! Kayoko Uezu, Hiroyoshi Sei, Atsuko Sano, Kazunori Toida, Toshiko Suzuki-Yamamoto, Takeshi Houtani, Tetsuo Sugimoto, Hiroshi Takeshima, Kazunori Ishimura and Yusuke Morita : Lack of nociceptin receptor alters body temperature during resting period in mice, NeuroReport, Vol.15, No.5, 751-755, 2004. Kazuyoshi Kitaoka, Risa Ito, Hideo Araki, Hiroyoshi Sei and Yusuke Morita : Effect of mood state on anticipatory postural adjustments., Neuroscience Letters, Vol.370, No.1, 65-68, 2004. 勢井 宏義 : 睡眠と生体リズム, 四国医学雑誌, Vol.60, No.1-2, 8-13, 2004年5月. Kayoko Uezu, Atsuko Sano, Hiroyoshi Sei, Kazunori Toida, Takeshi Houtani, Tetsuo Sugimoto, Toshiko Suzuki-Yamamoto, Hiroshi Takeshima, Kazunori Ishimura and Yusuke Morita : Enhanced hippocampal acetylcholine release in nociceptin-receptor knockout mice, Brain Research, Vol.1050, No.1-2, 118-123, 2005. K Kitahama, S Araneda, M Geffard, Hiroyoshi Sei and H Okamura : Tyramine-immunoreactive neuronal structures in the rat brain: Abundance in the median eminence of the mediobasal hypothalamus, Neuroscience Letters, Vol.383, No.3, 215-219, 2005. Hirofumi Hashimoto, Tatsushi Onaka, Makoto Kawasaki, Lei Chen, Takashi Mera, Atsushi Soya, Takeshi Saito, Hiroaki Fujihara, Hiroyoshi Sei, Yusuke Morita and Yoichi Ueta : Effects of cholecystokinin (CCK)-8 on hypothalamic oxytocin-secreting neurons in rats lacking CCK-A receptor, Autonomic Neuroscience : Basic & Clinical, Vol.121, No.1-2, 16-25, 2005. Mie Sakata, Hiroyoshi Sei, Naomi Eguchi, Yusuke Morita and Yoshihiro Urade : Arterial Pressure and Heart Rate Increase during REM Sleep in Adenosine A2A-Receptor Knockout Mice, but not in Wild-Type Mice, Neuropsychopharmacology, Vol.30, No.10, 1856-1860, 2005. 森島 真幸, 原 小百合, 原田 永勝, 佐野 敦子, 妹尾 廣正, 髙橋 章, 中屋 豊 : 高運動モデルラットSPORTSの海馬におけるノルエピネフリン動態と自発運動量, 四国医学雑誌, Vol.61, No.5,6, 185-188, 2005年. M Morishima, Nagakatsu Harada, S Hara, Atsuko Sano, Hiromasa Seno, Akira Takahashi, Yusuke Morita and Yutaka Nakaya : Monoamine Oxidase A Activity and Norepinephrine Level in Hippocampus Determine Hyperwheel Running in SPORTS Rats., Neuropsychopharmacology, Vol.31, No.12, 2627-2638, 2006. Ryou Urushihara, Nagako Murase, C John Rothwell, Masafumi Harada, Yuki Hosono, Kotaro Asanuma, Hideki Shimazu, Kazumi Nakamura, Sachiko Chikahisa, Kazuyoshi Kitaoka, Hiroyoshi Sei, Yusuke Morita and Ryuji Kaji : Effect of repetitive transcranial magnetic stimulation applied over the premotor cortex on somatosensory-evoked potentials and regional cerebral blood flow., Neuroimage, Vol.31, No.2, 699-709, 2006. Tadashi Wada, Hiroyoshi Sei, Kenji Kusumoto, Kazuyoshi Kitaoka, Sachiko Chikahisa, Kazuhito Rokutan and Yusuke Morita : Geranylgeranylacetone, an inducer of HSP 70, attenuates REM sleep rebound after sleep deprivation., Brain Research Bulletin, Vol.69, No.4, 388-392, 2006. 勢井 宏義 : 睡眠と生体リズムの最新の知見, 四国医学雑誌, Vol.61, No.1-2, 2-6, 2005年4月. 森島 真幸, 原田 永勝, 原 小由合, 佐野 敦子, 妹尾 廣正, 髙橋 章, 中屋 豊 : 高運動性モデルラットSPORTSにおける運動習性と脳内モノアミン制御., 第59回日本栄養食糧学会, 2005年5月. 森島 真幸, 原 小由合, 原田 永勝, 佐野 敦子, 妹尾 廣正, 髙橋 章, 中屋 豊 : 高運動性モデルラットSPORTSにおける海馬ノルエピネフリン動態は運動習性を調節する., 第82回日本生理学会, 2005年5月. 水主 智佳, 樋田 一徳, 宝谷 剛志, 清蔭 恵美, 勢井 宏義, 山本 登志子, 杉本 哲夫, 石村 和敬 : ノシセプチン受容体の脳内局在ー視床下部·中隔·海馬ー, 日本顕微鏡学会第50回シンポジウム, PB-2, 2005年11月. Sachiko Chikahisa, Hiroyoshi Sei, Masaki Morishima, Atsuko Sano, Kazuyoshi Kitaoka, Yutaka Nakaya and Yusuke Morita : Exposure to music in the perinatal period enhances learning performance and alters BDNF/TrkB signaling in mice as adults., Behavioural Brain Research, Vol.169, No.2, 312-319, 2006. Sachiko Chikahisa, Atsuko Sano, Kazuyoshi Kitaoka, Ken-ichi Miyamoto and Hiroyoshi Sei : Anxiolytic effect of music depends on ovarian steroid in female mice., Behavioural Brain Research, Vol.179, No.1, 50-59, 2007. Kazuyoshi Kitaoka, Atsushi Hattori, Sachiko Chikahisa, Ken-ichi Miyamoto, Yutaka Nakaya and Hiroyoshi Sei : Vitamin A deficiency induces a decrease in EEG delta power during sleep in mice, Brain Research, Vol.1150, 121-130, 2007. Sachiko Chikahisa, Hiroyoshi Sei, Atsuko Sano, Kazuyoshi Kitaoka and Yusuke Morita : Anxiolytic effects of music depend on ovarian steroid in female mice, International Behavioral Neuroscience Society, Whistler, Canada, May 2006. Sachiko Chikahisa, Hiroyoshi Sei, Masaki Morishima, Atsuko Sano, Kazuyoshi Kitaoka, Yutaka Nakaya and Yusuke Morita : Exposure to music in the perinatal period enhances learning performance and alters BDNF/TrkB signaling in mice as adults, Neuroscience 2006, Atlanta, USA, Oct. 2006. Miyazaki Koyomi, Wakabayashi Miyuki, Sachiko Chikahisa, Hiroyoshi Sei and Norio Ishida : PER2 controls circadian periods through nuclear localization in the suprachiasmatic nucleus, Genes to Cells, Vol.12, No.11, 1225-1234, 2007. Masamichi Kuwajima, Hiroaki Fujihara, Hiroyoshi Sei, Asako Umehara, Masako Sei, Tomi T. Tsuda, Akiko Sukeno, Tatsuya Okamoto, Akiko Inubushi, Yoichi Ueta, Toshio Doi and Hiroshi Kido : Reduced carnitine level causes death from hypoglycemia: possible involvement of suppression of hypothalamic orexin expression during weaning period., Endocrine Journal, Vol.54, No.6, 911-925, 2007. Katsutaka Oishi, Naoki Ohkura, Hiroyoshi Sei, Juzo Matsuda and Norio Ishida : CLOCK regulates the circadian rhythm of kaolin-induced writhing behavior in mice., NeuroReport, Vol.18, No.18, 1925-1928, 2007. Hiroyoshi Sei : Vitamin A and sleep regulation, The Journal of Medical Investigation : JMI, Vol.55, No.1-2, 1-8, Feb. 2008. Sachiko Chikahisa, Kazuyoshi Kitaoka, Hiroyoshi Sei, Katsutaka Oishi, Shigenobu Shibata and Norio Ishida : Chronic bezafibrate treatment advances circadian rhythms of sleep and body temperature in mice, 2nd World Congress of Chronobiology, Tokyo, Nov. 2007. Hiroyoshi Sei, Sachiko Chikahisa, Kazuyoshi Kitaoka and Tomoko Kawai : Relationship between spontaneous apnea and surge of arterial pressure during REM sleep in ICR mice, Neuroscience 2007, San Diego, USA, Nov. 2007. Hiroyoshi Sei, Katsutaka Oishi, Sachiko Chikahisa, Kazuyoshi Kitaoka, Eiji Takeda and Norio Ishida : Diurnal amplitudes of arterial pressure and heart rate are dampened in Clock mutant mice and adrenalectomized mice., Endocrinology, Vol.149, No.7, 3576-3580, 2008. Sachiko Chikahisa, Kumiko Tominaga, Tomoko Kawai, Kazuyoshi Kitaoka, Katsutaka Oishi, Norio Ishida, Kazuhito Rokutan and Hiroyoshi Sei : Bezafibrate, a PPARs agonist, decreases body temperature and enhances EEG delta oscillation during sleep in mice., Endocrinology, Vol.149, No.10, 5262-5271, 2008. Kazuyoshi Kitaoka, Kaoru Uchida, Naoko Okamoto, Sachiko Chikahisa, Toshitsugu Miyazaki, Eiji Takeda and Hiroyoshi Sei : Fermented ginseng improves the first-night effect in humans, Sleep, Vol.32, No.3, 413-421, 2009. Tokiko Ogawa, Nobue Shishioh-Ikejima, Hiroyuki Konishi, Tetsuya Makino, Hiroyoshi Sei, Sumiko Kiryu-Seo, Masaaki Tanaka, Yasuyoshi Watanabe and Hiroshi Kiyama : Chronic stress elicits prolonged activation of alpha-MSH secretion and subsequent degeneration of melanotroph., Journal of Neurochemistry, Vol.109, No.5, 1389-1399, 2009. 近久 幸子, 勢井 宏義 : 睡眠とエネルギー代謝∼核内受容体との関係から∼, 健康開発, Vol.12, No.3, 28-33, 2008年5月. Sachiko Chikahisa, Kazuyoshi Kitaoka and Hiroyoshi Sei : Complex auditory stimuli reduce anxiety level in an ovarian steroid hormone-dependent manner in female mice, Neuroscience 2008, Washington DC, USA, Nov. 2008. Hiroyoshi Sei, Sachiko Chikahisa, Kumiko Tominaga, Tomoko Kawai, Katsutaka Oishi, Norio Ishida and Kazuhito Rokutan : Bezafibrate, a PPARs agonist, enhances EEG delta oscillation during NREM sleep in mice, Neuroscience 2008, Washington DC, USA, Nov. 2008. Sachiko Chikahisa, Nobuhiro Fujiki, Kazuyoshi Kitaoka, Noriyuki Shimizu and Hiroyoshi Sei : Central AMPK contributes to sleep homeostasis in mice, Neuropharmacology, Vol.57, No.4, 369-374, 2009. Yuta Yamamoto, Toshihito Tanahashi, Tomoko Kawai, Sachiko Chikahisa, Sakurako Katsuura, Kensei Nishida, Shigetada Teshima-Kondo, Hiroyoshi Sei and Kazuhito Rokutan : Changes in behavior and gene expression induced by caloric restriction in C57BL/6 mice., Physiological Genomics, Vol.39, No.3, 227-235, 2009. Yuta Yamamoto, Toshihito Tanahashi, Tomoko Kawai, Sachiko Chikahisa, Sakurako Katsuura, Kensei Nishida, Shigetada Teshima-Kondo, Hiroyoshi Sei and Kazuhito Rokutan : Changes in behavior and gene expression induced by caloric restriction in C57BL/6 mice., Physiological Genomics, Vol.39, No.3, 227-235, 2009. Katsutaka Oishi, Katsuhiko Sakamoto, Morichika Konishi, Yusuke Murata, Nobuyuki Itoh and Hiroyoshi Sei : FGF21 is dispensable for hypothermia induced by fasting in mice., Neuroendocrinology Letters, Vol.31, No.2, 198-202, 2010. Kazuyoshi Kitaoka, Atsuko Sano, Sachiko Chikahisa, Kazuo Yoshizaki and Hiroyoshi Sei : Disturbance of rapid eye movement sleep in senescence-accelerated mouse prone/8 mice is improved by retinoic acid receptor agonist Am80 (Tamibarotene)., Neuroscience, Vol.167, No.3, 573-582, 2010. Shinya Ozaki, Kazunori Toida, Motohiko Suzuki, Yoshihisa Nakamura, Nobuaki Ohno, Taku Ohashi, Meiho Nakayama, Yuki Hamajima, Akira Inagaki, Kazuyoshi Kitaoka, Hiroyoshi Sei and Shingo Murakami : Impaired olfactory function in mice with allergic rhinitis., Auris, Nasus, Larynx, Vol.37, No.5, 575-583, 2010. Kazuyoshi Kitaoka, Atsuko Sano, Sachiko Chikahisa, Kazuo Yoshizaki and Hiroyoshi Sei : Administration of Am80, an agonist of retinoic acid receptor, improves the aging-related decrease of REM sleep in SAMP8 mice, 36th International Congress of Physiological Sciences, Aug. 2009. Sachiko Chikahisa, Noriyuki Shimizu, Kazuyoshi Kitaoka, Nobuhiro Fujiki and Hiroyoshi Sei : Central AMPK contributes to sleep regulation, 36th International Union of Physiological Sciences, Kyoto, Aug. 2009. Noriyuki Shimizu, Masahiro Oura, Sachiko Chikahisa and Hiroyoshi Sei : EEG delta power in NREM sleep is enhanced by refeeding after 24-hr fasting in time-dependent manner, 36th International Union of Physiological Sciences, Kyoto, Aug. 2009. Noriyuki Shimizu, Masahiro Oura, Sachiko Chikahisa and Hiroyoshi Sei : EEG delta power in NREM sleep is enhanced by refeeding after 24-hr fasting in time-dependent manner, 36th International Union of Physiological Sciences, Kyoto, Aug. 2009. Kazuyoshi Kitaoka, Shimizu Mika, Sachiko Chikahisa, Kazuo Yoshizaki and Hiroyoshi Sei : Four-week administration of retinoic acid receptors antagonist LE540 attenuates EEG delta power during sleep in mice, The 6Th Congress of Asian Sleep Research Society, Oct. 2009. Hiroyoshi Sei, Sachiko Chikahisa and Noriyuki Shimizu : Role of central AMPK in sleep homeostasis, The 6th Congress of Asian Sleep Research SocietyThe 34th Annual Meeting of Japanese Society of Sleep Research, Osaka, Oct. 2009. Noriyuki Shimizu, Sachiko Chikahisa, Masahiro Oura and Hiroyoshi Sei : Refeeding at light-onset after 24h fasting enhances EEG delta-power in NREM sleep in mice, The 6th Congress of Asian Sleep Research SocietyThe 34th Annual Meeting of Japanese Society of Sleep Research, Osaka, Oct. 2009. 勢井 宏義 : 血圧の概日リズムをつくる時計遺伝子, 2010年11月. 勢井 宏義 : 脳の電気的活動,睡眠ー覚醒状態,サーカディアンリズム, 丸善株式会社, 2011年1月. 勢井 宏義 : 血圧・心拍の概日リズムをつくる時計分子, 日本心臓財団, 2011年2月. E Matthew Carter, Ofer Yizhar, Sachiko Chikahisa, Hieu Nguyen, Antoine Adamantidis, Seiji Nishino, Karl Deisseroth and Luis Lecea de : Tuning arousal with optogenetic modulation of locus coeruleus neurons., Nature Neuroscience, Vol.13, No.12, 1526-1533, 2010. Noriaki Sakai, Sachiko Chikahisa and Seiji Nishino : Stimulants in excessive daytime sleepiness, Sleep Medicine Clinics, Vol.5, No.4, 591-607, 2010. Yuta Yamamoto, Toshihito Tanahashi, Sakurako Katsuura, Ken Kurokawa, Kensei Nishida, Yuki Kuwano, Tomoko Kawai, Shigetada Teshima-Kondo, Sachiko Chikahisa, Yoshihiro Tsuruo, Hiroyoshi Sei and Kazuhito Rokutan : Interleukin-18 deficiency reduces neuropeptide gene expressions in the mouse amygdala related with behavioral change., Journal of Neuroimmunology, Vol.229, No.1-2, 129-139, 2010. Yoichi Ueta, Govindin Dayanithi and Hiroaki Fujihara : Hypothalamic vasopressin response to stress and various physiological stimuli: visualization in transgenic animal models., Hormones and Behavior, Vol.59, No.2, 221-226, 2010. Kunitoshi Uchida, Katsuya Dezaki, Boldbaatar Damdindorj, Hitoshi Inada, Tetsuya Shiuchi, Yasuo Mori, Toshihiko Yada, Yasuhiko Minokoshi and Makoto Tominaga : Lack of TRPM2 Impaired Insulin Secretion and Glucose Metabolisms in Mice., Diabetes, Vol.60, No.1, 119-126, 2011. Kumiko Saito, Suni Lee, Tetsuya Shiuchi, Chitoku Toda, Masahiro Kamijo, Kyoko Inagaki-Ohara, Shiki Okamoto and Yasuhiko Minokoshi : An enzymatic photometric assay for 2-deoxyglucose uptake in insulin-responsive tissues and 3T3-L1 adipocytes., Analytical Biochemistry: Methods in the Biological Sciences, Vol.412, No.1, 9-17, 2011. Toru Yokoyama, Toyoaki Ohbuchi, Takeshi Saito, Yuka Sudo, Hiroaki Fujihara, Kouichiro Minami, Toshihisa Nagatomo, Yasuhito Uezono and Yoichi Ueta : Allyl isothiocyanates and cinnamaldehyde potentiate miniature excitatory postsynaptic inputs in the supraoptic nucleus in rats., European Journal of Pharmacology, Vol.655, No.1-3, 31-37, 2011. Eiko Matsuo, Ayako Mochizuki, Kiyomi Nakayama, Shiro Nakamura, Takashi Yamamoto, Seiji Shioda, Takeshi Sakurai, Masashi Yanagisawa, Tetsuya Shiuchi, Yasuhiko Minokoshi and Tomio Inoue : Decreased intake of sucrose solutions in orexin knockout mice., Journal of Molecular Neuroscience : MN, Vol.43, No.2, 217-224, 2011. 志内 哲也, 箕越 靖彦 : 視床下部を介したエネルギー代謝調節機構, Annual Review 糖尿病・代謝・内分泌 2011, Vol.2011, 4-11, 2011年. Kazuyoshi Kitaoka, Shimizu Mika, Shimizu Noriyuki, Sachiko Chikahisa, Kazuo Yoshizaki and Hiroyoshi Sei : Retinoic acid receptors antagonist LE540 atenuates EEG delta power during sleep via dopamine D1 receptor in mice, Neuroscience 2010, San Diego, Nov. 2010. Sachiko Chikahisa, Kazuyoshi Kitaoka, Noriyuki Shimizu and Hiroyoshi Sei : Hypothalamic AMPK contributes to homeostatic sleep regulation, Neuroscience 2010, San Diego, USA, Nov. 2010. Noriyuki Shimizu, Sachiko Chikahisa, Kazuyoshi Kitaoka and Hiroyoshi Sei : Sleep regulation in PPARalpha knockout mice, Neuroscience 2010, San Diego, USA, Nov. 2010. 近久 幸子, 勢井 宏義 : 中枢脂質代謝と睡眠ホメオスタシス, 日本睡眠学会第35回定期学術集会, 2010年7月. 原田 慎吾, 小川 眞太郎, 四柳 浩之, 勢井 宏義, 橋爪 正樹 : An LED Lighting Control Circuit to Measure Light Wavelength Dependence on Circadian Rhythm in Mice, 電気関係学会四国支部連合大会講演論文集, 80, 2010年9月. 北岡 和義, 大西 健, 清水 紀之, 近久 幸子, 小川 眞太朗, 吉﨑 和男, 勢井 宏義 : HSF1はマウスの睡眠調節に関与する, 第5回臨床ストレス応答学会大会, 2010年11月. 戸田 聡美, 阪上 浩, 谷口 康子, 原田 永勝, 馬渡 一諭, 中屋 豊, 志内 哲也, 箕越 靖彦 : 自発運動制御におけるGhrelinの役割, 第14回日本病態栄養学会,神奈川県横浜市, 2011年1月. Yasuhiko Minokoshi and Tetsuya Shiuchi : Regulatory mechanism of hypothalamic orexin in energy metabolism in skeletal muscle, 日本生理学会, Mar. 2011. 堀尾 修平, 北池 秀次, 志内 哲也, 箕越 靖彦, 三宝 誠, 平林 敬浩, 八木 健, 甲斐 信行, 上山 敬司, 福井 裕行 : 視床下部ヒスタミンH1受容体発現ニューロンの選択的破壊を利用した摂食調節機構の研究, 第88回日本生理学会大会 第116回日本解剖学会総会・全国学術集会合同大会, 2011年3月. Toyoaki Ohbuchi, Toru Yokoyama, Takeshi Saito, Jun-Ichi Ohkubo, Hitoshi Suzuki, Toru Ishikura, Akiko Katoh, Hiroaki Fujihara, Hirofumi Hashimoto, Hideaki Suzuki and Yoichi Ueta : Possible contribution of pannexin channel to ATP-induced currents in vitro in vasopressin neurons isolated from the rat supraoptic nucleus., Brain Research, Vol.1394, 71-78, 2011. Rie Yamamoto, Hiroshi Akazawa, Hiroaki Fujihara, Yukako Ozasa, Noritaka Yasuda, Kaoru Ito, Yoko Kudo, Yingjie Qin, Yoichi Ueta and Issei Komuro : Angiotensin II type 1 receptor signaling regulates feeding behavior through anorexigenic corticotropin-releasing hormone in hypothalamus., The Journal of Biological Chemistry, Vol.286, No.24, 21458-21465, 2011. Hitoshi Suzuki, Hirofumi Hashimoto, Makoto Kawasaki, Miho Watanabe, Hiroki Otsubo, Toru Ishikura, Hiroaki Fujihara, Hideo Ohnishi, Etsuro Onuma, Hisafumi Yamada-Okabe, Yoh Takuwa, Etsuro Ogata, Toshitaka Nakamura and Yoichi Ueta : Similar changes of hypothalamic feeding-regulating peptides mRNAs and plasma leptin levels in PTHrP-, LIF-secreting tumors-induced cachectic rats and adjuvant arthritic rats., International Journal of Cancer, Vol.128, No.9, 2215-2223, 2011. Akiko Katoh, Hiroaki Fujihara, Toyoaki Ohbuchi, Tatsushi Onaka, Takashi Hashimoto, Mitsuhiro Kawata, Hideaki Suzuki and Yoichi Ueta : Highly visible expression of an oxytocin-monomeric red fluorescent protein 1 fusion gene in the hypothalamus and posterior pituitary of transgenic rats., Endocrinology, Vol.152, No.7, 2768-2774, 2011. Noriyuki Shimizu, Sachiko Chikahisa, Kazuyoshi Kitaoka, Seiji Nishino and Hiroyoshi Sei : Refeeding after a 24-hour fasting deepens NREM sleep in a time-dependent manner., Physiology & Behavior, Vol.104, No.3, 480-487, 2011. Masaru Iwanaga, Motoko Ohno, Akiko Katoh, Toyoaki Ohbuchi, Toru Ishikura, Hiroaki Fujihara, Masayoshi Nomura, Kenji Hachisuka and Yoichi Ueta : Upregulation of arginine vasopressin synthesis in the rat hypothalamus after kainic acid-induced seizures., Brain Research, Vol.1424, 1-8, 2011. Kazuyoshi Kitaoka, Mika Shimizu, Noriyuki Shimizu, Sachiko Chikahisa, Madoka Nakagomi, Koichi Shudo, Kazuo Yoshizaki and Hiroyoshi Sei : Retinoic acid receptor antagonist LE540 attenuates wakefulness via the dopamine D1 receptor in mice, Brain Research, Vol.1423, 10-16, 2011. P Sergiu Paşca, Thomas Portmann, Irina Voineagu, Masayuki Yazawa, Aleksandr Shcheglovitov, M Anca Paşca, Branden Cord, D Theo Palmer, Sachiko Chikahisa, Seiji Nishino, A Jonathan Bernstein, Joachim Hallmayer, H Daniel Geschwind and E Ricardo Dolmetsch : Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome., Nature Medicine, Vol.17, No.12, 1657-1662, 2011. Motoko Ohno, Hiroaki Fujihara, Masaru Iwanaga, Miwako Todoroki, Akiko Katoh, Toyoaki Ohbuchi, Toru Ishikura, Akinori Hamamura, Kenji Hachisuka and Yoichi Ueta : Induction of arginine vasopressin-enhanced green fluorescent protein expression in the locus coeruleus following kainic acid-induced seizures in rats., Stress, Vol.15, No.4, 435-442, 2011. Sachiko Chikahisa and Hiroyoshi Sei : The role of ATP in sleep regulation., Frontiers in Neurology, Vol.2, 87, 2011. Hiroaki Fujihara, Kazuki Sasaki, Emi Mishiro-Sato, Toyoaki Ohbuchi, Govindan Dayanithi, Motoo Yamasaki, Yoichi Ueta and Naoto Minamino : Molecular characterization and biological function of neuroendocrine regulatory peptide-3 in the rat., Endocrinology, Vol.153, No.3, 1377-1386, 2012. Yoshio Takei, C Ray Bartolo, Hiroaki Fujihara, Yoichi Ueta and A John Donald : Water deprivation induces appetite and alters metabolic strategy in Notomys alexis: unique mechanisms for water production in the desert., Proceedings. Biological sciences / The Royal Society, Vol.279, No.1738, 2599-2608, 2012. Nobuya Ogawa, Makoto Ito, Hideki Yamaguchi, Tetsuya Shiuchi, Shiki Okamoto, Korekiyo Wakitani, Yasuhiko Minokoshi and Masamitsu Nakazato : Intestinal fatty acid infusion modulates food preference as well as calorie intake via the vagal nerve and midbrain-hypothalamic neural pathways in rats., Metabolism: Clinical and Experimental, 2012. Sachiko Chikahisa : AMPK and PPAR contribute to sleep homeostasis, Sleep 2011: 25th Anniversary Meeting of the APSS, Minneapolis, USA, Jun. 2011. Sachiko Chikahisa, Yohei Sagawa, Yuji Ishimaru, Noriaki Sakai, Masashi Okuro and Seiji Nishino : Brain resident mast cells affect sleep/wake physiology and pharmacology, Sleep 2011: 25th Anniversary Meeting of the APSS, Minneapolis, USA, Jun. 2011. Sachiko Chikahisa and Hiroyoshi Sei : PPARs, AMPK and sleep homeostasis, 36th Japanase Society of Sleep Research-World sleep 2011 (Kyoto, Japan), Oct. 2011. Sachiko Chikahisa, Noriyuki Shimizu, Kazuyoshi Kitaoka, Yohei Iwaki, Hiroaki Fujihara, Tetsuya Shiuchi and Hiroyoshi Sei : Sleep/wake regulation in PPAR knockout mice, World sleep 2011, Oct. 2011. Noriyuki Shimizu, Sachiko Chikahisa, Yohei Iwaki, Kazuyoshi Kitaoka and Hiroyoshi Sei : Low birth weight by undernutrition during pregnancy elicits anxiety and depression in male offspring mice, World sleep 2011, Kyoto, Oct. 2011. Hiroyoshi Sei, Kazuyoshi Kitaoka, Nobuhiro Fujiki, Noriyuki Shimizu, Sachiko Chikahisa, Hiroaki Fujihara, Tetsuya Shiuchi and A Nakai : Mice lacking heat shock factor 1 show evening-type sleep/wake rhythm, World sleep 2011, Kyoto, Oct. 2011. Sachiko Chikahisa, Noriyuki Shimizu, Hiroaki Fujihara, Tetsuya Shiuchi and Hiroyoshi Sei : Sleep homeostatic regulations in PPAR-knockout mice, Frontiers in Behavioral Brain Science-Solving the mystery of sleep-, Tokyo, Mar. 2012. 志内 哲也, 近久 幸子 : 生体リズムが中枢性代謝調節に与える影響と異所性脂肪蓄積の関連, 第2回 新学術領域研究・班会議, 2011年8月. 志内 哲也 : 神経ペプチド・オレキシンによる骨格筋の糖代謝調節とその生理的役割, 第3回 病態生理学会サテライトシンポジウム, 2011年8月. 志内 哲也 : 視床下部を介したエネルギー代謝調節機構, 第19回 日本運動生理学会, 2011年8月. 堀尾 修平, 志内 哲也, 箕越 靖彦, 小林 和人, 上山 敬司 : マウス視床下部室傍核のヒスタミンH1受容体発現ニューロンの選択的死滅による摂食亢進, 第32回 日本肥満学会, 2011年9月. 志内 哲也 : 脳を介した糖・脂肪酸代謝調節の生理学的解析, 糖尿病臨床開発研究センター講演会, 2011年9月. 志内 哲也 : 運動トレーニングが視床下部神経核における代謝関連遺伝子の発現に及ぼす影響, 第4回 脳・神経・内分泌系から運動の意義を考える会, 2011年9月. 七條 香緒莉, 福田 恵理, 橋爪 正樹, 細野 裕希, 勢井 宏義 : 視覚誘発電位測定用LED刺激装置の開発, --- 情動と光波長感受性の関連性解明に向けて ---, 2011年10月. Kazuyoshi Kitaoka, Shimizu Noriyuki, Sachiko Chikahisa, Nakagomi Madoka, Shudo Koichi, Hiroyoshi Sei and Kazuo Yoshizaki : Chronic administration of retinoic acid receptor agonist Am80 induces the ADAM10 expression in the hippocampus of SAMP8 mice, The 89th Annual Meeting of the Physiological Society of Japan, Mar. 2012. Hiroaki Fujihara, Emi Mishiro-Sato, Kazuki Sasaki, Toyoaki Ohbuchi, Motoo Yamasaki, Yoichi Ueta and Naoto Minamino : Anatomical distributions in the hypothalamus and biological function of neuroendocrine regulatory peptide-3 in the rats, 第89回日本生理学会大会, Mar. 2012. Tetsuya Shiuchi, Sachiko Chikahisa, Hiroaki Fujihara, Akari Futami and Hiroyoshi Sei : Effect of differential feeding rhythm on insulin sensitivity and its mechanism, 日本生理学会, Mar. 2012. 近久 幸子, 西野 精治 : 脳とこころのプライマリ・ケア 3章 神経伝達物質と睡眠, 株式会社シナジー出版, 2012年6月. Hiroyoshi Sei : Blood pressure surges in REM sleep: A mini review., Pathophysiology, Vol.19, No.4, 233-241, 2012. T Ogawa, Hiroyoshi Sei, H Konishi, N Shishioh-Ikejima and H Kiyama : The absence of somatotroph proliferation during continuous stress is a result of the lack of extracellular signal-regulated kinase 1/2 activation., Journal of Neuroendocrinology, Vol.24, No.10, 1335-1345, 2012. 志内 哲也 : エネルギー代謝調節における中枢と末梢臓器間のクロストーク, 日本臨牀, Vol.70, 69-73, 2012年5月. 勢井 宏義, 北岡 和義, 近久 幸子 : Sleep regulatory mechanisms, 日本臨牀, Vol.70, No.7, 1133-1138, 2012年7月. 志内 哲也 : 骨格筋と中枢を中心とした代謝連関作用, 血管医学, Vol.14, No.1, 45-52, 2013年3月. Sachiko Chikahisa, Tohru Kodama, Yohoei Sagawa, Yuji Ishimaru, Hiroyoshi Sei and Seiji Nishino : Effects of icv administration of a mast cell histamine release enhancer on sleep/wake in wild-type and mast cell deficient mice, Sleep 2012: 26th Annual Meeting of the Associated Professional Sleep Societies, Boston, Jun. 2012. Noriyuki Shimizu, Sachiko Chikahisa, Yohei Iwaki, Kazuyoshi Kitaoka and Hiroyoshi Sei : Male adult mice with low birth weight show an increased sleep pressure, Sleep 2012: 26th Annual Meeting of the Associated Professional Sleep Societies, Boston, Jun. 2012. 二見 明香里, 阪上 浩, 原田 永勝, 志内 哲也, 中屋 豊 : 中枢神経系におけるグレリンの摂食と運動調節経路の解析, 糖尿病, Vol.55, No.Suppl.1, S-300, 2012年5月. 戸田 知得, 志内 哲也, 箕越 靖彦 : レプチンは視床下部腹内側核の異なるシグナル伝達因子を介して骨格筋および肝臓のインスリン感受性を高める, 第9回 GPCR研究会, 2012年5月. 近久 幸子, 勢井 宏義 : 脳内脂質代謝と睡眠, 日本睡眠学会第37回定期学術集会, 2012年6月. 唐 麗君, 志内 哲也, 箕越 靖彦 : 白色脂肪組織TNFαのmRNA発現に及ぼすAgRPおよび交感神経の調節作用, 第33回日本肥満学会, 2012年10月. 志内 哲也, 近久 幸子, 藤原 広明, 二見 明香理, 勢井 宏義 : 摂食リズムの乱れによるインスリン抵抗性発症と中枢性代謝調節機構との関連, 第33回日本肥満学会, 2012年10月. 志内 哲也 : 骨格筋と中枢における代謝連関作用, 第16回日本心血管内分泌代謝学会, 2012年11月. 志内 哲也 : 骨格筋代謝の中枢性制御, 第24回 身心統合BAMISセミナー, 2012年12月. Yasuhiko Minokoshi, 志内 哲也, Shiki Okamoto : Hypothalamic Orexin Stimulates Feeding-Associated Glucose Utilization in Skeletal Muscle via Sympathetic Nervous System, 第90回日本生理学会, 2013年3月. Tetsuya Shiuchi, Akari Futami, Sachiko Chikahisa, Kanna Oura, Hiroaki Fujihara and Hiroyoshi Sei : Effect of feeding rhythm on hypothalamic regulation of energy metabolism, 第90回日本生理学会, Mar. 2013. 近久 幸子 : 睡眠障害 知る診る治す 2章 睡眠のメカニズム,3章 ノンレム・レム期の脳の働き,4章 睡眠リズムの変化のメカニズム, 株式会社 メジカルビュー社, 2014年3月. A Genshiro Sunagawa, Hiroyoshi Sei, Shigeki Shimba, Yoshihiro Urade and R Hiroki Ueda : FASTER: an unsupervised fully automated sleep staging method for mice., Genes to Cells, Vol.18, No.6, 502-518, 2013. Noriyuki Shimizu, Sachiko Chikahisa, Yuina Nishi, Saki Harada, Yohei Iwaki, Hiroaki Fujihara, Kazuyoshi Kitaoka, Tetsuya Shiuchi and Hiroyoshi Sei : Maternal Dietary Restriction Alters Offspring's Sleep Homeostasis., PLoS ONE, Vol.8, No.5, e64263, 2013. Chitoku Toda, Tetsuya Shiuchi, Hiroaki Kageyama, Shiki Okamoto, Eulalia A. Coutinho, Tatsuya Sato, Yuko Okamatsu-Ogura, Shigefumi Yokota, Kazuyo Takagi, Lijun Tang, Kumiko Saito, Seiji Shioda and Yasuhiko Minokoshi : Extracellular SignalRegulated Kinase in the Ventromedial Hypothalamus Mediates Leptin-Induced Glucose Uptake in Red-Type Skeletal Muscle, Diabetes, Vol.62, No.7, 2295-2307, 2013. Kazuyoshi Kitaoka, Noriyuki Shimizu, Koji Ono, Sachiko Chikahisa, Madoka Nakagomi, Koichi Shudo, Kazunori Ishimura, Hiroyoshi Sei and Kazuo Yoshizaki : The retinoic acid receptor agonist Am80 increases hippocampal ADAM10 in aged SAMP8 mice, Neuropharmacology, Vol.72, 58-65, 2013. Sachiko Chikahisa, Tohru Kodama, Atsushi Soya, Yohei Sagawa, Yuji Ishimaru, Hiroyoshi Sei and Seiji Nishino : Histamine from brain resident MAST cells promotes wakefulness and modulates behavioral states., PLoS ONE, Vol.8, No.10, e78434, 2013. Yuki Hosono, Kazuyoshi Kitaoka, Ryo Urushihara, Hiroyoshi Sei and Yohsuke Kinouchi : Anxiety affects amplitudes of red and green color-elicited flash visual evoked potentials in humans, The Journal of Medical Investigation : JMI, Vol.61, No.1,2, 79-83, 2014. Saki Harada, Sachiko Chikahisa, Noriyuki Shimizu, Tetsuya Shiuchi and Hiroyoshi Sei : Does sleep loss induce diabetes?, 49th EASD, Sep. 2013. Tetsuya Shiuchi, Sachiko Chikahisa, Kanna Oura, Noriyuki Shimizu and Hiroyoshi Sei : Different feeding rhythm influences hypothalamic regulation of energy metabolism in skeletal muscle, EASD, Sep. 2013. Kanna Oura, Tetsuya Shiuchi, Noriyuki Shimizu, Sachiko Chikahisa and Hiroyoshi Sei : Effect of feeding rhythm on sleep/wake regulation, EASD, Sep. 2013. Sachiko Chikahisa, Noriyuki Shimizu, Tetsuya Shiuchi and Hiroyoshi Sei : Ketone bodies regulate sleep homeostasis, Neuroscience 2013, Nov. 2013. Sachiko Chikahisa, Noriyuki Shimizu, Tetsuya Shiuchi and Hiroyoshi Sei : Ketone bodies in the brain regulate sleep homeostasis in mice, Gordon Research Conference on Sleep Regulation and Function, Galveston, USA, Mar. 2014. 志内 哲也, 近久 幸子, 大浦 寛奈, 二見 明香理, 藤原 広明, 勢井 宏義 : 摂食スケジュールの違いによる生体内エネルギー代謝循環の変動, 第56回日本糖尿病学会, 2013年5月. 近久 幸子, 清水 紀之, 志内 哲也, 藤原 広明, 勢井 宏義 : 脳内ケトン体代謝が睡眠ホメオスタシスへ及ぼす影響, 日本睡眠学会第38回定期学術集会, 2013年6月. 近久 幸子, 勢井 宏義 : 中枢脂質代謝と睡眠, 日本睡眠学会第38回定期学術集会, 2013年6月. 志内 哲也 : 社会敗北性ストレスに対する運動の影響, 第6回脳・神経・内分泌から運動の意義を考える会, 2013年9月. 志内 哲也, 大浦 寛奈, 清水 紀之, 近久 幸子, 勢井 宏義 : 異なる摂食スケジュールが睡眠に与える影響, 第34回日本肥満学会, 2013年10月. 清水 紀之, 近久 幸子, 志内 哲也, 北岡 和義, 勢井 宏義 : 妊娠期母親マウスの摂餌制限が仔マウスの睡眠調節機構に与える影響, 第65回日本生理学会中国四国地方会, 2013年11月. 四宮 圭, 西 結奈, 清水 紀之, 近久 幸子, 志内 哲也, 勢井 宏義 : 妊娠中の高脂肪食が仔マウスの脳機能に与える影響, 第65回日本生理学会中国四国地方会, 2013年11月. Airi Otsuka, Tetsuya Shiuchi, Kanna Oura, Noriyuki Shimizu, Sachiko Chikahisa and Hiroyoshi Sei : Effect of feeding pattern on sleep depth, 91th Annual Meeting of Physiological Society of Japan, Mar. 2014. Sachiko Chikahisa, Noriyuki Shimizu, Tetsuya Shiuchi and HIroyoshi Sei : Central ketone bodies regulate sleep homeostasis in mice, 91th Annual Meeting of Physiological Society of Japan, Mar. 2014. Tetsuya Shiuchi, Airi Otsuka, Noriyuki Shimizu, Sachiko Chikahisa and Hiroyoshi Sei : Evening-based feeding habit impaires insulin sensitivity via central AgRP, 91th Annual Meeting of Physiological Society of Japan, Mar. 2014. Sachiko Chikahisa, Noriyuki Shimizu, Tetsuya Shiuchi and Hiroyoshi Sei : Ketone body metabolism and sleep homeostasis in mice., Neuropharmacology, Vol.79, 399-404, 2014. Yumiko Miyatake, Tetsuya Shiuchi, Tomoyo Ueta, Yasuko Taniguchi, Akari Futami, Fukiko Sato, Tadahiro Kitamura, Rie Tsutsumi, Nagakatsu Harada, Yutaka Nakaya and Hiroshi Sakaue : Intracerebroventricular injection of adiponectin regulates locomotor activity in rats, The Journal of Medical Investigation : JMI, Vol.62, No.3-4, 199-203, 2015. 志内 哲也 : 視床下部とメタボリックシンドロームの改善, 体育の科学, Vol.64, No.5, 331-338, 2014年5月. Tetsuya Shiuchi : Feeding rhythm during active phase influences hypothalamic regulation of energy metabolism in skeletal muscle, Tokyo Translational Therapeutics Meeting "Homeodynamics in Clocks, Sleep and Metabolism", Sep. 2014. Sachiko Chikahisa, Saki Harada, Noriyuki Shimizu, Tetsuya Shiuchi and Hiroyoshi Sei : Sleep quality affects glucose homeostasis in a mouse model, Homeodynamics in Clocks, Sleep and Metabolism, Tokyo Translational Therapeutics Meeting, Sep. 2014. Tetsuya Shiuchi, Airi Otuska, Sachiko Chikahisa, Noriyuki Shimizu and Hiroyoshi Sei : Hypothalamic AgRP-mediated energy metabolism in skeletal muscle is a critical regulatory system in feeding rhythm-induced insulin resistance, Experimental Biology 2015, Boston, Mar. 2015. 志内 哲也, 大塚 愛理, 近久 幸子, 勢井 宏義 : 摂食リズムの乱れにより発症するインスリン抵抗性は中枢AgRPを介する, 第57回日本糖尿病学会, 2014年5月. 宮武 由美子, 佐藤 蕗子, 原田 永勝, 勢井 宏義, 志内 哲也, 中屋 豊, 阪上 浩 : Adiponectin・Leptinによる中枢性運動制御部位の同定, 第57回日本糖尿病学会, 2014年5月. 大塚 愛理, 大浦 寛奈, 志内 哲也, 勢井 宏義, 寺尾 純二 : 摂食リズムの変動による睡眠深度の変化, 第68回日本栄養・食糧学会, 2014年5月. 志内 哲也, 大塚 愛理, 近久 幸子, 勢井 宏義 : 摂食リズムの乱れにより発症するインスリン抵抗性は中枢AgRPを介する, 第57回日本糖尿病学会, 2014年5月. 近久 幸子, 児玉 亨, 征矢 敦至, 佐川 洋平, 石丸 雄二, 勢井 宏義, 西野 精治 : 脳内肥満細胞の睡眠覚醒調節における役割, 日本睡眠学会第39回定期学術集会, 2014年7月. 近久 幸子, 勢井 宏義 : 中枢ケトン体代謝による睡眠ホメオスタシス調節, 日本睡眠学会第39回定期学術集会, 2014年7月. Tetsuya Shiuchi, Airi Otsuka, Kanna Oura, Noriyuki Shimizu, Sachiko Chikahisa and Hiroyoshi Sei : Different feeding schedule affects sleep pressure, The 37th Annual Meeting of the Japan Neuroscience Society, Sep. 2014. 志内 哲也, 大塚 愛理 : 社会敗北性ストレスに対する運動の影響, 第69回日本体力医学会大会, 2014年9月. Airi Otsuka, Tetsuya Shiuchi, Sachiko Chikahisa, Junji Terao and Hiroyoshi Sei : Effect of restricted high fat diet intake on behavior induced by social defeat stress, The 37th Annual Meeting of the Japan Neuroscience Society, Sep. 2014. 志内 哲也 : 摂食リズムが中枢性代謝調節機構に及ぼす影響, 生理研研究会「臓器相関による生体制御システムとその変容の仕組み」, 2014年9月. 志内 哲也, 大塚 愛理, 近久 幸子, 勢井 宏義 : 摂食リズムの変化は中枢AgRPを介して骨格筋のインスリン感受性に影響を与える, 第35回日本肥満学会, 2014年10月. Airi Otsuka, Tetsuya Shiuchi, Sachiko Chikahisa, Junji Terao and Hiroyoshi Sei : Physical exercise reduces social avoidance induced by defeated stress, 92nd Annual Meeting of The Physiological Society of Japan, Mar. 2015. Tetsuya Shiuchi : Hypothalamic regulation of energy metabolism by feeding rhythm, 92nd Annual Meeting of The Physiological Society of Japan, Mar. 2015. Sachiko Chikahisa and Hiroyoshi Sei : The role of PPARs and ketone body metabolism in the regulation of sleep homeostasis, 92nd Annual Meeting of The Physiological Society of Japan, Mar. 2015. 志内 哲也 : 摂食リズムと視床下部ー骨格筋連関を介した血糖制御, 日本薬学会第135年会, 2015年3月.