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Wenhao Li, Tatsuhiro Ishida, Rieko Tachibana, Mohamad Radwan Almofti, Xinyu Wang and Hiroshi Kiwada : Cell type-specific gene expression, mediated by TFL-3, a cationic liposomal vector, is controlled by a post-transcription process of delivered plasmid DNA, International Journal of Pharmaceutics, Vol.276, No.1-2, 67-74, 2004.
石田 竜弘, 高梨 吉裕, 際田 弘志 : 脳脊髄腔内直接投与可能なDDSの開発とその脳保護効果, 月刊 薬事, Vol.46, No.7, 1333-1338, 2004年6月.
石田 竜弘 : 脳脊髄腔投与可能なDDSの開発とその脳保護効果の検討, 薬学雑誌, Vol.124, No.8, 541-547, 2004年8月.
石田 竜弘, 際田 弘志 : ポリエチレングリコール表面修飾リポソームの繰り返し投与時に発現するaccelerated blood clearance(ABC)現象, Drug Delivery System, Vol.19, No.6, 495-510, 2004年11月.
石田 竜弘 : リポソームDDSの開発研究, 薬剤学, Vol.65, 28-33, 2005年.
Tatsuhiro Ishida, Masako Ichihara, Shuntarou Kashima, Wang Xinyu and Hiroshi Kiwada : IgM secreted in response to injection of PEGylated liposomes causes accelerated blood clearance of a subsequent dose., 9th Liposome Research Days Conference, Hsinchu, Taiwan, May 2004.
Hiroshi Kiwada and Tatsuhiro Ishida : Immunological responses to nano-drug carriers., The 2nd Japan-Korea Joint Symposium on Drug Delivery and Therapy, Kyoto, May 2004.
Tatsuhiro Ishida, Masako Ichihara, Masae Harada, Shuntarou Kashima, Wang Xinyu and Hiroshi Kiwada : IgM secreted in response to the first injection of PEGylated liposomes involves in induction of the ABC phenomenon., 31st Annual Meeting and Exposition of the Controlled Release Society., Hawaii, Jun. 2004.
石田 竜弘, 際田 弘志 : 第10章医学薬学でのリポソーム応用 3節長期血中滞留性リポソーム, 株式会社エヌ·ティー·エス, 東京, 2005年6月.
石田 竜弘, 際田 弘志 : 第10章医学薬学でのリポソーム応用 1節リポソームと細胞の相互作用, 株式会社エヌ·ティー·エス, 東京, 2005年6月.
Wenhao Li, Tatsuhiro Ishida, Yurie Okada, Naoto Oku and Hiroshi Kiwada : Increased Gene Expression by Cationic Liposomes (TFL-3) in Lung Metastases Following Intravenous Injection, Biological & Pharmaceutical Bulletin, Vol.28, No.4, 701-706, 2005.
Koichiro Tsuchiya, Yasuhisa Kanematsu, Masanori Yoshizumi, Hideki Ohnishi, Kazuyoshi Kirima, Yuki Izawa, Michiyo Shikishima, Tatsuhiro Ishida, Shuji Kondo, Shoji Kagami, Yoshiharu Takiguchi and Toshiaki Tamaki : Nitrite is an alternative source of NO in vivo, American Journal of Physiology, Heart and Circulatory Physiology, Vol.288, No.5, H2163-H2170, 2005.
Wang Xinyu, Tatsuhiro Ishida, Masako Ichihara and Hiroshi Kiwada : Influence of the physicochemical properties of liposomes on the accelerated blood clearance phenomenon in rat, Journal of Controlled Release, Vol.104, No.1, 91-102, 2005.
Tatsuhiro Ishida, Masae Harada, Wang Xinyu, Masako Ichihara, Kenji Irimura and Hiroshi Kiwada : Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: Effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes, Journal of Controlled Release, Vol.105, No.3, 305-317, 2005.
Lap Thi Nguyen, Tatsuhiro Ishida and Hiroshi Kiwada : Gene Expression in Primary Cultured Mouse Hepatocytes with a Cationic Liposomal Vector, TFL-3: Comparison with Rat Hepatocytes, Biological & Pharmaceutical Bulletin, Vol.28, No.8, 1472-1475, 2005.
Tatsuhiro Ishida, Yurie Okada, Tomotaka Kobayashi and Hiroshi Kiwada : Development of pH-sensitive liposomes that efficiently retain encapsulated doxorubicin (DXR) in blood., International Journal of Pharmaceutics, Vol.309, No.1-2, 94-100, 2006.
Tatsuhiro Ishida, Wenhao Liu, Zhung Li and Hiroshi Kiwada : Stimulatory effect of polyethylene glycol (PEG) on gene expression in mouse liver following hydrodynamics-based transfection., The Journal of Gene Medicine, Vol.8, No.3, 324-334, 2006.
Tatsuhiro Ishida, Masako Ichihara, Xinyu Wang, Kenji Yamamoto, Jyunji Kimura, Eiji Majima and Hiroshi Kiwada : Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes., Journal of Controlled Release, Vol.112, No.1, 15-25, 2006.
石田 竜弘, 際田 弘志 : がん治療を目指した機能性リポソームの開発研究, 化学工業, Vol.57, 39-43, 2006年.
Tatsuhiro Ishida, Yoshihiro Takanashi and Hiroshi Kiwada : Safe and efficient drug delivery system with liposomes for intrathecal application of an antivasospastic drug, fasudil., Biological & Pharmaceutical Bulletin, Vol.29, No.3, 397-402, Mar. 2006.
Tatsuhiro Ishida, Kazutaka Atobe, Wang Xinyu and Hiroshi Kiwada : The influence of administration of PEGylated liposomal doxorubicin as a first dose on induction of accelerated blood clearance (ABC) phenomenon., 8th US-Japan symposium on drug delivery systems, Hawaii, Dec. 2005.
Foi Dang, Wenhao Li, LiGo Zhang, M Japasini, Tatsuhiro Ishida, Hiroshi Kiwada, N. Kaji, M. Tokeshi and Yoshinobu Baba : Electrophoretic behavior of plasmid DNA in the presence of various intercalating dyes., Journal of Chromatography. A, Vol.1118, No.2, 218-225, 2006.
Mario Jose Barichello, M. Handa, M. Kisyuku, Taiki Shibata, Tatsuhiro Ishida and Hiroshi Kiwada : Inducing effect of liposomalization on the transdermal delivery of hydrocortisone: creation of a drug supersaturated state., Journal of Controlled Release, Vol.115, No.1, 94-102, 2006.
Tatsuhiro Ishida, Masako Ichihara, Xinyu Wang and Hiroshi Kiwada : Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes., Journal of Controlled Release, Vol.115, No.3, 243-250, 2006.
Tatsuhiro Ishida, Kazutaka Atobe, Xinyu Wang and Hiroshi Kiwada : Accelerated blood clearance of PEGylated liposomes upon repeated injections: Effect of doxorubicin-encapsulation and high-dose first injection., Journal of Controlled Release, Vol.115, No.3, 251-258, 2006.
Tomotaka Kobayashi, Tatsuhiro Ishida, Yurie Okada, Saori Ise, Hideyoshi Harashima and Hiroshi Kiwada : Effect of Transferrin receptor-targeted liposomal doxorubicin in P-glycoprotein-mediated drug resistant tumor cells., International Journal of Pharmaceutics, Vol.329, No.1-2, 94-102, 2007.
Yoshimasa Isakari, Yasuo Harada, Dai Ishikawa, Kuniko Matsumura-Takeda, Shinji Sogo, Tatsuhiro Ishida, Takao Taki and Hiroshi Kiwada : Efficient gene expression in Megakaryocytic cell line using Nucleofection., International Journal of Pharmaceutics, Vol.338, No.1-2, 157-164, 2007.
Xinyu Wang, Tatsuhiro Ishida and Hiroshi Kiwada : Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes., Journal of Controlled Release, Vol.119, No.2, 236-244, 2007.
Tatsuaki Tagami, Mari Jose Barichello, Hiroshi Kikuchi, Tatsuhiro Ishida and Hiroshi Kiwada : The gene-silencing effect of siRNA in cationic lipoplexes is enhanced by incorporating pDNA in the complex., International Journal of Pharmaceutics, Vol.333, No.1-2, 62-69, 2007.
石田 竜弘, 際田 弘志 : リポソームと細胞の相互作用(DDSへの応用), 膜, Vol.32, No.1, 18-24, 2007年1月.
Tatsuhiro Ishida and Hiroshi Kiwada : Immunological responses to liposome carriers, The 1st FIP-APSTJ Joint Work Shop on Gene Delivery, Sapporo, Jul. 2006.
Taisuke Matsuo, Naoshi Yamazaki, Tatsuhiro Ishida, Hiroshi Kiwada, Yasuo Shinohara and Masatoshi Kataoka : Mutant coat proteins of Pf3 bacteriophage as models of membrane proteins and their interactions with lipid bilayer membrane, International symposium on system cell engineering by multi-scale manipulation, Nagoya, Nov. 2006.
石田 竜弘, 際田 弘志 : ポリエチレングリコール修飾リポソーム投与時に生ずるaccelerated blood clearance (ABC)現象, 日本薬学会第127年会,シンポジウムS6, 2007年3月.
三好 弘一, 前澤 博, 足立 昭夫, 佐瀬 卓也, 入倉 奈美子, 桑原 義典, 立花 さやか, 石田 竜弘, 辻 明彦, 英 崇夫, 森賀 俊広, 鬼島 明洋, 誉田 栄一, 岩本 誠司, 佐藤 一雄, 古谷 俊介, 森田 康彦 : 徳島大学アイソトープ総合センターニュース, 徳島大学アイソトープ総合センターニュース, Vol.6, 1-42, 2007年3月.
Lap Thi Nguen, Kazutaka Atobe, Mari Jose Barichello, Tatsuhiro Ishida and Hiroshi Kiwada : Complex formation with plasmid DNA increases the cytotoxicity of cationic liposomes., Biological & Pharmaceutical Bulletin, Vol.30, No.4, 751-757, 2007.
Kazutaka Atobe, Tatsuhiro Ishida, Emi Ishida, Kouichi Hashimoto, Hideo Kobayashi, Jyunko Yasuda, Takanori Aoki, Ken-ichi Obata, Hiroshi Kikuchi, Hidetaka Akita, Tomohiro Asai, Hideyoshi Harashima, Naoto Oku and Hiroshi Kiwada : In vitro efficacy of a sterically stabilized immunoliposomes targeted to membrane type 1 matrix metalloproteinase (MT1-MMP)., Biological & Pharmaceutical Bulletin, Vol.30, No.5, 972-978, 2007.
Hiroto Hatakeyama, Hidetaka Akita, Emi Ishida, Koichi Hashimoto, Hideo Kobayashi, Takanori Aoki, Junko Yasuda, Kenichi Obata, Hiroshi Kikuchi, Tatsuhiro Ishida, Hiroshi Kiwada and Hideyoshi Harashima : Tumor targeting of doxorubicin by anti MT1-MMP antibody-modified PEG liposomes., International Journal of Pharmaceutics, Vol.342, No.1-2, 194-200, 2007.
Tatsuhiro Ishida, Wang Xinyu, Taro Shimizu, Kousuke Nawata and Hiroshi Kiwada : PEGylated liposomes elicit an anti-PEG IgM response in a T-cells independent manner., Journal of Controlled Release, Vol.122, No.3, 349-355, 2007.
T Asai, Y Suzuki, S Matsushita, S Yonezawa, J Yokota, Y Katanasaka, Tatsuhiro Ishida, T Dewa, Hiroshi Kiwada, N Nango and N Oku : Disappearance of the angiogenic potential of endothelial cells caused by Argonaute2 knockdown., Biochemical and Biophysical Research Communications, Vol.368, No.2, 243-248, 2008.
Mario José Barichello, Noriko Yamakawa, Masatoshi Kisyuku, Hiroshi Handa, Taiki Shibata, Tatsuhiro Ishida and Hiroshi Kiwada : Combined effect of liposomalization and addition of glycerol on the transdermal delivery of isosorbide 5-nitrate in rat skin., International Journal of Pharmaceutics, Vol.357, No.1-2, 199-205, 2008.
Tatsuhiro Ishida, Shuntarou Kashima and Hiroshi Kiwada : The contribution of phagocytic activity of liver macrophages to the accelerated blood clearance (ABC) phenomenon of PEGylated liposomes in rats., Journal of Controlled Release, Vol.126, No.2, 162-165, 2008.
石田 竜弘 : デリバリーによる新たな創薬, 薬事日報, Vol.10368, 8, 2007年4月.
石田 竜弘, 際田 弘志 : ポリマー修飾ナノ微粒子投与による免疫活性化に関する研究, 表面, Vol.45, No.10, 357-371, 2007年10月.
石田 竜弘 : 腫瘍血管の構造変化がナノ粒子抗がん剤の効果を変化させる, ファルマシア, Vol.44, No.2, 168-169, 2008年2月.
石田 竜弘, 際田 弘志 : ポリエチレングリコール修飾リポソーム投与時に生ずるaccelerated blood clearance (ABC)現象, 薬学雑誌, Vol.128, No.2, 233-243, 2008年2月.
Taisuke Matsuo, Naoshi Yamazaki, Tatsuhiro Ishida, Hiroshi Kiwada, Yasuo Shinohara and Masatoshi Kataoka : Mutant coat proteins of Pf3 bacteriophage as models of membrane proteins and their interactions with lipid bilayer membrane, Pre-Satellite Meeting of the 3rd Pharmaceutical Sciences World Congress (PSWC 2007) for and by Ph.D. students and postdoctoral fellows, Amsterdam, Apr. 2007.
Tatsuhiro Ishida, Tatsuaki Tagami, Barichello M. Jose, Kiyomi Hirose, Naoshi Yamazaki, Tomohiro Asai, Naoto Oku and Hiroshi Kiwada : Argonaute2 (Ago2) gene silencing by liposomal transfection with siRNA for Ago2 induces apoptosis on HT1080 cells and HUVECs., American Society of Gene Therapy's 10th annual Meeting, Seattle USA, May 2007.
Barichello M. Jose, Tatsuhiro Ishida, Soares A. L. Luiz, Shinji Kizuki, Tatsuaki Tagami, Kiyomi Hirose, Hideo Kobayashi, Kouichi Hashimoto, Hiroshi Kikuchi and Hiroshi Kiwada : Agitation during siRNA-cationic liposomes (CL) complex formation is a key step to improve in vitro RNA interference by lipofection., American Society of Gene Therapy's 10th annual Meeting, Seattle USA, May 2007.
T Asai, Y Suzuki, S Matsushita, J Yokota, Tatsuhiro Ishida, Hiroshi Kiwada and N Oku : Development of antineovascular RNAi cancer therapy targeting to Argonaute 2., American Society of Gene Therapy's 10th annual Meeting, Seattle USA, May 2007.
H Miyauchi, K Ichikawa, T Urakami, S Yonezawa, K Shimizu, Tatsuhiro Ishida, Hiroshi Kiwada, T Asai and N Oku : Antigen-conjugated liposomes enhanced hyposensitization immune therapy with extra-low doses., 34th Annual Meeting & Exposition of the Controlled Release Society, USA, Jul. 2007.
Taisuke Matsuo, Naoshi Yamazaki, Tatsuhiro Ishida, Hiroshi Kiwada, Yasuo Shinohara and Masatoshi Kataoka : Design, preparation and directional insertion of peptides into lipid bilayer membrane and heir application for the preparation of liposome of which surface could be coated by externally added antibody, International symposium on system cell engineering by multi-scale manipulation, Nagoya, Nov. 2007.
石田 竜弘 : ポリマー修飾ナノ微粒子の組織・細胞反応性とバイオ応用に関する研究, 花王芸術・科学財団第9回助成研究発表会, 2007年5月.
石田 竜弘 : PEG修飾リポソーム投与時に惹起される免疫反応に関する研究, 日本薬剤学会第22年会,奨励賞受賞講演, 2007年5月.
石田 竜弘 : リポソームDDSによる体内動態制御に基づく創薬・育薬の試み, Bio Japan2007, World Buisiness Forum, 2007年9月.
東 満美, 日野出 晴美, 柏田 良樹, 吉田 昌裕, 山﨑 尚志, 土屋 浩一郎, 山内 あい子, 柴田 洋文, 新垣 尚捷, 滝口 祥令, 荒木 勉, 吉村 好之, 姫田 敏樹, 石田 竜弘, 辻 大輔, 木原 勝 : 徳島大学薬学部OSCEトライアル実施体制の確立と検証, 第17回 日本医療薬学会年会, 2007年9月.
石田 竜弘 : 抗がん剤含有新生血管標的ナノキャリアの開発とその腫瘍休眠療法への展開, とくしま健康・医療クラスター創成フォーラム2008, 2008年1月.
石田 竜弘 : リポソームを基盤としたDDSの開発研究∼効果増強と安全性の観点から∼, 第三回DDS熊本シンポジウム, 2008年2月.
松尾 泰佑, 山﨑 尚志, 新山 加菜美, 山本 武範, 石田 竜弘, 際田 弘志, 片岡 正俊, 篠原 康雄 : タグを付加したPf3 coat protein変異体の調製およびリポソームとの相互作用の解析, 2008年3月.