Tokushima University / Educator and Researcher Directory --- Yamaguchi, Tetsuo

Personal Web Page

Field of Study

○	Orthopaedics, Sports Medicine, Molecular Biology

Subject of Study

○	臨床研究(スポーツ傷害とその予防, 運動器エコー), 基礎研究(運動習慣による骨格筋の遺伝子変化, 肩関節拘縮の分子機構)

Book / Paper

Book:

1.	Shihori Tanabe and Tetsuo Yamaguchi : PPARs and Their Roles in the Molecular Network and Disease, Nova Science Publishers, Inc., New York, 2013.
2.	Tetsuo Yamaguchi, Shihori Tanabe and Naoshi Fukui : Review; Mild heat stress changes cell differentiation and function., Research Signpost, 2012.

Academic Paper (Judged Full Paper):

1.	Hiroaki Nishimoto, Shoji Fukuta, Naoshi Fukui, Koichi Sairyo and Tetsuo Yamaguchi : Characteristics of gene expression in frozen shoulder, BMC Musculoskeletal Disorders, Vol.23, No.1, 811, 2022. (Summary) Severe frozen shoulder (FS) is often resistant to treatment and can thus result in long-term functional impairment. However, its etiology remains unknown. We hypothesized that gene expression of FS would vary by synovial location. The synovial tissues of patients with FS were collected prospectively and analyzed for the expression of 19 genes. Synovial tissues from patients with rotator cuff tear (RCT) or shoulder instability (SI) were also analyzed as controls. A total of 10 samples were analyzed from each group. The specimens were arthroscopically taken from three different locations: rotator interval (RI), axillary recess (AX), and subacromial bursa (SAB). Total RNA was extracted from the collected tissues and was analyzed by real-time polymerase chain reaction for the following genes: matrix metalloproteinases (MMPs); tissue inhibitors of metalloproteinases (TIMPs); inflammatory cytokines (IL1B, TNF, and IL6); type I and II procollagen (COL1A1 and COL2A1); growth factors (IGF1 and TGFB1); neural factors (NGF and NGFR); SOX9; and ACTA2. Site-specific analysis showed that MMP13, IL-6, SOX9, and COL1A1 were increased in all three sites. Four genes (MMP3, MMP9, COL2A1, and NGFR) were increased in the AX, MMP3 in the RI, and NGFR in the SAB were increased in the FS group than in the RCT and SI groups. In the FS group, there was a correlation between the expression of genes related to chondrogenesis (MMP2, IGF1, SOX9, COL2A1, NGF, and NGFR) or fibrosis (MMP9, TGFB1, and COL1A1). The expression levels of numerous MMPs, pro-inflammatory cytokines, and collagen-related genes were increased in the FS group, suggesting that catabolic and anabolic changes have simultaneously occurred. In addition, genes related to chondrogenesis or fibrosis were highly expressed in the FS group, which might have affected the range of motion limitation of the shoulder. Compared to RI and SAB, the AX was the most common site of increased expression in FS. Analyzing the lower region of the shoulder joint may lead to the elucidation of the pathogenesis of FS. (Keyword) frozen shoulder / gene expression / fibrosis / chondrogenesis (Tokushima University Institutional Repository) ● Metadata: 117803 (Link to Publication Site) ● Publication site (DOI): 10.1186/s12891-022-05762-3 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36008780 ● Search Scopus @ Elsevier (PMID): 36008780 ● Search Scopus @ Elsevier (DOI): 10.1186/s12891-022-05762-3 (Tokushima University Institutional Repository: 117803, DOI: 10.1186/s12891-022-05762-3, PubMed: 36008780)
2.	Hiroaki Nishimoto, Hikari Kino, 藤原夕菜 and Tetsuo Yamaguchi : 大学生における遺伝子教育の効果, Journal of Science Education in Japan, Vol.45, No.1, 49-56, 2021. (Keyword) Genetic education / Molecular biology / Experiment / Hmanities and Science / University students (Link to Publication Site) ● Publication site (DOI): 10.14935/jssej.45.49 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390569070681367552 ● Search Scopus @ Elsevier (DOI): 10.14935/jssej.45.49 (DOI: 10.14935/jssej.45.49, CiNii: 1390569070681367552)
3.	西本浩章 and Tetsuo Yamaguchi : Knee Pain Experienced by Amateur Cyclists and Factors Affecting It, Japanese Journal of Clinical Sports Medicine, Vol.28, No.2, 389-395, 2020. (Keyword) amateur cyclists / knee pain / quadriceps / アマチュアサイクリスト / 膝痛 / 大腿四頭筋 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520853833805377536 (CiNii: 1520853833805377536)
4.	川道幸司, Naoto Suzue and Tetsuo Yamaguchi : Muscle thickness and echo-intensity in the vastus intermedius after anterior cruciate ligament injury, Japanese Journal of Clinical Sports Medicine, Vol.28, No.1, 25-31, 2020.
5.	HIroaki Nishimoto and Tetsuo Yamaguchi : Survey on Athletic Performance after lower limbs stress fracture among mid- and long-distance athletes, Japanese Journal of Clinical Sports Medicine, Vol.28, No.1, 160-165, 2020.
6.	川道幸司, Tetsuo Yamaguchi, 宮脇鈴子, 岡本和久, 植村直子 and Shinjiro Takata : Characteristics of muscle stiffness in the lower limb skeletal muscles of healthy individuals Analysis of muscle stiffness with the application of ultrasound elastography, The Japanese Journal of Rehabilitation Medicine, Vol.54, No.10, 800-807, 2017. (Summary) <p>Objective:To investigate the lower limb skeletal muscle stiffness in healthy individuals.</p><p>Methods:Using ultrasonographic elastography, we measured the degree of stiffness of the rectus femoris and medial head of the gastrocnemius in healthy individuals and investigated the relationships between muscle stiffness and thickness, a quantitative measure of muscles, and between muscle stiffness and brightness, a qualitative measure of muscles. Furthermore, relationships between muscle stiffness and age, body weight, and body mass index (BMI) were also studied.</p><p>Results:Rectus femoris stiffness was positively correlated with muscle thickness. Rectus femoris stiffness had a weak negative correlation with muscle brightness and a weak positive correlation with body weight and BMI. Stiffness of the medial head of the gastrocnemius showed no correlation with any of the study variables. Muscle stiffness did not correlate with age in either of the muscles. No sex-related difference was found in the degree of muscle stiffness.</p><p>Conclusion:Although rectus femoris stiffness was associated with muscle thickness and brightness, these relationships were not observed for muscle stiffness of the medial head of the gastrocnemius. The data suggested that rectus femoris stiffness reflects the quantitative and qualitative states of the muscle, and the presence of such relationships may depend on the location of the muscle.</p> (Keyword) skeletal muscle / muscle stiffness / ultrasonographic elastography (Link to Publication Site) ● Publication site (DOI): 10.2490/jjrmc.54.800 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282680250960512 ● Search Scopus @ Elsevier (DOI): 10.2490/jjrmc.54.800 (DOI: 10.2490/jjrmc.54.800, CiNii: 1390282680250960512)
7.	Toru Adachi, Shigeru Obara and Tetsuo Yamaguchi : 持久性運動後の血糖変動から糖尿病リスクを検出できるか?, Journal of Running Science, Vol.29, No.1, 1-15, 2017. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520853832058972032 (CiNii: 1520853832058972032)
8.	Tetsuo Yamaguchi : 【筋から始まるからだの適応】骨格筋再生を加速させる温熱負荷法の可能性, Journal of Health, Physical Education and Recreation, Vol.64, No.2, 101-105, 2014. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520290882757445632 (CiNii: 1520290882757445632)
9.	Tetsuo Yamaguchi and 福井尚志 : Effects of continuous mild changes in temperature on myogenesis in human skeletal myoblasts, The Journal of the Japanese Orthopaedic Association, Vol.88, No.1, 16-22, 2014. (Keyword) Mild heat stress / Skeletal myoblasts / Fiber type / Mitochondria (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520853834786743424 (CiNii: 1520853834786743424)
10.	Nobuho Tanaka, Yasuko Ikeda, Tetsuo Yamaguchi, Hiroshi Furukawa, Hiroyuki Mitomi, Takumi Nakagawa, Shigeto Tohma and Naoshi Fukui : α5β1 integrin induces the expression of noncartilaginous procollagen gene expression in articular chondrocytes cultured in monolayers., Arthritis Research & Therapy, Vol.15, No.5, R127, 2013. (Summary) The result of this study has shown, for the first time, that 51 integrin may be responsible for the induction of non-cartilaginous collagen expression in chondrocytes undergoing dedifferentiation. Again, this study has shown that the inhibition of ligand ligation to integrins may be an effective strategy to inhibit phenotypic change of cultured chondrocytes, and to improve the quality of matrix synthesized by primary cultured chondrocytes. (Link to Publication Site) ● Publication site (DOI): 10.1186/ar4307 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24286194 ● Search Scopus @ Elsevier (PMID): 24286194 ● Search Scopus @ Elsevier (DOI): 10.1186/ar4307 (DOI: 10.1186/ar4307, PubMed: 24286194)
11.	Tetsuo Yamaguchi, Maiko Omori, Nobuho Tanaka and Naoshi Fukui : Distinct and additive effects of sodium bicarbonate and continuous mild heat stress on fiber type shift via calcineurin/NFAT pathway in human skeletal myoblasts., American Journal of Physiology, Cell Physiology, Vol.305, No.3, C323-33, 2013. (Summary) Ingestion of sodium bicarbonate (NaHCO3) is known to enhance athletic performance, probably via increased extracellular buffering capacity. At present, little is known about the direct effects of NaHCO3 on myogenesis, especially in vitro. Here, we examined the effects of NaHCO3 and the combined effects of NaHCO3 and continuous mild heat stress (CMHS) at 39°C on the differentiation of human skeletal muscle myoblasts (HSMMs). Levels of myosin heavy chain (MyHC) type I mRNA increased with increasing NaHCO3 concentrations; in contrast, those of MyHC IIx decreased. The NaHCO3-induced fast-to-slow shift was additively enhanced by CMHS. Likewise, intracellular calcium levels and expression of three factors, nuclear factor of activated T cells c2 (NFATc2), NFATc4, and peroxisome-proliferator-activated receptor-γ coactivator-1α, were upregulated with increasing NaHCO3 concentrations; moreover, these effects of NaHCO3 were additively enhanced by CMHS. Overexpression experiments and small interfering RNA-mediated knockdown experiments confirmed that NFATc2 and NFATc4 were involved in MyHC I regulation. The present study provided evidence that NaHCO3 and CMHS distinctly and additively induced a fast-to-slow fiber type shift through changes in intracellular calcium levels and the modulation of calcium signaling. (Link to Publication Site) ● Publication site (DOI): 10.1152/ajpcell.00393.2012 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23703530 ● Search Scopus @ Elsevier (PMID): 23703530 ● Search Scopus @ Elsevier (DOI): 10.1152/ajpcell.00393.2012 (DOI: 10.1152/ajpcell.00393.2012, PubMed: 23703530)
12.	Naoshi Fukui, Yasuko Ikeda, Nobuho Tanaka, Masahiro Wake, Tetsuo Yamaguchi, Hiroyuki Mitomi, Satoru Ishida, Hiroshi Furukawa, Yoshiki Hamada, Yoshinari Miyamoto, Motoji Sawabe, Toshiyuki Tashiro, Yozo Katsuragawa and Shigeto Tohma : αvβ5 integrin promotes dedifferentiation of monolayer-cultured articular chondrocytes., Arthritis and Rheumatism, Vol.63, No.7, 1938-1949, 2011. (Summary) When cultured in monolayers, articular chondrocytes undergo an obvious phenotypic change. Although the involvement of integrins has been suggested, the exact mechanisms of the change have not been determined. This study was undertaken to clarify the mechanisms underlying the loss of chondrocyte phenotype early after plating. Primary cultured human articular chondrocytes were used for the experiments. Involvement of respective integrins in the phenotypic change was investigated in RNA interference (RNAi) experiments. A signaling pathway involved in the change was identified in experiments using specific inhibitors and adenoviruses encoding mutated genes involved in the pathway. Adenoviruses carrying mutated GTPases were used to determine the involvement of small GTPases in the process. In monolayer-cultured chondrocytes, suppression of αv or β5 integrin expression by RNAi inhibited morphologic changes in the cells and increased (or prevented a reduction in) the expression of various cartilage matrix genes. Consistent results were obtained in experiments using a blocking antibody and a synthetic inhibitor of αvβ5 integrin. The decrease in cartilage matrix gene expression in chondrocytes after plating was mediated by ERK signaling, which was promoted primarily by αvβ5 integrin. In articular chondrocytes, the affinity of αvβ5 integrin for ligands was regulated by the small GTPase R-Ras. R-Ras was gradually activated in monolayer-cultured chondrocytes after plating, which caused a gradual decline in cartilage matrix gene expression through enhanced αvβ5 integrin activation and the subsequent increase in ERK signaling. Our findings indicate that αvβ5 integrin may be involved in the change that occurs in monolayer-cultured chondrocytes after plating. (Keyword) analysis of variance / Blotting, Western / Cartilage, Articular / Cell Dedifferentiation / Cells, Cultured / Chondrocytes / Humans / immunohistochemistry / RNA Interference / Receptors, Vitronectin (Link to Publication Site) ● Publication site (DOI): 10.1002/art.30351 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21425129 ● Search Scopus @ Elsevier (PMID): 21425129 ● Search Scopus @ Elsevier (DOI): 10.1002/art.30351 (DOI: 10.1002/art.30351, PubMed: 21425129)
13.	Tetsuo Yamaguchi, Takayoshi Suzuki, Hideaki Arai, Shihori Tanabe and Yoriko Atomi : Continuous mild heat stress induces differentiation of mammalian myoblasts, shifting fiber type from fast to slow., American Journal of Physiology, Cell Physiology, Vol.298, No.1, C140-8, 2009. (Summary) Local hyperthermia has been widely used as physical therapy for a number of diseases such as inflammatory osteoarticular disorders, tendinitis, and muscle injury. Local hyperthermia is clinically applied to improve blood and lymphatic flow to decrease swelling of tissues (e.g., skeletal muscle). As for muscle repair following injury, the mechanisms underlying the beneficial effects of hyperthermia-induced muscle repair are unknown. In this study, we investigated the direct effects of continuous heat stress on the differentiation of cultured mammalian myoblasts. Compared with control cultures grown at 37 degrees C, incubation at 39 degrees C (continuous mild heat stress; CMHS) enhanced myotube diameter, whereas myotubes were poorly formed at 41 degrees C by primary human skeletal muscle culture cells, human skeletal muscle myoblasts (HSMMs), and C2C12 mouse myoblasts. In HSMMs and C2C12 cells exposed to CMHS, mRNA and protein levels of myosin heavy chain (MyHC) type I were increased compared with the control cultures. The mRNA level of MyHC IIx was unaltered in HSMMs and decreased in C2C12 cells, compared with cells that were not exposed to heat stress. These results indicated a fast-to-slow fiber-type shift in myoblasts. We also examined upstream signals that might be responsible for the fast-to-slow shift of fiber types. CMHS enhanced the mRNA and protein levels of peroxisome proliferator-activated receptor-gamma coactivator (PGC)-1alpha in HSMMS and C2C12 cells but not the activities of MAPKs (ERK1/2 and p38 MAPK) in HSMMs and C2C12 cells. These data suggest that CMHS induces a fast-to-slow fiber-type shift of mammalian myoblasts through PGC-1alpha. (Keyword) Actins / Animals / cell differentiation / Cells, Cultured / Genes, Reporter / Green Fluorescent Proteins / Heat-Shock Proteins / Hot Temperature / Humans / Mammals / Mice / Mitogen-Activated Protein Kinase 3 / Muscle Fibers, Fast-Twitch / Muscle Fibers, Skeletal / Muscle Fibers, Slow-Twitch / Myoblasts / Myosin Heavy Chains / Protein Isoforms / RNA, Messenger / Reverse Transcriptase Polymerase Chain Reaction / Transcription Factors / p38 Mitogen-Activated Protein Kinases (Link to Publication Site) ● Publication site (DOI): 10.1152/ajpcell.00050.2009 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19605738 ● Search Scopus @ Elsevier (PMID): 19605738 ● Search Scopus @ Elsevier (DOI): 10.1152/ajpcell.00050.2009 (DOI: 10.1152/ajpcell.00050.2009, PubMed: 19605738)
14.	Tetsuo Yamaguchi, Hideaki Arai, Naoki Katayama, Tomoji Ishikawa, Kiyoshi Kikumoto and Yoriko Atomi : Age-related increase of insoluble, phosphorylated small heat shock proteins in human skeletal muscle., The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, Vol.62, No.5, 481-489, 2007. (Summary) Among mammalian heat shock proteins (Hsps), small Hsps (sHsps) are constitutively expressed in skeletal muscles. We investigated age-related changes of phosphorylation and cellular distribution of representative sHsps (Hsp27 and alphaB-crystallin) in human vastus lateralis muscle under resting conditions. We also examined upstream kinases which may be responsible for phosphorylation of sHsps, namely p38 mitogen-activated protein kinase (MAPK), MAPK-activated protein kinase-2, and extracellular signal-regulated kinase-1/2. The study groups consisted of nine young (15-38 years old) and nine aged (51-79 years old) patients who underwent orthopedic surgery. sHsps protein levels were higher in the insoluble fraction of aged muscles. The phosphorylated states of sHsps were enhanced in both the soluble and insoluble fraction of aged patients. The phosphorylated form of each upstream kinase was elevated in aged patients. Ubiquitinated proteins accumulated in the insoluble fractions of aged muscles. Aging mechanisms may affect the activation process of MAPKs, and the phosphorylation and accumulation of sHsps. (Keyword) Adolescent / Aged / Aging / Blotting, Western / Electrophoresis, Polyacrylamide Gel / Heat-Shock Proteins, Small / Humans / Middle Aged / Mitogen-Activated Protein Kinases / Muscle, Skeletal / Reverse Transcriptase Polymerase Chain Reaction / Signal Transduction (Link to Publication Site) ● Publication site (DOI): 10.1093/gerona/62.5.481 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 17522351 ● Search Scopus @ Elsevier (PMID): 17522351 ● Search Scopus @ Elsevier (DOI): 10.1093/gerona/62.5.481 (DOI: 10.1093/gerona/62.5.481, PubMed: 17522351)
15.	Tadatsugu MORIMOTO, Mitsuhiro SUMI, Katsuya FUJIMOTO, Manabu KUSHIDA, Shuya IDE, Tetsuo Yamaguchi and Satoru MOTOKAWA : A Case of Femoral Neck Fracture Due to Amyloid Bone Cyst of a Patient Undergoing Long-Term Hemodialysis, Orthopedics & Traumatology, Vol.50, No.1, 245-248, 2001. (Summary) We report a case of femoral neck pathological fracture due to amyloid bone cyst. The patient was a 45-year-old female who had been undergoing hemodialysis for 24 years, who developed large amyloid bone cysts of the femoral neck and acetabulum. She visited our hospital after experiencing hip pain while riding a bus.She was diagnosed with a femoral neck pathological fracture and treated with non-cemented prosthetic replacement of the femoral neck, curettage and bone grafting of the acetabulum cyst. Pathological study of the tissue revealed amyloid deposits. Diagnosis of femoral neck fractures due to amyolid bone cyst, should be considered when examining patients under going long-term hemodyalisis with hip pain. (Link to Publication Site) ● Publication site (DOI): 10.5035/nishiseisai.50.245 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679909902976 ● Search Scopus @ Elsevier (DOI): 10.5035/nishiseisai.50.245 (DOI: 10.5035/nishiseisai.50.245, CiNii: 1390282679909902976)
16.	三浦真弘, 加藤征治, Tetsuo Yamaguchi and 麻生邦一 : 後外側構成体における膝窩筋の運動学的意義について解剖学的検索, 九州·山口スポーツ医·科研究会誌, Vol.13, 10-16, 2001. (Keyword) 解剖学
17.	森本忠嗣, 角光宏, 櫛田学, 井手衆哉, Tetsuo Yamaguchi and 本川哲 : 全身性エリテマトーデスに合併したKienboeck病の1例, Orthopeadics and Traumatology, Vol.44, No.2, 197-201, 2001. (Keyword) 月状骨
18.	森本忠嗣, 角光宏, 櫛田学, 井手衆哉, Tetsuo Yamaguchi and 本川哲 : Kienboeck病に合併した手根管症候群の1例, Clinical Orthopaedic Surgery, Vol.36, No.2, 229-232, 2001. (Keyword) shoulder joint range of motion
19.	Tetsuo Yamaguchi, Yoshihisa Yamaguchi, Masayuki Yamada, Satoru Motokawa, Mitsuhiro Sumi and Hiroyuki Shindo : The Relationship Between the Range of Motion in the Ankle and Body Mass Index, Japanese Journal of Orthopaedic Sports Medicine, Vol.19, No.4, 49-52, 1999. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1573668924459779712 (CiNii: 1573668924459779712)
20.	Tetsuo Yamaguchi, Toru Hirano, Kenji Kumagai, Toshiyuki Tsurumoto, Hiroyuki Shindo, Ryuzo Majima and Nobuyuki Arima : Osteitis fibrosa cystica generalizata with adult T-cell leukaemia: a case report., British Journal of Haematology, Vol.107, No.4, 892-894, 1999. (Summary) We report on a 62-year-old female initially suffering from extreme pain in both her lower extremities. Plain radiographs revealed multiple osteolytic lesions. Laboratory analyses indicated high levels of serum calcium and parathyroid hormone related protein (PTHrP) and detected HTLV-1 antibody. Histological examination of biopsied specimens which were obtained from osteolytic lesions indicated osteitis fibrosa cystica (OFC) without tumour cells. After the initial biopsy, a subcutaneous mass developed in the left thigh. Microsections of the biopsied mass disclosed adult T-cell leukaemia (ATL) neoplastic cells. Immunohistochemical findings revealed that PTHrP secreted from ATL neoplastic cells induced the OFC. (Keyword) Female / Femoral Fractures / Fractures, Spontaneous / Humans / Leukemia-Lymphoma, Adult T-Cell / Middle Aged / Osteitis Fibrosa Cystica (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 10606900 ● Search Scopus @ Elsevier (PMID): 10606900 (PubMed: 10606900)
21.	Tetsuo Yamaguchi, Syuya IDE, Manabu KUSHIDA, Kazushige MAEDA, Mitsuhiro SUMI and Satoru MOTOKAWA : Results of Cementless Total Hip Arthroplasty using Osteonics Prosthesis, Orthopedics & Traumatology, Vol.48, No.3, 857-862, 1999. (Summary) We present the results of 42 total hip arthroplasties using Osteonics femoral components with a mean follow-up period of 25 months (range, 12 to 60 months). Femoral components with arc deposition (AD) have been evaluated in 14 patients, while those with hydroxyapatite (HA) coating in 28 patients. The clinical results of both femoral components were excellent. The average Japan Orthopaedic Association hip score increased from 44 prior to the operation to 90 at the time of the last follow-up. All radiographs of both groups were measured to examine the presence of reactive line, cancellous condensation and subsidence. The reactive line occurred in 2 hips (14%) of the AD group at zones I and VII which contain a porous coating of the stem, but none in the HA group after 1 to 2 years. Cancellous condensation occurred in the HA group, more than the AD group, significantly at zone II. Our radiological results show that the HA coating can provide durable implant fixation. (Link to Publication Site) ● Publication site (DOI): 10.5035/nishiseisai.48.857 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679910150400 ● Search Scopus @ Elsevier (DOI): 10.5035/nishiseisai.48.857 (DOI: 10.5035/nishiseisai.48.857, CiNii: 1390282679910150400)
22.	Kazushige MAEDA, Mitsuhiro SUMI, Manabu KUSHIDA, Syuya IDE, Tetsuo Yamaguchi and Satoru MOTOKAWA : Clinical Results of Implant Arthroplasty for Avascular Necrosis of Femoral Head, Orthopedics & Traumatology, Vol.48, No.4, 1173-1176, 1999. (Summary) We investigated the operative results of 26 patients (34 hips) treated by hemiarthroplasty (Prosthesis)or total hip arthroplasty (THA) for avascular necrosis of the femoral head (ANF) classified according to the etiology.Clinical results using JOA hip score averaged 79.7 points in prosthesis and 91.2 points in THA after surgery. There was no correlation between them.On X-ray findings, the rate of loosening was shown for 23.1% of prosthesisind-ucedusing of steroid and 30.0% of prosthesis induced alcohol drinking. There was no loosening in THA.It is important to prevent loosening in prosthesis in ANF induced-steroid and induced-drinking. (Link to Publication Site) ● Publication site (DOI): 10.5035/nishiseisai.48.1173 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204934365056 ● Search Scopus @ Elsevier (DOI): 10.5035/nishiseisai.48.1173 (DOI: 10.5035/nishiseisai.48.1173, CiNii: 1390001204934365056)
23.	Shuya IDE, Mitsuhiro SUMI, Kazushige MAEDA, Manabu KUSHIDA, Tetsuo Yamaguchi, Satoru MOTOKAWA and Hiroshi MAEDA : Operative Treament of Hip Disease in Patients with Renal Failure, Orthopedics & Traumatology, Vol.48, No.1, 173-176, 1999. (Summary) We experienced 10 cases with hip disease for renal failure for 5 years. 10 patients with an average age of 54.3 years underwent operative treatment. They consisted of 3 hip fractures, 2 avascular necrosis of the femoral head, 2 coxarthrosis' and 3 ectopic calcification of the hip joint. The average hemodialysis period was 9.3 years, and the average follow-up period was 2.9 years.1 femoral neck fracture case showed nonunion after fixation with screws, for which we performed cemented bipolar hemiart-hroplasty. Revision was however required due to osteolysis around the prosthesis. Because the ratio of loosening due to hemodialys is still high, further tmprorement of the operation is neccessary. (Link to Publication Site) ● Publication site (DOI): 10.5035/nishiseisai.48.173 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679911468672 ● Search Scopus @ Elsevier (DOI): 10.5035/nishiseisai.48.173 (DOI: 10.5035/nishiseisai.48.173, CiNii: 1390282679911468672)
24.	本川哲, 角光宏, 前田和成, 櫛田学, 井手衆哉 and Tetsuo Yamaguchi : 外傷性股関節後方脱臼に合併した骨頭骨折の治療成績, 整形外科・災害外科, Vol.42, No.3, 263-269, 1999.
25.	太田美穂, 武藤芳照, 高杉紳一郎, 安田幸一郎, 田島宝, 鈴木紅, 牧山尚也 and Tetsuo Yamaguchi : 中高年者への水中運動・水泳に伴う障害の予防対策の検討, 水と健康医学研究会誌, Vol.1, No.1, 33-40, 1998.
26.	Tetsuo Yamaguchi, 山口善久 and 山田正幸 : ソフトボールピッチャーに生じた尺骨茎状突起骨折, 九州スポーツ医科学会誌, Vol.10, 61, 1998.
27.	Tetsuo Yamaguchi, Ryuzo MAJIMA, Toshiyuki TSURUMOTO, Yoko NARABAYASHI, Satoshi IWANAGA, Nobuyuki ARIMA and Toru HIRANO : A Case of Adult T-cell Leukemia with a Pathological Fracture, Orthopedics & Traumatology, Vol.46, No.4, 1134-1139, 1997. (Summary) A 62 year-woman was admitted with pain in the chest, lower back and both lower extremities in January 1995. Clinical findings revealed osteolytic lesions and hypercalcemia. She sustained a subtrochanteric fracture of the left femur after a fall. We treated the fracture with an intramedullary nail. Biopsy of the osteolytic lesions around the fracture demonstrated osteitis fibrosa cystica with no surrounding tumor cells. After the operation, we demonstrated positive HTLV-1 antisera and a high level of CD4, CD4/CD8 and CD25. In June, a subcutaneous tumor appeared in the left thigh. The biopsy demonstrated a T-cell lymphoma, and we confirmed a diagnosis of ATL. Serum PTHrP was high and serum intact PTH low, suggesting that the cause of the osteolytic lesions was PTHrP originating from the ATL tumor cells. (Link to Publication Site) ● Publication site (DOI): 10.5035/nishiseisai.46.1134 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679911096832 ● Search Scopus @ Elsevier (DOI): 10.5035/nishiseisai.46.1134 (DOI: 10.5035/nishiseisai.46.1134, CiNii: 1390282679911096832)
28.	Tetsuo Yamaguchi, Nobuyuki ITOU, Masao ETOU, Tadashi TOMONAGA, Shin'ichi HARADA, Satoshi NAKAMURA and Katsuro IWASAKI : Loose Bodies in the Bursa around the Shoulder Joint:A report of two cases, Orthopedics & Traumatology, Vol.46, No.1, 19-23, 1997. (Summary) The shoulder joint is a relatively rare site for loose bodies of the synovium. In this study we present two cases with loose bodies in the bursa around the shoulder joint.Case 1: A 42-year-old male who had swelling and discomfort with limitation of motion of the right shoulder. Roentgenogram and CT scan showed destruction of the acromion and retention of fluid on the subacrominal brrsa. Operative findings revealed numerous loose bodies. A definite diagnosis of tuberculous bursitis was revealed by histological examination due to the presence of granulation and caseous necrosis.Case 2: An 88-year-old female had been suffering from right shoulder pain for 7 years. Roentgenogram showed numerous radiodense bodies in the right shoulder joint. CT scan and MRI also revealed the same findings. Numerous loose bodies removed from the shoulder were found to be a combination of cartilage and bony tissue. Histologically, this case was diagnosed as synovial osteochondromatosis.In both cases, the lesion was treated by removal of the loose bodies and a partial synovectomy with satisfactory results. From this study, it can be concluded that in cases with loose bodies around the joints, the final diagnosis can be made after histological examination. (Link to Publication Site) ● Publication site (DOI): 10.5035/nishiseisai.46.19 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204935724544 ● Search Scopus @ Elsevier (DOI): 10.5035/nishiseisai.46.19 (DOI: 10.5035/nishiseisai.46.19, CiNii: 1390001204935724544)
29.	Takeshi Miyaji, Katsuro Takahashi, Junji Oda, Katsuki Taguchi, Ritsu Tsujimoto, Tetsuo Yamaguchi and Katsuro Iwasaki : Clinical Experience of Two Cases of Synovial Osteochondromatosis of the Hip., Orthopedics & Traumatology, Vol.45, No.3, 739-742, 1996. (Summary) We experienced two cases of synovial osteochondromatosis of the hip.Case 1, a 12-year old boy complained of limitation in his right hip motion. Roentgenograms showed many small calcified or ossified particles in the right hip joint. We performed synovectomy, and found the hip joint to be filled with more than two hundred calcified loose bodies. Range of motion of the hip recovered after surgery. Microscopic examination, revealed the synovium to have an osseous and cartilaginous lesion.Case 2, a 24-year-old man complained of right coxalgia and limitation of right hip motion since he was 20 years old. Roentgenograms showed right hip joint space narrowing and osteoporosis. Hip tuberculosis or pigmented villonodular synovitis was Suspected. However, gadolinium (Gd) enhanced MRI with fat suppression showed enhanced hypertrophic synovium and no enhanced nodular lesion in the synovium. Therefore, this case was diagnosed as synovial oeteochondromatosis of the hip joint. Synovectomy revealed hypertrophy of the synovium, and osteochondromatosis were seen matted within the synovium. There were no loose bodies in the joint space. However, this case achieved only a small improvement in his range of motion post-operatively. Microscopic examination, the synovium had many cartilaginous lesions, but there was few ossiferous lesion.We consider that Gd enhanced MRI with fat suppression is useful for the early diagnosis of synovial osteochondromatosis that has not been ossified. (Link to Publication Site) ● Publication site (DOI): 10.5035/nishiseisai.45.739 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679912059776 ● Search Scopus @ Elsevier (DOI): 10.5035/nishiseisai.45.739 (DOI: 10.5035/nishiseisai.45.739, CiNii: 1390282679912059776)
30.	Tetsuo Yamaguchi, Toru Hirano, Goichii Yoshida and Katsuro Iwasaki : Limb Function after Wide Resection of Quadriceps Muscle for Soft Tissue Sarcomas., Orthopedics & Traumatology, Vol.45, No.3, 917-921, 1996. (Summary) We studied the relationship between quadriceps muscular defects and limb functions in 12 patients with soft tissue sarcomas around the thigh who had undergone wide resections. To determine the degree of muscular defects, we divided the quadriceps muscle into 4 compartments, namely, rectus femoris, vastus medialis, vastus intermedius and vastus lateralis. The lower limb function was evaluated according to the criteria of the Musculo-Skeletal Tumor Society, Japan Orthopaedic Association. Twelve patients were divided into the following 3 groups, Group 1; 1 compartment, Group 2; 2 compartments, and Group 3; 3 and 4 compartments. Of 12 patients, Group 1, 2, and 3 included 6, 3 and 3 patients, respectively.The average total scores in Group 1, 2 and 3 were 24, 22 and 17 points out of 25 points, respectively. The decrease in the average total scores with the increase in muscular defects was affected by the scores in function, walking ability and gait appearance. This study suggests that limb function after resection of the quadriceps can be predicted. (Link to Publication Site) ● Publication site (DOI): 10.5035/nishiseisai.45.917 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001204935313280 ● Search Scopus @ Elsevier (DOI): 10.5035/nishiseisai.45.917 (DOI: 10.5035/nishiseisai.45.917, CiNii: 1390001204935313280)

Academic Paper (Unrefereed Paper):

1.	Haruki Nishino, Hiroshi Tateishi, Naohiro Hashimoto and Tetsuo Yamaguchi : 高齢大腸がん患者における腹腔鏡下切除術の術後炎症に関与する因子, 理学療法徳島, Vol.8, 41-44, 2019. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1521417755698183808 (CiNii: 1521417755698183808)
2.	井手衆哉, 角光宏, 櫛田学, Tetsuo Yamaguchi, 森本忠嗣 and 本川哲 : 慢性関節リウマチ患者に対するInsall-Burstein II型人工膝関節置換術の治療成績, Medical Journal of Nagasaki-Chuo National Hospital, Vol.3, No.1, 23-26, 2000. (Keyword) 関節リウマチ(外科的療法,予後)
3.	櫛田学, 本川哲, 角光宏, 前田和成, 井手衆哉 and Tetsuo Yamaguchi : 慢性関節リウマチ患者における人工膝関節置換術後のQOL評価, Medical Journal of Nagasaki-Chuo National Hospital, Vol.2, No.1, 18-20, 1999. (Keyword) 関節リウマチ(外科的療法)

Review, Commentary:

1.	Tetsuo Yamaguchi and Yoriko ATOMI : Can We Protect Aging-related Muscle Atrophy? : From the Aspect of Molecular Cellular Biology Based 'Beneficial Stress', The Journal of the Japanese Orthopaedic Association, Vol.81, No.10, 877-883, Oct. 2007. (Keyword) Aging / Skeletal muscle / α B-crystallin / MAPK / Hormesis (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520290884835318400 (CiNii: 1520290884835318400)

Proceeding of International Conference:

1.	Tetsuo Yamaguchi and Hiroaki Nishimoto : The effects of Shiko, a traditional Japanese training exercise: Towards the prevention of running injuries, British Journal of Sports Medicine, Vol.Supplement2, No.58, Mar. 2024.
2.	Tetsuo Yamaguchi : Effects of habitual jogging exercise on gene expressions in middle-aged human skeletal muscle, --- European College of Sports Science ---, FINAL PROGRAMME, 54, MALMO, Jun. 2015.
3.	Tetsuo Yamaguchi : Effects of sodium bicarbonate on fiber-type shift via calcium signaling in human skeletal myoblasts, --- American colledge of sports medicine ---, 61st annual meeting FINAL PROGRAM, 113, Orlando, May 2014.
4.	Tetsuo Yamaguchi and Naoshi Fukui : Distinct and additive effects of sodium bicarbonate and continuous mild heat stress on fiber type shift via calcineurin/NFAT cells pathway in human skeletal myoblasts, --- 2012 European College of Sport Science ---, The abstract, 28, Brugge, Jul. 2012.
5.	Tetsuo Yamaguchi : Continuous mild heat stress induces differentiation of human myoblasts, shifting fiber-type from fast to slow, --- International Conference & Exhibition on Cell Science & Stem Cell Research, ---, Journal of Cell and Science &Therapy, Vol.2, No.4, 115, Philadelphia, Nov. 2011.
6.	Tetsuo Yamaguchi and Yoriko Atomi : Mild heat shock induces differentiation of mammalian and avian myoblast, --- The 45th American Cell Biology Meeting ---, The Abstracts, 141, San Francisco, Dec. 2005.
7.	Tetsuo Yamaguchi and Yoriko Atomi : Age-related increase of insoluble, phosphorylated small heat shock proteins in human skeletal muscle, --- International Symposium on Life of Proteins ---, Awaji city, Oct. 2005.
8.	Tetsuo Yamaguchi and Yoriko Atomi : Mild heat shock induces differentiation of C2C12 myoblast, --- The 44th American Cell Biology Meeting ---, The abstract, 187, Washington DC, May 2004.
9.	Tetsuo Yamaguchi, Masaya Shiraishi and Satoshi Shirahama : The change in levels of joint markers in articular chondrocalcinosis with gonarthrosis, --- The 2nd International Conference on The Neuroendocrine immune Basis of the Rheumatic Disease ---, Genova, Sep. 2001.
10.	Tetsuo Yamaguchi, Masaya Shiraishi and Satoshi Shirahama : Human T-cell leukemia virus-I carriers and joint markers in synovial fluids of gonarthrosis, --- The 2nd International Conference on The Neuroendocrine immune Basis of the Rheumatic Disease ---, Genova, Sep. 2001.
11.	Tetsuo Yamaguchi and Satoru Motokawa : A study of loosening following hip arthroplasty among patients on long-term steroid use, --- British/Japanese Orthopedic Association Combined Congress ---, the abstracts, 10, London, Jun. 2001.
12.	Tetsuo Yamaguchi and Satoru Motokawa : The incidence and features of osteolysis among patients with different pathogenesis following arthroplasty, --- European League Against Rheumatism ---, The Scientific Abstracts, 61, Nice, Jun. 2000.

Proceeding of Domestic Conference:

1.	Tetsuo Yamaguchi, 西本浩章 and 大西純二 : 両側性の脛骨疲労骨折について, 日本臨床スポーツ医学会雑誌, Nov. 2022. (Keyword) 疲労骨折 / 脛骨 / スポーツ障害
2.	西本浩章 and Tetsuo Yamaguchi : 足趾または四股トレーニングが下肢機能に与える影響, 第88回日本体力医学会四国・四国地方会抄録集, Jun. 2022. (Keyword) 四股 / 足内在筋 / 傷害予防
3.	Tetsuo Yamaguchi, 西本浩章, Shoji Fukuta and 福井尚志 : Characteristics of gene expression in frozen shoulder and its association with shoulder joint range of motion, The Journal of the Japanese Orthopaedic Association, Vol.95, No.8, 1507, Oct. 2021.
4.	Haruki Nishino and Tetsuo Yamaguchi : 成人男性におけるACE及びACTN3遺伝子多型が体組成に与える影響, The Japanese Journal of Rehabilitation Medicine, s216, Aug. 2020.
5.	Masataka Watanabe and Tetsuo Yamaguchi : 腱板筋腹の加齢変化について;超音波画像を用いた検討, The Japanese Journal of Rehabilitation Medicine, s83, Jun. 2019.
6.	Tetsuo Yamaguchi, Shoji Fukuta and 福井尚志 : 拘縮肩における炎症性サイトカインとタンパク分解酵素の発現 -滑膜の部位別解析-, The Journal of the Japanese Orthopaedic Association, Vol.92, No.8, 1907, Oct. 2018.
7.	川道幸司, Naoto Suzue and Tetsuo Yamaguchi : 膝前十字靭帯再建術後における筋萎縮と変性, 日本臨床スポーツ医学会誌, Vol.24, No.4, S322, Nov. 2016.
8.	Tetsuo Yamaguchi : Effects of habitual exercise on myokine expression in middle-aged human skeletal muscle, The Journal of the Japanese Orthopaedic Association, Vol.90, No.8, 1754, Oct. 2016.
9.	Tohru Adachi and Tetsuo Yamaguchi : 運動による血糖変動と糖尿病リスクについて, 第77回日本体力医学会中国四国地方会抄録集, Jun. 2016.
10.	Tetsuo Yamaguchi : 筋肉のエイジング・アンチエイジングヒト筋芽細胞のストレス応答ミトコンドリアを中心に, The Journal of the Japanese Orthopaedic Association, Vol.88, No.8, S1580, Oct. 2014. (Keyword) mitochondria / 骨格筋 / アンチエイジング
11.	福井尚志, 田中信帆, 池田泰子 and Tetsuo Yamaguchi : 変形性膝関節症において血管内皮細胞増殖因子Aの活性阻害は治療効果を示すか予備的検討の結果, The Journal of the Japanese Orthopaedic Association, Vol.87, No.2, S468, Mar. 2013.
12.	福井尚志, 田中信帆, 池田泰子, Tetsuo Yamaguchi, 増田公男, 十字琢夫 and 森俊仁 : 変形性膝関節症においてVEGF-Aの活性阻害は関節液中のMMP-1の濃度を有意に低下させる, The Journal of the Japanese Orthopaedic Association, Vol.87, No.8, S1607, 2013.
13.	Tetsuo Yamaguchi and 福井尚志 : Sodium bicarbonateがヒト筋芽細胞の分化へ及ぼす影響について, The Journal of the Japanese Orthopaedic Association, Vol.87, No.8, S1601, 2013.
14.	福井尚志, 田中信帆, 池田泰子, Tetsuo Yamaguchi, 十字琢夫, 増田公男 and 森俊仁 : 変形性膝関節症においてVEGF-Aの活性阻害は滑膜病変を軽減することで治療効果を示す可能性がある, JOSKAS, Vol.38, No.4, 160, 2013. (Keyword) 滑膜治療成績変形性膝関節症(薬物療法) *Bevacizumab(治療的利用) Vascular Endothelial Growth Factor A(拮抗物質・阻害物質) ヒト
15.	福井尚志, 田中信帆, 池田泰子, Tetsuo Yamaguchi, 田代俊之 and 桂川陽三 : 変形性関節症では血管新生が滑膜病変を引き起こす重要な機序である, The Journal of the Japanese Orthopaedic Association, Vol.86, No.8, S1261, Aug. 2012. (Keyword) *滑膜
16.	福井尚志, 田中信帆, 池田泰子, Tetsuo Yamaguchi, 田代俊之 and 桂川陽三 : 変形性関節症では変性軟骨から荷重によって血管新生を誘導する因子が放出される, The Journal of the Japanese Orthopaedic Association, Vol.86, No.8, S1334, Aug. 2012. (Keyword) *変形性関節症
17.	Tetsuo Yamaguchi, 田中信帆 and 福井尚志 : 筋損傷を科学する持続的温度変化がヒト筋芽細胞の増殖・分化へ与える効果とその分子メカニズム, The Journal of the Japanese Orthopaedic Association, Vol.86, No.8, S1223, Aug. 2012. (Keyword) 温度
18.	福井尚志, 田中信帆, 和気昌弘, 池田泰子 and Tetsuo Yamaguchi : 変形性関節症では血管新生が滑膜病変を引き起こす, JOSKAS, Vol.37, No.4, 61, Jun. 2012. (Keyword) *滑膜
19.	Tetsuo Yamaguchi : 微妙な温度変化による骨格筋再生の変化, プログラム・抄録集, 3, Jun. 2012.
20.	田中信帆, 池田泰子, 和気昌弘, Tetsuo Yamaguchi and 福井尚志 : 変形性関節症では変性軟骨から荷重によって血管新生を誘導する因子が放出される, JOSKAS, Vol.37, No.4, 61, Jun. 2012. (Keyword) *変形性関節症
21.	鈴木孝昌, 田邊思帆里, Tetsuo Yamaguchi and 鈴木和博 : MYBPC2 はヒト骨格筋筋芽細胞の筋分化マーカーとなる, 再生医療, Vol.11, 241, May 2012.
22.	Tetsuo Yamaguchi, 大森舞子, 田中信帆, 和気昌弘 and 福井尚志 : 温度変化によるヒト骨格筋筋芽細胞の分化制御, The Journal of the Japanese Orthopaedic Association, Vol.85, No.8, S1118, Aug. 2011. (Keyword) temperature
23.	福井尚志, 田中信帆, 石田暁, 池田泰子, Tetsuo Yamaguchi, 宮本恵成, 田代俊之 and 桂川陽三 : 変形性関節症では軟骨変性部においてIGFシグナルの低下によって基質産生が低下している, The Journal of the Japanese Orthopaedic Association, Vol.85, No.8, S1236, Aug. 2011. (Keyword) シグナルトランスダクション
24.	Tetsuo Yamaguchi, 大森舞子, 田中信帆, 和気昌弘, 池田泰子, 宮本恵成, 田代俊之, 桂川陽三, 沢辺元司 and 福井尚志 : 変形性関節症における軟骨変性には局所的なTIMPの発現低下が関与する, JOSKAS, Vol.36, No.4, 31, Jun. 2011. (Keyword) *変形性関節症(合併症)
25.	田中信帆, 石田暁, 大森舞子, 和気昌弘, 池田泰子, Tetsuo Yamaguchi, 宮本恵成, 田代俊之, 桂川陽三 and 福井尚志 : 変形性関節症では軟骨変性部でIGFシグナルの低下によって基質産生が低下している, JOSKAS, Vol.36, No.4, 31, Jun. 2011. (Keyword) Insulin-Like Growth Factor I
26.	福井尚志, 山根昌治, 田中信帆, 田中こなぎ, 池田泰子, 増田理亜子 and Tetsuo Yamaguchi : 複数の既知バイオマーカーの組み合わせによる変形性膝関節症の病態評価の試み, JOSKAS, Vol.36, No.4, 32, Jun. 2011. (Keyword) *生物学的マーカー(血液,尿)
27.	Tetsuo Yamaguchi, 大森舞子, 田中信帆, 和気昌弘 and 福井尚志 : 変形性関節症における軟骨変性には局所的なTIMPの発現低下が関与する, 第24回日本軟骨代謝学会プログラム・抄録集, p92, Mar. 2011.
28.	Tetsuo Yamaguchi, 田中信帆, 大森舞子, 和気昌弘, 池田泰子, 宮本恵成, 田代俊之, 桂川陽三, 沢辺元司 and 福井尚志 : 変形性関節症における軟骨変性には局所的なTIMPの発現低下が関与する, The Journal of the Japanese Orthopaedic Association, Vol.84, No.8, S1233, Aug. 2010. (Keyword) *変形性関節症(病因)
29.	Tetsuo Yamaguchi, 田中信帆, 池田泰子, 宮本恵成, 沢辺元司, 田代俊之, 桂川陽三 and 福井尚志 : 変形性膝関節症では滑膜細胞によって関節液中にMMP-1，2，3が供給される, JOSKAS, Vol.35, No.4, 150, Jun. 2010. (Keyword) *滑液
30.	Yoriko Atomi, Eri Fujita-Ohto, Tetsuo Yamaguchi, Takashi Sakurai and Yoshinobu Fujita : 1P148 Analysis of dynamic interaction of aB-crystallin with Z-disc protein in beating cardiac myocyte(Muscle-muscle proteins and contraction,Oral Presentations), Seibutsu Butsuri, Vol.47, No.SUPPLEMENT_1, 60, Nov. 2007. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001206541179264 (CiNii: 1390001206541179264)
31.	角光宏, 藤本勝也, 井手衆哉, Tetsuo Yamaguchi, 森本忠嗣 and 本川哲 : 自家骨軟骨移植を併用した橈骨遠位端粉砕骨折の治療経験, Japanese Journal of National Medical Services, Vol.54, 489, Oct. 2000. (Keyword) 自家移植
32.	Tetsuo Yamaguchi, 井手衆哉, 櫛田学, 角光宏, 森本忠嗣 and 本川哲 : The Relationship between Femoral Shape in Plain X-ray and Bone Mineral Density of Femur and Lumbar Spine, The Journal of the Japanese Orthopaedic Association, Vol.74, No.8, 1396, Aug. 2000. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1570291224406679296 (CiNii: 1570291224406679296)
33.	井手衆哉, 角光宏, 櫛田学, Tetsuo Yamaguchi and 本川哲 : RA患者における膝関節周囲骨密度, The Ryumachi, Vol.40, No.2, 426, Apr. 2000. (Keyword) 関節リウマチ
34.	S. IDE, 角光宏, 櫛田学, Tetsuo Yamaguchi, 森本忠嗣 and 本川哲 : Effect of PTHrP on Bone Mass of Patient with Rheumatoid Arthritis, The Journal of the Japanese Orthopaedic Association, Vol.74, No.3, 799, Mar. 2000. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1570291224418184704 (CiNii: 1570291224418184704)
35.	Tetsuo Yamaguchi, 井手衆哉, 森本忠嗣, 櫛田学, 角光宏 and 本川哲 : The Relationship between Hip Arthroplasty and Aseptic Loosening in Long-term Steroid Users, The Journal of the Japanese Orthopaedic Association, Vol.74, No.2, 456, Feb. 2000. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1571417124313196544 (CiNii: 1571417124313196544)
36.	Tetsuo Yamaguchi, 井手衆哉, 櫛田学, 前田和成 and 角光宏 : Osteonics型人工股関節の術後成績 : ステム側について, 第96回西日本整形・災害外科学会抄録集, 29, Nov. 1999.
37.	森本忠嗣, Tetsuo Yamaguchi, 井手衆哉, 櫛田学, 角光宏 and 本川哲 : 稀な合併症を有するKienboeck病の2例, Orthopedics & Traumatology, Vol.48, No.Suppl.2, 58, Oct. 1999. (Keyword) 月状骨(奇形・位置形態異常)
38.	櫛田学, 本川哲, 角光宏, 井手衆哉 and Tetsuo Yamaguchi : 非外傷性前骨間神経麻痺の治療, Japanese Journal of National Medical Services, Vol.53, 250, Oct. 1999. (Keyword) 創傷と損傷
39.	角光宏, 櫛田学, 井手衆哉, Tetsuo Yamaguchi, 前田和成, 本川哲, 今村宏太郎, 長谷芳文 and 貝田英二 : Kienbock 病における病期分類 : 橈骨骨切り術術後成績からみた妥当性と問題点の検討, The Journal of the Japanese Orthopaedic Association, Vol.73, No.3, 809, Mar. 1999. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1572261549988466176 (CiNii: 1572261549988466176)
40.	Tetsuo Yamaguchi, 井手衆哉, 櫛田学, 前田和成, 角光宏 and 本川哲 : 病態からみた人工股関節置換術後の Osteolysis に関する検討 : ステム側について, The Journal of the Japanese Orthopaedic Association, Vol.73, No.3, 993, Mar. 1999. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1571980075012296960 (CiNii: 1571980075012296960)
41.	Tetsuo Yamaguchi, YOSHIHISA YAMAGUCHI and MASAYUKI YAMADA : FRACTURE OF THE ULNAR STYLOID PROCESS IN A SOFTBALL PLAYER, 日本整形外科スポーツ医学会雑誌 = Japanese journal of orthopaedic sports medicine, Vol.18, No.3, 304, Sep. 1998. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1572543025124932480 (CiNii: 1572543025124932480)
42.	Tetsuo Yamaguchi, 山口善久 and 山田正幸 : 体格指数(body Mass Index)と足関節可動域, 学会雑誌抄録号, Vol.18, No.3, 87, Sep. 1998.
43.	Tetsuo Yamaguchi, 真島隆三, 弦本敏行, 楢林葉子 and 岩永斉 : 嚢胞性線維性骨炎を呈した成人T細胞白血病の1例, 日本整形外科學會雜誌, Vol.71, No.6, 1270, Jul. 1997.
44.	Tetsuo Yamaguchi, 真島隆三, 弦本敏行, 楢林葉子 and 岩永斉 : 病的骨折を呈した成人T細胞白血病の1例, 第92回西日本整形・災害外科学会学会抄録集, 76, Nov. 1996.
45.	Tetsuo Yamaguchi, 伊藤信之, 衛藤正雄, 朝長匡 and 原田真一 : 肩関節における滑液包内遊離体の2例, 第91回西日本整形・災害外科学会, 学会抄録集, 14, Jun. 1996.
46.	Tetsuo Yamaguchi, 平野徹, 吉田伍一 and 岩崎勝郎 : 大腿四頭筋を広範囲切除した悪性軟部腫瘍症例の患肢機能, 第90回西日本整形・災害外科学会学会抄録集, 35, Dec. 1995.

Et cetera, Workshop:

1.	Tetsuo Yamaguchi and 跡見順子 : マイルドな熱ストレスが筋分化を促進する, Jan. 2006.

Report:

1.	Mitsuhiro Sato, Hajime Miura, Masayuki Satake, Tetsuo Yamaguchi, teppei yukizane and Kentaro Nakatsuka : 三好市子どもの体力向上に関する支援環境デザイン小学校視察調査・保護者質問紙調査報告書, 三好市・徳島大学地域連携調査研究, 1-32, Mar. 2015. (Keyword) 子どもの体力向上
2.	Tetsuo Yamaguchi : 24. 温度が骨格筋筋芽細胞の分化へ及ぼす影響について, 独立行政法人国立相模原病院臨床研究センター研究報告書(平成23年度), Aug. 2012.
3.	Tetsuo Yamaguchi : 骨格筋損傷∼筋再生加速化への挑戦, 平成23年度公益法人ヤマハ発動機スポーツ振興財団年間事業報告書, May 2012.
4.	Tetsuo Yamaguchi : Distinct and additive effects of sodium bicarbonate and continuous mild heat stress on fiber type shift via calcineurin/NFAT cells pathway in human skeletal myoblasts, ライフサイエンス振興財団研究報告書, 2012.
5.	Tetsuo Yamaguchi : 骨格筋損傷∼温度による治癒機転の制御, 整形災害外科研究助成財団研究報告書, 2012.
6.	Tetsuo Yamaguchi : 変形性関節症における軟骨変性には局所的なTIMPの発現低下が関与する, 独立行政法人国立相模原病院臨床研究センター研究報告書(平成22年度), Aug. 2011.
7.	Tetsuo Yamaguchi : 横紋筋の活動依存性維持の分子機構を探る-哺乳類筋細胞におけるGFP融合ストレスタンパク質(αB- crystallin・HSP70)のダイナミクスと機能局在連関の解析から, 2003.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

Development of an educational application for the prevention of running disorders (Project/Area Number: 20K11488 )
Molecular mechanisms of site-related differences of sarcopenia in Japanese women (Project/Area Number: 24650342 )
Changes in expression of proteinases and tissue inhibitors of metalloproteinases in advance of osteoarthritis (Project/Area Number: 23592241 )
Search by Researcher Number (80569731)