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Tokushima University > Institute of Advanced Medical Sciences > 重点研究部門 > (Files for researchmap) [PDF manual] [Auto-propagate to researchmap]

Research Activity

His Web Page

Field of Study

Medicine

Subject of Study

Book / Paper

Book:

1. Hiroshi Kido :
唾液を用いたアレルギー診断,非侵襲的検体検査の最前線,
2015.
2. Hiroshi Kido :
カルニチンパルミトイルトランスフェラーゼII欠損症,
Mar. 2013.

Academic Paper (Judged Full Paper):

1. Junji Chida, Hideyuki Hara, Keiji Uchiyama, Etsuhisa Takahashi, Hironori Miyata, Hidetaka Kosako, Yukiko Tomioka, Toshihiro Ito, Hiroyuki Horiuchi, Haruo Matsuda, Hiroshi Kido and Suehiro Sakaguchi :
Prion protein signaling induces M2 macrophage polarization and protects from lethal influenza infection in mice.,
PLoS Pathogens, Vol.16, No.8, e1008823, 2020.
(DOI: 10.1371/journal.ppat.1008823,   PubMed: 32845931)
2. Makoto Irahara, Wakako Shinahara, Mayumi Sugimoto, Yukiko Ogawa, Keiji Shitsukawa, Kenji Kubota, Yukihiro Ohya, Hirohisa Saito, Shoji Kagami and Hiroshi Kido :
Ovomucoid-specific IgG4 level in cord blood associates negatively with later sensitization.,
Pediatric Allergy and Immunology, Vol.30, No.8, 857-860, 2019.
(DOI: 10.1111/pai.13116,   PubMed: 31441111)
3. Makoto Irahara, Wakako Shinahara, Mayumi Sugimoto, Yukiko Ogawa, Keiji Shitsukawa, Kenji Kubota, Limin Yang, Yukihiro Ohya, Hirohisa Saito, Shoji Kagami, Kokichi Arisawa and Hiroshi Kido :
Trajectories of class-switching-related egg and cow's milk allergen-specific immunoglobulin isotype formation and its modification by eczema with low- and high-affinity immunoglobulin E during early infancy,
Immunity, Inflammation and Disease, Vol.7, No.2, 74-85, 2019.
(Tokushima University Institutional Repository: 114285,   DOI: 10.1002/iid3.245,   PubMed: 30859748,   Elsevier: Scopus)
4. Takashi Kimoto, Hyejin Kim, Satoko Sakai, Etsuhisa Takahashi and Hiroshi Kido :
Oral vaccination with influenza hemagglutinin combined with human pulmonary surfactant-mimicking synthetic adjuvant SF-10 induces efficient local and systemic immunity compared with nasal and subcutaneous vaccination and provides protective immunity in mice.,
Vaccine, Vol.37, No.4, 612-622, 2019.
(DOI: 10.1016/j.vaccine.2018.12.002,   PubMed: 30553569,   Elsevier: Scopus)
5. Jun Oda, Yukioka Tetsu, Kazunari Azuma, Takao Arai, Junji Chida and Hiroshi Kido :
Endogenous genetic risk factor for serious heatstroke: the thermolabile phenotype of carnitine palmitoyltransferase II variant.,
Acute Medicine & Surgery, Vol.6, No.1, 25-29, 2018.
(DOI: 10.1002/ams2.373,   PubMed: 30651994)
6. Junji Chida, Hideyuki Hara, Masashi Yano, Keiji Uchiyama, Rani Nandita Das, Etsuhisa Takahashi, Hironori Miyata, Yukiko Tomioka, Toshihiro Ito, Hiroshi Kido and Suehiro Sakaguchi :
Prion protein protects mice from lethal infection with influenza A viruses.,
PLoS Pathogens, Vol.14, No.5, e1007049, 2018.
(Tokushima University Institutional Repository: 112206,   DOI: 10.1371/journal.ppat.1007049,   PubMed: 29723291)
7. Norio Kawamoto, Norio Kamemura, Hiroshi Kido and Toshiyuki Fukao :
Detection of ovomucoid-specific low-affinity IgE in infants and its relationship to eczema.,
Pediatric Allergy and Immunology, Vol.28, No.4, 355-361, 2017.
(DOI: 10.1111/pai.12702,   PubMed: 28140473,   Elsevier: Scopus)
8. Shima Atsushi, Yasuno Tetsuhiko, Kohno Ryuichi, Yamada Kenji, Yamaguchi Seiji, Yamaguchi Miyoko, Hiroshi Kido and Fukuda Hideyoshi :
First Japanese Case of Carnitine Palmitoyltransferase II Deficiency with the Homozygous Point Mutation S113L,
Internal Medicine, Vol.55, No.18, 2659-2661, 2016.
(DOI: 10.2169/internalmedicine.55.6288,   Elsevier: Scopus)
9. Hiroshi Kido, Indalao L. Irene, Kim Hyejin, Kimoto Takashi, Sakai Satoko and Etsuhisa Takahashi :
Energy metabolic disorder is a major risk factor in severe influenza virus infection: Proposals for new therapeutic options based on animal model experiments,
Respiratory Investigation, Vol.54, No.5, 312-319, 2016.
(DOI: 10.1016/j.resinv.2016.02.007,   PubMed: 27566378)
10. Dai Mizuno, Takashi Kimoto, Satoko Sakai, Etsuhisa Takahashi, Hyejin Kim and Hiroshi Kido :
Induction of systemic and mucosal immunity and maintenance of its memory against influenza A virus by nasal vaccination using a new mucosal adjuvant SF-10 derived from pulmonary surfactant in young cynomolgus monkeys,
Vaccine, Vol.34, No.16, 1881-1888, 2016.
(DOI: 10.1016/j.vaccine.2016.02.061,   PubMed: 26954466,   Elsevier: Scopus)
11. Mayumi Sugimoto, Norio Kamemura, Mizuho Nagao, Makoto Irahara, Shoji Kagami, Takao Fujisawa and Hiroshi Kido :
Differential response in allergen-specific IgE, IgGs and IgA levels for predicting outcome of oral immunotherapy.,
Pediatric Allergy and Immunology, Vol.27, No.3, 276-282, 2016.
(Tokushima University Institutional Repository: 109691,   DOI: 10.1111/pai.12535,   PubMed: 26764899,   Elsevier: Scopus)
12. Shoji Masaki, Arakai Yumie, Esumi Tomoyuki, Konami Shuntaro, Yamamoto Chihiro, Suzaki Yutaka, Etsuhisa Takahashi, Konishi Shiro, Hiroshi Kido and Kuzuhara Takashi :
Bakuchiol is a phenolic isoprenoid with novel enantiomer-selective anti-influenza A virus activity involving Nrf2 activation,
The Journal of Biological Chemistry, Vol.290, No.46, 28001-28017, 2015.
(DOI: 10.1074/jbc.M115.669465,   PubMed: 26446794,   Elsevier: Scopus)
13. Hiroshi Kido :
Influenza virus pathogenicity regulated by host cellular proteases, cytokines and metabolites, and its therapeutic options,
Proceedings of the Japan Academy. Series B, Physical and biological sciences, Vol.91, No.8, 351-368, 2015.
(DOI: 10.2183/pjab.91.351,   PubMed: 26460316,   Elsevier: Scopus)
14. Yao Min, Cai Min, Yao Dengfu, Xu Xi, Yang Rongrong, Li Yuting, Zhang Yuanyuan, Hiroshi Kido and Yao Dengbing :
Abbreviated half-lives and impaired fuel utilization in carnitine palmitoyltransferase II variant fibrobrasts,
PLoS ONE, Vol.10, No.3, e0119936, 2015.
(Tokushima University Institutional Repository: 114928,   DOI: 10.1371/journal.pone.0119936,   PubMed: 25781464)
15. Maekawa Toshihiro, Kimoto Takashi, Dai Mizuno, Furukawa Yuichi, Ida Masayuki, Etsuhisa Takahashi, Izumo Takayuki, Ono Yoshiko, Shibata Hiroshi and Hiroshi Kido :
Oral Administration of Lactobacillus pentosus Strain S-PT84 Enhances Anti-Influenza Virus-Specific IgG Production in Plasma after Limited Doses of Influenza Virus Vaccination in Mice,
Journal of Vaccine & Immunotechnology, Vol.2, No.1, 2015.
16. Norio Kamemura, Miwa Takashima, Hideaki Morita, Kenji Matsumoto, Hirohisa Saito and Hiroshi Kido :
Measurement of allergen-specific secretory IgA in stool of neonates, infants and toddlers by protection against degradation of immunoglobulins and allergens.,
The Journal of Medical Investigation : JMI, Vol.62, No.3-4, 137-144, 2015.
(Tokushima University Institutional Repository: 109361,   DOI: 10.2152/jmi.62.137,   PubMed: 26399337)
17. Mineyoshi Hiyoshi, I.L Indalao, Mihiro Yano, Kazuhiko Yamane, Etsuhisa Takahashi and Hiroshi Kido :
Influenza A virus infection of vascular endothelial cells induces GSK-3β-mediated β-catenin degradation in adherens junctions, with a resultant increase in membrane permeability.,
Archives of Virology, Vol.160, No.1, 225-234, 2014.
(Tokushima University Institutional Repository: 114996,   DOI: 10.1007/s00705-014-2270-5,   PubMed: 25385175)
18. Pan Hai-Yan, Sun Hua-Mei, Xue Lu-jing, Pan Min, Wang Yi-Ping, Hiroshi Kido and Zhu Jian-Hua :
Ectopic trypsin in the myocardium promotes dilated cardiomyopathy after influenza A virus infection,
American Journal of Physiology, Heart and Circulatory Physiology, Vol.307, No.6, H922-H932, 2014.
(DOI: 10.1152/ajpheart.00076.2014,   PubMed: 25038143)
19. Yamane Kazuhiro, Indalao L. Irene, Junji Chida, Yamamoto Yoshikazu, Hanawa Masaaki and Hiroshi Kido :
Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza,
PLoS ONE, Vol.9, No.5, e98032, 2014.
(Tokushima University Institutional Repository: 106308,   DOI: 10.1371/journal.pone.0098032,   PubMed: 24865588,   Elsevier: Scopus)
20. Endo Hiroshi, Mihiro Yano, Yuushi Okumura and Hiroshi Kido :
Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 70,
Cell Death & Disease, Vol.5, e1027, 2014.
(DOI: 10.1038/cddis.2013.550,   PubMed: 24481441,   Elsevier: Scopus)
21. Kimoto Takashi, Dai Mizuno, Takei Tsunetomo, Kunimi Takuya, Ono Shinji, Sakai Satoko and Hiroshi Kido :
Intranasal influenza vaccination using a new synthetic mucosal adjuvant SF-10: induction of potent local and systemic immunity with balanced Th1 and Th2 responses,
Influenza and Other Respiratory Viruses, Vol.7, No.6, 1218-1226, 2013.
(DOI: 10.1111/irv.12124,   PubMed: 23710832,   Elsevier: Scopus)
22. W Shinahara, Etsuhisa Takahashi, T Sawabuchi, M Arai, N Hirotsu, Y Takasaki, S Shindo, K Shibao, T Yokoyama, K Nishikawa, M Mino, M Iwaya, Y Yamashita, S Suzuki, Dai Mizuno and Hiroshi Kido :
Immunomodulator clarithromycin enhances mucosal and systemic immune responses and reduces re-infection rate in pediatric patients with influenza treated with antiviral neuraminidase inhibitors: a retrospective analysis.,
PLoS ONE, Vol.8, No.7, e70060, 2013.
(DOI: 10.1371/journal.pone.0070060,   PubMed: 23875018,   Elsevier: Scopus)
23. M Shoji, Etsuhisa Takahashi, D Hatakeyama, Y Iwai, Y Morita, R Shirayama, N Echigo, Hiroshi Kido, S Nakamura, T Mashino, T Okutani and T Kuzuhara :
Anti-Influenza Activity of C60 Fullerene Derivatives.,
PLoS ONE, Vol.8, No.6, e66337, 2013.
(DOI: 10.1371/journal.pone.0066337,   PubMed: 23785493,   Elsevier: Scopus)
24. Masahiro Inoue, Kouichi Yasuda, Haruki Uemura, Natsumi Yasaka, Achim Schnaufer, Mihiro Yano, Hiroshi Kido, Daisuke Kohda, Hirofumi Doi, Toshihide Fukuma, Akihiko Tsuji and Nobuo Horikoshi :
Trypanosoma brucei 14-3-3I and II proteins predominantly form a heterodimer structure that acts as a potent cell cycle regulator in vivo.,
The Journal of Biochemistry, Vol.153, No.5, 431-439, 2013.
(DOI: 10.1093/jb/mvt016,   PubMed: 23457405,   Elsevier: Scopus)
25. Junji Chida, Rie Ono, Kazuhiko Yamane, Mineyoshi Hiyoshi, Masaji Nishimura, Mutsuo Onodera, Emiko Nakataki, Shichijo Koichi, Matsushita Masatomo and Hiroshi Kido :
Blood lactate/ATP ratio, as an alarm index and real-time biomarker in critical illness,
PLoS ONE, Vol.8, No.4, e60561, 2013.
(DOI: 10.1371/journal.pone.0060561,   PubMed: 23577122,   Elsevier: Scopus)
26. Etsuhisa Takahashi, Kosuke Kataoka, Irene L. Indalao, Keiko Konoha, Kazuyuki Fujii, Junji Chida, Dai Mizuno, Kohtaro Fujihashi and Hiroshi Kido :
Oral clarithromycin enhances airway immunoglobulin A (IgA) immunity through induction of IgA class switching recombination and B-cell-activating factor of the tumor necrosis factor family molecule on mucosal dendritic cells in mice infected with influenza A virus.,
Journal of Virology, Vol.86, No.20, 10924-10934, 2012.
(DOI: 10.1128/JVI.01207-12,   PubMed: 22896605)
27. Ishii Ayumi, Kaminori Kanae, Mineyoshi Hiyoshi, Hiroshi Kido, Ohta Takeshi and Hiroaki Konishi :
Inhibitory effect of SPE-39 due to tyrosine phosphorylation and ubiquitination on the function of Vps33B in the EGF-stimulated cells,
FEBS Letters, Vol.586, No.16, 2245-2250, 2012.
(DOI: 10.1016/j.febslet.2012.05.051,   PubMed: 22677173,   Elsevier: Scopus)
28. Cisa Fujimoto, Noriaki Takeda, A Matsunaga, A Sawada, T Tanaka, Takashi Kimoto, Wakako Shinahara, Takako Sawabuchi, Miyoko Yamaguchi, M Hayama, Hiroaki Yanagawa, Mihiro Yano and Hiroshi Kido :
Induction and maintenance of anti-influenza antigen-specific nasal secretory IgA levels and serum IgG levels after influenza infection in adults.,
Influenza and Other Respiratory Viruses, Vol.6, No.6, 396-403, 2012.
(DOI: 10.1111/j.1750-2659.2011.00330.x,   PubMed: 22226319)
29. Norio Kamemura, Hitomi Tada, Naoki Shimojo, Yoshinori Morita, Yoichi Kohno, Takao Ichioka, Koichi Suzuki, Kenji Kubota, Mineyoshi Hiyoshi and Hiroshi Kido :
Intrauterine sensitization of allergen-specific IgE analyzed by a highly sensitive new allergen microarray.,
The Journal of Allergy and Clinical Immunology, Vol.130, No.1, 113-21.e2, 2012.
(DOI: 10.1016/j.jaci.2012.02.023,   PubMed: 22464644)
30. Masaya Kubota, Junji Chida, Hideki Hoshino, Hiroshi Ozawa, Ayaka Koide, Hirohumi Kashii, Akiko Koyama, Yoko Mizuno, Ai Hoshino, Yamaguchi Miyoko, Dengbing Yao, Min Yao and Hiroshi Kido :
Thermolabile CPT II variants and low blood ATP levels are closely related to severity of acute encephalopathy in Japanese children,
Brain & Development, Vol.34, No.1, 20-27, 2012.
(DOI: 10.1016/j.braindev.2010.12.012,   PubMed: 21277129,   CiNii: 10031049391)
31. Hiroshi Kido, Yuushi Okumura, Etsuhisa Takahashi, Haiyan Pan, Siye Wang, Dengbing Yao, Min Yao, Junji Chida and Mihiro Yano :
Role of host cellular proteases in the pathogenesis of influenza and influenza-induced multiple organ failure,
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Vol.1824, No.1, 186-194, 2012.
(DOI: 10.1016/j.bbapap.2011.07.001,   PubMed: 21801859)
32. Cisse Youssouf, Isao Inoue and Hiroshi Kido :
Oseltamivir reduces hippocampal abnormal EEG activities after influenza A virus infection in isoflurane-anesthetized rats,
Journal of Experimental Pharmacology, Vol.4, 69-76, 2012.
(DOI: 10.2147/JEP.S29769)
33. Koichi Suzuki, Mineyoshi Hiyoshi, Hitomi Tada, Miwa Bando, Takao Ichioka, Norio Kamemura and Hiroshi Kido :
Allergen diagnosis microarray with high-density immobilization capacity using diamond-like carbon-coated chips for profiling allergen-specific IgE and other immunoglobulins,
Analytica Chimica Acta, Vol.706, No.2, 321-327, 2011.
(DOI: 10.1016/j.aca.2011.08.034,   PubMed: 22023868)
34. Min Yao, Dengbing Yao, Miyoko Yamaguchi, Junji Chida, Dengfu Yao and Hiroshi Kido :
Bezafibrate upregulates carnitine palmitoyltransferase II expression and promotes mitochondrial energy crisis dissipation in fibroblasts of patients with influenza-associated encephalopathy,
Molecular Genetics and Metabolism, Vol.104, No.3, 265-272, 2011.
(DOI: 10.1016/j.ymgme.2011.07.009,   PubMed: 21816645)
35. Dengbing Yao, Min Yao, Miyoko Yamaguchi, Junji Chida and Hiroshi Kido :
Characterization of compound missense mutation and deletion of carnitine palmitoyltransferase II in a patient with adenovirus-associated encephalopathy,
The Journal of Medical Investigation : JMI, Vol.58, No.3,4, 210-218, 2011.
(Tokushima University Institutional Repository: 83835,   DOI: 10.2152/jmi.58.210,   PubMed: 21921422)
36. Hiroshi Kido :
熱中症の新しいリスクファクターとしての熱不安定性フェノタイプ症,
Journal of Japanese Association for Acute Medicine, Vol.22, No.7, 350-351, 2011.
(DOI: 10.3893/jjaam.22.350,   CiNii: 10029530032)
37. Saori Takeda, Ai Fujimoto, Emiko Yamauchi, Mineyoshi Hiyoshi, Hiroshi Kido, Takashi Watanabe, Kozo Kaibuchi, Takeshi Ohta and Hiroaki Konishi :
Role of a tyrosine phosphorylation of SMG-9 in binding of SMG-9 to IQGAP and the NMD complex,
Biochemical and Biophysical Research Communications, Vol.410, No.1, 29-33, 2011.
(DOI: 10.1016/j.bbrc.2011.05.099,   PubMed: 21640080,   Elsevier: Scopus)
38. Dai Mizuno, Tunetomo Takei, Akiho Fukuta, Wakako Shinahara, Etsuhisa Takahashi, Mihiro Yano and Hiroshi Kido :
Surfactant protein C is an essential constituent for mucosal adjuvanticity of Surfacten, acting as an antigen delivery vehicle and inducing both local and systemic immunity,
Vaccine, Vol.29, No.33, 5368-5378, 2011.
(DOI: 10.1016/j.vaccine.2011.05.090,   PubMed: 21669246)
39. Hiroshi Kido, Etsuhisa Takahashi, Kosuke Kataoka, Kazuyuki Fujii, Satoshi Suzuki, Kazuhiro Iwase and Chika Ito :
Attenuation of respiratory immune responses by antiviral neuraminidase inhibitor treatment and boost of mucosal immunoglobulin A response by co-administration of immuno- modulator clarithromycin in paediatric influenza.,
Influenza and Other Respiratory Viruses, Vol.5, No.1, 240-243, 2011.
40. Etsuhisa Takahashi, Yuushi Okumura and Hiroshi Kido :
Activation of the highly pathogenic avian influenza virus replication by membrane-bound proteases MSPL and TMPRSS13 and its inhibition by the protease inhibitors,
Influenza and Other Respiratory Viruses, Vol.5, No.1, 276-279, 2011.
41. Junji Chida, Siye Wang, Pan Hai-Yan, Le Quang Trong and Hiroshi Kido :
Influenza virus-cytokine-protease cycles are principal mechanisms of multi-organ failure in severe influenza and therapeutic approaches,
Influenza and Other Respiratory Viruses, Vol.5, No.1, 281-286, 2011.
42. Pan Hai-Yan, Mihiro Yano and Hiroshi Kido :
Effects of inhibitors of Toll-like receptors, protease-activated receptor-2 signalings and trypsin on influenza A virus replication and upregulation of cellular factors in cardiomyocytes,
The Journal of Medical Investigation : JMI, Vol.58, No.1,2, 19-28, 2011.
(Tokushima University Institutional Repository: 74742,   DOI: 10.2152/jmi.58.19,   PubMed: 21372483)
43. Hiroshi Kido and Kazumi Ishidoh :
Nobuhiko Katunuma: an outstanding scientist in the field of proteolysis and warm-hearted 'Kendo Fighter' biochemist.,
The Journal of Biochemistry, Vol.148, No.5, 527-531, 2010.
(DOI: 10.1093/jb/mvq109,   PubMed: 20980477)
44. Hai-Yan Pan, Hirotsugu Yamada, Junji Chida, Siye Wang, Mihiro Yano, Min Yao, Jianhua Zhu and Hiroshi Kido :
Up-regulation of ectopic trypsins in the myocardium by influenza A virus infection triggers acute myocarditis,
Cardiovascular Research, Vol.89, No.3, 595-603, 2010.
(DOI: 10.1093/cvr/cvq358,   PubMed: 21084314)
45. Siye Wang, Le Quang Trong, Kurihara Naoki, Junji Chida, Youssouf Cisse, Mihiro Yano and Hiroshi Kido :
Influenza Virus Cytokine Protease Cycle in the Pathogenesis of Vascular Hyperpermeability in Severe Influenza,
The Journal of Infectious Diseases, Vol.202, No.7, 991-1001, 2010.
(DOI: 10.1086/656044,   PubMed: 20731583)
46. Etsuhisa Takahashi, Kosuke Kataoka, Kazuyuki Fujii, Junji Chida, Dai Mizuno, Makoto Fukui, Hiro-O Ito, Kohtaro Fujihashi and Hiroshi Kido :
Attenuation of inducible respiratory immune responses by oseltamivir treatment in mice infected with influenza A virus.,
Microbes and Infection, Vol.12, No.10, 778-783, 2010.
(DOI: 10.1016/j.micinf.2010.04.013,   PubMed: 20452454)
47. Yuushi Okumura, Etsuhisa Takahashi, Mihiro Yano, Ohuchi Masanobu, Daidoji Tomo, Nakaya Takaaki, Bőttcher Eva, Garten Woflgang, Klenk Hans-Dieter and Hiroshi Kido :
Novel type II transmembrane serine proteases, MSPL and TMPRSS13, proteolytically activate membrane fusion activity of hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication.,
Journal of Virology, Vol.84, No.10, 5089-5096, 2010.
(DOI: 10.1128/JVI.02605-09,   PubMed: 20219906)
48. Youssouf Cisse, Siye Wang, Isao Inoue and Hiroshi Kido :
Rat model of influenza-associated encephalopathy (IAE): studies of electroencephalogram (EEG) in vivo,
Neuroscience, Vol.165, No.4, 1127-1137, 2010.
(DOI: 10.1016/j.neuroscience.2009.10.062,   PubMed: 19892004)
49. Siye Wang, Le Quang Trong, Junji Chida, Youssouf Cisse, Mihiro Yano and Hiroshi Kido :
Meckanisms of matrix metallo protease-9 wuregulation and tissue desfruction in rarious organs in influenza A virus infection,
The Journal of Medical Investigation : JMI, Vol.57, No.1,2, 26-34, 2010.
(DOI: 10.2152/jmi.57.26,   PubMed: 20299740)
50. Yiu-Wing Kam, Yuushi Okumura, Hiroshi Kido, Lisa P. F. Ng, Roberto Bruzzone and Ralf Altmeyer :
Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial,
PLoS ONE, Vol.4, No.11, e7870, 2009.
(DOI: 10.1371/journal.pone.0007870,   PubMed: 19924243)
51. Sawabuchi Takako, Suzuki Satoshi, Isase Kazuhiro, Ito Chika, Dai Mizuno, Todari Hajime, Watanabe Isamu, Talukder R. Sadiqur, Junji Chida and Hiroshi Kido :
Boost of mucosal secretory immunoglobulin A response by clarithromycin in paediatric influenza,
Respirology, Vol.14, No.8, 1173-1179, 2009.
(DOI: 10.1111/j.1440-1843.2009.01639.x,   PubMed: 19909463)
52. Maki Nisino, Dai Mizuno, Kimoto Takashi, Shinahara Wakako, Fukuta Akiho, Tunetomo Takei, Kaori Sumida, Seiichiro Kitamura, Hiroshi Shiota and Hiroshi Kido :
Influenza vaccine with Surfacten, a modified pulmonary surfactant, induces systemic and mucosal immune responses without side effects in minipigs,
Vaccine, Vol.27, No.41, 5620-5627, 2009.
(DOI: 10.1016/j.vaccine.2009.07.024,   PubMed: 19647064)
53. Mineyoshi Hiyoshi, Hiroaki Konishi, Hirokazu Uemura, Hideki Matsuzaki, Hideo Tsukamoto, Ryusuke Sugimoto, Hideo Takeda, Satoru Dakeshita, Atsushi Kitayama, Hidenobu Takami, Fusakazu Sawachika, Hiroshi Kido and Kokichi Arisawa :
D-dopachrome tautomerase is a candidate for key proteins to protect the rat liver damaged by carbon tetrachloride,
Toxicology, Vol.255, No.1,2, 6-14, 2009.
(DOI: 10.1016/j.tox.2008.09.016,   PubMed: 18930782)
54. Hiroshi Kido, Yuushi Okumura, Etsuhisa Takahashi, HY Pan, Siye Wang, Junji Chida, Le Trong Quang and Mihiro Yano :
Host envelope glycoprotein processing proteases are indispensable for entry into human cells by seasonal and highly pathogenic avian influenza viruses.,
Journal of Molecular and Genetic Medicine, Vol.3, No.1, 167-175, 2009.
(PubMed: 19565019)
55. Fujimoto Chisa, Hiroshi Kido, Sawabuchi Takako, Dai Mizuno, Hayama Masaki, Hiroaki Yanagawa and Noriaki Takeda :
Evaluation of nasal IgA secretion in normal subjects by nasal spray and aspiration.,
Auris, Nasus, Larynx, Vol.36, No.3, 300-304, 2009.
(DOI: 10.1016/j.anl.2008.09.005,   PubMed: 19013037)
56. Daisuke Hashimoto, Masaki Ohmuraya, Masahiko Hirota, Akitsugu Yamamoto, Koichi Suyama, Satoshi Ida, Yuushi Okumura, Etsuhisa Takahashi, Hiroshi Kido, Kimi Araki, Hideo Baba, Noboru Mizushima and Ken-ichi Yamamura :
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells,
The Journal of Cell Biology, Vol.18, No.7, 1065-1072, 2008.
(DOI: 10.1083/jcb.200712156,   PubMed: 18591426)
57. Shinichi Nakamuta, Hiroshi Endo, Youichiro Higashi, Aoi Kousaka, Aoi Kousaka, Mihiro Yano and Hiroshi Kido :
HIV-1 gp120-mediated disruption of tight junction proteins by induction of proteasome-mediated degradation of zonula occludens-1 and -2 in human brain microvascular endothelial cells,
Journal of NeuroVirology, Vol.14, No.3, 186-195, 2008.
(DOI: 10.1080/13550280801993630,   PubMed: 18569453)
58. Dengbing Yao, Hiroshi Mizuguchi, Miyoko Yamaguchi, Hiroshi Yamada, Junji Chida, Koji Shikata and Hiroshi Kido :
Thermal instability of compound variants of carnitine palmitoyltransferase II and impaired mitochondrial fuel utilization in influenza-associated encephalopathy.,
Human Mutation, Vol.29, No.5, 718-727, 2008.
(DOI: 10.1002/humu.20717,   PubMed: 18306170)
59. Hiroshi Kido and Yuushi Okumura :
MSPL/TMPRSS13,
Frontiers in Bioscience, Vol.13, 754-758, 2008.
(DOI: 10.2741/2717,   PubMed: 17981585)
60. Masamichi Kuwajima, Hiroaki Fujihara, Hiroyoshi Sei, Asako Umehara, Masako Sei, Tomi T. Tsuda, Akiko Sukeno, Tatsuya Okamoto, Akiko Inubushi, Yoichi Ueta, Toshio Doi and Hiroshi Kido :
Reduced carnitine level causes death from hypoglycemia: possible involvement of suppression of hypothalamic orexin expression during weaning period.,
Endocrine Journal, Vol.54, No.6, 911-925, 2007.
(DOI: 10.1507/endocrj.K07-044,   PubMed: 18025760)
61. Masaki Hayama, Yuushi Okumura, Etsuhisa Takahashi, Aki Shimabukuro, Manabu Tamura, Noriaki Takeda, Takeshi Kubo and Hiroshi Kido :
Identification and analysis of the promoter region of the type II transmembrane serine protease polyserase-1 and its transcript variants,
Biological Chemistry, Vol.388, No.8, 853-858, 2007.
(DOI: 10.1515/BC.2007.093,   PubMed: 17655505,   Elsevier: Scopus)
62. Mihiro Yano, Nakamuta Shinichi, Shiota Mayumi, Endo Hiroshi and Hiroshi Kido :
Gatekeeper Role of 14-3-3τ Protein in HIV-1 gp120-Mediated Apotosis of Human Endothelial Cells by Inactivation of Bad,
AIDS, Vol.21, No.8, 911-920, 2007.
(DOI: 10.1097/QAD.0b013e32810539f3,   PubMed: 17457084)
63. Hiroshi Kido, Yuushi Okumura, Hiroshi Yamada, Le Q. Trong and Mihiro Yano :
Proteases Essential for Human Influenza Virus Entry into Cells and Their Inhibitors as Potential Therapeutic Agents,
Current Pharmaceutical Design, Vol.13, No.4, 405-414, 2007.
(DOI: 10.2174/138161207780162971,   PubMed: 17311557)
64. Yuushi Okumura, M Hayama, Etsuhisa Takahashi, M Fujiuchi, A Shimabukuro, Mihiro Yano and Hiroshi Kido :
Serase-1B, a new splice variant of polyserase-1/TMPRSS9, activates urokinase-type plasminogen activator and the proteolytic activation is negatively regulated by glycosaminoglycans.,
The Biochemical Journal, Vol.400, No.3, 551-561, 2006.
(DOI: 10.1042/BJ20060212,   PubMed: 16872279)
65. Mineyoshi Hiyoshi, Hirokazu Uemura, Hideo Takeda, Hiroshi Kido and Kokichi Arisawa :
[Introduction of proteomic approach to environmental medicine].,
Nihon Eiseigaku Zasshi, Vol.61, No.4, 393-399, 2006.
(DOI: 10.1265/jjh.61.393,   PubMed: 17025216)
66. Yuushi Okumura and Hiroshi Kido :
Physiological roles of the type II transmembrane serine protease,
Seikagaku, Vol.78, No.12, 1155-1159, 2006.
(PubMed: 17243636,   CiNii: 10018675676)
67. Dengfu Yao, Masamichi Kuwajima, Chen Ye, Mayumi Shiota, Yuushi Okumura, Hiroshi Yamada and Hiroshi Kido :
Impaired long-chain fatty acid metabolism in mitochondria causes brain vascular invasion by a non-neurotropic epidemic influenza A virus in the newborn/suckling period: implications for influenza-associated encephalopathy,
Molecular and Cellular Biochemistry, Vol.299, No.1-2, 85-92, 2006.
(DOI: 10.1007/s11010-005-9046-x,   PubMed: 16896540,   Elsevier: Scopus)
68. Mihiro Yano, Naoki Muguruma, Susumu Ito, Eriko Aoyagi, Tetsuo Kimura, Yoshitaka Imoto, Jianxin Cao, Shohei Inoue, Shigeki Sano, Yoshimitsu Nagao and Hiroshi Kido :
Fab fragment labeled with ICG-derivative for detecting digestive tract cancer,
Photodiagnosis and Photodynamic Therapy, Vol.3, No.3, 177-183, 2006.
(DOI: 10.1016/j.pdpdt.2006.03.012)
69. Hiroshi Kido, 水野 大, 西野 真紀, 臼木 孝行 and 武井 恒知 :
肺サーファクタントの粘膜アジュバント作用,
臨床免疫·アレルギー科, Vol.46, No.4, 411-415, 2006.
70. Mihiro Yano, Nakamuta S., Wu X., Yuushi Okumura and Hiroshi Kido :
A novel function of 14-3-3 protein: 14-3-3z is a heat shock-related molecular chaperone that dissolves thermal-aggregated proteins,
Molecular Biology of the Cell, Vol.17, No.11, 4769-4779, 2006.
(DOI: 10.1091/mbc.E06-03-0229,   PubMed: 16943323)
71. Hiroshi Kido, Le Quang Trong, Yao Dengbing, Hiroshi Yamada, Wang Sie and Yuushi Okumura :
インフルエンザウイルス感染の病態とプロテアーゼによる重症化機構,
アレルギー·免疫, Vol.13, No.11, 1536-1544, 2006.
72. Hiroshi Yamada, Q.T. Le, A. Kousaka, Y. Higashi, M. Ttukane and Hiroshi Kido :
Sendai virus infection up-regulates trypsin I and matrix metalloproteinase-9, triggering viral multiplication and matrix degrdation in rat lungs and lung L2 cells,
Archives of Virology, Vol.151, No.12, 2529-2537, 2006.
(DOI: 10.1007/s00705-006-0807-y,   PubMed: 16816895)
73. K. Kunimi, M. Maegawa, M. Kamada, S. Yamamoto, T. Yasui, T. Matsuzaki, A. Kuwahara, H. Furumoto, Y. Ohmoto, Hiroshi Kido and M. Irahara :
Myeloid-related protein-8/14 is associated with proinflammatory cytokines in cervical mucus,
Journal of Reproductive Immunology, Vol.71, No.1, 3-11, 2006.
(DOI: 10.1016/j.jri.2005.12.010,   PubMed: 16806487)
74. Hiroshi Kido :
インフルエンザにおけるマクロライドの役割,
Japan Medicine, No.1005, 18, 2006.
75. Trong Q. Le, M. Kawachi, Hiroshi Yamada, M. Shiota, Yuushi Okumura and Hiroshi Kido :
Identification of Trypsin I as a candidate for influenza A virus and Sendai virus envelope glycoprotein processing protease in rat brain,,
Biological Chemistry, Vol.387, No.4, 467-475, 2006.
(DOI: 10.1515/BC.2006.062,   PubMed: 16606346)
76. 鈴木 悟, 岩瀬 一弘 and Hiroshi Kido :
小児インフルエンザ治療における抗ウイルス薬とマクロライド併用療法,,
感染と抗菌薬, Vol.9, No.2, 182-186, 2006.
77. Hiroshi Kido, Chen Ye, Yao Dengfu, 長南 律 and 塚根 まり子 :
インフルエンザ脳症の発症原因を探る-遺伝子多型と酵素機能解析から見たミトコンドリア脂肪酸代謝障害-,
化学と生物, Vol.44, No.2, 114-120, 2006.
(DOI: 10.1271/kagakutoseibutsu1962.44.114,   CiNii: 10017248035)
78. Y. Shiga, H. Wakabayashi, K. Miyazawa, Hiroshi Kido and Y. Itoyama :
14-3-3 Protein levels and isoform patterns in the cerebrospinal fluid of Creutzfeldt-Jakob diseasepatients in the progressive and terminal stages,
Journal of Clinical Neuroscience, Vol.13, No.6, 661-665, 2006.
(DOI: 10.1016/j.jocn.2005.09.004,   PubMed: 16815706)
79. Dai Mizuno, Itsuka Kubo, Mikiko Ide-Kurihara, Tomoko Ichinomiya and Hiroshi Kido :
Modified pulmonary surfactant is a potent adjuvant that stimulates the mucosal IgA production in response to the influenza virus antigen,
The Journal of Immunology, Vol.176, No.2, 1122-1130, 2006.
(PubMed: 16394001,   Elsevier: Scopus)
80. Hiroshi Kido, 廣津 伸夫 and 鈴木 悟 :
インフルエンザウイルス感染とクラリスロマイシン,
Medical Tribune, Vol.38, No.49, 62-63, 2005.
81. Hiroshi Kido :
肺の生体成分粘膜アジュバンドとインフルエンザ経鼻粘膜ワクチン,
Virus Report, Vol.2, No.2, 63-70, 2005.
82. 新田 麗子, 多田 仁美, 澤淵 貴子 and Hiroshi Kido :
ハイスループット食物アレルギー診断チップの開発-体質を映し出すテーラーメイド医療-,
IEICE Technical Report, Vol.105, No.222, 21-23, 2005.
83. A. Kurisaki, T. S. Hamazaki, K. Okabayashi, T. Iida, T. Nishine, R. Chonan, Hiroshi Kido, S. Tsunasawa, O. Nishimura, M. Asashima and H. Sugino :
Chromatin-related proteins in pluripotent mouse embryonic stem cells are downregulated after removal of leukemia inhibitory factor,
Biochemical and Biophysical Research Communications, Vol.335, No.3, 667-675, 2005.
(DOI: 10.1016/j.bbrc.2005.07.128,   PubMed: 16099433)
84. Hiroshi Kido, 水野 大 and 井手 美喜子 :
クラリスマイシンの粘膜免疫増張作用とインフルエンザウイルスの感染制御効果,
感染 炎症 免疫, Vol.35, No.4, 333-335, 2005.
85. Mihiro Yano, Y. Kanesaki, Y. Koumoto, M. Inoue and Hiroshi Kido :
Chaperone Activities of the 26S and 20S Proteasome,
Current Protein & Peptide Science, Vol.6, No.2, 197-203, 2005.
(DOI: 10.2174/1389203053545453,   PubMed: 15853655)
86. Hiroshi Kido :
病気への罹りやすさと重症度を左右する体内酵素—インフルエンザの感染感受性とインフルエンザ脳症の発症感受性を決める酵素群—,
第19回「大学と科学」公開シンポジウム講演収録集, 115-125, 2005.
87. Y. Chen, H. Mizuguchi, D. Yao, M. Ide, Y. Kuroda, Y. Shigematsu and Hiroshi Kido :
Thermolabile phenotype of carnitine palmitoyltransferase II variations as a predisposing factor for influenza-associated encephalopathy,
FEBS Letters, Vol.579, No.10, 2040-2044, 2005.
(DOI: 10.1016/j.febslet.2005.02.050,   PubMed: 15811315)
88. M. Kita, Yuushi Okumura, S. D. Ohdachi, Y. Oba, M. Yoshikuni, Y. Nakamura, Hiroshi Kido and D. Uemura :
Purification and characterization of brarinasin, a new tissue kallikurein-like protease from the short-tailed shrew Blarina brevicauda-comparative stadies with blarina toxin,
Biological Chemistry, Vol.386, No.2, 177-182, 2005.
(DOI: 10.1515/BC.2005.022,   PubMed: 15843162)
89. Degfu Yao, Ye Chen, Masamichi Kuwajima, Mayumi Shiota and Hiroshi Kido :
Accumulation of mini-plasmin in the cerebral capillaries causes vascular invasion of the murine brain by a pneumotropic influenza A virus: implications for influenza-associated encephalopathy,
Biological Chemistry, Vol.385, No.6, 487-492, 2004.
(DOI: 10.1515/BC.2004.057,   PubMed: 15255180)
90. Hiroshi Yamada, R. Chounan, Y. Higashi, N. Kurihara and Hiroshi Kido :
Mitochondrial targeting sequence of the influenza A virus PB1-F2 protein and its function in mitochondria,
FEBS Letters, Vol.578, No.3, 331-336, 2004.
(DOI: 10.1016/j.febslet.2004.11.017,   PubMed: 15589841)
91. Hiroshi Kido, Yuushi Okumura, Hiroshi Yamada, Dai Mizuno, Youichirou Higashi and Mihiro Yano :
Secretory leukoprotease inhibitor and pulmonary surfactant serve as principal defenses against influenza A virus infection in the airway and chemical agents up-regulating their levels may have therapeutic potential,
Biological Chemistry, Vol.385, No.11, 1029-1034, 2004.
(DOI: 10.1515/BC.2004.133,   PubMed: 15576322)
92. M. Kita, Y. Nakamura, Yuushi Okumura, S. D. Ohdachi, Y. Oba, M. Yoshikuni, Hiroshi Kido and D. Uemura :
Blarina toxin, a mammalian lethal venom from the short-tailed shrew Blarina brevicauda: Isolation and characterization,
Proceedings of the National Academy of Sciences of the United States of America, Vol.101, No.20, 7542-7547, 2004.
(DOI: 10.1073/pnas.0402517101,   PubMed: 15136743)
93. Hiroshi Kido :
クラリスロマイシンに気道の粘膜免疫増強作用,
Medical Tribune, Vol.37, No.42, 33, 2004.
94. Mihiro Yano, Y. Koumoto, Y. Kanesaki, Xueji Wu and Hiroshi Kido :
20S Proteasome prevents aggregation of heat-denatured proteins without PA700 regulatory subcomplex like a molecular chaperone,
Biomacromolecules, Vol.5, No.4, 1465-1469, 2004.
(DOI: 10.1021/bm049957a,   PubMed: 15244466)
95. Hiroshi Kido, Ye CHEN, Hiroshi Yamada and Yuushi Okumura :
インフルエンザウイルスの感染感受性と感染臓器特異性を決める個体のプロテアーゼ群,
Japanese Journal of Thrombosis and Hemostasis, Vol.15, No.4, 362-365, 2004.
(DOI: 10.2491/jjsth.15.362,   CiNii: 10016757196)
96. M. Sakai, H. Miyake, S. Tashiro, Yuushi Okumura and Hiroshi Kido :
Inhibitory effect of FK506 and Cyclosporine A on the growth and invation of human liver cancer cells,
The Journal of Medical Investigation : JMI, Vol.51, No.1-2, 63-69, 2004.
(Tokushima University Institutional Repository: 110716,   DOI: 10.2152/jmi.51.63,   PubMed: 15000258)
97. Hiroshi Kido, 山川 由美子, 多田 仁美, 澤淵 貴子, 水口 寛, 福田 陽司 and 木下 盛敏 :
ダイヤモンドコーティング高密度集積技術のプロテオミクス解析への応用,
NEW DIAMOND, Vol.33, No.3, 30-31, 2004.
98. Hiroshi Kido, Chen Ye, Hiroshi Yamada, 東 洋一郎 and 水野 大 :
インフルエンザ脳症の発症機序,
神経内科, Vol.60, No.2, 119-127, 2004.
99. Xueji Wu, Mihiro Yano, H. Washida and Hiroshi Kido :
The second metal-binding site of 70kDa heat-shock protein is essential for ADP-binding, ATP hydrolysis and ATP synthesis,
The Biochemical Journal, Vol.378, No.Pt 3, 793-799, 2004.
(DOI: 10.1042/BJ20031680,   PubMed: 14664695)
100. Ping Cui, Saimoon Sharmin, Yuushi Okumura, Hiroshi Yamada, Mihiro Yano, Dai Mizuno and Hiroshi Kido :
Endothelin-1 peptides and IL-5 synergistically increase the expression of IL-13 in eosinophils.,
Biochemical and Biophysical Research Communications, Vol.315, No.4, 782-787, 2004.
(DOI: 10.1016/j.bbrc.2004.01.168,   PubMed: 14985080)
101. Natsuo Oka, Yuushi Okumura, Hiro-omi Kanayama, Hirofumi Izaki, Masumi Okamoto, Hiroshi Kido and Susumu Kagawa :
Amiloride and Urinary Trypsin Inhibitor Inhibit Urothelial Cancer Invasion,
European Urology, Vol.44, No.6, 737-741, 2003.
(DOI: 10.1016/S0302-2838(03)00383-X,   PubMed: 14644129)
102. Eiko Murata, Saimoon Sharmin, Hiroshi Shiota, Mayumi Shiota, Mihiro Yano and Hiroshi Kido :
The effect of topically applied secretory leukocyte protease inhibitor on the eosinophil response in the late phase of allergic conjunctivitis,
Current Eye Research, Vol.26, No.5, 271-276, 2003.
(DOI: 10.1076/ceyr.26.4.271.15429,   PubMed: 12854054)
103. Yuushi Okumura, M. Nishikawa, Ping Cui, M. Shiota, Y. Nakamura, M. Adachi, K. Kitamura, K. Tomita and Hiroshi Kido :
Cloning and characterization of a novel transmembrane-type serine Protease from rat kidney, a new member among the sodium channel activators,
Biological Chemistry, Vol.384, No.10-11, 1483-1495, 2003.
(DOI: 10.1515/BC.2003.164,   PubMed: 14669991)
104. K. Hara, M. Shiota, Hiroshi Kido, K. Watanabe, K. Nagata and T. Toyoda :
Inhibition of the protease activity of influenza virus RNA polymerase PA subunit by viral matrix protein,
Microbiology and Immunology, Vol.47, No.7, 521-526, 2003.
(PubMed: 12953845)
105. Hiroshi Kido, Ping Cui, S. Sharmin, M. Shiota, Dengfu Yao, Chunxing Lin and Mihiro Yano :
Human mast cell chymase and 31 amino acid endothelin-1. New inflammatory mediators in cardiovascular diseases,
Cardiomyopathies and Heart Failure: Biomolecular, Infectious and Immune Mechanisms, 145-158, 2003.
106. H. Kitamura, Ping Cui, S. Sharmin, Mihiro Yano and Hiroshi Kido :
Binding of a new bioactive 31-amino-acid endothelin-1 to an endothelin ETB or ETB-like receptor in porcine lungs.,
European Journal of Pharmacology, Vol.465, No.1-2, 31-38, 2003.
(DOI: 10.1016/S0014-2999(03)01454-7,   PubMed: 12650830)
107. Hiroshi Kido, Yuushi Okumura, Hiroshi Yamada, 井手 美喜子, 水野 大 and 東 洋一郎 :
抗インフルエンザ作用を示す去痰剤の不思議,新たな薬理作用の機序,
アレルギー科, Vol.16, No.3, 232-239, 2003.
108. Y. Nakamura, M. Inoue, Yuushi Okumura, M. Shiota, M. Nishikawa, S. Arase and Hiroshi Kido :
Cloning, expression analysis, and tissue distribution of esp-1/testisin, a membrane-type serine protease from the rat.,
The Journal of Medical Investigation : JMI, Vol.50, No.1-2, 78-86, 2003.
(Tokushima University Institutional Repository: 110681,   PubMed: 12630572,   CiNii: 110002238062,   Elsevier: Scopus)
109. Hiroshi Kido, Ye Chen, Hiroshi Yamada and Yuushi Okumura :
インフルエンザウイルスの感染感受性をきめる個体のプロテアーゼ群とインフルエンザ脳症の発症機序,
Folia Pharmacologica Japonica, Vol.122, No.1, 45-53, 2003.
(DOI: 10.1254/fpj.122.45,   CiNii: 130000085997)
110. Dengfu Yao, Masamichi Kuwajima and Hiroshi Kido :
Pathologic mechanisms of influenza encephalitis with an abnormal expression of inflammatory cytokines and accumulation of mini-plasmin,
The Journal of Medical Investigation : JMI, Vol.50, No.1-2, 1-8, 2003.
(Tokushima University Institutional Repository: 110672,   PubMed: 12630563,   CiNii: 110001902031)
111. Hiroshi Kido, Yuushi Okumura, Hiroshi Yamada, 井手 美喜子 and 塩田 麻由美 :
肺サーファクタントはインフルエンザ感染に対する重要な生体防御物質の1つである.肺サーファクタントの作用とその分泌促進剤,
Journal of Japanese Medical Society for Biological Interface, Vol.34, No.1,2, 8-10, 2003.
(CiNii: 10013422611)
112. M. Sato, S. Yoshida, K. Iida, T. Tomosawa, Hiroshi Kido and M. Yamashita :
A novel influenza A virus activating enzyme from porcine lung: Purification and characterization,
Biological Chemistry, Vol.384, No.2, 219-227, 2003.
(DOI: 10.1515/BC.2003.024,   PubMed: 12675514)
113. Hiroshi Kido, Hiroshi Yamada, Yuushi Okumura, Mineyoshi Hiyoshi, Miwa Bando and Mihiro Yano :
インフルエンザウイルスの特性:増殖と感染のメカニズムー最新の知見をもとにー,
内科, Vol.90, 809-815, 2002.
114. Hiroshi Kido :
生体のウイルス感染感受性因子と近未来型感染予防法,
Antibiotics and Chemotherapy, Vol.18, No.7, 15, 2002.
115. M. Kihara, H. Kakegawa, Y. Matono, E. Murata, H. Tsuge, Hiroshi Kido and N. Kaunuma :
Chondroitin sulfate proteoglycan Is a potent enhancer in the processing of procathepsin L,
Biological Chemistry, Vol.383, No.12, 1925-1929, 2002.
(DOI: 10.1515/BC.2002.216,   PubMed: 12553729)
116. Hiroshi Kido, Yuushi Okumura, Mineyoshi Hiyoshi, Miwa Bando, 木下 盛敏 and 福田 陽司 :
ダイヤモンドDNAチップ「ジーンダイヤ 」の応用とチップを用いたプロテオミクス解析,
The Journal of the Institute of Electronics, Information and Communication Engineers, Vol.85, No.10, 725-727, 2002.
117. T. Towatari, M. Ide, K. Ohba, Y. Chiba, M. Murakami, M. Shiota, M. Kawachi, Hiroshi Yamada and Hiroshi Kido :
Identification of ectopic anionic trypsin I in rat lungs potentiating pneumotropic virus infectivity and increased enzyme level after virus infection,
European Journal of Biochemistry, Vol.269, No.10, 2613-2621, 2002.
(DOI: 10.1046/j.1432-1033.2002.02937.x,   PubMed: 12027901)
118. 西川 舞, Bing Yang, 井手 美喜子, Yuushi Okumura and Hiroshi Kido :
生体防御因子群の分泌を促進する塩酸アンブロキソールの抗インフルエンザ効果,,
Shikoku Acta Medica, Vol.58, No.3, 162-167, 2002.
(Tokushima University Institutional Repository: 110544)
119. Sharmin S., Shiota M., Murata E., Cui P., Kitamura H., Mihiro Yano and Hiroshi Kido :
A novel bioactive 31-amino acid endothelin-1 peptide stimulates eosinophil recruitment, and increases the level of eotaxin and IL-5,
Inflammation Research, Vol.51, No.4, 195-200, 2002.
(DOI: 10.1007/PL00000292,   PubMed: 12058957)
120. Hiroshi Kido, Yang Bing, 井手 美喜子, Yuushi Okumura and Hiroshi Yamada :
生体防御物質の気道内分泌を促進する塩酸アンブロキソールの抗インフルエンザ効果,
呼吸器 Neuws & Views, Vol.20, 16-18, 2002.
121. Hiroshi Kido, 唐渡 孝枝 and Hiroshi Yamada :
インフルエンザウイルスの感染性と感染憎悪を制御する生体内プロテアーゼとインヒビター,
Molecular Medicine, Vol.39, No.1, 48-53, 2002.
(CiNii: 40004990599)
122. Bing Yang, Deng Fu Yao, M. Ohuchi, M. Ide, Mihiro Yano, Yuushi Okumura and Hiroshi Kido :
Ambroxol suppresses influenza-virus proliferation in the mouse airway by incresing antiviral factor levels,
The European Respiratory Journal, Vol.19, No.5, 952-958, 2002.
(DOI: 10.1183/09031936.02.00253302,   PubMed: 12030738)
123. Masahiko Maegawa, Masaharu Kamada, Satoshi Yamamoto, Shuji Yamano, Minoru Irahara, Hiroshi Kido and Toshihiro Aono :
Involvement of carbohydrate molecules on zona pellucida in human fertilization,
Journal of Reproductive Immunology, Vol.53, No.1-2, 79-89, 2002.
(DOI: 10.1016/S0165-0378(01)00096-1,   PubMed: 11730906)
124. Shuji Kondo, Shoji Kagami, Hiroshi Kido, Strutz Frank, Muller A. Gerhard and Yasuhiro Kuroda :
Role of Mast Cell Tryptase in Renal Interstitial Fibrosis,
Journal of the American Society of Nephrology, Vol.12, No.8, 1668-1676, 2001.
(PubMed: 11461939,   Elsevier: Scopus)
125. Ping Cui, Kenji Tani, Hiroko Kitamura, Yuushi Okumura, Mihiro Yano, Daisuke Inui, Toshiaki Tamaki, Saburo Sone and Hiroshi Kido :
A novel bioactive 31-amino acid endothelin-1 is a potent chemotactic peptide for human neutrophils and monocytes,
Journal of Leukocyte Biology, Vol.70, No.2, 306-312, 2001.
(PubMed: 11493624)
126. K. Hara, M. Shiota, Hiroshi Kido, Y. Ohtsu and T. Toyoda :
Protease activity of influenza virus RNA polymerase PA subunit,
International Congress, Vol.1219, 479-485, 2001.
127. Wakabayashi H., Mihiro Yano, Tachikawa N., Oka S., Maeda M. and Hiroshi Kido :
Increased concentrations of 14-3-3ϵ,γ and ζ isoforms in cerebrospinal fluid ofAIDS patients with neuronal destruction,
Clinica Chimica Acta, Vol.312, No.1-2, 97-105, 2001.
(DOI: 10.1016/S0009-8981(01)00595-2,   PubMed: 11580914)
128. Hiroshi Kido and 鳥居 新平 :
生体防御物質の気道分泌を促進する去痰剤の抗インフルエンザ効果と今後の展望,特集 喘息長期管理"吸入ステロイド軸に成人·小児とも新ステージへ",
日経メディカル, Vol.30, No.11, 93-96, 2001.
129. Hiroshi Kido :
プロテアーゼとプロテアーゼインヒビターが決定する,インフルエンザウイルスの感染と防御,
第15回大学と科学公開シンポジウム組織委員会編"タンパク質分解の不思議", 105-119, 2001.
130. M. Murakami, T. Towatari, M. Ohuchi, M. Shiota, M. Akao, Yuushi Okumura, Marina A.A.Parry and Hiroshi Kido :
Mini-plasmin found in the epithelial cells of bronchioles triggers infection by broad-spectrum influenza A viruses and Sendai virus,
European Journal of Biochemistry, Vol.268, No.10, 2847-2855, 2001.
(DOI: 10.1046/j.1432-1327.2001.02166.x,   PubMed: 11358500)
131. Hiroshi Kido and Mihiro Yano :
シャペロン,プロテアソーム "基礎生化学実験法"タンパク質II 機能,
動態解析法, Vol.3, 61-69, 2001.
132. R.D. Kim, S. Sharmin, M. Inoue and Hiroshi Kido :
Cloning and Expression of Novel Mosaic Serine Proteases with and without a Transmembrane Domain from Human Lung,
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, Vol.1518, No.1-2, 204-209, 2001.
(DOI: 10.1016/S0167-4781(01)00184-1,   PubMed: 11267681)
133. Hiroshi Kido, Mihiro Yano, 河本 泰子 and 岡 夏生 :
プロテアソームの中の分子シャペロン,
BIO Clinica, Vol.16, No.4, 76-80, 2001.
134. N. Okishima, M. Yoshizumi, K. Tsuchiya, Ping Cui, H. Kitamura, T. Tamaki and Hiroshi Kido :
Determination of the Levels of Novel Bioactive 31-Amino-Acid Endothelins and Endothelins in Human Lungs,
Life Sciences, Vol.68, No.18, 2073-2080, 2001.
(DOI: 10.1016/S0024-3205(01)00998-5,   PubMed: 11324712)
135. K. Hara, M. Shiota, Hiroshi Kido, Y. Ohtsu, T. Kashiwagi, J. Iwahashi, N. Hamada, K. Mizoue, N. Tsumura, H. Kato and T. Toyoda :
Influenza Virus RNA Polymerase PA Subunit is a Novel Serine Protease with Ser 624 in the Active Site,
Genes to Cells, Vol.6, No.2, 87-97, 2001.
(DOI: 10.1046/j.1365-2443.2001.00399.x,   PubMed: 11260254)
136. Naoko Okishima, Masanori Yoshizumi, Koichiro Tsuchiya, Ping Cui, Hiroko Kitamura, Toshiaki Tamaki and Hiroshi Kido :
Determination of the levels of novel 31-amino acid endothelins and endothelins in human lungs.,
Life Sciences, Vol.68, No.18, 2073-2080, 2001.
137. Shuji Yoshikawa, Masaharu Kamada, Masahiko Maegawa, Satoshi Yamamoto, Minoru Irahara, Shuji Yamano, Toshihiro Aono, Hiroshi Kido and Samuel S Koide :
Hormonal Control of mRNA Expression of Immunoglobulin Binding Factor in Uterine Cervix,
Biochemical and Biophysical Research Communications, Vol.279, No.3, 898-903, 2000.
(DOI: 10.1006/bbrc.2000.4036,   PubMed: 11162446,   Elsevier: Scopus)
138. Hiroshi Kido :
インフルエンザウイルス感染と生体防御物質ー感染機序の最近の進歩ー,
高知県小児科医会報, No.11, 7-13, 2000.
139. Hiroshi Kido, 村上 明子, 赤尾 美代子 and 唐渡 孝枝 :
インフルエンザウイルス感染のメカニズムー基礎研究の進歩,
カレントテラピー, Vol.18, No.11, 1959-1965, 2000.
140. Hiroshi Kido, Mihiro Yano and 河本 泰子 :
分子シャペロンによるタンパク質の立体構造の管理とタンパク質分解,
神経難病の分子機構, 32-43, 2000.
141. Hiroshi Kido, 村上 明子, 川内 美樹 and 唐渡 孝枝 :
宿主側からみたインフルエンザウイルス感染のメカニズム,
Respiration & Circulation, Vol.48, No.11, 1105-1111, 2000.
142. Hiroshi Kido, 村上 明子, 楊 兵 and 唐渡 孝枝 :
ウイルス感染の制御因子,細胞性プロテアーゼとプロテアーゼインヒビター,
タンパク質分解:分子機構と細胞機能, 165-173, 2000.
143. Hiroshi Kido, 村上 明子, 楊 兵 and 唐渡 孝枝 :
インフルエンザ感染を制御する生体内プロテアーゼと気道内制御物質,
細胞工学, Vol.19, No.1, 33-38, 2000.
144. Y. Chen, M. Shiota, M. Ohuchi, T. Towatari, J. Tashiro, M. Murakami, Mihiro Yano, B. Yang and Hiroshi Kido :
Mast Cell Tryptase from Pig Lungs Triggers Infection by Pneumotropic Sendai and Influenza A Viruses (Purification and Characterizatiion,
European Journal of Biochemistry, Vol.267, No.11, 3189-3197, 2000.
(DOI: 10.1046/j.1432-1327.2000.01346.x,   PubMed: 10824103,   Elsevier: Scopus)
145. Hiroshi Kido :
インフルエンザ感染は克服できるかー分子生物学と酵素学からの挑戦,
細胞工学, Vol.19, No.1, 22-25, 2000.
(CiNii: 40004441056)
146. Mori H., Inoue M., Mihiro Yano, Wakabayashi H. and Hiroshi Kido :
14-3-3τAssociates with a Translational Control Factor FKBP12-Rapamycin-Associated Protein in T Cells after Stimulation by Pervanadate,
FEBS Letters, Vol.467, No.1, 61-64, 2000.
(DOI: 10.1016/S0014-5793(00)01126-1,   PubMed: 10664457,   Elsevier: Scopus)
147. Hiroshi Kido, 大内 正信 and 永武 毅 :
インフルエンザ20世紀の総括,
Pharma Medica, Vol.18, No.2, 159-169, 2000.
148. Kenji Tani, Fumitaka Ogushi, Hiroshi Kido, Tetsuya Kawano, Yuichi Kunori, Takashi Kamimura, Ping Cui and Saburo Sone :
Chymase is a potent chemoattractant for human monocytes and neutrophils,
Journal of Leukocyte Biology, Vol.67, No.4, 585-589, 2000.
(DOI: 10.1002/jlb.67.4.585,   PubMed: 10770293,   Elsevier: Scopus)
149. Masanori Yoshizumi, Daisuke Inui, Kazuyoshi Kirima, Koichiro Tsuchiya, Hitoshi Houchi, Mami Azuma, Hiroaki Yasuoka, Hiroshi Kido and Toshiaki Tamaki :
Comparison of the effects of endothelin-1,-2 and -3(1-31) on changes in [Ca2+]i in human coronary artery smooth muscle cells.,
The Japanese Journal of Pharmacology, Vol.81, 298-304, 1999.
150. Hiroaki Yasuoka, Masanori Yoshizumi, Daisuke Inui, Naoko Okishima, Hitoshi Houchi, Kazuyoshi Kirima, Shuzo Oshita, Hiroshi Kido and Toshiaki Tamaki :
Effect of endothelin-1 (1-31) on intracellular free calcium in cultured human mesangial cells.,
Life Sciences, Vol.65, No.22, PL267--272, 1999.
151. H. Yasuoka, M. Yoshizumi, D. Inui, N. Okishima*, H. Houchi, K. Kirima, S. Oshita, Hiroshi Kido and T. Tamaki :
Effect of Endothelin (1-31) on Intracellular Free Calcium in Cultured Human Mesangial Cells,
Life Sci., Vol.65, No.22, 267-272, 1999.
152. M. Inoue, M. Isobe, T. Itoyama and Hiroshi Kido :
Structural analysis of esp-1 gene (PRSS 21),,
Biochemical and Biophysical Research Communications, Vol.266, No.2, 564-568, 1999.
(DOI: 10.1006/bbrc.1999.1870,   PubMed: 10600542)
153. Mihiro Yano, Mori S. and Hiroshi Kido :
Intrinsic Nucleoside Diphosphate Kinase-like Activity is a Novel Function of the 20S Proteasome,
The Journal of Biological Chemistry, Vol.274, No.48, 34375-34382, 1999.
(DOI: 10.1074/jbc.274.48.34375,   PubMed: 10567415)
154. H. Takahashi, T. Iwata, Y. Kitagawa, R.H. Takahashi, Y. Sato, H. Wakabayashi, M. Takashima, Hiroshi Kido, Nagashima K., K. Kenney, C.J. Gibbs JR and T. Kurata :
Increased levels of ϵ and γIsoform-Specific Increase of 14-3-3 Proteins in Cerebrospinal Fluid of Patients with Creutzfeldt-Jakob Disease,
Clin. & Diag. Lab. Immunol., Vol.6, 983-985, 1999.
155. T. Iwata, K. Sakai, M. Hori, S. Uchida, T. Towatri and Hiroshi Kido :
Human Parathyroid Hormone (1-34) Transiently Increases the Excretion of Lysosomal Enzymes into Urine and the Size of Renal Lysosomes,
The Journal of Biochemistry, Vol.126, No.3, 485-493, 1999.
(PubMed: 10467163)
156. M. Yoshizumi, D. Inui, H. Houchi, H. Yasuoka, N. Okishima, Hiroshi Kido and T. Tamaki :
Comparison of the Effects of Endothelin-1,-2 and -3 (1-31) on Changes in [Ca2+]i in Human Coronary Artery Smooth Muscle Cells,
The Japanese Journal of Pharmacology, Vol.81, No.3, 298-304, 1999.
(DOI: 10.1254/jjp.81.298,   PubMed: 10622219)
157. T. Iwata, S. Uchida, M. Hori, K. Sakai, T. Towatari and Hiroshi Kido :
Human Parathyroid Hormone (1-34) Increases Urinary Excretion of Lysosomal Enzymes in Rats,
Life Sciences, Vol.65, No.17, 1725-1732, 1999.
(DOI: 10.1016/S0024-3205(99)00424-5,   PubMed: 10576551)
158. D. Inui, M. Yoshizumi, N. Okishima, H. Houchi, K. Tsuchiya, Hiroshi Kido and T. Tamaki :
Mechanism of Endothelin-1(1-31)-induced Calcium Signaling in Human Coronary Artery Smooth Muscle Cells.,
Am. J. Physiol., Vol.276, 1067-1072, 1999.
159. M. Hara, A. Matsumori, K. Ono, Hiroshi Kido, M.-W. Hwang, T. Miyamoto, A. Iwasaki, M. Okada, K. Nakatani and S. Sasayama :
Mast Cell Cause Apoptosis of Cardiomyocytes and Proliferation of Other Intramyocardial Cells In Vitro,
Circulation, Vol.100, No.13, 1443-1449, 1999.
160. Hiroshi Kido, M. Murakami, K. Oba, Y. Chen and T. Towatari :
Cellular Proteinases Trigger the Infectivity of the Influenza A and Sendai Viruses,
Molecules and Cells, Vol.9, No.3, 235-244, 1999.
(PubMed: 10420980,   Elsevier: Scopus)
161. 村上 明子, 唐渡 孝枝, 大場 久望子 and Hiroshi Kido :
インフルエンザウイルスの感染を制御する気道内酵素とインヒビター,
Shikoku Acta Medica, Vol.55, No.5, 174-179, 1999.
(Tokushima University Institutional Repository: 112153)
162. Hiroshi Kido, Y. Chen, M. Murakami, Y. Beppu and T. Towatari :
Cellular Proteinases and Viral Infection: Influenza Virus, Sendai Virus and HIV-1,
Proteases of Infectious Agents, 205-217, 1999.
163. 村上 明子, 唐渡 孝枝, 大場 久望子 and Hiroshi Kido :
インフルエンザウイルスの感染を制御する気道内酵素とインヒビター,
BIO Clinica, Vol.14, No.11, 79-84, 1999.
164. Hiroshi Kido, Y. Beppu, Y. Imamura, Y. Chen, M. Murakami, K. Oba and T. Towatari :
Human Mucus Protease Inhibitor and its Mutants are Novel Defensive Compounds against,
Biopolymers, Vol.51, 79-86, 1999.
165. Hiroshi Kido, 村上 明子, 大場 久望子 and 唐渡 孝枝 :
次世代のインフルエンザ感染症の治療を考える,
阿南医報, Vol.126, 10-16, 1999.
166. Okishima N., Hagiwara Y., Seito T., Mihiro Yano and Hiroshi Kido :
Specific Sandwich-type Enzyme Immunoassays for Smooth Muscle Constricting Novel 31-Amino Acid Endothelins,
Biochemical and Biophysical Research Communications, Vol.256, No.1, 1-5, 1999.
(DOI: 10.1006/bbrc.1999.0277,   PubMed: 10066413)
167. Hiroshi Kido, 村上 明子, 大場 久望子 and 唐渡 孝枝 :
インフルエンザウイルスとセンダイウイルス感染を制御する細胞性プロテアーゼとプロテアーゼインヒビター,
Antibiotics and Chemotherapy, Vol.15, No.2, 42-51, 1999.
168. Yuushi Okumura, Mihiro Yano, M. Murakami, T. Towatari and Hiroshi Kido :
The Extracellular Processing of HIV-1 Envelope Glycoprotein gp160 by Human Plasmin.,
FEBS Lett.,, Vol.442, 39-42, 1999.
169. M. Inoue, N. Kanbe, M. Kurosawa and Hiroshi Kido :
Cloning and Tissue Distribution of a Novel Serine Protease esp-1 from Human Eosinophils,
Biochemical and Biophysical Research Communications, Vol.252, No.2, 307-312, 1998.
(DOI: 10.1006/bbrc.1998.9645,   PubMed: 9826525)
170. M. Yoshizumi, S. Kim, S. Kagami, A. Hamaguchi, K. Tsuchiya, H. Houchi, H. Iwao, Hiroshi Kido and T. Tamaki :
Effect of Endothelin-1(1-31) on Extracellular Signal-regulated Kinase and Proliferation of Human Coronary Artery Smooth Muscle Cells,
British Journal of Pharmacology, Vol.125, No.5, 1019-1027, 1998.
(DOI: 10.1038/sj.bjp.0702141,   PubMed: 9846640)
171. F. Kishi, K. Minami, N. Okishima, M. Murakami, S. Mori, Mihiro Yano, Y. Niwa, Y. Nakaya and Hiroshi Kido :
Novel 31-Amino Acid-Length Endothelins Cause Constriction of Vascular Smooth Muscle,
Biochemical and Biophysical Research Communications, Vol.248, No.2, 387-390, 1998.
(DOI: 10.1006/bbrc.1998.8980,   PubMed: 9675146)
172. T. Towatari, T. Miyamura, A. Kondo, I. Kato, M. Inoue, Mihiro Yano and Hiroshi Kido :
The Structure of Asparagine-linked Oligosaccharide of Rat Liver Cathepsin L Reflect the Substrate Specificity of Lysosomal Alpha-Mannosidase,
European Journal of Biochemistry, Vol.256, No.1, 163-169, 1998.
(DOI: 10.1046/j.1432-1327.1998.2560163.x,   PubMed: 9746360)
173. H. Mori, M. Kamada, M. Maegawa, S. Yamamoto, T. Aono, S. Futaki, Mihiro Yano, Hiroshi Kido and S.S. Koide :
Enzymatic Activation of Immunoglobulin Binding Factor in Female Reproductive Tract,
Biochemical and Biophysical Research Communications, Vol.246, No.2, 409-413, 1998.
(DOI: 10.1006/bbrc.1998.8633,   PubMed: 9610373)
174. M. Abe, M. Kurosawa, O. Ishikawa, Y. Miyach and Hiroshi Kido :
Mast Cell Tryptase Increases not Only the Proliferation of Human Dermal Fibroblast but Also Type I Collagen Production,
Clin. & Exp. Allergy, Vol.28, 1509-1517, 1998.
175. Hiroshi Kido and 田代 真人 :
インフルエンザを,めぐるトピックス,
Pharma Medica, Vol.16, No.11, 91-99, 1998.
176. M. Yoshizumi, D. Inui, N. Okishima, H. Houchi, K. Tsuchiya, H. Wakabayashi, Hiroshi Kido and T. Tamaki :
Endothelin-1 (1-31), A Novel Vasoactive Peptide Increases [Ca2+ ]i in Human Coronary Artery Smooth Muscle Cells,
European Journal of Pharmacology, Vol.348, No.2-3, 305-309, 1998.
(DOI: 10.1016/S0014-2999(98)00158-7,   PubMed: 9652347)
177. 唐渡 孝枝 and Hiroshi Kido :
カテプシン,
生体の科学, Vol.49, No.5, 481-484, 1998.
178. Hiroshi Kido, A. Nakano, N. Okishima, H. Wakabayashi, F. Kishi, Y. Nakaya, M. Yoshizumi and T. Tamaki :
Human Chymase as the Enzyme Forming Novel Bioactive 31-Amino Acid Length Endothelins,
Biological Chemistry, Vol.379, No.7, 885-891, 1998.
(PubMed: 9705152)
179. Hiroshi Kido, 別府 良人, 村上 明子, 唐渡 孝枝 and 大場 久望子 :
ヒト粘液プロテアーゼインヒビターによるインフルエンザウイルスの感染抑制,
治療学, Vol.32, No.8, 1005-1009, 1998.
180. M. Hiromura, Mihiro Yano, H. Mori, M. Inoue and Hiroshi Kido :
Intrinsic ADP-ATP Exchange Activity is a Novel function of the Molecular Chaperone, Hsp70,
The Journal of Biological Chemistry, Vol.273, No.10, 5435-5438, 1998.
(DOI: 10.1074/jbc.273.10.5435,   PubMed: 9488662)
181. Masanori Yoshizumi, Daisuke Inui, Naoko Okishima, Hitoshi Houchi, Koichiro Tsuchiya, Hideki Wakabayashi, Hiroshi Kido and Toshiaki Tamaki :
Endothelin-1(1-31), a novel vasoactive peptide, increases [Ca2+]i in humen coronary artery smooth muscle cells.,
European Journal of Pharmacology, Vol.348, No.2-3, 305-309, 1998.
182. Masanori Yoshizumi, Shokei Kim, Shoji Kagami, Akinori Hamaguchi, Koichiro Tsuchiya, Hitoshi Houchi, Hiroshi Iwao, Hiroshi Kido and Toshiaki Tamaki :
Effect of endothelin-1(1-31)on extracellular signal-regulated kinase and proliferation of human coronary artery smooth muscle cells.,
British Journal of Pharmacology, Vol.125, No.5, 1019-1027, 1998.
183. Hiroshi Kido, Ayako Nakano, Naoko Okishima, Hideki Wakabayashi, Fumiko Kishi, Yutaka Nakaya, Masanori Yoshizumi and Toshiaki Tamaki :
Human chymase, an enzyme forming novel bioactive 31-amino acid length endothelins.,
The Journal of Biological Chemistry, Vol.379, 885-891, 1998.
184. T. Brinkmann, J. Schafers, L. Gurtler, Hiroshi Kido, Y. Niwa, N. Katunuma and H. Tschesche :
Inhibition of Tryptase TL2 from Human T4+lymphocytes and Inhibition of HIV-1 Replication in H9 Cells by Recombinant Aprotinin and Bikunin Homologues,
Journal of Protein Chemistry, Vol.16, No.6, 651-660, 1997.
(PubMed: 9263127)
185. Mihiro Yano, Mori S., Niwa Y., Inoue M. and Hiroshi Kido :
Intrinsic Nucleoside Diphosphate Kinase-like Activity as a Novel Function of 14-3-3 Proteins,
FEBS Letters, Vol.419, 244-248, 1997.
186. Hiroshi Kido, Y. Beppu and Y. Immamura :
Human Mucus Protease Inhibitor and its Mutants Prevent Infection by Influenza A and Sendai Viruses,
Medical Aspects of Proteases and Protease Inhibitors, 118-127, 1997.
187. A. Nakano, F. Kishi, K. Minami, H. Wakabayashi, Y. Nakaya and Hiroshi Kido :
Selective Conversion of Big Endothelins to Tracheal Smooth Muscle-Constricting 31-Amino Acid Length Endothelins by Chymase from Human Mast Cells,
The Journal of Immunology, Vol.159, No.4, 1987-1992, 1997.
(PubMed: 9257865)
188. T. Towatari, T. Miyamura, A. Kondo, I. Kato and Hiroshi Kido :
Structure Studies on the Carbohydrate Moiety of RatLliver Cathepsin L,
Proteolysis and Protein Turnover, 61-67, 1997.
189. Hiroshi Kido, Y. Beppu, K. Sakai and T. Towatari :
Protease Inhibitors and a Pulmonary Surfactant in Airway Fluid are Potential Defensive,
Proteolysis and Protein Turnover, 545-554, 1997.
190. Hiroshi Kido :
ウイルス感染を制御する細胞性プロテアーゼとプロテアーゼインヒビター(インフルエンザとエイズウイルスを中心として),
Tanpakushitsu Kakusan Koso, Vol.42, No.14, 2399-2407, 1997.
191. Hiroshi Kido, Y. Beppu, K. Sakai and T. Towatari :
Molecular Basis of Proteolytic Activation of Sendai Virus Infection and the Defensive,
Biol. Chem.,, Vol.378, 255-263, 1997.
192. Hiroshi Kido :
HIV-1 の標的細胞認識と感染機序,
HIV-1 感染による神経障害の診療マニュアル, 138-150, 1997.
193. Y. Beppu, Y. Imamura, M. Tashiro, T. Towatari, H. Ariga and Hiroshi Kido :
Human Mucus Protease Inhibitor in Airway Fluids Is a Potential Defensive Compound against Infection with Influenza A and Sendai Viruses,
The Journal of Biochemistry, Vol.121, No.2, 309-316, 1997.
(PubMed: 9089405)
194. Yuushi Okumura, H. Sato, M. Seiki and Hiroshi Kido :
Proteolytic Activation of the Precursor of Membrane Type 1 Matrix Metalloproteinase by Human Plasmin,
FEBS Letters, Vol.402, 181-184, 1997.
195. M. Tashiro, Y. Beppu, K. Sakai and Hiroshi Kido :
Inhibitory Effect of Pulmonary Surfactant on Sendai Virus Infection in Rat Lungs,
Arch. Virol., Vol.141, 1571-1577, 1996.
196. Hiroshi Kido, Y Niwa, Y Beppu and T Towatari :
Cellular Proteases Involved in The Pathogenicity of Enveloped Animal Virus, Human Immunodeficiency Virus, Influenza Virus A and Sendai Virus,
Advances in Enzyme Regulation, Vol.36, 325-347, 1996.
(DOI: 10.1016/0065-2571(95)00016-x,   PubMed: 8869754,   Elsevier: Scopus)
197. 滝沢 敬夫, 福地 義之助 and Hiroshi Kido :
呼吸器感染症と肺サーファクタント サーファクタントの基礎的作用と臨床への応用,
日経メディカル, Vol.12, 39-43, 1996.
198. Yuushi Okumura, A. Kudoh, M. Takashima, M. Inoue, K. Sakai and Hiroshi Kido :
Purification and Characterization of a Novel Isoform of Mast Cell Tryptase from Rat Tongue,
The Journal of Biochemistry, Vol.120, No.4, 856-864, 1996.
(PubMed: 8947853)
199. Hiroshi Kido :
プロテアーゼ阻害薬と感染症,
感染症, 158-159, 1996.
200. Niwa Y., Mihiro Yano, Futaki S., Yuushi Okumura and Hiroshi Kido :
T Cell Membrane Associated Serine Protease, Tryptase TL2, Binds Human Immunodeficiency Virus Type 1 gp120 and Cleaves The Third-Variable-Domain Loop of gp120. Neutralizing Antibodies of Human Immunodeficiency Virus Type I Inhibits Cleavage of gp120,
Eur. J. Biochem., Vol.237, 64-70, 1996.
201. Hiroshi Kido and 丹羽 保晴 :
AIDS ウイルスの感染性と複製に関与するT 細胞プロテアーゼ群,
Journal of Clinical and Experimental Medicine, Vol.176, No.1, 55-60, 1996.
202. Hiroshi Kido, T. Towatari, Y. Niwa, Yuushi Okumura and Y. Beppu :
Cellular Proteases Involved in the Pathogenicity of Human Immunodeficiency and Influenza Virus,
Advances in Experimental Medicine and Biology, Vol.389, 233-240, 1996.
203. Lihong Wang, Hideki Hayashi, Yasumasa Mitani, Kazuo Ishii, Tetsuo Ohnishi, Yasuharu Niwa, Hiroshi Kido and Yousuke Ebina :
Cloning of a cDNA encoding a 190-kDa insulin receptor substrate-1-like protein of simian COS cells.,
Biochemical and Biophysical Research Communications, Vol.216, No.1, 321-328, 1995.
204. L. Wang, H. Hayashi, Y. Mitani, K. Ishii, T. Ohnishi, Y. Niwa, Hiroshi Kido and Y. Ebina :
Cloning of a cDNA Encoding a 190-kDa Insulin Receptor Substrate-1-like Protein of Simian CO5 Cells,
Biochemical and Biophysical Research Communications, Vol.216, No.1, 321-328, 1995.
(PubMed: 7488107)
205. T. Ohshita and Hiroshi Kido :
Simple Preparation of Rat Brain Lysosomes and Their Proteolytic Properties,
Anal. Biochem., Vol.230, 41-47, 1995.
206. Hiroshi Kido and N. Katunuma :
Control of Tryptase and Chymase Activity by Protease Inhibitors,
Mast Cell Proteases in Immunology and Biology, Vol.11, 237-255, 1995.
207. Keiichi Kamoshita, Mayumi Shiota, Masafumi Sasaki, Yasuhiro Koga, Yuushi Okumura and Hiroshi Kido :
Calcium Requirement and Inhibitor Spectrum for Intracellular HIV Type 1 gp160 Processing in Cultured HeLa Cells and CD4+ Lymphocytes: Similarity to Those of Viral Envelope Glycoprotein Maturase,
The Journal of Biochemistry, Vol.117, No.6, 1244-1253, 1995.
208. Hiroshi Kido, 唐渡 孝枝, 別府 良人, 坂井 堅太郎 and 山口 晋史 :
トリプターゼクララとインフルエンザウイルス感染,
The Lung, Vol.3, No.2, 74-78, 1995.
209. N. Shimizu, M. Kobayashi, Hui-Yu Liu, Hiroshi Kido and H. Hoshino :
Detection of Tryptase TL2 and CD26 Antigen in Brain-Derived Cells Non-Permissive to T-Cell-Line-Tropic Human Immunodeficiency Virus Type 1,
FEBS Lett.,, Vol.358, 48-52, 1995.
210. T. Yamaguchi, M. Fukase, T. Sugimoto, Hiroshi Kido and K. Chihara :
Purification of Meprin from Human Kidney and its Role in Parathyroid Hormone Degradation,
Biol. Chem. Hoppe-Seyler, Vol.375, 821-824, 1994.
211. T. Brinkmann, J. Schafers, L. Gurtler, Hiroshi Kido, Y. Niwa, N. Katunuma and H. Tschesche :
Inhibition of Tryptase TL2 from Human T4+ lymphocytes and In Vitro Inhibition of HIV-1 Replication in H9 Cells by Recombinant Aprotinin and Bikunin Variants,
Journal AIDS-Forschung (AIFO),, Vol.9, 602, 1994.
212. T. Ohshita and Hiroshi Kido :
Involvement of a Cystatin-a-Sensitive Cysteine Proteinase in the Degradation of Native L-lactate Dehydrogenase and Serum Albumin by Rat Liver or Kidney Lysosomes,
Eur. J. Biochem.,, Vol.225, 781-786, 1994.
213. M. Inoue, T. Hoshino, T. Fukuma, Y. Niwa and Hiroshi Kido :
Close Co-localization of CD4 and a Serine Esterase Tryptase TL2 on the Cell-surface of Human Monocytoid and CD4+ lymphoid Cells,
Biochemical and Biophysical Research Communications, Vol.201, No.3, 1390-1395, 1994.
(DOI: 10.1006/bbrc.1994.1857,   PubMed: 7912927)
214. T. Yamaguchi, M. Fukase, Hiroshi Kido, T. Sugimoto, N. Katunuma and K. Chihara :
Meprin is Predominantly Involved in Parathyroid Hormone Degradation by the Microvillar Membranes of Rat Kidney,
Life Sciences, Vol.54, No.5, 381-386, 1994.
215. Y. Matsunaga, Hiroshi Kido, K. Kawaji, K. Kamoshita, N. Katunuma and T. Ogura :
Inhibitors of Chymotrypsin-like Proteases Inhibit Eosinophil Peroxidase Release from Activated Human Eosinophils,
Arch. Biochem. Biophys., Vol.312, No.1, 67-74, 1994.
216. S. Iwata, A.C. Schmidt, K. Titani, M. Suzuki, Hiroshi Kido, B. Gotoh, M. Hamaguchi and Y. Nagai :
Assignment of Disulfide Bridges in the Fusion Glycoprotein of Sendai Virus,
Journal of Virology, Vol.68, No.5, 3200-3206, 1994.
(PubMed: 8151783)
217. Hiroshi Kido :
インフルエンザの感染機序:気管支粘膜上皮細胞のプロテアーゼと制御因子,
Molecular Medicine (特集,造血器腫瘍の発症とシグナル伝達), Vol.31, No.9, 1047-1049, 1994.
218. K. Sakai, T. Kohri, M. Tashiro, Y. Kishino and Hiroshi Kido :
Sendai Virus Infection Changes the Subcellular Localization of Tryptase Clara in Rat Bronchiolar Epithelial Cells,
Eur. Respir. J., Vol.7, 686-692, 1994.
219. Hiroshi Kido, 丹羽 保晴 and 井上 雅広 :
HIV の外膜蛋白質 gp120 のV3領域と特異的に結合するトリプターゼ TL2,
Medical Immunology, Vol.27, No.4, 351-359, 1994.
220. M. Takeda, S. Tanaka, Hiroshi Kido, S. Daikoku, M. Oka, K. Sakai and N. Katunuma :
Chromaffin Cells Express Alzheimer Amyloid Precursor Protien in the Same Manner as Brain Cells,
Neuroscience Letters, Vol.168, 57-60, 1994.
221. Hiroshi Kido :
ウイルス感染と細胞内プロテアーゼ ーインフルエンザウイルス,エイズウイルスを中心としてー,
Seikagaku, Vol.66, No.8, 1130-1134, 1994.
222. S Takada, Hiroshi Kido, A Fukutomi, T Mori and K Koike :
Interaction of Hepatitis B Virus X Protein with a Serine Protease, Tryptase TL2, as an Inhibitor,
Oncogene, Vol.9, No.2, 341-348, 1994.
(PubMed: 8290248)
223. Hiroshi Kido, K. Kamoshita and N. Katunuma :
A Processing Protease for gp160 HIV-1 Envelope Glycoprotein Precursor in Human T4+ lymphocytes,
Biological Functions of Proteases and Inhibitors, 199-212, 1993.
224. Hiroshi Kido :
Cellular processing proteases for the envelope glycoprotein precursors of human immunodeficiency virus-1 and of influenza and parainfluenza viruses,
Proteolysis and Protein Turnover, 209-217, 1993.
225. Y. Matsunaga, T. Saibara, Hiroshi Kido and N. Katunuma :
Participation of cathepsin B in Processing of antigen Presentation to MHC-Class II,
FEBS Letters, Vol.324, No.3, 325-330, 1993.
226. Y. Sukenaga, Hiroshi Kido, A. Neki, M. Enomoto, K. Ishida, K. Takagi and N. Katunuma :
Purification and Molecular Cloning of Chymase from Human Tonsils,
FEBS Letters, Vol.323, No.1,2, 119-122, 1993.
227. Hiroshi Kido :
セリンプロテアーゼ,
生物化学実験法:蛋白質分解酵素I, Vol.30, 5-38, 1993.
228. M. Tashiro, M. Takeda, S. Tanaka, N. Nishimura, M. Takenaka and Hiroshi Kido :
Antibody Against the Carboxyl Terminus of the F2 Subunit of Sendai Virus Fusion Glycoprotein Inhibits Proteolytic Activation,
Virology, Vol.194, 882-885, 1993.
229. Hiroshi Kido :
肥満細胞とプロテアーゼの多様性およびその生理的意義,肥満細胞の新しい側面とアレルギー性疾患治療,
Excerpta Medica, 25-41, 1993.
230. Hiroshi Kido, K. Sakai, Y. Kishino and M. Tashiro :
Pulmonary Surfactant is A Potential Endogenous Inhibitor of Proteolytic Activation of Sendai Virus and Influenza A Virus,
FEBS Lett.,, Vol.322, No.2, 115-119, 1993.
231. 川地 康司, 松永 洋一, Hiroshi Kido and 小倉 剛 :
活性化好酸球からの Eosinoophil Peroxidase 放出におけるキモトリプシン型プロテアーゼの関与,
Japanese Journal of Allergology, Vol.42, No.10, 1591-1599, 1993.
232. Hiroshi Kido, Keiichi Kamoshita, Akiko Fukutomi and Nobuhiko Katunuma :
Processing Protease for gp160 Human Immunodeficiency Virus Type I Envelope Glycoprotein Precursor in Human T4+ lymphocytes: Purification and Characterization,
The Journal of Biological Chemistry, Vol.268, No.18, 13406-13413, 1993.
(PubMed: 8099909)
233. Hideki Hayashi, Yasuhiko Nishioka, Seika Kamohara, Fumihiko Kanai, Kazuo Ishii, Yasuhisa Fukui, Futoshi Shabisaki, Tadaomi Takenawa, Hiroshi Kido, Nobuhiko Katsunuma and Yousuke Ebina :
The alpha-Type 85-kDa subunit of Phosphatidylinositol 3-Kinase is Phosphorylatedat Tyrosines 368, 580, and 607 by the Insulin Receptor,
The Journal of Biological Chemistry, Vol.268, No.10, 7107-7117, 1993.
234. Hiroshi Kido :
ウイルス感染とプロテアーゼ ーエイズウイルス,インフルエンザウイルスの感染と増殖に関与するプロテアーゼー,
現代化学, Vol.22, 214-221, 1993.
235. Hiroshi Kido, M. Takeda, H. Wakabayashi, S. Tanaka, N. Nishimura, M. Takenaka and M. Okada :
Purification of a Trypsin-Type Protease from Human Umbilical Vein Endothelial Cells, That is Highly Sensitive to The Kunitz Inhibitor Domain Peptide of Alzheimer's Disease Amyloid Protein Precursor,
Gerontology, Vol.39, 30-37, 1993.
236. Hiroshi Kido :
アレルギー性炎症とプロテアーゼ,
喘息, Vol.6, No.4, 69-75, 1993.
237. Toru Yamaguchi, Hiroshi Kido, Riko Kitazawa, Sohei Kitazawa, Masaaki Fukase and Nobuhiko Katunuma :
A Membrane-Bound Metallo-Endopeptidase from Rat Kidney: Its Immunological Characterization,,
The Journal of Biochemistry, Vol.113, No.3, 299-303, 1993.
(PubMed: 8486602)
238. Hiroshi Kido :
Tーリンパ球膜局在新プロテアーゼの発見とそのAIDS ウイルス受容体としての作用機序の解明,
細胞科学, Vol.4, 97-108, 1993.
239. H. Hayashi, Y. Nishioka, S. Kamohara, F. Kanai, K. Ishii, Y. Fukui, F. Shibasaki, T. Takenawa, Hiroshi Kido, N. Katunuma and Y. Ebina :
The a-Type 85-kDa Subunit of Phosphatidylinositol 3-Kinase is Phosphorylated at Tyrosine 368, 580, and 607 by The Insulin Receptor,
The Journal of Biological Chemistry, Vol.268, No.10, 7107-7117, 1993.
(PubMed: 8385099)
240. Hiroshi Kido :
プロテアーゼインヒビター,
呼吸, Vol.12, No.8, 1028-1035, 1993.
241. K Sakai, Y Kawaguchi, Y Kishino and Hiroshi Kido :
Electron Immunohistochemical Localization in Rat Bronchiolar Epithelial Cells of Tryptase Clara which Determines The Pneumotropism and Pathogenicity of Sendai Virus and Influenza Virus,
The Journal of Histochemistry and Cytochemistry, Vol.41, No.1, 89-93, 1993.
(DOI: 10.1177/41.1.8380186,   PubMed: 8380186,   Elsevier: Scopus)
242. Hiroshi Kido :
肥満細胞とプロテアーゼ,
プロテアーゼとそのインヒビター ---生理的意義および病態との関連, 217-226, 1992.
243. Hiroshi Kido :
エイズウイルス感染と細胞内プロテアーゼ,
BIO medica, Vol.7, No.6, 19-25, 1992.
244. M. Tashiro, Y. Yokogoshi, K. Tobita, J.T. Seto, R. Rott and Hiroshi Kido :
Tryptase Clara, An Activating Protease for Sendai Virus in Rat Lungs, is Involved in Pneumopathogenicity,
Journal of Virology, Vol.66, No.12, 7211-7216, 1992.
(PubMed: 1331518)
245. Hiroshi Kido :
HIV (侵入に関与する細胞因子),
Mebio, Vol.9, No.6, 32-40, 1992.
246. Hiroshi Kido, Yutaka Yokogoshi, Kentaro Sakai, Masato Tashiro, Yasuo Kishino, Aiko Fukutomi and Nobuhiko Katunuma :
Isolation and Characterization of A Novel Trypsin-like Protease Found in Rat Bronchiolar Epithelial Clara Cells: A Possible Activator of The Viral Fusion Glycoprotein,
The Journal of Biological Chemistry, Vol.267, No.19, 13573-13579, 1992.
(PubMed: 1618859,   Elsevier: Scopus)
247. Hiroshi Kido and 勝沼 信彦 :
AIDSウイルス感染に関与する新しい細胞膜局在セリンプロテアーゼ -AIDSウイルスの新しいレセプターの可能性-,
Journal of Clinical and Experimental Medicine, Vol.162, 255-256, 1992.
248. Hiroshi Kido and N. Katunuma :
Biomodulators of Glucocorticoid: Amplifiers and Suppressors of Glucocorticoid Action,
Proceedings of The 1st International Congress on "Vitamins and Biofactors in Life Science", 279-282, 1992.
249. Hiroshi Kido, 福富 愛子, 鴨下 恵一 and 勝沼 信彦 :
エイズウイルス感染におけるヒトTリンパ球のプロテアーゼ群の役割,
Japanese Journal of Inflammation, Vol.12, No.4, 319-326, 1992.
250. T. Yamaguchi, Hiroshi Kido and N. Katunuma :
A Membrane-bound Metallo-endopeptidase from Rat Kidney:Characteristics of Its Hydrolysis of Peptide Hormones and Neuropeptides,
Eur. J. Biochem., Vol.204, 547-552, 1992.
251. Hiroshi Kido :
HIV-1 レセプター,
Immunology Frontier, Vol.4, 18-28, 1991.
252. Hiroshi Kido, A. Fukutomi and N. Katunuma :
A Novel Membrane-bound Serine Esterase in Human T4+ lymphocytes is A Binding Protein of Envelope Glycoprotein gp120 of HIV-1,
Biomedica Biochimica Acta, Vol.50, No.4-6, 781-789, 1991.
(PubMed: 1686971)
253. Hiroshi Kido :
ウイルス感染における宿主細胞プロテアーゼの役割,
Cell Science, Vol.7, No.12, 48-58, 1991.
254. R. Sharma, Hiroshi Kido and N. Katunuma :
H-7 Reduces The Nuclear Binding of [3H]Dexamethasone in Rat Liver Slice But Does Not Affect The Phosphorylation of Glucocorticoid Receptor,
Biochem. Med. Metabol. Biol., Vol.46, 246-254, 1991.
255. 唐渡 孝枝 and Hiroshi Kido :
カテプシンL,
検査と技術, Vol.19, No.11, 979-981, 1991.
256. T. Yamaguchi, Hiroshi Kido, M. Fukase, T. Fujita and N. Katunuma :
A Membrane-bound Metallo-endopeptidase from Rat Kidney Hydrolyzing Parathyroid Hormone: Purification and Characterization,
Eur. J. Biochem., Vol.200, No.2, 563-571, 1991.
257. 勝沼 信彦 and Hiroshi Kido :
Tリンパ球膜の新セリンプロテアーゼ,
Experimental Medicine, Vol.9, No.6, 98-101, 1991.
258. Hiroshi Kido, A. Fukutomi and N. Katunuma :
Tryptase TL2 in The Membrane of Human T4+ lymphocytes is A Novel Binding Protein of The V3 Domain of HIV-1 Envelope Glycoprotein gp120,
FEBS Letters, Vol.286, No.1,2, 233-236, 1991.
259. N. Katunuma and Hiroshi Kido :
Recent Advances in Research on Tryptases and Endogenous Tryptase Inhibitors,
Monogr. Allergy: Neutral Proteases of Mast Cells, Vol.27, 51-66, 1990.
260. 勝沼 信彦 and Hiroshi Kido :
新しいbioreactant としての細胞性セリンプロテアーゼと内在性インヒビター,
Seikagaku, Vol.62, No.1, 18-31, 1990.
261. Hiroshi Kido, A. Fukutomi, J. Schilling, Y. Wang, B. Cordell and N. Katunuma :
Protease-specificity of Kunitz Inhibitor Domain of Alzheimer's Disease Amyloid Protein Precursor,
Biochemical and Biophysical Research Communications, Vol.167, No.2, 716-721, 1990.
(PubMed: 1969731)
262. Hiroshi Kido and 勝沼 信彦 :
腸内最近由来物質のグルココルチコイド修飾作用,
腸内フローラと生体ホメオスタシス(光岡知足 編), 99, 1989.
263. Hiroshi Kido and 勝沼 信彦 :
セリンプロテアーゼとアレルギー炎症の成立機序,
肥満細胞·生理と病理(黒沢元博 編), 167-179, 1989.
264. Hiroshi Kido and 勝沼 信彦 :
酵素に特異的なセリンプロテアーゼインヒビター —特異的基質のホウ酸誘導体—,
生体の科学, Vol.40, No.4, 333-334, 1989.
265. Hiroshi Kido and N. Katunuma :
Biological Functions of Chymase and Tryptase and their Inhibitors in Rat Mast Cells,
Intracellular Proteolysis: Mechanisms and Regulations, 109-119, 1989.
266. Hiroshi Kido and 勝沼 信彦 :
バイオモジュレーターとしての細胞内Kunitz 型インヒビター —トリプスタチンを中心としてー,
細胞工学, Vol.7, No.11, 851-857, 1988.
267. Hiroshi Kido and 勝沼 信彦 :
肥満細胞セリン·プロテアーゼとアレルギー炎症の成立機序,
Metabolism and Disease, Vol.25, 187-192, 1988.
268. Hiroshi Kido and 勝沼 信彦 :
アレルギーとプロテアーゼ,プロテアーゼインヒビター,
最新医学, Vol.43, No.4, 770-775, 1988.
269. N. Fukusen, Hiroshi Kido, Y. Kato, K. Ishidoh and N. Katunuma :
Diacylglycerols Enhance the Anti-tumor Effect of Glucocorticoid on L5178Y Lymphoblasts in Vivo,
Japanese Journal of Cancer Research, Vol.80, No.10, 963-967, 1988.
(PubMed: 2559070)
270. T. Hattori, A. Koito, K. Takatsuki, Hiroshi Kido and N. Katunuma :
Involvement of Tryptase-related Cellular Protease(s) in Human Immunodeficiency Virus Type 1 Infection,
FEBS Letters, Vol.248, No.1,, 48-52, 1988.
271. N. Katunuma and Hiroshi Kido :
Biological Functions of Serine Proteases in Mast Cells in Allergic Inflammation,
Journal of Cellular Biochemistry, Vol.38, No.4, 291-301, 1988.
(DOI: 10.1002/jcb.240380408,   PubMed: 2467915,   Elsevier: Scopus)
272. Hiroshi Kido, Y. Yokogoshi and N. Katunuma :
Kunitz-type Protease Inhibitor Found in Rat Mast Cell: Purification, Properties and Amino Acid Sequence,
The Journal of Biological Chemistry, Vol.263, No.34, 18104-18108, 1988.
(PubMed: 3263966)
273. N. Katunuma, Y. Kato and Hiroshi Kido :
Studies on Biomodulators of Glucocorticoid Action: Amplifiers and Suppressors of Glucocorticoid Action,
Advances in Enzyme Regulation, Vol.27, 277-286, 1988.
(DOI: 10.1016/0065-2571(88)90021-0,   Elsevier: Scopus)
274. Yasuhisa Kato, Hiroshi Kido, Naomi Fukusen and Nobuhiko Katunuma :
Peptide Boronic Acids, Substrate Analogs, Inhibit Chymase, and Histamine Release from Rat Mast Cells,
The Journal of Biochemistry, Vol.103, No.5, 5, 1988.
(PubMed: 2460436)
275. Hiroshi Kido, N. Fukusen and N. Katunuma :
Antibodies and Inhibitions of Chymase are Incorporated into Mast Cell Granules and Inhibit Histamine Release,
Biol. Chem. Hoppe-Seyler, Vol.369, 95-100, 1988.
276. Hiroshi Kido, N. Fukusen and N. Katunuma :
Epidermal Growth Factor as a New Regulator of Induction of Tyrosine Aminotransferase and Tryptophan Oxygenase by Glucocorticoid,
FEBS Letters, Vol.223, No.2, 223-226, 1987.
277. Hiroshi Kido, N. Fukusen and N. Katunuma :
Tumor-promoting Phorbol Ester Amplifies the Inductions of Tyrosine Aminotransferase and Ornithine Decarboxylase by Glucocorticoid,
Biochemistry, Vol.26, No.8, 2349-2353, 1987.
278. Hiroshi Kido, N. Fukusen and N. Katunuma :
Inhibition by 1-(5-Isoguinolinesulfonyl)-2-Methyl-piperazine, an Inhibitor of Protein Kinase C, of Enzyme Induction by Glucocorticoid and of Nuclear Translocation of Glucocorticoid-Receptor Complexes,
Bichem. Biophys. Res. Commun., Vol.144, No.1, 152-159, 1987.
279. N. Katunuma and Hiroshi Kido :
Studies on Biomodulators of Glucocorticoid Actions: The Nature and the Modes of Actions of Glucocorticoid Potency Amplifiers,
Advances in Enzyme Regulation, Vol.26, 191-208, 1987.
(DOI: 10.1016/0065-2571(87)90014-8,   PubMed: 2890279,   Elsevier: Scopus)
280. N. Fukusen, Y. Kato, Hiroshi Kido and N. Katunuma :
Kinetic Studies on the Inhibitions of Mast Cell Chymase by Natural Serine Proteae Inhibitors. Indications for Potential Biological Functions of these Inhibitors,
Biochem. Med. Metab. Biol., Vol.38, 165-169, 1987.
281. 勝沼 信彦 and Hiroshi Kido :
IgE-Mast cell 関与のアレルギー炎症成立機序と顆粒局在Serine protease群の役割,
財団法人 日本応用酵素協会, No.21, 11-21, 1986.
282. Hiroshi Kido, N. Fukusen, K. Ishidoh and N. Katunuma :
Diacylglycerol Amplified the Induction in Vivo of Tyrosine Aminotransferase and Ornithine Decarboxylase by Glucocorticoid,
Biochemical and Biophysical Research Communications, Vol.138, No.1, 275-282, 1986.
(PubMed: 2874800)
283. Hiroshi Kido, K. Izumi, H. Otsuka, N. Fukusen, Y. Kato and N. Katunuma :
A Chymotrypsin-type Serine Protease in Rat Basophilic Leukemia Cells: Evidence for its Immunological Identity with Atypical Mast Cell Protease,
The Journal of Immunology, Vol.136, No.3, 1061-1065, 1986.
(PubMed: 2416825)
284. N. Katunuma, N. Fukusen and Hiroshi Kido :
Biological Functions of Serine Proteases in the Granules of Rat Mast Cells,
Advances in Enzyme Regulation, Vol.25, 241-255, 1986.
(DOI: 10.1016/0065-2571(86)90017-8,   PubMed: 3544704,   Elsevier: Scopus)
285. Hiroshi Kido, N. Fukusen, N. Katunum, T. Morita and S. Iwanaga :
Tryptase from Rat Mast Cells Converts Bovine Prothrombin to Thrombin,
Biochemical and Biophysical Research Communications, Vol.132, No.2, 613-619, 1985.
(PubMed: 3904753)
286. Hiroshi Kido, N. Fukusen and N. Katunuma :
Antibody and Inhibitor of Chymase Inhibit Histamine Release in Immunoglobulin E-Activated Mast Cells,
Biochemistry International, Vol.10, No.6, 863-871, 1985.
(PubMed: 2412558)
287. Hiroshi Kido, N. Fukusen and N. Katunuma :
Chymotrypsin-type and Trypsin-type Serine Protease in Rat Mast Cells: Properties and Functions,
Arch. Biochem. Biophys, Vol.239, No.2, 436-443, 1985.
288. N. Fukusen, Hiroshi Kido and N. Katunuma :
Inhibition of Chymase Activity by Phosphoglycerides,
Arch. Biochem. Biophys., Vol.237, No.1, 118-123, 1985.
289. Hiroshi Kido, N. Fukusen and N. Katunuma :
Inhibition of Chymase Activity by Long Ghain Fatty Acids,
Arch. Biochem. Biophys., Vol.230, No.2, 610-615, 1984.
290. Hiroshi Kido, N. Fukusen and N. Katunuma :
A Simple Method for Purification of Chymase from Rat Tongue and Rat Peritoneal Cells,
Anal. Biochem., Vol.137, 449-453, 1984.
291. Hiroshi Kido :
Purification and Structure of a New Nucleotide from Proteus Mirabilis that Amplifies Induction of Tyrosine Aminotransferase by Glucocorticoid,
Biochemical and Biophysical Research Communications, Vol.86, No.2, 3258-3261, 1979.
292. Hiroshi Kido :
Amplification of Growth Inhibition by Glucocorticoid on L5178Y and L1210 Lymphoblasts in Vivo,
Cancer Research, Vol.39, 3258-3261, 1979.
293. Hiroshi Kido :
Amplification of the Cytotoxic Action of Glucocorticoid in Cultured L5178Y Lymphoblasts,
Cancer Research, Vol.38, 3100-3103, 1978.
294. Hiroshi Kido :
A New Factor from Enteric Bacteria of Rats Amplifying Induction of Liver Enzyme by Glucocorticoid,
European Journal of Biochemistry, Vol.78, 541-546, 1977.
295. Hiroshi Kido :
Establishment of a Clonal Strain of Hepatoma Cells Derived fromMorris Hepatoma 8999,
Gann : Japanese Journal of Cancer Research, Vol.68, No.5, 691-697, 1977.

Academic Paper (Unrefereed Paper):

1. Kenta Horimukai, Kumiko Morita, Masami Narita, Mai Kondo, Hiroshi Kitazawa, Makoto Nozaki, Yukiko Shigematsu, Kazue Yoshida, Hironori Niizeki, Ken-Ichiro Motomura, Haruhiko Sago, Tetsuya Takimoto, Eisuke Inoue, Norio Kamemura, Hiroshi Kido, Junzo Hisatsune, Motoyuki Sugai, Hiroyuki Murota, Ichiro Katayama, Takashi Sasaki, Masayuki Amagai, Hideaki Morita, Akio Matsuda, Kenji Matsumoto, Hirohisa Saito and Yukihiro Ohya :
Application of moisturizer to neonates prevents development of atopic dermatitis.,
The Journal of Allergy and Clinical Immunology, Vol.134, No.4, 824-830.e6, 2014.
(DOI: 10.1016/j.jaci.2014.07.060,   PubMed: 25282564)
2. Hiroshi Kido, Norio Kamemura, 窪田 賢司 and 鈴木 宏一 :
高性能タンパクチップの臨床応用ー減感作療法やアレルギー・アトピーの発症予防への応用ー,
日本ラテックスアレルギー研究会会誌, Vol.18, No.2, 10-15, 2014.
3. Junji Chida and Hiroshi Kido :
Extraction and quantification of adenosine triphosphate in mammalian tissues and cells.,
Methods in Molecular Biology, Vol.1098, 21-32, 2014.
(DOI: 10.1007/978-1-62703-718-1_2,   PubMed: 24166365,   Elsevier: Scopus)
4. Hiroshi Kido and Junji Chida :
Pathogenesis of influenza-associated encephalopathy, --- CPT2 SNP as a phathogenetic risk factor ---,
Journal of Clinical and Experimental Medicine, Vol.241, No.1, 23-28, 2012.
(CiNii: 40019211587)
5. Hiroshi Kido, Dai Mizuno, Tunetomo Takei and Wakako Sihihara :
New effective nasal immunization of influenza vaccine by a natural mucosal adjuvant from the lung and its synthetic compound.,
Options for the Control of Influenza VI, 616-618, 2008.

Academic Letter:

1. Norio Kamemura, Norio Kawamoto, Ryosuke Nakamura, Reiko Teshima, Toshiyuki Fukao and Hiroshi Kido :
Low-affinity allergen-specific IgE in cord blood and affinity maturation after birth.,
The Journal of Allergy and Clinical Immunology, Vol.133, No.3, 904-5.e6, 2013.
(DOI: 10.1016/j.jaci.2013.09.034,   PubMed: 24231285)
2. Hideaki Morita, Ichiro Nomura, Kanami Orihara, Koichi Yoshida, Akira Akasawa, Hiroshi Tachimoto, Yoshikazu Ohtsuka, Yoshiyuki Namai, Masaki Futamura, Tetsuo Shoda, Akio Matsuda, Norio Kamemura, Hiroshi Kido, Takao Takahashi, Yukihiro Ohya, Hirohisa Saito and Kenji Matsumoto :
Antigen-specific T-cell responses in patients with non-IgE-mediated gastrointestinal food allergy are predominantly skewed to T(H)2.,
The Journal of Allergy and Clinical Immunology, Vol.131, No.2, 590-592, 2012.
(DOI: 10.1016/j.jaci.2012.09.005,   PubMed: 23083674)
3. Hiroshi Kido, Dengbing Yao, Junji Chida, Youssouf Cisse and Yao Min :
Pathogenesis of influenza-associated encephalopathy: disorder of fatty acid metabolism in mitochondria and increased membrane permeability in endothelial cells,
The Medical Frontline, Vol.65, No.1, 52-60, 2010.
(CiNii: 40016963116)
4. Hiroshi Kido, Dai Mizuno and Tunetomo Takei :
肺サーファクタントを基盤にした経鼻インフルエンザワクチン開発,
Journal of Japanese Medical Society for Lung Surfactant and Biological Interface, Vol.40, 110-114, 2009.
(CiNii: 10025615556)
5. Tunetomo Takei, Hiroshi Kido and 千田 勝一 :
SP-BとSP-Cの構造および機能,
Journal of Japanese Medical Society for Lung Surfactant and Biological Interface, Vol.40, No.0, 75-81, 2009.
(CiNii: 10025615465)
6. Hiroshi Kido :
インフルエンザとマクロライド,
呼吸器科, Vol.16, No.5, 393-399, 2009.
7. Hiroshi Kido :
インフルエンザウイルス感染症に効果的なマクロライドの粘膜粘液,
診断と新薬, Vol.46, No.11, 1135-1172, 2009.
8. Hiroshi Kido, 多田 仁美, 澤淵 貴子, Kouichi Suzuki and Norio Kamemura :
アレルゲン同定法の近未来展望,
アレルギー臨床, Vol.29, No.12, 49-53, 2009.
9. Hiroshi Kido :
インフルエンザ重傷化のメカニズム示す(第57回日本化学療法学会),
Medical Tribun, Vol.42, No.29, 34, 2009.

Review, Commentary:

1. Junji Chida, Hiroshi Kido and Suehiro Sakaguchi :
宿主因子を標的にした新たなインフルエンザ治療の試み,
BIO Clinica, Vol.256, No.33, 52-55, Feb. 2018.
2. Hiroshi Kido :
酵素タンパク質分解の促進と熱変性が引き起こす感染重症化に伴うインフルエンザ脳症の病態医科学,
細胞工学, Vol.35, No.2, 158-163, Jan. 2016.
3. Hiroshi Kido :
インフルエンザ感染の重症化機序解明と新規治療法の開発,
感染症, Vol.46, No.1, 13-15, Jan. 2016.
4. Hiroshi Kido and Mayumi Sugimoto :
Clinical application of a highly sensitive allergen microarray which can monitor immune response by immunoglobulin class switching.,
Japanese Journal of Allergology, Vol.65, No.6, 764-769, 2016.
(DOI: 10.15036/arerugi.65.764,   PubMed: 27439579,   CiNii: 130005166055)
5. Hiroshi Kido, Mayumi Sugimoto, Norio Kamemura, 窪田 賢司 and Kouichi Suzuki :
クラススイッチを基盤に免疫環境と免疫応答をモニターする高性能タンパクチップの臨床応用,
Clinical Immunology & Allergology, Vol.64, No.5, 488-494, Nov. 2015.
6. Hiroshi Kido :
感染症の重症化と栄養ーエネルギー代謝破綻が引き起こすインフルエンザ感染重症化,
The Japanese Journal of Clinical Nutrition, Vol.127, No.5, 622-623, Oct. 2015.
7. Hiroshi Kido :
インフルエンザ脳症の予防策,
Japan Medical Journal, No.4751, 60-61, May 2015.
8. Hiroshi Kido :
インフルエンザ感染症の予防と治療に関する新展開,
インフルエンザ, Vol.16, No.2, 89-90, 2015.
9. Hiroshi Kido :
インフルエンザ脳症とCPT-II熱不安定性遺伝子多型,
Clinician, Vol.61, No.634, 13-16, Dec. 2014.
10. Hiroshi Kido :
インフルエンザ感染の重症化機序とインフルエンザ脳症の最新知見,
室医会報, Vol.16, 113-118, Dec. 2014.
11. Hiroshi Kido, 品原 和加子 and Etsuhisa Takahashi :
インフルエンザ感染におけるマクロライドの粘膜免疫増強効果,
Respiratory Medical Research, Vol.2, No.4, 229-233, Oct. 2014.
(CiNii: 40020348454)
12. Hiroshi Kido :
インフルエンザ感染症における粘膜免疫の重要性,
Annual Review 呼吸器, 24-29, 2014.
13. Hiroshi Kido :
インフルエンザ感染の重症化機序,肺炎・脳症の最新知見と治療法の提案,
都耳鼻会報, Vol.143, 41-46, 2014.
14. Hiroshi Kido :
肺サーファクタントの新たな医学応用の可能性∼粘膜アジュバントへの応用とワクチン開発,
Respiratory Molecular Medicine, Vol.18, No.1, 171-175, 2014.
15. Hiroshi Kido :
ウイルス感染症の重症化メカニズム,
Jpurnal of Otolaryngology, Head and Neck Surgery, Vol.30, No.11, 1540-1544, 2014.
16. Hiroshi Kido :
アジュバント,
小児内科, Vol.45, 60-64, Nov. 2013.
17. Hiroshi Kido, Etsuhisa Takahashi and 山根 一彦 :
重症インフルエンザ感染の肺炎・脳症の最新知見と治療提案,
日本臨床内科医会会誌, Vol.27, No.5, 578-583, Oct. 2013.
18. Hiroshi Kido :
インフルエンザ脳症の発症機序とCPT2,
Pharma Tribune, Vol.5, No.10, 66-67, Oct. 2013.
19. Hiroshi Kido :
インフルエンザ脳症はここまでわかってきた,
プライマリケアのためのインフルエンザ診療 2013-2014, 30-35, Sep. 2013.
20. Hiroshi Kido, 多田 仁美, Norio Kamemura, 窪田 賢司 and Kouichi Suzuki :
アレルゲン特異IgE抗体の新しい測定方法 3. Diamond-Like Carbon を用いた新規高感度アレルゲンマイクロアレイの多項目抗原特異的IgE測定,
アレルギー・免疫, Vol.20, No.1, 56-62, Jan. 2013.
21. 木本 貴司, Dai Mizuno, 堺 聡子 and Hiroshi Kido :
肺サーファクタント由来人工合成粘膜アジュバントSF-10の感染防御効果と液性・細胞性免疫誘導効果「の検討,
日本肺サーファクタント・界面医学界雑誌, Vol.44, 59-61, 2013.
22. Hiroshi Kido, Etsuhisa Takahashi and 堺 聡子 :
ウイルス性気道感染症における粘膜免疫の重要性,
感染と抗菌薬, Vol.16, No.4, 361-367, 2013.
23. Hiroshi Kido, Etsuhisa Takahashi and 山根 一彦 :
インフルエンザの生体防御,
感染症内科, Vol.1, No.6, 544-551, 2013.
24. Hiroshi Kido, Etsuhisa Takahashi, Irene L. Indarao and 山根 一彦 :
インフルエンザ脳症の重症化メカニズムと対策,
Respiratory Medicine, Vol.22, No.6, 553-560, Dec. 2012.
25. Hiroshi Kido, Etsuhisa Takahashi, Kosuke Kataoka, Dai Mizuno, 木本 貴司, Chisa Fujimoto and Indarao L. Irene :
インフルエンザ感染症における粘膜免疫とその制御による治療効果の増強,
新薬と臨床, Vol.61, No.12, 2459-2470, Dec. 2012.
26. Hiroshi Kido, Etsuhisa Takahashi, Kosuke Kataoka, Dai Mizuno, 木本 貴士, Chisa Fujimoto and Indalao L Irene :
インフルエンザ感染症における粘膜免疫とその制御による治療効果の増強,
新薬と臨床, Vol.61, No.12, 2459-2470, Dec. 2012.
27. Hiroshi Kido, Etsuhisa Takahashi, I.L Indalao and Kazuhiko Yamane :
Mechanisms and treatments of severe influenza encephalopathy,
Respiratory Medicine, Vol.22, No.6, 553-560, Dec. 2012.
(CiNii: 40019551921)
28. Hiroshi Kido, Etsuhisa Takahashi, Indalao L Irene, Kazuhiko Yamane and Mineyoshi Hiyoshi :
インフルエンザの重症化,
臨床と微生物, Vol.39, No.6, 720-724, Nov. 2012.
29. Hiroshi Kido, Etsuhisa Takahashi, Kazuhiko Yamane and Mineyoshi Hiyoshi :
インフルエンザ感染の重症化機序と治療の最新知見,
大阪府内科医会会誌, Vol.21, No.2, 146-151, Nov. 2012.
30. Hiroshi Kido :
肺サーファクタントの新たな医学応用の可能性ー粘膜アジュバントへの応用とワクチン開発ー,
日本肺サーファクタント・界面医学会雑誌, Vol.43, 1-8, Oct. 2012.
31. Hiroshi Kido, Norio Kamemura, 多田 仁美 and Mineyoshi Hiyoshi :
唾液を用いたアレルギー診断の新技術と今後の展望,
BIO INDUSTRY, Vol.29, No.10, 42-47, Oct. 2012.
32. Hiroshi Kido :
体内酵素が制御するインフルエンザウイルス感染と感染の重症化,
Infection, Inflammation & Immunity, Vol.42, No.2, 36-44, Jul. 2012.
33. Kouichi Suzuki, Norio Kamemura, 多田 仁美, 窪田 賢司, 澤淵 貴子 and Hiroshi Kido :
低侵襲性高感度マルチ抗原アレルギー診断チップの開発,
アレルギーの臨床, Vol.32, No.54, 331-335, Jul. 2012.
34. Hiroshi Kido, Etsuhisa Takahashi, Dai Mizuno, 木本 貴士, Indalao L Irene and 鈴木 悟 :
マクロライド薬によるインフルエンザ感染時の粘膜免疫増強作用,
臨床と微生物, Vol.39, No.4, 331-335, Jul. 2012.
35. Hiroshi Kido and Junji Chida :
インフルエンザ脳症への新たな対応策は?,
インフルエンザの最新知見 Q & A 2012, 171-172, May 2012.
36. 水野 葉子, 久保田 雅也, 柏井 洋文, 宮田 理英, 田沼 直之, 林 雅晴, Junji Chida, 山口 美代子, Yao Dengbing, Yao Min and Hiroshi Kido :
Carnitine palmitoyltransferase II (CPT II) の熱不安定性遺伝子多型を持った急性脳症の1例,
Japanese Journal of Pediatrics, Vol.65, No.5, 1057-1062, 2012.
37. Hiroshi Kido, Etsuhisa Takahashi, Kazuhiko Yamane and Mineyoshi Hiyoshi :
インフルエンザ感染の重症化機序と予防と治療の最新知見,
大阪府内科医会誌, Vol.21, No.2, 146-151, 2012.
38. Hiroshi Kido, Etsuhisa Takahashi, Kosuke Kataoka, Mihiro Yano and 鈴木 悟 :
気道の生体防御能,粘膜免疫を増強するマクロライド系薬とインフルエンザ感染,
Medicine and Drug Journal, Vol.47, No.11, 2768-2733, Nov. 2011.
39. Hiroshi Kido :
気道の生体防御,粘膜免疫を増強するマクロライド系薬とインフルエンザ感染,
医薬ジャーナル, Vol.47, No.11, 2768-2773, Nov. 2011.
40. Hiroshi Kido :
インフルエンザの予防と対策,
Medicament News, Vol.2070, 5-7, Oct. 2011.
41. Hiroshi Kido, Yuushi Okumura, Etsuhisa Takahashi and Mihiro Yano :
Interrelationship between influenza virus and host cellular factors which exacerbates viral infection,
Respiration & Circulation, Vol.59, No.10, 973-981, Oct. 2011.
(CiNii: 40019001693,   Elsevier: Scopus)
42. Hiroshi Kido and Junji Chida :
インフルエンザ脳症の発症機序ー遺伝子多型が解き明かす発症基盤ー,
Influenza, Vol.44, No.12(3), 225-232, Oct. 2011.
(CiNii: 40019016953)
43. Hiroshi Kido :
インフルエンザウイルス感染症の重症化メカニズムと治療戦略,
呼吸器病, Vol.15, No.1, 37-39, Jul. 2011.
44. Hiroshi Kido :
インフルエンザの重症化とその対策,
インフルエンザ, Vol.12, No.2, 9-21, Feb. 2011.
45. Hiroshi Kido, Junji Chida, Yao Min, Dengbing Yao and 山根 一彦 :
遺伝子多型解析が解き明かすインフルエンザ脳症と多臓器不全,
Experimental Medicine, Vol.28, No.18, 2927-2933, Nov. 2010.
46. Hiroshi Kido and Junji Chida :
インフルエンザ感染の重症化機序,
Neuroinfection, Vol.15, No.1, 66-73, Sep. 2010.
47. Hiroshi Kido, Dai Mizuno and 木本 貴士 :
粘膜免疫機能とインフルエンザ感染,
小児内科, Vol.42, 1541-1545, Sep. 2010.
48. Hiroshi Kido, Junji Chida, Min Yao and Siye Wang :
Mechanisms of multi-organ failure in severe influemza,
Nihon Rinsho. Japanese Journal of Clinical Medicine, Vol.68, No.8, 1565-1573, Aug. 2010.
(PubMed: 20715496,   CiNii: 40017192473)
49. Hiroshi Kido, Junji Chida, Yao Min and Wang Siye :
最近のインフルエンザ治療の動向とクラリスロマイシン投与の意義,
大阪府内科医会誌, Vol.19, No.1, 47-54, Apr. 2010.
50. Hiroshi Kido :
小児インフルエンザ治療においてノイラミニダーゼ阻害薬と¥マクロライド系抗菌薬が気道粘膜免疫に及ぼす影響,
Medical Tribune, Vol.43, No.50, 4--4, 2010.
51. Hiroshi Kido, 水野 大 and 武井 恒知 :

インフルエンザ, Vol.11, No.2, 184-190, 2010.
52. Kamada Masaharu, Masahiko Maegawa, Maeda Nobuhiko, Satoshi Yamamoto, Yoshikawa Shouji, Mori Hidetoshi, Yuu Tanaka, Okada Masumi, Shitukawa Keiji, Minoru Irahara, Toshihiro Aono, Hiroshi Kido, Ogushi Fumitaka, Sono Saburo, Kanayama Naoomi, Susumu Kagawa, Ohmoto Yasukazu, Futaki Shiro, Liang Guo Zhi and Koide S. Samuel :
5. Immunoglobulin binding factor in human seminal plasma and uterine cerivical mucus,
Current Paradigm of Reproductive Immunology, 95-104, Apr. 2009.
53. Hiroshi Kido :

インフルエンザ, Vol.10, No.2, 101-103, 2009.
54. Junji Chida, Dengbing Yao, Siye Wang, Miyoko Yamaguchi and Hiroshi Kido :
インフルエンザの重症化をめぐって,
The Japanese Journal of Antibiotics, (in-press), 2009.
55. Hiroshi Kido, Dai Mizuno and Tunetomo Takei :
経鼻ワクチン,
Nihon Rinsho. Japanese Journal of Clinical Medicine, Vol.66, 1181-1187, Dec. 2008.
56. Hiroshi Kido, Dai Mizuno and Tunetomo Takei :
経鼻投与型インフルエンザワクチン,
総合臨床, Vol.57, No.11, 2628-2633, Oct. 2008.
57. Hiroshi Kido, Dai Mizuno and Tunetomo Takei :
経鼻ワクチン,
日本臨床, Vol.66, No.10, 1881-1887, Oct. 2008.
58. Hiroshi Kido :
マクロライド系抗菌薬の多彩な作用 —粘膜免疫増強作用と生体防御—,
Current Therapy, Vol.26, No.8, 717-721, 2008.
59. Hiroshi Kido, Dai Mizuno, 藤本 知佐, Tunetomo Takei, 品原 和加子, 木本 貴士 and 福田 明穂 :
インフルエンザ粘膜ワクチン研究とミニブタモデル実験動物,
分子呼吸器病, Vol.12, No.2, 43-46, 2008.
60. Hiroshi Yamada, Higashi Youichiro, Kousaka Aoi, Enomoto Tadashi and Hiroshi Kido :
Diclofenac augments intracellular influenza virus replication,
Options for the Control of Influenza VI, Vol.1, No.1, 633-635, 2008.
61. Hiroshi Kido, Dai Mizuno, Tunetomo Takei, Maki Nisino, Junji Chida and Cisse Youssof :
インフルエンザ経鼻ワクチン -肺サーファクタント粘膜免疫-,
小児科, Vol.48, No.12, 1837-1844, Nov. 2007.
62. Hiroshi Kido, Dai Mizuno, Tunetomo Takei, Maki Nisino, Junji Chida and Cisse Youssouf :
インフルエンザ経鼻ワクチン,
Pediatrics of Japan, Vol.48, No.12, 1837-1844, Nov. 2007.
63. Hiroshi Kido, Dengbing Yao, Le Trong Quang, Mariko Tsukane and Junji Chida :
Analysis of SNPs and enzymatic disorder in the patients of influenza-associated encephalopathy., --- Disorder of fatty acid metabolism in mitochondria induced by high fever. ---,
Nihon Rinsho. Japanese Journal of Clinical Medicine, Vol.64, No.10, 101-109, Oct. 2007.
64. Hiroshi Kido, Dai Mizuno, Tunetomo Takei, Maki Nisino and 品原 和加子 :
経鼻ワクチンの可能性,
インフルエンザ, Vol.8, 247-249, Jul. 2007.
65. Hiroshi Kido, Dengbing Yao, Le Trong Quang, Junji Chida, Yuushi Okumura and Hiroshi Yamada :
インフルエンザ感染,
Antibiotics and Chemotherapy, Vol.23, No.7, 101-109, Jul. 2007.
66. Hiroshi Kido, 鈴木 悟, 岩瀬 一弘, Dai Mizuno, 澤淵 貴子 and 多田 仁美 :
クラリスロマイシンの短期投与はインフルエンザ感染にどのように効果的か?—粘膜免疫増強作用と気道粘膜繊毛運動改善効果—,
Jpn.J.Antibiotics, Vol.60, No.1, 84-88, Feb. 2007.
67. 鈴木 悟, 岩瀬 一弘 and Hiroshi Kido :
急性呼吸器感染症に対するマクロライド系抗菌薬の可能性,
ライフ・サイエンス, Vol.27, No.10, 163-166, 2007.
68. Hiroshi Kido :
エンドセリン受容体,
Medical Tribune, Vol.40, No.26, 57, 2007.
69. Hiroshi Kido, Dengbing Yao, Le Quang Trong, Junji Chida, Yuushi Okumura and Hiroshi Yamada :
インフルエンザ感染,インフルエンザ脳症の制圧に向けて,科学治療の領域,
Antibiotics & Chemotherapy, Vol.23, No.7, 101-109, 2007.
70. Hiroshi Kido, Dai Mizuno, Maki Nisino, 臼木 孝行 and Tunetomo Takei :
肺サーファクタントの粘膜アジュバント作用,
臨床免疫・アレルギー科, Vol.46, No.411, 415, Dec. 2006.
71. Mineyoshi Hiyoshi, Hirokazu Uemura, Hideo Takeda, Hiroshi Kido and Kokichi Arisawa :
Introduction of proteomic approach to environmental medicine,
Japanese Journal of Hygiene, Vol.61, No.4, 393-399, Sep. 2006.
72. Hiroshi Kido, Dai Mizuno and 井手 美喜子 :
クラリスロマイシンの粘膜免疫増強作用とインフルエンザウイルスの感染抑制効果,
感染・炎症・免疫, Vol.35, 61-63, Dec. 2005.
73. Hiroshi Kido, Yuushi Okumura, Le Trong Quang, 端山 昌樹, Etsuhisa Takahashi, 小沢 綾子 and 富田 勉 :
インフルエンザウイルスおよびSARSコロナウイルス:生体内プロテアーゼとウイルスの感染分子機構,
Antibiotics and Chemotherapy, Vol.21, No.5, 673-679, May 2005.
74. Hiroshi Kido, Ye Chen, Hiroshi Yamada, 東 洋一郎 and Dai Mizuno :
インフルエンザ脳症の発症機序,
神経内科, Vol.60, 119-127, Feb. 2004.
75. Hiroshi Kido, Yuushi Okumura, Hiroshi Yamada, 井手 美喜子 and Dai Mizuno :
抗インフルエンザ作用を示す去痰剤の不思議,新たな薬理作用と機序,
アレルギー科, Vol.116, 232-239, Feb. 2004.

Proceeding of International Conference:

1. kawamoto Norio, Norio Kamemura, Hiroshi Kido and Fukao Toshiyuki :
Detection of Ovomucoid-Specific Low-Affinity IgE in 14-Month-Old Infants and Its Relationship with Eczema,
American Academy of Allergy Asthma and Immunology, ロサンゼルス (アメリカ合衆国), Mar. 2016.
2. Ohya Yukihiro, Horimukai Kenta, Morita Kumiko, Narita Masami, Niizeki Hironori, Inoue Eisuke, Norio Kamemura, Hiroshi Kido and Saito Hirohisa :
A randomized, controlled intervention trial of early emollient use in prevention of atopic dermatitis and allergic sensitization during infancy,
Collegium Internatuonale Allergologicum, Petersberg, Germany, 91, Sep. 2014.
3. Mayumi Sugimoto, Norio Kamemura, Suzuki Koichi, Kubota Kenji, Nagao Mizuho, Fujisawa Takao, Shoji Kagami and Hiroshi Kido :
Analysis of Allergen-Specific Immunoglobulin in Rush Oral Immunotherapy for Severe Food Allergy by a Highly Sensitive Allergen Microarray,
European Academy of Allergy and Clinical Immunology Congress 2014, Jun. 2014.
4. Hiroshi Kido :
Critical illness and energy metabolism-Blood lactate/ATP ratio as a real-time energy alarm index-,
The 7th Asian Conference on Emergency Medicine, Oct. 2013.
5. Naoki Shimojo, Norio Kamemura, Morita Yoshinori, Tada Hitomi, Kubota Kenji, Mineyoshi Hiyoshi, Suzuki Koichi, Ichioka Takao, Kohno Yoichi and Hiroshi Kido :
Allergen sensitization develops in utero: analysis of allergen-specific antibodies by a highly-sensitive new allergen microarray,
European Academy of Allergy and Clinical Immunology Congress 2012, Jun. 2012.
6. Yuushi Okumura, Etsuhisa Takahashi and Hiroshi Kido :
TYPE II TRANSMEMBRANE SERINE PROTEASES MSPL AND TMPRSS13 PROTEOLYTICALLY ACTIVATE MEMBRANE FUSION ACTIVITY OF HIGHLY PATHOGENIC AVIAN INFLUENZA VIRUS AND INDUCE THEIR MULTICYCLE REPLICATION,
7th General Meeting of the International Proteolisis Society, San Diego, Oct. 2011.
7. Etsuhisa Takahashi, HY Pan, IL Indalao, Junji Chida and Hiroshi Kido :
TRYPSIN KOCKDOWN AND TRYPSIN INHIBITOR ADMINISTRATION SUPPRESSED INFLUENZA VIRAL REPLICATION AND VIRUS-INDUCES MYOCARDITIS IN THE HEARTS AND CARDIOMYOBLAST CELLS,
7th General Meeting of the International Proteolisis, San Diego, Oct. 2011.
8. Dai Mizuno, Kimoto Takashi, Tunetomo Takei, Kunimi Takuya and Hiroshi Kido :
Synthetic antigen vehicle SF-10 adjuvant, mimicking human pulmonary surfactant, for effective intranasal flu vaccine,
International Union of Microbiological Societies 2011, Sep. 2011.
9. Dai Mizuno, Kimoto Takashi, Tunetomo Takei, Kunimi Takuya and Hiroshi Kido :
Sy thetic antigen vehicle SF-10 adjuvant, mimicking human pulmonaru surfactant, for effective flu vaccine,,
International Union of Microbiological Societies 2011, Sep. 2011.
10. Etsuhisa Takahashi, Yuushi Okumura and Hiroshi Kido :
Type II membrane-bound proteases, MSPL and TMPRSS13, cleave hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication,
IUMS 2011, 札幌コンベンションセンター, Sep. 2011.
11. Hiroshi Kido, Junji Chida, Siye Wang, Hai-Yan Pan and Min Yao :
Influenza-Cytokine-Protease Cycle in the pathogenesis of vascular hyperpermeability in severe influenza and its possible treatments,
BMB2010, Dec. 2010.
12. Yuushi Okumura, Etsuhisa Takahashi, Oto Takahiro, Ohuchi Masanobu, Daidoji Tomo, Nakaya Takaaki, Bottcher Eva, Garten Wolfgan, Klenk Hans-Dieter and Hiroshi Kido :
Novel type transmembrane serine proteases, MSPL and TMPRSS13,proteolytically activate membrane fusion activity of hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication,
Cell symposia influenza, Washington D.C., USA, Dec. 2010.
13. Hiroshi Kido, Etsuhisa Takahashi, Kosuke Kataoka, K. Fujii, S. Suzuki and C. Ito :
Attenuation of Respiratory Immune Responses by Antiviral Neuraminidase Inhibitor Treatment and Boost of Mucosal Immunoglobulin A Response by Coadministration of Immunomodulator Clarithromycin in Pediatric Imfluenza,
Options fot the Control of Influenza, Hong Kong SAR, China, Sep. 2010.
14. Etsuhisa Takahashi, Yuushi Okumura and Hiroshi Kido :
Novel type II transmembrane serine proteases, MSPL and TMPRSS13, proteolytically activate membrane fusion activity of hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication,
Options for the Control of Influenza VII, China, Hong Kong, Sep. 2010.
15. Takashi Kimono, Dai Mizuno, Tunetomo Takei, Takuya Kunimi, Shinji Ono, Wakako Shinahara and Hiroshi Kido :
Synthetic antigen vehicle SF-10 adjuvant, mimicking human pulmonary surfactant, for effective intranasal flu vaccine.,
Options for the Control of Influenza VII, China, Hong Kong, Sep. 2010.
16. Junji Chida, Siye Wang, Haiyan Pan, Min Yao, Dengbing Yao, Kazuhiko Yamane and Hiroshi Kido :
Influenza virus-cytokine-protease cycle and mitochondrial ATP depletion are the principal mechanisms of multi-organ failure in severe influenza and therapeutic approaches,
Options for the Control of Influenza VII, China, Hong Kong, Sep. 2010.
17. Junji Chida, Siye Wang, Hai-Yan Pan, Min Yao, Dengbing Yao, Kazuhiko Yamane and Hiroshi Kido :
Influenza virus-cytokine-protease cycle and mitochondrial ATP depletion are the principal mechanisms of multi-organ failure in severe influenza and therapeutic approaches.,
Oprions for the Control of Influenza, Hong Kong, Sep. 2010.
18. Fujimoto Chisa, Hiroshi Kido, Yamaguchi Miyoko, Matsunaga Atsushi, Sawada Ayako, Tanaka Takeshi and Noriaki Takeda :
Changes in Levels of Nasal IgA and Serum IgG Antibodies against Influenza Virus Antigen in Patients with Natural Influenza Infection,
The 7th International Symposium on Tonsils and Mucosal Barriers of the Upper Airways, Asahikawa, Jul. 2010.
19. Youssouf Cisse, Siye Wang, Isao Inoue and Hiroshi Kido :
Hyperthermia induced abnormal neuronal responses in the hippocampus of rat brain after influenza A virus infection.,
Neuroelectronics Research Flanders, (Mini-Symposium), Leuven, Belgium, Oct. 2009.
20. Yuushi Okumura and Hiroshi Kido :
Role of the host cellular processing proteases in influenza virus infection.,
6th General Meeting of the International Proteolysis Society, Queensland, Australia, Oct. 2009.
21. Etsuhisa Takahashi, Yuushi Okumura and Hiroshi Kido :
Type Transmembrane Serine Proteases, MSPL and TMPRSS13, Proteolytically Activate Membrane Fusion Activity of Highly Pathogenic Avian Influenza Virus Hemagglutinin.,
6th General Meeting of the International Proteolysis Society, Queensland, Australia, Oct. 2009.
22. Siye Wang, Le Quang Trong, Hiroshi Yamada and Hiroshi Kido :
Influenza Virus-TNF-α-Protease Cycle for Progression of Influenza Virus Infection.,
6th General Meeting of the International Proteolysis Society, Queensland, Australia, Oct. 2009.
23. Etsuhisa Takahashi, Yuushi Okumura and Hiroshi Kido :
Type II Transmembrane Serine Proteases, MSPL and TMPRSS13, Proteolytically Activate Membrane Fusion Activity of Highly Pathogenic Avian Influenza Virus Hemagglutinin.,
6th General Meeting of the International Proteolysis Society, Queensland, Australia, Oct. 2009.
24. Hiroshi Kido, Dai Mizuno, Tunetomo Takei, Shinahara Wakako, Fukuda Akiho and Kimoto Takashi :
Immune responses to nasal vaccination of HA vaccine witha new natural mucosal adjuvant, pulmonary surfactantmedicine Surfacten and its synthetic compound in miceand mini-pigs,
Second Circular and Provisional Conference Programme for IVW 2009The Third International Conference onInfluenza Vaccines for the World, France, Apr. 2009.
25. Hiroshi Kido, Yuushi Okumura, Etsuhisa Takahashi and 潘 海燕 :
Novel Proteolytic Activation Protease of Highly Pathogenic Avian Influenza Viruses which cover wide strains, even for non-susceptible strains by Furin and PC5/6.,
BirdFlu2008, Oxford, Sep. 2008.
26. Junji Chida, Siye Wang, Tadashi Enomoto, Yuushi Ohnishi and Hiroshi Kido :
Up-regulations of ectopic pancreatic trypsin mRNAs by influenza virus infection and pathological role of them in multi-organ failure after virus infection.,
5th International Proteolysis Society, Patras, Oct. 2007.
27. Junpei Imajo, Masatake Akutagawa, Yohsuke Kinouchi, Fumio Shichijo and Hiroshi Kido :
Effect of Carnitine Ingestion on EEG,
Proceedings of 2006 World Congress on Medical Physics and Biomedical Engineering, Seoul, Korea, August 27-September 1, 2006, Vol.1, 1137-1140, Seoul, Aug. 2006.
28. Mineyoshi Hiyoshi, Hirokazu Uemura, Hideo Takeda, Hiroshi Kido and Kokichi Arisawa :
Quantitative proteomic analysis of testes in treated and untreated mice with bisphenol A by MALDI-TOF/TOF,
20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress, Kyoto, Jun. 2006.
29. Dai Mizuno, Mikiko Ide-Kurihara, Tomoko Ichinomiya, Itsuka Kubo, Tunetomo Takei, Maki Nisino, Takayuki Usuki and Hiroshi Kido :
Modified pulmonary surfactant is a novel antigen vehicle for influenza virus antigen to nasal-associated lymphoid tissues.,
20th International Congress of Biochemistry and Molecular Biology, Kyoto, Jun. 2006.
30. Satoshi Yamamoto, Anna Tani, Ayako Nakajima, Dan Kinoshita, Yuka Kasai, Masahiko Maegawa, Masaharu Kamada, Yuji Okumura, Hiroshi Kido and Minoru Irahara :
Development of an Expression Vector Encoding Sperm Protein,Designated RSMP-B,as an Immunocontrraceptive Vaccine,
IX International Congress of Reproductive Immunology, Vol.52, No.Supplement 1, 55, Kanagawa, Oct. 2004.
31. Masahiko Maegawa, Satoshi Yamamoto, Ayako Nakajima, Dan Kinoshita, Masayo Kanayama, Minoru Irahara, Masaharu Kamada, Yuji Okumura and Hiroshi Kido :
Development of an Expression Vector Encoding Sperm Protein,Designated rSMP-B,as an Immunocontrraceptive,
The 4th Conference of the Pacific Rim Society for Fertility and Sterility, Okinawa, Mar. 2004.

Proceeding of Domestic Conference:

1. Hiroshi Kido, Makoto Irahara, 品原 和加子, Mayumi Sugimoto and Shoji Kagami :
生後6ヵ月までの母乳栄養児と人工乳栄養児の抗原摂取量の違いを背景とした湿疹誘発IgEクラススイッチパターンの違い,
第54回日本小児アレルギー学会学術大会, Nov. 2017.
2. Makoto Irahara, 佐々木 陽平, 品原 和加子, Mayumi Sugimoto, Shoji Kagami and Hiroshi Kido :
乳児期におけるイムノグロブリンクラススイッチの進展と抗原親和性,
第66回日本アレルギー学会学術大会, Jun. 2017.
3. Makoto Irahara, 佐々木 陽平, 品原 和加子, Mayumi Sugimoto, Shoji Kagami and Hiroshi Kido :
0-6ヵ月乳児のアレルゲン特異的抗体価イムノグロブリンクラススイッチの検討,
第65回日本アレルギー学会学術大会, Jun. 2016.
4. Makoto Irahara, 佐々木 陽平, 品原 和加子, Mayumi Sugimoto, Shoji Kagami and Hiroshi Kido :
乳児期の卵白アレルゲン特異的IgE抗体の低から高親和性変化の検討,
第65回日本アレルギー学会学術大会, Jun. 2016.
5. Hiroshi Kido :
アレルギーの発症と治癒の免疫応答をクラススイッチからモニタリングする高性能タンパクチップ有用性とその臨床応用,
第34回日本耳鼻咽喉科免疫アレルギー学会, 41, Feb. 2016.
6. Hiroshi Kido :
インフルエンザ感染の予防と,重症化治療の最新知見,
第8回「ナノカーボンバイオセンサーの医療応用研究会」, Jan. 2016.
7. Hiroshi Kido :
インフルエンザ感染の重症化機序と,その予防と治療の最新知見,
Journal of the Japanese Society of Intensive Care Medicine, Vol.23, 46, Jan. 2016.
8. Etsuhisa Takahashi, Indalao Lorinda Irene, 澤淵 貴子, 冨永 ゆかり and Hiroshi Kido :
インフルエンザ重症化で発現増加するMMP-9はクラリスロマイシンの投与により抑制される,
Aug. 2015.
9. Etsuhisa Takahashi and Hiroshi Kido :
インフルエンザ重症化におけるクラリスロマイシンの治療効果の検討,
Jul. 2015.
10. Hiroshi Kido, Etsuhisa Takahashi and Indalao L. Irene :
サイトカインストームによる代謝破綻と感染重症化にたいする治療薬の開発,
第15回日本蛋白質科学会年会, 51, Jun. 2015.
11. Mayumi Sugimoto, Norio Kamemura, 長尾 みづほ, Shoji Kagami, 藤澤 隆夫 and Hiroshi Kido :
急速経口免疫療法における抗原特異的IgGおよびIgAと予後に関する検討,
第64回日本アレルギー学会学術大会, May 2015.
12. Hiroshi Kido :
クラススイッチを基盤に免疫応答をモニターする高性能タンパクチップの臨床応用,
第64回日本アレルギー学会学術大会, Vol.64, No.3,4, 258, May 2015.
13. Norio Kamemura, noiro kawamoto, 中村 亮介, 手島 玲子, 下条 直樹, 深尾 敏幸 and Hiroshi Kido :
新規蛋白チップによる臍帯血特異的IgEの検出と,離乳完了期までに見られるIgE抗体の低親和性から高親和性への変化,
第51回 日本小児アレルギー学会, 四日市, Nov. 2014.
14. Hiroshi Kido :
勝沼信彦先生と共に歩んだプロテアーゼの病態代謝研究:インフルエンザ感染の重症化とその予防と治療,
第19回日本病態プロテアーゼ学会, Aug. 2014.
15. Hiroshi Kido :
インフルエンザ治療におけるマクロライドのイムノモジュレーター効果と作用機序,
第21回マクロライド新作用研究会, Jul. 2014.
16. Hiroshi Kido :
経鼻接種インフルエンザ粘膜ワクチン開発の現状,
第88回日本感染症学会学術講演会, Jun. 2014.
17. Mayumi Sugimoto, Norio Kamemura, 鈴木 宏一, 窪田 賢司, 長尾 みづほ, 藤澤 隆夫, Shoji Kagami and Hiroshi Kido :
高感度定量測定法による,急速経口免疫療法における抗原特異的免疫グロブリンの検討,
第26回日本アレルギー学会春季臨床大会, May 2014.
18. Hiroshi Kido :
肺サーファクタントの新たな医学応用の可能性ー粘膜アジュバントへの応用とワクチン開発ー,
第21回肺サーファクタント分子病態研究会, Jun. 2013.
19. Etsuhisa Takahashi, Kosuke Kataoka, Indalao Lorinda Irene and Hiroshi Kido :
インフルエンザ感染時のタミフル服用により低下した気道粘膜IgAはクラリスロマイシンと併用することによって改善される,
第54回日本生化学会中国四国支部例会, May 2013.
20. Chisa Fujimoto, Hiroshi Kido and Noriaki Takeda :
Induction and maintenance of anti-influenza antigenspecific nasal secretory IgA levels and serum IgG revuls after influenza infection in adults,
第41回日本免疫学会学術集会, Dec. 2012.
21. 木葉 敬子, Etsuhisa Takahashi, Kosuke Kataoka, Indalao Lorinda Irene and Hiroshi Kido :
Airway mucosal IgA which reduced by oseltamivir is improved by combination with Clarithromycin in mice infected with influenza A virus,
第85回日本生化学会大会, Dec. 2012.
22. Etsuhisa Takahashi, Yuushi Okumura, Indalao L Irene, 木葉 敬子 and Hiroshi Kido :
Novel type II transmembrane serine proteases, MSPL/TMPRSS13 knockout mice attenuates multicycle replication of highly pathogenic avian influenza viruses,
第85回日本生化学会大会, Dec. 2012.
23. Hiroshi Kido :
インフルエンザ感染の重症化とその対策,
三府県内科医会合同学術講演会, Nov. 2012.
24. Hiroshi Kido :
重症のインフルエンザによる肺炎・脳症の最新知見と,診断・治療への提案,
第26回日本臨床内科医学会, Oct. 2012.
25. Etsuhisa Takahashi, Yuushi Okumura, Indalao L Irene, 木葉 敬子 and Hiroshi Kido :
II型膜結合型プロテアーゼMSPL/TMPRSS13-KOマウスにおける高病原性鳥インフルエンザウイルス(H5N1)の感染病態解析,
第17回日本病態プロテアーゼ学会学術集会, Aug. 2012.
26. Hiroshi Kido :
インフルエンザ感染の重症化機序と予防と治療の最新知見,
第36回長崎感染症研究会, Mar. 2012.
27. Mutsuo Onodera, Emiko Nakataki, Junji Chida, Hideaki Imanaka, Hiroshi Kido and Masaji Nishimura :
ICU入室患者における末梢血アデノシン三リン酸(ATP)と転帰との関係,
第39回日本集中治療医学会総会, Feb. 2012.
28. 木本 貴士, Dai Mizuno and Hiroshi Kido :
ヒト肺サーファクタント由来SF-10アジュバントを用いた経鼻インフルエンザワクチンによる抗体産生細胞の鼻腔内局在と抗体サブタイプの検討,
第15回 日本ワクチン学会学術集会, Dec. 2011.
29. Hiroshi Kido :
肺サーファクタントの新たな医療応用への可能性ー粘膜アジュバントへの応用とワクチン開発ー,
第47回日本肺サーファクタント・界面医学会 ,会長講演,徳島, Oct. 2011.
30. 木本 貴士, Dai Mizuno, Tunetomo Takei and Hiroshi Kido :
肺サーファクタント由来人工合成粘膜アジュバントSSFの抗原取込増強機構の解析,
第47回 肺サーファクタント界面医学会・学術集会,徳島, Oct. 2011.
31. Dai Mizuno, 木本 貴士, Tunetomo Takei, 品原 和加子 and Hiroshi Kido :
肺サーファクタント由来人工合成粘膜アジュバントSF10の開発と抗体誘導効果の検討,
日本肺サーファクタント・界面医学会・第47回学術研究会,徳島, Oct. 2011.
32. 木本 貴士, Dai Mizuno and Hiroshi Kido :
ヒト肺サーファクタント類似合成粘膜アジュバントSF-10による効果的な生体免疫応答と,抗インフルエンザ特異抗体の誘導機序 京都,
第84回 日本生化学会大会,東京, Sep. 2011.
33. CISSE S.A Tidiane, Masatake Akutagawa, Takahiro Emoto, Youssouf Cisse, Yohsuke Kinouchi and Hiroshi Kido :
The effect of Carnitine on human brain,
Journal of Shikoku-Section Joint Convention of the Institutes of Electrical and Related Engineers, 249, Sep. 2011.
34. Etsuhisa Takahashi, Yuushi Okumura, Indalao L Irene, 中屋 隆明, 大道寺 智 and Hiroshi Kido :
高病原性鳥インフルエンザウイルスヘマグルチニンの新規活性化酵素,Ⅱ型膜結合型セリンプロテアーゼのMSPL/TMPRSS13の性状解析,
第84回日本生化学会大会, Sep. 2011.
35. Etsuhisa Takahashi, Yuushi Okumura and Hiroshi Kido :
Ⅱ型膜結合型セリンプロテアーゼ,MSPL/TMPRSS13は高病原性鳥インフルエンザウイルスHAを切断し,ウイルスの増殖を活性化する,
第16回 日本病態プロテアーゼ学会 (JSPP), Aug. 2011.
36. Hiroshi Kido :
インフルエンザ感染症におけるマクロライドのイムノモジュレーター作用の高い有用性,
第18回マクロライド新作用研究会,東京, Jul. 2011.
37. Rie Ono, Masaji Nishimura, Jun Oto, Hideaki Imanaka, Junji Chida and Hiroshi Kido :
重症患者の末梢血ATP乳酸値比,
日本麻酔科学会第58回学術集会,神戸, May 2011.
38. 藤本 知佐, Noriaki Takeda, 山口 美代子, Hiroshi Kido, 澤田 亜也子, 松永 敦 and 田中 健 :
インフルエンザ感染者の鼻腔IgG抗体の感染後の経時変化,
第112回日本耳鼻咽喉科学会,京都, May 2011.
39. Norio Kamemura, 多田 仁美, Kouichi Suzuki, 窪田 賢司, 河野 陽一, 下条 直樹, 森田 慶紀, 市橋 隆男 and Hiroshi Kido :
食物,吸入抗原に対する特異的抗体の臍帯血と母体血の関係,
第23回日本アレルギー学界春季臨床大会,千葉(幕張), May 2011.
40. Norio Kamemura, 多田 仁美, 河野 陽一, 下条 直樹, 森田 慶紀, 市岡 隆男, Kouichi Suzuki, 窪田 賢司 and Hiroshi Kido :
臍帯血のアレルゲン特異抗体の検出と各種抗体の母子移行評価 ,,
第23回日本アレルギー学会春季臨床大会, 千葉(幕張), May 2011.
41. 藤本 知佐, Hiroshi Kido, 山口 美代子, 松永 敦, 澤田 亜矢子, 田中 腱 and Noriaki Takeda :
インフルエンザ感染者の鼻腔IgA抗体と血清IgG抗体の感染後の経時変化,
第29回日本耳鼻咽喉科免疫アレルギー学会, Feb. 2011.
42. 木本 貴士, Dai Mizuno, Tunetomo Takei, 国見 卓也, 小野 慎司, 品原 和加子 and Hiroshi Kido :
肺サーファクタント由来SF-10アジュバントによる経鼻インフルエンザワクチンの抗体誘導効果,
第14回日本ワクチン学会学術集会, Dec. 2010.
43. Mihiro Yano and Hiroshi Kido :
熱ストレスによる腸管上皮細胞間タイトジャンクションの崩壊機構,
第83回日本生化学会大会, 194, Dec. 2010.
44. Dai Mizuno, Tunetomo Takei, Takashi Kimono, Wakako Shinahara, Takuya Kunimi, Shinjji Ono and Hiroshi Kido :
Effects of synthetic mucosal adjuvant SF10 on local and systemic antibody production by intranasal influenza vaccination.,
第33回日本分子生物学会年会 第83回 日本生化学会大会合同大会,, Dec. 2010.
45. Min Yao, Junji Chida, Hiyan Pan, Siye Wang and Hiroshi Kido :
Effect of Bezafibrate on mitochondrial energy crisis in the fibroblast of severe influenza-associated encephalopathy patients,
第33回日本分子生物学会年会 第83回 日本生化学会大会合同大会,, Dec. 2010.
46. Junji Chida, Min Yao, Dengbing Yao, Miyoko Yamaguchi and Hiroshi Kido :
Pathogenesis of impaired systemic energy metabolism by severe influenza virus infection Analysis using mouse models of defect in mitochondrial -oxidation of long-chain fatty acids,
第33回日本分子生物学会年会 第83回 日本生化学会大会合同大会,, Dec. 2010.
47. Hiroshi Kido, Junji Chida, Siye Wang, Hiyan Pan and Min Yao :
Influenza-Cytokine-Protease Cycle in the pathogenesis of vascular hyper-permeability in severe influenza and its possible treatment,
第33回日本分子生物学会年会 第83回 日本生化学会大会合同大会,, Dec. 2010.
48. 藤本 知佐, Noriaki Takeda, Hiroshi Kido, 山口 美代子, 松永 敦, 澤田 亜也子 and 田中 健 :
インフルエンザ感染症の鼻腔IgA抗体と血清IgG抗体の感染後の経時変化,
日本耳鼻咽喉科学会第36回四国四県地方部会, Dec. 2010.
49. Etsuhisa Takahashi, Yuushi Okumura, 大内 正信, Klenk Hans-Dieter, 中屋 隆明, 大道寺 智 and Hiroshi Kido :
Novel type II transmembrane serine proteases, MSPL and TMPRSS13, proteolytically activate membrane fusion activity of hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication,
第83回日本生化学会大会, Dec. 2010.
50. Yao Min, Etsuhisa Takahashi, Pan Haiyan, Junji Chida and Hiroshi Kido :
A Type II Transmembrane Serine Protease Serase-1B, a New Splice Variant of Polyserase-1/TMPRSS9, Plays a Role in Adipogenesis.,
第83回日本生化学会大会, Dec. 2010.
51. Hai-Yan Pan, Junji Chida and Hiroshi Kido :
Up-regulation of ectopic trypsin in myocardium triggers acute myocarditis in severe influenza,
Seikagaku, Dec. 2010.
52. Min Yao, Junji Chida, Hai-Yan Pan, Siye Wang and Hiroshi Kido :
Effect of Bezafibrate on mitochondrial energy crisis in the fibroblast of severe influenza-associated encephalopathy patients,
Seikagaku, Dec. 2010.
53. Junji Chida, Min Yao, Dengbing Yao, Miyoko Yamaguchi and Hiroshi Kido :
Pathogenesis of impaired systemic energy metabolism by severe influenza virus infection Analysis using mouse models of defect in mitochondrial -oxidation of long-chain fatty acids-,
Seikagaku, Dec. 2010.
54. Hiroshi Kido, Junji Chida, Siye Wang, Hai-Yan Pan and Min Yao :
Influenza-Cytokine-Protease Cycle in the pathogenesis of vascular hyper-permeability in severe influenza and its possible treatment.,
Seikagaku, Dec. 2010.
55. Etsuhisa Takahashi, Yuushi Okumura, 大内 正信, Klenk Hans-Dieter, 中屋 隆明, 大道寺 智 and Hiroshi Kido :
高病原性鳥インフルエンザウイルスはⅡ型膜結合型セリンプロテアーゼのMSPL/TMPRSS13によってヘマグルチニンが切断され,膜融合が活性化される,
第58回日本ウイルス学会学術集会, Nov. 2010.
56. Tidiane Seck Ahmed Cisse, Masatake Akutagawa, Takahiro Emoto, Yohsuke Kinouchi and Hiroshi Kido :
The effect of Carnitine on human brain,
Journal of Shikoku-Section Joint Convention of the Institutes of Electrical and Related Engineers, 205, Sep. 2010.
57. Junji Chida, Siye Wang, Dengbing Yao, Min Yao, Miyoko Yamaguchi and Hiroshi Kido :
インフルエンザ脳症の発症メカニズムの酵素学的な解析,
温熱生理研究会, Sep. 2010.
58. Hiroshi Kido :
インフルエンザはなぜ恐い-重症化機序における宿主因子のプロテアーゼとエネルギー代謝-,
第15回日本病態プロテアーゼ学会, Aug. 2010.
59. 高橋 悦久, Yuushi Okumura and Hiroshi Kido :
Ⅱ型膜結合型セリンプロテアーゼ,MSPL/TMPRSS13による高病原性鳥インフルエンザウイルス感染活性化と,その阻害剤の検討,
第15回日本病態プロテアーゼ学会学術集会, Aug. 2010.
60. Etsuhisa Takahashi, Yuushi Okumura and Hiroshi Kido :
Ⅱ型膜結合型セリンプロテアーゼ,MSPL/TMPRSS13による高病原性鳥インフルエンザウイルス感染活性化と,その阻害剤の検討,
第15回日本病態プロテアーゼ学会学術集会, Aug. 2010.
61. Hiroshi Kido :
抗インフルエンザ薬のタミフル,リレンザの服用で気道粘膜の抗ウイルスIgA抗体の産生は抑制されるが,マクロライドの併用はこれを回復させる,
第17回マクロライド新作用研究会, Jul. 2010.
62. Hiroshi Kido :
インフルエンザ感染に伴う体内代謝の変動と感染重症化の機序,診断マーカーと治療,
第58回日本化学治療法学会総会, Jun. 2010.
63. 藤本 知佐, Hiroshi Kido, 山口 美代子, 松永 敦, 澤田 亜也子, 田中 健 and Noriaki Takeda :
インフルエンザ感染者の鼻腔IgA抗体と血清IgG抗体の感染後の経時変化,
第28回日本耳鼻咽喉科免疫アレルギー学会, Feb. 2010.
64. Etsuhisa Takahashi, Yuushi Okumura and Hiroshi Kido :
高病原性トリインフルエンザウイルスはII型膜結合型セリンプロテアーゼ,MSPL/TMPRSS13により活性化され,その膜融合活性はインヒビターによって低下する,
第82回日本生化学会大会, Oct. 2009.
65. Etsuhisa Takahashi, 潘 海燕, Yuushi Okumura and Hiroshi Kido :
高病原性鳥インフルエンザウイルス感染活性化酵素として新たに見出されたⅡ型膜結合型セリンプロテアーゼ,MSPL/TMPRSS13による膜融合活性の証明,
第14回日本病態プロテアーゼ学会学術集会, Aug. 2009.
66. 藤本 知佐, Noriaki Takeda and Hiroshi Kido :
インフルエンザワクチン皮下接種の局所免疫および全身免疫に対する効果,
第66回日本耳鼻咽喉科学会徳島県地方部会, Mar. 2009.
67. 藤本 知佐, Noriaki Takeda, Hiroshi Kido, 澤淵 貴子, 品川 和佳子, 山口 美代子 and Hiroaki Yanagawa :
インフルエンザワクチン皮下接種の局所免疫および全身免疫に対する効果-経鼻粘膜ワクチン開発に向けた評価法の検討-,
第27回日本耳鼻咽喉科免疫アレルギー学会, Feb. 2009.
68. 木本 貴士, Dai Mizuno, 福田 明穂, Tunetomo Takei, 品原 和加子 and Hiroshi Kido :
人工合成ヒト肺サーファクタントプロテインCのアジュバント活性に必要なペプチド配列の探索,
第 81 回日本生化学会大会・第 31 回日本分子生物学会年会合同大会, Dec. 2008.
69. 福田 明穂, 澤淵 貴子, 品原 和加子, Dai Mizuno and Hiroshi Kido :
現行インフルエンザワクチンの鼻腔粘膜IgA誘導能と,感染者と非感染者の鼻腔粘膜IgA量の検討,
第 81 回日本生化学会大会・第 31 回日本分子生物学会年会合同大会, Dec. 2008.
70. Etsuhisa Takahashi, Yuushi Okumura, 潘 海燕 and Hiroshi Kido :
II型膜結合型セリンプロテアーゼ,MSPL/TMPRSS13は高病原性トリインフルエンザウイルスを活性化し,膜融合活性能を増大する.,
第81回日本生化学会大会, Dec. 2008.
71. Yuushi Okumura, Etsuhisa Takahashi, 潘 海燕 and Hiroshi Kido :
マウスII型膜結合型セリンプロテアーゼ,MSPL/TMPRSS13の同定およびヒト型との機能解析比較,
第81回日本生化学会大会, Dec. 2008.
72. Junji Chida, Tadashi Enomoto, Hiroki Arase and Hiroshi Kido :
Molecular pathogenesis and multiplicity of influenza virus A/WSN/33 in plasminogen deficient mice.,
第81回 日本生化学会大会, Dec. 2008.
73. Yuuji Onishi, Junji Chida, Cisse Youssouf and Hiroshi Kido :
Molecular mechanism of the decrease in ATP levels by influenza virus infection.,
第81回 日本生化学会大会, Dec. 2008.
74. Min Yao, Dengbing Yao, Miyoko Yamaguchi, Junji Chida and Hiroshi Kido :
Effect of bezafibrate on mitochondrial energy crisis in the fibroblasts of severe influenza-associated encephalopathy patients.,
第81回 日本生化学会大会, Dec. 2008.
75. Hiroshi Kido, 福田 明穂, 木本 貴士, Tunetomo Takei, 品原 和加子 and Dai Mizuno :
インフルエンザ感染を左右する気道粘膜免疫の重要性と,生体成分粘膜ワクチンアジュバントを用いた経鼻ワクチン開発,
第12回 日本ワクチン学会 学術集会, Nov. 2008.
76. Etsuhisa Takahashi, 潘 海燕, Yuushi Okumura and Hiroshi Kido :
最長の細胞内領域とリン酸化シグナルを持つ,新規Ⅱ型膜結合型セリンプロテアーゼ,MSPL/TMPRSS13はMulti-basicシグナルを特異的に認識する唯一の膜結合型酵素であった,
第13回日本病態プロテアーゼ学会学術集会, Aug. 2008.
77. Etsuhisa Takahashi, 潘 海燕, Yuushi Okumura and Hiroshi Kido :
高病原性鳥インフルエンザウイルスの感染活性化酵素の発見;新規Ⅱ型膜結合型セリンプロテアーゼ,MSPL/TMPRSS13によるウイルス膜融合活性と感染性の発現,
第13回日本病態プロテアーゼ学会学術集会, Aug. 2008.
78. Junji Chida, Talukder R Sadiqur, Yuushi Okumura and Hiroshi Kido :
インフルエンザ感染後に発現誘導されるトリプシン遺伝子群の転写制御ネットワーク,
第13回 病態と治療におけるプロテアーゼとインヒビター学会, Aug. 2008.
79. Arase Hiroki, Junji Chida, Tadashi Enomoto and Hiroshi Kido :
インフルエンザウイルスの活性化・増殖仮説のプラスミノーゲン KO マウスを用いた検証,
第13回 病態と治療におけるプロテアーゼとインヒビター学会, Aug. 2008.
80. Junji Chida, Dengbing Yao, Siye Wang, Miyoko Yamaguchi and Hiroshi Kido :
インフルエンザ脳症発症の分子機序の解明,
第15回 マクロライド新作用研究会, Jul. 2008.
81. 藤本 知佐, Noriaki Takeda and Hiroshi Kido :
鼻腔噴霧吸引法(Nasal Splay and Aspiration)の開発と鼻腔IgA分泌の評価,
日本耳鼻咽喉科学会徳島県地方部会第65回学術講演会, Mar. 2008.
82. 藤本 知佐, Noriaki Takeda and Hiroshi Kido :
鼻腔噴霧吸引法(Nasal Splay and Aspiration)の開発と鼻腔IgA分泌の評価,
第26回日本耳鼻咽喉科免疫アレルギー学会, Feb. 2008.
83. 端山 昌樹, 田村 学, 村田 潤子, 識名 崇, 久保 武, Noriaki Takeda, Yuushi Okumura and Hiroshi Kido :
線毛上皮細胞より見出された新規膜結合型セリンプロテアーゼ,Serase-1の機能解析,
第26回日本耳鼻咽喉科免疫アレルギー学会, Feb. 2008.
84. Etsuhisa Takahashi, Yuushi Okumura, 潘 海燕 and Hiroshi Kido :
Functional analysis of a new member of the type II transmembrane serine proteases, MSPL/TMPRSS13,
第80回日本生化学会大会, Dec. 2007.
85. Yuushi Okumura, Etsuhisa Takahashi, 潘 海燕 and Hiroshi Kido :
II型膜結合型セリンプロテアーゼ,MSPL/TMPRSS13は塩基性アミノ酸の連続配列を認識し,特異的に切断する,
第80回日本生化学会大会, Dec. 2007.
86. Dai Mizuno, Tunetomo Takei, Maki Nisino, Wakako Shinahara, Takashi Kimoto, Akiho Fukuda and Hiroshi Kido :
SP-C is the essential component for the adjuvanticity of Surfacten.,
第30回日本分子生物学学会年会・第80回生化学会大会, Dec. 2007.
87. Tadashi Enomoto, Hiroshi Yamada, Junji Chida, Siye Wang and Hiroshi Kido :
Mechanism of augmentation of symptomatic of influenza virus infection by antipyretic, diclophenac.,
第30回 日本分子生物学会,第80回 日本生化学会大会, Dec. 2007.
88. Junji Chida, Tadashi Enomoto, Yuushi Ohnishi, Mariam Nasreen and Hiroshi Kido :
Down-regulation of mitochondrial related-genes by influenza virus infection and pathological role of them in multi-organ failure after virus infection.,
第30回 日本分子生物学会年会,第80回 日本生化学会大会, Dec. 2007.
89. 今城 純平, Masatake Akutagawa, Yohsuke Kinouchi, Fumio Shichijo and Hiroshi Kido :
Effect of Camitine Ingestion on EEG,
Journal of Shikoku-Section Joint Convention of the Institutes of Electrical and Related Engineers, 243, Sep. 2007.
90. Etsuhisa Takahashi, 端山 昌樹, 潘 海燕, Yuushi Okumura and Hiroshi Kido :
Ⅱ型膜結合型セリンプロテアーゼ,Polyserase-1の発現調節機構の解析,
第12回日本病態プロテアーゼ学会学術集会, Aug. 2007.
91. Junji Chida, Tadashi Enomoto, Miyoko Yamaguchi, Kiyotaka Okada and Hiroshi Kido :
プラスミノーゲン欠損マウスを用いたインフルエンザウイルスの増殖機構の解析,
第12回 病態と治療におけるプロテアーゼとインヒビター学会, Jun. 2007.
92. Junpei Imajo, Masatake Akutagawa, Yohsuke Kinouchi, Fumio Shichijo and Hiroshi Kido :
脳波におけるカルニチンの効果に関する研究,
Journal of Shikoku-Section Joint Convention of the Institutes of Electrical and Related Engineers, 182, Sep. 2006.
93. Etsuhisa Takahashi, 島袋 陽, 端山 昌樹, Yuushi Okumura and Hiroshi Kido :
新規II型膜結合型セリンプロテアーゼ,Serase-1Bの生理機能解析,
第11回病態と治療におけるプロテアーゼとインヒビター研究会, Aug. 2006.
94. 島袋 陽, Etsuhisa Takahashi, 端山 昌樹, Yuushi Okumura and Hiroshi Kido :
II型膜結合型セリンプロテアーゼ・mouse serase-1Bの発現解析,
第11回病態と治療におけるプロテアーゼとインヒビター研究会, Aug. 2006.
95. 端山 昌樹, Yuushi Okumura, Etsuhisa Takahashi, 島袋 陽, 田村 学, Noriaki Takeda, 久保 武 and Hiroshi Kido :
Transcriptional regulation of a novel transmembrane serine protease, Serase-1.,
第78回日本生化学会大会, Oct. 2005.
96. Yuushi Okumura, 端山 昌樹, Etsuhisa Takahashi, 島袋 陽 and Hiroshi Kido :
Serase-1, a new splice variant of Polyserase-1/TMPRSS9, is an activator of pro-urokinase and is involved in urokinase/plasmin-mediated proteolysis.,
第78回日本生化学会大会, Oct. 2005.
97. 端山 昌樹, Yuushi Okumura, Etsuhisa Takahashi, 島袋 陽 and Hiroshi Kido :
新規膜結合型セリンプロテアーゼ,Serase-1の機能解析,
第10回病態と治療におけるプロテアーゼとインヒビター研究会, Aug. 2005.
98. Yuushi Okumura, 端山 昌樹, Etsuhisa Takahashi and Hiroshi Kido :
線毛上皮細胞に高発現する新規膜結合型セリンプロテアーゼ,Serase-1の機能解析,
第46回日本生化学会中国四国支部例会, May 2005.
99. 端山 昌樹, Yuushi Okumura, 田村 学, 田村 潤子, 織名 崇, Noriaki Takeda, Hiroshi Kido and 久保 武 :
線毛上皮細胞より見出された新規膜結合セリンプロテアーゼ,Serase-1の機能解析,
第23回日本耳鼻咽喉科免疫アレルキ ー学会, 2005.
100. 端山 昌樹, Yuushi Okumura, Etsuhisa Takahashi, 藤内 美恵子, Noriaki Takeda, 田村 学, 久保 武 and Hiroshi Kido :
新規膜結合型セリンプロテアーゼ,Serase-1の気道線毛細胞での選択的局在はFoxJ1によって転写制御されている,
第27回日本分子生物学会年会, Dec. 2004.
101. Yuushi Okumura, 端山 昌樹, Etsuhisa Takahashi, 藤内 美恵子 and Hiroshi Kido :
Serase-1, a new member of the type II transmembrane serine protease, is highly expressed in ciliated epithelial cells.,
第77回日本生化学会大会, Oct. 2004.
102. Dai Mizuno, 井手 美喜子, 一宮 智子, 久保 いつか and Hiroshi Kido :
経鼻ワクチンの気道粘膜IgA誘導におけるサーファクタントプロテインB, Cおよび脂質成分のアジュバント効果,
第77回日本生化学会, Oct. 2004.
103. Yuushi Okumura, 端山 昌樹, Etsuhisa Takahashi, 藤内 美恵子 and Hiroshi Kido :
新規膜結合型セリンプロテアーゼ,Serase-1の気道線毛細胞での選択的局在,
第9回病態と治療におけるプロテアーゼとインヒビター研究会, Jul. 2004.
104. Yuushi Okumura, 端山 昌樹, Etsuhisa Takahashi, 藤内 美恵子 and Hiroshi Kido :
線毛上皮細胞に特異的に発現する新規膜結合型セリンプロテアーゼの性状とその役割,
第45回日本生化学会中国四国支部例会, May 2004.
105. Yuushi Okumura, 藤内 美恵子, Etsuhisa Takahashi and Hiroshi Kido :
TMPRSS7, a new member of the type II transmembrane serine protease, has kallikrein-like characteristics.,
第76回日本生化学会大会, Oct. 2003.
106. Miwa Bando, 山下 大, Hiroshi Kido, Akihiko Tsuji and Yoshiko Matsuda :
巨核球分化におけるプロセシングプロテアーゼPACE4とfurinの転写調節機構,
Seikagaku, Vol.74, No.8, 1016, Oct. 2002.
107. 村田 英子, Saimoon Sharmin, Hiroshi Shiota and Hiroshi Kido :
粘液プロテアーゼインヒビターの抗アレルギー作用についての検討,
Acta Societatis Ophthalmologicae Japonicae, Vol.106, 106, May 2002.

Et cetera, Workshop:

1. Masatake Akutagawa, Imajo Jumpei, Yohsuke Kinouchi, Fumio Shichijo and Hiroshi Kido :
Effect of L-carnitine ingestion on brain activity, --- In the view of EEG analysis ---,
IEICE Technical Report, Vol.108, No.126, 31-34, Jul. 2008.
2. 端山 昌樹, Yuushi Okumura, Hiroshi Kido, 田村 学, 久保 武 and Noriaki Takeda :
線毛上皮細胞より見いだされた新規膜結合型セリンプロテアーゼ,Serase-1の機能解析,
第6回中四国耳鼻咽喉科アレルギー研究会, Jul. 2005.
3. 端山 昌樹, Yuushi Okumura, Hiroshi Kido, 田村 学, 久保 武 and Noriaki Takeda :
線毛上皮細胞より見出された新規膜結合セリンプロテアーゼ,Serase-1の機能解析,
第6回中四国耳鼻咽喉科アレルギー研究会, 2005.

Report:

1. Masayuki Shibuya, Hiroshi Kido, Yoshio Hayashi, Hisao Nemoto, Shigeki Sano, Koji Yasutomo, Hiroyuki Azuma, Yasuhiko Nishioka, Junji Terao, Takeshi Nikawa, Hiroaki Misawa, Shigeki Matsuo, Yoshinobu Baba, Kozo Matsumoto, Hirokazu Miyoshi and Saburo Sone :
徳島大学先端医療開発研究センター設置準備室成果報告書,
Dec. 2002.

Patent:

1. Hiroshi Kido and Dai Mizuno : IgA抗体の選択的産生からIgA及びIgG両抗体産生への切替えを可能にする抗原薬物ビークルとこれを用いる経鼻・粘膜ワクチン., 2005-227504, .
2. Hiroshi Kido and Dai Mizuno : 粘膜免疫,その感作剤を用いる粘膜ワクチン及び予防接種システム., 2004-238264, .
3. Hiroshi Kido and Dai Mizuno : 安全かつ有効な粘膜免疫の誘導,粘膜ワクチン,及び経粘膜・経皮ドラッグデリバリーシステム (DDS) の確立., 2004-125036, .
4. 石田 晃彦, 花田 祐紀, Hiroshi Kido, Junji Chida, 谷 博文 and 渡慶次 学 : 血液検体のATP測定方法及びキット, 2013-174874 (Aug. 2013), 2015-42156 (Mar. 2015), 2013-174874 (Aug. 2013).
5. 大村 智, 山地 賢三郎, 山本 剛, Hiroshi Kido, Kazuhiko Yamane, 砂塚 敏明 and 廣瀬 友靖 : PDK4阻害剤及びその応用, (Dec. 2012), WO2014/103321 A1 (Jul. 2014), PCT/JP2013/007649 (Dec. 2013).
6. Hiroshi Kido, Dai Mizuno, Tunetomo Takei, 上田 博嗣, 吉川 浩司, 大隅 恵介, 山本 伸行 and 周藤 健治 : RSV粘膜ワクチン, 2011-185873 (Aug. 2012), WO2013/031827 (Mar. 2013), PCT/JP2012/071831 (Aug. 2012).
7. Hiroshi Kido, Junji Chida, 山根 一彦, 大村 智, 中野 洋文, 山地 賢三郎 and 山本 剛 : PDK4阻害剤及びその利用, (Apr. 2012), WO2013/153821 A1 (Oct. 2013), PCT/JP2013/002500 (Apr. 2013).
8. Hiroshi Kido, Masaji Nishimura and Junji Chida : 病気の重症度の検査方法, PCT/JP2011/002979 (May 2011), WO2011/152012 A1 (Dec. 2011), 2010-125354 (May 2010).
9. Hiroshi Kido, Junji Chida, 塙 雅明, 山本 善一, 井 紀孝 and 角田 健司 : インフルエンザの治療剤または予防剤, 2011-15729 (Jan. 2011), WO2012/101846 (Aug. 2012), PCT/JP2011/067321 (Jul. 2011).
10. Hiroshi Kido, 多田 仁美 and 澤淵 貴子 : --, (Jun. 2010), (Jun. 2011), 2010-129694 (Jun. 2010).
11. Hiroshi Kido : 粘膜ワクチン, (Mar. 2010), (Mar. 2011), 2010-045205 (Mar. 2010).
12. Hiroshi Kido and 鈴木 宏一 : 乳幼児のアレルギー発症の予測・アレルギーの増悪,改善の判定法, (Oct. 2009), (Nov. 2010), 2009-250098 (Oct. 2009).
13. Hiroshi Kido and 鈴木 宏一 : -, (Sep. 2009), (Sep. 2010), 2009-503895 (Sep. 2009).
14. Hiroshi Kido and 寺島 薫 : インフルエンザ罹患リスクの予測方法, (Aug. 2009), (Sep. 2010), 12/461,983, 09011204,6 (Aug. 2009).
15. Hiroshi Kido, 武井 恒知 and 水野 大 : 合成ペプチドを含有する抗原薬物ビークルとこれを用いる粘膜ワクチン, (Mar. 2009), (Apr. 2010), PCT/JP2009/0565608 (Mar. 2009).
16. Hiroshi Kido, Junji Chida and 武井 恒知 : ヌクレオチドの抽出方法, PCT/JP2009/51364 (Jan. 2009), WO 2009/096429 A1 (Aug. 2009), 2008-017863 (Jan. 2008).
17. Hiroshi Kido, Mineyoshi Hiyoshi, Miwa Bando, 木下 盛敏, 福田 陽司 and 水口 寛 : トランスクリプションチップ, 2003-138395 (May 2003), WO 2004/101784 A1 (Nov. 2004), PCT/JP2004/006796 (May 2004).

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • Allergy research prospect with new paradigm open up by the new sensitive allergen microarray (Project/Area Number: 17K19662 )
  • Study on the pathogenesis of severe influenza virus infection associated with cytokine storm and its effective treatment options (Project/Area Number: 16H05348 )
  • Discovery of antigen-specific low affinity IgE in cord blood and the mechanisms of affinity maturation after birth for prevention of allergy (Project/Area Number: 15K15371 )
  • Screening of Flu Alarmin biomarkers of severe influenza virus infection and their confirmation in animal model (Project/Area Number: 25670466 )
  • The application to cancer vaccine of SSF that mimics pulmonary surfactant (Project/Area Number: 24500527 )
  • Pathogenicity of multiple organ failure induced by seasonal and highly pathogenic avian influenza virus infection and its therapeutic options (Project/Area Number: 24249059 )
  • Studies on real-time biomarker of illness severity inthe patients of critical illness and development of the diagnosis machine (Project/Area Number: 23659846 )
  • The analysis of host response determining the severe influenza and HIV infection. (Project/Area Number: 23591477 )
  • 乳幼児食物アレルギーの診断と予防を可能にする臍帯血高感度診断デバイスの開発研究 (Project/Area Number: 21659245 )
  • Development of new therapeutics for a highly pathogenic influenza virus infection by inhibition of virus entry and multiplication (Project/Area Number: 21249061 )
  • The chemical biology of low side effects compound in anti-fever drugs, which is derived from the analysis about fatal function by diclofenac. (Project/Area Number: 20611013 )
  • 食物アレルギーを血液と唾液から総合的に診断する新規ハイスループットデバイスの開発 (Project/Area Number: 19659253 )
  • ハイスループット食物アレルゲンエピトープ解析ダイヤモンドコーティングチップの開発 (Project/Area Number: 18659293 )
  • The role of anti-apoptotic factor 14-3-3 in HIV-1-associated dementia (HAD) pathology : The implication for the therapy (Project/Area Number: 17591044 )
  • Mechanism of encephalitis after influenza virus infection based on defect of β-oxidation in liver (Project/Area Number: 15590942 )
  • The relationship between a molecular chaperone and protease : The discovery of NDP kinase like activity of a chaperone, and degeneration diseases. (Project/Area Number: 14570121 )
  • 新規生理活性物質・エンドセリン(1-31)の意外な顆粒球・好酸球ケモカイン作用 (Project/Area Number: 13878119 )
  • Functional analysis of substrate-aggregation inhibition and unfoldase activities in the 20S proteasome (Project/Area Number: 13680717 )
  • Development of new influenza virus treatments based an the findings of triggering proteases for influenza virus entry into the cells and on the findings of protease-activating receptors (Project/Area Number: 13557014 )
  • Molecular chaperone activity of the 20S proteasome : Inhibitory activity of the substrate protein aggregation and unflodase activity (Project/Area Number: 13470026 )
  • 高感度赤外線蛍光内視鏡を用いた微小癌診断法の開発 (Project/Area Number: 13218088 )
  • 生体内新規鍵物質エンドセリン(1-31)の生理機能:ケモカイン作用と未梢循環制御 (Project/Area Number: 13024258 )
  • ATP依存性立体構造変異蛋白群に内在するシャペロン型NDPK活性の発見と変異機序 (Project/Area Number: 12877022 )
  • The basic study concerning the high pregnancy rate by in vitro fertilization-embryo transfer treatment in infertile women with antisperm antibody (Project/Area Number: 12671606 )
  • Development of an immunocontraceptive DNA vaccine using sperm (Project/Area Number: 12557137 )
  • Pathophysiological role of ET-1(1-31) on the inflammatory diseases. (Project/Area Number: 12557008 )
  • 赤外線蛍光内視鏡を用いた微小癌診断法の開発 (Project/Area Number: 12217100 )
  • 癌細胞膜上のMMP9前躯体新規活性化機構の発見と癌細胞浸潤機序の解析 (Project/Area Number: 12215112 )
  • 新規生理活性物質エンドセリン(1-31)の発見とその意外な新生理機能 (Project/Area Number: 12045251 )
  • 新規生理活性物質エンドセリン(1-31)の発見と新生理機能の解析 (Project/Area Number: 11877022 )
  • Mutations of the core gene sequence of HCV from patients with hepatocellular carcinoma in China and Japan (Project/Area Number: 11695087 )
  • The studies on the sugar chain structures of rat cathepsin J (C) and its functions. (Project/Area Number: 11680607 )
  • Discovery of chaperone-type nucleoside diphosphate kinase, a novel function of molecular chaperone proteins, and role of the activity in proteolysis (Project/Area Number: 11670128 )
  • Discovery of chaperone-type nucleoside diphosphate kinase activity in Hsp70 and proteasome and its pathophysiological function in these proteins (Project/Area Number: 11470043 )
  • Role of newly discovered endothelin-1(1-31) on renal injury (Project/Area Number: 10670085 )
  • Discovery of the potentiating proteases for influenza virus infection and their inhibitors as defensive compounds (Project/Area Number: 10557033 )
  • 新しい分子シャペロン蛋白質機能、NDP キナーゼ活性の発見と作用機構の解析 (Project/Area Number: 10172221 )
  • 癌転移・浸潤にかかわる膜結合型MMP前駆体活性化酵素の発見と作用機序の解析 (Project/Area Number: 10152244 )
  • Regulation and Physiological Roles of Human Tryptase in the Secretary Granules of Mast Cells (Project/Area Number: 09680624 )
  • Hormonal regulation of production and activation of immunoglobulin binding factor. (Project/Area Number: 09671686 )
  • Novel bioactive endothelins (1-31) produced by chymase and their physiological functions (Project/Area Number: 09670130 )
  • 新しい分子シャペロン蛋白機能の発見とこれによる基質との動的相互作用 (Project/Area Number: 09276220 )
  • Medical use of protease inhibitors for virus infection (Project/Area Number: 09044314 )
  • キマ-ゼの形成する新しいエンドセリン誘導体の血管と気管支平滑筋収縮作用の解析 (Project/Area Number: 08878101 )
  • IDENTIFICATION OF NEW GLOMERULAR PROGRESSION FACTORS USING MONOCLONAL ANTIBODY (Project/Area Number: 08670894 )
  • Development of novel diagnosis method for minutecancer by infrared fluorescence endoscopy using fluorescence-emitting antibody by infrared ray excitation. (Project/Area Number: 08457168 )
  • Mechanism of Selective Degradation of Proteins (Project/Area Number: 08278102 )
  • ウイルスと細胞との膜融合を誘発する細胞性プロテアーゼの発見とその制御因子の解析 (Project/Area Number: 07670175 )
  • バイオモジュレーターとしてのプロテアーゼ (Project/Area Number: 07358024 )
  • エイズの病態と制御に関する基礎研究 柱1.HIVの複製機構 (Project/Area Number: 07277104 )
  • 細胞増殖の制御とプロテアーゼ (Project/Area Number: 07273107 )
  • B型肝炎ウイルスX蛋白質と結合する肝細胞内プロテアーゼの機能変化と発癌機序の解析 (Project/Area Number: 07272229 )
  • Virus activation by tryptase and its inhibition in vivo (Project/Area Number: 07044275 )
  • 細胞増殖の制御とプロテアーゼ (Project/Area Number: 06281114 )
  • B型肝炎ウイルスX蛋白質と結合する肝細胞内プロテアーゼの機能変化と発癌機序の解析 (Project/Area Number: 06280220 )
  • HIVのTリンパ球への結合と膜融合に関与するT細胞内プロテアーゼの作用機序 (Project/Area Number: 06255209 )
  • インフルエンザウイルスの感染性を決定する宿主細胞プロテアーゼの発見と作用機序 (Project/Area Number: 05670146 )
  • Isolation of the cellular protease that determines infectious tropism of influenza virus in human and inhibition of the infection by the protease inhibitor from human bronchial lavage (Project/Area Number: 05557014 )
  • エイズウイルスの感染性と複製に関与するT細胞内プロテアーゼ群の作用機序の解析 (Project/Area Number: 05262209 )
  • 細胞増殖の制御とプロテアーゼ (Project/Area Number: 05151061 )
  • 糖鎖構造をモデルにしたカテプシンLの細胞内選別輸送の分子機構 (Project/Area Number: 04807019 )
  • Tリンパ球へのエイズウイルス感染におけるトリプシン型ブロテアーゼ群関与の分子機構 (Project/Area Number: 04269207 )
  • Purification of processing protease for retroviral envelope glycoprotein and role of it in the process of retroviral infection (Project/Area Number: 03454162 )
  • Tリンパ球へのエイズウイルス感染機構におけるトリプシン型プロテア-ゼの関与 (Project/Area Number: 03219210 )
  • レトロウイルス外膜蛋白活性化プロテア-ゼの発見と、その阻害剤による感染阻止 (Project/Area Number: 03152090 )
  • アルツハイマ-病アミロイド前駆蛋白の局在ならびに生物機能 (Project/Area Number: 02807033 )
  • An approach for development of new drugs for AIDS which inhibit the novel receptor for AIDS virus (Project/Area Number: 02557018 )
  • A novel membrane-bound serine protease in human T4^+-lymphocyte -possible receptor for HIV gp120- (Project/Area Number: 02404026 )
  • Tリンパ球へのエイズウイルス感染機構におけるトリプシン型プロテア-ゼの関与 (Project/Area Number: 02235209 )
  • Tリンパ球へのエイズウイルス感染機構におけるトリプシン型プロテア-ゼの関与 (Project/Area Number: 01653505 )
  • グルココルチコイド作用増強物質によるリンパ性白血病の新治療法の開発 (Project/Area Number: 01614526 )
  • グルココルチコイド作用発現におけるプロテインキナ-ゼCの役割 (Project/Area Number: 01570136 )
  • グルココルチコイド作用増強物質によるリンパ性白血病の新治療法の開発 (Project/Area Number: 63614525 )
  • Synthesis and large production of glucocorticoid action enhancers and development of new steroid therapy. (Project/Area Number: 62870016 )
  • グルココルチコイド作用増強物質によるリンパ性白血病の新治療法の開発 (Project/Area Number: 62614526 )
  • Effects of chymase on limited proteolysis and activation of protein kinase on the mechanism of degranulation from mast cells (Project/Area Number: 62570113 )
  • γ-グルタミントランスペプチダーゼのProcessing Proteaseの追求 (Project/Area Number: 61580170 )
  • 肥満細胞のヒスタミン顆粒に局在するキマーゼとトリプターゼの細胞生理的役割 (Project/Area Number: 61570126 )
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