! Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Shoji Kagami, Yuki Izawa, Yoshiko Fujita, Nermin Ali, Yasuhisa Kanematsu, Kazunori Toida, Kazunori Ishimura and Toshiaki Tamaki : Src and Cas are essentially but differentially involved in angiotensin II-stimulated migration of vascular smooth muscle cell via extracellur signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase activation, Molecular Pharmacology, Vol.65, No.4, 832-841, 2004. Yuki Suzaki, Masanori Yoshizumi, Shoji Kagami, Akira Nishiyama, Yuichi Ozawa, Moe Kyaw, Yuki Izawa, Yasuhisa Kanematsu, Koichiro Tsuchiya and Toshiaki Tamaki : BMK1 is activated in glomeruli of diabetic rats and in mesangial cells by high glucose conditions, Kidney International, Vol.65, No.5, 1749-1760, 2004. Keisuke Ishizawa, Masanori Yoshizumi, Koichiro Tsuchiya, Hitoshi Houchi, Kazuo Minakuchi, Yuki Izawa, Yasuhisa Kanematsu, Shoji Kagami, Masao Hirose and Toshiaki Tamaki : Dual effects of endothelin-1 (1-31): induction of mesangial cell migration and facilitation of monocyte recruitment through monocyte chemoattractant protein-1 production by mesangial cells, Hypertension Research, Vol.27, No.6, 433-440, 2004. Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Yuki Izawa, Yasuhisa Kanematsu and Toshiaki Tamaki : Atheroprotective effects of antioxidants through inhibition of mitogen-activated protein kinases, Acta Pharmacologica Sinica, Vol.25, No.8, 977-985, 2004. Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Yuki Izawa, Yasuhisa Kanematsu, Yoshiko Fujita, Nermin Ali, Keisuke Ishizawa, Aiko Yamauchi and Toshiaki Tamaki : Antioxidant effects of stereoisomers of N-acetylcysteine (NAC), L-NAC and D-NAC, on angiotensin II-stimulated MAP kinase activation and vascular smooth muscle cell proliferation, Journal of Pharmacological Sciences, Vol.95, No.4, 483-486, 2004. Kaori Akai, Koichiro Tsuchiya, Akira Tokumura, Kentaro Kogure, Satoru Ueno, Akira Shibata, Toshiaki Tamaki and Kenji Fukuzawa : Ability of ferric nitrilotriacetate complex with three pH-dependent conformations to induce lipid peroxidation., Free Radical Research, Vol.38, No.9, 951-962, 2004. Koichiro Tsuchiya, Yoshiharu Takiguchi, Masumi Okamoto, Yuki Izawa, Yasuhisa Kanematsu, Masanori Yoshizumi and Toshiaki Tamaki : Malfunction of vascular control in lifestyle-related diseases : formation of systemic hemoglobin-nitric oxide Complex(HbNO) From Dietary Nitrite, Journal of Pharmacological Sciences, Vol.96, No.4, 395-400, 2004. Masumi Okamoto, Koichiro Tsuchiya, Yasuhisa Kanematsu, Yuki Izawa, Masanori Yoshizumi, Susumu Kagawa and Toshiaki Tamaki : Nitrite-derived nitric oxide formation following ischemia-reperfusion injyury in kidney., American Journal of Physiology, Renal Physiology, Vol.288, No.1, 182-187, 2005. 吉栖 正典, 土屋 浩一郎, 兼松 康久, 玉置 俊晃 : Ⅴ.エンドセリン 薬理作用と生理作用 心筋障害作用, 日本臨牀, Vol.62, No.9, 622-625, 2004年. Shuji Kondo, Maki Shimizu, Koichiro Tsuchiya, Masanori Yoshizumi, Toshiaki Tamaki, Hiroshi Kawachi, Fujio Shimizu, Quinn T Mark, Lambeth J David, Yasuhiro Kuroda and Shoji Kagami : Add-on the antioxidant, probucol to angiotensin II type I receptor antagonist (ARB) arrests the progressive, St. Louis, MO, Oct. 2004. Toshiaki Tamaki, Masumi Okamoto, Yasuhisa Kanematsu, Yuki Izawa, Shoji Kagami, Shuji Kondo, Maki Shimizu, Masanori Yoshizumi and Koichiro Tsuchiya : Nitrite-derived nitric oxide formation following ischemia-reperfusion injury in rat kidney, 37th ASN annual meeting, St. Louis, MO, Oct. 2004. 石上 まみ, 池平 しのぶ, 三好 真紀, 土屋 浩一郎, 滝口 祥令, 高石 喜久 : 竹粉末のロペラミン誘発便秘改善作用, 第43回日本薬学会・日本病院薬剤師会中国四国支部学術大会, 2004年11月. 堀長 志帆, 吉村 祥穂, 村田 有希, 土屋 浩一郎, 峰松 敏彦, 川添 和義, 高石 喜久, 福井 裕行 : 苦参,小青竜湯のアレルギー疾患関連遺伝子発現機構への影響, 第43回日本薬学会・日本病院薬剤師会中国四国支部学術大会, 2004年11月. 滝口 祥令 : 心臓・血管系疾患, 株式会社 南山堂, 東京, 2005年4月. 生田 雅子, 会田 真規, 石澤 啓介, 水口 和生, 土屋 浩一郎, 木原 勝, 山内 あい子 : 徳島大学病院におけるTPN処方設計支援ソフトの使用評価と改良, 医療薬学, Vol.31, No.4, 279-286, 2005年. Koichiro Tsuchiya, Yasuhisa Kanematsu, Masanori Yoshizumi, Hideki Ohnishi, Kazuyoshi Kirima, Yuki Izawa, Michiyo Shikishima, Tatsuhiro Ishida, Shuji Kondo, Shoji Kagami, Yoshiharu Takiguchi and Toshiaki Tamaki : Nitrite is an alternative source of NO in vivo, American Journal of Physiology, Heart and Circulatory Physiology, Vol.288, No.5, H2163-H2170, 2005. Ali Nermin, Masanori Yoshizumi, Yoshiko Fujita, Yuki Izawa, Yasuhisa Kanematsu, Keisuke Ishizawa, Koichiro Tsuchiya, Seiji Yano, Saburo Sone and Toshiaki Tamaki : A Novel Src Kinase Inhibitor, M475271, Inhibits VEGF-Induced Human Umbilical Vein Endothelial Cell Proliferation and Migration, Journal of Pharmacological Sciences, Vol.98, No.2, 130-141, 2005. Keisuke Ishizawa, Yuki Izawa, Hiroyuki Ito, Chieko Miki, Kayoko Miyama, Yoshiko Fujita, Yasuhisa Kanematsu, Koichiro Tsuchiya, Toshiaki Tamaki, Akira Nishiyama and Masanori Yoshizumi : Aldosterone stimulates vascular smooth muscle cell proliferation via big mitoten-activated protein kinase 1 activation, Hypertension, Vol.46, No.4, 1046-1052, 2005. Yoshihiko Fujita, Koichiro Tsuchiya, Shinji Abe, Yohiharu Takiguchi, Shin-ichi Kubo and Hiromu Sakurai : Estimation of the age of human bloodstains by electron paramagnetic resonance spectroscopy: Long-term controlled experiment on the effects of environmental factors, Forensic Science International, Vol.152, No.1, 39-43, 2005. Yuki Izawa, Masanori Yoshizumi, Keisuke Ishizawa, Yoshiko Fujita, Shuji Kondo, Shoji Kagami, Kazuyoshi Kawazoe, Koichiro Tsuchiya, Shuhei Tomita and Toshiaki Tamaki : ERK1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells, Experimental Cell Research, Vol.308, No.2, 291-299, 2005. Koichiro Tsuchiya, Kaori Akai, Akira Tokumura, Shinji Abe, Toshiaki Tamaki, Yoshiharu Takiguchi and Kenji Fukuzawa : Oxygen radical photo-induced by ferric nitrilotriacetate complex, Biochimica et Biophysica Acta (BBA) - General Subjects, Vol.1725, No.1, 111-119, 2005. 田島 壮一郎, 土屋 浩一郎, 大西 秀樹, 兼松 康久, 玉置 俊晃, Ronald Mason, 滝口 祥令 : ラジカル認識抗体を用いた酸化ストレス由来プロテインラジカル検出法, 日本薬理学雑誌, Vol.126, No.4, 246-249, 2005年. Otsuka Toshihiro, Keisuke Izumi, Itsuo Tokunaga, Takako Gotohda, Ipposhi Kaneshige, Yoshiharu Takiguchi, Kaneda Shinya, Nobuo Satake, Takamasa Ohnishi, Seiki Tashiro and Mitsuo Shimada : Prevention of lethal hepatic injury in Long-Evans Cinnamon(LEC) rats by D-galactosamine hydrochloride, The Journal of Medical Investigation : JMI, Vol.53, No.1-2, 81-86, 2006. Yoshiko Fujita, Yuki Izawa, Nermin Ali, Koichiro Tsuchiya, Shuichi Hamano, Toshiaki Tamaki and Masanori Yoshizumi : Pramipexole protects against H2O2-induced PC12 cell death, Naunyn-Schmiedeberg's Archives of Pharmacology, Vol.372, No.4, 257-266, 2006. Shuji Kondo, Maki Shimizu, Maki Urushihara, Koichiro Tsuchiya, Masanori Yoshizumi, Toshiaki Tamaki, Akira Nishiyama, Hiroshi Kawachi, Fujio Shimizu, Quinn T. Mark, Lambeth J. David and Shoji Kagami : Addition of the antioxidant probucol to angiotensin II type I receptor antagonist arrests progression mesangioproliferative glomerulonephritis in the rat, Journal of the American Society of Nephrology, Vol.17, No.3, 783-794, 2006. Yoshiko Fujita, Masanori Yoshizumi, Yuki Izawa, Nermin Ali, Yasuhisa Kanematsu, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki : Transactivation of fetal liver kinase-1/kinase-insert domain-containing receptor by lysophosphatidylcholine induces vascular endothelial cell proliferation., Endocrinology, Vol.147, No.3, 1377-1385, 2006. 兼松 康久, 土屋 浩一郎, 玉置 俊晃 : 生体内における亜硝酸由来のNO産生と,その循環動態への作用検討, 血管, Vol.28, No.2, 39-45, 2005年. Masanori Yoshizumi, Keisuke Ishizawa, Yuki Izawa, Chieko Miki, Yoshiko Fujita, Yasuhisa Kanematsu, Koichiro Tsuchiya and Toshiaki Tamaki : Aldosterone stimulates vascular smooth muscle cell proliferation through big mitogen-activated protein kinase1 activation, 16th scientific meeting of the interamerican society of hypertension, Cancun, Mexico, Apr. 2005. Toshiaki Tamaki, Masumi Okamoto, Yasuhisa Kanematsu, Yuki Izawa, Shoji Kagami, Shuji Kondo, Masanori Yoshizumi and Koichiro Tsuchiya : Dietary dose of nitrite attenuates L-NAME-induced renal injury in rats, 3rd World Congress of Nephrology, Singapore, Jun. 2005. Keisuke Ishizawa, Rika Sugimoto, Yuki Izawa, Kazuo Minakuchi, Koichiro Tsuchiya and Toshiaki Tamaki : Adiponectin inhibits PDGF-induced migration and proliferation in rat mesangial cells, 第10回アディポサイエンス研究会シンポジウム(第10回記念国際シンポジウム), Osaka, Aug. 2005. Koichiro Tsuchiya, Kaori Akai, Akira Tokumura, Shinji Abe, Toshiaki Tamaki, Yoshiharu Takiguchi and Kenji Fukuzawa : Oxygen Radicals Photo-induced by Ferric Nitrilotriacetate(FE-NTA) Complex, EPR 2005, Columbus, OH, Sep. 2005. Soichiro Tajima, Koichiro Tsuchiya, Hideki Ohnishi, Yasuhisa Kanematsu, Masanori Yoshizumi, Toshiaki Tamaki, Mason P. Ronald and Yoshiharu Takiguchi : Immunochemical Dection of Thioredoxin-Derived Radicals Formed by Reaction with Hydrogen Peroxide, EPR 2005, Columbus, OH, Sep. 2005. Keisuke Ishizawa, Rika Sugimoto, Yuki Izawa, Koichiro Tsuchiya, Kazuo Minakuchi and Toshiaki Tamaki : The inhibitory effect of adiponectin on migration and proliferation induced by PDGF in rat mesangial cells, 38th ASN annual meeting, Philadelphia, Nov. 2005. Toshiaki Tamaki, Yasuhisa Kanematsu, Yuki Izawa, Hideki Ohnishi, Yuki Motobayashi, Shoji Kagami and Koichiro Tsuchiya : Chronic oral administration of nitrite restores circulating NO level and improves renal injury in L-NAME treated rats, 38th ASN annual meeting, Philadelphia, Nov. 2005. Yasuhisa Kanematsu, Koichiro Tsuchiya, Hideki Onishi, Yuki Motobayashi, Yuki Izawa, Manabu Ishihara, Keisuke Ishizawa, Shinji Abe, Kazuyoshi Kawazoe and Toshiaki Tamaki : Effects of angiotensin II type 1 receptor blockade on the systemic blood nitric oxide dynamics in Nω-nitro-L-arginine methyl ester-treated rats, Hypertension Research, Vol.29, No.5, 369-374, 2006. F.A. Ramos, Yoshihisa Takaishi, M. Shirotori, Y. Kawaguchi, Koichiro Tsuchiya, Hirofumi Shibata, Tomihiko Higuti, T. Tadokoro and M. Takeuchi : Antibacterial and Antioxidant Activities of Quercetin Oxidation Products from Yellow Onion (Alliu cepa) Skin, Journal of Agricultural and Food Chemistry, Vol.54, No.10, 3551-3357, 2006. Hiroyuki Nakagawa, Yoshihisa Takaishi, Naonobu Tanaka, Koichiro Tsuchiya, Hirofumi Shibata and Tomihiko Higuti : Chemical Constituents from the Peels of Citrus sudachi, Journal of Natural Products, Vol.69, No.8, 1177-1179, 2006. 川添 仁, 久保 智美, 飯原 なおみ, 土居 智明, 奥條 真紀子, 福岡 憲泰, 藤本 さとし, 金地 伸拓, 坂東 修二, 石田 俊彦, 滝口 祥令, 芳地 一 : 患者参加型癌化学療法副作用モニタリング, --- 患者の治療参加と情報の共有化 ---, 薬学雑誌, Vol.126, No.8, 629-642, 2006年. Shinji Abe, Hideki Ohnishi, Koichiro Tsuchiya, Keisuke Ishizawa, Mayumi Torii, Yasuhisa Kanematsu, Kazuyoshi Kawazoe, Kazuo Minakuchi, Masanori Yoshizumi and Toshiaki Tamaki : Calcium and reactive oxygen species mediated Zn2+-induced apoptosis in PC12 cells, Journal of Pharmacological Sciences, Vol.102, No.1, 103-111, 2006. Ali Nermin, Masanori Yoshizumi, Seiji Yano, Saburo Sone, Hideki Ohnishi, Keisuke Ishizawa, Yasuhisa Kanematsu, Koichiro Tsuchiya and Toshiaki Tamaki : The novel Src kinase inhibitor M475271 inhibits VEGF-induced vascular endothelial-cadherin and β-catenin phosphorylation but increases their association, Journal of Pharmacological Sciences, Vol.102, No.1, 112-120, 2006. Yoshichika Kawai, Hitomi Kiyokawa, Yuki Kimura, Yoji Kato, Koichiro Tsuchiya and Junji Terao : Hypochlorous acid-derived modification of phospholipids: characterization of aminophospholipids as regulatory molecules for lipid peroxidation., Biochemistry, Vol.45, No.47, 14201-14211, 2006. Hitoshi Kawazoe, Yoshiharu Takiguchi, Hiroaki Tanaka, Noriyasu Fukuoka, Hiroaki Ohnishi, Toshihiko Ishida and Hitoshi Houchi : Change of the blood concentration of tacrolimus after the switch from fluconazole to variconazole in patients receiving allogeneic hematopoietic stem cell transplantation, Biological & Pharmaceutical Bulletin, Vol.29, No.12, 2528-2531, 2006. Deliorman Didem Orhan, Fatma Ergun, Erdem Yesilada, Koichiro Tsuchiya, Yoshihisa Takaishi and Kazuyoshi Kawazoe : Antioxidant activity of two flavonol glycosides from Cirsium hypoleucum DC. through bioassay-guided fractionation, Turkish Journal of Pharmaceutical Sciences, Vol.4, No.1, 1-14, 2007. Kenji Fukuzawa, Akira Shibata, Koichiro Tsuchiya, Akira Tokumura, H. Ichikawa and Jansuz M. Gebicki : Colored complex of ferric-xylenol orange/phosphatidylcholine vesicle in the Fox assay, XIII the Biennial Meeting of the Society for Free Radical Research International, Davos, Aug. 2006. Koichiro Tsuchiya, Yasuhisa Kanematsu, Keisuke Ishizawa, Shinji Abe, Hideki Ohnishi, Soichiro Tajima, Kazuyoshi Kawazoe, Yoshiharu Takiguchi and Toshiaki Tamaki : Dietary nitrite is an alternative source of NO in vivo, International Society for Radical Research 13th Biennial Congress, Davos, Switzerland, Aug. 2006. Hideki Ohnishi, Koichiro Tsuchiya, Yasuhisa Kanematsu, Shinji Abe, Soichiro Tajima and Toshiaki Tamaki : Effects of quercetin on NO production from nitrite at physiological conditions, 20th Scientific Meeting of the International Soiciety of Hypertension, Fukuoka, Japan, Oct. 2006. Koichiro Tsuchiya, Yuya Horinouchi, Yasuhisa Kanematsu, Shinji Abe, Hideki Ohnishi, Soichiro Tajima, Keisuke Ishizawa, Toshiaki Tamaki and Yoshiharu Takiguchi : Production of nitrosonifedipine radical from nifedipine and its antioxidative activity in cultured cells, 13th annual meeting of society of free radical and biology of medicine, Denver, Nov. 2006. Keisuke Ishizawa, Erika Miki, Arisa Hironaga, Koichiro Tsuchiya, Maki Urushihara, Shoji Kagami and Toshiaki Tamaki : Angiotensin II receptor blocker inhibits PDGF-induced cell migration in rat mesangial cells, 39th ASN annual meeting 2006, San Diego, Nov. 2006. 川添 和義, 松村 敏彦, 黒川 ふみ, 榊原 啓之, 石澤 啓介, 土屋 浩一郎, 清水 寛, 寺尾 純二, 玉置 俊晃, 水口 和生 : ラット強制水泳試験による漢方薬の抗うつ作用評価, 第109回日本薬理学会近畿部会, 30, 2006年6月. 田中 直伸, 中川 博之, 橋田 和佳, 佐藤 昌俊, 奥瀬 由惟, 田岡 千明, 岩永 智史, 土屋 浩一郎, 高石 喜久 : スダチCitrus sudachi)の含有成分並びに血糖値上昇抑制作用について, 第一回食品薬学シンポジウム, 2006年10月. 松村 敏彦, 宮本 由加里, 黒川 ふみ, 阿部 真治, 榊原 啓之, 石澤 啓介, 土屋 浩一郎, 清水 寛, 寺尾 純二, 玉置 俊晃, 川添 和義, 水口 和生 : ラット強制水泳試験における漢方薬の抗うつ作用の検討, 第45回日本薬学会・日本病院薬剤師会中国四国支部学術大会, 125, 2006年10月. 神谷 昌樹, 中本 亜樹, 河村 知志, 根本 尚夫, 土屋 浩一郎, 滝口 祥令 : 高脂血症治療薬・フェノフィブラートのBGL Modificationによる中性脂肪低下効果の検討, 日本薬学会 第127年会, Vol.31-0567, 2007年3月. Hitoshi Kawazoe, Yoshiharu Takiguchi, Hiroaki Tanaka, Chiaki Doi, Noriyasu Fukuoka, Nobuhiro Kanaji, Shuji Bandoh, Toshihiko Ishida and Hitoshi Houchi : Preventive effects of low-dose dexamethasone for delayed adverse events induced by carboplatin-based combination chemotherapy, Journal of the Pharmaceutical Society of Japan, Vol.127, No.6, 1001-1006, 2007. 川添 仁, 滝口 祥令, 田中 裕章, 二宮 昌樹, 福岡 憲泰, 大西 宏明, 石田 俊彦, 芳地 一 : 同種造血幹細胞移植患者におけるニューキノロン系抗菌薬による内因性感染の予防効果, --- 骨髄移植,末梢血幹細胞移植,臍帯血移植の比較 ---, 薬学雑誌, Vol.127, No.8, 1301-1307, 2007年. Yuki Izawa, Masanori Yoshizumi, Keisuke Ishizawa, Yoshiko Fujita, Shuji Kondo, Shoji Kagami, Kazuyoshi Kawazoe, Koichiro Tsuchiya, Shuhei Tomita and Toshiaki Tamaki : Big mitogen-activated protein kinase 1 (BMK1)/extracellular signal regulated kinase 5 (ERK5) is involved in platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell migration, Hypertension Research, Vol.30, No.11, 1107-1117, 2007. Koichiro Tsuchiya, Satoshi Iwanaga, Hideki Ohnishi, Yayoi Fukuhara, Chiaki Taoka, Soichiro Tajima, Yuya Horinouchi and Toshiaki Tamaki : In vivo and in vitro studies on NO formation from iron-quercetin-nitrite complexes, Second International Role of Nitrite in Physiology, Pathophysiology and Therapeutics Meeting, Bethesda, Maryland, Sep. 2007. Keisuke Ishizawa, Narantungalag Dorjsuren, Yuki Izawa-Ishizawa, Teppei Tsuneishi, Yuki Motobayashi, Hideki Ohnishi, Kunihisa Yamaguchi, Koichiro Tsuchiya and Toshiaki Tamaki : Inhibitory effects of olmesartan on TNF-α-induced cytotoxicity in human glomerular endothelial cells, 40th ASN annual meeting, San Francisco, Nov. 2007. 佐野 真純, 德村 彰, 土屋 浩一郎, 柴田 瑩, 福澤 健治 : 過酸化脂質の簡易比色定量法:発色成分 [キシレノールオレンジFe3+錯体ー膜ホスファチジルコリン] 複合体の性質, 日本過酸化脂質フリーラジカル学会第31回大会, 2007年6月. 田岡 千明, 土屋 浩一郎, 神谷 昌樹, 根本 尚夫, 石澤 啓介, 山口 邦久, 滝口 祥令, 玉置 俊晃 : 水溶性Fenofibrate製剤の作成と中性脂肪低下作用の検討, 第111回 日本薬理学会近畿部会, 81, 2007年6月. 東 満美, 日野出 晴美, 柏田 良樹, 吉田 昌裕, 山﨑 尚志, 土屋 浩一郎, 山内 あい子, 柴田 洋文, 新垣 尚捷, 滝口 祥令, 荒木 勉, 吉村 好之, 姫田 敏樹, 石田 竜弘, 辻 大輔, 木原 勝 : 徳島大学薬学部OSCEトライアル実施体制の確立と検証, 第17回 日本医療薬学会年会, 2007年9月.