label: url

en: 血液透析診療指針 --- 皮膚疾患診療指針

ja: 血液透析診療指針 --- 皮膚疾患診療指針

en: TOKYO IGAKUSHA

ja: 株式会社 東京医学社


en: Verrucous carcinoma of the scalp associated with human papillomavirus type 33

en: Blackwell Publishing Ltd

ja: Blackwell Publishing Ltd

en: Verrucous carcinoma (VC) is a low-grade, well-differentiated squamous cell carcinoma of the skin or mucosae, and human papillomavirus (HPV) infection has been considered to be one of the causative factors of VC at three main sites, including the oral cavity, the genitoanal region, and the foot. However, the relationship between cutaneous VC at other sites and HPV infection remains obscure. We describe a rare case of cutaneous VC originating in a burn scar on the scalp and our attempt to find HPV infection in the lesion. We investigated the presence of HPV by polymerase chain reaction-restriction fragment length polymorphisms and immunohistochemical analysis. HPV type 33 was detected in the lesion, and positive stains for HPV were observed in several cell nuclei at the upper stratum malpighi. Since HPV type 33, as well as HPV types 16 and 18, is regarded as a high-risk, mucosal type, HPV type 33 infection likely contributed to the development of the lesion. We suggest that HPV infection should be relevant to a subset of cutaneous VC.


en: Three cases of Bowen's disease on the lower abdomen associated with high-risk types 16, 33, and 59 of human papillomavirus

en: Elsevier Science

ja: Elsevier Science


en: Bowen's disease on the sole: p16INK4a overexpression associated with human papillomavirus type 16

en: We report a case of Bowen's disease on the sole presenting clinically as an exophytic, blackish-grey, verrucous tumour, and showing human papillomavirus (HPV) type 16 on analysis with polymerase chain reaction. Positive stains for HPV particles by immunohistochemical analysis were limited to several cell nuclei at the upper stratum Malpighii. However, all the tumour cells in the epidermis exhibited strong and diffuse nuclear and cytoplasmic stains for the tumour suppressor protein p16INK4a. We speculate that dysregulation of the retinoblastoma/p16INK4a pathway may be involved in the pathogenesis of the lesion, and p16INK4a overexpression might serve as a useful surrogate marker for identifying Bowen's disease harbouring high-risk types of HPV infection.


en: Tailgut Cyst as a Subcutaneous Tumor at the Coccygeal Region

en: Lippincott Williams & Wilkins

ja: Lippincott Williams & Wilkins


en: 神経症性擦傷

ja: 神経症性擦傷

en: KANEHARA & CO., LTD.

ja: 金原出版 株式会社


en: 肛囲に生じた基底細胞癌の1例

ja: 肛囲に生じた基底細胞癌の1例

en: IGAKU-SHOIN Ltd.Tokyo,Japan

ja: 株式会社 医学書院


en: 小児に生じた隆起性皮膚線維肉腫の1例

ja: 小児に生じた隆起性皮膚線維肉腫の1例


en: Tufted Hair Folliculitiesの1例

ja: Tufted Hair Folliculitiesの1例


en: 頭皮欠損症を合併した13トリソミー症候群の1例

ja: 頭皮欠損症を合併した13トリソミー症候群の1例