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Tokushima University > Graduate School of Biomedical Sciences > 歯学域 > Oral Science > Basic Dentistry > Department of Oral Microbiology >
Tokushima University > Research Clusters > Research Clusters (Selected) > 1804002 抗菌薬の適正使用に寄与する薬剤耐性菌の耐性分子機序解析 >
Tokushima University > Faculty of Dentistry > Course in Dentistry > Basic Oral Sciences > Oral Microbiology >
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Research Activity

Field of Study

Periodontology

Subject of Study

歯周病と糖尿病に関する研究

Book / Paper

Academic Paper (Judged Full Paper):

1. Takenori Yamamoto, Mizune Ozono, Akira Watanabe, Kosuke Maeda, Atsushi Nara, Mei Hashida, Yusuke Ido, Yuka Hiroshima, Akiko Yamada, Hiroshi Terada and Yasuo Shinohara :
Functional analysis of coiled-coil domains of MCU in mitochondrial calcium uptake,
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 148061, 2019.
(DOI: 10.1016/j.bbabio.2019.148061,   PubMed: 31394096)
2. Takenori Yamamoto, Moe Tsunoda, Mizune Ozono, Akira Watanabe, Kazumasa Kotake, Yuka Hiroshima, Akiko Yamada, Hiroshi Terada and Yasuo Shinohara :
Polyethyleneimine renders mitochondrial membranes permeable by interacting with negatively charged phospholipids in them,
Archives of Biochemistry and Biophysics, 2018.
(DOI: 10.1016/j.abb.2018.06.003,   PubMed: 29886045)
3. Satoshi Fujita, Masaki Suyama, Kenji Matsumoto, Atsushi Yamamoto, Takenori Yamamoto, Yuka Hiroshima, Takayuki Iwata, Arihiro Kano, Yasuo Shinohara and Mitsuru Shindo :
Synthesis and evaluation of simplified functionalized bongkrekic acid analogs.,
Tetrahedron, Vol.74, No.9, 962-969, 2018.
(DOI: 10.1016/j.tet.2018.01.018,   Elsevier: Scopus)
4. Yuka Hiroshima, Takenori Yamamoto, Masahiro Watanabe, Yoshinobu Baba and Yasuo Shinohara :
Effects of cold exposure on metabolites in brown adipose tissue of rats.,
Molecular Genetics and Metabolism Reports, Vol.15, 36-42, 2018.
(DOI: 10.1016/j.ymgmr.2018.01.005,   PubMed: 30023288)
5. Yuka Hiroshima, Eijiro Sakamoto, Kaya Yoshida, Kaori Abe, Koji Naruishi, Takenori Yamamoto, Yasuo Shinohara, Jun-ichi Kido and Carolyn L Geczy :
Advanced glycation end-products and Porphyromonas gingivalis lipopolysaccharide increase calprotectin expression in human gingival epithelial cells.,
Journal of Cellular Biochemistry, Vol.119, No.2, 1591-1603, 2018.
(DOI: 10.1002/jcb.26319,   PubMed: 28771806)
6. Kaya Yoshida, Hirohiko Okamura, Yuka Hiroshima, Kaori Abe, Jun-ichi Kido, Yasuo Shinohara and Kazumi Ozaki :
PKR induces the expression of NLRP3 by regulating the NF-κB pathway in Porphyromonas gingivalis-infected osteoblasts,
Experimental Cell Research, Vol.354, No.1, 57-64, 2017.
(Tokushima University Institutional Repository: 111349,   DOI: 10.1016/j.yexcr.2017.03.028,   PubMed: 28341446)
7. Yuka Hiroshima, Kenneth Hsu, Nicodemus Tedla, Sze Wing Wong, Sharron Chow, Naomi Kawaguchi and Carolyn L Geczy :
S100A8/A9 and S100A9 reduce acute lung injury.,
Immunology and Cell Biology, Vol.95, No.5, 461-472, 2017.
(DOI: 10.1038/icb.2017.2,   PubMed: 28074060)
8. Hiroshi Ito, Yukihiro Numabe, Shuichi Hashimoto, Satoshi Sekino, Etsuko Murakashi, Hitomi Ishiguro, Daisuke Sasaki, Takashi Yaegashi, Hideki Takai, Masaru Mezawa, Yorimasa Ogata, Hisashi Watanabe, Satsuki Hagiwara, Yuichi Izumi, Yuka Hiroshima, Jun-ichi Kido, Toshihiko Nagata and Kazushi Kunimatsu :
Correlation Between Gingival Crevicular Fluid Hemoglobin Content and Periodontal Clinical Parameters.,
Journal of Periodontology, Vol.87, No.11, 1314-1319, 2016.
(DOI: 10.1902/jop.2016.160092,   PubMed: 27468797)
9. Jun-ichi Kido, Yukiko Bandou, Mika Bandou, Yukari Kajiura, Yuka Hiroshima, Yuji Inagaki, Hiromi Murata, Takahisa Ikuta, Reiko Kido, Koji Naruishi, Makoto Funaki and Toshihiko Nagata :
YKL-40 level in gingival crevicular fluid from patients with periodontitis and type 2 diabetes,
Oral Diseases, Vol.21, No.5, 667-673, 2015.
(DOI: 10.1111/odi.12334,   PubMed: 25740558,   Elsevier: Scopus)
10. Yuka Hiroshima, Linda Garthwaite, Kenneth Hsu, Hyouna Yoo, Sang-Ho Park, L Carolyn Geczy, K Rakesh Kumar and Cristan Herbert :
ISU201 enhances the resolution of airway inflammation in a mouse model of an acute exacerbation of asthma.,
Mediators of Inflammation, Vol.2015, 405629, 2015.
(DOI: 10.1155/2015/405629,   PubMed: 25767333,   Elsevier: Scopus)
11. Yuka Hiroshima, Mika Bandou, Yuji Inagaki, Reiko Kido, Masatoshi Kataoka, Toshihiko Nagata and Jun-ichi Kido :
Effect of Hangeshashinto on calprotectin expression in human oral epithelial cells.,
Odontology, Vol.104, 152-162, 2015.
(DOI: 10.1007/s10266-015-0196-3,   PubMed: 25649126)
12. Javkhlan Purevjav, Xu Guangfei, Chen Gang, Chenjuan Yao, Yuka Hiroshima, Hiroshi Yoshimura, Toshihiko Nagata and Kazuo Hosoi :
Expression and LPS-Induced Elevation of Nod2 and Calprotectin in the Submandibular Gland of Wild-Type and TLR4-Knockout Male Mice,
Journal of Research and Practice in Dentistry, Vol.2015, No.290259, 2015.
(DOI: 10.5171/2015.290259)
13. Hiroshi Ito, Yukihiro Numabe, Satoshi Sekino, Etsuko Murakashi, Hitomi Iguchi, Shuichi Hashimoto, Daisuke Sasaki, Takashi Yaegashi, Kazushi Kunimatsu, Hideki Takai, Masaru Mezawa, Yorimasa Ogata, Hisashi Watanabe, Satsuki Hagiwara, Yuichi Izumi, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
Evaluation of bleeding on probing and gingival crevicular fluid enzyme activity for detection of periodontally active sites during supportive periodontal therapy,
Odontology, Vol.102, No.1, 50-56, 2014.
(DOI: 10.1007/s10266-012-0090-1,   PubMed: 23179356,   Elsevier: Scopus)
14. Yuka Hiroshima, Kenneth Hsu, Nicodemus Tedla, Ming Yuen Chung, Sharron Chow, Cristan Herbert and L Carolyn Geczy :
S100A8 induces IL-10 and protects against acute lung injury.,
The Journal of Immunology, Vol.192, No.6, 2800-2811, 2014.
(DOI: 10.4049/jimmunol.1302556,   PubMed: 24532576)
15. L Carolyn Geczy, Ming Yuen Chung and Yuka Hiroshima :
Calgranulins may contribute vascular protection in atherogenesis.,
Circulation Journal, Vol.78, No.2, 271-280, 2013.
(DOI: 10.1253/circj.CJ-13-1505,   PubMed: 24389598)
16. Mika Bandou, Xianqiong Zou, Yuka Hiroshima, Masatoshi Kataoka, Karen F. Ross, Yasuo Shinohara, Toshihiko Nagata, Mark C. Herzberg and Jun-ichi Kido :
Mechanism of interleukin-1α transcriptional regulation of S100A9 in a human epidermal keratinocyte cell line,
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Vol.1829, No.9, 954-962, 2013.
(DOI: 10.1016/j.bbagrm.2013.03.010,   PubMed: 23563247,   Elsevier: Scopus)
17. Kaori Abe, Y Hashimoto, S Yatsushiro, S Yamamura, Mika Bandou, Yuka Hiroshima, Jun-ichi Kido, M Tanaka, Yasuo Shinohara, Toshihiko Ooie, Yoshinobu Baba and Masatoshi Kataoka :
Simultaneous immunoassay analysis of plasma IL-6 and TNF-α on a microchip.,
PLoS ONE, Vol.8, No.1, e53620, 2013.
(DOI: 10.1371/journal.pone.0053620,   PubMed: 23326472,   Elsevier: Scopus)
18. Yukiko Nakajima, Yuji Inagaki, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
Advanced glycation end-products enhance calcification in cultured rat dental pulp cells,
Journal of Endodontics, Vol.39, 873-878, 2013.
(DOI: 10.1016/j.joen.2012.11.027,   PubMed: 23791254,   Elsevier: Scopus)
19. Chie Mihara-Wada, 徳永 格, Hiroyuki Seto, Eijiro Sakamoto, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
Topical injection of osteoprotegerin prevents alveolar bone loss in rat experimental periodontitis,
Journal of the Japanese Association of Periodontology, Vol.54, No.2, 167-174, 2012.
(DOI: 10.2329/perio.54.167,   CiNii: 10030799485)
20. Jun-ichi Kido, Kaori Abe, Shouki Yatsushiro, Mika Bandou, Yuka Hiroshima, Toshihiko Nagata, Toshihiko Ooie, Masato Tanaka and Masatoshi Kataoka :
Determination of calprotectin in gingival crevicular fluid by immunoassay on a microchip,
Clinical Biochemistry, Vol.45, No.15, 1239-1244, 2012.
(DOI: 10.1016/j.clinbiochem.2012.05.009,   PubMed: 22609893)
21. Yuka Hiroshima, Mika Bandou, Yuji Inagaki, Chie Mihara-Wada, Masatoshi Kataoka, Hiromi Murata, Yasuo Shinohara, Toshihiko Nagata and Jun-ichi Kido :
Resistin in gingival crevicular fluid and induction of resistin release by Porphyromonas gingivalis lipopolysaccharide in human neutrophils,
Journal of Periodontal Research, Vol.47, No.5, 554-562, 2012.
(DOI: 10.1111/j.1600-0765.2011.01466.x,   PubMed: 22309231,   Elsevier: Scopus)
22. Jun-ichi Kido, Mika Bandou, Yuka Hiroshima, Hiroyuki Iwasaka, Keisuke Yamada, Naoto Ohgami, Toshiyuki Namubu, Masatoshi Kataoka, Takenori Yamamoto, Yasuo Shinohara, Ikuko Sagawa and Toshihiko Nagata :
Analysis of proteins in human gingival crevicular fluid by mass spectrometry,
Journal of Periodontal Research, Vol.47, No.4, 488-499, 2012.
(DOI: 10.1111/j.1600-0765.2011.01458.x,   PubMed: 22220998)
23. Jun-ichi Kido, Mami Hino, Mika Bandou and Yuka Hiroshima :
Diagnosis of periodontal diseases by biomarkers,
Electrical Engineering in Japan, Vol.179, No.1, 40-45, 2012.
(DOI: 10.1002/eej.21150)
24. Purevjav Javkhlan, Yuka Hiroshima, Ahmad Azlina, Takahiro Hasegawa, Chenjuan Yao, Tetsuya Akamatsu, Jun-ichi Kido, Toshihiko Nagata and Kazuo Hosoi :
Lipopolysaccharide-mediated induction of calprotectin in the submandibular and parotid glands of mice,
Inflammation, Vol.34, No.6, 668-680, 2011.
(DOI: 10.1007/s10753-010-9277-1,   PubMed: 21125321)
25. Yuka Hiroshima, Mika Bandou, Masatoshi Kataoka, Yuji Inagaki, Mark C. Herzberg, Karen F. Ross, Kazuo Hosoi, Toshihiko Nagata and Jun-ichi Kido :
Regulation of antimicrobial peptide expression in human gingival keratinocytes by interleukin-1α,
Archives of Oral Biology, Vol.56, No.8, 761-767, 2011.
(DOI: 10.1016/j.archoralbio.2011.01.004,   PubMed: 21316034)
26. Ahmad Azlina, Purevjav Javkhlan, Yuka Hiroshima, Takahiro Hasegawa, Chenjuan Yao, Tetsuya Akamatsu and Kazuo Hosoi :
Roles of lysosomal proteolytic systems in AQP5 degradation in the submandibular gland of rats following chorda tympani parasympathetic denervation,
American Journal of Physiology, Gastrointestinal and Liver Physiology, Vol.299, No.5, G1106-G1117, 2010.
(DOI: 10.1152/ajpgi.00194.2010,   PubMed: 20689061)
27. Yuji Inagaki, Mika Bandou, 中島 由紀子, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
Osmotic Stress Affects Calcium Deposition and Osteopontin Expression in Cultured Rat Dental Pulp Cells,
The Japanese Journal of Conservative Dentistry, Vol.53, No.4, 367-375, 2010.
(CiNii: 110008006906)
28. Yuka Hiroshima, Mika Bandou, Masatoshi Kataoka, Yasuo Shinohara, MC Herzberg, KF Ross, Yuji Inagaki, Toshihiko Nagata and Jun-ichi Kido :
Shosaikoto increases calprotectin expression in human oral epithelial cells.,
Journal of Periodontal Research, Vol.45, No.1, 79-86, 2010.
(DOI: 10.1111/j.1600-0765.2009.01203.x,   PubMed: 19602113)
29. Mika Bandou, Yuka Hiroshima, Masatoshi Kataoka, MC Herzberg, KF Ross, Yasuo Shinohara, Takenori Yamamoto, Toshihiko Nagata and Jun-ichi Kido :
Modulation of calprotectin in human keratinocytes by keratinocyte growth factor and interleukin-1alpha.,
Immunology and Cell Biology, Vol.88, No.3, 328-333, 2010.
(DOI: 10.1038/icb.2009.104,   PubMed: 20065999)
30. Jun-ichi Kido, 日野 真美, Mika Bandou and Yuka Hiroshima :
バイオマーカーを用いた歯周病診断,
IEEJ Transactions on Electronics, Information and Systems, Vol.129, No.2, 233-237, 2009.
(DOI: 10.1541/ieejeiss.129.233,   CiNii: 10023999637)
31. Yuka Hiroshima, Yuji Inagaki, Mika Bandou, Jun-ichi Kido and Toshihiko Nagata :
Long-term Observation of Marked Overfilling in Root Canal Therapy : A Report of Three Cases,
The Japanese Journal of Conservative Dentistry, Vol.51, No.5, 485-492, 2008.
(CiNii: 110007151262)
32. Yuka Hiroshima, Mika Bandou, Masatoshi Kataoka, Toshihiko Nagata and Jun-ichi Kido :
Regulation of calprotectin expression in human keratinocytes in vitro,
Journal of the Japanese Association of Periodontology, Vol.49, No.3, 224-232, 2007.
(DOI: 10.2329/perio.49.224,   CiNii: 10027094494)
33. Mika Bandou, Yuka Hiroshima, Masatoshi Kataoka, Yasuo Shinohara, MC Herzberg, KF Ross, Toshihiko Nagata and Jun-ichi Kido :
Interleukin-1alpha regulates antimicrobial peptide expression in human keratinocytes.,
Immunology and Cell Biology, Vol.85, No.7, 532-537, 2007.
(DOI: 10.1038/sj.icb.7100078,   PubMed: 17549071)

Proceeding of International Conference:

1. E Sakamoto, Chie Mihara-Wada, K Tokunaga, H Seto and Yuka Hiroshima :
Topical application of osteoprotegerin inhibits alveolar bone loss in rat experimental periodontitis,
International Joint Symposium on Oral Science, Bali, Indonesia, Dec 17-19, 2010,
2. Yuka Hiroshima, Mika Bandou, Takahiro Hasegawa, Yuji Inagaki and Chie Mihara-Wada :
Resistin release from neutrophils is induced by Porphyromonas gingivalis lipopolysaccharide.,
IADR (International Association of Dental Research) Barcelona, Spain, July 14-17, 2010,
3. Yuka Hiroshima, Eijiro Sakamoto, Kaori Abe, Kaya Yoshida, Koji Naruishi, Toshihiko Nagata, Yasuo Shinohara, Geczy Carolyn and Jun-ichi Kido :
Advanced Glycation End-Products Increase Calprotectin in Human Gingival Epithelial Cells,
The 95th General Session & Exhibition of the International Association for Dental Research (IADR), San Francisco, Mar. 2017.
4. Yukiko Nakajima, Jun-ichi Kido, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Hiromi Murata and Toshihiko Nagata :
Effect of hypoxia on gene expression in human oral keratinocytes,
10th Asian Pacific Society of Periodontology Meeting, Nara, Sep. 2013.
5. Jun-ichi Kido, Mika Bandou, Yuji Inagaki, Yuka Hiroshima, Hiromi Murata, Chie Mihara-Wada, 梶浦 由加里, 生田 貴久, 篠原 宏貴, 橋本 万里, Yukiko Nakajima, Yukiko Bandou, Makoto Funaki, Haruhiko Saito and Toshihiko Nagata :
Diagnosis of diabetes-associated periodontitis using glycoalbumin and calprotectin in gingival crevicular fluid,
10th Asian Pacific Society of Periodontology Meeting, Nara, Sep. 2013.
6. Toshihiko Nagata, Jun-ichi Kido, Mika Bandou, Yuka Hiroshima, Yuji Inagaki, Hiromi Murata, Chie Mihara-Wada, Mika Bandou and Makoto Funaki :
Diagnosis of diabetes-associated periodontitis using biomarkers in gingival crevicular fluid,
91th General Session & Exhibition of the International Association for Dental Research. Seattle, USA, May 2013.
7. Yukiko Nakajima, Yuji Inagaki, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
AGE induces calcification and inflammatory factors in dental pulp tissues,
91th General Session & Exhibition of the International Accociation for Dental Research, Seattle, USA, May 2013.
8. Yukiko Nakajima, Yuji Inagaki, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
AGE induces calcification- and inflammation-related factors in dental pulp cells,
The 60th Annual Meeting of Japanese Association for Dental Research, Program and abstracts of papers, 92, Dec. 2012.
9. Toshihiko Nagata, Jun-ichi Kido, Mika Bandou, Yuka Hiroshima, Yuji Inagaki, Masami Ninomiya, Chie Mihara-Wada, Hiromi Murata, Yukiko Bandou and Makoto Funaki :
Diagnosis of diabetes-associated periodontitis by measuring biomarkers in gingival crevicular fluid,
The 9th International Diabetes Federation Western Pacific Region Congress/ The 4th AASD Scientific Meeting, Nov. 2012.
10. Yukiko Nakajima, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
Advanced glycation end-product increase calcification and inflammatory factors in cultured rat dental pulp cells,
European Calcified Tissue Society, 39th Annual Congress Final programme, 73, Stockholm (Sweden), May 2012.
11. Yuji Inagaki, Yukiko Nakajima, Mika Bandou, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
Relationship between pathologic calcification and osteopontin expression in dental pulp tissues of diabetic rats,
European Calcified Tissue Society, 39th Annual Congress, Final Programme, 125, Stockholm (Sweden), May 2012.
12. Purevjav Javkhlan, Yuka Hiroshima, Azlina Ahmad, Takahiro Hasegawa, Chenjuan Yao, Tetsuya Akamatsu, Jun-ichi Kido, Toshihiko Nagata and Kazuo Hosoi :
Induction of calprotectin mRNAs by lipopolysaccharide in the salivary gland of mice,
The Journal of Medical Investigation : JMI, Vol.56, No.Suppl, 287-289, Tokushima, Dec. 2009.
(Tokushima University Institutional Repository: 111354,   DOI: 10.2152/jmi.56.287,   PubMed: 20224205)

Proceeding of Domestic Conference:

1. Yuka Hiroshima, Jun-ichi Kido, 木戸 理恵, Kaya Yoshida, Yuji Inagaki, Koji Naruishi and Hiromichi Yumoto :
オーラルケアへの応用を目指した抗菌ペプチド合成とリポソーム封入,
第62回秋季日本歯周病学会学術大会, Oct. 2019.
2. Rie Kido, Yuka Hiroshima, Takahisa Ikuta, Kaya Yoshida, Yuji Inagaki, Koji Naruishi, Kazumi Ozaki, Jun-ichi Kido and Hiromichi Yumoto :
最終糖化産物はヒト口腔上皮細胞のリポカリン2発現を増加する,
第62回春季日本歯周病学会学術大会, May 2019.
3. Yuka Hiroshima :
生体抗菌ペプチドの動態と歯周病予防への応用の可能性,
第61回秋季日本歯周病学会学術大会, Oct. 2018.
4. Takenori Yamamoto, Tsunoda Moe, Akira Watanabe, Mizune Ohzono, 井戸 佑介, Yuka Hiroshima, Akiko Yamada, 寺田 弘 and 篠原 康雄 :
ポリエチレンイミンがミトコンドリアからの シトクロムc漏出を誘起するメカニズム,
第40回生体膜と薬物の相互作用シンポジウム, Oct. 2018.
5. 高木 亮輔, Eijiro Sakamoto, Yuji Inagaki, Yuka Hiroshima, Koji Naruishi, Jun-ichi Kido and Hiromichi Yumoto :
カルプロテクチンはマウス骨細胞の炎症および骨代謝関連因子の発現を制御する,
第61回春季日本歯周病学会学術大会, Jun. 2018.
6. Ryosuke Takagi, Eijiro Sakamoto, Yuji Inagaki, Yuka Hiroshima, Koji Naruishi, Jun-ichi Kido and Hiromichi Yumoto :
カルプロテクチンはマウス骨細胞の炎症および骨代謝関連因子の発現を制御する,
第61回春季日本歯周病学会学術大会, Jun. 2018.
7. Yuka Hiroshima, Takenori Yamamoto and Yasuo Shinohara :
最終糖化産物とPorphyromonas gingivalis由来LPSが誘導するヒト歯肉上皮細胞の遺伝子発現の解析,
第61回春季日本歯周病学会学術大会, Jun. 2018.
8. 大園 瑞音, Takenori Yamamoto, 渡辺 朗, Akiko Yamada, Yuka Hiroshima, Hiroshi Terada and Yasuo Shinohara :
ミトコンドリアカルシウムユニポーター(MCU)の構造と機能の相関解析,
第9回日本生物物理学会中国四国支部大会, May 2017.
9. 谷口 あい, Takenori Yamamoto, 井戸 佑介, Yuka Hiroshima, Akiko Yamada and Yasuo Shinohara :
クロナゼパムがマウスの遺伝子発現に及ぼす影響のマイクロアレイ解析,
日本薬学会年会, Mar. 2017.
10. Takenori Yamamoto, 大園 瑞音, 山越 亮平, Akiko Yamada, Yuka Hiroshima, Hiroshi Terada and Yasuo Shinohara :
酵母発現系によるミトコンドリアカルシウムユニポーター(MCU)の構造機能解析,
日本薬学会年会, Mar. 2017.
11. Takenori Yamamoto, 大園 瑞音, 山越 亮平, Akiko Yamada, Yuka Hiroshima, Hiroshi Terada and Yasuo Shinohara :
酵母再構成系を用いたミトコンドリアカルシウムユニポーターの 構造機能解析,
第38回生体膜と薬物の相互作用シンポジウム, Nov. 2016.
12. 大和 永奈, 山越 亮平, Takenori Yamamoto, Yuka Hiroshima, 三芳 秀人, Mitsuru Shindo, Hiroshi Terada and Yasuo Shinohara :
ミトコンドリアのADP/ATP輸送体はボンクレキン酸とどのように相互作用しているのか,
第55回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会, Nov. 2016.
13. 大園 瑞音, Takenori Yamamoto, 山越 亮平, Akiko Yamada, Yuka Hiroshima, Hiroshi Terada and Yasuo Shinohara :
酵母再構成系を用いたミトコンドリアカルシウムユニポーター(MCU)の構造機能解析,
第55回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会, Nov. 2016.
14. Yuka Hiroshima, Jun-ichi Kido, Eijiro Sakamoto, 阿部 佳織, Kaya Yoshida, Toshihiko Nagata and Yasuo Shinohara :
最終糖化産物はヒト歯肉上皮細胞におけるS100A8およびS100A9発現を上昇する,
第59回秋季日本歯周病学会学術大会, Oct. 2016.
15. Yuka Hiroshima, Jun-ichi Kido, Kaya Yoshida, Kaori Abe, Yasuo Shinohara and Toshihiko Nagata :
Hypoxic condition down-regulates S100A8 expression in human oral epithelial cells,
第59回春季日本歯周病学会学術大会, May 2016.
16. Kaya Yoshida, Natsumi Fujiwara, Yuka Hiroshima, Kaori Abe, Jun-ichi Kido and Kazumi Ozaki :
Porphyhepatic cellsromonas gingivalis inhibits insulin signaling by regulating SOCS3 and IRS-1 in,
第59回春季日本歯周病学会学術大会, May 2016.
17. Yukari Kajiura, Jun-ichi Kido, Yukiko Nakajima, Mika Bandou, Yuji Inagaki, Koji Naruishi, Eijiro Sakamoto, Kaori Abe, Yuka Hiroshima and Toshihiko Nagata :
低酸素環境が誘導するヒト口腔上皮細胞における遺伝子発現の解析,
第58回秋季日本歯周病学会学術大会, Sep. 2015.
18. Yukari Kajiura, Yukiko Bandou, Jun-ichi Kido, Mika Bandou, Yuji Inagaki, Yukiko Nakajima, 生田 貴久, Hiromi Murata, Yuka Hiroshima, Koji Naruishi and Toshihiko Nagata :
歯周病および糖尿病患者の歯肉溝滲出液中のYKL-40レベルの検討,
第57回秋季日本歯周病学会学術大会, Oct. 2014.
19. Mika Bandou, Yuka Hiroshima, Yuji Inagaki, Jun-ichi Kido and Toshihiko Nagata :
ヒト上皮細胞におけるInterleukin-1aによるS100A9遺伝子の転写調節,
第140回日本歯科保存学会春季学術大会, Jun. 2014.
20. Yukari Kajiura, Mika Bandou, Jun-ichi Kido, Yuji Inagaki, 生田 貴久, 橋本 万里, 篠原 宏貴, Masami Ninomiya, Hiromi Murata, Yukiko Nakajima, Satoshi Yoneda, 美原 智恵, Yuka Hiroshima, Keiji Oishi and Toshihiko Nagata :
歯肉溝滲出液中のグリコアルブミンおよびカルプロテクチンを指標とした糖尿病関連歯周炎の診断,
第57回春季日本歯周病学会学術大会, May 2014.
21. Yukari Kajiura, Yukiko Bandou, Jun-ichi Kido, Mika Bandou, Yuji Inagaki, Yukiko Nakajima, 生田 貴久, Hiromi Murata, Yuka Hiroshima, Koji Naruishi and Toshihiko Nagata :
歯周病および糖尿病患者の歯肉溝滲出液中のYKL-40レベルの検討,
第57回日本歯周病学会秋期学術大会抄録集, May 2014.
22. Yukiko Nakajima, Jun-ichi Kido, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Hiromi Murata and Toshihiko Nagata :
低酸素環境がヒト口腔上皮細胞の各種遺伝子発現に及ぼす影響,
第56回秋季日本歯周病学会学術大会, Sep. 2013.
23. Jun-ichi Kido, Mika Bandou, Yukiko Bandou, Yuji Inagaki, Yuka Hiroshima, 梶浦 由加里, Chie Mihara-Wada, Hiromi Murata, 生田 貴久, 篠原 宏貴, Makoto Funaki and Toshihiko Nagata :
糖尿病関連歯周炎の診断マーカーとしての歯肉溝滲出液中グリコアルブミンとカルプロテクチンの有用性,
第56回日本糖尿病学会, May 2013.
24. Jun-ichi Kido, Mika Bandou, Yukiko Bandou, Yuji Inagaki, Yuka Hiroshima, 梶浦 由加里, 美原 智恵, Hiromi Murata, 生田 貴久, 篠原 宏貴, 橋本 万里, Makoto Funaki, Haruhiko Saito and Toshihiko Nagata :
--,
第56回日本糖尿病学会年次学術集会, May 2013.
25. 伊藤 弘, 沼部 幸博, 関野 愉, 村樫 悦子, 井口 一美, 戸円 智幸, 橋本 修一, 佐々木 大輔, 八重柏 隆, 國松 和司, 高井 英樹, 目澤 優, 小方 頼昌, 渡邊 久, 萩原 さつき, 和泉 雄一, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
歯肉溝滲出液(GCF)を用いた歯周病罹患部位の診断と治療効果のモニタリングの有用性 -歯周病迅速診断キット開発に向けて-(第六報),
日本歯科保存学雑誌 第137回秋季学術大会講演抄録集, 65, Nov. 2012.
26. 中島 由紀子, Yuji Inagaki, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
最終糖化産物(AGE)はラット歯髄における石灰化物形成と炎症反応を進展させる,
日本歯科保存学雑誌 第137回秋季学術大会講演抄録集, 97, Nov. 2012.
27. 伊藤 弘, 関野 愉, 村樫 悦子, 井口 一美, 橋本 修一, 沼部 幸博, 佐々木 大輔, 八重柏 隆, 國松 和司, 高井 英樹, 目澤 優, 小方 頼昌, 渡邊 久, 萩原 さつき, 和泉 雄一, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
歯肉溝滲出液(GCF)を用いた歯周病罹患部位の診断と治療効果のモニタリングの有用性-歯周病迅速診断キット開発に向けて-(第五報),
日本歯周病学会会誌 第55回学術大会秋季特別号, Vol.54, 83, Sep. 2012.
28. Jun-ichi Kido, Yuji Inagaki, Mika Bandou, Yukiko Bandou, Yuka Hiroshima, Hiromi Murata, Makoto Funaki, Haruhiko Saito and Toshihiko Nagata :
歯肉溝滲出液中のバイオマーカーを用いた糖尿病関連歯周炎の診断,
第55回日本糖尿病学会年次学術集会 抄録集, 186, May 2012.
29. Yuka Hiroshima, Mika Bandou, Masatoshi Kataoka, Jun-ichi Kido and Toshihiko Nagata :
ヒト口腔上皮細胞のカルプロテクチン発現に及ぼす半夏瀉心湯の影響,
日本歯周病学会会誌 第55回春季学術大会特別号, Vol.54, 131, May 2012.
30. 伊藤 弘, 関野 愉, 村樫 悦子, 井口 一美, 橋本 修一, 沼部 幸博, 佐々木 大輔, 八重柏 隆, 國松 和司, 高井 英樹, 目澤 優, 小方 頼昌, 渡辺 久, 萩原 さつき, 和泉 雄一, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
歯肉溝滲出液(GCF)を用いた歯周病罹患部位の診断と治療効果のモニタリングの有用性 -歯周病迅速診断キット開発に向けて-(第四報),
日本歯周病学会会誌 第55回春季学術大会特別号, Vol.54, 126, May 2012.
31. Kaori Abe, Mika Bandou, Yuka Hiroshima, Jun-ichi Kido and Masatoshi Kataoka :
マイクロチップ基板を用いた血中サイトカインの迅速検出法の構築,
日本歯周病学会会誌 第55回春季学術大会特別号, Vol.54, 114, May 2012.
32. Mika Bandou, Jun-ichi Kido, Yuji Inagaki, Yuka Hiroshima, Hiromi Murata, Takahisa Ikuta, 篠原 宏貴, 橋本 万里, 山田 由加里, Yukiko Bandou, Haruhiko Saito and Toshihiko Nagata :
糖尿病関連歯周炎の診断指標スクリーニングに向けた医科・歯科連携研究,
日本歯周病学会会誌 第55回春季学術大会特別号, Vol.54, 112, May 2012.
33. Jun-ichi Kido, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Hiromi Murata, Chie Mihara-Wada, Masumi Horibe, Satoshi Yoneda, Masami Ninomiya, Keiji Oishi, Eijiro Sakamoto, 中島 由紀子, 生田 貴久, 浅原 洋士 and Toshihiko Nagata :
バイオマーカーを用いた糖尿病関連歯周炎の診断研究,
Journal of the Japanese Association for Dental Science, Vol.31, 86, Mar. 2012.
34. Jun-ichi Kido, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Hiromi Murata, Chie Mihara-Wada, Masumi Horibe, Satoshi Yoneda, Masami Ninomiya, Keiji Oishi, Eijiro Sakamoto, 中島 由紀子, 生田 貴久, 浅原 洋士 and Toshihiko Nagata :
バイオマーカーを用いた糖尿病関連歯周炎の診断研究,
Journal of the Japanese Association for Dental Science, Vol.31, 86, Mar. 2012.
35. Jun-ichi Kido, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Hiromi Murata, Chie Mihara-Wada, Masumi Horibe, Satoshi Yoneda, Masami Ninomiya, Keiji Oishi, 坂本 英次郎, 中島 由紀子, 生田 貴久, 浅原 洋士 and Toshihiko Nagata :
バイオマーカーを用いた糖尿病関連歯周炎の診断研究,
Journal of the Japanese Association for Dental Science, Vol.31, 86, Mar. 2012.
36. Hiromi Murata, Jun-ichi Kido, Mika Bandou, Yuka Hiroshima, Yuji Inagaki and Toshihiko Nagata :
最終糖化産物はマクロファージ様細胞の炎症関連因子の発現を調節する,
日本歯科保存学会雑誌 第135回秋季学術大会プログラム, 200, Oct. 2011.
37. 伊藤 弘, 沼部 幸博, 関野 愉, 村樫 悦子, 井口 一美, 戸円 智幸, 橋本 修一, 佐々木 大輔, 八重柏 隆, 國松 和司, 高井 英樹, 目澤 優, 小方 頼昌, 渡邊 久, 萩原 さつき, 和泉 雄一, Yuka Hiroshima, Jun-ichi Kido and 永田 俊彦 :
歯肉溝滲出液を用いた歯周病罹患部位の診断と治療効果のモニタリングの有用性-歯周病迅速診断キット開発に向けて-第三報,
日本歯科保存学会雑誌 第135回秋季学術大会プロクラム, 124, Oct. 2011.
38. 中島 由紀子, 稲垣 裕司, Mika Bandou, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
最終糖化産物(AGEs)がラット培養歯髄細胞の石灰化物形成と抗菌ペプチド発現に及ぼす影響,
日本歯科保存学会雑誌 第135回秋季学術大会プログラム, 46, Oct. 2011.
39. 伊藤 弘, 沼部 幸博, 関野 愉, 村樫 悦子, 井口 一美, 橋本 修一, 佐々木 大輔, 八重柏 隆, 國松 和司, 高井 英樹, 目澤 優, 小方 頼昌, 渡邊 久, 萩原 さつき, 和泉 雄一, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
歯肉溝滲出液(GCF)を用いた歯周病罹患部位の診断と治療効果のモニタリングの有用性-歯周病迅速診断キット開発に向けて- 第二報,
日本歯周病学会会誌 秋季特別号, Vol.53, 107, Sep. 2011.
40. Yukiko Bandou, Jun-ichi Kido, Yuka Hiroshima, Mika Bandou, Yuji Inagaki, Hiromi Murata, Yosuke Shikama, Makoto Funaki and Toshihiko Nagata :
歯肉溝滲出液中のNKL-40の分析,
日本歯周病学会会誌 秋季特別号, Vol.53, 106, Sep. 2011.
41. Jun-ichi Kido, Kaori Abe, Masatoshi Kataoka, Mika Bandou, Yuka Hiroshima, Yuji Inagaki and Toshihiko Nagata :
マイクロチップELISA法による歯肉溝滲出液中のカルプロテクチン測定,
日本歯周病学会 秋季特別号, Vol.53, 108, Sep. 2011.
42. 中島 由紀子, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
ラット培養歯髄細胞における最終糖化産物(AGEs)の石灰化促進作用,
日本歯科保存学会雑誌 第134回春季学術大会プログラム, 12, Jun. 2011.
43. 美原 智恵, Jun-ichi Kido, Satoshi Yoneda, Yuka Hiroshima, Hiroyuki Seto and Toshihiko Nagata :
上顎 前歯の著しいフレアアウトを伴った薬物性歯肉増殖症の一症例,
日本歯周病学会会誌 春季特別号, Vol.53, 139, May 2011.
44. Mika Bandou, Yuji Inagaki, Jun-ichi Kido, Yuka Hiroshima, Masatoshi Kataoka, Hiromi Murata, Yukiko Bandou, Masami Ninomiya, Eijiro Sakamoto, 中島 由紀子 and Toshihiko Nagata :
歯肉溝滲出液中のグリコアルブミン測定法の確立,
日本歯周病学会会誌 春季特別号, Vol.53, 119, May 2011.
45. 伊藤 弘, 関野 愉, 村樫 悦子, 井口 一美, 沼部 幸博, 橋本 修一, 佐々木 大輔, 八重柏 隆, 國松 和司, 高井 英樹, 目澤 優, 小方 頼昌, 渡邊 久, 萩原 さつき, 和泉 雄一, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
歯肉溝滲出液(GCF)を用いた歯周病罹患部位の診断と治療効果のモニタリングの有用性 -歯周病迅速診断キット開発に向けて- 第1報,
日本歯周病学会会誌 春季特別号, Vol.53, 121, May 2011.
46. Mika Bandou, Yuji Inagaki, Jun-ichi Kido, Yuka Hiroshima, Masatoshi Kataoka, Hiromi Murata, Yukiko Bandou, Masami Ninomiya, 坂本 英次郎, 中島 由紀子 and Toshihiko Nagata :
歯肉溝滲出液中のグリコアルブミン測定法の確立,
日本歯周病学会会誌 春季特別号, Vol.53, 119, May 2011.
47. Yuka Hiroshima, Mika Bandou, Jun-ichi Kido, Masatoshi Kataoka and Toshihiko Nagata :
ヒト口腔上皮細胞におけるカルプロテクチン発現に及ぼす半夏瀉心湯の影響,
日本歯周病学会会誌 春季特別号, Vol.53, 114, May 2011.
48. Chie Mihara-Wada, Jun-ichi Kido, Satoshi Yoneda, Yuka Hiroshima, Hiroyuki Seto and Toshihiko Nagata :
上顎前歯の著しいフレアアウトを伴った薬物性歯肉増殖症患者の一症例,
Journal of the Japanese Association of Periodontology, May 2011.
49. Yukiko Nakajima, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
グルコースが糖尿病ラット由来歯髄細胞の石灰化物形成とオステオポンチン産生に及ぼす影響,
第133回日本歯科保存学会秋季学術大会(岐阜), Oct. 2010.
50. 坂本 英次郎, Chie Mihara-Wada, 徳永 格, 瀬戸 浩行 and Yuka Hiroshima :
ラット実験的歯周炎におけるオステオプロテジェリンの影響,
第53回秋季日本歯周病学会 高松, Sep. 2010.
51. Purevjav Javkhlan, Yuka Hiroshima, Ahmad Azlina, Takahiro Hasegawa, Chenjuan Yao, Tetsuya Akamatsu, Toshihiko Nagata and Kazuo Hosoi :
Calprotectin expression in the mouse salivary gland: Induction by lipopolysaccharide,
第52回歯科基礎医学会(2010年9月20-22日), Sep. 2010.
52. Yuka Hiroshima, Purevjav Javkhlan, Ahmad Azlina, Takahiro Hasegawa, Tetsuya Akamatsu and Kazuo Hosoi :
Porphyromonas gingivalis由来LPSはヒト好中球からのレジスチンの遊離を促進する,
第52回歯科基礎医学会(2010年9月20-22日), Sep. 2010.
53. Takahiro Hasegawa, Ahmad Azlina, Purevjav Javkhlan, Yuka Hiroshima, Chenjuan Yao, Tetsuya Akamatsu and Kazuo Hosoi :
唾液腺細胞におけるアクアポリン5リン酸化のシグナル伝達機構,
第52回歯科基礎医学会(2010年9月20-22日), Sep. 2010.
54. Purevjav Javkhlan, Yuka Hiroshima, Ahmad Azlina, Takahiro Hasegawa, Chenjuan Yao, Tetsuya Akamatsu, Toshihiko Nagata and Kazuo Hosoi :
Calprotectin expression in the mouse salivary gland: Induction by lipopolysaccharide,
Journal of Oral Biosciences, Vol.52, No.supplement, 94, Sep. 2010.
55. Yuka Hiroshima, Javkhlan Purevjav, Ahmad Azlina, Takahiro Hasegawa, Tetsuya Akamatsu and Kazuo Hosoi :
Porphyromonas gingivalis由来LPSはヒト好中球からのレジスチンの遊離を促進する,
Journal of Oral Biosciences, Vol.52, No.supplement, 148, Sep. 2010.
56. Takahiro Hasegawa, Ahmad Azlina, Javkhlan Purevjav, Yuka Hiroshima, Chenjuan Yao, Tetsuya Akamatsu and Kazuo Hosoi :
唾液腺細胞におけるアクアポリン5リン酸化のシグナル伝達機構,
Journal of Oral Biosciences, Vol.52, No.supplement, 164, Sep. 2010.
57. Yuji Inagaki, Jun-ichi Kido, Mika Bandou, Yuka Hiroshima and Chie Mihara-Wada :
糖尿病関連歯周炎における歯肉溝浸出液中のバイオマーカーの分析,
第53回 日本糖尿病学会, May 2010.
58. Yuka Hiroshima, Mika Bandou, Jun-ichi Kido, Eijiro Sakamoto, 中島 由紀子, Masatoshi Kataoka and Toshihiko Nagata :
Porphyromonas gingivalis由来LPSはヒト好中球からのレジスチンの遊離を促進する,
第53回春季日本歯周病学会学術大会, Vol.52, 105, May 2010.
59. Yuka Hiroshima, Mika Bandou, Jun-ichi Kido, 坂本 英次郎, 中島 由紀子, Masatoshi Kataoka and Toshihiko Nagata :
Porphyromonas gingivalis由来LPSはヒト好中球からのレジスチンの遊離を促進する,
第53回春季日本歯周病学会学術大会, Vol.52, 105, May 2010.
60. Jun-ichi Kido, Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Masatoshi Kataoka, Chie Mihara-Wada, Masumi Horibe, Satoshi Yoneda, 坂本 英次郎, 中島 由紀子, Masami Ninomiya, Keiji Oishi, 淺原 洋士 and Toshihiko Nagata :
歯肉溝浸出液中の糖尿病関連歯周炎バイオマーカーの検索,
Journal of the Japanese Association of Periodontology, Vol.52, 97, May 2010.
61. Yuji Inagaki, Jun-ichi Kido, Mika Bandou, Yuka Hiroshima, Masatoshi Kataoka, Chie Mihara-Wada, Masumi Horibe, Satoshi Yoneda, 坂本 英次郎, 中島 由紀子, Masami Ninomiya, Keiji Oishi, 淺原 洋士 and Toshihiko Nagata :
糖尿病関連歯周炎における歯肉溝滲出液中のバイオマーカーの分析,
Journal of the The Japan Diabetes Society, Vol.53, No.Suppl.1, S-145, Apr. 2010.
62. Yuka Hiroshima, Mika Bandou, Jun-ichi Kido, Yuji Inagaki, Chie Mihara-Wada, Keiji Oishi, Masatoshi Kataoka and Toshihiko Nagata :
ヒト口腔上皮細胞における抗菌ペプチド遺伝子発現に及ぼす小柴胡湯の影響,
第131回日本歯科保存学会秋季学術大会, Oct. 2009.
63. Yuji Inagaki, Mika Bandou, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
オスモティックストレスが歯髄細胞の硬組織形成能とオステオポンチン産生に及ぼす影響,
第131回日本歯科保存学会秋季学術大会, Oct. 2009.
64. Keiji Oishi, Yuka Hiroshima and Toshihiko Nagata :
著明な歯肉増殖を伴う慢性歯周炎患者の一症例,
Journal of the Japanese Association of Periodontology, Vol.51, 106, Oct. 2009.
65. Chie Mihara-Wada, 徳永 格, 瀬戸 浩行, 大場 博史, Yuka Hiroshima, Jun-ichi Kido and Toshihiko Nagata :
ラット実験的歯周炎におけるオステオプロテジェリンの骨吸収と炎症におよぼす効果,
第52回秋季日本歯周病学会学術大会, Vol.51, 93, Oct. 2009.
66. Mika Bandou, Yuka Hiroshima, Yuji Inagaki, Masatoshi Kataoka, Chie Mihara-Wada, Masumi Horibe, Satoshi Yoneda, Keiji Oishi, Masami Ninomiya, Javkhlan Purevjav, Jun-ichi Kido and Toshihiko Nagata :
糖尿病関連歯周炎における歯肉溝浸出液中バイオマーカーの分析,
Journal of the Japanese Association of Periodontology, Vol.51, 101, Oct. 2009.
67. Yuka Hiroshima, Mika Bandou, Jun-ichi Kido, Masatoshi Kataoka and Toshihiko Nagata :
ヒト歯肉上皮細胞における抗菌ペプチド遺伝子発現のマイクロアレイ法による解析,
第52回秋季日本歯周病学会学術大会, Vol.51, 90, Oct. 2009.
68. Jun-ichi Kido, Masatoshi Kataoka, 日野 真美, Mika Bandou, Yuka Hiroshima and Toshihiko Nagata :
歯周病バイオマーカーのマイクロチップ基板を用いた測定と歯周病診断への応用,
第2回日本口腔検査学会, 28, Oct. 2009.
69. Jun-ichi Kido, Masatoshi Kataoka, Mika Bandou, Yuka Hiroshima, Chie Mihara-Wada and Toshihiko Nagata :
マイクロチップ基板を用いたカルプロテクチンの測定‐歯周病診断法への応用の可能性について‐,
第52回春季日本歯周病学会学術大会, Vol.51, 114, May 2009.

Et cetera, Workshop:

1. 鹿庭 美奈子, 喜田 悠太, Keiji Murakami, Yuka Hiroshima, Takashi Amoh and Hideki Fujii :
BNCのインフルエンザ感受性細胞への接着に関与する温度条件,
四国歯学会第54回例会, Mar. 2019.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 糖尿病病態の歯周組織におけるS100A8の役割と作用機構の解明 (Project/Area Number: 17K17352 )
  • 人工細胞を用いたオーラルケアシステムの基礎研究 (Project/Area Number: 17H04418 )
  • Investigation of molecular mechanism of S100A8 in diabetes-associated periodontitis (Project/Area Number: 15H06451 )
  • レジスチンは唾液腺炎症のモジュレーターとなるか (Project/Area Number: 23792125 )
  • Search by Researcher Number (60545143)