Hitomi Sakai, Katuhiko Noda and Yasuo Oyama : Effects of the agents affecting membrane potassium permeability on growth and viability in human leukemia K562 cells, Natural Science Research, Vol.14, 35-46, 2001. (Keyword) potassium permeability
8.	Yoshihiko Okada, Yasuo Oyama, Toshiko Ueha-Ishibashi, Kaori Kanemaru, Norihiko Akaike, Norikazu Miyoshi and Masaya Satoh : Cytotoxic action of tri-n-butyltin hydride, a nucleaphilic triorganotin, on rat thymocytes: a flow cytometric study, Natural Science Research, Vol.14, 21-34, 2001. (Keyword) tri-n-butyltin
9.	Yasuo Oyama, Yoshihiko Okada, Norihiko Akaike, Kaori Kanemaru, Yumiko Kanemoto, Lumi Chikahisa, Masaya Satoh and Hiromi Hayashi : Protective action of tri-n-butyltin on the cells suffering from oxidative strss: Its implication in bioaccumulation, Natural Science Research, Vol.14, 9-20, 2001. (Keyword) tri-n-butyltin
10.	野田克彦 and Kaori Kanemaru : 心拍数を目安とした心肺機能の測定, 徳島大学総合科学部自然科学研究, Vol.13, 15-18, 2000.
11.	野田克彦, Kaori Kanemaru and 小宮山朋子 : 簡易な方法で得られる体脂肪率と骨振動数の関連について, 徳島大学総合科学部自然科学研究, Vol.12, 9-14, 1999.
12.	Kaori Kanemaru, Yasuo Oyama, Lumi Chikahisa, Mami Nakata, Takayuki Nagano, Eisuke Okazaki, Katuhiko Noda and Toshiya Masuda : Protection of brain neuronss suffering from oxidative stress by new curcuminoids isolated from Zingiber cassumunar, Natural Science Research, Vol.11, 7-19, 1998. (Keyword) antioxidant
13.	Kaori Kanemaru, 藤原和子 and 宮本悌次郎 : 市販粉ワサビと数種化合物併用による細菌増殖阻害作用, 大阪市立大学生活科学部紀要, Vol.37, 9-13, 1989.
14.	Kaori Kanemaru, 高谷友久 and 宮本悌次郎 : 市販粉ワサビ，カラシ粉の細菌増殖阻害作用, 大阪市立大学生活科学部紀要, Vol.37, 1-7, 1989.
15.	田邊幾之助 and Kaori Kanemaru : 旧式焼酎の高酸度醪のモデル実験について, 鹿児島大学農学部学術報告, Vol.36, 99-109, 1986.
16.	田邊幾之助, 二石大介 and Kaori Kanemaru : 旧式焼酎酒母・醪から分離した乳酸菌の生態学的性質について, 鹿児島大学農学部学術報告, Vol.34, 45-57, 1986.
17.	田邊幾之助, 有川順子, Kaori Kanemaru, 丸山智之 and 佐藤平二 : 高酸度焼酎醪における乳酸菌の蛍光抗体法による検出について, 鹿児島大学農学部学術報告, Vol.33, 53-63, 1983.

Academic Letter:

1.	Shoehei Saitoh, Eri Fukunaga, Sari Honda, Kaori Kanemaru, Masaya Satoh and Yasuo Oyama : Nonivamide, a natural analog of capsaicin, affects intracellular Ca2+ level in rat thymic lymphocytes, Natural Science Research, Vol.28, No.3, 15-19, 2014. (Summary) Effect of nonivamide, a natural analog of capsaicin, on intracellular Ca2+ level of rat thymocytes was examined using a flow-cytometric technique with appropriate fluorescent probes in order to further characterize the cytotoxicity because nonivamide can be used as an active intergradient of antifouling paints. Nonivamide at concentrations ranging from 30 µM to 300 µM significantly increased the intensity of Fluo-3 fluorescence. The potency of 100 µM nonivamide to increase the fluorescence was similar to that of 100 µM capsaicin. The increase in Fluo-3 fluorescence by 100 µM nonivamide was attenuated under an external Ca2+-free condition. Nonivamide at 100 µM also increased the intensity of Fluo-3 fluorescence in the continued presence of 100 µM capsaicin. It is suggested that nonivamide at high micromolar concentrations increases intracellular Ca2+ level via the activation of vanilloid receptors. Nonivamide concentrations (30 µM or more) that increase intracellular Ca2+ level in rat thymocytes are comparable to those in algal cells. However, it is something hard to argue the implications in environmental science because nonivamide doesn't seem to be released into environment in such a high concentration, and because bioaccumulation of nonivamide has not been reported. (Keyword) Capsaicin / Nonivamide (Tokushima University Institutional Repository) ● Metadata: 106432 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050564287418356224 (Tokushima University Institutional Repository: 106432, CiNii: 1050564287418356224)

Review, Commentary:

1.	Kaori Kanemaru and Kumio Yokoigawa : 大腸菌の食品加工・調理器具素材への付着とバイオフィルム形成, Clean Technology, Vol.28, No.8, 19-21, Aug. 2018. (Keyword) Escherichia coli / biofilm (Tokushima University Institutional Repository) ● Metadata: 113898 (Tokushima University Institutional Repository: 113898)
2.	Kaori Kanemaru, Makiko Tsuji and Kumio Yokoigawa : 食品加工・調理器具への微生物の付着と殺菌剤耐性, 食品機械装置, Vol.53, No.10, 50-55, Oct. 2016. (Tokushima University Institutional Repository) ● Metadata: 113902 (Tokushima University Institutional Repository: 113902)

Proceeding of International Conference:

1.	Takahashi Keiko, Matsushita Junko, Ofuku Tsukie, Endo Chizuru, Kaori Kanemaru, Ariuchi Naoko and Tamura Sakie : A Study of Fish-Intake Situation in Tokushima Prefecture, IFHI 2004 Post-Congress on Japanese Food Culture, 65-66, Aug. 2004.
2.	Mtsushita Fumiko, Itakura Kazue, Yokoyama Yae, Ishikawa Yukihiro, Tsunomori Akiko, Nagata Kimiko, Okuno Motoko, Yamamoto Yoshihiro, Esumi Yukiko, Ando Mami, Sakurahi Nahoko, Hanai Reiko, Koda Tomoko, Goto Yoshiko, Kamei Aya, Tuchiya Fusae, Okuda Hiroe, Maeda HIromi, Ohshita Ichiko, Okuyama Kiyomi, Kurata Mie, Miyoshi Yasuyuki, Okamoto Yoko, Kamimura Yoshie, Ikawa Yoshiko, Teramoto Ai, Sasaki Atsuko, Ohno Fumiko, Fujii Kumiko, Takada Marhiko, Fuchigami Michiko, Wada Haruko, Aoki MIeko, Hirano Naoko, Imada Setsuko, Nishizaki Sumiyo, Arimoto Shouzou, Arita Taeko, Hitomi Tetsuko, Kasai Yaeko, Fujii Wakako, Kato Miyuki, Kawasome Setsue, Akiyama Teruko, Udaka Junko, Mine Hiroko, Takeda Tamami, Kawabata Kazuko, Shigematu Kumi, Uyama Hiroko, Kaori Kanemaru, Tamura Sakie, Shibayama Kiyoko and Morioka Miho : The Dietary Habit of Soybeans and their Processed Products in the Chugoku and the Shikoku Areas -A Comparison between the Early Showa Era and the Present-, IFHE 2004 Post-Congress on Japanese Food Culture, 29-30, Aug. 2004.
3.	Hideyuki Nakagawa, Hitomi Sakai, Kaori Kanemaru and Hiromi Hayashi : A sea urchin lectin, SUL-I induces differentiation on murine myeloid leukemic cells, GRC on Marine Natural Products, Ventura, California, Feb. 2004. (Summary) ラッパウニ叉棘から精製されたD-galactose binding lectin のSUL-I はマウス由来のmyeloid leikemic cell をマクロファージ様に分化誘導し，部分的なアポトーシスを引き起こした． (Keyword) murine myeloid cells / differentiation / D-galatose-binding lectin / sea urchin lectin / Toxopneustes pileolus

Proceeding of Domestic Conference:

1.	山﨑義輝, 山下晶央, Chizuru Sasaki, Junji Hayashi, Ryushi Kawakami and Kaori Kanemaru : 鳴門産スジアオノリ(Ulva prolifera)の志賀毒素吸着活性, 日本農芸化学会中四国支部第64 回講演会要旨集, Jan. 2023. (Keyword) E. coli O157 / Siga Toxin / Ulva prolifera / adsorption
2.	山下晶央, 山﨑義輝, Chizuru Sasaki, Junji Hayashi, Ryushi Kawakami and Kaori Kanemaru : アラメ(Eisenia bicyclis)によるEHEC O157 産生志賀毒素吸着, 日本農芸化学会中四国支部大会講演要旨集, 37, Sep. 2022. (Keyword) E. coli O157 / Siga Toxin / Eisenia bicyclis / adsorption
3.	Chizuru Sasaki, 新居美香, Junji Hayashi and Kaori Kanemaru : ワカメ非可食部の資源化を目的とした連続水熱処理による有用物質生産法の開発, 日本食品工学会2022年度大会, 岡山, Sep. 2022.
4.	三木章江, 高橋啓子, 後藤月江, 川端紗也花, 長尾久美子, 松下純子, 坂井真奈美, 近藤美樹 and Kaori Kanemaru : Tokushima Prefecture home cooking: local characteristics Local dishes familiar in Tokushima, 日本調理科学会2022年度大会研究発表要旨集, Sep. 2022. (Keyword) 徳島 / 家庭料理 / 主食・主菜・副菜・汁物・おやつ
5.	Rumana Yesmin Hasi, Naohiro Imura, Toshiki Ishikawa, Hiroyuki Imai, Yoshimichi Takai, Hanif Ali, Mutsumi Aihara, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru and Tamotsu Tanaka : Distribution and characterization of glycosylinositol phosphoceramide specific phospholipase D in Brassica plants, 第64回日本脂質生化学会, Vol.64, 272-275, Jun. 2022.
6.	Hanif Ali, Miyu Kobayashi, Katsuya Morito, Rumana Yesmin Hasi, Mutsumi Aihara, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, Koichiro Tsuchiya, Kazunori Sango and Tamotsu Tanaka : Peroxisomes attenuate lipotoxicity of very-long-chain fatty acids, 第64回日本脂質生化学会, Vol.64, 43-46, Jun. 2022.
7.	Hanif Ali, Miyu Kobayashi, Katsuya Morito, Rumana Yesmin Hasi, Mutsumi Aihara, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, Koichiro Tsuchiya, Kazunori Sango and Tamotsu Tanaka : Metabolism and biological effect of very-long-chain fatty acid in peroxisome-deficient cells, 第63回日本生化学中国・四国支部例会, May 2022.
8.	Hanif Ali, Katsuya Morito, Rumana Yesmin Hasi, Mutsumi Aihara, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, Koichiro Tsuchiya, Kazunori Sango and Tamotsu Tanaka : Characterization of uptake and metabolism of very-long-chain fatty acid in peroxisome-deficient CHO cells, 第94回日本生化学大会, Nov. 2021.
9.	Rumana Yesmin Hasi, Naohiro Imura, Toshiki Ishikawa, Hiroyuki Imai, Yoshimichi Takai, Hanif Ali, Mutsumi Aihara, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru and Tamotsu Tanaka : Production of phytoceramide 1- phosphate and inositol glycan by glycosylinositol phosphoceramide specific phospholipase D activity in plants, 第94回日本生化学大会, Nov. 2021.
10.	Hanif Ali, Katsuya Morito, Rumana Yesmin Hasi, Mutsumi Aihara, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, Koichiro Tsuchiya, Kazunori Sango and Tamotsu Tanaka : Characterization of uptake and metabolism of very-long-chain fatty acid in peroxisome-deficient CHO cells, 第62回日本生化学中国・四国支部例会, Sep. 2021.
11.	Rumana Yesmin Hasi, Naohiro Imura, Toshiki Ishikawa, Hiroyuki Imai, Yoshimichi Takai, Hanif Ali, Mutsumi Aihara, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru and Tamotsu Tanaka : Production of phytoceramide 1- phosphate and inositol glycan by glycosylinositol phosphoceramide specific phospholipase D activity in plants, 第62回日本生化学中国・四国支部例会, Sep. 2021.
12.	高橋啓子, 三木章江, 宇野美和子, 川端紗也花, 後藤月江, 長尾久美子, 松下純子, 近藤美樹, 坂井真奈美 and Kaori Kanemaru : 徳島県の家庭料理行事食の特徴 -ひな祭りの楽しい思い出-遊山箱―, 日本調理科学会2021年度大会, Sep. 2021.
13.	Hanif Ali, Katsuya Morito, Rumana Yesmin Hasi, Mutsumi Aihara, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, Koichiro Tsuchiya and Tamotsu Tanaka : Uptake and metabolism of very-long-chain fatty acid in animal cells, 第63回日本脂質生化学会, Jun. 2021.
14.	Rumana Yesmin Hasi, Yoshimichi Takai, Hanif Ali, Kentaro Kogure, Junji Hayashi, Ryushi Kawakami, Mutsumi Aihara, Kaori Kanemaru and Tamotsu Tanaka : Isolation of glycosylinositol phosphoceramide and phytoceramide 1-phosphate from cabbage leaves and their chemical stabilities., 日本農芸化学会2020年度中四国支部大会(第57回講演会), Sep. 2020.
15.	YAMASHITA Akio, YAMASAKI Yoshiki and Kaori Kanemaru : STEC O157:H7 産生志賀毒素の分離と細胞毒性, 日本農芸化学会2020年度中四国支部大会, 40, Sep. 2020.
16.	YAMASAKI Yoshiki, YAMASHITA Akio and Kaori Kanemaru : 固定化グルタミン酸(Glutamate-Sepharose)の志賀毒素吸着, 日本農芸化学会2020年度中四国支部大会, 40, Sep. 2020.
17.	Rumana Yesmin Hasi, Dai Majima, Katsuya Morito, Hanif Ali, Kentaro Kogure, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, Meera Nanjundan, Toshiki Ishikawa and Tamotsu Tanaka : Methods for isolation of glycosylinositol phosphoceramide and phytoceramide 1-phosphate from plant tissues., 第93回日本生化学大会, Sep. 2020.
18.	Rumana Yesmin Hasi, Dai Majima, Katsuya Morito, Hanif Ali, Kentaro Kogure, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, Meera Nanjundan, Toshiki Ishikawa, Hiroyuki Imai and Tamotsu Tanaka : Development of methods for isolation of glycosylinositol phosphoceramide and phytoceramide 1-phosphate from plant tissues., 第62回日本脂質生化学会, May 2020.
19.	Kaori Kanemaru : ポリ-γ-グルタミン酸の志賀毒素吸着と CACO-2細胞への影響, 第40回日本食品微生物学会学術総会講演要旨集, Nov. 2019.
20.	Tamotsu Tanaka, Rumana Yesmin Hasi, Katsuya Morito, Kentaro Kogure, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, 今井博之 and 石川寿樹 : グリコシルイノシトールホスホセラミドの単離法の開発, 第12回セラミド研究会学術集会, Oct. 2019.
21.	Tamotsu Tanaka, Katsuya Morito, Rumana Yesmin Hasi, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, 若山睦, 近藤千恵子, Tatsuya Fukuta and Kentaro Kogure : 食品素材に含まれるセラミドの簡便な定量方法, 日本脂質栄養学会第28回大会, Sep. 2019.
22.	長尾久美子, 坂井真奈美, 松下純子, 近藤美樹, 後藤月江, 三木章江, 高橋啓子, 川端沙也花 and Kaori Kanemaru : 徳島県の家庭料理副菜の特徴∼食材から見える地域性∼, 日本調理科学会2019年度大会研究発表要旨集, Aug. 2019.
23.	Hitomi Sakai, Kaori Kanemaru, Tohru Sakai and Kumio Yokoigawa : 調理器具素材への大腸菌の付着を抑制する小麦粉の成分の同定, 第39回日本食品微生物学会総会, Sep. 2018.
24.	Kaori Kanemaru, Hitomi Sakai, Keiko Takahashi and Kumio Yokoigawa : ガラス表面に付着した大腸菌の洗浄と殺菌, 第39回日本食品微生物学会学術総会講演要旨集, 111, Sep. 2018. (Keyword) biofilm / Escherichia coli
25.	丸谷永一, Kaori Kanemaru, 清水正明 and 藤本武 : 徳島県産「タデ藍」を活用した鶏肉商品価値を高める魚粉飼料給与技術の確立, 平成30年度第68回関西畜産学会大会(徳島大会)講演要旨集, 15, Sep. 2018.
26.	Kaori Kanemaru, 坂井真奈美, 松下純子, 長尾久美子, 近藤美樹, 後藤月江, 三木章江, 川端紗也花 and 髙橋啓子 : 徳島県の家庭料理主菜の特徴地場食材を用いた主菜, 一般社団法人日本調理科学会平成30年度大会，西宮研究発表要旨集, 97, Aug. 2018.
27.	Ryushi Kawakami, Kaori Kanemaru and Kumio Yokoigawa : 食品微生物や発酵食品に含まれるD-アミノ酸検出のためのUHPLC検出系の構築, 第38回日本日本食品微生物学会学術総会, Oct. 2017.
28.	Badr Ali Hoida, Takahashi Keiko, Ryushi Kawakami, Yasuo Oyama, Kumio Yokoigawa and Kaori Kanemaru : Screening and analysis of edible seaweeds in the ability to adsorb Shiga toxin, 第38回日本日本食品微生物学会学術総会, Oct. 2017.
29.	Tsukie Goto, Kaori Kanemaru and Kumio Yokoigawa : 固定化ポリーγーグルタミン酸の志賀毒素吸着性, 第38回日本食品微生物学会学術総会, Oct. 2017.
30.	後藤月江, 三木章江, 川端沙也花, 高橋啓子, 坂井真奈美, 松下純子, 長尾久美子, 近藤美樹 and Kaori Kanemaru : 徳島県の家庭料理おやつの特徴ー地域で親しまれてきたおやつ-, 日本調理科学会平成29年度大会研究発表要旨集, 101, Aug. 2017.
31.	生杉笙, Kaori Kanemaru, Kumio Yokoigawa and Yasuo Oyama : 徳島県産食用植物クサギClerodendrum trichotomunのガン細胞増殖抑制, 日本農芸化学会中国四国支部第48回講演会講演要旨, 33, Jun. 2017.
32.	Kumio Yokoigawa, 高橋啓子 and Kaori Kanemaru : 非生物素材に付着した大腸菌O157のバイオフィルム形成, 日本農芸化学会2017大会, Mar. 2017.
33.	Kaori Kanemaru, 生杉笙, Ryushi Kawakami, Yasuo Oyama and Kumio Yokoigawa : 徳島県産食用植物のガン細胞増殖抑制, 日本農芸化学会2017年度(平成29年度)大会講演要旨集, Mar. 2017.
34.	Kumio Yokoigawa, オワイダアリバドル and Kaori Kanemaru : 食用海藻の志賀毒素吸着性, 第37回日本食品微生物学会学術総会講演要旨集, 64, Sep. 2016.
35.	後藤月江, 逵牧子, Kaori Kanemaru and Kumio Yokoigawa : 沈殿したポリ-γ-グルタミン酸の志賀毒素吸着性, 日本農芸化学会中四国支部第45回講演会要旨集, 24, Jun. 2016.
36.	高橋啓子, Takefumi Hattori, Kaori Kanemaru, Yasuo Oyama and Kumio Yokoigawa : Tricholoma matsutake 菌糸生育におけるD-及びL-アミノ酸の添加効果, 日本農芸化学会中四国支部第45回講演会要旨集, 36, Jun. 2016.
37.	Badr Ali Hoida, Kaori Kanemaru and Kumio Yokoigawa : Screening and analysis of edible seaweeds in the ability to adsorb Shiga toxin, 日本農芸化学会中四国支部第45回講演会要旨集, 23, Jun. 2016.
38.	Kaori Kanemaru, 高橋啓子, 後藤月江, 三木章江, 長尾久美子, 近藤美樹 and 松下純子 : 次世代に伝え継ぐ日本の家庭料理ー徳島県の聞き書き調査から・おかずー, 一般社団法人日本調理科学会平成27年度大会研究発表要旨集, 28, Aug. 2015.
39.	高橋啓子, 後藤月江, 三木章江, Kaori Kanemaru, 長尾久美子, 近藤美樹 and 松下純子 : 次世代に伝え継ぐ日本の家庭料理ー徳島県の聞き書き調査からー, 一般社団法人日本調理科学会平成26年度大会研究発表要旨集, 86, Aug. 2014.
40.	松家憲子, 山口智美, 葵義民, 三枝貴代 and Kaori Kanemaru : 乳酸菌発酵米の肥育豚に対する給与効果の検討, 第63回四国地区獣医師大会・平成24年度獣医学術四国地区学会・日本産業動物学会(四国)・日本小動物学会(四国)・日本獣医公衆衛生学会(四国), Sep. 2012.
41.	Kaori Kanemaru, 遠藤千鶴, 高橋啓子, 松下純子, 後藤月江, 武田珠美, 長尾久美子 and 有内尚子 : 徳島県における行事食・儀礼食の現状について –地域別比較-, 日本調理科学会平成24年度大会, Aug. 2012.
42.	松下純子, 武田珠美, 後藤月江, 遠藤千鶴, 高橋啓子, 有内尚子, 長尾久美子 and Kaori Kanemaru : 徳島県における行事食の現状について(2) 人日から大みそかおよび春祭り・秋祭り(正月を除く), 日本調理科学会平成23年度大会, Aug. 2011.
43.	高橋啓子, Kaori Kanemaru, 後藤月江, 遠藤千鶴, 有内尚子, 長尾久美子, 松下純子 and 武田珠美 : 徳島県の行事食の現状についてー正月料理・通過儀礼ー, 日本調理科学会平成23年度大会, Aug. 2011.
44.	松浦(三木) 宏美, Kaori Kanemaru, 山本済人 and 岩田深也 : 鳴門金時(Ipomoea batatas)茎葉部の食品機能性, 日本農芸化学会中四国支部第22回講演会(2008年度支部大会)講演要旨集, 39, Sep. 2008.
45.	三木宏美, 田中芙美佳, Kaori Kanemaru, 山本澄人, 岩田深也, 柏岡静, 阿佐章, 田中道夫, 近藤雅勝, 坂東弘康 and 大田昌平 : SKゴールド(飼料混合用納豆菌製剤)の機能性, 日本農芸化学会中四国支部第20回講演会講演要旨集, 29, Jan. 2008.
46.	Kaori Kanemaru, 三木宏美, 井田貴子, 山本澄人, 岩田深也, 有井俊介 and 仲野孝弘 : 鳴門金時の食品機能性, 日本農芸化学会2007年度中四国・西日本支部合同大会講演要旨集, 45, Sep. 2007.
47.	Kaori Kanemaru, 三木宏美, 井田貴子, 松本哲治, 林弘三 and 小山保夫 : カフェ酸とクロロゲン酸の機能性の比較, 49, Sep. 2006.
48.	杉本眞由美, 中川秀幸, 林弘三, 小山保夫, 増田俊哉 and Kaori Kanemaru : ヒジキのガン細胞増殖抑制, 日本農芸化学会2005年度関西・中四国・西日本支部合同大会講演要旨集, 38, Sep. 2005.
49.	高橋啓子, 松下純子, 後藤月江, 遠藤千鶴, Kaori Kanemaru, 有内尚子 and 田村咲江 : 徳島県における魚食の現状, 89, Sep. 2005.
50.	Kaori Kanemaru, 杉本眞由美, 横井川久己男, 山本澄人, 岩田深也, 柏岡静, 阿佐章, 板東弘康 and 大田昌平 : 納豆菌発酵オカラの機能性, 日本食品科学工学会第52回大会講演集, 123, Aug. 2005.
51.	國永真妃, Kaori Kanemaru, 小山保夫, 酒井仁美, 中川秀幸 and 林弘三 : 香辛料成分によるマウスメラノーマに対する増殖抑制, 2004年度日本農芸化学会中国四国支部大会講演要旨集, 19, Sep. 2004.
52.	Hideyuki Nakagawa, Fumihiko Satoh, Yuuko Aguro, Takeshi Hosotani, Ai Yukata, Kaori Kanemaru, Kuniko Nagasaka, Toshinori Nagasaka, Mitsuko Shinohara, Tadashige Nozaki and Kiyoshi Ohura : Purification of a dorsal lectin from the redfin velvetfish, Hypodytes rubripinnis, Journal of Pharmacological Sciences, Vol.94, No.Supplement 1, 135p, Mar. 2004. (Summary) A novel lectin was isolated from the dorsal venom of H. rubripinnis by affinity chromatography and tested for mitogenicity. It showed a single protein band with a molecular mass of 120 kDa.
53.	Yuya Sasayama, Kaori Kanemaru, Yasuo Oyama and Hiromi Hayashi : シンナムアルデヒドのガン細胞増殖抑制, 平成15年度日本農芸化学会西日本支部，中四国支部．日本栄養·食糧学会西日本支部，日本食品科学工学会西日本支部鹿児島合同大会およびシンポジウム, Sep. 2003. (Keyword) Growth inhibition / Cancer cell / Cinnamaldehyde
54.	Kaori Kanemaru, Aki Fukuda, Hideyuki Nakagawa, Hiromi Hayashi, Katuhiko Noda and Yasuo Oyama : カフェ酸類似体の細胞保護作用とDPPHラジカル消去活性との比較, 日本農芸化学会2003年度大会, Apr. 2003.
55.	Kaori Kanemaru, 津田貴美 and 谷本桃代 : 香辛料成分によるガン細胞増殖阻害, 日本農芸化学会2002年度中四国支部大会講演要旨集, 54, Sep. 2002.
56.	Kaori Kanemaru, Momoyo Tanimoto, Kimi Tuda, Hideyuki Nakagawa, Hiromi Hayashi, Katuhiko Noda, Toshiya Masuda and Yasuo Oyama : H2O2傷害に対するカフェ酸の胸腺細胞保護作用, 日本農芸化学会2002年度大会, Mar. 2002.
57.	Kaori Kanemaru, Hideyuki Nakagawa, Hiromi Hayashi, Katuhiko Noda, Yasuo Oyama and Toshiya Masuda : 食品由来成分の細胞に対する生理機能作用, 日本農芸化学会2001年度関西·中国·四国支部合同大会, Oct. 2001.
58.	Kaori Kanemaru, Kuno Ryoko, Konishi Yukari, Sakai Hitomi, Yasuo Oyama, Hideyuki Nakagawa, Hiromi Hayashi and Katuhiko Noda : H2O2障害に対するヒジキの胸腺細胞保護作用, 日本食品科学工学会第48回大会, Sep. 2001.
59.	Kaori Kanemaru, Konishi Yukari, Kuno Ryoko, Satoh Masaya, Yasuo Oyama, Hayashi Hiromi, Sakai Hitomi, Nakagawa Hideyuki and Noda Katuhiko : ガン細胞増殖抑制活性を有する海藻の検索, 日本農芸化学会2001年度大会, Mar. 2001.
60.	Kaori Kanemaru, Ochi Miki, Kudaki Yosiko and Satoh Masaya : 海藻によるガン細胞増殖阻害作用, 日本農芸化学会2000年度大会, Apr. 2000.
61.	小山保夫, 山崎優子, 船井めぐみ, 岡田栄彦 and Kaori Kanemaru : ラット胸腺細胞に対するトリブチル錫の及ぼす影響-アネキシン V-FITCとエチジウムを用いる細胞毒性評価-, 日本薬理雑誌(第52回日本薬理学会西南支部会), Vol.115, No.3, Nov. 1999.
62.	中川秀幸, 沖田健宏, 酒井仁美, Kaori Kanemaru and 林弘三 : ウニ叉棘レクチンのマイトジェン活性と細胞障害性, 生化学(第72回日本生化学会大会発表抄録集), Vol.71, No.8, 846, Oct. 1999.
63.	Masaya Satoh, Keiko Funo, Sinsuke Yamazaki and Kaori Kanemaru : ストレス処理により分泌される褐藻類ヒジキの生理活性物質について, 日本植物学会第63回大会, Oct. 1999.
64.	Masaya Satoh, Keiko Funo, Mamiko Kakehashi, Emi Karaki and Kaori Kanemaru : 褐藻類ヒジキにおけるストレス処理による分泌物の性質について, 日本藻類学会第23回大会, Mar. 1999.
65.	Yasuo Oyama, 梶田紀子, 中田真美, 山崎優子, 船井めぐみ, 野口さち, Kaori Kanemaru and 近久ルミ : バリノマイシンのK562細胞増殖抑制作用, 日本薬理学雑誌(第51回日本薬理学会西南部会), Vol.113, No.3, 68, Nov. 1998.
66.	Kaori Kanemaru : 香辛料の細胞保護作用ならびにガン細胞および細菌増殖阻害作用, 第13回日本香辛料研究会, Nov. 1998.
67.	Kaori Kanemaru, Shibata Mamiko, Suzuki Emi, Tomiyoshi Fukiyo, (名) Katuhiko and Oyama Yasuo : 香辛料によるガン細胞増殖阻害作用, 第52回日本栄養·食糧学会大会, Apr. 1998.
68.	Kaori Kanemaru, Suzuki Emi, Shibata Mamiko, Hiromi Hayashi, Katuhiko Noda and Yasuo Oyama : 酸化ストレスに対する香辛料の細胞保護作用, 日本農芸化学会1998年度大会, Apr. 1998.
69.	Yasuo Oyama, 中田真美, 梶田紀子, 近久ルミ, 岡崎英佐, Kaori Kanemaru and Toshiya Masuda : 新規クルクミノイドの酸化ストレスに対する細胞保護作用, 日本薬理学雑誌(第50回日本薬理学会西南部会), Vol.111, No.2, 83, Nov. 1997.
70.	中川秀幸, 山口知栄子, Kaori Kanemaru, 林弘三, 富原靖博 and 新城安哲 : ウニ類の毒棘および叉棘レクチンによるマイトジェン活性, 111, Oct. 1996.
71.	富吉冨貴代, Kaori Kanemaru, 林弘三 and 大橋真 : 低蛋白食投与マウスのPlasmodium berghei感染抵抗性と免疫担当細胞の変動, 第47回日本栄養・食糧学会総会講演要旨集, 204, May 1993.
72.	富吉冨貴代, Kaori Kanemaru, 大橋真, 林弘三, 喜来伸江 and 山下正恵 : マウスのPlasmodium bergheiに対する抵抗性への飼料タンパク質量の影響, 第25回日本栄養・食糧学会中国・四国支部大会抄録集, 14, Nov. 1992.
73.	Kaori Kanemaru : クローブによる数種糸状菌の増殖抑制とそれに及ぼす水分活性の影響, 第25回日本栄養・食糧学会中国・四国支部大会抄録集, 11, Nov. 1992.
74.	Kaori Kanemaru, 枡本有紀子 and 宮本悌次郎 : ブラウンマスタードと酢酸併用時の食品中微生物増殖阻害, 日本食品工業学会第39回大会講演集, 100, Mar. 1992.
75.	Kaori Kanemaru, 渡邊容子 and 宮本悌次郎 : 香辛料による糸状菌の増殖抑制とそれに及ぼす湿度の影響, 日本調理科学会平成3年度大会研究発表要旨集, 15, Sep. 1991.
76.	Kaori Kanemaru, 南佳子 and 宮本悌次郎 : ブラウンマスタードの数種食品中の微生物増殖阻害, 第45回日本栄養・食糧学会総会講演要旨集, 36, May 1991.
77.	川島文恵, Kaori Kanemaru and 宮本悌次郎 : Allylisothiocyanateの細菌増殖阻害に及ぼす食品成分の影響, 日本食品工業学会第38回大会講演集, 137, Mar. 1991.
78.	Kaori Kanemaru, 熊村信美 and 宮本悌次郎 : クローブおよびマスタードの鶏レバー中微生物増殖抑制, 第44回日本栄養・食糧学会総会講演要旨集, 227, May 1990.
79.	Kaori Kanemaru, 藤井玲子, 高谷友久 and 宮本悌次郎 : クローブによる細菌プロテアーゼ阻害, 日本農芸化学会誌 (日本農芸化学会1990年度大会講演要旨集p.233), Vol.64, No.3, 541, Mar. 1990.
80.	Kaori Kanemaru, 辻本順子 and 宮本悌次郎 : ブラウンマスタードとアリルイソチオシアネートの微生物増殖阻害作用, 日本食品工業学会第36回大会講演集, 96, May 1989.
81.	Kaori Kanemaru, 森田恵都子 and 宮本悌次郎 : 香辛料添加による食品中の細菌増殖阻害作用, 第43回日本栄養・食糧学会総会講演要旨集, 128, May 1989.
82.	Kaori Kanemaru, 藤原和子, 高谷友久 and 宮本悌次郎 : ブラウンマスタードの細菌増殖阻害, 日本農芸化学会昭和63年度大会講演要旨集, 441, Apr. 1988.
83.	Kaori Kanemaru, 高谷友久 and 宮本悌次郎 : ワサビ，カラシ及びシナモンの細菌増殖阻害, 日本農芸化学会昭和62年度大会講演要旨集, 550, Apr. 1987.
84.	Kaori Kanemaru, 高谷友久 and 宮本悌次郎 : スパイスの精油主成分定量法の検討と細菌増殖阻害作用, 日本農芸化学会昭和61年度大会講演要旨集, 6, Nov. 1986.
85.	Kaori Kanemaru, 高谷友久 and 宮本悌次郎 : スパイス類とその成分の細菌増殖阻害, 日本農芸化学会昭和61年度大会講演要旨集, 576, Apr. 1986.
86.	Kaori Kanemaru and 宮本悌次郎 : スパイス類の細菌増殖阻害, 日本農芸化学会昭和60年度大会講演要旨集, 90, Jul. 1985.
87.	田邊幾之助, Kaori Kanemaru and 二石大介 : 高酸度焼酎醪のモデル実験としての乳酸菌と酵母の混合培養, 日本農芸化学会誌, Vol.57, No.12, 103, 1983.

Report:

1.	高橋啓子, Kaori Kanemaru, 後藤月江, 松下純子, 長尾久美子, 近藤美樹 and 三木章江 : 特別研究平成24∼25年度『次世代に伝え継ぐ日本の家庭料理』聞き書き調査報告 36. 徳島県, 平成24∼25年度『次世代に伝え継ぐ日本の家庭料理』聞き書き調査報告書, 421-429, Jun. 2014.
2.	松家憲子, 山口智美, 堀北直樹, 先川正志, Kaori Kanemaru and 新居雅宏 : 乳酸菌発酵飼料米を利用したプロバイオティクス飼料の開発, 徳島県立農林水産総合技術支援センター畜産研究所研究報告, Vol.12, No.12, 23-30, Mar. 2013. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050845763683961216 (CiNii: 1050845763683961216)
3.	Kaori Kanemaru, 後藤月江, 松下純子, 高橋啓子, 遠藤千鶴, 武田珠美, 長尾久美子 and 有内尚子 : 徳島県における行事食・儀礼食の現状, 日本調理科学会中国・四国支部創立40周年記念誌, 52-55, 2013.
4.	遠藤千鶴, 高橋啓子, 後藤月江, 有内尚子, 松下純子, 長尾久美子, 武田珠美 and Kaori Kanemaru : 平成22年度調理科学会特別研究「行事食・儀礼食」調査報告(徳島県), 平成21∼23年度日本調理科学会特別研究「調理文化の地域性と調理科学」報告書 -行事食・儀礼食-, 146-147, Feb. 2011.
5.	Kaori Kanemaru : 乾燥発酵オカラの機能性評価, オカラを原料とする飼料の高品質化に関する研究・研究報告書(平成16年度徳島県新産業創出総合支援事業中核4分野研究調査事業・社団法人発明協会徳島県支部), 7-11, 2005.
6.	有内尚子, 遠藤千鶴, 大福月江, Kaori Kanemaru, 高橋啓子, 田村咲江, 松下純子 and 山田和子 : 「調理文化の地域性と調理科学 -魚介類-」報告書(徳島県), 平成15・16年度日本調理科学特別研究「調理文化の地域性と調理科学」報告書 -魚介類の調理-, 197-203, 2004.
7.	Kaori Kanemaru : 徳島の「いも類・豆類」の料理, 日本調理科学会中国・四国支部創立30周年記念誌, 46-49, 2003.
8.	Kaori Kanemaru : ガン細胞増殖抑制活性を有する海草成分の検索, 浦上財団研究報告書(平成12年度財団法人浦上・食文化振興財団研究助成), Vol.10, 44-53, 2002.
9.	Kaori Kanemaru, 田村咲江 and 宇山裕子 : 「豆・いも類利用の地域特性」報告書(徳島県), 平成13・14年度日本調理科学特別研究「調理文化の地域性と調理科学」報告書 -豆・いも類利用の地域性-, 215-217, 2002.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

Adsorption and removal of O157 Shiga toxin by indigestible food ingredients (Project/Area Number: 21K02092 )
難消化性食品成分の志賀毒素の吸着性 (Project/Area Number: 18K02204 )
Analysis on various toxic actions of organotins including tri-n-butyltin (Project/Area Number: 12680544 )
Search by Researcher Number (00243676)

Professor, Associate Professor, Associate Professor : Kanemaru, Kaori

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Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)