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Tokushima University > Graduate School of Biomedical Sciences > 薬学域 > Pharmaceutical Science > Pharmaceutical Life Sciences > Department of Pharmacokinetics and Biopharmaceutics > (Files for researchmap) [PDF manual] [Auto-propagate to researchmap]

Research Activity

His Web Page

Field of Study

Subject of Study

Book / Paper

Book:

1. Tatsuhiro Ishida and Hidenori Andou :
ドラッグデリバリーシステム(DDS),
京都廣川書店, 2015.

Academic Paper (Judged Full Paper):

1. Takuma Takayama, Taro Shimizu, Lila Selim Ahmed Ali Abu Amr, Yuki Kanazawa, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
Adjuvant antitumor immunity contributes to the overall antitumor effect of PEGylated liposomal doxorubicin (Doxil®) in C26 tumor-bearing immunocompetent mice,
Pharmaceutics, Vol.12, No.10, 990, 2020.
(DOI: 10.3390/pharmaceutics12100990)
2. Shota Fuimoto, Naoki Muguruma, Michiyasu Nakao, Hidenori Andou, Takanori Kashihara, Yoshihiko Miyamoto, Koichi Okamoto, Shigeki Sano, Tatsuhiro Ishida, Yasushi Sato and Tetsuji Takayama :
Indocyanine green-labeled dasatinib as a new fluorescent probe for molecular imaging of gastrointestinal stromal tumors.,
Journal of Gastroenterology and Hepatology, Vol.in press, 2020.
(DOI: 10.1111/jgh.15281,   PubMed: 32989784)
3. Elhewan Emam Elsadek Emam Ali Nehal, Emam Emam Abdallah Sherif, Lila Selim Ahmed Ali Abu Amr, Taro Shimizu, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
Pegfilgrastim (PEG-G-CSF) induces anti-polyethylene glycol (PEG) IgM via a T cell-dependent mechanism,
Biological & Pharmaceutical Bulletin, Vol.43, No.9, 1393-1397, 2020.
(DOI: 10.1248/bpb.b20-00345,   PubMed: 32879214)
4. A Nguyen, Hidenori Andou, R Böttger, K K Viswanadham, E Rouhollahi, Tatsuhiro Ishida and S Li :
Utilization of Click Chemistry to Study the Effect of Poly(ethylene) Glycol Molecular Weight on the Self-Assembly of PEGylated Gambogic Acid Nanoparticles for the Treatment of Rheumatoid Arthritis,
Biomaterials Science, Vol.8, No.16, 4626-4637, 2020.
(DOI: 10.1039/d0bm00711k,   PubMed: 32700691)
5. Elhewan Emam Elsadek Emam Ali Nehal, Eri Hondoh, Taro Shimizu, Haruka Takata, Lila Selim Ahmed Ali Abu Amr, Emam Emam Abdallah Sherif, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
Impact of pre-existing or induced anti-PEG IgM on the pharmacokinetics of peginterferon alfa-2a (Pegasys®) in mice,
Molecular Pharmaceutics, Vol.17, No.8, 2964-2970, 2020.
(DOI: 10.1021/acs.molpharmaceut.0c00366,   PubMed: 32519877)
6. M Sayed M El, Haruka Takata, Taro Shimizu, Yoshino Kawaguchi, Lila Selim Ahmed Ali Abu Amr, Elhewan Emam Elsadek Emam Ali Nehal, E Alaaeldin, Yu Ishima, Hidenori Andou, A Kamal, A H Sarhan and Tatsuhiro Ishida :
Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes: Appearance of an unexplained mechanism in the ABC phenomenon,
Journal of Controlled Release, Vol.323, 102-109, 2020.
(DOI: 10.1016/j.jconrel.2020.04.011,   PubMed: 32278827,   Elsevier: Scopus)
7. Nehal Ali Emam Elsadek Emam Elhewan, Amr Abu Ali Ahmed Selim Lila, Sherif Abdallah Emam Emam, Taro Shimizu, Haruka Takata, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice,
European Journal of Pharmaceutics and Biopharmaceutics, Vol.152, 56-62, 2020.
(DOI: 10.1016/j.ejpb.2020.04.026,   PubMed: 32376372)
8. Hidenori Andou, Noriko Saito-Tarashima, Lila Selim Ahmed Ali Abu Amr, Nozomi Kinjoh, Taro Shimizu, Yu Ishima, Noriaki Minakawa and Tatsuhiro Ishida :
A unique gene-silencing approach, using an intelligent RNA expression device (iRed), results in minimal immune stimulation when given by local intrapleural injection in malignant pleural mesothelioma,
Molecules, Vol.25, No.7, 1725, 2020.
(DOI: 10.3390/molecules25071725,   PubMed: 32283709,   Elsevier: Scopus)
9. Hidenori Andou, K Eshima and Tatsuhiro Ishida :
Neutralization of acidic tumor microenvironment (TME) with daily oral dosing of sodium potassium citrate (K/Na Citrate) increases therapeutic effect of anti-cancer agent in pancreatic cancer xenograft mice model,
Biological & Pharmaceutical Bulletin, 2020.
10. Taro Shimizu, Mizuki Awata, Lila Selim Ahmed Ali Abu Amr, Chihiro Yoshioka, Yoshino Kawaguchi, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
Complement activation induced by PEG enhances humoral immune responses against antigens encapsulated in PEG-modified liposomes,
Journal of Controlled Release, 2020.
(DOI: 10.1016/j.jconrel.2020.10.033)
11. Tasuku Torao, Miyuki Mimura, Yasufumi Ohshima, Kohki Fujikawa, Mahadi Hasan, Tatsuharu Shimokawa, Naoshi Yamazaki, Hidenori Andou, Tatsuhiro Ishida, Tatsuya Fukuta, Tamotsu Tanaka and Kentaro Kogure :
Characteristics of unique endocytosis induced by weak current for cytoplasmic drug delivery,
International Journal of Pharmaceutics, Vol.576, 119010, 2020.
(Tokushima University Institutional Repository: 114728,   DOI: 10.1016/j.ijpharm.2019.119010)
12. Emam Emam Abdallah Sherif, Lila Selim Ahmed Ali Abu Amr, Elhewan Emam Elsadek Emam Ali Nehal, Hidenori Andou, Taro Shimizu, Keiichiro Okuhira, Yu Ishima, M Mahdy, E Ghazy and Tatsuhiro Ishida :
Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues,
European Journal of Pharmaceutics and Biopharmaceutics, Vol.145, 27-34, 2019.
(DOI: 10.1016/j.ejpb.2019.10.005,   PubMed: 31629787,   Elsevier: Scopus)
13. Hidenori Andou, M Fukushima, K Eshima, Taichi Hasui, Taro Shimizu, Yu Ishima, C Huang, H Wada and Tatsuhiro Ishida :
A novel intraperitoneal therapy for gastric cancer with DFP-10825, a unique RNAi therapeutic targeting thymidylate synthase, in peritoneally disseminated xenograft model,
Cancer Medicine, Vol.8, No.17, 7313-7321, 2019.
(Tokushima University Institutional Repository: 115036,   DOI: 10.1002/cam4.2598,   PubMed: 31609087)
14. Taro Shimizu, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
PEG修飾リポソームに対する免疫応答,
人工血液, Vol.27, 37-43, 2019.
15. Hiroyuki Koide, Tatsuya Fukuta, Anna Okishim, Saki Ariizumi, Chiaki Kiyokawa, Hiroki Tsuchida, Masahiko Nakamoto, Keiichi Yoshimatsu, Hidenori Andou, Takehisa Dewa, Tomohiro Asai, Naoto Oku, Yu Hoshino and Kenneth J. Shea :
Engineering the binding kinetics of synthetic polymer nanoparticles for siRNA delivery,
Biomacromolecules, Vol.20, No.10, 3648-3657, 2019.
(DOI: 10.1021/acs.biomac.9b00611,   PubMed: 31518109,   Elsevier: Scopus)
16. Hidenori Andou, Lila Selim Ahmed Ali Abu Amr, M Fukushima, Rie Matsuoka, Taro Shimizu, Keiichiro Okuhira, Yu Ishima, C Huang, H Wada and Tatsuhiro Ishida :
A simplified method for manufacturing RNAi therapeutics for local administration,
International Journal of Pharmaceutics, Vol.564, 256-262, 2019.
(DOI: 10.1016/j.ijpharm.2019.04.054,   PubMed: 31015002,   Elsevier: Scopus)
17. Mayumi Ikeda, Yu Ishima, VTG Chuang, Maki Sakai, Hiroki Osafune, Hidenori Andou, Taro Shimizu, Keiichiro Okuhira, H Watanabe, T Maruyama, M Otagiri, T Akaike and Tatsuhiro Ishida :
Distribution of Polysulfide in Human Biological Fluids and Their. Association with Amylase and Sperm Activities,
Molecules, Vol.24, No.9, 1689, 2019.
(DOI: 10.3390/molecules24091689,   PubMed: 31052207,   Elsevier: Scopus)
18. Taro Shimizu, Lila Selim Ahmed Ali Abu Amr, Mizuki Awata, Yukiyo Kubo, Yu Mima, Yosuke Hashimoto, Hidenori Andou, Keiichiro Okuhira, Yu Ishima and Tatsuhiro Ishida :
A cell assay for detecting anti-PEG immune response against PEG-modified therapeutics,
Pharmaceutical Research, Vol.35, No.11, 223, 2018.
(DOI: 10.1007/s11095-018-2505-3,   PubMed: 30280273,   Elsevier: Scopus)
19. Emam Emam Abdallah Sherif, Hidenori Andou, Lila Selim Ahmed Ali Abu Amr, Taro Shimizu, Keiichiro Okuhira, Yu Ishima, M Mahdy, F Ghazy, I Sagawa and Tatsuhiro Ishida :
Liposome co-incubation with cancer cells secreted exosomes (extracellular vesicles) with different proteins expressions and different uptake pathways,
Scientific Reports, Vol.8, No.1, 14493, 2018.
(Tokushima University Institutional Repository: 114955,   DOI: 10.1038/s41598-018-32861-w,   PubMed: 30262875,   Elsevier: Scopus)
20. Emam Emam Abdallah Sherif, Hidenori Andou, Lila Selim Ahmed Ali Abu Amr, Shinya Kobayashi, Taro Shimizu, Keiichiro Okuhira, Yu Ishima and Tatsuhiro Ishida :
Doxorubicin expands in vivo secretion of circulating exosome in mice,
Biological & Pharmaceutical Bulletin, Vol.41, No.7, 1078-1083, 2018.
(DOI: 10.1248/bpb.b18-00202,   PubMed: 29962402,   Elsevier: Scopus)
21. Emam Emam Abdallah Sherif, Hidenori Andou, Lila Selim Ahmed Ali Abu Amr, Taro Shimizu, Masami Ukawa, Keiichiro Okuhira, Yu Ishima, A M Mahdy, S F Ghazy and Tatsuhiro Ishida :
A novel strategy to increase the yield of exosomes (extracellular vesicles) for an expansion of basic research,
Biological & Pharmaceutical Bulletin, Vol.41, No.5, 733-742, 2018.
(DOI: 10.1248/bpb.b17-00919,   PubMed: 29709910,   Elsevier: Scopus)
22. Hidenori Andou, Lila Selim Ahmed Ali Abu Amr, Masao Tanaka, Yusuke Doi, Yasuko Terada, Naoto Yagi, Taro Shimizu, Keiichiro Okuhira, Yu Ishima and Tatsuhiro Ishida :
Intratumoral visualization of oxaliplatin within a liposomal formulation using X-ray fluorescence spectrometry,
Molecular Pharmaceutics, Vol.15, No.2, 403-409, 2018.
(DOI: 10.1021/acs.molpharmaceut.7b00762,   PubMed: 29287147,   Elsevier: Scopus)
23. Hidenori Andou, Lila Selim Ahmed Ali Abu Amr, Munehira Kawanishi, Taro Shimizu, Keiichiro Okuhira, Yu Ishima and Tatsuhiro Ishida :
Reactivity of IgM antibodies elicited by PEGylated liposomes or PEGylated lipoplexes against auto and foreign antigens,
Journal of Controlled Release, Vol.270, 114-119, 2018.
(DOI: 10.1016/j.jconrel.2017.12.002,   PubMed: 29217175,   Elsevier: Scopus)
24. Hidenori Andou and Tatsuhiro Ishida :
放射光施設(SPring-8)における蛍光X線分析法を用いたオキサリプラチン腫瘍内分布解析,
Journal of Pharmaceutical Science and Technology, Japan, Vol.78, No.1, 1-6, 2018.
(DOI: 10.14843/jpstj.78.28,   CiNii: 130006301812)
25. Kentaro Nishida, Misaki Kashiwagi, Shunsuke Shiba, Kiwamu Muroki, Akihiro Ohishi, Yusuke Doi, Hidenori Andou, Tatsuhiro Ishida and Kazuki Nagasawa :
Liposomalization of oxaliplatin induces skin accumulation of it, but negligible skin toxicity,
Toxicology and Applied Pharmacology, Vol.337, 76-84, 2017.
(DOI: 10.1016/j.taap.2017.10.006,   PubMed: 29054682,   Elsevier: Scopus)
26. Taro Shimizu, Lila Selim Ahmed Ali Abu Amr, Miho Nishio, Yusuke Doi, Hidenori Andou, Masami Ukawa, Yu Ishima and Tatsuhiro Ishida :
Modulation of antitumor immunity contributes to the enhanced therapeutic efficacy of liposomal oxaliplatin in mouse model,
Cancer Science, Vol.108, No.9, 1864-1869, 2017.
(Tokushima University Institutional Repository: 112372,   DOI: 10.1111/cas.13305,   PubMed: 28643902)
27. Alaaeldin Eman, Lila Selim Ahmed Ali Abu Amr, Hidenori Andou, M Fukushima, C Huang, H Wada, H.A Sarhan, K.A Khaled and Tatsuhiro Ishida :
Co-administration of liposomal l-OHP and PEGylated TS shRNA-lipoplex: A novel approach to enhance anti-tumor efficacy and reduce the immunogenic response to RNAi molecules,
Journal of Controlled Release, Vol.255, 210-217, 2017.
(DOI: 10.1016/j.jconrel.2017.04.040,   PubMed: 28461099)
28. Mayumi Ikeda, Yu Ishima, Akitomo Shibata, Victor T.G. Chuang, Tomohiro Sawa, Hideshi Ihara, Hiroshi Watanabe, Ming Xian, Yuya Ouchi, Taro Shimizu, Hidenori Andou, Masami Ukawa, Tatsuhiro Ishida, T Akaike, M Otagiri and T Maruyama :
Quantitative determination of polysulfide in albumins, plasma proteins and biological fluid samples using a novel combined assays approach,
Analytica Chimica Acta, Vol.969, 18-25, 2017.
(DOI: 10.1016/j.aca.2017.03.027,   PubMed: 28411626,   Elsevier: Scopus)
29. Yu Mima, Lila Selim Ahmed Ali Abu Amr, Taro Shimizu, Masami Ukawa, Hidenori Andou, Yasuko Kurata and Tatsuhiro Ishida :
Ganglioside inserted into PEGylated liposome attenuates anti-PEG immunity,
Journal of Controlled Release, Vol.250, 20-26, 2017.
(DOI: 10.1016/j.jconrel.2017.01.040,   PubMed: 28179196,   Elsevier: Scopus)
30. Takuma Takayama, Masami Ukawa, Yuki Kanazawa, Hidenori Andou, Taro Shimizu and Tatsuhiro Ishida :
Hydrodynamic tail vein injection as a simple tool for yielding extended transgene expression in solid tumors.,
Biological & Pharmaceutical Bulletin, Vol.39, No.9, 1555-1558, 2016.
(DOI: 10.1248/bpb.b16-00283,   PubMed: 27582335,   Elsevier: Scopus)
31. Masami Ukawa, Yukako Fujiwara, Hidenori Andou, Taro Shimizu and Tatsuhiro Ishida :
Hepatic tumor metastases cause enhanced PEGylated liposome uptake by Kupffer cells,
Biological & Pharmaceutical Bulletin, Vol.39, No.2, 215-220, 2016.
(DOI: 10.1248/bpb.b15-00611,   PubMed: 26830481,   Elsevier: Scopus)
32. Noriko Saito-Tarashima, Hidenori Andou, Takamitsu Kojima, Nozomi Kinjo, Yosuke Hashimoto, Kazuhiro Furukawa, Tatsuhiro Ishida and Noriaki Minakawa :
Gene silencing using 4'-thioDNA as an artificial template to synthesize short-hairpin RNA without inducing a detectable innate immune response,
Molecular Therapy. Nucleic Acids, Vol.5, e274, 2016.
(Tokushima University Institutional Repository: 110894,   DOI: 10.1038/mtna.2015.48,   PubMed: 26730811,   Elsevier: Scopus)
33. Hiroyuki Nakamura, Lila Selim Ahmed Ali Abu Amr, Miho Nishio, Masao Tanaka, Hidenori Andou, Hiroshi Kiwada and Tatsuhiro Ishida :
Intra-tumor distribution of PEGylated liposome upon repeated injection: No possession by prior dose,
Journal of Controlled Release, Vol.220, 406-413, 2015.
(DOI: 10.1016/j.jconrel.2015.11.002,   PubMed: 26548975,   Elsevier: Scopus)
34. Hidenori Andou, Sakiko Kobayashi, Lila Selim Ahmed Ali Abu Amr, N Eldin Essam, Chihiro Katoh, Taro Shimizu, Masami Ukawa, Kazuyoshi Kawazoe and Tatsuhiro Ishida :
Advanced therapeutic approach for the treatment of malignant pleural mesothelioma via the intrapleural administration of liposomal pemetrexed,
Journal of Controlled Release, Vol.220, 29-36, 2015.
(DOI: 10.1016/j.jconrel.2015.10.019,   PubMed: 26476173,   Elsevier: Scopus)
35. Taro Shimizu, Yu Mima, Yosuke Hashimoto, Masami Ukawa, Hidenori Andou, Hiroshi Kiwada and Tatsuhiro Ishida :
Anti-PEG IgM and complement system are required for the association of second doses of PEGylated liposomes with splenic marginal zone B cells,
Immunobiology, Vol.220, No.10, 1151-1160, 2015.
(DOI: 10.1016/j.imbio.2015.06.005,   PubMed: 26095176,   Elsevier: Scopus)
36. Noriko Saito-Tarashima, Tatsuya Sumitomo, Hidenori Andou, Kazuhiro Furukawa, Tatsuhiro Ishida and Noriaki Minakawa :
Synthesis of DNA fragments containing 2-deoxy-4-selenonucleoside units using DNA polymerases: comparison of dNTPs with O, S and Se at the 4-position in replication Org,
Organic & Biomolecular Chemistry, Vol.13, No.25, 6949-6952, 2015.
(DOI: 10.1039/c5ob00941c,   PubMed: 26053864,   Elsevier: Scopus)

Review, Commentary:

1. Hidenori Andou and Tatsuhiro Ishida :
An RNAi therapeutic, DFP-10825, for intraperitoneal and intrapleural malignant cancers,
Advanced Drug Delivery Reviews, Aug. 2020.
(DOI: 10.1016/j.addr.2020.08.002,   PubMed: 32781056)
2. Hidenori Andou and Tatsuhiro Ishida :
臨床応用可能な体腔内投与型RNAi 製剤(DFP-10825)の開発と難治性がんに対する治療,
MEDCHEM NEWS, Vol.30, No.1, 19-24, Feb. 2020.
3. Hidenori Andou, Taro Shimizu and Tatsuhiro Ishida :
リポソームDDS 製剤開発における免疫系の制御と動態解析の重要性,
Oleoscience, Vol.20, No.2, 71-76, Feb. 2020.
(DOI: 10.5650/oleoscience.20.71,   CiNii: 130007795350)
4. Hidenori Andou, 田島 健次, 松島 得雄 and Tatsuhiro Ishida :
ナノフィブリル化バクテリアセルロース(Fibnano)を用いた腹腔内投与型がん治療製剤への応用,
Cellulose Communications, Vol.26, No.4, 173-177, Dec. 2019.
5. 田島 健次, 小瀬 亮太, 松島 得雄, Tatsuhiro Ishida and Hidenori Andou :
フルーツ由来新奇酢酸菌によるナノセルロースの合成とその応用,
日本醸造協会誌, Vol.114, No.9, 540-549, Sep. 2019.
(CiNii: 40022026601)
6. Masami Ukawa, Hidenori Andou, Taro Shimizu and Tatsuhiro Ishida :
Pharmaceutics of Nanoparticles,
Nanomaterials in Pharmacology, 219-238, Nov. 2015.
(DOI: 10.1007/978-1-4939-3121-7_11)

Proceeding of International Conference:

1. Taro Shimizu, Kohga Miyahara, G Kozma, Hidenori Andou, Yu Ishima, J Szebeni and Tatsuhiro Ishida :
Pre-treatment with Doxebo suppresses anti-PEG IgM immune responses through PEG-specific immune tolerance,
17th International Symposium on Blood Substitutes & Oxygen Therapeutics, Nara, Nov. 2019.
2. Sherif Abdallah Emam Emam, Hidenori Andou, Taro Shimizu and Tatsuhiro Ishida :
The impact of cell-type tropism on the intratumor accumulation of exosomes derived from cancer cells,
Liposome Research Days 2019, Sapporo, Sep. 2019.
3. Maho Tagami, Hidenori Andou, Ai Ikeda, K Eshima, C.L Huang, H Wada and Tatsuhiro Ishida :
Enhanced therapeutic efficacy of liposomal weak-base anticancer drugs by daily oral administration of sodium bicarbonate,
Liposome Research Days 2019, Sapporo, Sep. 2019.
4. Yuna Shimazaki, Hidenori Andou, Taro Shimizu, Yu Ishima and Tatsuhiro Ishida :
Immunization method to obtain antigen-specific antibodies by antigen delivery to splenic marginal zone B cells using PEGylated liposomes,
Liposome Research Days 2019, Sapporo, Sep. 2019.
5. Emam Emam Abdallah Sherif, Hidenori Andou, Lila Selim Ahmed Ali Abu Amr, Yu Ishima, A M Mahdy, S F Ghazy and Tatsuhiro Ishida :
The effect of liposome co-incubation with cancer cells on the secretion, uptake propensity and expression of certain surface proteins of cancer cell-derived exosomes (extracellular vesicles),
2018 CRS Annual Meeting & Exposition, New York, Jul. 2018.
6. Tatsuhiro Ishida, Hidenori Andou, M Fukushima, C.L Huang and H Wada :
An industrial method of manufacturing a novel RNAi anticancer drug, DFP-10825, for the treatment of peritoneal disseminated gastric cancer,
AACR Annual Meeting 2017, Washington, D.C., Apr. 2017.
7. Nozomi Kinjoh, Hidenori Andou, Noriko Saito-Tarashima, Noriaki Minakawa and Tatsuhiro Ishida :
Targeted gene silencing by introduction of intelligent RNA expression device (iRed),
Liposome Advances 2015, London, Dec. 2015.
8. Noriko Saito-Tarashima, Kinjo Nozomi, Kojima Takamitsu, Hidenori Andou, Tatsuhiro Ishida and Noriaki Minakawa :
Gene silencing via RNA interference (RNAi) machinery using 4'-thioDNA as an artificial template,
The 42nd International Symposium on Nucleic Acids Chemistry, Himeji, Sep. 2015.

Proceeding of Domestic Conference:

1. Maki Sakai, Hidenori Andou, Taro Shimizu, Yu Ishima and Tatsuhiro Ishida :
ストレプトゾトシン誘発Ⅰ型糖尿病モデルマウスにおける血清活性イオウ分子の変動,
第93回日本生化学会大会, Sep. 2020.
2. Hiroki Osafune, Mayumi Ikeda, Hidenori Andou, Taro Shimizu, Yu Ishima and Tatsuhiro Ishida :
生体液中の活性イオウ分子種含有タンパク質の同定と生理学的意義の解明,
第93回日本生化学会大会, Sep. 2020.
3. Yuki Matsugi, Taro Shimizu, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
抗がん剤搭載脾臓細胞によるがん細胞障害性評価に関する検討,
第36回日本DDS学会学術集会, Aug. 2020.
4. Chika Sakamoto, Taro Shimizu, Hidenori Andou, Yu Ishima, 小林 勝則, 石橋 賢樹, 三輪 泰司, 濱本 英利 and Tatsuhiro Ishida :
イオン液体を用いたsiRNAの経皮送達による新規乾癬治療法の開発,
第36回日本DDS学会学術集会, Aug. 2020.
5. Yoshino Kawaguchi, Mizuki Awata, Yuna Shimazaki, Chihiro Yoshioka, Taro Shimizu, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
ヒドロキシ末端PEG修飾リポソームによる抗原刺激を利用した新規B細胞ワクチンの開発,
第36回日本DDS学会学術集会, Aug. 2020.
6. Sesshu Yamaguchi, Yuna Shimazaki, Hidenori Andou, Taro Shimizu, Yu Ishima and Tatsuhiro Ishida :
脾臓辺縁帯B細胞への抗原送達による抗体産生誘導技術の開発,
日本薬剤学会第35年会, May 2020.
7. MARUYAMA Atsuya, Hidenori Andou, 三輪 泰司, 濱本 英利, Taro Shimizu, Yu Ishima and Tatsuhiro Ishida :
インドシアニングリーンを用いたイオン液体の腸管吸収促進効果の検討,
日本薬剤学会第35年会, May 2020.
8. Maichi Hama, Hidenori Andou, Taro Shimizu, Yu Ishima and Tatsuhiro Ishida :
アルブミン結合型パクリタキセル製剤であるAbraxane®の新たな腫瘍移行機序の発見,
日本薬剤学会第35年会, May 2020.
9. Atsuya Maruyama, Hidenori Andou, 三輪 泰司, 濱本 英利, Taro Shimizu, Yu Ishima and Tatsuhiro Ishida :
イオン液体によるインドシアニングリーンの経口吸収性改善の検討,
日本薬学会第140年会, Mar. 2020.
10. Yoshino Kawaguchi, Mizuki Awata, Yuna Shimazaki, Chihiro Yoshioka, Taro Shimizu, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
細胞ワクチン療法への利用に適したB細胞サブセットの同定に関する検討,
日本薬学会第140年会, Mar. 2020.
11. Maichi Hama, Yu Ishima, Hidenori Andou, Taro Shimizu and Tatsuhiro Ishida :
アルブミン結合型パクリタキセル製剤であるAbraxane®の新たな腫瘍移行機序の発見,
日本薬学会第140年会, Mar. 2020.
12. Maki Sakai, Mayumi Ikeda, Hidenori Andou, Taro Shimizu, Yu Ishima and Tatsuhiro Ishida :
糖尿病患者血清におけるサルフェン硫黄の変動,
日本薬学会第140年会, Mar. 2020.
13. Hiroki Osafune, Mayumi Ikeda, Maki Sakai, Hidenori Andou, Taro Shimizu, Yu Ishima and Tatsuhiro Ishida :
ヒト唾液α-amylase活性に及ぼすサルフェン硫黄の影響,
日本薬学会第140年会, Mar. 2020.
14. Nanami Tasaka, Mayumi Ikeda, Taro Shimizu, Hidenori Andou, Keiichiro Okuhira, Yu Ishima and Tatsuhiro Ishida :
毛髪キューティクルに存在するポリスルフィドの発見とイオウ供給による毛髪損傷抑制効果の検討,
日本薬学会第140年会, Mar. 2020.
15. Shunsuke Akagi, Hidenori Andou, 松島 得雄, 草野 貴友 and Tatsuhiro Ishida :
新規セルロースナノファイバーゲルを用いた3次元培養法の開発,
第19回日本再生医療学会総会, Mar. 2020.
16. Chika Sakamoto, Taro Shimizu, Hidenori Andou, Yu Ishima, 小林 勝則, 石橋 賢樹, 三輪 泰司, 濱本 英利 and Tatsuhiro Ishida :
siRNA含有イオン液体製剤の経皮送達による乾癬治療,
第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Nov. 2019.
17. Hiro Ueda, Haruka Takata, Taro Shimizu, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
全身性エリテマトーデス病態時の脾臓免疫細胞によるマイクロパーティクルの取り込み変化の検討,
第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Nov. 2019.
18. Shunsuke Akagi, Hidenori Andou, 田島 健次, 松島 得雄, 草野 貴友 and Tatsuhiro Ishida :
物理化学的性質の異なるナノフィブリル化バクテリアセルロース(NFBC)を用いたPTX製剤の開発とがん治療評価,
第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Nov. 2019.
19. Shunsuke Akagi, Hidenori Andou, 田島 健次, 松島 得雄, 草野 貴友 and Tatsuhiro Ishida :
両親媒性ナノフィブリル化バクテリアセルロース(Fibnano)の放出制御型がん治療製剤への応用,
セルロース学会第26回年次大会, Jul. 2019.
20. Hidenori Andou :
ナノフィブリル化バクテリアセルロースのがん治療への応用,
産業技術総合研究所ナノセルロースフォーラム第15回セミナー, Jul. 2019.
21. Hiro Ueda, Haruka Takata, Taro Shimizu, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
マイクロパーティクルによる抗体産生誘導は全身性エリテマトーデスの症状進行に関与する,
第35回日本DDS学会学術集会, Jul. 2019.
22. Yuna Shimazaki, Hidenori Andou, Taro Shimizu, Yu Ishima and Tatsuhiro Ishida :
脾臓への抗原デリバリー技術を利用した新規抗体産生技術の開発,
第35回日本DDS学会学術集会, Jul. 2019.
23. Nanami Tasaka, Mayumi Ikeda, Taro Shimizu, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
毛髪ケラチン中に存在するポリスルフィドの酸化ストレス応答,
第72回日本酸化ストレス学会学術集会, Jun. 2019.
24. Arata Inoue, Yu Ishima, Mayumi Ikeda, Taro Shimizu, Hidenori Andou and Tatsuhiro Ishida :
細胞培養系における血清アルブミン結合sulfane sulfurの役割,
第19回日本NO学会学術集会, Jun. 2019.
25. Mayumi Ikeda, Yu Ishima, Maki Sakai, Taro Shimizu, Hidenori Andou, 渡邊 博志, 丸山 徹, 小田切 優樹 and Tatsuhiro Ishida :
ヒト血清アルブミンに存在するポリスルフィドによるユニークな酸化ストレス応答,
第19回日本NO学会学術集会, Jun. 2019.
26. Shota Fujimoto, Naoki Muguruma, Michiyasu Nakao, Hidenori Andou, Yoshihiko Miyamoto, Koichi Okamoto, Yasushi Sato, Tatsuhiro Ishida, Shigeki Sano and Tetsuji Takayama :
新規蛍光プローブIndocyanine green (ICG) 標識Dasatinibを用いた消化管間質腫瘍 (GIST) の近赤外蛍光 イメージング.,
第14回日本分子イメージング学会総会・学術集会, May 2019.
27. Shunsuke Akagi, Hidenori Andou, 田島 健次, 松島 得雄, 草野 貴友 and Tatsuhiro Ishida :
両親媒性ナノフィブリル化バクテリアセルロースを基剤とした放出制御型Paclitaxel製剤の開発,
日本薬剤学会第34年会, May 2019.
28. Mayumi Ikeda, Yu Ishima, Taro Shimizu, Hidenori Andou, Keiichiro Okuhira, 渡邊 博志, 丸山 徹, 小田切 優樹 and Tatsuhiro Ishida :
血清アルブミンの酸化ストレス応答を模倣した新規抗酸化剤の設計,
日本薬剤学会第34年会, May 2019.
29. Maho Tagami, Ai Ikeda, Hidenori Andou, 江島 清, 和田 洋巳 and Tatsuhiro Ishida :
腫瘍内微小環境の改善によるDDS製剤の治療効果増強,
日本薬学会第139年会, Mar. 2019.
30. Hidenori Andou :
尿アルカリ化を指標とした腫瘍内環境の改善,
第2回徳島大学統合的がん創薬研究クラスター合同ミーティング, Feb. 2019.
31. Maho Tagami, Hidenori Andou, Li Shyh-Dar and Tatsuhiro Ishida :
Continuous treatment with immune modulator can uniformize the effect of anti-tumor immunity,
第47回日本免疫学会学術集会, Dec. 2018.
32. Yuna Shimazaki, Taro Shimizu, Hidenori Andou and Tatsuhiro Ishida :
Expansion of the delivering technique of PEGylated liposomes to marginal zone B cells for immunization with peptide antigen,
第47回日本免疫学会学術集会, Dec. 2018.
33. Maki Sakai, Mayumi Ikeda, 今福 匡司, Hidenori Andou, Taro Shimizu, Yu Ishima, 丸山 徹 and Tatsuhiro Ishida :
糖尿病患者における血清中サルフェン硫黄と抗酸化能の評価,
第57回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Nov. 2018.
34. Hiroki Osafune, Mayumi Ikeda, Maki Sakai, Taro Shimizu, Hidenori Andou, Yu Ishima and Tatsuhiro Ishida :
生体液に含まれる活性イオウ分子種の検出,
第57回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Nov. 2018.
35. Ai Ikeda, Hidenori Andou, 江島 清, 和田 洋巳 and Tatsuhiro Ishida :
腫瘍内微小環境の改善にともなうDoxilの抗腫瘍効果増強,
第57回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Nov. 2018.
36. Hidenori Andou, Takashi Mochizuki, Kenji Fujita, Kenji Tajima, Tokuo Matsushima, Takatomo Kusano and Tatsuhiro Ishida :
Advanced application of nano-fibrillated bacterial cellulose (Fibnano®) to anti-cancer therapy,
第67回高分子討論会, Sep. 2018.
37. Yu Ishima, Ryo Kinoshita, Mayumi Ikeda, Hidenori Andou, Taro Shimizu, 小田切 優樹, 丸山 徹 and Tatsuhiro Ishida :
ガス状リガンドと相互作用するヒト血清アルブミンの臨床応用,
第1回超分子薬剤学FGシンポジウム, Sep. 2018.
38. Hidenori Andou, Takashi Mochizuki, Kenji Fujita, 田島 健次, 松島 得雄, 草野 貴友 and Tatsuhiro Ishida :
ナノフィブリル化バクテリアセルロース(Fibnano)を用いた新規パクリタキセル製剤の開発とがん治療への展開,
セルロース学会第25回年次大会, Jul. 2018.
39. Rie Matsuoka, Hidenori Andou and Tatsuhiro Ishida :
胃がん腹膜播種モデルにおいて腹腔内投与したカチオン性リポソームは腫瘍に選択的に集積する,
第34回日本DDS学会学術集会, Jun. 2018.
40. Ai Ikeda, Ryo Kinoshita, Hidenori Andou, 江島 清, 和田 洋巳 and Tatsuhiro Ishida :
がん細胞の代謝特異性を利用したドキソルビシンのがん細胞内送達法の開発,
第34回日本DDS学会学術集会, Jun. 2018.
41. Takashi Mochizuki, Hidenori Andou, Kenji Fujita, 田島 健次, Yu Ishima and Tatsuhiro Ishida :
ナノファイバーバイオセルロースを用いた新規パクリタキセル製剤の開発,
日本薬学会第138年会, Mar. 2018.
42. Tatsuhiro Ishida and Hidenori Andou :
新規RNAi薬剤体腔内投与による難治がん治療法の開発,
遺伝子・デリバリー研究会第17回夏期セミナー, Sep. 2017.
43. Rie Matsuoka, Hidenori Andou and Tatsuhiro Ishida :
腹腔内投与カチオン性リポソームの動態評価と胃がん腹膜播種治療における有用性に関する検討,
第26回DDSカンファランス, Sep. 2017.
44. Takashi Mochizuki, Hidenori Andou, Kenji Fujita, 田島 健次 and Tatsuhiro Ishida :
胃がん腹膜播種治療におけるナノファイバーバイオセルロースの応用に関する検討,
第33回日本DDS学会学術集会, Jul. 2017.
45. Noriaki Minakawa, Noriko Saito-Tarashima, Tomoki Takahashi, Seigi Yamamoto, Nozomi Kinjoh, Hidenori Andou, Tatsuhiro Ishida and Kentaro Kogure :
化学修飾DNAを利用したRNA創薬,
第33回日本DDS学会学術集会, Jul. 2017.
46. Emam Emam Abdallah Sherif, Hidenori Andou and Tatsuhiro Ishida :
A novel strategy to increase the yield of exosomes,
日本薬剤学会第32年会, May 2017.
47. Shota Fujimoto, Naoki Muguruma, Yoshihiko Miyamoto, Michiyasu Nakao, Shigeki Sano, Hidenori Andou, Tatsuhiro Ishida and Tetsuji Takayama :
KIT分子を標的としたGISTの分子イメージング,
第103回日本消化器病学会総会, Apr. 2017.
48. Takashi Mochizuki, Hidenori Andou, Kenji Fujita, 田島 健次 and Tatsuhiro Ishida :
ナノファイバーバイオセルロースの腹腔内がん化学療法への応用に関する検討,
日本薬学会第137年会, Mar. 2017.
49. Rie Matsuoka, Hidenori Andou and Tatsuhiro Ishida :
胃がん腹膜播種治療における腹腔内投与カチオン性リポソームの有用性に関する検討,
第55回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会, Nov. 2016.
50. Shinya Kobayashi, Hidenori Andou, Emam Emam Abdallah Sherif, Tatsuhiro Ishida and Kazuyoshi Kawazoe :
Doxorubicin投与による血清中Exosome分泌変化に関する検討,
第55回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会, Nov. 2016.
51. Rie Matsuoka, Hidenori Andou and Tatsuhiro Ishida :
新規胃がん腹膜播種治療開発のためのカチオン性リポソーム腹腔内投与の有用性探索,
ナノライフサイエンス・オープンセミナー2016, Sep. 2016.
52. 柏木 美咲, 西田 健太朗, 柴 俊輔, 室木 究, 大石 晃弘, Yusuke Doi, Hidenori Andou, Tatsuhiro Ishida and 長澤 一樹 :
オキサリプラチン封入PEG修飾リポソーム製剤投与ラットの後肢皮膚組織における白金蓄積及び手足症候群様症状の評価,
ナノライフサイエンス・オープンセミナー2016, Sep. 2016.
53. Hidenori Andou, Masao Tanaka and Tatsuhiro Ishida :
大型放射光施設(SPring-8)における蛍光X線分析法を用いたオキサリプラチン腫瘍内分布の分析,
第25回DDSカンファランス, Sep. 2016.
54. Hidenori Andou, Lila Selim Ahmed Ali Abu Amr, Chihiro Katoh, 福島 正和, 黄 政龍, 和田 洋巳 and Tatsuhiro Ishida :
核酸複合体(DFP-10825)の胸腔内直接投与を介した悪性胸膜中皮腫治療,
第32回日本DDS学会学術集会, Jul. 2016.
55. Emam Emam Abdallah Sherif, Hidenori Andou, Lila Selim Ahmed Ali Abu Amr, M.A. Mahmoud, G.S. Fakhr-eldin and Tatsuhiro Ishida :
Interaction of cancer cells with liposomes; the extent of exsosome release,
第32回日本DDS学会学術集会, Jun. 2016.
56. Rie Matsuoka, Hidenori Andou, 前田 典之 and Tatsuhiro Ishida :
胃がん腹膜播種治療のためのDDSキャリア腹腔内投与後の動態検討,
第32回日本DDS学会学術集会, Jun. 2016.
57. Nozomi Kinjoh, Hidenori Andou, Noriko Saito-Tarashima, Noriaki Minakawa and Tatsuhiro Ishida :
悪性胸膜中皮腫治療における新規shRNA発現化学修飾核酸の有用性の検討,
日本薬剤学会第31年会, May 2016.
58. Hidenori Andou, Sakiko Kobayashi, Lila Selim Ahmed Ali Abu Amr, 川添 和義 and Tatsuhiro Ishida :
ペメトレキセド封入カチオン性リポソームの胸腔内直接投与を介した悪性胸膜中皮腫治療,
日本薬剤学会第31年会, May 2016.
59. Nozomi Kinjoh, Hidenori Andou, Noriko Saito-Tarashima, Noriaki Minakawa and Tatsuhiro Ishida :
Intelligent shRNA expression deviceのin vitro, in vivoにおける有用性評価,
日本薬学会第136年会, Mar. 2016.
60. Takashi Mochizuki, Hidenori Andou and Tatsuhiro Ishida :
Doxil®及びオキサリプラチン封入リポソームの腹腔内投与の有用性に関する検討,
ナノライフサイエンス・オープンセミナー2015, Feb. 2016.
61. Nozomi Kinjoh, Hidenori Andou, Noriko Saito-Tarashima, Noriaki Minakawa and Tatsuhiro Ishida :
Intelligent RNA expression devise(iRed)による標的遺伝子抑制に関する検討,
第37回生体膜と薬物の相互作用シンポジウム, Nov. 2015.
62. Takashi Mochizuki, Hidenori Andou and Tatsuhiro Ishida :
抗がん剤徐放性製剤の腹腔内投与の有用性に関する検討,
第54回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Nov. 2015.
63. Nami Watanabe, Hidenori Andou and Tatsuhiro Ishida :
胃がん腹膜播種モデルにおけるオキサリプラチン封入リポソーム静脈内投与による腫瘍増殖抑制効果,
第31回日本DDS学会学術集会, Jul. 2015.
64. Nozomi Kinjoh, Hidenori Andou, Noriko Saito-Tarashima, Noriaki Minakawa and Tatsuhiro Ishida :
新規RNAi分子発現核酸デバイスのin vitro, in vivo有用性評価,
第31回日本DDS学会学術集会, Jul. 2015.
65. Chihiro Katoh, Lila Selim Ahmed Ali Abu Amr, Hidenori Andou and Tatsuhiro Ishida :
悪性胸膜中皮腫治療に向けたリポプレックスの胸腔内投与とその動態,
日本薬剤学会第30年会, May 2015.
66. Nami Watanabe, Hidenori Andou and Tatsuhiro Ishida :
胃がん腹膜播種動物モデルにおけるオキサリプラチン封入リポソームの治療効果に関する検討,
日本膜学会第37年会, May 2015.
67. Nozomi Kinjoh, Hidenori Andou, Noriko Saito-Tarashima, Noriaki Minakawa and Tatsuhiro Ishida :
新規RNAi分子発現核酸デバイスを用いた標的遺伝子発現抑制効果,
日本膜学会第37年会, May 2015.
68. Nozomi Kinjoh, Hidenori Andou, Noriko Saito-Tarashima, Noriaki Minakawa and Tatsuhiro Ishida :
胸腔内がん治療を目指した新規核酸デバイスの有用性評価,
遺伝子・デリバリー研究会第15回シンポジウム, May 2015.
69. Noriko Saito-Tarashima, 小島 孝光, Nozomi Kinjoh, Kazuhiro Furukawa, Hidenori Andou, Tatsuhiro Ishida and Noriaki Minakawa :
New strategy for suppression of gene expresstion using intelligent RNA expressing device (iRed),
日本化学会第95春季年会, Mar. 2015.
70. Noriko Saito-Tarashima, 小島 孝光, Nozomi Kinjoh, Kazuhiro Furukawa, Hidenori Andou, Tatsuhiro Ishida and Noriaki Minakawa :
Intelligent RNA expressing device (iRed)を利用した核酸創薬の新手法,
第32回メディシナルケミストリーシンポジウム, Nov. 2014.
71. Chihiro Katoh, Lila Selim Ahmed Ali Abu Amr, Hidenori Andou, Tatsuhiro Ishida and Hiroshi Kiwada :
悪性胸膜中皮腫治療のための核酸搭載カチオニックリポソームの胸腔内投与とその動態評価,
第36回生体膜と薬物の相互作用シンポジウム, Nov. 2014.
72. Nami Watanabe, Hidenori Andou and Tatsuhiro Ishida :
胃がん腹膜播種に対するナノキャリアを用いた新規投与経路の検討,
第53回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Nov. 2014.
73. Nozomi Kinjoh, Hidenori Andou, Noriko Saito-Tarashima, Noriaki Minakawa and Tatsuhiro Ishida :
Intelligent RNA expressing devise(iRed)の細胞内導入による標的遺伝子抑制,
第53回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Nov. 2014.
74. Nami Watanabe, Hidenori Andou and Tatsuhiro Ishida :
腹水を伴う腹膜播種における新規静注型治療法の確立,
ナノライフサイエンス・オープンセミナー2014, Aug. 2014.
75. Nozomi Kinjoh, Hidenori Andou, Noriko Saito-Tarashima, Noriaki Minakawa and Tatsuhiro Ishida :
Intelligent RNA expressing devise(iRed)のin vitroにおける標的遺伝子抑制に関する検討,
ナノライフサイエンス・オープンセミナー2014, Aug. 2014.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • Enhanced absorption drug delivery system by ionic liquid (Project/Area Number: 20K21898 )
  • PEG修飾タンパクによるアナフィラキシー誘導機構の解明とその制御に関する研究 (Project/Area Number: 19KK0279 )
  • 尿アルカリ化剤による抗がん剤治療効果の増強と効果予測 (Project/Area Number: 19K16415 )
  • Efficient anticancer drug delivery using a network structure of nanocellulose with a super high aspect ratio (Project/Area Number: 19H02549 )
  • Effects of anti-cancer drugs on secretion of tumor-related exosomes and its application for cancer treatment (Project/Area Number: 16K18861 )
  • Study of immunological response to nucleic acid delivery system (Project/Area Number: 15H04639 )
  • Development of novel cancer therapy via direct injection of DDS therapeutics into body cavity (Project/Area Number: 26893174 )
  • Search by Researcher Number (00735524)