徳島大学 / 教育研究者総覧 --- 森博康

個人のホームページ

https://researchmap.jp/morihiroyasu1720 (researchmap)

専門分野

○	ライフサイエンス (Life sciences) [栄養学、健康科学 (Nutrition and health science)]
○	ライフサイエンス (Life sciences) [食品科学 (Food sciences)]
○	ライフサイエンス (Life sciences) [リハビリテーション科学 (Rehabilitation science)]
○	ライフサイエンス (Life sciences) [代謝、内分泌学 (Metabolism and endocrinology)]

研究テーマ

著書・論文

学術論文(審査論文):

1.	Hiroyasu Mori, Satoshi Taniguchi, Yuu Tamaki, Motoyuki Tamaki, Yuko Akehi, Akio Kuroda and Munehide Matsuhisa : Telenutrition Education Is Effective for Glycemic Management in People with Type 2 Diabetes Mellitus: A Non-Inferiority Randomized Controlled Trial in Japan, Nutrients, Vol.16, No.2, 268, 2024. (要約) This study examined the non-inferior efficacy of telenutrition education compared with face-to-face nutrition education in managing glycemic control in people with type 2 diabetes mellitus (T2DM). Participants had T2DM and a glycated hemoglobin (HbA1c) ranged 6.5-9.5%. Thirty participants were randomly assigned to either the telenutrition or face-to-face nutrition education group. During the 32-week intervention period, the participants received four sessions on nutrition education from a registered dietitian at the hospital. The telenutrition group received remote education via a videoconferencing platform. Face-to-face nutrition education was conducted using paper-based instructions. The main outcome measure was the non-inferiority of HbA1c levels in the telenutrition group compared to the face-to-face nutrition group. The non-inferiority of telenutrition education was considered valid if the intergroup difference in the mean values of the change in HbA1c had a bilateral 95% confidence interval (CI) upper limit below 0.40%. The intergroup difference in the mean HbA1c change from baseline to the fourth nutrition education session was -0.11 (95% CI -0.54-0.32) for both groups. The upper limit of the bilateral 95% CI was 0.32%, which was below the 0.40% non-inferiority margin (non-inferiority test; = 0.011). Telenutrition education was not inferior to face-to-face nutrition education for glycemic management in people with T2DM. (キーワード) Humans / Diabetes Mellitus, Type 2 / Educational Status / Glycated Hemoglobin / Health Education / Japan (徳島大学機関リポジトリ) ● Metadata: 119489 (出版サイトへのリンク) ● Publication site (DOI): 10.3390/nu16020268 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38257162 ● Search Scopus @ Elsevier (PMID): 38257162 ● Search Scopus @ Elsevier (DOI): 10.3390/nu16020268 (徳島大学機関リポジトリ: 119489, DOI: 10.3390/nu16020268, PubMed: 38257162)
2.	Saya Yasui, Yousuke Kaneko, Hiroki Yamagami, Minae Hosoki, Taiki Hori, Akihiro Tani, Tomoyo Hara, Kiyoe Kurahashi, Takeshi Harada, Shingen Nakamura, Toshiki Otoda, Tomoyuki Yuasa, Hiroyasu Mori, Akio Kuroda, Itsuro Endo, Munehide Matsuhisa, Takeshi Soeki and Ken-ichi Aihara : Dehydroepiandrosterone Sulfate, an Adrenal Androgen, Is Inversely Associated with Prevalence of Dynapenia in Male Individuals with Type 2 Diabetes., Metabolites, Vol.13, No.11, 1129, 2023. (要約) Dehydroepiandrosterone sulfate (DHEAS) is thought to be associated with life expectancy and anti-aging. Although skeletal muscle disorders are often found in diabetic people, the clinical significance of DHEAS in skeletal muscle remains unclear. Therefore, we aimed to determine whether DHEAS is associated with the development of skeletal muscle disorders in individuals with type 2 diabetes (T2D). A cross-sectional study was conducted in 361 individuals with T2D. Serum DHEAS levels, skeletal muscle mass index (SMI), handgrip strength (HS), and gait speed (GS) were measured in the participants. Pre-sarcopenia, sarcopenia, and dynapenia were defined according to the definitions of the AWGS 2019 criteria. DHEAS level was positively associated with HS but not with SMI or GS after adjustment of confounding factors. Multiple logistic regression analyses in total subjects showed that DHEAS level had an inverse association with the prevalence of dynapenia but not with the prevalence of pre-sarcopenia or sarcopenia. Furthermore, a significant association between DHEAS level and dynapenia was found in males but not in females. ROC curve analysis indicated that cutoff values of serum DHEAS for risk of dynapenia in males was 92.0 μg/dL. Therefore, in male individuals with T2D who have low serum levels of DHEAS, adequate exercise might be needed to prevent dynapenia. (徳島大学機関リポジトリ) ● Metadata: 119107 (出版サイトへのリンク) ● Publication site (DOI): 10.3390/metabo13111129 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37999225 ● CiNii @ 国立情報学研究所 (CRID): 1870583643033891840 ● Summary page in Scopus @ Elsevier: 2-s2.0-85178271509 (徳島大学機関リポジトリ: 119107, DOI: 10.3390/metabo13111129, PubMed: 37999225, CiNii: 1870583643033891840, Elsevier: Scopus)
3.	森博康, 谷口諭, 玉木悠, 野村友美, 鈴木麗子, 黒田暁生, 明比祐子, 倉橋清衛, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 白神敦久, 田蒔基行, 天満仁, 長島伸光, 比木武, 松久宗英 : 2型糖尿病患者のPersonal Health Recordを用いたセルフモニタリングに自動支援メッセージが与える効果:探索的ランダム化比較試験, 日本糖尿病インフォマティクス学会誌, Vol.22, No.2, 7-18, 2023年.
4.	川上歩花, 板東美香, 髙士友恵, 杉内美月, Mizusa Hyodo, 三島優奈, Masashi Kuroda, 森博康, 黒田暁生, 湯本浩通, 松久宗英, 阪上浩, 堤理恵 : Umami taste sensitivity is associated with food intake and oral environment in subjects with diabetes, The Journal of Medical Investigation : JMI, Vol.70, No.1.2, 241-250, 2023年. (要約) Dysgeusia is a serious problem in patients with diabetes because it often leads to overeating, which is associated with disease progression. This study aimed to investigate the association between taste sensitivity, eating habits, and the oral environment. In this cross-sectional study of 75 subjects with diabetes, gustatory function was assessed using the whole-mouth method, and lingual taste receptor gene expression was measured by real-time PCR. Food intake was evaluated using a food frequency questionnaire based on food groups. The oral environment was assessed using xerostomia and periodontal comprehensive examination. In total, 45.3%, 28.0%, and 18.7% of subjects showed lower umami taste sensitivity, low sweet taste sensitivity, and low salt taste sensitivity, respectively. Lower umami sensitivity correlated with lower estimated glomerular filtration rate and higher energy-source food intake. Subjects with diabetes with higher plaque control record showed significantly higher T1R3 gene expression than those with lower plaque control record. Reduced umami taste sensitivity is associated with decreased renal function and high energy food intake in diabetes. Subjects with diabetes with higher plaque control record showed significantly higher T1R3 gene expression, suggesting that the oral environment affects taste gene expression. J. Med. Invest. 70 : 241-250, February, 2023. (キーワード) Humans / Taste / Cross-Sectional Studies / Taste Perception / Diabetes Mellitus / Eating (徳島大学機関リポジトリ) ● Metadata: 118208 (出版サイトへのリンク) ● Publication site (DOI): 10.2152/jmi.70.241 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37164729 ● Summary page in Scopus @ Elsevier: 2-s2.0-85158866092 (徳島大学機関リポジトリ: 118208, DOI: 10.2152/jmi.70.241, PubMed: 37164729, Elsevier: Scopus)
5.	Tomoharu Kawano, Motohiro Aiba, Masashi Ishizu, Hiroyasu Mori, Munehide Matsuhisa, Seiichi Hashida, Tracey Colpitts and Toshihiro Watanabe : Molecular composition of adiponectin in urine is a useful biomarker for detecting early stage of diabetic kidney disease., The Journal of Medical Investigation : JMI, Vol.70, No.3.4, 464-470, 2023. (要約) We previously developed two immune complex transfer enzyme immunoassays (ICT-EIA) to measure total adiponectin (T-AN) and high molecular weight adiponectin (H-AN) in urine and have verified their usefulness as biomarkers for diabetic kidney disease. In this study, we developed T-AN and H-AN assays using the sandwich EIA (Sand-EIA). The reactivities of Sand-EIAs were compared with ICT-EIAs by measuring size exclusion chromatography (SEC) fractions of urine and adiponectin standard. As a result, ICT-EIAs showed higher macromolecular specificity. We then analyzed the molecular profile of adiponectin in the urine of 5 patients with different eGFR stages by measuring SEC fractions of urine. The results showed that smaller adiponectin correlated relatively well with eGFR stage. Finally, because SEC is time-consuming, we investigated that the ratio of T-ANs by Sand-EIA and ICT-EIA could be a good indicator of the monomer adiponectin. The ratio was evaluated using 77 urine samples from patients with diabetes and showed a significant decrease at an earlier stage compared with other biomarkers. In conclusion, we demonstrated a new index to estimate monomer adiponectin in urine by using Sand-EIA and ICT-EIA, and urinary monomer adiponectin can be a good early indicator of deterioration of renal function in diabetic patients. J. Med. Invest. 70 : 464-470, August, 2023. (キーワード) Humans / Diabetic Nephropathies / Adiponectin / Sensitivity and Specificity / Sand / Biomarkers / Diabetes Mellitus (徳島大学機関リポジトリ) ● Metadata: 118797 (出版サイトへのリンク) ● Publication site (DOI): 10.2152/jmi.70.464 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37940533 ● Search Scopus @ Elsevier (PMID): 37940533 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.70.464 (徳島大学機関リポジトリ: 118797, DOI: 10.2152/jmi.70.464, PubMed: 37940533)
6.	Hiroyasu Mori, Yasunobu Tokuda, Eriko Yoshida, Kenji Uchida and Munehide Matsuhisa : Chronic Intake of a Meal Including Alaska Pollack Protein Increases Skeletal Muscle Mass and Strength in Healthy Older Women: A Double-Blind Randomized Controlled Trial, The Journal of Nutrition, Vol.152, No.12, 2761-2770, 2022. (要約) In animal studies, a meal containing Alaska pollack protein (APP) induces fast-twitch muscle hypertrophy. To our knowledge, no interventional studies have examined the benefits of APP intake on muscle mass and muscle weakness and the prevention of sarcopenia in older individuals. We evaluated the effects of APP intake on skeletal muscle mass, muscle strength, and physical performance among healthy community-dwelling older Japanese women. In this double-blind randomized controlled trial, healthy women 65 y old were allocated to an APP or whey protein control (CON) group. Participants ingested test protein meals (5.0-5.1 g protein/serving) daily for 24 wk. Between-group differences in the change of skeletal muscle mass index (SMI) as the primary outcome and muscle strength as a secondary outcome were tested using multifrequency BIA and a handheld dynamometer, respectively, at baseline, and 4, 12, and 24 wk. The mean changes in the measured primary and secondary outcome variables from baseline to 4, 12, and 24 wk were compared using unpaired t tests. There were no between-group differences in nutritional status, food intake, or total energy and protein intakes at baseline, 12 wk, or 24 wk. The change in SMI was 0.12 kg/m2 (95% CI: 0.01, 0.23 kg/m2) and 0.11 kg/m2 (95% CI: 0.03, 0.19 kg/m2) greater in the APP group than in the CON group at 12 wk and 24 wk (P 0.03) and knee extension strength was 0.07 Nm/kg BW (95% CI: 0.02, 0.12 Nm/kg BW) and 0.05 Nm/kg BW (95% CI: 0.00, 0.09 Nm/kg BW) higher in the APP group than in the CON group at these times (P 0.015), respectively. The groups did not differ at 4 wk. Daily intake of a meal containing APP compared with whey protein increases skeletal muscle mass and lower-extremity muscle strength in healthy older women, suggesting that an APP-containing meal may be useful in the prevention of sarcopenia in this group.This trial was registered at as UMIN000035718. (キーワード) Animals / Female / Sarcopenia / Whey Proteins / Muscle, Skeletal / Alaska / Muscle Strength / Meals / Double-Blind Method / Dietary Supplements / Dietary Proteins (出版サイトへのリンク) ● Publication site (DOI): 10.1093/jn/nxac219 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36138493 ● Search Scopus @ Elsevier (PMID): 36138493 ● Search Scopus @ Elsevier (DOI): 10.1093/jn/nxac219 (DOI: 10.1093/jn/nxac219, PubMed: 36138493)
7.	Hiroyasu Mori and Tokuda Yasunobu : De-Training Effects Following Leucine-Enriched Whey Protein Supplementation and Resistance Training in Older Adults with Sarcopenia: A Randomized Controlled Trial with 24 Weeks of Follow-Up, The Journal of Nutrition, Health & Aging, Vol.26, No.11, 994-1002, 2022. (要約) This study aimed to evaluate the effectiveness of de-training after a combined intervention of leucine-enriched whey protein supplementation and resistance training on skeletal muscle mass and strength in older adults with sarcopenia. A randomized controlled trial. A community in Hyogo, Japan. The study included older adults aged ≥ 65 years who were screened for sarcopenia at the Care Center from, a community in Hyogo, Japan. The participants were randomly allocated to one of three groups: whey protein supplementation after resistance training (RT + PRO; n = 27), resistance training only (RT; n = 27), and whey protein supplementation only (PRO; n = 27). An intervention program was conducted over a period of 24 weeks. The program included RT and/or PRO supplementation twice a week for 24 weeks, followed by a de-training period for another 24 weeks. PRO supplementation included 11.0 g of protein and 2,300 mg of leucine. The total energy and protein intake amounts for the participants in all groups were controlled to achieve at least 30 kcal/kg ideal body weight (IBW)/day and 1.2 g/kg IBW/day, respectively, during the intervention and de-training periods. The primary outcomes, such as mean change of appendicular skeletal muscle mass index (ΔASMI), and secondary outcomes, such as handgrip strength (ΔHGS), were measured at baseline, the end of intervention, and at 12 and 24 weeks of de-training. Compared to baseline, ASMI and HGS increased significantly at the end of the intervention period in the RT+PRO group (ASMI and HGS, p < 0.01); however, there were no significant differences in ΔASMI and ΔHGS between each group. At 24 weeks of the de-training period, ΔASMI and ΔHGS were higher in the RT + PRO group than in the RT group (p < 0.05 and p < 0.01, respectively). We demonstrated that combined intervention of RT and PRO showed long-term maintenance in treating sarcopenia than RT only at 24 weeks after de-training. Therefore, PRO intake after RT may be useful in the treatment of sarcopenia in older adults. (キーワード) Humans / Aged / Resistance Training / Sarcopenia / Whey Proteins / Leucine / Hand Strength / Muscle Strength / Follow-Up Studies / Dietary Supplements (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s12603-022-1853-1 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36437767 ● Summary page in Scopus @ Elsevier: 2-s2.0-85140129868 (DOI: 10.1007/s12603-022-1853-1, PubMed: 36437767, Elsevier: Scopus)
8.	Asami Okada, Misuzu Yamada-Yamashita, Yukari Tominaga, Kyoka Jo, Hiroyasu Mori, Reiko Suzuki, Masashi Ishizu, Motoyuki Tamaki, Yuko Akehi, Yuichi Takashi, Daisuke Koga, Eisuke Shimokita, Fuminori Tanihara, Kiyoe Kurahashi, Sumiko Yoshida, Yukari Mitsui, Shiho Masuda, Itsuro Endo, Ken-ichi Aihara, Shoji Kagami, Masahiro Abe, Kevin Ferreri, Yoshio Fujitani, Munehide Matsuhisa and Akio Kuroda : Novel method utilizing bisulfite conversion with dual amplification-refractory mutation system polymerase chain reaction to detect circulating pancreatic β-cell cfDNA., Journal of Diabetes Investigation, Vol.13, No.7, 1140-1148, 2022. (要約) We developed a novel method for detecting unmethylated insulin DNA in circulation that can be performed using a conventional real-time PCR system. This method would be useful for analyzing dynamic profiles of β-cells in human disease such as type 1 diabetes. (徳島大学機関リポジトリ) ● Metadata: 117206 (出版サイトへのリンク) ● Publication site (DOI): 10.1111/jdi.13806 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35396829 ● Search Scopus @ Elsevier (PMID): 35396829 ● Search Scopus @ Elsevier (DOI): 10.1111/jdi.13806 (徳島大学機関リポジトリ: 117206, DOI: 10.1111/jdi.13806, PubMed: 35396829)
9.	Yukari Mitsui, Akio Kuroda, Masashi Ishizu, Hiroyasu Mori, Kiyoe Kurahashi, Takeshi Kondo, Sumiko Yoshida, Yuko Akehi, Ken-ichi Aihara, Itsuro Endo, Masahiro Abe and Munehide Matsuhisa : Basal insulin requirement in patients with type 1 diabetes depends on the age and body mass index., Journal of Diabetes Investigation, Vol.13, No.2, 292-298, 2022. (要約) T (徳島大学機関リポジトリ) ● Metadata: 116546 (出版サイトへのリンク) ● Publication site (DOI): 10.1111/jdi.13547 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33740836 ● Search Scopus @ Elsevier (PMID): 33740836 ● Search Scopus @ Elsevier (DOI): 10.1111/jdi.13547 (徳島大学機関リポジトリ: 116546, DOI: 10.1111/jdi.13547, PubMed: 33740836)
10.	Yasunobu Tokuda and Hiroyasu Mori : Essential Amino Acid and Tea Catechin Supplementation after Resistance Exercise Improves Skeletal Muscle Mass in Older Adults with Sarcopenia: An Open-Label, Pilot, Randomized Controlled Trial., Journal of the American Nutrition Association, 1-8, 2022. (要約) The mean adherence rate to exercise and supplementation intake over the 24-week intervention period was 86.8% in the RE + EAA + TCC group, 86.4% in the RE + EAA group, and 85.4% in the RE group. A significant group-by-time interaction was identified for SMM (p = 0.010). The pre- to post-intervention increase in SMM was significantly higher in the RE + EAA + TCC group than in the RE group (p = 0.010). (出版サイトへのリンク) ● Publication site (DOI): 10.1080/07315724.2022.2025546 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35512762 ● Search Scopus @ Elsevier (PMID): 35512762 ● Search Scopus @ Elsevier (DOI): 10.1080/07315724.2022.2025546 (DOI: 10.1080/07315724.2022.2025546, PubMed: 35512762)
11.	Kana Beppu, Ayuka Kawakami, Yuna Mishima, Rie Tsutsumi, Masashi Kuroda, Hiroyasu Mori, Akio Kuroda, Munehide Matsuhisa and Hiroshi Sakaue : Taste receptor gene expression is associated with decreased eGFR in patients with diabetes., The Journal of Medical Investigation : JMI, Vol.69, No.1.2, 120-126, 2022. (要約) Dysgeusia is not only associated with zinc deficiency but also with certain drugs or diseases, including diabetes and renal failure. It often lowers the patient's quality of life and hinders access to proper nutrition. The underlying mechanism is unclear and there is a lack of awareness among patients. Here, we focused on lingual taste receptor gene expression in diabetes and elucidated the relationship between taste receptor gene expression and renal function. Forty-seven patients with diabetes and 10 healthy subjects (control group) were enrolled. Lingual foliate papillae were scraped and the derived cDNA was quantified by real-time polymerase chain reaction. Dysgeusia was assessed using SALSAVE?. All statistical analyses were performed using JMP? software 13. The expression of T1R1 and T1R2 was significantly upregulated in type 2 diabetes patients as compared with that in healthy subjects (P<0.01) but did not change in type 1 diabetes patients. T1R3 expression positively correlated and Scnn1 expression negatively correlated with estimated glomerular filtration rate, suggesting that altered taste receptor gene expression could reflect impaired renal function. Thus, alterations in T1R3 and Scnn1 expression in diabetes correlated with renal function. Taste receptor gene expression dysregulation could indicate dysgeusia associated with impaired renal function in patients with diabetes. J. Med. Invest. 69 : 120-126, February, 2022. (キーワード) Diabetes Mellitus, Type 2 / Dysgeusia / Gene Expression / Humans / Quality of Life / Receptors, G-Protein-Coupled / Taste (徳島大学機関リポジトリ) ● Metadata: 117023 (出版サイトへのリンク) ● Publication site (DOI): 10.2152/jmi.69.120 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35466133 ● CiNii @ 国立情報学研究所 (CRID): 1390291932617710464 ● Summary page in Scopus @ Elsevier: 2-s2.0-85128801393 (徳島大学機関リポジトリ: 117023, DOI: 10.2152/jmi.69.120, PubMed: 35466133, CiNii: 1390291932617710464, Elsevier: Scopus)
12.	岡田朝美, 山田美鈴, 森博康, 明比祐子, 倉橋清衛, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 松久宗英, 黒田暁生 : 循環血中遊離 DNA を用いた膵β細胞傷害の新規検出法の確立, 四国医学雑誌, Vol.77, No.5,6, 249-254, 2021年. (要約) In people with type1 diabetes(T1D), biomarkers that can sensitively and quantitatively evaluate injury of pancreatic beta cell are required in order to predict the onset of the disease at an early stage and to provide interventions to prevent the progression of the disease. We developed a new method for quantifying pancreatic beta cell-derived insulin DNA in circulation that combines bisulfite conversion and Amplification Refractory Mutation System(ARMS)PCR, which can be performed using a conventional real-time PCR system. We applied this method to T1D patients and healthy adults, both could be detected in about 30% of cases. The results in healthy adults indicate that this method may have sensitivity to detect the turnover of pancreatic beta cells at physiological conditions. In post-onset T1D patients, there were many negatives because the amount of residual pancreatic beta cells was extremely small. However, in some cases with a short duration of the disease, pancreatic beta cell-derived insulin DNA was detected in negative correlation between the duration of the disease, that suggested the residual pancreatic beta cells continue to be slowly destroyed. It was demonstrated that the time course of pathophysiology in T1D could be understood using this method. (キーワード) インスリン (insulin) / DNA methylation / RT-PCR / Type1 diabetes / cell-free DNA (徳島大学機関リポジトリ) ● Metadata: 117138 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1520573657290659200 (徳島大学機関リポジトリ: 117138, CiNii: 1520573657290659200)
13.	松久宗英, 森博康, 谷口諭, 玉木悠, 黒田暁生 : 情報を活かし地域に沿った腎症重症化予防策「行政・医療機関の情報を活用したヒューマンネットワークによる糖尿病重症化」, 日本糖尿病情報学会誌 18: 43-49, 2021.8.31, Vol.18, 43-49, 2021年.
14.	Sonyun Hata, Hiroyasu Mori, Tetsuyuki Yasuda, Yoko Irie, Tsunehiko Yamamoto, Yutaka Umayahara, Kayoko Ryomoto, Kazutomi Yoshiuchi, Sumiko Yoshida, Iichiro Shimomura, Akio Kuroda and Munehide Matsuhisa : A low serum IGF-1 is correlated with sarcopenia in subjects with type 1 diabetes mellitus: Findings from a post-hoc analysis of the iDIAMOND study., Diabetes Research and Clinical Practice, Vol.179, 2021. (要約) The z-score of serum IGF-1 was significantly lower in the subjects with T1DM than that in those without diabetes (p < 0.001). Among subjects with T1DM, the z-score of serum IGF-1 was significantly lower in sarcopenic subjects than in non-sarcopenic subjects. The multivariable logistic regression analysis showed that the serum IGF-1 z-score was an independent determinant of sarcopenia and a low skeletal muscle mass index, but not low grip strength nor slow gait speed in subjects with T1DM. (キーワード) Cross-Sectional Studies / Diabetes Mellitus, Type 1 / Hand Strength / Humans / Insulin-Like Growth Factor I / Muscle, Skeletal / Sarcopenia (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.diabres.2021.108998 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34390761 ● Search Scopus @ Elsevier (PMID): 34390761 ● Search Scopus @ Elsevier (DOI): 10.1016/j.diabres.2021.108998 (DOI: 10.1016/j.diabres.2021.108998, PubMed: 34390761)
15.	Yasunobu Tokuda and Hiroyasu Mori : Effect of ingestion of essential amino acids and tea catechins after resistance exercise on the muscle mass, physical performance, and quality of life of healthy older people: A randomized controlled trial, Asia Pacific Journal of Clinical Nutrition, Vol.30, No.2, 213-223, 2021. (要約) We evaluated the effectiveness of a 24-week nutritional ingestion program involving essential amino acid (AA) and tea catechin (TC) intake after performing resistance exercise in increasing the skeletal muscle mass, physical performance, and quality of life of healthy older people. An open-label randomized controlled trial involving 84-healthy older individuals (age ≥65 years) without sarcopenia, diabetes, and kidney disease, was conducted. They were allocated to the exercise (n=28), exercise and essential AA ingestion (n=28), and exercise, essential AA, and TC ingestion groups (n=28). The participants underwent a 24-week program of resistance exercise (performed twice per week) along with essential AA and TC intake (3,000 and 540 mg, respectively). Six participants could not complete the intervention after randomization. After the 24-week intervention period, the exercise, essential AA, and TC ingestion groups showed an increase in the skeletal muscle mass index, one-legged balance test, and physical quality of life score (skeletal muscle mass index, p=0.004; one-legged balance test, p=0.045; physical quality of life, p=0.020). After the 24- week intervention period, the exercise and essential AA ingestion group showed an increase in the skeletal muscle mass index and physical quality of life score (skeletal muscle mass index, p=0.014; physical quality of life, p=0.041). However, the exercise group did not show an increase in the skeletal muscle mass index. These results suggested that resistance exercise, essential AA, and TC intake in healthy older people could improve physical performance. (出版サイトへのリンク) ● Publication site (DOI): 10.6133/apjcn.202106_30(2).0005 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34191423 ● Search Scopus @ Elsevier (PMID): 34191423 ● Search Scopus @ Elsevier (DOI): 10.6133/apjcn.202106_30(2).0005 (DOI: 10.6133/apjcn.202106_30(2).0005, PubMed: 34191423)
16.	徳田泰伸, 森博康 : レジスタンス運動後の乳清たんぱく質の摂取が高齢女性のサルコペニア治療とQOLに与える効果:無作為化比較試験, 体力科学, Vol.70, No.3, 207-218, 2021年. (要約) <p>To evaluate the effectiveness of a 24-week nutritional supplementation program involving whey protein intake after resistance exercise in treatment of sarcopenia and quality of life (QOL) among older women with sarcopenia, we carried out a pilot study, randomized controlled trial among elderly individuals with sarcopenia, aged 65-years or older, who were allocated to three groups: exercise and whey protein supplementation (Ex+Whey) group, exercise (Ex) group, and whey protein supplementation (Whey) group. Sarcopenia was defined using the Asian Working Group for sarcopenia 2014 criteria, as follows: low hand-grip strength (<18.0 kg) or slow gait speed (<0.8m/sec), and low skeletal muscle mass index (SMI, <5.7kg/m<sup>2</sup>). A 24-week program of resistance exercise, carried out twice per week, was combined with whey protein supplementation, involving 11.0 g of protein and 2,300 mg of leucine. After the 24-week intervention period, the Ex+Whey group (n=20) showed a decrease in sarcopenia, lower SMI, lower grip strength, and increase in physical QOL score (sarcopenia; p=0.004, SMI and grip strength; p=0.008, QOL; p=0.027). After the 24-week intervention period, the Whey group (n=20) showed a decrease in sarcopenia and lower SMI (all p=0.017). The Ex-group (n=19) did not show a decrease in sarcopenia, lower SMI, and lower grip strength. These results suggest that resistance exercise and whey protein intake in older women with sarcopenia, on the multiple outcome measures such as improves lower SMI, lower grip strength, and physical QOL. However, there were no between-group differences in the change from the pre- to the post-intervention period at 24 weeks in the lower SMI and lower grip strength. In this study, the intervention effect of Ex+Whey could not be clearly shown in the outcome measures.</p> (キーワード) sarcopenia / whey protein resistance exercise / physical function / quality of life (徳島大学機関リポジトリ) ● Metadata: 119141 (出版サイトへのリンク) ● Publication site (DOI): 10.7600/jspfsm.70.207 (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1390850954360416896 ● Search Scopus @ Elsevier (DOI): 10.7600/jspfsm.70.207 (徳島大学機関リポジトリ: 119141, DOI: 10.7600/jspfsm.70.207, CiNii: 1390850954360416896)
17.	Hiroyasu Mori, Akio Kuroda, Sumiko Yoshida, Tetsuyuki Yasuda, Yutaka Umayahara, Sayoko Shimizu, Kayoko Ryomoto, Kazutomi Yoshiuchi, Tsunehiko Yamamoto, Taka-Aki Matsuoka, Iichiro Shimomura and Munehide Matsuhisa : High prevalence and clinical impact of dynapenia and sarcopenia in Japanese patients with type 1 and type 2 diabetes: Findings from the Impact of Diabetes Mellitus on Dynapenia study., Journal of Diabetes Investigation, Vol.12, No.6, 1050-1059, 2021. (要約) Sarcopenia and dynapenia were more frequent in patients with type 1 diabetes and type 2 diabetes than in individuals without diabetes, which might contribute to their impaired quality of life and incidental falls. (徳島大学機関リポジトリ) ● Metadata: 116547 (出版サイトへのリンク) ● Publication site (DOI): 10.1111/jdi.13436 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33063949 ● Search Scopus @ Elsevier (PMID): 33063949 ● Search Scopus @ Elsevier (DOI): 10.1111/jdi.13436 (徳島大学機関リポジトリ: 116547, DOI: 10.1111/jdi.13436, PubMed: 33063949)
18.	Masashi Ishizu, Hiroyasu Mori, Mami Ohishi, Akio Kuroda, Y Akehi, Sumiko Yoshida, Ken-ichi Aihara, M Aiba, T Kawano, Seiichi Hashida and Munehide Matsuhisa : Urinary adiponectin excretion is an early predictive marker of the decline of the renal function in patients with diabetes mellitus., Journal of Diabetes and its Complications, Vol.35, No.4, 107848, 2021. (要約) Since diabetes-associated kidney complication changes from diabetic nephropathy to diabetic kidney disease (DKD), more suitable biomarkers than urinary albumin are required. It has been hypothesized that urinary adiponectin (u-ADPN) is associated with the progression of DKD. We therefore evaluated the effectiveness of u-ADPN in predicting the decline of the renal function in patients with diabetes prior to end-stage renal disease. An ultrasensitive immune complex transfer enzyme immunoassay (ICT-EIA) was used to measure total and high molecular weight (HMW) adiponectin separately. We evaluated the relationships between the creatinine-adjusted urinary total-ADPN and HMW-ADPN, albumin (UACR) and liver-type fatty acid binding protein (L-FABP) at baseline and the 2-year change of the estimated glomerular filtration rate (ΔeGFR). This 2-year prospective observational study included 201 patients with diabetes. These patients were divided into three groups according to their ΔeGFR: ≤-10 mL/min/1.73m, >-10 and ≤0 mL/min/1.73m, and >0 mL/min/1.73m. Jonckheere-Terpstra test showed that lower ΔeGFR was associated with higher u-HMW-ADPN (p = 0.045). In logistic regression analysis, u-HMW-ADPN was associated with ΔeGFR after adjusted age, sex, and basal eGFR. Urinary HMW-ADPN could predict a declining renal function in patients with diabetes. (徳島大学機関リポジトリ) ● Metadata: 115675 (出版サイトへのリンク) ● Publication site (DOI): 10.1016/j.jdiacomp.2021.107848 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33558151 ● Search Scopus @ Elsevier (PMID): 33558151 ● Search Scopus @ Elsevier (DOI): 10.1016/j.jdiacomp.2021.107848 (徳島大学機関リポジトリ: 115675, DOI: 10.1016/j.jdiacomp.2021.107848, PubMed: 33558151)
19.	Toshihiro Watanabe, Yuki Fujimoto, Aya Morimoto, Mai Nishiyama, Akinori Kawai, Seiki Okada, Motohiro Aiba, Tomoharu Kawano, Mina Kawahigashi, Masashi Ishizu, Hiroyasu Mori, Munehide Matsuhisa, Akiko Hata, Makoto Funaki and Seiichi Hashida : Development of fully automated and ultrasensitive assays for urinary adiponectin and their application as novel biomarkers for diabetic kidney disease., Scientific Reports, Vol.10, No.1, 15869, 2020. (要約) Glomerular filtration rate (GFR) and urinary albumin excretion rate (UAER) are used to diagnose and classify the severity of chronic kidney disease. Total adiponectin (T-AN) and high molecular weight adiponectin (H-AN) assays were developed using the fully automated immunoassay system, HI-1000 and their significance over conventional biomarkers were investigated. The T-AN and H-AN assays had high reproducibility, good linearity, and sufficient sensitivity to detect trace amounts of adiponectin in the urine. Urine samples after gel filtration were analyzed for the presence of different molecular isoforms. Low molecular weight (LMW) forms and monomers were the major components (93%) of adiponectin in the urine from a diabetic patient with normoalbuminuria. Urine from a microalbuminuria patient contained both high molecular weight (HMW) (11%) and middle molecular weight (MMW) (28%) adiponectin, although the LMW level was still high (52%). The amount of HMW (32%) and MMW (42%) were more abundant than that of LMW (24%) in a diabetic patient with macroalbuminuria. T-AN (r = - 0.43) and H-AN (r = - 0.38) levels showed higher correlation with estimated GFR (eGFR) than UAER (r = - 0.23). Urinary levels of both T-AN and H-AN negatively correlated with renal function in diabetic patients and they may serve as new biomarkers for diabetic kidney disease. (徳島大学機関リポジトリ) ● Metadata: 115617 (出版サイトへのリンク) ● Publication site (DOI): 10.1038/s41598-020-72494-6 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32985540 ● Search Scopus @ Elsevier (PMID): 32985540 ● Search Scopus @ Elsevier (DOI): 10.1038/s41598-020-72494-6 (徳島大学機関リポジトリ: 115617, DOI: 10.1038/s41598-020-72494-6, PubMed: 32985540)
20.	Hiroyasu Mori, Akio Kuroda and Munehide Matsuhisa : Clinical impact of sarcopenia and dynapenia on diabetes., Diabetology International, Vol.10, No.3, 183-187, 2019. (要約) Sarcopenia as a progressive and generalized skeletal muscle disorder that is associated with an increased likelihood of adverse outcomes, including falls, fractures, physical disability, and mortality. On the other hand, an age-related decline in muscle strength prior to the reduction of muscle mass, is proposed to be "dynapenia". Sarcopenia and dynapenia have recently been recognized as a diabetic complications in type 2 diabetes. We firstly indicated that sarcopenia was frequently observed in 16.6% of patients with type 1 diabetes aged even over 40 years. Additionally, we recently reported that the prevalence rate of dynapenia was higher than sarcopenia in patients with type 2 diabetes. Chronic hyperglycemia accelerates accumulation of advanced glycation end products (AGEs), which causes diabetic vascular complications through oxidative stress and chronic inflammation. We also demonstrated that skin autofluorescence (AF) as a marker of AGEs, was the independent determinant for skeletal muscle mass and strength in patients with type 2 diabetes and muscle strength in type 1 diabetes. Therefore, the early diagnosis of muscle weakness is essential for patients with diabetes and sustained good glycemic control with exercise and dietary intervention might be beneficial to prevent the progression of muscle weakness in these patients. (徳島大学機関リポジトリ) ● Metadata: 114038 (出版サイトへのリンク) ● Publication site (DOI): 10.1007/s13340-019-00400-1 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31275784 ● Summary page in Scopus @ Elsevier: 2-s2.0-85068062045 (徳島大学機関リポジトリ: 114038, DOI: 10.1007/s13340-019-00400-1, PubMed: 31275784, Elsevier: Scopus)
21.	Yuichi Takashi, Masashi Ishizu, Hiroyasu Mori, Kazuyuki Miyashita, Fumie Sakamoto, Naoto Katakami, Taka-Aki Matsuoka, Tetsuyuki Yasuda, Seiichi Hashida, Munehide Matsuhisa and Akio Kuroda : Circulating osteocalcin as a bone-derived hormone is inversely correlated with body fat in patients with type 1 diabetes., PLoS ONE, Vol.14, No.5, 2019. (要約) The objective of the present study was to investigate the correlations between serum undercarboxylated osteocalcin (ucOC) or osteocalcin (OC) concentrations and %body fat, serum adiponectin and free-testosterone concentration, muscle strength and dose of exogenous insulin in patients with type 1 diabetes. We recruited 73 Japanese young adult patients with childhood-onset type 1 diabetes. All participants were receiving insulin replacement therapy. The correlations between logarithmic serum ucOC or OC concentrations and each parameter were examined. Serum ucOC and OC concentrations were inversely correlated with %body fat (r = -0.319, P = 0.007; r = -0.321, P = 0.006, respectively). Furthermore, multiple linear regression analyses were performed to determine whether or not serum ucOC or OC concentrations were factors associated with %body fat. Serum ucOC and OC concentrations remained significant factors even after adjusting for gender, HbA1c, body weight-adjusted total daily dose of insulin and duration of diabetes (β = -0.260, P = 0.027; β = -0.254, P = 0.031, respectively). However, serum ucOC and OC concentrations were not correlated with serum adiponectin or free-testosterone concentrations, muscle strength or dose of exogenous insulin. In conclusion, our study demonstrates the inverse correlation between serum ucOC or OC concentrations and body fat in patients with type 1 diabetes. (徳島大学機関リポジトリ) ● Metadata: 114023 (出版サイトへのリンク) ● Publication site (DOI): 10.1371/journal.pone.0216416 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31050684 ● Search Scopus @ Elsevier (PMID): 31050684 ● Search Scopus @ Elsevier (DOI): 10.1371/journal.pone.0216416 (徳島大学機関リポジトリ: 114023, DOI: 10.1371/journal.pone.0216416, PubMed: 31050684)
22.	Hiroyasu Mori, Akio Kuroda, Masashi Ishizu, Mami Ohishi, Yuichi Takashi, Yinhua Otsuka, Satoshi Taniguchi, Motoyuki Tamaki, Kiyoe Kurahashi, Sumiko Yoshida, Itsuro Endo, Ken-ichi Aihara, Makoto Funaki, Yuko Akehi and Munehide Matsuhisa : Association of accumulated advanced glycation end-products with a high prevalence of sarcopenia and dynapenia in patients with type 2 diabetes., Journal of Diabetes Investigation, 2019. (要約) Advanced glycation end-products (AGEs), which are a major cause of diabetic vascular complications, accumulate in various tissues under chronic hyperglycemic conditions, as well as with aging in patients with diabetes. The loss of muscle mass and strength, so-called sarcopenia and dynapenia, has recently been recognized as a diabetic complication. However, the influence of accumulated AGEs on muscle mass and strength remains unclear. The present study aimed to evaluate the association of sarcopenia and dynapenia with accumulated AGEs in patients with type 2 diabetes. We recruited 166 patients with type 2 diabetes aged 30 years (mean age 63.2 ± 12.3 years; body mass index 26.3 ± 4.9 kg/m ; glycated hemoglobin 7.1 ± 1.1%). Skin autofluorescence as a marker of AGEs, limb skeletal muscle mass index, grip strength, knee extension strength and gait speed were assessed. Sarcopenia and dynapenia were observed in 7.2 and 13.9% of participants, respectively. Skin autofluorescence was significantly higher in patients with sarcopenia and dynapenia. Skin autofluorescence was the independent determinant for skeletal muscle mass index, grip strength, knee extension strength, sarcopenia and dynapenia. Accumulated AGEs could contribute to reduced muscle mass and strength, leading to sarcopenia and dynapenia in patients with type 2 diabetes. (徳島大学機関リポジトリ) ● Metadata: 114022 (出版サイトへのリンク) ● Publication site (DOI): 10.1111/jdi.13014 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30677242 ● Search Scopus @ Elsevier (PMID): 30677242 ● Search Scopus @ Elsevier (DOI): 10.1111/jdi.13014 (徳島大学機関リポジトリ: 114022, DOI: 10.1111/jdi.13014, PubMed: 30677242)
23.	Hiroyasu Mori and Yasunobu Tokuda : Differences and overlap between sarcopenia and physical frailty in older community-dwelling Japanese., Asia Pacific Journal of Clinical Nutrition, Vol.28, No.1, 157-165, 2019. (要約) This study showed that sarcopenia with frailty was had higher incidences of recurrent fall and poor HRQOL than robust older adults. Aging and poor energy, protein, and vitamin D intake, may be relevant factors for sarcopenia with frailty. (出版サイトへのリンク) ● Publication site (DOI): 10.6133/apjcn.201903_28(1).0021 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30896427 ● Search Scopus @ Elsevier (PMID): 30896427 ● Search Scopus @ Elsevier (DOI): 10.6133/apjcn.201903_28(1).0021 (DOI: 10.6133/apjcn.201903_28(1).0021, PubMed: 30896427)
24.	Hiroyasu Mori and Yasunobu Tokuda : Effect of whey protein supplementation after resistance exercise on the muscle mass and physical function of healthy older women: A randomized controlled trial., Geriatrics & Gerontology International, Vol.18, No.9, 1398-1404, 2018. (要約) The pre- to post-intervention increase in the skeletal muscle mass index was significantly higher for the exercise only group than for the protein supplementation only group (P =0.008), and significantly higher for the exercise and protein supplementation group than for either the exercise only (P =0.007) or protein supplementation only (P <0.001) groups. Similarly, the increase in grip strength and gait speed was significantly greater for the exercise and protein supplementation group than for the protein supplementation only group (grip strength P =0.014, gait speed P =0.026). (キーワード) Activities of Daily Living / Aged / Aged, 80 and over / Analysis of Variance / Body Composition / Dietary Supplements / Female / Follow-Up Studies / Healthy Volunteers / Humans / Independent Living / Japan / Multivariate Analysis / Muscle Strength / Muscle Strength Dynamometer / Reference Values / Regression Analysis / Resistance Training / Sarcopenia / Single-Blind Method / Whey Proteins (徳島大学機関リポジトリ) ● Metadata: 115110 (出版サイトへのリンク) ● Publication site (DOI): 10.1111/ggi.13499 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30113122 ● Search Scopus @ Elsevier (PMID): 30113122 ● Search Scopus @ Elsevier (DOI): 10.1111/ggi.13499 (徳島大学機関リポジトリ: 115110, DOI: 10.1111/ggi.13499, PubMed: 30113122)
25.	Akio Kuroda, Satoshi Taniguchi, Yuko Akehi, Hiroyasu Mori, Motoyuki Tamaki, Reiko Suzuki, Yinhua Otsuka and Munehide Matsuhisa : Accuracy and Time Delay of Glucose Measurements of Continuous Glucose Monitoring and Bedside Artificial Pancreas During Hyperglycemic and Euglycemic Hyperinsulinemic Glucose Clamp Study., Journal of Diabetes Science and Technology, Vol.11, No.6, 1096-1100, 2017. (要約) Both CGM and AP failed to follow plasma glucose values during nonphysiologically rapid glucose rising, but indicated accurate values during physiological glucose change. (キーワード) Adult / Biomarkers / Blood Glucose / Diabetes Mellitus, Type 2 / Female / Glucose Clamp Technique / Humans / Hypoglycemic Agents / Insulin / Insulin Infusion Systems / Male / Middle Aged / Monitoring, Ambulatory / Pancreas, Artificial / Point-of-Care Systems / Predictive Value of Tests / Reproducibility of Results / Retrospective Studies / Time Factors / Treatment Outcome (徳島大学機関リポジトリ) ● Metadata: 114040 (出版サイトへのリンク) ● Publication site (DOI): 10.1177/1932296817735122 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28992720 ● Search Scopus @ Elsevier (PMID): 28992720 ● Search Scopus @ Elsevier (DOI): 10.1177/1932296817735122 (徳島大学機関リポジトリ: 114040, DOI: 10.1177/1932296817735122, PubMed: 28992720)
26.	Hiroyasu Mori, Akio Kuroda, Michiko Araki, Reiko Suzuki, Satoshi Taniguchi, Motoyuki Tamaki, Yuko Akehi and Munehide Matsuhisa : Advanced glycation end products is a risk for muscle weakness in Japanese patients with type 1 diabetes., Journal of Diabetes Investigation, Vol.8, No.3, 377-382, 2017. (要約) Accumulation of advanced glycation end products (AGEs) is thought to contribute to muscle weakness in a diabetic animal model. Skin autofluorescence (AF) is a proposed marker for accumulation of AGEs in the skin. We aimed to investigate the relationship between AGEs accumulation, sarcopenia, and muscle function of Japanese patients with type 1 diabetes. Thirty-six patients with type 1 diabetes participated in this cross-sectional study. Sarcopenia parameters (skeletal muscle mass index (SMI) and knee extension strength) were compared with subcutaneous AGEs accumulation using skin AF. The prevalence of sarcopenia and impaired knee extension strength was 16.6% (male: 0.0%, female: 22.2%) and 47.2% (male: 22.2%, female: 55.6%), respectively. Knee extension strength was negatively correlated with skin AF (r²= 0.14, p < 0.05), but not with SMI. In conclusion, the AGEs accumulation might be one of the reasons of impaired lower limb muscle function in Japanese patients with type 1 diabetes. This article is protected by copyright. All rights reserved. (徳島大学機関リポジトリ) ● Metadata: 114021 (出版サイトへのリンク) ● Publication site (DOI): 10.1111/jdi.12582 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27727515 ● Search Scopus @ Elsevier (PMID): 27727515 ● Search Scopus @ Elsevier (DOI): 10.1111/jdi.12582 (徳島大学機関リポジトリ: 114021, DOI: 10.1111/jdi.12582, PubMed: 27727515)
27.	Hiroyasu Mori and Yasunobu Tokuda : Effect of increased daily intake of protein, combined with a program of resistance exercises, on the muscle mass and physical function of community-dwelling elderly women, The Journal of Aging Research & Clinical Practice, Vol.6, No.1, 56-61, 2016. (出版サイトへのリンク) ● Publication site (DOI): 10.14283/jarcp.2016.124 (文献検索サイトへのリンク) ● Search Scopus @ Elsevier (DOI): 10.14283/jarcp.2016.124 (DOI: 10.14283/jarcp.2016.124)
28.	Jin Temma, Munehide Matsuhisa, Toru Horie, Akio Kuroda, Hiroyasu Mori, Motoyuki Tamaki, Itsuro Endo, Ken-ichi Aihara, Masahiro Abe and Toshio Matsumoto : Non-invasive Measurement of Skin Autofluorescence as a Beneficial Surrogate Marker for Atherosclerosis in Patients with Type 2 Diabetes, The Journal of Medical Investigation : JMI, Vol.62, No.3-4, 126-129, 2015. (要約) Advanced glycation end-products (AGEs) are thought to play a major role in the pathogenesis of diabetic vascular complications. Skin autofluorescence (AF) was recently reported to represent tissue AGEs accumulation with a non-invasive method. The aim of the present study was to evaluate association between AF value and diabetic vascular complications, such as retinopathy, nephropathy and cervical atherosclerosis using the carotid intima-media thickness (IMT), an established marker of cardiovascular disease in patients with type 2 diabetes. A total of 68 patients with type 2 diabetes were enrolled in a cross-sectional manner. AGEs accumulation was measured with AF reader. Clinical parameters were collected at the time of AF and IMT measurement. Max-IMT was correlated with age and AF (r=0.407, p=0.001), but not with HbA1c, GA, and pentosidine. Also, AF was not correlated with HbA1c, GA and pentosidine, but was correlated with age (r=0.560, p<0.001), duration of diabetes (r=0.256, p<0.05). Multivariate regression analysis revealed that AF, but not age, was an independent determinant of max-IMT. In conclusion, AF might be a beneficial surrogate marker for evaluating carotid atherosclerosis in patients with type 2 diabetes non-invasively. J. Med. Invest. 62: 126-129, August, 2015. (徳島大学機関リポジトリ) ● Metadata: 111266 (出版サイトへのリンク) ● Publication site (DOI): 10.2152/jmi.62.126 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26399335 ● Summary page in Scopus @ Elsevier: 2-s2.0-84942054596 (徳島大学機関リポジトリ: 111266, DOI: 10.2152/jmi.62.126, PubMed: 26399335, Elsevier: Scopus)
29.	Hiroyasu Mori : Effect of timing of protein and carbohydrate intake after resistance exercise on nitrogen balance in trained and untrained young men., Journal of Physiological Anthropology, Vol.33, 2014. (要約) Subjects were 10 trained healthy men (mean age, 23 ± 4 years; height, 173.8 ± 3.1 cm; weight, 72.3 ± 4.3 kg) and 10 untrained healthy men (mean age, 23 ± 1 years; height, 171.8 ± 5.0 cm; weight, 64.5 ± 5.0 kg). All subjects performed four sets of 8 to 10 repetitions of a resistance exercise (comprising bench press, shoulder press, triceps pushdown, leg extension, leg press, leg curl, lat pulldown, rowing, and biceps curl) at 80% one-repetition maximum. After each resistance exercise session, subjects were randomly divided into two groups with respect to intake of protein (0.3 g/kg body weight) and carbohydrate (0.8 g/kg body weight) immediately after (P0) or 6 h (P6) after the session. All subjects were on an experimental diet that met their individual total energy requirement. We assessed whole-body protein metabolism by measuring nitrogen balance at P0 and P6 on the last 3 days of exercise training. (キーワード) Adult / Athletes / Dietary Carbohydrates / Dietary Proteins / Energy Intake / Humans / Male / Nitrogen / Resistance Training / Time Factors / Weight Lifting / Young Adult (出版サイトへのリンク) ● Publication site (DOI): 10.1186/1880-6805-33-24 (文献検索サイトへのリンク) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25096224 ● Search Scopus @ Elsevier (PMID): 25096224 ● Search Scopus @ Elsevier (DOI): 10.1186/1880-6805-33-24 (DOI: 10.1186/1880-6805-33-24, PubMed: 25096224)

総説・解説:

1.	黒田暁生, 鈴木麗子, 冨永ゆかり, 森博康, 岡本美鈴, 松久宗英 : 1 か月で 23 回インスリンポンプ注入が 3 時間以上中断しており，ケトアシドーシス症状を繰り返していた 1 型糖尿病の一例, 第22回日本糖尿病インフォマティクス学会年次学術集会, 2022年8月.
2.	森博康 : サルコペニア予防を目的とした食事療法, 栄養学雑誌, Vol.79, No.5, 18, 2021年10月.
3.	松久宗英, 森博康 : 糖尿病診療におけるAIの診療支援, 糖尿病·内分泌代謝科, Vol.52, No.6, 588-593, 2021年6月. (キーワード) artificial intelligence (AI) / electronic health record (EHR) / personal health record / deep learning (文献検索サイトへのリンク) ● CiNii @ 国立情報学研究所 (CRID): 1520010381271148544 (CiNii: 1520010381271148544)
4.	森博康, 松久宗英 : テレビカンファレンスシステムを活用した遠隔栄養指導の有用性と展望, 臨床栄養, Vol.135, No.1, 2019年7月.
5.	森博康, 鈴木麗子, 黒田暁生, 田蒔基行, 明比祐子, 松久宗英, 荒木迪子, 阪上浩 : 1型糖尿病患者における皮下蓄積AGEsとサルコペニアとの関連の検討, 成人病と生活習慣病, Vol.46, No.5, 608-609, 2016年5月.

国際会議:

1.	Yosuke Kaneko, Saya Yasui, Minae Hosoi, Akihiro Tani, Hiroki Yamagami, Hiroyasu Mori, Tomoyo Hara, Yukari Mitsui, Kiyoe Kurahashi, Sumiko Yoshida, Shingen Nakamura, Akio Kuroda, Toshiki Otoda, Tomoyuki Yuasa, Itsuro Endo, Takeshi Soeki, Munehide Matsuhisa, Masahiro Abe and Ken-ichi Aihara : Dehydroepiandrosterone sulfate and skeletal muscle disorders in patients with type 2 diabetes, IDF-WPR Congress 2023/15th Scientific Meeting of AASD, Tokyo, Jul. 2023.
2.	Hiroyasu Mori and Tokuda Yasunobu : Effect of Whey Protein Intake after Resistance Exercise on Skeletal Muscle Mass, Strength, and Quality of Life in Older Adults with Sarcopenia: A Randomized Controlled Trial, The 22nd International Union of Nutritional Sciences-International Congress of Nutrition, Dec. 2022.
3.	Taro Kishida, Uchida Kenji, Yoshida Eriko, Hiroyasu Mori and Tokuda Yasunobu : Dietary fish protein improves skeletal muscle weight., The 22nd International Union of Nutritional Sciences-International Congress of Nutrition, Dec. 2022.
4.	Uchida Kenji, Hiroyasu Mori, Yoshida Eriko and Tokuda Yasunobu : Effects of Alaska pollack protein intake on skeletal muscle mass and strength in older people requiring for nursing care., The 22nd International Union of Nutritional Sciences-International Congress of Nutrition, Dec. 2022.
5.	Yoshida Eriko, Hiroyasu Mori, Uchida Kenji and Tokuda Yasunobu : Effects of Alaska pollack protein intake on skeletal muscle mass and strength in healthy older women., The 22nd International Union of Nutritional Sciences-International Congress of Nutrition, Dec. 2022.
6.	Hiroyasu Mori and Tokuda Yasunobu : Effect of Whey Protein Intake after Resistance Exercise on Skeletal Muscle Mass, Strength, and Quality of Life in Older Adults with Sarcopenia: A Randomized Controlled Trial, The 8th Asian Congress of Dietetics, Aug. 2022.
7.	Akio Kuroda, Misuzu Yamada, Asami Okada, Yukari Tominaga, Kyoka Joh, Natsuki Ohrei, Hiroyasu Mori and Munehide Matsuhisa : Circulating cell free DNA and its clinical application, The 15th Symposium of the Institute Network for Biomedical Sciences, Nov. 2020.
8.	Akio Kuroda, Misuzu Yamada, Yuichi Takashi, Mami Ohishi, Hiroyasu Mori, Masashi Ishizu, Reiko Suzuki, Yinhua Otsuka, Yukari Tominaga and Munehide Matsuhisa : Detection of Vascular Endothelial Cell DNA in the Circulation Using Dual Amplification Refractory Mutation System PCR., American Diabetes Association 79th Scientific Sessions, San Francisco, Jun. 2019.
9.	Munehide Matsuhisa, Hiroyasu Mori, Mami Ohishi, Masashi Ishizu, Reiko Suzuki, Ineko Takikawa, Satoshi Taniguchi, Motoyuki Tamaki, Yuko Akehi, Kiyoe Kurahashi, Sumiko Yoshida, Itsuro Endo, Ken-ichi Aihara, Makoto Funaki and Akio Kuroda : The risk factors for rapid decline of renal function in Japanese patients with diabetes mellitus, American Diabetes Association 78th Scientific Sessions, Orlando, Jun. 2018.
10.	Akio Kuroda, J Temma, T Horie, Hiroyasu Mori, Motoyuki Tamaki, Ken-ichi Aihara and Munehide Matsuhisa : Noninvasive measurement of skin autofluorescence as a beneficial surrogate marker for atherosclerosis in patients with type 2 diabetes, American Diabetes Association 75th Scientific Sessions, 2015.

国内講演発表:

1.	単暁, 田木真和, 小西健史, 森博康, 松久宗英, 廣瀬隼 : AIを用いた糖尿病患者に対する食事提案システムの開発, 医療情報学連合大会論文集 43回, 995-997, 2023年11月.
2.	黒田暁生, 岡田朝美, 森博康, 冨永ゆかり, 石津将, 松久宗英 : 循環血中遊離 DNA を標的とした血管内皮細胞傷害の検出, 第38回日本糖尿病合併症学会, 2023年10月.
3.	森博康, 徳田泰伸 : レジスタンス運動後のロイシン摂取がサルコペニア治療に与える効果:脱トレーニングを伴う無作為化比較試験, 第70回日本栄養改善学会学術総会, 2023年9月.
4.	森博康, 谷口諭, 玉木悠, 野村友美, 鈴木麗子, 黒田暁生, 明比祐子, 長嶋伸光, 比木武, 松久宗英 : 2型糖尿病患者の臨床用PHRを用いた自動支援メッセージがセルフモニタリングや体重管理に与える効果:無作為化比較試験, 第23回日本糖尿病インフォマティクス学会年次学術集会 YIA優秀演題賞受賞, 2023年8月.
5.	森博康 : 2型糖尿病患者の臨床用PHRを用いた自動支援メッセージがセルフモニタリングや体重管理に与える効果:無作為化比較試験, 第23回日本糖尿病インフォマティクス学会年次学術集会, 2023年8月.
6.	森博康 : 2型糖尿病患者におけるダイナペニアとサルコペニアの総エネルギー・栄養素摂取量等の影響:横断的検証, 第65回日本糖尿病学会年次学術集会, 2022年5月.
7.	乙田敏城, 湯浅智之, 関根明子, 上元良子, 森博康, 原倫世, 田蒔基行, 玉置俊晃, 松久宗英, 粟飯原賢一 : SGLT2 阻害薬投与による蛋白尿減少および炎症抑制効果の検討, 第 65 回日本糖尿病学会年次学術集会, 2022年5月.
8.	乙田敏城, 湯浅智之, 関根明子, 上元良子, 森博康, 原倫世, 田蒔基行, 玉置俊晃, 松久宗英, 粟飯原賢一 : SGLT2阻害薬投与による蛋白尿減少および炎症抑制効果の検討, 第65回日本糖尿病学会年次学術集会, 2022年5月.
9.	森博康, 徳田泰伸, 吉田恵里子, 内田健志, 松久宗英 : スケソウダラ速筋タンパクの摂取が要介護高齢者の骨格筋量と筋力，身体機能に与える効果:単群前後比較試験, 第33回日本老年医学会四国地方会, 2022年1月.
10.	乙田敏城, 湯浅智之, 関根明子, 上元良子, 森博康, 田蒔基行, 玉置俊晃, 松久宗英, 粟飯原賢一 : SGLT2阻害薬の投与が蛋白尿減少効果をもたらす要因の検討, 第6回日本糖尿病・生活習慣病ヒューマンデータ学会, 2021年12月.
11.	森博康, 秦誠倫, 安田哲行, 山本恒彦, 馬屋原豊, 良本佳代子, 吉内和富, 吉田守美子, 黒田暁生, 松久宗英 : 1型糖尿病における低IGF-1血症が骨格筋量の低下やサルコペニア合併に及ぼす影響の検討:横断的研究, 第20回日本先進糖尿病治療研究会・第18回1型糖尿病研究会, 2021年11月.
12.	森博康, 徳田泰伸, 内田健志, 吉田恵里子 : スケソウダラ速筋タンパクの摂取が高齢者の骨格筋量と身体機能，健康関連QOLに与える効果:二重盲検無作為化プラセボ対照試験, 第8回日本サルコペニア・フレイル学会大会, 2021年11月.
13.	森博康 : サルコペニア治療を目的としたレジスタンス運動と乳清たんぱく質の栄養摂取タイミングの有用性, ジャパンミルクコングレス2021, 2021年11月.
14.	岡田朝美, 山田美鈴, 森博康, 明比祐子, 倉橋清衛, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 松久宗英, 黒田暁生 : 1型糖尿病患者における膵β細胞傷害の定量化の試み, 日本糖尿病学会中国四国地方会第59回総会, 2021年10月.
15.	森博康, 徳田泰伸, 内田健志, 吉田恵里子 : スケソウダラ速筋タンパクの摂取が要介護高齢者の骨格筋量と筋力，身体機能に与える効果:単群前後比較試験, 第68回日本栄養改善学会学術総会, 2021年10月.
16.	森博康 : 受賞講演:サルコペニア予防を目的とした食事療法の創出に関わる臨床研究, 日本栄養改善学会, 2021年10月.
17.	森博康, 徳田泰伸 : レジスタンス運動後の乳清たんぱく質の摂取が高齢者のサルコペニア治療と身体的QOLに与える効果:ランダム化比較試験, 第76回日本体力医学会大会, 2021年9月.
18.	黒田暁生, 石津将, 鶴尾美穂, 森博康, 明比祐子, 岡本美鈴, 鈴木麗子, 寺澤敏秀, 松久宗英 : 持続グルコースモニタリングの推定HbA1c値と実測HbA1c値との解離に関する検討, 第21回日本糖尿病インフォマティクス学会年次学術集会, 2021年8月.
19.	岡田朝美, 山田美鈴, 森博康, 明比祐子, 倉橋清衛, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 松久宗英, 黒田暁生 : 循環血中遊離DNAを用いた膵β細胞障害の新規検出法の確立, 第263回徳島医学会学術集会, 2021年8月.
20.	森博康, 徳田泰伸, 吉田恵里子, 内田健志 : スケソウダラ速筋タンパクの摂取が地域在住高齢者の骨格筋量や身体機能に与える効果:二重盲検無作為化プラセボ対照試験, 第63回日本老年医学会学術集会, 2021年6月.
21.	森博康, 黒田暁生, 吉田守美子, 安田哲行, 馬屋原豊, 清水彩洋子, 良本佳代子, 吉内和富, 山本恒彦, 松久宗英 : 2型糖尿病患者のサルコペニア合併に血清グリコアルブミン/HbA1cが関連する, 第64回日本糖尿病学会年次学術集会, 2021年5月.
22.	松久宗英, 森博康, 黒田暁生 : 高齢 1 型糖尿病の病態と診療上の課題, 第64回日本糖尿病学会年次学術集会, 2021年5月.
23.	森博康, 黒田暁生, 吉田守美子, 安田哲行, 馬屋原豊, 清水彩洋子, 良本佳代子, 吉内和富, 山本恒彦, 下村伊一郎, 松久宗英 : 2型糖尿病患者におけるダイナぺニアとサルコペニアの臨床的特徴, 日本糖尿病学会中国四国地方会第58総会, 2020年10月.
24.	黒田暁生, 石津将, 鶴尾美穂, 森博康, 明比祐子, 岡本美鈴, 鈴木麗子, 寺澤敏秀, 松久宗英 : 持続グルコースモニタリングの推定HbA1c値と実測HbA1c値との解離に関する検討, 日本糖尿病学会中国四国地方会第58総会, 2020年10月.
25.	石津将, 森博康, 明比祐子, 黒田暁生, 田蒔基行, 吉田守美子, 粟飯原賢一, 藍場元弘, 河野友晴, 橋田誠一, 松久宗英 : 糖尿病性腎症における尿アディポネクチンの意義(第2報), 日本糖尿病学会中国四国地方会第58総会, 2020年10月.
26.	清水彩洋子, 馬屋原豊, 清水成, 畑雅久, 藤田洋平, 桂央士, 良本佳代子, 安田哲行, 山本恒彦, 吉内和富, 吉田守美子, 良本佳代子, 黒田暁生, 森博康, 下村伊一郎, 松久宗英 : 2型糖尿病の肝線維化が血清IGF 1と筋肉量・筋力低下に与える影響, 第63回日本糖尿病学会年次学術集会, 2020年10月.
27.	秦誠倫, 森博康, 竹本有里, 藤井浩平, 永田慎平, 山本裕一, 狭間洋至, 吉田守美子, 吉内和富, 山本恒彦, 馬屋原豊, 良本佳代子, 黒田暁生, 安田哲行, 下村伊一郎, 松久宗英 : 1型糖尿病患者のサルコペニアには血清IGF-1低値が関連する, 第63回日本糖尿病学会年次学術集会, 2020年10月.
28.	森博康, 黒田暁生, 吉田守美子, 安田哲行, 馬屋原豊, 清水彩洋子, 良本佳代子, 吉内和富, 山本恒彦, 下村伊一郎, 松久宗英 : 1型および2型糖尿病患におけるダイナぺニアとサルコペニアの臨床的特徴 iDIAMOND Studyからの報告, 第63回日本糖尿病学会年次学術集会, 2020年10月.
29.	黒田暁生, 石津将, 鶴尾美穂, 森博康, 明比祐子, 岡本美鈴, 鈴木麗子, 寺澤敏秀, 松久宗英 : 持続グルコースモニタリングの推定HbA1c値と実測HbA1c値との解離に関する検討, 第20回日本糖尿病情報学会年次学術集会, 2020年9月.
30.	徳里望, 阪上浩, 堤理恵, 黒田雅士, 升本早枝子, 森万理恵, 別府香名, 堤理恵, 森博康, 松久宗英, 阪上浩, 神田彩恵, 堤理恵, 三島優奈, 上嶋奈々子, 松本裕華, 原加奈子, 黒田雅士, 阪上浩 : ロイシンの抗動脈硬化作用の検討, 糖尿病, Vol.63, No.9, 657, 2020年9月. (キーワード) Catechin 肥満(実験的) Biflavonoids Proanthocyanidins 認知機能低下(実験的) 消化管微生物叢 Procyanidin マウス動物 / 血液透析糸球体濾過量腎不全-慢性(治療,合併症) 糖尿病(合併症) 味覚障害(病因) 味蕾 Leptin(血液) G-Protein-Coupled Receptors T1R Receptor ヒト / Cholesterol(血液) Leucine(治療的利用) LDL Cholesterol(血液) 動脈硬化症(薬物療法,実験的) マウス動物メス
31.	森博康, 徳田泰伸 : サルコペニア治療を目的とした食事・運動療法の介入後の筋肉や筋力の長期的持続効果の検証, 第62回日本老年医学会学術集会, 2020年8月.
32.	森博康, 黒田暁生, 安田哲行, 馬屋原豊, 清水彩洋子, 良本佳代子, 吉内和富, 山本恒彦, 吉田守美子, 松久宗英 : 2型糖尿病のダイナぺニアの臨床的特徴の検討, 第54回日本成人病(生活習慣病)学会, 2020年1月.
33.	森万理江, 別府香名, 堤理恵, 森博康, 松久宗英, 阪上浩 : 糖尿病および透析患者における味覚障害と舌味覚受容体発言の関連について, 日本糖尿病学会中国四国地方会第57回総会, 2019年12月.
34.	鶴尾美穂, 住友正治, 小松まち子, 大島康志, 坂東智子, 森博康, 石津将, 髙橋保子, 粟飯原賢一, 松久宗英, 宇都宮正登 : 徳島市医師会糖尿病腎症重症化予防パイロット事業後アンケート結果, 日本糖尿病学会中国四国地方会第57回総会, 2019年12月.
35.	森博康, 徳田泰伸 : サルコペニア治療を目的とした食事と運動療法の併用介入が筋肉量や身体機能に与える影響, 第9回日本リハビリテーション栄養学会年次学術集会, 2019年11月.
36.	森博康, 黒田暁生, 松久宗英 : 高齢糖尿病患者の肥満と筋障害との関連, 第40回日本肥満学会・第37回日本肥満症治療学会, 2019年11月.
37.	石津将, 森博康, 大石真実, 鈴木麗子, 岡本美鈴, 明比祐子, 黒田暁生, 田蒔基行, 髙士祐一, 吉田守美子, 粟飯原賢一, 藍場元弘, 河野友晴, 橋田誠一, 松久宗英 : 糖尿病性腎臓病における尿中アディポネクチン排泄の臨床的意義, 第40回日本肥満学会・第37回日本肥満症治療学会, 2019年11月.
38.	石津将, 鶴尾美穂, 豊崎纏, 粟飯原賢一, 坂東智子, 住友正治, 古川浩, 宮本泰文, 小松まち子, 大島康志, 桜井えつ, 若槻真吾, 岡川和人, 林正, 松村光博, 小川紘一, 安岡正治, 細井恵美子, 丸岡重代, 西岡恵子, 髙橋保子, 森博康, 松久宗英, 宇都宮正登 : 徳島市医師会糖尿病腎症重症化予防パイロット事業の報告, 第19回日本糖尿病情報学会年次学術集会, 2019年8月.
39.	鈴木麗子, 森博康, 石津将, 玉木悠, 谷口諭, 黒田暁生, 松久宗英 : スマートスピーカーを活用した個別化糖尿病自己管理支援システムの開発糖尿病患者の行動変容を目指して, 第19回日本糖尿病情報学会年次学術集会, 2019年8月.
40.	森博康, 徳田泰伸 : サルコペニア治療を目的とした食事と運動療法の併用介入が栄養状態や身体機能，QOL改善に与える影響, 第61回日本老年医学会学術集会, 2019年6月.
41.	鶴尾美穂, 豊﨑纏, 小松まち子, 住友正治, 大島康志, 粟飯原賢一, 森博康, 石津将, 岡川和人, 小川絋一, 古川浩, 桜井えつ, 林正, 坂東智子, 細井恵美子, 松村光輝, 宮本泰文, 保岡正治, 高橋保子, 丸岡重代, 西岡恵子, 宇都宮正登, 松久宗英 : 徳島市医師会糖尿病腎症重症化予防パイロット事業の取組, 第62回日本糖尿病学会年次学術集会, 2019年5月.
42.	石津将, 森博康, 大石真実, 鈴木麗子, 岡本美鈴, 明比祐子, 黒田暁生, 田蒔基行, 髙士祐一, 吉田守美子, 粟飯原賢一, 藍場元弘, 河野友晴, 橋田誠一, 松久宗英 : 糖尿病性腎臓病における尿中アディポネクチン排泄率の臨床的意義の検討, 第62回日本糖尿病学会年次学術集会, 2019年5月.
43.	森博康, 玉木悠, 谷口諭, 野村友美, 大塚銀花, 岡本美鈴, 鈴木麗子, 黒田暁生, 松久宗英 : テレビカンファレンスシステム活用遠隔栄養指導が2型糖尿病患者の病態や食行動に及ぼす影響:無作為化比較試験, 第62回日本糖尿病学会年次学術集会, 2019年5月.
44.	松久宗英, 森博康, 谷口諭, 玉木悠, 黒田暁生 : EHRと連携するPHR「電子糖尿病ダイアリー」, 第62回日本糖尿病学会年次学術集会シンポジウム, 2019年5月.
45.	別府香名, 堤理恵, 森博康, 平野春美, 土田健司, 松久宗英, 武田憲昭, 阪上浩 : 透析患者における味覚障害と味覚受容体T1R3遺伝子の発現の関連, 第258回徳島医学会学術集会ポスターセッション, 2019年2月.
46.	松久宗英, 森博康, 谷口諭, 石津将, 明比祐子, 玉木悠, 黒田暁生 : 徳島県での地域医療連携基盤の構築とデータ利活用への試み, 第3回日本糖尿病・生活習慣病ヒューマンデータ学会シンポジウム3, 2018年12月.
47.	石津将, 森博康, 大石真実, 鈴木麗子, 明比祐子, 黒田暁生, 田蒔基行, 髙士祐一, 吉田守美子, 粟飯原賢一, 藍場元弘, 河野友晴, 橋田誠一, 松久宗英 : 糖尿病性腎臓病における尿アディポネクチンの意義, 日本糖尿病学会中国四国地方会第56回総会, 2018年10月.
48.	森博康, 黒田暁生, 石津将, 髙士祐一, 谷口諭, 田蒔基行, 明比祐子, 松久宗英 : 2型糖尿病患者における肥満と筋傷害との関連の検証, 第39回日本肥満学会, 2018年10月.
49.	森博康, 荒木迪子, 黒田暁生, 石津将, 髙士祐一, 谷口諭, 倉橋清衛, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 田蒔基行, 明比祐子, 松久宗英 : 1型糖尿病患者の血清IGF-1とサルコペニア合併に関する横断的検証, 第18回日本内分泌学会四国支部学術集会, 2018年9月.
50.	森博康, 玉木悠, 谷口諭, 野村友美, 鈴木麗子, 瀧川稲子, 黒田暁生, 松久宗英 : テレビカンファレンスシステムを用いた遠隔栄養指導の介入が2型糖尿病患者の代謝状態や食行動に与える影響, 第18回日本糖尿病情報学会, 2018年8月.
51.	谷口諭, 玉木悠, 森博康, 鈴木麗子, 田蒔基行, 白神敦久, 明比祐子, 黒田暁生, 松久宗英 : 電子糖尿病ダイアリーの糖尿病患者の自己管理への効果と課題の検証, 第18回日本糖尿病情報学会, 2018年8月.
52.	森博康, 徳田泰伸 : サルコペニア治療を目的とした食事と運動療法の併用介入が筋肉量や身体機能，QOL改善に与える影響・無作為比較化試験, 平成30年度全国栄養士大会, 2018年7月.
53.	髙士祐一, 石津将, 森博康, 黒田暁生, 松久宗英 : 骨産生ホルモンであるオステオカルシンは1型糖尿病患者の体脂肪を制御する, 第118回日本内科学会四国地方会, 2018年6月.
54.	髙士祐一, 石津将, 森博康, 宮下和幸, 坂本扶美枝, 片上直人, 松岡孝昭, 安田哲行, 橋田誠一, 黒田暁生, 松久宗英 : 骨産生ホルモンucOCは1型糖尿病患者の体脂肪率と関係する, 第61回日本糖尿病学会年次学術集会, 2018年5月.
55.	森博康, 鈴木麗子, 瀧川稲子, 石津将, 大石真実, 谷口諭, 明比祐子, 黒田暁生, 松久宗英 : 糖尿病腎症の急速進行に関連するリスク因子の検証:前向き観察研究, 第61回日本糖尿病学会年次学術集会, 2018年5月.
56.	田蒔基行, 髙士祐一, 乙田敏城, 福本誠二, 黒田暁生, 明比祐子, 森博康, 谷口諭, 鈴木麗子, 山田美鈴, 石津将, 大石真実, 白神敦久, 粟飯原賢一, 船木真理, 松久宗英 : かかりつけ患者に対するSGLT2阻害薬の投与開始タイミングの特徴と投与開始後の体重・eGFR・ALT・脂質代謝の変化, 第61回日本糖尿病学会年次学術集会, 2018年5月.
57.	藤本侑希, 渡辺敏弘, 森本彩, 熊本はな, 須藤浩三, 吉田智一, 森博康, 松久宗英, 秦明子, 船木真理, 山本真弓, 橋田誠一 : 腎障害予測指標としての尿中アディポネクチンに関する検討, 第21回日本病態栄養学会年次学術集会, 2018年1月.
58.	大石真実, 森博康, 鈴木麗子, 明比祐子, 黒田暁生, 田蒔基行, 谷口諭, 石津将, 阪上浩, 松久宗英 : 急速進行性糖尿病腎症に関連するリスク因子の検討, 日本糖尿病学会中国四国地方会第55回総会抄録集, 2017年11月.
59.	森博康, 大石真実, 鈴木麗子, 黒田暁生, 谷口諭, 田蒔基行, 明比祐子, 倉橋清衛, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 船木真理, 松久宗英 : 2型糖尿病患者における末梢神経障害の合併が骨格筋力の質的低下に及ぼす影響, 第32回日本糖尿病合併症学会, 2017年10月.
60.	藤本侑希, 渡辺敏弘, 森博康, 秦明子, 山本真弓, 橋田誠一 : 尿中アディポネクチンの腎障害指標に関する研究, 第57回日本臨床化学会年次学術集会, 2017年10月.
61.	藤本侑希, 渡辺敏弘, 森博康, 秦明子, 山本真弓, 橋田誠一 : 尿中アディポネクチンの腎障害予測マーカーに関する検討, 第64回日本栄養改善学会学術総会, 2017年9月.
62.	荒木迪子, 森博康, 黒田暁生, 鈴木麗子, 大石真実, 谷口諭, 田蒔基行, 明比祐子, 阪上浩, 倉橋清衛, 近藤剛史, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 船木真理, 松久宗英 : 1型糖尿病患者における血清IGF-1とサルコペニア罹患との関連, 第60回日本糖尿病学会年次学術集会, 2017年5月.
63.	森博康, 黒田暁生, 荒木迪子, 鈴木麗子, 大石真実, 谷口諭, 田蒔基行, 明比祐子, 倉橋清衛, 近藤剛史, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 船木真理, 松久宗英 : 2型糖尿病患者における皮下AGE蓄積が筋機能低下に及ぼす影響, 第60回日本糖尿病学会年次学術集会抄録集, 2017年5月.
64.	谷口諭, 天満仁, 黒田暁生, 堀江徹, 森博康, 鈴木麗子, 浅野弥生, 荒木迪子, 玉木悠, 松久宗英 : EHR自己測定機器と連係したPHRの開発と有用性の検証, 第60回日本糖尿病学会年次学術講演会抄録集, 2017年5月.
65.	藤本侑希, 渡辺敏弘, 森本彩, 熊本はな, 須藤浩三, 吉田智一, 森博康, 松久宗英, 秦明子, 船木真理, 山本真弓, 橋田誠一 : 尿中アディポネクチンの腎障害予測マーカーに関する研究, 糖尿病, Vol.60, No.Suppl.1, 2017年5月.
66.	荒木迪子, 森博康, 黒田暁生, 鈴木麗子, 大石真実, 谷口諭, 田蒔基行, 明比祐子, 阪上浩, 松久宗英 : 1型糖尿病患者の血清IGF-1がサルコペニア羅患に及ぼす影響, 第20回日本病態栄養学会年次学術集会, 2017年1月.
67.	森博康, 黒田暁生, 荒木迪子, 鈴木麗子, 大石真実, 谷口諭, 田蒔基行, 明比祐子, 倉橋清衛, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 船木真理, 松久宗英 : 2型糖尿病患者におけるサルコペニアのリスク因子解析, 第51回日本成人病学会学術集会, 2017年1月.
68.	大石真実, 谷口諭, 明比祐子, 森博康, 玉木悠, 黒田暁生, 田蒔基行, 荒木迪子, 阪上浩, 松久宗英 : eGFR変化量を用いた透析導入高リスク群抽出アルゴリズムの妥当性の検討, 日本糖尿病学会中国四国地方会第54回総会, 2016年11月.
69.	谷口諭, 天満仁, 黒田暁生, 堀江徹, 森博康, 鈴木麗子, 浅野弥生, 荒木迪子, 玉木悠, 松久宗英 : EHRと連係したPHRの開発と有用性の検証, 日本糖尿病学会中国四国地方会第54回総会, 2016年11月.
70.	荒木迪子, 森博康, 黒田暁生, 鈴木麗子, 大石真実, 谷口諭, 田蒔基行, 明比祐子, 阪上浩, 倉橋清衛, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 船木真理, 松久宗英 : 1型糖尿病患者の血清IGF-1がサルコペニア罹患に及ぼす影響, 日本糖尿病学会中国四国地方会第54回総会, 2016年11月.
71.	森博康, 黒田暁生, 荒木迪子, 鈴木麗子, 大石真実, 谷口諭, 田蒔基行, 明比祐子, 倉橋清衛, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 船木真理, 松久宗英 : 2型糖尿病患者におけるAGE蓄積とサルコペニアとの関連の検討, 日本糖尿病学会中国四国地方会第54回総会, 2016年11月.
72.	荒木迪子, 森博康, 黒田暁生, 鈴木麗子, 大石真実, 谷口諭, 田蒔基行, 明比祐子, 阪上浩, 倉橋清衛, 吉田守美子, 遠藤逸朗, 粟飯原賢一, 船木真理, 松久宗英 : 1型糖尿病患者の血清IGF-1がサルコペニア罹患に及ぼす影響, 第14回1型糖尿病研究会, 2016年11月.
73.	谷口諭, 天満仁, 黒田暁生, 堀江徹, 森博康, 鈴木麗子, 浅野弥生, 荒木迪子, 玉木悠, 松久宗英 : EHRとPHRの開発と従来の紙媒体記録との比較検証, 第16回日本糖尿病情報学会年次学術集会, 2016年9月.
74.	荒木迪子, 森博康, 鈴木麗子, 谷口諭, 田蒔基行, 明比祐子, 黒田暁生, 阪上浩, 松久宗英 : 1型糖尿病患者における血清IGF-1の低下とサルコペニア羅漢との関連, 第253回徳島医学会学術集会, 2016年7月.
75.	谷口諭, 松久宗英, 森博康, 黒田暁生, 玉木悠 : PHR活用による糖尿病自己管理行動への効果の検討, ITヘルスケア学会第10回記念学術大会, 2016年5月. (キーワード) PHR / 自己管理行動 / 糖尿病 (diabetes mellitus)
76.	森博康, 荒木迪子, 鈴木麗子, 黒田暁生, 田蒔基行, 明比祐子, 松久宗英 : 1型糖尿病患者における皮下AGEsの蓄積が筋機能低下に及ぼす影響, 第59回日本糖尿病学会年次学術集会, 2016年5月.
77.	森博康, 松久宗英, 黒田暁生, 田蒔基行, 谷口諭, 玉木悠, 大塚明廣, 野間喜彦, 徳島県医師会糖尿病対策班 : 徳島県の糖尿病診療の現状と課題∼平成22年と26年の比較∼, 第53回日本糖尿病学会中国・四国地方会米子コンベンションセンター, 2015年10月.
78.	荒木迪子, 森博康, 奥村仙示, 多々納浩, 田蒔基行, 黒田暁生, 阪上浩, 松久宗英 : 食事エネルギー密度は日本人2型糖尿病患者の肥満と関連する, 第53回日本糖尿病学会中国四国地方会米子コンベンションセンター, 2015年10月.
79.	森博康, 松久宗英, 黒田暁生, 田蒔基行, 谷口諭, 玉木悠, 野間喜彦, 大塚明廣 : 徳島県における糖尿病の治療中断と地域医療連携の推進に関連する医療側の課題の検討, 第15回日本糖尿病情報学会年次学術集会, 2015年8月.
80.	荒木迪子, 森博康, 奥村仙示, 鞍田三貴, 福尾惠介, 田蒔基行, 黒田暁生, 阪上浩, 松久宗英 : 低エネルギー密度食が2型糖尿病患者の食行動や代謝改善に与える効果の検討, 第251回徳島医学会学術集会ポスター, 2015年8月.
81.	玉木悠, 松久宗英, 黒田暁生, 田蒔基行, 谷口諭, 森博康 : IHE統合プロファイルを用いた複数医療連携ネットワークを統合したEHRの構築, 第19回日本医療情報学会春季学術大会, 2015年6月.
82.	天満仁, 堀江徹, 森博康, 黒田暁生, 松久宗英 : 2型糖尿病患者における皮下AGEと糖尿病血管合併症との関連の検討, 第58回日本糖尿病学会年次学術集会口演, 2015年5月.

その他・研究会:

1.	玉木悠, 松久宗英, 森博康, 谷口諭 : IHEITIを活用したID-Linkと連携した糖尿病向けPHRの研究開発, 第8回全国ID-Link研究会, 2019年11月.
2.	Hiroyasu Mori, Akio Kuroda, Michiko Araki, Reiko Suzuki, Mami Ohishi, Satoshi Taniguchi, Motoyuki Tamaki, Yuko Akehi, Hiroshi Sakaue, Kiyoe Kurahashi, Takeshi Kondo, Sumiko Yoshida, Itsuro Endo, Ken-ichi Aihara, Makoto Funaki and Munehide Matsuhisa : Advanced glycation end-products are a risk for muscle weakness in patients with type2 diabetes., American Diabetes Association 78th Scientific Sessions, Jun. 2017.
3.	Akio Kuroda, Satoshi Taniguchi, Akehi Yuko, Hiroyasu Mori, Motoyuki Tamaki, Suzuki Reiko, Hwa In and Munehide Matsuhisa : The comparison of glucose readings of continuous glucose monitoring and bedside artificial pancreas during glucose clamp study, American Diabetes Association 76th Scientific Sessions, Jun. 2016.
4.	Akio Kuroda, Satoshi Taniguchi, Akehi Yuko, Hiroyasu Mori, Motoyuki Tamaki, Suzuki Reiko, Hwa In and Munehide Matsuhisa : The comparison of glucose readings of continuous glucose monitoring and bedside artificial pancreas during glucose clamp study, Advanced Technologiies & Treatments for Diabetes, Feb. 2016.
5.	Akio Kuroda, Tenma Jin, Horie Toru, Hiroyasu Mori, Motoyuki Tamaki, Ken-ichi Aihara and Munehide Matsuhisa : Non-invasive measurement of skin autofluorescence as a beneficial surrogate marker for atherosclerosis in patients with type 2 diabetes., 第75回アメリカ糖尿病学会ポスター発表, Jun. 2015.

科学研究費補助金 (KAKEN Grants Database @ NII.ac.jp)

茶カテキンの食品機能性に注目した新たなサルコペニア予防と治療方法の創出 (研究課題/領域番号: 23K10799 )
高齢糖尿病患者の疾患性サルコペニア治療を目的とした食事・運動療法の創出 (研究課題/領域番号: 18K17924 )
サルコぺニア予防のための安全かつ簡単な運動と効果的な栄養摂取プログラムの開発 (研究課題/領域番号: 25750353 )
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