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Tokushima University > Research Clusters > Research Clusters (Prioritized) > 1802003 がんの統合的診断・治療を目指した分子から組織のマルチスケール・バイブレーショナル光学顕微鏡の創成 >
Tokushima University > Faculty of Engineering > Department of Mechanical Engineering > Mechanical Systems >
Tokushima University > Graduate School of Advanced Technology and Science > Intelligent Structures and Mechanics Systems Engineering > Mechanical Engineering > Mechanical Systems >
Tokushima University > Research Clusters > Research Clusters (Registered) > 1704034 高齢化社会に対応する「虚弱」の評価・治療モダリティーの創出 >
Tokushima University > Research Clusters > Research Clusters (Selected) > 1803001 要介護リスクを高める骨粗鬆症・関節リウマチにおける骨代謝制御機構とその破綻のエピゲノム解析 >
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Research Activity

Field of Study

Biomedical Engineering

Subject of Study

Biomedical engineering approach to understanding bone/microcirculation-related disorders

Book / Paper

Book:

1.Ji-Yean Kwon, Hisashi Naito, Takeshi Matsumoto and Masao Tanaka :
Apoptosis and medicine (Ntuli TM ed), --- Osteocyte Apoptosis-Induced Bone Resorption in Mechanical Remodeling Simulation - Computational Model for Trabecular Bone Structure ---,
InTech, 2012.
2.Masao Tanaka, Takeshi Matsumoto and Masahiro Todoh :
Biomechanics at Micro- and Nanoscale IV (Wada H ed), --- Microscopic Analysis of Bone ---,
World Scientific, 2007.
3.Takeshi Matsumoto, Masayuki Yoshino and Masao Tanaka :
Biomechanics at Micro- and Nanoscale Levels II (Wada H ed), --- Assessment of Cortical Bone Microstructure Using Monochromatic Synchrotron Radiation Micro-CT ---,
World Scientific, 2006.
4.Masao Tanaka, Takeshi Matsumoto, Masumi Ihara and Masahiro Todoh :
Biomechanics at Micro- and Nanoscale Levels I (Wada H ed), --- Note on Anisotropic Properties of Cancellous Bone and Trabeculae: Elasticity and Hardness ---,
World Scientific, 2005.
5.Takeshi Matsumoto and 望月 精一 :
化学工学 (酒井清孝 編), --- 第2章 流れ ---,
朝倉書店, Sep. 2005.
6.Takeshi Matsumoto :
冠循環のバイオメカニクス (梶谷文彦 編), --- 第4章3節 冠血流分布の不均一性 ---,
コロナ社, 2001.

Academic Paper (Judged Full Paper):

1.Toshihiro Sera, Hiroaki Kobayashi, Masato Hoshino, Kentaro Uesugi, Takeshi Matsumoto and Masao Tanaka :
The disuse effect on canal network structure and oxygen supply in the cortical bones of rats,
Biomechanics and Modeling in Mechanobiology, Vol.18, No.2, 375-385, 2018.
(DOI: 10.1007/s10237-018-1088-6,   PubMed: 30386958,   Elsevier: Scopus)
2.Toshihiro Sera, Yuya Iwai, Takaharu Yamazaki, Tetsuya Tomita, Hideki Yoshikawa, Hisashi Naito, Takeshi Matsumoto and Masao Tanaka :
Strain Measurements of the Tibial Insert of a Knee Prosthesis Using a Knee Motion Simulator,
Journal of Orthopaedics, Vol.14, No.4, 495-500, 2017.
(DOI: 10.1016/j.jor.2017.08.003,   PubMed: 28839353)
3.Takeshi Matsumoto and Daichi Goto :
Effect of Low-Intensity Whole-Body Vibration on Bone Defect Repair and Associated Vascularization in Mice,
Medical and Biological Engineering and Computing, Vol.55, 2257-2266, 2017.
(DOI: 10.1007/s11517-017-1664-4)
4.Ryosuke Higashi, Toshihiro Sera, Hisashi Naito, Takeshi Matsumoto and Masao Tanaka :
Pulmonary Kinematic Analysis With Non-Rigid Deformable Registration for Detecting Localised Emphysema,
Computer Methods in Biomechanics and Biomedical Engineering. Imaging & Visualization, Vol.5, No.2, 100-109, 2017.
(DOI: 10.1080/21681163.2015.1008649)
5.Toshihiro Sera, Ryosuke Higashi, Hisashi Naito, Takeshi Matsumoto and Masao Tanaka :
Distribution of Nanoparticle Depositions after a Single Breathing in a Murine Pulmonary Acinus Model,
International Journal of Heat and Mass Transfer, Vol.108, No.Part A, 730-739, 2017.
(DOI: 10.1016/j.ijheatmasstransfer.2016.12.057)
6.Takeshi Matsumoto, Shinya Itamochi and Yoshihiro Hashimoto :
Effect of Concurrent Use of Whole-Body Vibration and Parathyroid Hormone on Bone Structure and Material Properties of Ovariectomized Mice,
Calcified Tissue International, Vol.98, No.5, 520-529, 2016.
(DOI: 10.1007/s00223-015-0104-4,   PubMed: 26746476)
7.Takeshi Matsumoto, Daisuke Sato and Yoshihiro Hashimoto :
Individual and Combined Effects of Noise-Like Whole Body Vibration and Parathyroid Hormone Treatment on Bone Defect Repair in Ovariectomized Mice,
Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, Vol.230, No.1, 30-38, 2015.
(DOI: 10.1177/0954411915616987,   PubMed: 26586525,   Elsevier: Scopus)
8.橋本 佳洋 and Takeshi Matsumoto :
再生骨の骨質および力学特性に対する全身性微振動および断続的副甲状腺ホルモン(1-34)投与の相乗的作用の解析,
SPring-8/SACLA利用研究成果集, Vol.3, No.2, 380-384, 2015.
9.Takeshi Matsumoto and Shota Sato :
Stimulating Angiogenesis Mitigates the Unloading-Induced Reduction in Osteogenesis in Early-Stage Bone Repair in Rats,
Physiological Reports, Vol.3, No.3, e12335-1-e12335-12, 2015.
(DOI: 10.14814/phy2.12335,   PubMed: 25780087)
10.Yoshihiro Hashimoto, Shuichiro Fukushima, Takeshi Matsumoto, Hisashi Naito and Masao Tanaka :
Second Harmonic Generation Microscopy and Synchrotron Radiation CT for the Determination of Collagen and Mineral Deposition in Early-Stage Bone Repair: Effect of Whole Body Micro-Vibration,
Advanced Biomedical Engineering, Vol.3, 101-105, 2014.
(DOI: 10.14326/abe.3.101)
11.Takeshi Matsumoto, Daichi Goto and Shota Sato :
Subtraction Micro-Computed Tomography of Angiogenesis and Osteogenesis During Bone Repair Using Synchrotron Radiation With a Novel Contrast Agent,
Laboratory Investigation; a Journal of Technical Methods and Pathology, Vol.93, No.9, 1054-1063, 2013.
(DOI: 10.1038/labinvest.2013.87,   PubMed: 23835738,   Elsevier: Scopus)
12.Ji-Yean Kwon, Hisashi Naito, Takeshi Matsumoto and Masao Tanaka :
Estimation of Change of Bone Structures After Total Hip Replacement Using Bone Remodeling Simulation,
Clinical Biomechanics, Vol.28, No.5, 514-518, 2013.
(DOI: 10.1016/j.clinbiomech.2013.04.003,   PubMed: 23647807,   Elsevier: Scopus)
13.權志 妍, 内藤 尚, 音丸 格, 高尾 正樹, 佐藤 嘉伸, 菅野 伸彦, 富山 憲幸, Takeshi Matsumoto and 田中 正夫 :
人工股関節手術計画における力学的評価指標 -メカノスタット理論/リモデリングシミュレーションからの検討-,
日本臨床バイオメカニクス会誌, Vol.33, 265-269, 2012.
14.Takeshi Matsumoto, Shuichiro Fukushima, Takeshi Kanasaki and Shingo Hagino :
Relationship Between Aortic Mineral Elements and Osteodystrophy in Mice With Chronic Kidney Disease,
Biological Trace Element Research, Vol.150, No.1-3, 278-284, 2012.
(DOI: 10.1007/s12011-012-9466-x,   PubMed: 22700181)
15.Hisashi Naito, Yasushi Akazawa, Ayu Miura, Takeshi Matsumoto and Masao Tanaka :
Identification of Individual Muscle Length Parameters From Measurements of Passive Joint Moment Around the Ankle Joint,
Journal of Biomechanical Science and Engineering, Vol.7, 168-176, 2012.
(DOI: 10.1299/jbse.7.168,   Elsevier: Scopus)
16.Takako Osawa, Takeshi Matsumoto, Hisashi Naito and Masao Tanaka :
Evaluation of Viscoelastic Property of Articular Cartilage Based on Mechanical Model Considering Tissue Microstructure,
Journal of Biomechanical Science and Engineering, Vol.7, No.1, 31-42, 2012.
(DOI: 10.1299/jbse.7.31,   Elsevier: Scopus)
17.Takeshi Matsumoto, Takushi Miyakawa and Daiki Yamamoto :
Effects of Vitamin K on the Morphometrical and Material Properties of Bone in The Tibiae of Growing Rats,
Metabolism: Clinical and Experimental, Vol.61, No.3, 407-414, 2011.
(DOI: 10.1016/j.metabol.2011.07.018,   PubMed: 21944271)

Review, Commentary:

1.Takeshi Matsumoto :
放射光CTによる皮質骨ポア構造解析,
日本臨牀増刊号: 最新の骨粗鬆症学, 63-67, Apr. 2013.

Proceeding of International Conference:

1.Takeshi Matsumoto and Kawahito Yuya :
Bone-Anabolic Action of Low-Intensity Whole-Body Vibration and the Involvement of Bone Vascularization in Juvenile Mic,
IUPESM 2018 Book of Abstracts, 569-570, Praha, Jun. 2018.
2.Shinya Itamochi and Takeshi Matsumoto :
Combined Effect of Whole-body Vibration and Parathyroid Hormone on Bone Structure and Material Properties of Ovariectomized Mice,
Physiology 2016 Abstracts, 356-357, Dublin, Jul. 2016.
3.Takeshi Matsumoto and Shinya Itamochi :
Effects of Whole Body Vibration on Breast Cancer Bone Metastasis and Vascularization in Mice,
Physiology 2016 Abstracts, 166, Dublin, Jul. 2016.
4.Takeshi Matsumoto, Shinya Itamochi and Shota Sato :
Bone and Microvascular Imaging by K-edge Subtraction µCT Using Synchrotron Lights With Zirconia Contrast Medium,
Proc.10th World Cong. Microcirc., 76, Kyoto, Sep. 2015.
5.Takako Osawa, Takeshi Matsumoto, Hisashi Naito and Masao Tanaka :
Tissue/Material Properties of Enzymatically-Degenerated Articular Cartilage Evaluated by Using Viscoelastic Model Considering Depth-Dependent Microstructure,
Pro. 11th World Cong. Comput. Mech., a3543-1-a3543-2, Barcelona, Jul. 2015.
6.Hiroshi Kobayashi, Toshihiro Sera, Takeshi Matsumoto and Masao Tanaka :
Computational Analysis of Physiological Substance Concentration in Cortical Bone Considering Lacunar-Canalicular Network,
Pro. 1st Global Conf. Biomed. Eng., OB32-1-OB32-2, Tainan, Oct. 2014.
7.Yoshihiro Hashimoto, Takeshi Matsumoto and Masao Tanaka :
Synergetic Effect of Whole-Body Vibration and Parathyroid Hormone (1-34) on Regenerated Bone Quality During Defect Healing,
Pro. 1st Global Conf. Biomed. Eng., OA22-1-OA22-3, Tainan, Oct. 2014.
8.Takeshi Matsumoto, Shota Sato and Daichi Goto :
Whole-body Vibration With Extremely Low-Aamplitude Accelerates Early-Stage Bone Defect Healing With Reducing Angiogenesis,
Proc. European Calcified Tissue Society Congress 2014, 49, Praha, May 2014.
9.Shota Sato, Takeshi Matsumoto, Hisashi Naito and Masao Tanaka :
Involvement of Angiogenesis in Early-Stage Bone Repair,
Proc. 35th Ann. Int. Conf. IEEE Eng. Med. Biol., a3238-1, Osaka, Jul. 2013.
10.Takeshi Matsumoto, Shota Sato and Daichi Goto :
Deferoxamine Alleviates Unloading-Induced Delay of Bone Defect Repair,
Proc. 2nd Joint Meeting of IBMS and JSBMR (IBMS BoneKEy 10), S43, Kobe, Jun. 2013.
11.Takeshi Matsumoto :
Quantitative Bone CT Using Synchrotron Source,
Proc. 2013 Spring Meeting of KSME Bioeng. Div., 1, Yeosu, May 2013.
12.Takaki Nakayama, Hisashi Naito, Takeshi Matsumoto and Masao Tanaka :
Optimal Cornea Shape Design Problem for Corneal Refractive Surgery,
Proc. 10th World Cong. Struct. Multidiscip. Optim., 1-7, Orlando, May 2013.
13.Takeshi Matsumoto, Sato Shota and Goto Daichi :
Hypoxia-Inducible Factor-Mediated Enhancement of Angiogenesis Reduces the delay of bone defect healing caused by mechanical unloading,
Physiology 2012, 234, Edinburgh, Jul. 2012.
14.Kwon Jiyean, Naito Hisashi, Takeshi Matsumoto, Otomal Itaru, Takao Masaki, Sato Yoshinobu, Sugano Nobuhiko and Tanaka Masao :
Simulation Study of Bone Loss After Total Hip Replacement,
Journal of Biomechanics, Vol.45, No.S1, S110, Lisbon, Jul. 2012.

Proceeding of Domestic Conference:

1.Shusaku Kawano, Tomoaki Takeda and Takeshi Matsumoto :
X線位相差CTによる関節軟骨のダイナミック3Dイメージング,
IEICE Technical Report, Vol.119, No.137, 39-41, Jul. 2019.
2.Yuta Kameyama, Yosuke Iki, Takeshi Matsumoto, Takeo Minamikawa, Takeshi Yasui and Katsuya SATO :
Influence of intermittent vibration stimuli on osteoblasts matrix production,
第30回バイオフロンティア講演会講演論文集, 2A31, Jul. 2019.
3.Keishi Hashimoto and Takeshi Matsumoto :
骨粗鬆症マウスの骨欠損修復における断続性微振動刺激の効果,
日本機械学会中国四国支部第57期総会・講演会講演論文集, 108, Mar. 2019.
4.Yuya Kawahito and Takeshi Matsumoto :
微振動刺激による骨粗鬆症抑制効果と骨微小循環構築の関与:休止期挿入による影響について,
日本機械学会中国四国支部第57期総会・講演会講演論文集, 107, Mar. 2019.
5.Takako Osawa, Masato Hoshino and Takeshi Matsumoto :
Dynamic phase contrast X-ray CT of articular cartilage under repetitive compression,
第31回バイオエンジニアリング講演会論文集, 1E24, Dec. 2018.
6.Keishi Hashimoto and Takeshi Matsumoto :
Whole-body vibration with irregular rest interval promotes bone defect healing in ovariectomized mice,
第31回バイオエンジニアリング講演会論文集, 1B15, Dec. 2018.
7.Katsuya SATO, Shota Okazawa, Yuta Kameyama, Takeshi Matsumoto, Takeo Minamikawa and Takeshi Yasui :
Enhancement of osteoblastic matrix synthesis by using mechanical vibration stimuli,
第31回バイオエンジニアリング講演会論文集, 1F31, Dec. 2018.
8.Yuta Kameyama, Takeshi Matsumoto, Takeo Minamikawa, Takeshi Yasui and Katsuya SATO :
Investigation of vibration condition to enhance osteoblasts proliferation and matrix mineralization,
第29回バイオフロンティア講演会論文集, 1A21, Oct. 2018.
9.Keishi Hashimoto and Takeshi Matsumoto :
Effects of rest insertion combined with whole-body vibration on bone healing in ovariectomized mice,
第57回日本生体医工学会大会抄録集, 489, Jun. 2018.
10.Yuya Kawahito and Takeshi Matsumoto :
Bone-anabolic action of low-intensity vibratory stimulation and the involvement of bone microvascularity,
第30回バイオエンジニアリング講演会・講演論文集, 264, Dec. 2017.
11.Takeshi Matsumoto :
骨リモデリング・再生における微振動刺激作用の検証,
第44回日本臨床バイオメカニクス学会・抄録集, 87, Nov. 2017.
12.宇治田 俊樹 and Takeshi Matsumoto :
がん骨転移における微振動刺激の作用関す実験的検証,
第28回バイオフロンティア講演会・講演論文集 USB, C15, Oct. 2017.
13.川人 侑弥 and Takeshi Matsumoto :
Bone anabolic effect of low-intensity vibratory stimulation and the involvement of bone micro-vasculature,
第28回バイオフロンティア講演会・講演論文集 USB, C14, Oct. 2017.
14.川人 侑弥 and Takeshi Matsumoto :
全身性微振動刺激が骨および骨微小血管分布に及ぼす影響 :放射光CT による検討,
JBMES2017 Proceedings, 114, Sep. 2017.
15.Okazawa Shota, Takeshi Matsumoto, Takeshi Yasui, Takeo Minamikawa and Katsuya SATO :
骨芽細胞のコラーゲン産生における振動・ストレッチ複合刺激の影響,
日本機械学会2017年年次大会, S0210201, Sep. 2017.
16.清水 亮汰 and Takeshi Matsumoto :
Monitoring of bone repair process by in-line phase-contrast CT: evaluation of osteoporotic bone repair in mice,
第56回日本生体医工学会大会抄録集, 324, May 2017.
17.Ryota Shimizu and Takeshi Matsumoto :
放射光位相CTに基づく⾻構造ダイナミクスのインビボイメージング:マウス骨欠損モデルへの応用,
日本機械学会中国四国支部第55期総会・講演会講演論文集, Mar. 2017.
18.Yuya Kawahito and Takeshi Matsumoto :
全身性微振動刺激による骨構造への影響と骨微小血管形成の関与,
日本機械学会中国四国支部第55期総会・講演会講演論文集, Mar. 2017.
19.Shota Okazawa, Takeshi Matsumoto, Takeshi Yasui, Takeo Minamikawa and Katsuya SATO :
Enhancement of osteoblastic collagen synthesis under combined vibration and stretching stimulation,
日本機械学会中国四国支部第55期総会・講演会講演論文集, Feb. 2017.
20.清水 亮太 and Takeshi Matsumoto :
骨粗鬆症における骨修復遅延およびepoxyeeicosatrienoic acid による骨修復改善効果の解析:放射光位相CTによる検討,
第39回日本生体医工学会中国四国支部大会・講演抄録, 14, Oct. 2016.
21.宇治田 俊樹 and Takeshi Matsumoto :
がん骨破壊に対する全身性微振動刺激の作用について:インビボ位相 CT に基づく検討,
JBMES2016 Proceedings, 57, Sep. 2016.
22.板持 伸弥, Takeshi Matsumoto and 田中 正夫 :
がん骨破壊に対する全身性高周波微振動負荷の抑制作用の検討,
日本機械学会関西支部第91期総会・講演会講演論文集, 355, Mar. 2016.
23.板持 伸弥, Takeshi Matsumoto and 田中 正夫 :
骨粗鬆症マウスモデルに対する全身性微振動負荷および副甲状腺ホルモン投与の併用効果の検証,
第54回日本生体医工学会大会抄録集, 255, May 2015.

Et cetera, Workshop:

1.Takeshi Matsumoto :
骨形態・機能のマイクロスコピック解析,
日本生体医工学会専門別研究会・第158回バイオメカニクス研究会, Jan. 2016.

Report:

1.Takeshi Matsumoto :
骨粗鬆症患者の骨折治療を目的とした全身性ランダム様微振動の骨修復促進に関する実験的研究,
医科学応用研究財団研究報告, Vol.36, 134-138, 2018.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • バイオソフトマテリアルの動的局所変形を捉える放射光位相差ダイナミックCTの確立 (Project/Area Number: 18K19926 )
  • 顎顔面領域骨代謝性疾患におけるエピゲノム制御による新規骨リモデリング機構の解明 (Project/Area Number: 18H03011 )
  • Experimental study on preventive effect of whole body vibration on metastatic progression of breast cancer to bone (Project/Area Number: 15K12509 )
  • Effects of whole body vibration on cancer-induced bone destruction (Project/Area Number: 26282120 )
  • Effectiveness of noise-like vibration loading in preventing osteoporosis (Project/Area Number: 24650265 )
  • Experiment research on the therapeutic impact of low-magnitude vibrations on eraly-stage bone healing (Project/Area Number: 23300165 )
  • Inhibitory effect of vitamin K2 on vascular calcification and osteoporosis : experimental approach to understanding the bone-vascular axis (Project/Area Number: 21650112 )
  • Experimental research on the development of a new therapy for bone injury via sympathetic nerve system (Project/Area Number: 20300158 )
  • 発育期の骨質強化に対する力学的負荷およびビタミンK摂取の有効性に関する実験的研究 (Project/Area Number: 19650116 )
  • 単色放射光CTによる骨内局所潅流および骨微細構造の同時評価法の開発 (Project/Area Number: 17650138 )
  • Study on the angiogenesis-mediated promotion of bone fracture healing using repeated stimuli induced by microbubble destruction (Project/Area Number: 17300152 )
  • Development of the imaging system to evaluate of blood flow distribution and metabolic activity in myocardial microcirculation. (Project/Area Number: 15300174 )
  • Analysis and modeling of micro- or nano-scale structure and microcirculation of bone (Project/Area Number: 15086210 )
  • リアルタイムグラメトリシステムの開発と8GeV放射光心筋微小血管造影への応用 (Project/Area Number: 14658298 )
  • 細胞表面および細胞内部への応力負荷に対する内皮細胞内情報伝達メカニズムの解析 (Project/Area Number: 14658297 )
  • Evaluation of dynamic changes of nitric oxide and oxidative stress in hemodialysis patients (Project/Area Number: 13680961 )
  • Analysis of cardiac lymphatic dynamics in beating canine hearts using a high-speed CCD microscope (Project/Area Number: 13670773 )
  • Analysis of cardiac lymphatic dynamics in beating canine hearts using a high-speed CCD microscope (Project/Area Number: 13670772 )
  • Functional Morphology of Coronary Arteriol.es in Relation to Coronary Microcirculatory Disturbance by Micro-imaging Techniques (Project/Area Number: 12670714 )
  • Development of Pencil-type CCD Microscope for evaluating of renal glomerular microcirculation with normal and hypertensive Rat (Project/Area Number: 12557065 )
  • SPring8放射光を用いた重元素ステレオ造影による心筋微小血管ダイナミクス解析 (Project/Area Number: 12480269 )
  • ダブル分子血流トレーサを利用した冠細動脈塞栓後の心筋微小循環異常の経時的計測 (Project/Area Number: 11770388 )
  • Analysis of abnormal coronary micro-circulation in a diabetic or hypertensive rat heart by simultaneous measurement of NADH fluorescence and blood flow distribution (Project/Area Number: 11680856 )
  • Endothelium-dependent and -independent responses of coronary arteriole to pulsatile mechanical stress in vivo (Project/Area Number: 10670694 )
  • Analysis on local blood flow, metabolic NADH distribution and micro-mechanical dysfunction during ischaemia of coronary micro-circulation (Project/Area Number: 10670686 )
  • Analysis on myocardial ischemia by observation of NADH fluorescence/oxygen partial pressure phosphorescence using an intra-vital needle microscope (Project/Area Number: 10558140 )
  • Evaluation of the interaction between myogenic response and endothelium-derived factor by a microvessel perfusion system (Project/Area Number: 10555292 )
  • 血管内皮由来一酸化窒素を介する大動脈内バルーンパンピングの冠循環改善効果の評価 (Project/Area Number: 09770925 )
  • Analysis of vasodilated effect of nitroglycerin on microvessels us ing a high speed CCD microscope (Project/Area Number: 09670775 )
  • Analysis on intramyocardial microcirculation by a high-speed CCD intravitalmicroscope with a visual servo manipulator (Project/Area Number: 09558125 )
  • Three-dimensional imaging of myocardial blood flow with microcomputed (Project/Area Number: 09555133 )
  • 虚血・再潅流後の心筋微小循環heterogeneityの病態生理学的意義について (Project/Area Number: 08770541 )
  • Evaluation of Subendocardial Microcirculatory Hemodynamics by High-Speed Needle-Probe CCD Microscope (Project/Area Number: 08558103 )
  • Development of 3-D Evaluation System of Microheterogeneity of Intramyocardial Flow Using Molecular Flow Tracers (Project/Area Number: 08557051 )
  • Development of Measuring System of Endothelium-Derived Relaxing Factor(NO)and Vascular Luminal Shear Stress (Project/Area Number: 08555207 )
  • 分子血流トレーサを用いた冠微小循環調節系の時間的応答の解明 (Project/Area Number: 07780794 )
  • Analysis of vasodilated effect of nitroglycerin on microvessels (Project/Area Number: 07670828 )
  • Evaluation of Coronary Vasoregulation Through Controlling Regional Myocardial Flow (Project/Area Number: 07558134 )
  • Computational fluiddynamical analysis of correlations between blood flow and LDL at the vascular location where atherosclerosis occurs preferentially (Project/Area Number: 06680868 )
  • Developement of side-on typed needle-probe for CCD microscope (Project/Area Number: 06558130 )
  • Time-serial analysis of position of LDL and infiltration of monocyte in vascular wall by laser scanning confocal microscope (Project/Area Number: 06558129 )
  • Evaluation of myocardial blood flow heterogeneity by using molecular deposition technique and fractal analysis (Project/Area Number: 05680768 )
  • Development of Micro-Probe for Continuous Sampling of Interstitial Fluid in Myocardium for Evaluation of Physiological Circulation, Control, and Mass Transport. (Project/Area Number: 05558119 )
  • A High Resolution CCD Intravital Fluorescent Microscope for Observation of Coronary Smaller Microvessels in a Beating Heart (Project/Area Number: 05557043 )
  • Analysis of Coronary Slosh Phenomenon by Needle-probe CCD Microscope and Molecular Blood Flow Tracer (Project/Area Number: 05454278 )
  • 血流の流体力学的構造と血管内皮細胞の立体的形状の相互関連性の解析 (Project/Area Number: 05221239 )
  • Study on the subendocardial ischemia using a high resolution needle-probe video-microscope with a CCD camera (Project/Area Number: 04670569 )
  • 血管内皮配列と微細形態観察のための冠血管鋳型・レーザースキャン顕微鏡解析法の開発 (Project/Area Number: 04557043 )
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