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Research

Field of Study

Biochemistry

Subject of Study

プロセシングプロテアーゼの構造と生理機能, ペプチドホルモンの生合成調節機構, 血清タンパクの合成と分泌 (enzyme, protease, gene, peptide hormone, nerves)

Book / Paper

Book:

1. 石田 寿昌, 石野 良純, Hideaki Nagamune, 岡本 敬の介, 梶本 和昭, 加藤 郁之進, 金保 安則, 河野 通明, 小池 晴彦, 佐藤 真悟, 鮫島 勇次, Yasuo Shinohara, Akihiko Tsuji, Hiroshi Terada, 富田 基郎, 友尾 幸司, 野沢 義則, 野元 裕, 濱崎 直孝, 日野 真美, 平松 宏一, 藤井 敏, 藤井 儀夫, 洪 英満, Yoshiko Matsuda, 森 秀治, 山崎 尚志, 山本 格 and 若原 章男 :
タンパク質と核酸の分離精製,
株式会社 廣川書店, Tokyo, Jun. 2001.
2. Yoshiko Matsuda, Akihiko Tsuji and Hideaki Nagamune :
タンパク質と核酸の分離精製·基礎と実験(共著),
株式会社 廣川書店, Tokyo, Jan. 2001.
3. Hideaki Nagamune, Kazuaki Muramatsu, Masakatsu Higashine, Tetsuya Akamatsu, Yasuhiro Tamai, Yasuo Yonetomi, Akihiko Tsuji, Keisuke Izumi, Takemasa Sakaguchi, Tetsuya Yoshida and Yoshiko Matsuda :
Cyclic AMP-inducible procalcitonin processing in thyroidal parafollicular cells is regulated by the Kexin family protease, PC1.,
IOS Press, Amsterdam, Mar. 1997.
4. Yoshiko Matsuda :
プロテアーゼとそのインヒビター,
MEDICAL VIEW CO., LTD., Tokyo, Jan. 1992.
5. Akihiko Tsuji and Yoshiko Matsuda :
膜酵素 基礎と実験II,
株式会社 廣川書店, 東京都, May 1990.
6. Akihiko Tsuji and Yoshiko Matsuda :
膜酵素 基礎と実験I,
株式会社 廣川書店, 東京都, May 1990.
7. 阿久津 秀雄, 伊藤 明夫, Hideaki Nagamune, 久野 健夫, 小南 英紀, 田代 裕, 田中 啓二, Akihiko Tsuji, Hiroshi Terada, 中野 明彦, 中安 博司, 能見 貴人, 日野 幸伸, 二井 将光, 前田 正知, Yoshiko Matsuda, 三原 勝芳, 克子 山下 and 山本 章嗣 :
膜酵素I –基礎と実験-,膜酵素II –基礎と実験-,
株式会社 廣川書店, Tokyo, May 1990.
8. Akihiko Tsuji and Yoshiko Matsuda :
電気泳動法 基礎と実験,
株式会社 廣川書店, 東京都, Apr. 1989.
9. 市川 哲生, Fusao Ota, Hideaki Nagamune, 久保 兼信, 桜林 郁之介, 佐藤 真悟, Yasuo Shinohara, 高木 俊夫, 竹尾 和典, 田中 経彦, Akihiko Tsuji, Hiroshi Terada, 中尾 真, 中村 和行, 藤田 清貴, Yoshiko Matsuda and 真鍋 敬 :
電気泳動法 –基礎と実験-,
株式会社 廣川書店, Tokyo, Apr. 1989.
10. Nobuhiko Katunuma, Yoshiko Matsuda, Akihiko Tsuji and Tsutomu Miura :
Release and Modulation of Membrane-bound γ-Glutamyltranspeptidase by Limited Proteolysis,
Springer-Verlag, Berlin, Jan. 1981.

Academic Paper (Judged Full Paper):

1. Keizo Yuasa, Tetsuya Masuda, Chihiro Yoshikawa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
Subtilisin-like Proprotein Convertase PACE4 is Required for Skeletal Muscle Differentiation,
The Journal of Biochemistry, Vol.146, No.3, 407-415, 2009.
(DOI: 10.1093/jb/mvp090,   PubMed: 19520771)
2. Takuya Yanagino, Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
Transcriptional Regulation of Fibrillin-2 Gene by E2F Family Members in Chondrocyte Differentiation,
Journal of Cellular Biochemistry, Vol.106, No.4, 580-588, 2009.
(DOI: 10.1002/jcb.22029,   PubMed: 19142862)
3. Keizo Yuasa, Kaori Suzue, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
Transcriptional regulation of subtilisin-like proprotein convertase PACE4 by E2F: Possible role of E2F-mediated upregulation of PACE4 in tumor progression,
Gene, Vol.402, No.1-2, 103-110, 2007.
(DOI: 10.1016/j.gene.2007.07.028,   PubMed: 17825503)
4. Akihiko Tsuji, Hiroki Kanie, Hirotaka Makise, Keizo Yuasa, Masami Nagahama and Yoshiko Matsuda :
Engineering of α1-antitrypsin cariants selective for subtilisin-like proprotein convertases PACE4 and PC6: Importance of the P2' residue in stable complex formation of the serpin with proprotein convertase,
Protein Engineering, Design & Selection, Vol.20, No.4, 163-170, 2007.
(DOI: 10.1093/protein/gzm007,   PubMed: 17351018)
5. Akihiko Tsuji, Yayoi Kikuchi, Yukimi Sato, Shizuyo Koide, Keizo Yuasa, Masami Nagahama and Yoshiko Matsuda :
A proteomic approach reveals transient association of reticulocalbin-3, a novel member of the CREC family, with the precursor of subtilisin-like proprotein convertase, PACE4,
The Biochemical Journal, Vol.396, No.1, 51-59, 2006.
(DOI: 10.1042/BJ20051524,   PubMed: 16433634)
6. Akihiko Tsuji, Tadashi Yoshimoto, Keizo Yuasa and Yoshiko Matsuda :
Pratamine: a unique and patent inhibitor of oligopeptidase B,
Journal of Peptide Science, Vol.12, No.1, 65-71, 2006.
(DOI: 10.1002/psc.683,   PubMed: 15948139)
7. Akihiko Tsuji, Keizo Yuasa and Yoshiko Matsuda :
Identification of Oligopeptidase B in Higher Plants. Purification and Characterization of Oligopeptidase B from Quiescent Wheat Embryo, Triticum aestivum,
The Journal of Biochemistry, Vol.136, No.5, 673-681, 2004.
(DOI: 10.1093/jb/mvh163,   PubMed: 15632308)
8. Akihiko Tsuji, Manami Tsuji, Hirimiti Takami, Shingo Nakamura and Yoshiko Matsuda :
Molecular cloning and expression analysis of novel wheat cysteine protease,
Biochimica et Biophysica Acta (BBA) - General Subjects, Vol.1670, No.1, 84-89, 2004.
(DOI: 10.1016/j.bbagen.2003.10.009,   PubMed: 14729145)
9. Shizuyo Koide, Ichiro Yoshida, Akihiko Tsuji and Yoshiko Matsuda :
The expression of proprotein convertase PACE4 is highly regulated by Hash-2 in placenta: Possible role of placenta-specific basic helix-loop-helix transcription factor, human Achaete-Scute homologue-2,
The Journal of Biochemistry, Vol.134, No.3, 433-440, 2003.
(DOI: 10.1093/jb/mvg161,   PubMed: 14561729)
10. Akihiko Tsuji, Kensuke Sakurai, Emi Kiyokage, Takahito Yamazaki, Shizuyo Koide, Kazunori Toida, Kazunori Ishimura and Yoshiko Matsuda :
Secretory proprotein convertases PACE4 and PC6A are heparin-binding proteins which are localized in the extracellular matrix. Potential role of PACE4 in the activation of proproteins in the extracellular matrix,
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Vol.1645, No.1, 95-104, 2003.
(DOI: 10.1016/S1570-9639(02)00532-0,   PubMed: 12535616)
11. Miwa Bando, Atsushi Matsuoka, Akihiko Tsuji and Yoshiko Matsuda :
The proprotein convertase PACE4 is upregulated by PDGF-BB in megakaryocytes: gene expression of PACE4 and furin is regulated differently in Dami cells,
The Journal of Biochemistry, Vol.132, No.1, 127-134, 2002.
(PubMed: 12097169,   CiNii: 1390282679908516864,   Elsevier: Scopus)
12. Akihiko Tsuji, Takayuki Ikoma, Emi Hashimoto and Yoshiko Matsuda :
Development of selectivity of α1-antitrypsin variant by mutagenesis in its reactive site loop against proprotein convertase. A crutial role of the P4 arginine in PACE4 inhibition,
Protein Engineering, Vol.15, No.2, 123-130, 2002.
(DOI: 10.1093/protein/15.2.123,   PubMed: 11917148)
13. Takazumi Taniguchi, Rieko Kuroda, Kensuke Sakurai, Masami Nagahama, Ikuo Wada, Akihiko Tsuji and Yoshiko Matsuda :
A Critical Role for the Carboxy Terminal Region of the Proprotein Convertase, PACE4A, in the Regulation of Its Autocatalytic Activation Coupled with Secretion,
Biochemical and Biophysical Research Communications, Vol.290, No.2, 878-884, 2002.
(DOI: 10.1006/bbrc.2001.6282,   PubMed: 11785985)
14. Ichiro Yoshida, Shizuyo Koide, Shin-ichi Hasegawa, Akira Nakagawara, Akihiko Tsuji and Yoshiko Matsuda :
Proprotein convertase PACE4 is down-regulated by the basic helix-loop-helix transcription factor hASH-1 and MASH-1,
The Biochemical Journal, Vol.360, No.3, 683-689, 2001.
(DOI: 10.1042/0264-6021:3600683,   CiNii: 1573950399804603392,   Elsevier: Scopus)
15. Tetsuya Akamatsu, Yoshiko Matsuda, Keiko Tsumura, Jun Tada, Most Nahid Parvin, Wei Wei, Norio Kanamori and Kazuo Hosoi :
Highly regulated expression of subtilisin-like proprotein convertase PACE4 (SPC4) during dentinogenesis.,
Biochemical and Biophysical Research Communications, Vol.272, No.2, 410-415, 2000.
(DOI: 10.1006/bbrc.2000.2752,   PubMed: 10833428,   Elsevier: Scopus)
16. Tetsuya Akamatsu, Yoshiko Matsuda, Keiko Tsumura, Jun Tada, Most Nahid Parvin, Norio Kanamori and Kazuo Hosoi :
Subtilisin-like proprotein convertase PACE4 (SPC4) is a candidate processing enzyme of bone morphogenetic proteins during tooth formation,
Developmental Dynamics, Vol.216, No.4/5, 481-488, 1999.
17. Kenji Mori, Akiyoshi Imamaki, Kaya Nagata, Yasuo Yonetomi, Ryoko Kiyokage-Yoshimoto, John T Martin, Matthew T Gillespie, Masami Nagahama, Akihiko Tsuji and Yoshiko Matsuda :
Subtilisin-Like Proprotein Convertase, PACE4 and PC8, as Well as Furin, are Endogenous Proalbumin Convertases in HepG2 Cells,
The Journal of Biochemistry, Vol.125, No.3, 627-633, 1999.
18. Akihiko Tsuji, Emi Hashimoto, Takayuki Ikoma, Takazumi Taniguchi, Kenji Mori, Masami Nagahama and Yoshiko Matsuda :
Inactivation of Proprotein Convertase, PACE4 by α1-Antitrypsin Portland (α1-PDX) which is a Blocker of Proteolytic Activation of Bone Morphogenetic Protein during Embryogenesis.,
The Journal of Biochemistry, Vol.126, No.3, 591-603, 1999.
19. Akihiko Tsuji, Shigeru Yoshida, Shinichi Hasegawa, Miwa Bando, Ichiro Yoshida, Shizuyo Koide, Kenji Mori and Yoshiko Matsuda :
Human Subtilisin-Like Proprotein Convertase, PACE4 (SPC4) Gene Expression Is Highly Regulated through E-Box Elements in HepG2 and GH4C1 Cells,
The Journal of Biochemistry, Vol.126, No.3, 494-502, 1999.
20. Masami Nagahama, Takazumi Taniguchi, Emi Hashimoto, Akiyoshi Imamaki, Kenji Mori, Akihiko Tsuji and Yoshiko Matsuda :
Biosynthetic processing and quoternary interactions of proprotein convertase SPC4 (PACE4).,
FEBS Letters, Vol.434, No.1, 155-159, 1998.
21. Masami Nagahama, Takazumi Taniguchi, Emi Hashimoto, Akiyoshi Imamaki, Kenji Mori, Akihiko Tsuji and Yoshiko Matsuda :
Biosynthetic processing and quaternary interactions of proprotein convertase SPC4 (PACE4).,
FEBS Letter, Vol.434, 155-159, 1998.
22. Hideaki Nagamune, Hiroki Kourai, Ayako Katsuura, Yasuki Taoka, Kenzo Fushitani, Robert A. Whiley, Kikuji Yamashita, Akihiko Tsuji, Yoshiko Matsuda, Hiroki Kourai and Seiichiro Kitamura :
Intermedilysin A cytolytic toxin specific for human cells of a Streptococcus intermedius isolated from human liver abscess in "Streptococci and The Host",
Advances in Experimental Medicine and Biology, Vol.418, 773-775, 1997.
23. Akihiko Tsuji, Chiemi Hine, Yasuhiro Tamai, Kayoko Yonemoto, Kazushige Mori, Shigeru Yoshida, Miwa Bando, Eri Sakai, Kenji Mori, Tetsuya Akamatsu and Yoshiko Matsuda :
Genomic organization and alternative splicing of human PACE4 (SPC4), Kexin-like processing endoprotease.,
The Journal of Biochemistry, Vol.122, No.2, 438-452, 1997.
24. Tetsuya Akamatsu, Shigeo Daikoku, Hideaki Nagamune, Shigeru Yoshida, Kenji Mori, Akihiko Tsuji and Yoshiko Matsuda :
Developmental expression of a novel Kexin family protease, PACE4E, in the rat olfactory system.,
Histochemistry and Cell Biology, Vol.108, No.2, 95-103, 1997.
25. Kenji Mori, Sachiko Kii, Akihiko Tsuji, Masami Nagahama, Akiyoshi Imamaki, Keiko Hayashi, Tetsuya Akamatsu, Hideaki Nagamune and Yoshiko Matsuda :
A Novel Human PACE4 Isoform, PACE4E Is an Active Processing Protease Containing a Hydrophobic Cluster at the Carboxy Terminus,
The Journal of Biochemistry, Vol.121, No.5, 941-948, 1997.
26. Haruyuki Nakayama, Takemi Kinouchi, Keiko Kataoka, Shigeru Akimoto, Yoshiko Matsuda and Yoshinari Ohnishi :
Intestinal anaerobic bacteria hydrolyse sorivudine, producing the high blood concentration of 5-(E)-(2-bromovinyl)uracil that increases the level and toxicity of 5-fluorouracil.,
Pharmacogenetics, Vol.7, No.1, 35-43, 1997.
(PubMed: 9110360,   CiNii: 1570854175671010176)
27. Hideaki Nagamune, Kazuaki Muramatsu, Masakatsu Higashine, Tetsuya Akamatsu, Yasuhiro Tamai, Yasuo Yonetomi, Akihiko Tsuji, Keisuke Izumi, Takemasa Sakaguchi, Tetsuya Yoshida and Yoshiko Matsuda :
Cyclic AMP-inducible procalcitonin processing in thyroidal parafollicular cells is regulated by the kexin family protease, PC1,
Biomedical and Health Research, Vol.15, 22-33, 1997.
28. Hideaki Nagamune, Chikako Ohnishi, Ayako Katsuura, Kenzo Fushitani, Robert A. Whiley, Akihiko Tsuji and Yoshiko Matsuda :
Intermedilysin, a novel cytotoxin specific for human cells, secreted by Streptococcus intermedius UNS46 isolated from a human liver abscess,
Infection and Immunity, Vol.64, No.8, 3093-3100, 1996.
29. Akihiko Tsuji, Keisuke Edazawa, Koji Sakiyama, Kaya Nagata, Yuka Sasaki, Hideaki Nagamune and Yoshiko Matsuda :
Purification and characterization of a novel serine proteinase from the microsomal fraction of bovine pancreas.,
The Journal of Biochemistry, Vol.119, No.1, 100-105, 1996.
30. Akihiko Tsuji, Hideaki Nagamune, Tetsuya Akamatsu, Chiemi Hine, Kazuaki Muramatsu, Kenji Mori, Yasuhiro Tamai, Kayoko Yonemoto and Yoshiko Matsuda :
Novel members of mammalian kexin family proteases, PACE4C, PACE4D, PC7A and PC7B.,
Intracellular Protein Catabolism, Vol.389, 63-71, 1996.
31. Hideaki Nagamune, Kazuaki Muramatsu, Tetsuya Akamatsu, Yasuhiro Tamai, Keisuke Izumi, Akihiko Tsuji and Yoshiko Matsuda :
Distribution of the kexin family proteases in pancreatic islets., --- PACE4C is specifically expressed in B cells of pancreatic islets ---,
Endocrinology, Vol.136, No.1, 357-360, 1995.
32. Akihiko Tsuji, Chiemi Hine, Kenji Mori, Yasuhiro Tamai, Kazuya Higashine, Hideaki Nagamune and Yoshiko Matsuda :
A Novel Member, PC7, of The Mammalian Kexin-Like Protease Family, --- Homology to PACE4A, Its Brainspecific Expression and Identification of Isoforms ---,
Biochemical and Biophysical Research Communications, Vol.202, No.3, 1452-1459, 1994.
33. Akihiko Tsuji, Kenji Mori, Chiemi Hine, Yasuhiro Tamai, Hideaki Nagamune and Yoshiko Matsuda :
The tissue distribution of mRNAs for the PACE4 isoforms, kexin-like processing protease: PACE4C and PACE4D mRNAs are major transcripts among PACE4 isoforms,
Biochemical and Biophysical Research Communications, Vol.202, No.3, 1215-1221, 1994.
34. Akihiko Tsuji, Ryoichi Oda, Kohji Sakiyama, Hideaki Nagamune, Kouji Itou, Ryoichi Kase, Hitoshi Sakuraba, Yoshiyuki Suzuki and Yoshiko Matsuda :
Lysosomal enzyme replacement using α2-macroglobulin as a transport vehicle,
The Journal of Biochemistry, Vol.115, No.5, 937-944, 1994.
35. Akihiko Tsuji, Kazuya Higashine, Chiemi Hine, Kenji Mori, Yasuhiro Tamai, Hideaki Nagamune and Yoshiko Matsuda :
Identification of Novel cDNAs Encording Human Kexin-like Protease, PACE4 Isoforms,
Biochemical and Biophysical Research Communications, Vol.200, No.2, 943-950, 1994.
36. Akihiko Tsuji, Tetsuya Akamatsu, Hideaki Nagamune and Yoshiko Matsuda :
Identification of targeting proteinase for rat α1-macroglobulin in vivo., --- Mast-cell tryptase is a major component of the α1-macroglobulin-proteinase complex endocytosed into rat liver lysosomes. ---,
The Biochemical Journal, Vol.298, No.1, 79-85, 1994.
37. Katsuko Yamashita, Yoko Tachibana, Akira Hitoi, Yoshiko Matsuda, Akihiko Tsuji, Nobuhiko Katunuma and Akira Kobata :
Differences in the sugar chains of two subunits and isozymic forms of rat kidney γ-glutamyltranspeptidase,
Archives of Biochemistry and Biophysics, Vol.227, No.1, 225-232, 1983.
38. Katsuko Yamashita, Akira Hitoi, Yoshiko Matsuda, Akihiko Tsuji, Nobuhiko Katunuma and Akira Kobata :
Structural studies of the carbohydrate moieties of rat kidney γ-glutamyltranspeptidase,
The Journal of Biological Chemistry, Vol.258, No.2, 1098-1107, 1983.
39. Yoshiko Matsuda, Akihiko Tsuji and Nobuhiko Katunuma :
Studies on the structure of γ-glutamyltranspeptidase. III. Evidence that the amino terminus of the heavy subunit is membrane binding segment,
The Journal of Biochemistry, Vol.93, No.5, 1427-1433, 1983.
40. Tsutomu Miura, Yoshiko Matsuda, Akihiko Tsuji and Nobuhiko Katunuma :
Immunological cross reactivity of γ-glutamyltranspeptidase from human and rat kidney, liver and bile,
The Journal of Biochemistry, Vol.89, No.1, 217-222, 1981.
41. Yoshiko Matsuda, Akihiko Tsuji and Nobuhiko Katunuma :
Studies on the structure of γ-glutamyltranspeptidase. I. Correlation between sialylation and isozymic,
The Journal of Biochemistry, Vol.87, No.No 4, 1243-1248, 1980.
42. Akihiko Tsuji, Yoshiko Matsuda and Nobuhiko Katunuma :
Studies on the structure of g-glutamyltranspeptidase. II. Location of the segment anchoring γ-glutamyltranspeptidase to the membrane,
The Journal of Biochemistry, Vol.87, No.No 6, 1567-1571, 1980.
43. Akihiko Tsuji, Yoshiko Matsuda and Nobuhiko Katunuma :
Characterization of human serum γ-glutamyltranspeptidase,
Clinica Chimica Acta, Vol.104, No.3, 361-366, 1980.
44. Akihiko Tsuji, Yoshiko Matsuda and Nobuhiko Katunuma :
Purification and characterization of γ-glutamyltranspeptidase from human bile,
Biomedical Research, Vol.1, 410-416, 1980.
45. Yoshiko Matsuda, Akihiko Tsuji, Nobuhiko Katunuma, Masanori Hayashi and Yoshiyata Takahashi :
Studies on liver argininosuccinate synthetase in a patient with citrullinemia and in normal subjects,
The Journal of Biochemistry, Vol.85, No.No 1, 192-195, 1979.
46. 上田 敦子, 大西 悦子, Shiro Saito, Yoshiko Matsuda, Akihiko Tsuji and 勝沼 信彦 :
血清Ornithin carbamyltransferaseの脂肪肝に対する診断的意義,
臨床化学, Vol.6, No.2, 125-130, 1978.

Academic Paper (Unrefereed Paper):

1. Yoshiko Matsuda, Hitoshi Hori, Akihiko Tsuji, Hideko Nagasawa, Yoshihiro Uto, Rieko Kuroda, 葛西 宗江, Miwa Bando, 吉田 一郎, 上田 祐司 and サハルディン B. モハマッド :
新医薬品の開発をめざした脳神経特異的発現遺伝子産物のプロテオミクス解析,
Bulletin of Faculty of Engineering, The University of Tokushima, Vol.46, 49-56, 2001.
2. Masami Nagahama, Ichiro Yoshida, Keiichi Uyemura, Akihiko Tsuji and Yoshiko Matsuda :
Proteolytic Cleavage of the Neural Cell Adhesion Molecule L1 by Subtilisin-Like Proprotein Convertases,
Keio University Symposia for Life Science and Medicine, Vol.2, 261-266, 1999.

Review, Commentary:

1. 森 健二, Akihiko Tsuji and Yoshiko Matsuda :
先天性異常アルブミン症,無アルブミン血症,先天代謝異常症候群-遺伝子解析の進歩と成果-,
Nihon Rinsho. Japanese Journal of Clinical Medicine, Vol.19, No.5, 657-670, May 1998.
2. 森 健二, Akihiko Tsuji and Yoshiko Matsuda :
先天性異常アルブミン症,無アルブミン血症,
先天代謝異常症候群ー遺伝子解析の進歩と成果, Vol.19, 123-127, 1998.
3. Yoshiko Matsuda and Akihiko Tsuji :
前駆体蛋白質の活性化とケキシンファミリー,プロセシングプロテアーゼ,
蛋白質 核酸 酵素, Vol.42, No.14, 2355-2361, Aug. 1997.
4. Yoshiko Matsuda, Akihiko Tsuji, Hideaki Nagamune, Tetsuya Akamatsu, Chiemi Hine, Kazuaki Muramatsu, Kenji Mori, Yasuhiro Tamai and Kayoko Yonemoto :
Novel members of mammalian Kexin family proteases, PACE4C, PACE4D, PC7A and PC7B.,
Advances in Experimental Medicine and Biology, Vol.389, 63-71, Sep. 1996.
5. Yoshiko Matsuda, Akihiko Tsuji, Hideaki Nagamune, Tetsuya Akamatsu, Chiemi Hine, Kazuaki Muramatsu, Kenji Mori, Yasuhiro Tamai and Kayoko Yonemoto :
Novel members of mammalian Kexin family proteases, PACE4C, PACE4D, PC7A and PC7B,
Intracellular protein catabolism, Vol.389, No.7, 63-71, Jan. 1996.
6. Akihiko Tsuji, 窪野 慎一, Yuka Sasaki, Yoshiko Matsuda, 中山 久幸 and 寺山 日出男 :
ピロリドンカルボン酸ソーダによるビオプラーゼの安定化とレンズ洗浄剤としての応用,
日本コンタクトレンズ学会誌, Vol.38, 232-236, Jan. 1996.
7. Yoshiko Matsuda :
ケキシン様プロテアーゼファミリー,
生体の科学, Vol.46, No.5, 497-498, Oct. 1995.
8. Yoshiko Matsuda :
Kexin型プロテアーゼ,
バイオサイエンスとインダストリー, Vol.53, No.12, 1045-1046, Jan. 1995.
9. Yoshiko Matsuda, Akihiko Tsuji and Nobuhiko Katunuma :
Quantitative abnormality of argininosuccinate synthetase in a patient with citrullinemia,
Advancesin Experimental Medicine and Biology, Urea Cycle Disease, Vol.153, 77-82, 1984.
10. Yoshiko Matsuda, Akihiko Tsuji, 久野 健夫 and 勝沼 信彦 :
γ-GTPの生体内運命,血清,胆汁への逸脱機構,
日本臨床化学会記録, Vol.23, 12-13, 1983.
11. 林 真功, 高橋 善弥太, Yoshiko Matsuda, Akihiko Tsuji and 勝沼 信彦 :
アルギニノコハク酸合成酵素の質的異常に起因するシトルリン血症,
Metabolism and Disease, Vol.15, No.No 9, 1253-1257, 1978.

Proceeding of International Conference:

1. Keizo Yuasa, Kaori Suzue, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
Subtilisin-like proprotein convertase PACE4 is transcriptionally regulated by E2F/Rb,
International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors. Satellite meeting of the 20th IUBMB International congress and 11th FAOBMB Congress, Hyogo, Jun. 2006.
2. Tetsuya Masuda, Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
Transcriptional Activation of processing protease PACE4 during myogenic differentiation.,
International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors. Satellite meeting of the 20th IUBMB International congress and 11th FAOBMB Congress, Hyogo, Jun. 2006.
3. Takuya Yanagino, Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
Transcriptional Regulation of Fibrillin-2 Gene during Chondrogenrsis,
20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress, Kyoto, Jun. 2006.
4. Akihiko Tsuji, Keizo Yuasa, Masami Nagahama and Yoshiko Matsuda :
Role of PACE4 and furin in cell differentiation,
International Conference on Serine-Carboxyl Peptidases 2005, Kyoto, Nov. 2005.
5. Akihiko Tsuji, Yayoi Kikuchi and Yoshiko Matsuda :
Reticulocalbin-3: A novel protein which regulates biosynthesis of subtilisin-like proprotein convertase,
The 1st Pacific-Rim International Conference on Protein Science, 129, Yokohama, Apr. 2004.
6. Go Futamatsu, Tomonori Shimada, Akihiko Tsuji and Yoshiko Matsuda :
Functional analysis of the processing protease PACE4 during chondrogenic differentiation of ATDC5 cells,
International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors., 36, Hyogo, Nov. 2003.
7. Akihiko Tsuji, Shizuyo Koide, Keizo Yuasa and Yoshiko Matsuda :
Involvement of PACE4 in activation of TGF beta-related factors in the ECM,
International Symposium on Medical and Biological Perspectives in Proteases and Their Inhibitors., 20, Hyogo, Nov. 2003.
8. Akihiko Tsuji, Yayoi Kikuchi, Yukimi Sato, Shizuyo Koide and Yoshiko Matsuda :
Reticulocalbin-like protein (RCN3): A novel protein which regulates biosynthesis of subtilisin-like proprotein convertase (SPC),
3rd General Meeting of the International Proteolysis Society, 187, Nagoya, Nov. 2003.
9. Akihiko Tsuji and Yoshiko Matsuda :
Enhancement of selectivity of α1-antitrypsin variant against subtilisin-like proprotein convertase by mutagenesis in RSL and application for functional analysis,
Second General Meeting of International Proteolysis Society, 59, Germany, Oct. 2001.
10. Akihiko Tsuji and Yoshiko Matsuda :
Unique Mechanism Governing Cell-Specific Expression and Biosynthetic Processing of PACE4,
International Proteolysis Society First Gemeral Meeting, 38, Michigan, USA, Sep. 1999.
11. Yoshiko Matsuda :
Regulation of subtilisin like proprotein convertase PACE4 gene expression and post translational activation,
6th International Symposium on Proteinase Inhibitors and Biological Control, 25, Slovenia, Jun. 1999.
12. Akihiko Tsuji and Yoshiko Matsuda :
Regulation of PACE4 expression under dynamic bHLH network and its physiological importance,
6th CGGH Symposium "Roles of Proteolysis in Health and Disease", 3, Tokushima, May 1999.
13. Kenji Mori, Akihiko Tsuji and Yoshiko Matsuda :
Subtilisin-like Proprotein Convertase, PACE4, participates in the Processing of Plasma protein precursors in human hepatoma HepG2 cells,
6th CGGH Symposium "Roles of Proteolysis in Health and Disease", 80, Tokushima, May 1999.
14. Shin-ichi Hasegawa, Ichiro Yoshida, Shizuyo Koide, Akihiko Tsuji and Yoshiko Matsuda :
Transcriptional Regulation of the Human PACE4 Gene Expression in HepG2 and GH4C1 cells,
6th CGGH Symposium "Roles of Proteolysis in Health and Disease", 83, Tokushima, May 1999.
15. Emi Hashimoto, Takayuki Ikoma, Akihiko Tsuji and Yoshiko Matsuda :
Proprotein Convertase PACE4 is inhibited by α1-Antitrypsin cariant Portland,
6th CGGH Symposium "Roles of Proteolysis in Health and Disease", 82, Tokushima, May 1999.
16. Miwa Bando, Atsushi Matsuoka, Akihiko Tsuji and Yoshiko Matsuda :
Physiological Function of PACE4 on megakaryoblastic differentiation,
6th CGGH Symposium "Roles of Proteolysis in Health and Disease", 84, Tokushima, May 1999.
17. Ichiro Yoshida, Shizuyo Koide, Akira Nakagawara, Akihiko Tsuji and Yoshiko Matsuda :
Regulation of PACE4 Expression by bHLH factor in neuroblastoma cells,
6th CGGH Symposium "Roles of Proteolysis in Health and Disease", 85, Tokushima, May 1999.
18. Hideaki Nagamune, Chikako Ohnishi, Ayako Katsuura, Yasunori Taoka, Kenzo Fushitani, Robert A. Whiley, Kikuji Yamashita, Akihiko Tsuji, Yoshiko Matsuda, Hiroki Kourai and Seiichiro Kitamura :
Intermedilysin A cytolytic toxin specific for human cells of a Streptococcus intermedius isolated from human liver abscess,
XIII Lancefield International Symposium on Streptococci and Streptococcal Diseases; In "Streptococci and The Host"(T. Horaud, A. Bouvet, R. Leclercq, H. de Montclos, M. Sicard, eds.): Advances in Experimental Medicine and Biology, Vol.418, 773-775, Paris, Sep. 1997.
19. Kenji Mori, 今牧 明義, Tetsuya Akamatsu, Akihiko Tsuji, Masami Nagahama and Yoshiko Matsuda :
A novel human PACE4 isoform, PACE4E, is an active protease containing a hydrophobic cluster at the carboxy terminus,
17th International Congress of Biochemistry and Molecular Biology, San Francisco, Aug. 1997.
20. Akihiko Tsuji, Chiemi Hine, Shigeru Yoshida, Miwa Bando, Kenji Mori, Tetsuya Akamatsu and Yoshiko Matsuda :
Gene organization and Alternative Splicing of Human PACE4, Subtilisin-Like Proprotein Convertase,
17th International Congress of Biochemistry and Molecular Biology, FASEB.J., Vol.11, No.9, 1224, San Francisco, Aug. 1997.
21. Hideaki Nagamune, Kazuaki Muramatsu, Masakatsu Higashine, Tetsuya Akamatsu, Yasuhiro Tamai, Yasuo Yonetomi, Akihiko Tsuji, Keisuke Izumi, Takemasa Sakaguchi, Tetsuya Yoshida and Yoshiko Matsuda :
Cyclic AMP-inducible procalcitonin processing in thyroidal parafollicular cells is regulated by the Kexin family protease, PC1.,
International Symposium on Medical Aspects of Protease Inhibitors; In "Medical Aspects of Proteases and Protease Inhibitors": Biomedical and Health Research, Vol.15, 22-33, Amsterdam, May 1997.
22. Tetsuya Akamatsu, 吉田 茂, 大黒 成夫, Hideaki Nagamune, 長濱 正巳, Akihiko Tsuji and Yoshiko Matsuda :
Expression of a novel PACE4 isoform, PACE4E, in developmental rat brain,
The 12th International Symposium of Federation of Asian and Oceanian Biochemists and Molecular Biologists, Tokushima, Jun. 1996.

Proceeding of Domestic Conference:

1. 室下 大樹, Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
BMP6の活性化を介したサチライシン様プロプロテインコンベルターゼPACE4による軟骨分化誘導,
第82回日本生化学大会, Oct. 2009.
2. Keizo Yuasa, 泰地 裕美, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
軟骨分化過程におけるサチライシン様プロプロテインコンベルターゼPACE4の機能解析,
第13回病態と治療におけるプロテアーゼとインヒビター学会, Aug. 2008.
3. Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
サチライシン様プロプロテインコンベルターゼPACE4は軟骨分化に必須である,
日本農芸化学会2008年度大会, Mar. 2008.
4. Kazuaki Muramatsu, 関 光太, 鈴木 龍介, 前野 貴則, Akihiko Tsuji and Yoshiko Matsuda :
オステオカルシンの成熟化に関与するプロセシング酵素の解析,
第80回日本生化学会大会, Dec. 2007.
5. 柳野 卓也, Keizo Yuasa, 木村 道江, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
軟骨分化におけるフィブリリン-2の機能解析,
第80回日本生化学会大会, Dec. 2007.
6. Keizo Yuasa, 影山 陽子, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
ズブチリシン様プロプロテイン変換酵素PACE4は軟骨分化に必須である,
第80回日本生化学会大会, Dec. 2007.
7. Keizo Yuasa, 増田 哲也, 吉川 千尋, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
ズブチリシン様プロプロテイン変換酵素PACE4は骨格筋分化に必須である,
第48回日本生化学会中国・四国支部例会, May 2007.
8. 柳野 卓也, Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
Transcriptional Regulation of Fibrilin-2 Gene during Chondrogenesis,
日本分子生物学会2006フォーラム, Dec. 2006.
9. 増田 哲也, Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
Subtilisin-like Proprotein Convertase (SPC)は骨格筋分化制御の重要因子である,
第11回病態と治療におけるプロテアーゼとインヒビター研究会, Aug. 2006.
10. Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
軟骨分化におけるsubtilisin-like proprotein convertase (SPC)の機能解析,
第11回病態と治療におけるプロテアーゼとインヒビター研究会, Aug. 2006.
11. Keizo Yuasa, Yoshiko Matsuda and Akihiko Tsuji :
軟骨分化におけるSubtilisin-like proprotein convertase(SPC)の機能解析,
第28回日本分子生物学会年会ワークショップ, Dec. 2005.
12. Takuya Yanagino, Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
Transcriptional regulation of fibrillin-2 during chondrogenesis,
第78回日本生化学会大会, Oct. 2005.
13. Tetsuya Masuda, Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
Transcriptional activation of proprotein convertase PACE4 during skeletal muscle differentiation,
第78回日本生化学会大会, Oct. 2005.
14. Yayoi Kikuchi, Keizo Yuasa, Masami Nagahama, Yoshiko Matsuda and Akihiko Tsuji :
The role of Reticulocalbin-3 in regulation of PACE4 activation and secretion,
第78回日本生化学会大会, Oct. 2005.
15. Akihiko Tsuji, Keizo Yuasa and Yoshiko Matsuda :
サチライシン様プロプロテインコンベルターゼのユニークな自己活性化制御機構,
第5回日本蛋白質科学会年会ワークショップ9, Jun. 2005.
16. Keizo Yuasa, Akihiko Tsuji and Yoshiko Matsuda :
骨格筋分化におけるプロセシングプロテアーゼPACE4の遺伝子発現調節の解析,
日本農芸化学会2005年度大会, Mar. 2005.
17. Akihiko Tsuji, Keizo Yuasa and Yoshiko Matsuda :
哺乳類ズブチリシン様セリンプロテアーゼの特性,多様性と生理的意義,
日本農芸化学会2005年度大会ワークショップ, Mar. 2005.
18. 鈴江 加織, Keizo Yuasa, Akihiko Tsuji and Yoshiko Matsuda :
E2F1によるPACE4遺伝子発現調節の解析,
第27回日本分子生物学会年会, Dec. 2004.
19. Keizo Yuasa, Kaori Suzue, Akihiko Tsuji and Yoshiko Matsuda :
Transcriptional activation of proprotein convertase PACE4 by E2F1,
第77回日本生化学会大会, Oct. 2004.
20. Akihiko Tsuji, Keizo Yuasa and Yoshiko Matsuda :
Purification and characterization of oligopeptidase B from wheat germ. First identification of oligopeptidase B at the protein level in higer plant,
第77回日本生化学会大会, Oct. 2004.
21. Yoshiko Matsuda, Akihiko Tsuji and Keizo Yuasa :
Subtilisin like proprotein convertase familyの多様性と役割分担:ECM局在PACE4の細胞分化における役割,
第51回マトリックス研究会大会, 20-21, Apr. 2004.
22. 牧瀬 広孝, Akihiko Tsuji and Yoshiko Matsuda :
α1-アンチトリプシン変異体を用いたSPC ファミリー基質特異性の解析,
第26回日本分子生物学会年会, Dec. 2003.
23. Akihiko Tsuji, 菊池 弥生 and Yoshiko Matsuda :
ズブチリシン様プロプロテインコンベルターゼ生合成におけるEF-Hand Ca結合タンパク,Reticulocalbin-like Protein (RLP)の機能同定,
第26回日本分子生物学会, Dec. 2003.
24. Yayoi Kikuchi, Yukimi Sato, Akihiko Tsuji and Yoshiko Matsuda :
Reticulocabin: A novel protein which regulates biosynthesis of subtilisin-like proprotein convertase,
第76回日本生化学会大会, Oct. 2003.
25. Yoshiko Matsuda and Akihiko Tsuji :
A unique 26-kDa cysteine protease induced in wheat embryo during germination,
第76回日本生化学会大会, Oct. 2003.
26. Akihiko Tsuji, Hirotaka Makise and Yoshiko Matsuda :
Antitrypsin mutants: Tool for functional analysis of serine-endopeptidases,
第76回日本生化学会大会, Oct. 2003.
27. Akihiko Tsuji, 佐藤 幸美 and Yoshiko Matsuda :
PACE4生合成におけるレティキュロカビンの機能解析—シャペロンとしての役割—,
第3回日本蛋白質科学会年会, Jun. 2003.
28. 二松 豪, 嶋田 知訓, Akihiko Tsuji and Yoshiko Matsuda :
ATDC5細胞の内軟骨分化過程におけるプロセシングプロテアーゼPACE4の機能解析,
第25回日本分子生物学会年会, Dec. 2002.
29. Akihiko Tsuji, 生駒 貴之, 橋本 英美, 山下 大 and Yoshiko Matsuda :
ズブチリシン様プロプロテインコンベルターゼ(SPC)に特異阻害活性を持つα1-アンチトリプシン改変体の作製と機能解析への応用,
平成14年度日本生物工学会大会, Oct. 2002.
30. 佐藤 幸美, 田頭 和幸, Akihiko Tsuji and Yoshiko Matsuda :
プロテオーム解析によるSPCファミリーの基質タンパクの検索:Ca結合タンパクReticulocabinについて,
第75回日本生化学会大会, Oct. 2002.
31. 田中 幸子, Akihiko Tsuji and Yoshiko Matsuda :
ズブチリシン様プロプロテインコンヴェルターゼ(SPC)に選択的阻害活性を有するα1アンチトリプシン改変体の作成と応用,
第75回日本生化学会大会, Oct. 2002.
32. 高橋 保充, 櫻井 謙介, Akihiko Tsuji and Yoshiko Matsuda :
細胞外マトリックスにおけるズブチリシン様プロセシングプロテアーゼPACE4の役割,
第75回日本生化学会大会, Oct. 2002.
33. 小出 静代, Kazunori Toida, Kazunori Ishimura, Akihiko Tsuji and Yoshiko Matsuda :
胎盤特異的bHLH型転写因子MASH-2によるPACE4の胎盤発生過程における制御,
第75回日本生化学会大会, Oct. 2002.
34. Miwa Bando, 山下 大, Hiroshi Kido, Akihiko Tsuji and Yoshiko Matsuda :
巨核球分化におけるプロセシングプロテアーゼPACE4とfurinの転写調節機構,
Seikagaku, Vol.74, No.8, 1016, Oct. 2002.
35. Akihiko Tsuji, 生駒 貴之, 橋本 英美, 山下 大 and Yoshiko Matsuda :
ズブチリシン様プロプロテインコンベルターゼに選択的阻害作用を有するアンチトリプシン改変体の開発,
第2回日本蛋白質科学会年会, Jun. 2002.
36. 吉田 聡子, Kikuji Yamashita, Akihiko Tsuji, Seiichiro Kitamura and Yoshiko Matsuda :
造血及び間質幹細胞培養の開発,
徳島生物学第110回総会, 110, 2002.
37. 小出 静代, 清蔭 恵美, 藤原 良次, 川並 由季, Akihiko Tsuji and Yoshiko Matsuda :
ヒト胎盤でのPACE4遺伝子発現と生理機能の解析,
第24回日本分子生物学会年会, Dec. 2001.
38. 吉田 一郎, 小出 静代, Kazunori Toida, Kazunori Ishimura, Akihiko Tsuji and Yoshiko Matsuda :
神経特異的bHLH型転写因子Mash-1による前駆体タンパク質活性化酵素PACE4の神経発生過程における制御,
第24回日本分子生物学会年会, Dec. 2001.
39. 嶋田 知訓, Miwa Bando, 開 裕司, 宿南 知佐, Akihiko Tsuji and Yoshiko Matsuda :
ATDC5細胞の軟骨分化過程におけるSPCファミリーの動態,
第74回日本生化学会大会, Oct. 2001.
40. Akihiko Tsuji, 生駒 貴之 and Yoshiko Matsuda :
サブチリシン様プロプロテインコンベルターゼ,PACE4, Furin, PC6に対する選択的阻害作用を持つアンチトリプシン改変体の作成,
第74回日本生化学会大会, Oct. 2001.
41. Miwa Bando, 嶋田 知訓, Akihiko Tsuji and Yoshiko Matsuda :
巨核球分化におけるプロセシングプロテアーゼPACE4の生理機能の解析,
第74回日本生化学会大会, Oct. 2001.
42. 櫻井 謙介, 谷口 孝純, Akihiko Tsuji and Yoshiko Matsuda :
プロセシングプロテアーゼPACE4の活性発現と細胞外での機能の解析,
第53回日本細胞生物学会, Oct. 2000.
43. 櫻井 謙介, 谷口 孝純, 清蔭 恵美, Akihiko Tsuji and Yoshiko Matsuda :
細胞外マトリックスにおけるヒト前駆体タンパク質プロセシングプロテアーゼPACE4の機能解析,
第73回日本生化学会大会, Oct. 2000.
44. 松岡 厚志, Miwa Bando, 平山 幸子, Akihiko Tsuji and Yoshiko Matsuda :
ズブチリシン様前駆体タンパク質プロセシングプロテアーゼPACE4アイソフォーム:PACE4Cの生理的役割,
第73回日本生化学会大会, Oct. 2000.
45. 吉田 一郎, 小出 静代, 中川原 章, Akihiko Tsuji and Yoshiko Matsuda :
神経芽細胞腫におけるbHLH型転写因子hASH-1による前駆体タンパク質活性化酵素PACE4遺伝子の発現制御,
第73回日本生化学会大会, Oct. 2000.
46. Tetsuya Akamatsu, 吉田 茂, Hideaki Nagamune, Akihiko Tsuji and Yoshiko Matsuda :
ラット脳発生過程でのプロセシング酵素PACE4の発現,
日本生化学会第70回大会, Sep. 1997.
47. Tetsuya Akamatsu, 吉田 茂, 大黒 成夫, Hideaki Nagamune, 長濱 正巳, Akihiko Tsuji and Yoshiko Matsuda :
プロセシング酵素PACE4Eのラット脳発生過程での発現,
日本生化学会第69回大会・日本分子生物学会第19回年会合同年会, Aug. 1996.
48. Tetsuya Akamatsu, 吉田 茂, 水野 勝弘, 長田 香弥, 米本 佳余子, 森 健二, Hideaki Nagamune, Akihiko Tsuji, Eric Grouzmann and Yoshiko Matsuda :
Kexin様プロテアーゼPC7の中枢神経系における細胞特異的発現,
日本生化学会第68回大会, Sep. 1995.
49. Akihiko Tsuji, Hideaki Nagamune, Tetsuya Akamatsu, 日根 智恵美, 村松 和明, 森 健二, 玉井 靖啓, 米本 佳余子 and Yoshiko Matsuda :
新Kexin様プロテアーゼの構造と組織分布,
日本先天代謝異常学会第36回大会, Nov. 1994.
50. Tetsuya Akamatsu, 今村 恵美, Hideaki Nagamune, Akihiko Tsuji and Yoshiko Matsuda :
新しいkexinファミリープロテアーゼPC7の細胞特異的発現-in situ hybridizationによる解析,
日本細胞生物学会第47回大会, Sep. 1994.
51. 玉井 靖啓, 村松 和明, Tetsuya Akamatsu, 日根 智恵美, 森 健二, Hideaki Nagamune, Akihiko Tsuji, Keisuke Izumi and Yoshiko Matsuda :
新ペプチドホルモンプロセッシングプロテアーゼPACE4Cの細胞特異的発現,
日本細胞生物学会第47回大会, Sep. 1994.
52. Hideaki Nagamune, Akihiko Tsuji, 村松 和明, Tetsuya Akamatsu, 東根 一也, 日根 智恵美, Keisuke Izumi, 坂口 剛正, 吉田 哲也, Sumihare Noji and Yoshiko Matsuda :
甲状腺傍濾胞細胞におけるサチラーゼファミリープロテアーゼの発現,
日本生化学会第66回大会, Oct. 1993.
53. Tetsuya Akamatsu, Akihiko Tsuji, Hideaki Nagamune and Yoshiko Matsuda :
ラット肝α-マクログロブリン-プロテアーゼ複合体の性質,
日本生化学会第65回大会, Oct. 1992.
54. Akihiko Tsuji, Tetsuya Akamatsu, 尾田 領一, Hideaki Nagamune and Yoshiko Matsuda :
ラット肝α-マクログロブリン-プロテアーゼ複合体の性質,
日本生化学会中四国支部第55回例会, Apr. 1992.
55. Koji Kishimoto, 辻 昭彦, Yoshiko Matsuda and 勝沼 信彦 :
ラットジストロフィンの精製とタンパク特性,
第63回日本生化学会大会(口頭), Sep. 1990.

Et cetera, Workshop:

1. Yoshiko Matsuda :
α2-マクログロブリンをキャリアーとした肝指向性ドラッグデリバリーシステムの開発,
長瀬科学技術振興財団研究報告集, Vol.8, 147-157, Dec. 1996.

Patent:

1. Yoshiko Matsuda and Akihiko Tsuji : ズブチリシン様プロプロテインコンベルターゼ·PACE4に対するモノクローナル抗体及びその利用, 2002-292869 (Oct. 2002), .