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en: Introduction of proteomic approach to environmental medicine

ja: 環境医学領域におけるプロテオミクスの導入

en: Japanese Journal of Hygiene

ja: 日本衛生学雑誌


en: Risk assessment of environmental factors and contribution to disease prevention

ja: 環境要因の健康リスク評価と疾病予防への貢献

en: The research interest of authors has focused on the risk assessment of environmental pollutantssuch as cadmium and dioxin-related compounds, and epidemiology of human T-cell lymphotropicvirus type-I(HTLV-I)infection. The authors(1)showed that low-molecular weight proteinuriaand reduced glomerular filtration rate caused by environmental cadmium were strongly associatedwith shortened survival，(2)clarified serological risk factors for development of adult T-cellleukemia/lymphoma among asymptomatic HTLV-I carriers(plasma levels of soluble interleukin2-receptor>＝500U/ml and HTLV-I antibody titer>＝1，024)，(3)conducted the first prospectivestudy of HTLV-I infection and development of malignances other than ATL, and found a significantlyreduced risk of gastric cancer among HTLV-I carriers, and(4)by a cooperative study, clarified anew pathogenicity of HTLV-I(association with Sj¨ogren's syndrome)

en: Shikoku Acta Medica

ja: 四国医学雑誌