label: url

en: Synthesis of a novel 1,2-dithianenucleoside via Pummerer-like reaction, followed by Vorbruggen glycosylation between a 1,2-dithiane derivative and uracil

en: The novel 1,2-dithianenucleoside was designed as a hybrid type of modification between 4'-thioribonucleoside and altritol nucleoside. The desired compound, i.e., 1-[(3R,4R,5S,6R)-4,5-dihydroxy-6-hydroxymethyl-1,2-dithianyl]uracil (20), was prepared via the Pummerer-like reaction, followed by Vorbruggen glycosylation between an appropriately protected 1,2-dithiane derivative and silylated uracil.

en: Chemical Communications

ja: Chemical Communications


en: Leishmanicidal activities and cytotoxicities of bisnaphthoquinone analogues and naphthol derivatives from Burman Diospyros burmanica

en: A methanol extract of the wood of Diospyros burmanica, collected in Burma (Myanmar), was found to exhibit significant activity against Leishmania major. Subsequent chromatographically resolved fractionation led to the isolation of three novel bisnaphthoquinone analogues, burmanin A, B, and C (1-3), together with nine known compounds (4-12). The structure of 1 was confirmed by X-ray crystallography, and those of 2 and 3 by spectroscopic techniques, including 1D and 2D NMR. The inhibitory activities of the isolates were evaluated against the promastigote forms of Leishmania major and the murine macrophage-like cell line, RAW264.7.

en: Bioorganic & Medicinal Chemistry

ja: Bioorganic & Medicinal Chemistry


en: Thermal cyclotrimerization of tetraphenyl[5]cumulene (tetraphenylhexapentaene) to a tricyclodecadiene derivative

en: Tetraphenyl[5]cumulene (tetraphenylhexapentaene) underwent cyclotrimerization in refluxing toluene for 10-15 min to give a tricyclodecadiene derivative in 68% yield.


en: Isolation and Absolute Configuration Determination of Aliphatic Sulfates as the Daphnia Kairomones Inducing Morphological Defense of a Phytoplankton

en: 2,6-Dimethylheptyl sulfate (1) and 6-methyloctyl sulfate (3) were isolated from Daphnia pulex as the Daphnia kairomones that induced morphological defense of a freshwater phytoplankton Scenedesmus gutwinskii var. heterospina (NIES-802). The absolute stereochemistry at C2 of 1 was determined by (1)H-NMR analysis of the (R)-MTPA ester of alcohol 2. The absolute configuration at C6 of 3 was determined by Ohrui's method applied to alcohol 4.

en: Chemical & Pharmaceutical Bulletin

ja: Chemical & Pharmaceutical Bulletin


en: Aliphatic sulfates released from Daphnia induce morphological defense of phytoplankton: isolation and synthesis of kairomones

en: Tetrahedron Letters

ja: Tetrahedron Letters


en: New Ring-Expansion Reactions of Hydroxy Propenoyl Cyclic Compounds under Palladium(0)/Phosphine-Catalyzed Conditions

en: [reaction: see text] Palladium(0)-catalyzed one-atom ring-expansion of 1-hydroxy-2,2-dialkyl-1-propenoylindan derivatives has been achieved in the presence of P(o-tolyl)(3) giving 2-hydroxy-3,3-dialkyl-2-vinyl-1-tetralone derivatives in excellent yields. This ring-expansion reaction was applied to a 17-(1-oxo-2-propenyl)-beta-estradiol derivative and furnished a similar ring-expanded product in an excellent yield.

en: Organic Letters

ja: Organic Letters


en: 1,3-Dipolar addition of nitrones to symmetrically substituted allenes: for the determination of absolute configuration of chiral allenes by NMR spectroscopy


en: Fucoxanthin and Its Metavolites in Edible Brown Algae Cultivated in Deep Seawater.

en: Marine Drugs

ja: Marine Drugs


en: Fucoxanthin and Its Metabolites in Edible Brown Algae Cultivated in Deep Seawater


ja: Fucoxanthin and Its Metabolites in Edible Brown Algae Cultivated in Deep Seawater


en: Oxidation of Cyclopropane Terpenoids with Ruthenium Tetraoxide

en: Oxidation products of cyclopropanoid terpenes, (-)-carane (4), (+)-cyclosativene (5), laurinterol methyl ether (6), and thujopsane (7), with ruthenium tetraoxide were investigated.


en: A New Convenient Method for Synthesis of 3-(2-Oxoethylidene)isoindolin-1-ones Employing Palladium(II) Acetate and DDQ

en: Heterocycles

ja: Heterocycles


en: Structures of the radical (DPPH) oxidation products of dihydrocapsaicin


en: A New Diterpene Dimer from the Bark of Chamaecyparis obtusa

en: Journal of Wood Science

ja: Journal of Wood Science


en: Carbon-13 Spin-Lattice Relaxation Time (T1) for Assignment of Brominated Carbons


en: NMR Study of Acutanol, a New Cembrene Alcohol, and Sarcophytol A Isolated from the Soft coral Sarcophyton acutangulum

en: Spectroscopy: An International Journal

ja: Spectroscopy: An International Journal


en: New Terpenoid Components from the Volatile Oils of the Soft Corals Clavularia viridis and Sarcophyton acutangulum

en: A new tetracyclic terpenoid hydrocarbon, cyclosinularane (1), and (+)-alloaromadendrene (2), the enantiomer of terrestrial (-)-alloaromadendrene, have been isolated from the volatile oil of the soft corals Clavularia viridis and Sarcophyton acutangulum, respectively. Their structures have been determined on the basis of NMR spectral analysis and their chiroptical properties.

en: Journal of Natural Products

ja: Journal of Natural Products


en: Influence of the Conformation of Methoxy-(2-naphthyl)acetates (2NMA Esters) on Their Chemical Reactions

en: An SN2 reaction (NaI) of 1,7-di(methanesulfoxyl)heptadien-4-yl methoxy-(2-naphthyl)acetate and a tributyltin hydride reduction of 1,7-diiodo-4-yl methoxy-(2-naphthyl)acetate (2NMA) is crucial for determination of the absolute configuration of secondary alcohols.

en: Chemical & Pharmaceutical Bulletin


en: Sesterterpenoids and Diterpenoids of the Wax Excreted by a Scale Insect, Ceroplastes pseudoceriferus

en: A new sesterterpene, (2Z,6Z,10E)-cericerene-15,24-diol (1), and its 30-hydroxytriacontanoate (2) were isolated from the wax exuded by the scale insect Ceroplastes pseudoceriferus, together with the acetates and 30-hydroxytriacontanoates of 3,15-dihydroxy- and 15, 20-dihydroxylabda-7,13-diene (3-6). The absolute configurations of the labdadiene alcohols were antipodal to the ordinary labdanes isolated from terrestrial plants.


en: Application of the modified Mosher's method to linear 1,3-diols

en: Tetrahedron Letters


en: Structure and Absolute Stereochemistry of Five New Secospatanes and a Spatane Isolated from the Brown Alga Dilophus okamurai Dawson


en: Determination of the absolute configuration of linear secondary alcohols adopting one enantiomer of the chiral anisotropic reagents, methoxy-(1-and 2-naphthyl)acetic acids


en: Crenulacetal C, a Marine Diterpene, and Its Synthetic Mimics Inhibiting Polydora websterii, a Harmful Lugworm Damaging Peral Cultivation


en: A simple preparation of 17(R)-hydroxyeicosatetraenoic and eicosapentaenoic acids from the eicosanoylphloroglucinols, components of the brown alga, Zonaria diesingiana


en: Application of phenylglycine methyl ester (PGME) to determination of the absolute configuration of carboxylic acids having phenylalkyl group

en: Chirality

ja: Chirality


en: Absolute Configurations of Some Hydroxy-fatty Acids Produced by the Insect Genus Laccifer

en: Bioscience, Biotechnology, and Biochemistry


en: Absolute stereostructure of a 2,3,7,13-tetrahydroxyoctadecanoic acid, the framework of taurolipid B produced by a fresh-water protozoan, Tetrahymena thermophila


en: Crystal Structure of 2-[1-(2,4-Dinitrophenyl)ethyl]-1,10-Phenanthroline

en: The crystal structure of 2-[1-(2,4-dinitrophenyl)ethyl]-1,10-phenanthroline was determined by X-ray crystallography. The compound crystallizes in a monoclinic system and was characterized thus: P21/n, a = 15.477(2), b = 5.1818(6), c = 21.754(2)Å, β = 96.295(3)°, Z = 4, V = 1734.12 Å3. The crystal structure was solved by direct methods and refined by full-matrix least-squares on F2 to final values of R = 0.0600.

en: X-ray Structure Analysis Online

ja: X-ray Structure Analysis Online