Tokushima University / Educator and Researcher Directory --- Minamikawa, Takeo

Personal Web Page

http://femto.me.tokushima-u.ac.jp/member/minamikawa/

https://researchmap.jp/takeominamikawa (researchmap)

https://orcid.org/0000-0003-3528-7163 (ORCID)

Field of Study

○	Raman spectroscopy
○	Biomedical Engineering
○	Applied Optics
○	Spectoscopic Measurement

Subject of Study

○	Raman spectroscopy and microscopy
○	Medical application of Raman spectroscopy
○	Applied instrumentation of optical frequency comb
○	Restorational study of cultural property by optical instrumentation

Book / Paper

Book:

1.	Takeo Minamikawa : ラマン分光スペクトル解釈事例集, Technical Information Institute Co., Ltd., Tokyo, Feb. 2022.
2.	Takeo Minamikawa : 深紫外LEDを用いた新型コロナウイルス不活化, 光産業技術振興協会, 2022.
3.	Takeo Minamikawa and Tetsuro Takamatsu : Raman microspectroscopy, 朝倉書店, Tokyo, Jan. 2018.
4.	Takeo Minamikawa, Yoshinori Harada and Tetsuro Takamatsu : Photodynamic detection of lymph node metastases in gastrointestinal cancer by using 5-aminolevulinic acid, Springer International Publishing, Switzerland, Aug. 2015.

Academic Paper (Judged Full Paper):

1.	Katsuya SATO, Takeo Minamikawa and Takeshi Yasui : Raman Spectroscopic Evaluation of Composition of Matrix Synthesized by Osteoblasts under Microvibration Stimulation, Advanced Biomedical Engineering, Vol.13, 11-18, 2024. (Link to Publication Site) ● Publication site (DOI): 10.14326/abe.13.11 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.14326/abe.13.11 (DOI: 10.14326/abe.13.11)
2.	Saya Matsuzaki, Eiji Hase, Hiroki Takanari, Yuri Hayashi, Yusaku Hayashi, Haruto Oshikata, Takeo Minamikawa, Satoko Kimura, Mayuko Ichimura-Shimizu, Takeshi Yasui, Masafumi Harada and Koichi Tsuneyama : Quantification of collagen fiber properties in alcoholic liver fibrosis using polarization-resolved second harmonic generation microscopy., Scientific reports, Vol.13, No.1, 2023. (Summary) Liver fibrosis is assessed mainly by conventional staining or second harmonic generation (SHG) microscopy, which can only provide collagen content in fibrotic area. We propose to use polarization-resolved SHG (PR-SHG) microscopy to quantify liver fibrosis in terms of collagen fiber orientation and crystallization. Liver samples obtained from autopsy cases with fibrosis stage of F0-F4 were evaluated with an SHG microscope, and 12 consecutive PR-SHG images were acquired while changing the polarization azimuth angle of the irradiated laser from 0° to 165° in 15° increments using polarizer. The fiber orientation angle (φ) and degree (ρ) of collagen were estimated from the images. The SHG-positive area increased as the fibrosis stage progressed, which was well consistent with Sirius Red staining. The value of φ was random regardless of fibrosis stage. The mean value of ρ (ρ-mean), which represents collagen fiber crystallinity, varied more as fibrosis progressed to stage F3, and converged to a significantly higher value in F4 than in other stages. Spatial dispersion of ρ (ρ-entropy) also showed increased variation in the stage F3 and decreased variation in the stage F4. It was shown that PR-SHG could provide new information on the properties of collagen fibers in human liver fibrosis. (Keyword) Humans / Second Harmonic Generation Microscopy / Collagen / Liver Cirrhosis / Refraction, Ocular / Coloring Agents (Link to Publication Site) ● Publication site (DOI): 10.1038/s41598-023-48887-8 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38092851 ● Search Scopus @ Elsevier (PMID): 38092851 ● Search Scopus @ Elsevier (DOI): 10.1038/s41598-023-48887-8 (DOI: 10.1038/s41598-023-48887-8, PubMed: 38092851)
3.	Eiji Hase, Yu Tokizane, Kazuki Sadahiro, Takeo Minamikawa, Isao Morohashi and Takeshi Yasui : Nanometer-precision surface metrology of millimeter-sized stepped objects using full-cascade-linked synthetic-wavelength digital holography using a line-by-line full-mode-extracted optical frequency comb, Optics Express, Vol.31, No.11, 18088-18097, 2023. (Summary) Digital holography (DH) is a powerful tool for the surface profilometry of objects with sub-wavelength precision. In this article, we demonstrate full-cascade-linked synthetic-wavelength DH for nanometer-precision surface metrology of millimeter-sized stepped objects. 300 modes of optical frequency comb (OFC) with different wavelengths are sequentially extracted at a step of mode spacing from a 10GHz-spacing, 3.72THz-spanning electro-optic modulator OFC. The resulting 299 synthetic wavelengths and a single optical wavelength are used to generate a fine-step wide-range cascade link covering within a wavelength range of 1.54 µm to 29.7 mm. We determine the sub-millimeter and millimeter step differences with axial uncertainty of 6.1 nm within the maximum axial range of 14.85 mm. (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.483408 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37381527 ● Search Scopus @ Elsevier (PMID): 37381527 ● Search Scopus @ Elsevier (DOI): 10.1364/OE.483408 (DOI: 10.1364/OE.483408, PubMed: 37381527)
4.	Yu Tokizane, Shota Okada, Kenji Nishimoto, Yasuhiro Okamura, Hiroki Kishikawa, Takeo Minamikawa, Eiji Hase, Junichi Fujikata, Masanobu Haraguchi, Atsushi Kanno, Shintaro Hisatake, Naoya Kuse and Takeshi Yasui : Terahertz wireless communication in a 560-GHz band using a Kerr micro-resonator soliton comb, Optics Continuum, Vol.2, No.5, 1267-1275, 2023. (Tokushima University Institutional Repository) ● Metadata: 118500 (Link to Publication Site) ● Publication site (DOI): 10.1364/OPTCON.491729 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1364/OPTCON.491729 (Tokushima University Institutional Repository: 118500, DOI: 10.1364/OPTCON.491729)
5.	Yuko Miyakami, Takeo Minamikawa, Hirohisa Ogawa, Mayuko Shimizu and Koichi Tsuneyama : Definitive Confirmation of Erythropoietic Protoporphyria via Re-biopsy Three Years After Initial Liver Biopsy at Age 15., Curēus, Vol.15, No.4, e38017, 2023. (Summary) Erythropoietic protoporphyria (EPP) is a rare inherited disorder of porphyrin metabolism that can cause liver damage and cholestatic hepatocellular failure. We report a case of EPP in a teenaged male who underwent liver biopsy for investigation of liver dysfunction of unknown cause. The diagnosis was not made until a re-biopsy approximately three years later, when the patient presented with recurrent skin lesions and elevated blood and urinary protoporphyrin levels. The liver biopsies contained brownish deposits that exhibited birefringence under polarized light and porphyrin fluorescence under fluorescence spectroscopy. EPP should be considered in young patients with unexplained liver dysfunction, skin symptoms, and seasonal changes in symptoms. Fluorescence spectroscopy of liver biopsy tissue can be a useful tool in the diagnosis of EPP. (Link to Publication Site) ● Publication site (DOI): 10.7759/cureus.38017 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 37228562 ● Search Scopus @ Elsevier (PMID): 37228562 ● Search Scopus @ Elsevier (DOI): 10.7759/cureus.38017 (DOI: 10.7759/cureus.38017, PubMed: 37228562)
6.	Qingyi Lin, Mutsumi Aihara, Akihiro Shirai, Ami Tanaka, Koki Takebayashi, Naoaki Yoshimura, Nanaka Torigoe, Megumi Nagahara, Takeo Minamikawa and Takeshige Otoi : Porcine embryo development and inactivation of microorganisms after ultraviolet-C irradiation at 228 nm, Theriogenology, Vol.197, 252-258, 2023. (Summary) It is important to prevent contamination inside the incubator as a method of preventing microbial infections during the embryo culture. In the present study, we examined the effects of ultraviolet-C (UV-C) irradiation, used for microorganism inactivation, on embryo development and the growth of bacteria, including Escherichia coli and Staphylococcus aureus, and the fungus Cladosporium cladosporioides. In the embryo irradiation experiment, we examined the effects of the plastic lid of the culture dish, irradiation distances (10, 20, and 25 cm), and different irradiation wavelengths (228 and 260 nm) during embryo culture for 7 days on the development and quality of porcine in vitro-fertilized embryos. None of the embryos cultured in dishes without plastic lids developed into blastocysts after irradiation with 228 nm UV-C. When porcine embryos were cultured in a culture dish with lids, the 228 nm UV-C irradiation decreased blastocyst formation rates of the embryos but not their quality, irrespective of the UV-C irradiation distance. Moreover, irradiation with 260 nm UV-C, even with plastic lids, had more detrimental effects on embryo development than irradiation with 228 nm UV-C. Investigation of the inactivating effects of UV-C irradiation at 228 nm and 260 nm on the growth of the bacteria and fungus showed that 260 nm UV-C reduced the viability to a greater extent than 228 nm UV-C. Moreover, the disinfection efficacy for the bacteria increased when the irradiation duration increased and the distance decreased. In conclusion, porcine embryos can develop into blastocysts without loss of quality even after continuous long-duration irradiation (7 days) with 228 nm UV-C, which can inactivate the growth of bacteria and the tested fungus; however, the development rate of the embryo is reduced. (Keyword) Animals / Swine / Embryonic Development / Blastocyst / Embryo, Mammalian / Fertilization in Vitro / Escherichia coli / Bacteria / Ultraviolet Rays (Link to Publication Site) ● Publication site (DOI): 10.1016/j.theriogenology.2022.12.015 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36525864 ● Search Scopus @ Elsevier (PMID): 36525864 ● Search Scopus @ Elsevier (DOI): 10.1016/j.theriogenology.2022.12.015 (DOI: 10.1016/j.theriogenology.2022.12.015, PubMed: 36525864)
7.	Takaaki Koma, Naoya Doi, Akihiro Suzuki, Kentaro Nagamatsu, Takeshi Yasui, Koji Yasutomo, Akio Adachi, Takeo Minamikawa and Masako Nomaguchi : Major target for UV-induced complete loss of HIV-1 infectivity: A model study of single-stranded RNA enveloped viruses, Frontiers in Virology, Vol.2, 994842, 2022. (Link to Publication Site) ● Publication site (DOI): 10.3389/fviro.2022.994842 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.3389/fviro.2022.994842 (DOI: 10.3389/fviro.2022.994842)
8.	Ryo Kato, Taka-aki Yano, Takeo Minamikawa and Takuo Tanaka : High-sensitivity hyperspectral vibrational imaging of heart tissues by mid-infrared photothermal microscopy, Analytical Sciences, Vol.38, No.12, 1497-1503, 2022. (Summary) Visualizing the spatial distribution of chemical compositions in biological tissues is of great importance to study fundamental biological processes and origin of diseases. Raman microscopy, one of the label-free vibrational imaging techniques, has been employed for chemical characterization of tissues. However, the low sensitivity of Raman spectroscopy often requires a long acquisition time of Raman measurement or a high laser power, or both, which prevents one from investigating large-area tissues in a nondestructive manner. In this work, we demonstrated chemical imaging of heart tissues using mid-infrared photothermal (MIP) microscopy that simultaneously achieves the high sensitivity benefited from IR absorption of molecules and the high spatial resolution down to a few micrometers. We successfully visualized the distributions of different biomolecules, including proteins, phosphate-including proteins, and lipids/carbohydrates/amino acids. Further, we experimentally compared MIP microscopy with Raman microscopy to evaluate the sensitivity and photodamage to tissues. We proved that MIP microscopy is a highly sensitive technique for obtaining vibrational information of molecules in a broad fingerprint region, thereby it could be employed for biological and diagnostic applications, such as live-tissue imaging. (Keyword) Microscopy / Spectrum Analysis, Raman / Vibration / Proteins / Lasers (Link to Publication Site) ● Publication site (DOI): 10.1007/s44211-022-00182-8 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 36070070 ● Search Scopus @ Elsevier (PMID): 36070070 ● Search Scopus @ Elsevier (DOI): 10.1007/s44211-022-00182-8 (DOI: 10.1007/s44211-022-00182-8, PubMed: 36070070)
9.	Mayuko Shimizu, Soichiroh Ishimaru, Wai Yee Yan Christine, Takeo Minamikawa, Takaaki Tsunematsu, Aiko Endoh, Takumi Kojima, Minoru Matsumoto, Tomoko Kobayashi, Satoshi Sumida, Takumi Kakimoto, MIYAGAMI Yuko, Hirohisa Ogawa, Takeshi Oya and Koichi Tsuneyama : Establishment of an epicutaneously sensitized murine model of shellfish allergy and evaluation of skin condition by Raman microscopy., Applied Sciences, Vol.12, No.3566, 2022. (Tokushima University Institutional Repository) ● Metadata: 117211 (Link to Publication Site) ● Publication site (DOI): 10.3390/app12073566 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.3390/app12073566 (Tokushima University Institutional Repository: 117211, DOI: 10.3390/app12073566)
10.	Takeo Minamikawa, Eiji Hase, Mayuko Shimizu, Yuki Morimoto, Akihiro Suzuki, Takeshi Yasui, Satoko Nakamura, Akemi Tsutsui, Koichi Takaguchi and Koichi Tsuneyama : Assessment of Ultra-Early-Stage Liver Fibrosis in Human Non-Alcoholic Fatty Liver Disease by Second-Harmonic Generation Microscopy., International Journal of Molecular Sciences, Vol.23, No.6, 3357, 2022. (Summary) Non-alcoholic fatty liver disease (NAFLD) is associated with the chronic progression of fibrosis. In general, the progression of liver fibrosis is determined by a histopathological assessment with a collagen-stained section; however, the ultra-early stage of liver fibrosis is challenging to identify because of the low sensitivity in the collagen-selective staining method. In the present study, we demonstrate the feasibility of second-harmonic generation (SHG) microscopy in the histopathological diagnosis of the liver of NAFLD patients for the quantitative assessment of the ultra-early stage of fibrosis. We investigated four representative NAFLD patients with early stages of fibrosis. SHG microscopy visualised well-matured fibrotic structures and early fibrosis diffusely involving liver tissues, whereas early fibrosis is challenging to be identified by conventional histopathological methods. Furthermore, the SHG emission directionality analysis revealed the maturation of each collagen fibre of each patient. As a result, SHG microscopy is feasible for assessing liver fibrosis on NAFLD patients, including the ultra-early stage of liver fibrosis that is difficult to diagnose by the conventional histopathological method. The assessment method of the ultra-early fibrosis by using SHG microscopy may serve as a crucial means for pathological, clinical, and prognostic diagnosis of NAFLD patients. (Keyword) Biopsy / Collagen / Fibrosis / Humans / Liver / Liver Cirrhosis / Non-alcoholic Fatty Liver Disease / Second Harmonic Generation Microscopy (Tokushima University Institutional Repository) ● Metadata: 117221 (Link to Publication Site) ● Publication site (DOI): 10.3390/ijms23063357 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35328778 ● Summary page in Scopus @ Elsevier: 2-s2.0-85126575411 (Tokushima University Institutional Repository: 117221, DOI: 10.3390/ijms23063357, PubMed: 35328778, Elsevier: Scopus)
11.	Hidenori Koresawa, Kohta Seki, Eiji Hase, Yu Tokizane, Takeo Minamikawa, Taka-aki Yano, Taira Kajisa and Takeshi Yasui : Beam-angle-scanning surface plasmon resonance sensor for rapid, high-precision sensing of refractive index and bio-molecules, Optics Continuum, Vol.1, No.3, 565-574, 2022. (Link to Publication Site) ● Publication site (DOI): 10.1364/OPTCON.451947 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1364/OPTCON.451947 (DOI: 10.1364/OPTCON.451947)
12.	Yu Tokizane, Takayoshi Yamaguchi, Takeo Minamikawa, Eiji Hase, Kenzo Yamaguchi, Akihiro Suzuki, Takao Ueda and Takeshi Yasui : Ultralow-frequency ultranarrow-bandwidth coherent terahertz imaging for nondestructive testing of mortar material, Optics Express, Vol.30, No.3, 4392-4401, 2022. (Summary) Nondestructive testing of concrete materials is essential in civil engineering to maintain social infrastructure such as buildings or bridges. In this study, we constructed an ultralow-frequency, ultranarrow-bandwidth, coherent terahertz (THz) imaging system based on THz time-domain spectroscopy (THz-TDS). Based on its ultralow-frequency-localized THz wave and coherent detection, the present system achieved a wide dynamic range of THz power over 100 dB at 0.046 THz, which is appropriate to measure the mortar material. The achieved dynamic range of the THz power was 59 dB larger than that of a commercialized THz-TDS system and 49 dB larger than that of an ultralow-frequency noncoherent THz imaging system equipped with a high-power electric THz source. Ultimately, the proposed system could visualize the inner structure of a mortar sample with a thickness of 10 mm, and the present system can investigate a mortar sample with a thickness of over 130 mm. The proposed method is an attractive tool for non-destructive testing of thick concrete structures characterized by non-invasiveness and non-contact remoteness. (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.449092 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35209677 ● Search Scopus @ Elsevier (PMID): 35209677 ● Search Scopus @ Elsevier (DOI): 10.1364/OE.449092 (DOI: 10.1364/OE.449092, PubMed: 35209677)
13.	Masatomo Beika, Yoshinori Harada, Takeo Minamikawa, Yoshihisa Yamaoka, Noriaki Koizumi, Yasutoshi Murayama, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Eigo Otsuji, Tetsuro Takamatsu and Hideo Tanaka : Accumulation of Uroporphyrin I in Necrotic Tissues of Squamous Cell Carcinoma after Administration of 5-Aminolevulinic Acid, International Journal of Molecular Sciences, Vol.22, No.18, 10121, 2021. (Tokushima University Institutional Repository) ● Metadata: 116740 (Link to Publication Site) ● Publication site (DOI): 10.3390/ijms221810121 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85115068944 (Tokushima University Institutional Repository: 116740, DOI: 10.3390/ijms221810121, Elsevier: Scopus)
14.	Keita Hoshi, Kazuma Kusumoto, Airi Matsumoto, Atsushi Tabata, Hideaki Nagamune, Eiji Hase, Takeo Minamikawa, Takeshi Yasui, Yasushi Yoshida, Keiji Minagawa, Yasushi Imada and Fumitoshi Yagishita : Synthesis of D-π-A type benzothiazolepyridinium salt composite and its application as photo-degradation agent for amyloid fibrils, Bioorganic & Medicinal Chemistry Letters, Vol.50, 128324, 2021. (Summary) We have synthesized a cyan fluorescent benzothiazole-pyridinium salt composite based on D-p-A architecture. This salt was found to work as not only a two- and three-photon excitable fluorophore but also a degradation agent against amyloid fibrils under LED irradiation conditions. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.bmcl.2021.128324 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34403727 ● Search Scopus @ Elsevier (PMID): 34403727 ● Search Scopus @ Elsevier (DOI): 10.1016/j.bmcl.2021.128324 (DOI: 10.1016/j.bmcl.2021.128324, PubMed: 34403727)
15.	Keita Hoshi, Masami Itaya, Koki Tahara, Airi Matsumoto, Atsushi Tabata, Hideaki Nagamune, Yasushi Yoshida, Eiji Hase, Takeo Minamikawa, Takeshi Yasui, Tetsuro Katayama, Akihiro Furube, Keiji Minagawa, Yasushi Imada and Fumitoshi Yagishita : Two-photon excitable boron complex based on tridentate imidazo[1,5-a]pyridine ligand for heavy- atom-free mitochondria-targeted photodynamic therapy, RSC Advances, Vol.11, 26403-26407, 2021. (Tokushima University Institutional Repository) ● Metadata: 116625 (Link to Publication Site) ● Publication site (DOI): 10.1039/d1ra05059a (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1039/d1ra05059a (Tokushima University Institutional Repository: 116625, DOI: 10.1039/d1ra05059a)
16.	Eiji Hase, Yu Tokizane, Masatomo Yamagiwa, Takeo Minamikawa, Hirotsugu Yamamoto, Morohashi Isao and Takeshi Yasui : Multicascade-linked synthetic-wavelength digital holography using a line-by-line spectral-shaped optical frequency comb, Optics Express, Vol.29, No.10, 15772-15785, 2021. (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.424458 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1364/OE.424458 (DOI: 10.1364/OE.424458)
17.	Yu Tokizane, Hikaru Ejiri, Takeo Minamikawa, Safumi Suzuki, Masahiro Asada and Takeshi Yasui : Hybrid optical imaging with near-infrared, mid-infrared, and terahertz wavelengths for nondestructive inspection [Invited], Applied Optics, Vol.60, No.10, B100-B105, 2021. (Summary) Optical imaging is a powerful tool for nondestructive inspection, with high spatial resolution and low invasiveness. As lightmaterial interactions vary a great deal depending on the wavelength, it is difficult to select the best imag- ing wavelength without prior knowledge of the optical properties of the material. To overcome this difficulty, we constructed a hybrid optical imaging system using three different wavelengths: near-infrared (NIR), mid-infrared (MIR), and terahertz (THz) regions. The same imaging optics were integrated with different light sources and detectors. Depending on the lightmaterial interaction and detection sensitivity, NIR and THz imaging indicated some potential for nondestructive inspection, but MIR imaging showed difficulty. A combination of NIR and THz imaging will be a powerful tool for optical nondestructive inspection. (Link to Publication Site) ● Publication site (DOI): 10.1364/AO.415131 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33798142 ● Search Scopus @ Elsevier (PMID): 33798142 ● Search Scopus @ Elsevier (DOI): 10.1364/AO.415131 (DOI: 10.1364/AO.415131, PubMed: 33798142)
18.	Takeo Minamikawa, Takaaki Koma, Akihiro Suzuki, Takahiko Mizuno, Kentaro Nagamatsu, Hideki Arimochi, Koichiro Tsuchiya, Kaoru Matsuoka, Takeshi Yasui, Koji Yasutomo and Masako Nomaguchi : Quantitative evaluation of SARS-CoV-2 inactivation using a deep ultraviolet light-emitting diode., Scientific Reports, Vol.11, 5070, 2021. (Summary) for 300 nm are required to inactivate 99.9% of SARS-CoV-2. Our results provide quantitative antiviral effects of DUV irradiation on SARS-CoV-2, serving as basic knowledge of inactivation technologies against SARS-CoV-2. (Tokushima University Institutional Repository) ● Metadata: 117265 (Link to Publication Site) ● Publication site (DOI): 10.1038/s41598-021-84592-0 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33658595 ● Search Scopus @ Elsevier (PMID): 33658595 ● Search Scopus @ Elsevier (DOI): 10.1038/s41598-021-84592-0 (Tokushima University Institutional Repository: 117265, DOI: 10.1038/s41598-021-84592-0, PubMed: 33658595)
19.	Eiji Hase, Takeo Minamikawa, Katsuya SATO, Daisuke Yonekura, Mitsuhiko Takahashi and Takeshi Yasui : Quantitative evaluation of both histological and mechanical recovery in injured tendons using Fourier-transform second-harmonic-generation microscopy, IEEE Journal of Selected Topics in Quantum Electronics, Vol.27, No.4, 6801608, 2021. (Link to Publication Site) ● Publication site (DOI): 10.1109/JSTQE.2021.3063535 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1109/JSTQE.2021.3063535 (DOI: 10.1109/JSTQE.2021.3063535)
20.	Takahiko Mizuno, Yoshiaki Nakajima, Yuya Hata, Takuya Tsuda, Akifumi Asahara, Takashi Kato, Takeo Minamikawa, Takeshi Yasui and Kaoru Minoshima : Computationally image-corrected dual-comb microscopy with a free-running single-cavity dual-comb fiber laser, Optics Express, Vol.29, No.4, 5018-5032, 2021. (Summary) Dual-comb microscopy (DCM), an interesting imaging modality based on the optical-frequency-comb (OFC) mode and image pixel one-to-one correspondence, benefits from scan-less full-field imaging and simultaneous confocal amplitude and phase imaging. However, the two fully frequency-stabilized OFC sources requirement hampers DCM practicality due to the complexity and costs. Here, a bidirectional single-cavity dual-comb fiber laser (SCDCFL) is adopted as a DCM low-complexity OFC source. Although the residual timing jitter in the SCDCFL blurs the image of a static object acquired by DCM, computational image correction significantly suppresses the image blur. Nanometer-order step surface profilometry with a 14.0 nm uncertainty highlights the computationally image-corrected DCM effectiveness. We further discuss a possibility to expand the computational image correction to a dynamic object and demonstrate its preliminary experiment. The proposed method enhances the DCM generality and practicality due to low-complexity OFC source. (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.415242 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33726045 ● Search Scopus @ Elsevier (PMID): 33726045 ● Search Scopus @ Elsevier (DOI): 10.1364/OE.415242 (DOI: 10.1364/OE.415242, PubMed: 33726045)
21.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Yu Tokizane, Ryo Oe, Hidenori Koresawa, Hirotsugu Yamamoto and Takeshi Yasui : Full-field fluorescence lifetime dual-comb microscopy using spectral mapping and frequency multiplexing of dual-comb optical beats, Science Advances, Vol.7, No.1, eabd2102, 2021. (Summary) Fluorescence lifetime imaging microscopy (FLIM) is a powerful tool for quantitative fluorescence imaging because fluorescence lifetime is independent of concentration of fluorescent molecules or excitation/detection efficiency and is robust to photobleaching. However, since most FLIMs are based on point-to-point measurements, mechanical scanning of a focal spot is needed for forming an image, which hampers rapid imaging. Here, we demonstrate scan-less full-field FLIM based on a one-to-one correspondence between two-dimensional (2D) image pixels and frequency-multiplexed radio frequency (RF) signals. A vast number of dual-comb optical beats between dual optical frequency combs are effectively adopted for 2D spectral mapping and high-density frequency multiplexing in the RF region. Bimodal images of fluorescence amplitude and lifetime are obtained with high quantitativeness from amplitude and phase spectra of fluorescence RF comb modes without the need for mechanical scanning. The parallelized FLIM will be useful for rapid quantitative fluorescence imaging in life science. (Tokushima University Institutional Repository) ● Metadata: 116627 (Link to Publication Site) ● Publication site (DOI): 10.1126/sciadv.abd2102 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33523842 ● Search Scopus @ Elsevier (PMID): 33523842 ● Search Scopus @ Elsevier (DOI): 10.1126/sciadv.abd2102 (Tokushima University Institutional Repository: 116627, DOI: 10.1126/sciadv.abd2102, PubMed: 33523842)
22.	Takeo Minamikawa, Mayuko Shimizu, Hiroki Takanari, Yuki Morimoto, Ryosuke Shiomi, Tanioka Hiroki, Eiji Hase, Takeshi Yasui and Koichi Tsuneyama : Molecular imaging analysis of microvesicular and macrovesicular lipid droplets in non-alcoholic fatty liver disease by Raman microscopy., Scientific Reports, Vol.10, No.1, 18548, 2020. (Summary) Predominant evidence of non-alcoholic fatty liver disease (NAFLD) is the accumulation of excess lipids in the liver. A small group with NAFLD may have a more serious condition named non-alcoholic steatohepatitis (NASH). However, there is a lack of investigation of the accumulated lipids with spatial and molecular information. Raman microscopy has the potential to characterise molecular species and structures of lipids based on molecular vibration and can achieve high spatial resolution at the organelle level. In this study, we aim to demonstrate the feasibility of Raman microscopy for the investigation of NAFLD based on the molecular features of accumulated lipids. By applying the Raman microscopy to the liver of the NASH model mice, we succeeded in visualising the distribution of lipid droplets (LDs) in hepatocytes. The detailed analysis of Raman spectra revealed the difference of molecular structural features of the LDs, such as the degree of saturation of lipids in the LDs. We also found that the inhomogeneous distribution of cholesterol in the LDs depending on the histology of lipid accumulation. We visualised and characterised the lipids of NASH model mice by Raman microscopy at organelle level. Our findings demonstrated that the Raman imaging analysis was feasible to characterise the NAFLD in terms of the molecular species and structures of lipids. (Tokushima University Institutional Repository) ● Metadata: 115619 (Link to Publication Site) ● Publication site (DOI): 10.1038/s41598-020-75604-6 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33122711 ● Search Scopus @ Elsevier (PMID): 33122711 ● Search Scopus @ Elsevier (DOI): 10.1038/s41598-020-75604-6 (Tokushima University Institutional Repository: 115619, DOI: 10.1038/s41598-020-75604-6, PubMed: 33122711)
23.	Keita Hoshi, Yohei Sanagawa, Ryuta Umebayashi, Atsushi Tabata, Hideaki Nagamune, Eiji Hase, Takeo Minamikawa, Takeshi Yasui, Yasushi Yoshida, Keiji Minagawa, Yasuhiko Kawamura, Yasushi Imada and Fumitoshi Yagishita : Synthesis and Optical Property of Quadrupolar Pyridinium Salt and Its Application as Bioimaging Agent, Chemistry Letters, Vol.49, No.12, 1487-1489, 2020. (Link to Publication Site) ● Publication site (DOI): 10.1246/cl.200604 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1246/cl.200604 (DOI: 10.1246/cl.200604)
24.	Eiji Hase, Hiroki Takanari, Keita Hoshi, Masaki Okamoto, Atsushi Tabata, Hideaki Nagamune, Takeo Minamikawa, Takeshi Yasui, Yasushi Yoshida, Keiji Minagawa, Yasuhiko Kawamura, Yasushi Imada and Fumitoshi Yagishita : Two- and three-photon excitable quaternized imidazo[1,2-a]pyridines for mitochondrial imaging and potent cancer therapy agent, Organic & Biomolecular Chemistry, Vol.18, No.38, 7571-7576, 2020. (Link to Publication Site) ● Publication site (DOI): 10.1039/D0OB01585G (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32940324 ● Search Scopus @ Elsevier (PMID): 32940324 ● Search Scopus @ Elsevier (DOI): 10.1039/D0OB01585G (DOI: 10.1039/D0OB01585G, PubMed: 32940324)
25.	Hidenori Koresawa, Marc Gouryeb, Kyuki Shibuya, Takahiko Mizuno, Eiji Hase, Yu Tokizane, Ryo Oe, Takeo Minamikawa and Takeshi Yasui : Dynamic characterization of polarization property in liquid-crystal-on-silicon spatial light modulator using dual-comb spectroscopic polarimetry, Optics Express, Vol.28, No.16, 23584-23593, 2020. (Summary) Spectroscopic polarimetry (SP) is a powerful tool for characterization of thin film, polarization optics, semiconductor, and others. However, mechanical polarization modulation of broadband light hampers its application for dynamic monitoring of a sample. In this article, we demonstrate the dynamic SP with features of polarization-modulation-free polarimetry and spectrometer-free spectroscopy benefiting from dual-comb spectroscopy (DCS) using a pair of optical frequency combs (OFCs). DCS enables the direct determination of polarization without the need for polarization modulation by using mode-resolved OFC spectra of amplitude and phase for two orthogonally linear-polarized lights while securing rapid, high-precision, broadband spectroscopy without the need for spectrometer. Effectiveness of the proposed system is highlighted by visualizing the hysteresis property of dynamic response in a liquid-crystal-on-silicon spatial light modulator at a sampling rate of 105 Hz. (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.399200 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1364/OE.399200 (DOI: 10.1364/OE.399200)
26.	Jie Chen, Kazuki Nitta, Xin Zhao, Takahiko Mizuno, Takeo Minamikawa, Francis Hindle, Zheng Zheng and Takeshi Yasui : Adaptive-sampling near-Doppler-limited terahertz dual-comb spectroscopy with a free-running single-cavity fiber laser, Advanced Photonics, Vol.2, No.3, 036004, 2020. (Summary) Dual-comb spectroscopy (DCS) is an emerging spectroscopic tool with the potential to simultaneously achieve a broad spectral coverage and ultrahigh spectral resolution with rapid data acquisition. However, the need for two independently stabilized ultrafast lasers significantly hampers the potential application of DCS. We demonstrate mode-resolved DCS in the THz region based on a free-running single-cavity dual-comb fiber laser with the adaptive sampling method. While the use of a free-running single-cavity dual-comb fiber laser eliminates the need for two mode-locked lasers and their frequency control, the adaptive sampling method strongly prevents the degradation of spectroscopic performance caused by the residual timing jitter in the free-running dual-comb laser. Doppler-limit-approaching absorption features with linewidths down to 25 MHz are investigated for low-pressure acetonitrile/air mixed gas by comb-mode-resolved THz spectroscopy. The successful demonstration clearly indicates its great potential for the realization of low-complexity, Doppler-limited THz spectroscopy instrumentation. (Link to Publication Site) ● Publication site (DOI): 10.1117/1.AP.2.3.036004 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1117/1.AP.2.3.036004 (DOI: 10.1117/1.AP.2.3.036004)
27.	Takahiko Mizuno, Takuya Tsuda, Eiji Hase, Yu Tokizane, Ryo Oe, Hidenori Koresawa, Hirotsugu Yamamoto, Takeo Minamikawa and Takeshi Yasui : Optical image amplification in dual-comb microscopy, Scientific Reports, Vol.10, No.1, 8338, 2020. (Summary) Dual-comb microscopy (DCM), based on a combination of dual-comb spectroscopy (DCS) with two-dimensional spectral encoding (2D-SE), is a promising method for scan-less confocal laser microscopy giving an amplitude and phase image contrast with the confocality. However, signal loss in a 2D-SE optical system hampers increase in image acquisition rate due to decreased signal-to-noise ratio. In this article, we demonstrated optical image amplification in DCM with an erbium-doped fiber amplifier (EDFA). Combined use of the image-encoded DCS interferogram and the EDFA benefits from not only the batch amplification of amplitude and phase images but also significant rejection of amplified spontaneous emission (ASE) background. Effectiveness of the optical-image-amplified DCM is highlighted in the single-shot quantitative nanometer-order surface topography and the real-time movie of polystyrene beads dynamics under water convection. The proposed method will be a powerful tool for real-time observation of surface topography and fast dynamic phenomena. (Tokushima University Institutional Repository) ● Metadata: 115569 (Link to Publication Site) ● Publication site (DOI): 10.1038/s41598-020-64927-z (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 32433533 ● Search Scopus @ Elsevier (PMID): 32433533 ● Search Scopus @ Elsevier (DOI): 10.1038/s41598-020-64927-z (Tokushima University Institutional Repository: 115569, DOI: 10.1038/s41598-020-64927-z, PubMed: 32433533)
28.	Masatomo Yamagiwa, Takeo Minamikawa, Minamiji Fui, Takahiko Mizuno, Yu Tokizane, Oe Ryo, Koresawa Hidenori, Yasuhiro Mizutani, Tetsuo Iwata, Hirotsugu Yamamoto and Takeshi Yasui : Visualization of internal structure and internal stress in visibly opaque objects using full-field phase-shifting terahertz digital holography, Optics Express, Vol.27, No.23, 33854-33868, 2019. (Summary) We construct a full-field phase-shifting terahertz digital holography (PS-THz-DH) system by use of a THz quantum cascade laser and an uncooled, 2D micro-bolometer array. The PS-THz-DH enables us to separate the necessary diffraction-order image from unnecessary diffraction-order images without the need for spatial Fourier filtering, leading to suppress the decrease of spatial resolution. 3D shape of a visibly opaque object is visualized with a sub-millimeter lateral resolution and a sub-µm axial resolution. Also, the digital focusing of amplitude image enables the visualization of internal structure with the millimeter-order axial selectivity. Furthermore, the internal stress distribution of an externally compressed object is visualized from the phase image. The demonstrated results imply a possibility for non-destructive inspection of visibly opaque non-metal materials. (Tokushima University Institutional Repository) ● Metadata: 114124 (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.27.033854 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31878445 ● Search Scopus @ Elsevier (PMID): 31878445 ● Search Scopus @ Elsevier (DOI): 10.1364/OE.27.033854 (Tokushima University Institutional Repository: 114124, DOI: 10.1364/OE.27.033854, PubMed: 31878445)
29.	Ryo Oe, Takeo Minamikawa, Shuji Taue, Hidenori Koresawa, Takahiko Mizuno, Masatomo Yamagiwa, Yasuhiro Mizutani, Hirotsugu Yamamoto, Tetsuo Iwata and Takeshi Yasui : Refractive index sensing with temperature compensation by a multimode-interference fiber-based optical frequency comb sensing cavity, Optics Express, Vol.27, No.15, 21469-21476, 2019. (Summary) We proposed a refractive index (RI) sensing method with temperature compensation by using an optical frequency comb (OFC) sensing cavity including a multimode-interference (MMI) fiber, namely, the MMI-OFC sensing cavity. The MMI-OFC sensing cavity enables simultaneous measurement of material-dependent RI and sample temperature by decoding from the comb spacing frequency shift and the wavelength shift of the OFC. We realized the simultaneous and continuous measurement of RI-related concentration of a liquid sample and its temperature with precisions of 1.6 × 104 RIU and 0.08 °C. The proposed method would be a useful means for the various applications based on RI sensing. (Tokushima University Institutional Repository) ● Metadata: 113642 (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.27.021463 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85069881072 (Tokushima University Institutional Repository: 113642, DOI: 10.1364/OE.27.021463, Elsevier: Scopus)
30.	Hidenori Koresawa, Kyuki Shibuya, Takeo Minamikawa, Akifumi Asahara, Ryo Oe, Takahiko Mizuno, Masatomo Yamagiwa, Yasuhiro Mizutani, Tetsuo Iwata, Hirotsugu Yamamoto, Kaoru Minoshima and Takeshi Yasui : Lock-in-detection dual-comb spectroscopy, OSA Continuum, Vol.2, No.6, 1998-2007, 2019. (Summary) Dual-comb spectroscopy (DCS) is useful for gas spectroscopy due to the high potential of optical frequency comb (OFC). However, fast Fourier transform (FFT) calculation of a huge amount of temporal data spends significantly longer time than the acquisition time of an interferogram. In this article, we demonstrate frequency-domain DCS by a combination of DCS with lock-in detection, namely LID-DCS. LID-DCS directly extracts an arbitrary OFC mode from a vast number of OFC modes without the need for FFT calculation. Usefulness of LID-DCS is demonstrated in the rapid monitoring of transient signal change and spectroscopy of hydrogen cyanide gas. (Link to Publication Site) ● Publication site (DOI): 10.1364/OSAC.2.001998 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85069176229 (DOI: 10.1364/OSAC.2.001998, Elsevier: Scopus)
31.	Ryo Oe, Takeo Minamikawa, Shuji Taue, Takuya Nakahara, Hidenori Koresawa, Takahiko Mizuno, Masatomo Yamagiwa, Yasuhiro Mizutani, Hirotsugu Yamamoto, Tetsuo Iwata, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : Improvement of dynamic range and repeatability in a refractive-index- sensing optical comb by combining saturable-absorber-mirror mode- locking with an intracavity multimode interference fiber sensor, Japanese Journal of Applied Physics, Vol.58, No.6, 060912, 2019. (Summary) A mode-locked fiber comb equipped with a multimode interference fiber sensor functions as a high-precision refractive-index (RI) sensor benefitting from precise RF measurement. However, its dynamic range and repeatability are hampered by the inherent characteristics of nonlinear- polarization-rotation mode-locking oscillation. In this article, we introduce saturable-absorber-mirror mode-locking for RI sensing with a wide dynamic range and high repeatability. While the RI dynamic range was expanded to 41.4 dB due to high robustness against cavity disturbance, the self-starting capability without the need for polarization control improves the RI sensing repeatability to 1.10 × 108 for each mode-locking activation. The improved dynamic range and repeatability will be useful for enhancing the performance of RI sensing. (Tokushima University Institutional Repository) ● Metadata: 113641 (Link to Publication Site) ● Publication site (DOI): 10.7567/1347-4065/ab219a (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85069886936 (Tokushima University Institutional Repository: 113641, DOI: 10.7567/1347-4065/ab219a, Elsevier: Scopus)
32.	Takashi Ogura, Yoshiaki Nakajima, Yi-Da Hsieh, Takeo Minamikawa, Yasuhiro Mizutani, Hirotsugu Yamamoto, Tetsuo Iwata, Kaoru Minoshima and Takeshi Yasui : Lens-less fiber coupling of a 1550-nm mode-locked fiber laser light on a low-temperature-grown GaAs photoconductive antenna, OSA Continuum, Vol.2, No.4, 1310-1317, 2019. (Tokushima University Institutional Repository) ● Metadata: 113640 (Link to Publication Site) ● Publication site (DOI): 10.1364/OSAC.2.001310 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85069194963 (Tokushima University Institutional Repository: 113640, DOI: 10.1364/OSAC.2.001310, Elsevier: Scopus)
33.	Miyake Ryosuke, Nitanai Yukari, Nakagawa Yuki, Xing Junfei, Harano Koji, Nakamura Eiichi, Okabayashi Jun, Takeo Minamikawa, Uruma Keirei, Kanaizuka Katsuhiko and Kurihara Masato : Preparation of hierarchically assembled silver nanostructures based on the morphologies of crystalline peptide-silver(I) complexes, ChemPlusChem, Vol.84, No.3, 295-301, 2019. (Link to Publication Site) ● Publication site (DOI): 10.1002/cplu.201800666 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/cplu.201800666 (DOI: 10.1002/cplu.201800666)
34.	Takeo Minamikawa, Takashi Masuoka, Takashi Ogura, Kyuki Shibuya, Ryo Oe, Eiji Hase, Yoshiaki Nakajima, Yoshihisa Yamaoka, Takahiko Mizuno, Masatomo Yamagiwa, Yasuhiro Mizutani, Hirotsugu Yamamoto, Tetsuo Iwata, Kaoru Minoshima and Takeshi Yasui : Ultrasonic wave sensing using an optical-frequency-comb sensing cavity for photoacoustic imaging, OSA Continuum, Vol.2, No.2, 439-449, 2019. (Summary) We propose a novel ultrasonic wave sensing method employing an optical-frequency-comb (OFC) cavity, namely, an OFC sensing cavity-based ultrasonic wave sensor. We confirm the fundamental characteristics of the OFC sensing cavity-based ultrasonic wave sensor by using an ultrasonic wave transducer and realize the frequency response of up to 13 MHz with a linear response. We also confirm the potential applicability in photoacoustic imaging employing an 8-ns pulsed laser. Our demonstrations confirm the capability of the concept of the OFC sensing cavity in ultrasonic wave sensing and will also expand the potential of OFC technology. (Link to Publication Site) ● Publication site (DOI): 10.1364/OSAC.2.000439 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1364/OSAC.2.000439 (DOI: 10.1364/OSAC.2.000439)
35.	Katsuya SATO, Oki Matsubara, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : Quantitative in situ time-series evaluation of osteoblastic collagen synthesis under cyclic strain using second-harmonic-generation microscopy, Journal of Biomedical Optics, Vol.24, No.3, 031019, 2019. (Summary) The aim of this study is to provide an in situ method to non-invasively monitor osteoblastic collagen synthesis under mechanical stimulation. We applied second-harmonic-generation (SHG) microscopy to monitor the collagen fibers produced by osteoblast-like cells. To evaluate the influence of mechanical stimulation on collagen synthesis and maturation, we compared SHG images of osteoblast-produced collagen fibers with and without a cyclic stretch stimulus. Image analysis of the average SHG intensity indicated that the amount of osteoblastic collagen synthesis was significantly enhanced by the cyclic stretch. Furthermore, the maturity of the collagen fibers was not affected in the early stage of bone formation by the mechanical stimulus.© (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only. (Keyword) Collagen / Humans / Image Interpretation, Computer-Assisted / Microscopy / Stress, Mechanical (Link to Publication Site) ● Publication site (DOI): 10.1117/1.JBO.24.3.031019 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30635995 ● Search Scopus @ Elsevier (PMID): 30635995 ● Search Scopus @ Elsevier (DOI): 10.1117/1.JBO.24.3.031019 (DOI: 10.1117/1.JBO.24.3.031019, PubMed: 30635995)
36.	Eiji Hase, Takeo Minamikawa, Shuji Miyamoto, Ryuji Ichikawa, Yi-Da Hsieh, Yasuhiro Mizutani, Tetsuo Iwata, Hirotsugu Yamamoto and Takeshi Yasui : Scan-Less, Kilo-Pixel, Line-Field Confocal Phase Imaging with Spectrally Encoded Dual-Comb Microscopy, IEEE Journal of Selected Topics in Quantum Electronics, Vol.25, No.1, 6801408, 2018. (Summary) Confocal laser microscopy (CLM) is a powerful tool in life science research and industrial inspection, and its image acquisition rate is boosted by scan-less imaging techniques. However, the optical-intensity-based image contrast in CLM makes it difficult to visualize transparent non-fluorescent objects or reflective objects with nanometer unevenness. In this paper, we introduce an optical frequency comb (OFC) to scan-less CLM to give the optical-phase-based image contrast. One-dimensional (1D) image pixels of a sample are separately encoded onto OFC modes via 1D spectral encoding by using OFC as an optical carrier of amplitude and phase with a vast number of discrete frequency channels. Then, line-field confocal information of amplitude and phase are decoded from a mode-resolved OFC amplitude and phase spectra obtained by dual-comb spectroscopy without the need for mechanical scanning. The proposed confocal phase imaging will further expand the application fields of CLM. (Tokushima University Institutional Repository) ● Metadata: 113637 (Link to Publication Site) ● Publication site (DOI): 10.1109/JSTQE.2018.2879017 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85056348979 (Tokushima University Institutional Repository: 113637, DOI: 10.1109/JSTQE.2018.2879017, Elsevier: Scopus)
37.	Yamamoto Tsunehisa, Takeo Minamikawa, Harada Yoshinori, Yamaoka Yoshihisa, Tanaka Hideo, Yaku Hitoshi and Takamatsu Tetsuro : Label-free Evaluation of Myocardial Infarct in Surgically Excised Ventricular Myocardium by Raman Spectroscopy., Scientific Reports, Vol.8, No.1, 14671, 2018. (Summary) Understanding the viability of the ischemic myocardial tissue is a critical issue in determining the appropriate surgical procedure for patients with chronic heart failure after myocardial infarction (MI). Conventional MI evaluation methods are; however, preoperatively performed and/or give an indirect information of myocardial viability such as shape, color, and blood flow. In this study, we realize the evaluation of MI in patients undergoing cardiac surgery by Raman spectroscopy under label-free conditions, which is based on intrinsic molecular constituents related to myocardial viability. We identify key signatures of Raman spectra for the evaluation of myocardial viability by evaluating the infarct border zone myocardium that were excised from five patients under surgical ventricular restoration. We also obtain a prediction model to differentiate the infarcted myocardium from the non-infarcted myocardium by applying partial least squares regression-discriminant analysis (PLS-DA) to the Raman spectra. Our prediction model enables identification of the infarcted tissues and the non-infarcted tissues with sensitivities of 99.98% and 99.92%, respectively. Furthermore, the prediction model of the Raman images of the infarct border zone enabled us to visualize boundaries between these distinct regions. Our novel application of Raman spectroscopy to the human heart would be a useful means for the detection of myocardial viability during surgery. (Tokushima University Institutional Repository) ● Metadata: 114958 (Link to Publication Site) ● Publication site (DOI): 10.1038/s41598-018-33025-6 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30279495 ● Search Scopus @ Elsevier (PMID): 30279495 ● Search Scopus @ Elsevier (DOI): 10.1038/s41598-018-33025-6 (Tokushima University Institutional Repository: 114958, DOI: 10.1038/s41598-018-33025-6, PubMed: 30279495)
38.	Masatomo Yamagiwa, Takeo Minamikawa, Clément Trovato, Takayuki Ogawa, Dahi Abdelsalam Ghareab Ibrahim, Yusuke Kawahito, Ryo Oe, Kyuki Shibuya, Takahiko Mizuno, Emmanuel Abraham, Yasuhiro Mizutani, Tetsuo Iwata, Hirotsugu Yamamoto, Kaoru Minoshima and Takeshi Yasui : Multicascade-linked synthetic wavelength digital holography using an optical-comb-referenced frequency synthesizer, Optics Express, Vol.26, No.20, 26292-26306, 2018. (Summary) Digital holography (DH) is a promising method for non-contact surface topography because the reconstructed phase image can visualize the nanometer unevenness in a sample. However, the axial range of this method is limited to the range of the optical wavelength due to the phase wrapping ambiguity. Although the use of two different wavelengths of light and the resulting synthetic wavelength, i.e., synthetic wavelength DH, can expand the axial range up to several hundreds of millimeters, its axial precision does not reach sub-micrometer. In this article, we constructed a tunable external cavity laser diode phase-locked to an optical frequency comb, namely, an optical-comb-referenced frequency synthesizer, enabling us to generate multiple synthetic wavelengths within the range of 32 µm to 1.20 m. A multiple cascade link of the phase images among an optical wavelength ( = 1.520 µm) and 5 different synthetic wavelengths ( = 32.39 µm, 99.98 µm, 400.0 µm, 1003 µm, and 4021 µm) enables the shape measurement of a reflective millimeter-sized stepped surface with the axial resolution of 34 nm. The axial dynamic range, defined as the ratio of the axial range ( = 2.0 mm) to the axial resolution ( = 34 nm), achieves 5.9 × 10, which is larger than that of previous synthetic wavelength DH. Such a wide axial dynamic range capability will further expand the application field of DH for large objects with meter dimensions. (Tokushima University Institutional Repository) ● Metadata: 113643 (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.26.026292 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30469719 ● Summary page in Scopus @ Elsevier: 2-s2.0-85053916889 (Tokushima University Institutional Repository: 113643, DOI: 10.1364/OE.26.026292, PubMed: 30469719, Elsevier: Scopus)
39.	Yuki Ogura, Kosuke Atsuta, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : Photonic-Crystal-Fiber-Coupled, Hand-Held, Polarization-Resolved Second-Harmonic-Generation Microscope for In Vivo Visualization of Dermal Collagen Fibers in Human Skin, IEEE Journal of Selected Topics in Quantum Electronics, Vol.25, No.1, 6801007, 2018. (Summary) Second-harmonic-generation (SHG) microscopy is a powerful tool for in vivo monitoring of collagen fibers in human skin. However, its practical use in the dermatological field is still limited due to the bulky and complicated setup. In this paper, we constructed a photonic-crystal-fiber-coupled, hand-held polarization-resolved SHG microscope for in vivo monitoring of collagen fibers in human skin. Fiber delivery of ultrashort pulse light was achieved by a large-mode-area photonic-crystal-fiber whereas the SHG microscopy setup was enclosed into a hand-held probe head. The combination of PCF with the hand-held probe head largely enhances the flexibility of measurement sites in the human skin. (Tokushima University Institutional Repository) ● Metadata: 113639 (Link to Publication Site) ● Publication site (DOI): 10.1109/JSTQE.2018.2865779 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85051753929 (Tokushima University Institutional Repository: 113639, DOI: 10.1109/JSTQE.2018.2865779, Elsevier: Scopus)
40.	Guoqing Hu, Tatsuya Mizuguchi, Ryo Oe, Kazuki Nitta, Xin Zhao, Takeo Minamikawa, Ting Li, Zheng Zheng and Takeshi Yasui : Dual terahertz comb spectroscopy with a single free-running fibre laser, Scientific Reports, Vol.8, No.1, 11155, 2018. (Summary) Dual terahertz (THz) comb spectroscopy enables high spectral resolution, high spectral accuracy, and broad spectral coverage; however, the requirement for dual stabilized femtosecond lasers hampers its versatility. We here report the first demonstration of dual THz comb spectroscopy using a single free-running fibre laser. By tuning the cavity-loss-dependent gain profile with an intracavity Lyot filter together with precise management of the cavity length and dispersion, dual-wavelength comb light beams with slightly detuned repetition frequencies are generated in a single laser cavity. Due to sharing of the same cavity, such comb light beams suffer from common-mode fluctuation of the repetition frequency, and hence the corresponding frequency difference between them is passively stable around a few hundred hertz within millihertz fluctuation. While greatly reducing the size, complexity, and cost of the laser source by use of a single free-running fibre laser, the dual THz comb spectroscopy system maintains a spectral bandwidth and dynamic range of spectral power comparable to a system equipped with dual stabilized fibre lasers, and can be effectively applied to high-precision spectroscopy of acetonitrile gas at atmospheric pressure. The demonstrated results indicate that this system is an attractive solution for practical applications of THz spectroscopy and other applications. (Tokushima University Institutional Repository) ● Metadata: 112447 (Link to Publication Site) ● Publication site (DOI): 10.1038/s41598-018-29403-9 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30042440 ● Summary page in Scopus @ Elsevier: 2-s2.0-85050602942 (Tokushima University Institutional Repository: 112447, DOI: 10.1038/s41598-018-29403-9, PubMed: 30042440, Elsevier: Scopus)
41.	Ryo Oe, Shuji Taue, Takeo Minamikawa, Kohsuke Nagai, Kyuki Shibuya, Takahiko Mizuno, Masatomo Yamagiwa, Yasuhiro Mizutani, Hirotsugu Yamamoto, Tetsuo Iwata, Hideki Fukano, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : Refractive-index-sensing optical comb based on photonic radio-frequency conversion with intracavity multi-mode interference fiber sensor, Optics Express, Vol.26, No.15, 19694-19706, 2018. (Summary) Optical frequency combs (OFCs) have attracted attention as optical frequency rulers due to their tooth-like discrete spectra together with their inherent mode-locking nature and phase-locking control to a frequency standard. Based on this concept, their applications until now have been demonstrated in the fields of optical frequency metrology. However, if the utility of OFCs can be further expanded beyond their application by exploiting new aspects of OFCs, this will lead to new developments in optical metrology and instrumentation. Here, we report a fiber sensing application of OFCs based on a coherent link between the optical and radio frequencies, enabling high-precision refractive index measurement based on frequency measurement in radio-frequency (RF) region. Our technique encodes a refractive index change of a liquid sample into a repetition frequency of OFC by a combination of an intracavity multi-mode-interference fiber sensor and wavelength dispersion of a cavity fiber. Then, the change in refractive index is read out by measuring the repetition frequency in RF region based on a frequency standard. Use of an OFC as a photonic RF converter will lead to the development of new applications in high-precision fiber sensing with the help of functional fiber sensors and precise RF measurement. (Tokushima University Institutional Repository) ● Metadata: 113645 (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.26.019694 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30114139 ● Summary page in Scopus @ Elsevier: 2-s2.0-85051806746 (Tokushima University Institutional Repository: 113645, DOI: 10.1364/OE.26.019694, PubMed: 30114139, Elsevier: Scopus)
42.	Eiji Hase, Takeo Minamikawa, Takahiko Mizuno, Shuji Miyamoto, Ryuji Ichikawa, Yi-Da Hsieh, Kyuki Shibuya, Katsuya SATO, Yoshiaki Nakajima, Akifumi Asahara, Kaoru Minoshima, Yasuhiro Mizutani, Tetsuo Iwata, Hirotsugu Yamamoto and Takeshi Yasui : Scan-less confocal phase imaging based on dual-comb microscopy, Optica, Vol.5, No.5, 634-643, 2018. (Summary) Confocal laser microscopy (CLM) is a powerful tool in life science research and industrial inspection because it offers two-dimensional optical sectioning or three-dimensional imaging capability with micrometer depth selectivity. Furthermore, scan-less imaging modality enables rapid image acquisition and high robustness against surrounding external disturbances in CLM. However, the objects to be measured must be reflective, absorptive, scattering, or fluorescent because the image contrast is given by the optical intensity. If a new image contrast can be provided by the optical phase, scan-less CLM can be further applied for transparent non-fluorescent objects or reflective objects with nanometer unevenness by providing information on refractive index, optical thickness, or geometrical shape. Here, we report scan-less confocal dual-comb microscopy offering a phase image in addition to an amplitude image with depth selectivity by using an optical frequency comb as an optical carrier of amplitude and phase with discrete ultra-multichannels. Our technique encodes confocal amplitude and phase images of a sample onto a series of discrete modes in the optical frequency comb with well-defined amplitude and phase to establish a one-to-one correspondence between image pixels and comb modes. The technique then decodes these images from comb modes with amplitude and phase. We demonstrate confocal phase imaging with milliradian phase resolution under micrometer depth selectivity on the millisecond timescale. As a proof of concept, we demonstrate the quantitative phase imaging of standing culture fixed cells and the surface topography of nanometer-scale step structures. Our technique for confocal phase imaging will find applications in three-dimensional visualization of stacked living cells in culture and nanometer surface topography of semiconductor objects. (Tokushima University Institutional Repository) ● Metadata: 113646 (Link to Publication Site) ● Publication site (DOI): 10.1364/OPTICA.5.000634 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85047275172 (Tokushima University Institutional Repository: 113646, DOI: 10.1364/OPTICA.5.000634, Elsevier: Scopus)
43.	Eiji Hase, Takeo Minamikawa, Shuji Miyamoto, Yasuhiro Mizutani, Tetsuo Iwata, Hirotsugu Yamamoto and Takeshi Yasui : Application of Scan-less Two-Dimensional Confocal Microscopy Based on a Combination of Confocal Slit With Wavelength/Space Conversion, IEEE Journal of Selected Topics in Quantum Electronics, Vol.25, No.1, 7101407, 2018. (Summary) Confocal laser microscope (CLM) has been widely used in the fields of the non-contact surface topography, biomedical imaging, and other applications, because the confocality gives two-dimensional (2D) optical-sectioning or three-dimensional (3D) imaging capability with the depth selectivity. Combination of line-focused CLM with one-dimensional (1D) spectral encoding CLM enables us to obtain the 2D confocal image without the need for the mechanical scanning. So-called scan-less 2D CLM is a unique imaging modality, however, there are no attempts to apply for practical application. In this paper, we constructed scan-less 2D CLM with the image acquisition time of 0.23 ms, the lateral resolution of 1.2 μm, the depth resolution of 2.4 μm, and apply it for different kinds of application to evaluate its practical potential. (Tokushima University Institutional Repository) ● Metadata: 113638 (Link to Publication Site) ● Publication site (DOI): 10.1109/JSTQE.2018.2869615 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85053132099 (Tokushima University Institutional Repository: 113638, DOI: 10.1109/JSTQE.2018.2869615, Elsevier: Scopus)
44.	Takeo Minamikawa, Takashi Ogura, Yoshiaki Nakajima, Eiji Hase, Yasuhiro Mizutani, Hirotsugu Yamamoto, Kaoru Minoshima and Takeshi Yasui : Strain sensing based on strain to radio-frequency conversion of optical frequency comb, Optics Express, Vol.26, No.8, 9484-9491, 2018. (Summary) We propose an optical frequency comb (OFC)-based strain sensing method, namely OFC sensing cavity, which is capable of radio-frequency (RF)-based strain measurement. We developed a null-method-based strain sensing system with a comb-spacing-stabilized OFC generator. We realized strain measurement from 1.83 µ to 1800 µ with a sensing fiber length of 20 mm. The measurable strain frequency range of the developed strain sensing system was from 0 to 310 Hz. Owing to the use of RF-based strain measurement, our approach would be a useful and powerful tool for sensing of strain or other physical quantities, and the concept of the OFC sensing cavity is a new aspect of OFC technology. (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.26.009484 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29715898 ● Summary page in Scopus @ Elsevier: 2-s2.0-85045550276 (DOI: 10.1364/OE.26.009484, PubMed: 29715898, Elsevier: Scopus)
45.	Masatomo Yamagiwa, Takayuki Ogawa, Takeo Minamikawa, Dahi Ghareab Abdelsalam, Kyosuke Okabe, Noriaki Tsurumachi, Yasuhiro Mizutani, Tetsuo Iwata, Hirotsugu Yamamoto and Takeshi Yasui : Real-Time Amplitude and Phase Imaging of Optically Opaque Objects by Combining Full-Field Off-Axis Terahertz Digital Holography with Angular Spectrum Reconstruction, Journal of Infrared, Millimeter and Terahertz Waves, Vol.39, No.6, 561-572, 2018. (Summary) Terahertz digital holography (THz-DH) has the potential to be used for non-destructive inspection of visibly opaque soft materials due to its good immunity to optical scattering and absorption. Although previous research on full-field off-axis THz-DH has usually been performed using Fresnel diffraction reconstruction, its minimum reconstruction distance occasionally prevents a sample from being placed near a THz imager to increase the signal-to-noise ratio in the hologram. In this article, we apply the angular spectrum method (ASM) for wavefront reconstruction in full-filed off-axis THz-DH because ASM is more accurate at short reconstruction distances. We demonstrate real-time phase imaging of a visibly opaque plastic sample with a phase resolution power of λ/49 at a frame rate of 3.5 Hz in addition to real-time amplitude imaging. We also perform digital focusing of the amplitude image for the same object with a depth selectivity of 447 μm. Furthermore, 3D imaging of visibly opaque silicon objects was achieved with a depth precision of 1.7 μm. The demonstrated results indicate the high potential of the proposed method for in-line or in-process non-destructive inspection of soft materials. (Link to Publication Site) ● Publication site (DOI): 10.1007/s10762-018-0482-6 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85044753790 (DOI: 10.1007/s10762-018-0482-6, Elsevier: Scopus)
46.	Takeo Minamikawa, Yoshinori Murakami, Naokazu Matsumura, Hirohiko Niioka, Shuichiro Fukushima, Tsutomu Araki and Mamoru Hashimoto : Photo-induced cell damage analysis for single- and multi-focus coherent anti-Stokes Raman scattering microscopy, Journal of Spectroscopy, Vol.2017, 5725340, 2017. (Tokushima University Institutional Repository) ● Metadata: 115568 (Link to Publication Site) ● Publication site (DOI): 10.1155/2017/5725340 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1155/2017/5725340 (Tokushima University Institutional Repository: 115568, DOI: 10.1155/2017/5725340)
47.	Takeo Minamikawa, Nagai Daiki, Kaneko Takaaki, Taniguchi Ittetsu, Ando Mariko, Akama Ryo and Takenaka Kenji : Analytical imaging of colour pigments used in Japanese woodblock prints using Raman microspectroscopy, Journal of Raman Spectroscopy, Vol.48, No.12, 1887-1895, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1002/jrs.5263 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1002/jrs.5263 (DOI: 10.1002/jrs.5263)
48.	Takeo Minamikawa, Yi-Da Hsieh, Kyuki Shibuya, Eiji Hase, Yoshiki Kaneoka, Sho Okubo, Hajime Inaba, Yasuhiro Mizutani, Hirotsugu Yamamoto, Tetsuo Iwata and Takeshi Yasui : Dual-comb spectroscopic ellipsometry., Nature Communications, Vol.8, 610, 2017. (Summary) Spectroscopic ellipsometry is a means of investigating optical and dielectric material responses. Conventional spectroscopic ellipsometry is subject to trade-offs between spectral accuracy, resolution, and measurement time. Polarization modulation has afforded poor performance because of its sensitivity to mechanical vibrational noise, thermal instability, and polarization-wavelength dependency. We combine spectroscopic ellipsometry with dual-comb spectroscopy, namely, dual-comb spectroscopic ellipsometry. Dual-comb spectroscopic ellipsometry (DCSE). DCSE directly and simultaneously obtains the ellipsometric parameters of the amplitude ratio and phase difference between s-polarized and p-polarized light signals with ultra-high spectral resolution and no polarization modulation, beyond the conventional limit. Ellipsometric evaluation without polarization modulation also enhances the stability and robustness of the system. In this study, we construct a polarization-modulation-free DCSE system with a spectral resolution of up to 1.2 × 10(-5) nm throughout the spectral range of 1514-1595 nm and achieved an accuracy of 38.4 nm and a precision of 3.3 nm in the measurement of thin-film samples.Spectroscopic ellipsometry is an established technique to characterize the optical properties of a material. Here, Minamikawa et al. combine the method with dual-comb spectroscopy, which allows them to obtain ellipsometric parameters including the phase difference between s-polarized and p-polarized light. (Tokushima University Institutional Repository) ● Metadata: 112462 (Link to Publication Site) ● Publication site (DOI): 10.1038/s41467-017-00709-y (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28931818 ● Search Scopus @ Elsevier (PMID): 28931818 ● Search Scopus @ Elsevier (DOI): 10.1038/s41467-017-00709-y (Tokushima University Institutional Repository: 112462, DOI: 10.1038/s41467-017-00709-y, PubMed: 28931818)
49.	Kyuki Shibuya, Takeo Minamikawa, Yasuhiro Mizutani, Hirotsugu Yamamoto, Kaoru Minoshima, Takeshi Yasui and Tetsuo Iwata : Scan-less hyperspectral dual-comb single-pixel-imaging in both amplitude and phase., Optics Express, Vol.25, No.18, 21947-21957, 2017. (Summary) We have developed a hyperspectral imaging scheme that involves a combination of dual-comb spectroscopy and Hadamard-transform-based single-pixel imaging. The scheme enables us to obtain 12,000 hyperspectral images of amplitude and phase at a spatial resolution of 46 µm without mechanical scanning. The spectral resolution given by the data point interval in the frequency domain is 20 MHz and the comb mode interval is 100 MHz over a spectral range of 1.2 THz centered at 191.5 THz. As an initial demonstration of our scheme, we obtained spectroscopic images of a standard test chart through an etalon plate. The thickness of an absorptive chromium-coated layer on a float-glass substrate was determined to be 70 nm from the hyperspectral phase images in the near-infrared wavelength region. (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.25.021947 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 29041485 ● Summary page in Scopus @ Elsevier: 2-s2.0-85029211610 (DOI: 10.1364/OE.25.021947, PubMed: 29041485, Elsevier: Scopus)
50.	Hisataka Matsuo, Yoshinori Harada, Takeo Minamikawa, Yoshiyuki Kato, Yasutoshi Murayama, Eigo Otsuji, Tetsuro Takamatsu and Hideo Tanaka : Efficient fluorescence detection of protoporphyrin IX in metastatic lymph nodes of murine colorectal cancer stained with indigo carmine., Photodiagnosis and Photodynamic Therapy, Vol.19, 175-180, 2017. (Summary) Protoporphyrin IX (PpIX), a biochemical converted from 5-aminolevulinc acid (5-ALA) in living cells, is useful for intraoperative fluorescent detection of cancer metastasis in lymph nodes (LNs). However, unknown is whether the fluorescence of PpIX can be detected in the LNs when they coexist with indigo carmine, a blue dye commonly used for identification of sentinel LNs during surgery. To address this issue, we sought to evaluate the diagnostic usefulness of PpIX fluorescence in the presence of indigo carmine in a mouse LN metastasis model of rectal cancer after administration of 5-ALA. Spectral analysis of pure chemicals revealed that the absorption spectrum of indigo carmine widely overlapped with the fluorescence spectrum of PpIX specifically at the peak of 632nm, a common emission wavelength for detecting PpIX, but not at the other peak of 700nm. Due to such spectral overlap, the PpIX fluorescence intensity was significantly attenuated by mixture with indigo carmine at 632nm, but not at 700nm. Accordingly, fluorescent measurements of the mouse metastatic LN revealed more intense presentation of PpIX at 700nm than at 632nm, indicating that the diagnostic usefulness is greater at 700nm than at 632nm for the indigo carmine-dyed LNs after administration of 5-ALA. From these observations, we propose that the fluorescence measurement is more efficient at 700nm than at 632nm for detection of PpIX in metastatic LNs stained with indigo carmine. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.pdpdt.2017.05.019 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28578125 ● Search Scopus @ Elsevier (PMID): 28578125 ● Search Scopus @ Elsevier (DOI): 10.1016/j.pdpdt.2017.05.019 (DOI: 10.1016/j.pdpdt.2017.05.019, PubMed: 28578125)
51.	Yuki Ogura, Kohsuke Atsuta, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : Hand-held Second-harmonic-generation (SHG) Microscope for Dermatological Application, Transactions of the Japanese Society for Medical and Biological Engineering, Vol.55, No.2, 91-96, 2017. (Summary) Second harmonic generation (SHG) microscopy allows <i>in situ</i> visualization of dermal collagen fibers in human skin due to its selectivity for collagen fiber. It is an attractive tool because it does not require staining, is non-invasiveness, and has high-resolution 3D imaging capability. However, its practical use in the dermatological field is still limited due to the bulky and complicated setup. Incorporation of fiber transmission of the laser light and a compact probe head into the microscope would enhance its compactness, robustness, flexibility, and hence convenience. In this study, we constructed a photonic-crystal-fiber (PCF) -coupled, hand-held SHG microscope for <i>in situ</i> monitoring of collagen fibers in human skin. By transmitting pulse light from a mode-locked Cr:Forsterite laser source via a large mode area PCF, it was possible to deliver pulse light with median wavelength of 1250nm and pulse width of 80 fs to the SHG microscope, without the need for external dispersion compensation. Components of a SHG microscope;galvano mirrors, relay lenses, objective lens, dichroic mirror, optical filters, and photon-counting photomultiplier, were mounted into a hand-held probe head (width=310mm, height=150mm, and depth=50mm), which is only 2% of the size of a conventional SHG microscope. We compared the imaging performance between the conventional SHG microscope and the hand-held SHG microscope, and confirmed comparable performance of the two. Finally, we demonstrated <i>in situ</i> visualization of collagen fibers in human skin using the hand-held SHG microscope with a compact probe head coupled to PCF. The hand-held SHG microscope greatly enhances the operability of <i>in situ</i> measurement of the human skin. The novel system will be a powerful tool for various dermatological applications. (Link to Publication Site) ● Publication site (DOI): 10.11239/jsmbe.55.91 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282680245915008 ● Search Scopus @ Elsevier (DOI): 10.11239/jsmbe.55.91 (DOI: 10.11239/jsmbe.55.91, CiNii: 1390282680245915008)
52.	Guoqing Hu, Tatsuya Mizuguchi, Xin Zhao, Takeo Minamikawa, Takahiko Mizuno, Yuli Yang, Cui Li, Ming Bai, Zheng Zheng and Takeshi Yasui : Measurement of absolute frequency of continuous-wave terahertz radiation in real time using a free-running, dual-wavelength mode-locked, erbium-doped fibre laser., Scientific Reports, Vol.7, 42082, 2017. (Summary) A single, free-running, dual-wavelength mode-locked, erbium-doped fibre laser was exploited to measure the absolute frequency of continuous-wave terahertz (CW-THz) radiation in real time using dual THz combs of photo-carriers (dual PC-THz combs). Two independent mode-locked laser beams with different wavelengths and different repetition frequencies were generated from this laser and were used to generate dual PC-THz combs having different frequency spacings in photoconductive antennae. Based on the dual PC-THz combs, the absolute frequency of CW-THz radiation was determined with a relative precision of 1.2 × 10(-9) and a relative accuracy of 1.4 × 10(-9) at a sampling rate of 100 Hz. Real-time determination of the absolute frequency of CW-THz radiation varying over a few tens of GHz was also demonstrated. Use of a single dual-wavelength mode-locked fibre laser, in place of dual mode-locked lasers, greatly reduced the size, complexity, and cost of the measurement system while maintaining the real-time capability and high measurement precision. (Tokushima University Institutional Repository) ● Metadata: 112339 (Link to Publication Site) ● Publication site (DOI): 10.1038/srep42082 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28186148 ● Search Scopus @ Elsevier (PMID): 28186148 ● Search Scopus @ Elsevier (DOI): 10.1038/srep42082 (Tokushima University Institutional Repository: 112339, DOI: 10.1038/srep42082, PubMed: 28186148)
53.	Suguru Ohira, Hideo Tanaka, Yoshinori Harada, Takeo Minamikawa, Yasuaki Kumamoto, Satoaki Matoba, Hitoshi Yaku and Tetsuro Takamatsu : Label-free detection of myocardial ischaemia in the perfused rat heart by spontaneous Raman spectroscopy., Scientific Reports, Vol.7, 42401, 2017. (Summary) Raman spectroscopy, which identifies intrinsic molecular constituents, has a potential for determining myocardial viability under label-free conditions. However, its suitability for evaluating myocardial ischaemia is undetermined. Focusing on cytochromes, i.e., representative molecules reflecting mitochondrial activity, we tested whether Raman spectroscopy is applicable for evaluating myocardial ischaemia especially during early ischaemic phase. We obtained spontaneous Raman spectra of the subepicardial myocardium in the Langendorff-perfused rat heart upon 532-nm excitation before and during the "stopped-flow," global ischaemia. Semi-quantitative values of the peak intensities at 750 and 1127 cm(-1), which reflect reduced cytochromes c and b, increased immediately and progressively after induction of the stopped flow, indicating progressive reduction of the mitochondrial respiration. Such spectral changes emerged before the loss of 1) mitochondrial membrane potentials measured by the fluorescence intensity of tetramethyl rhodamine ethyl ester or 2) staining of the triphenyl tetrazolium chloride dye in the myocardium. The progressive increases in the Raman peaks by stopped flow were significantly retarded by ischaemic preconditioning. Sequential measurements of the peak intensities at 750 and 1127 cm(-1) enabled early detection of the myocardial ischaemia based on the mitochondrial functions. These data suggest that Raman spectroscopy offers the potential to evaluate acute ischaemic heart under label-free conditions. (Tokushima University Institutional Repository) ● Metadata: 112336 (Link to Publication Site) ● Publication site (DOI): 10.1038/srep42401 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 28186163 ● Summary page in Scopus @ Elsevier: 2-s2.0-85012066343 (Tokushima University Institutional Repository: 112336, DOI: 10.1038/srep42401, PubMed: 28186163, Elsevier: Scopus)
54.	Eiji Hase, Takeo Minamikawa, Katsuya SATO, Daisuke Yonekura, Mitsuhiko Takahashi and Takeshi Yasui : Observation of Tendon Healing with Second-harmonic-generation (SHG) Microscopy, Transactions of the Japanese Society for Medical and Biological Engineering, Vol.54, No.6, 253-260, 2016. (Summary) <p>Tendon rupture is a traumatic injury that is difficult to recover to the condition before injury. In previous studies, histological staining and tensile testing have been widely used to evaluate histological and mechanical healing. However, since both methods are destructive and invasive, it is difficult to apply these methods to clinical diagnosis. If the degree of healing can be visualized nondestructively and noninvasively, new findings may be obtained regarding mechanisms of the tendon healing process. In this study, we used second-harmonic-generation (SHG) microscopy to evaluate the degree of healing of ruptured tendon in a rabbit model. SHG microscopy has high selectivity and high image contrast with respect to the structural maturity, density, and aggregates of collagen molecule, without the need for histological sectioning and staining. Furthermore, since SHG light intensity sensitively reflects the structural maturity of collagen molecule and its aggregates, it has the potential to be a good indicator for the degree of healing of the injured tendon. By comparing the SHG images between 4-week-healing tendons and normal tendons in the animal model, we confirmed that SHG light intensity of the healing tendon was significantly lower than that of the normal tendon, indicating that the collagen structure in the healing tendon is still immature. Furthermore, we performed image analysis based on 2D Fourier transform of the acquired SHG images, and confirmed a significant difference in collagen distribution depending on the sample. These results indicate that SHG microscopy has the unique potential as an indicator of tendon healing.</p> (Keyword) second-harmonic-generation / microscopy / tendon / collagen / healing / image analysis (Link to Publication Site) ● Publication site (DOI): 10.11239/jsmbe.54.253 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390001205270574720 ● Search Scopus @ Elsevier (DOI): 10.11239/jsmbe.54.253 (DOI: 10.11239/jsmbe.54.253, CiNii: 1390001205270574720)
55.	Eiji Hase, Katsuya SATO, Daisuke Yonekura, Takeo Minamikawa, Mitsuhiko Takahashi and Takeshi Yasui : Evaluation of the histological and mechanical features of tendon healing in a rabbit model with the use of second-harmonic-generation imaging and tensile testing, Bone & Joint Research, Vol.5, No.11, 577-585, 2016. (Summary) This study aimed to evaluate the histological and mechanical features of tendon healing in a rabbit model with second-harmonic-generation (SHG) imaging and tensile testing. A total of eight male Japanese white rabbits were used for this study. The flexor digitorum tendons in their right leg were sharply transected, and then were repaired by intratendinous stitching. At four weeks post-operatively, the rabbits were killed and the flexor digitorum tendons in both right and left legs were excised and used as specimens for tendon healing (n = 8) and control (n = 8), respectively. Each specimen was examined by SHG imaging, followed by tensile testing, and the results of the two testing modalities were assessed for correlation. While the SHG light intensity of the healing tendon samples was significantly lower than that of the uninjured tendon samples, 2D Fourier transform SHG images showed a clear difference in collagen fibre structure between the uninjured and the healing samples, and among the healing samples. The mean intensity of the SHG image showed a moderate correlation (R(2) = 0.37) with Young's modulus obtained from the tensile testing. Our results indicate that SHG microscopy may be a potential indicator of tendon healing.Cite this article: E. Hase, K. Sato, D. Yonekura, T. Minamikawa, M. Takahashi, T. Yasui. Evaluation of the histological and mechanical features of tendon healing in a rabbit model with the use of second-harmonic-generation imaging and tensile testing. Bone Joint Res 2016;5:577-585. DOI: 10.1302/2046-3758.511.BJR-2016-0162.R1. (Tokushima University Institutional Repository) ● Metadata: 115027 (Link to Publication Site) ● Publication site (DOI): 10.1302/2046-3758.511.BJR-2016-0162.R1 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27881441 ● Search Scopus @ Elsevier (PMID): 27881441 ● Search Scopus @ Elsevier (DOI): 10.1302/2046-3758.511.BJR-2016-0162.R1 (Tokushima University Institutional Repository: 115027, DOI: 10.1302/2046-3758.511.BJR-2016-0162.R1, PubMed: 27881441)
56.	Shuji Miyamoto, Eiji Hase, Takeo Minamikawa, Yi-Da Hsieh, Yasuhiro Mizurani, Tetsuo Iwata, Takeshi Yasui and Hirotsugu Yamamoto : Scan-Less Full-Field Confocal Microscopy by a Combination of Confocal Slit with Wavelength/Space Conversion, Journal of the Japan Society for Precision Engineering, Vol.82, No.7, 679-682, 2016. (Link to Publication Site) ● Publication site (DOI): 10.2493/jjspe.82.679 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.2493/jjspe.82.679 (DOI: 10.2493/jjspe.82.679)
57.	Yi-Da Hsieh, Shota Nakamura, Ghareab Dahi Abdelsalam, Takeo Minamikawa, Yasuhiro Mizutani, Hirotsugu Yamamoto, Tetsuo Iwata, Francis Hindle and Takeshi Yasui : Dynamic terahertz spectroscopy of gas molecules mixed with unwanted aerosol under atmospheric pressure using fibre-based asynchronous-optical-sampling terahertz time-domain spectroscopy., Scientific Reports, Vol.6, 28114, 2016. (Summary) Terahertz (THz) spectroscopy is a promising method for analysing polar gas molecules mixed with unwanted aerosols due to its ability to obtain spectral fingerprints of rotational transition and immunity to aerosol scattering. In this article, dynamic THz spectroscopy of acetonitrile (CH3CN) gas was performed in the presence of smoke under the atmospheric pressure using a fibre-based, asynchronous-optical-sampling THz time-domain spectrometer. To match THz spectral signatures of gas molecules at atmospheric pressure, the spectral resolution was optimized to 1 GHz with a measurement rate of 1 Hz. The spectral overlapping of closely packed absorption lines significantly boosted the detection limit to 200 ppm when considering all the spectral contributions of the numerous absorption lines from 0.2 THz to 1 THz. Temporal changes of the CH3CN gas concentration were monitored under the smoky condition at the atmospheric pressure during volatilization of CH3CN droplets and the following diffusion of the volatilized CH3CN gas without the influence of scattering or absorption by the smoke. This system will be a powerful tool for real-time monitoring of target gases in practical applications of gas analysis in the atmospheric pressure, such as combustion processes or fire accident. (Tokushima University Institutional Repository) ● Metadata: 112320 (Link to Publication Site) ● Publication site (DOI): 10.1038/srep28114 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27301319 ● Summary page in Scopus @ Elsevier: 2-s2.0-84974831427 (Tokushima University Institutional Repository: 112320, DOI: 10.1038/srep28114, PubMed: 27301319, Elsevier: Scopus)
58.	Takeo Minamikawa, Hisataka Matsuo, Yoshiyuki Kato, Yoshinori Harada, Eigo Otsuji, Akio Yanagisawa, Hideo Tanaka and Tetsuro Takamatsu : Simplified and optimized multispectral imaging for 5-ALA-based fluorescence diagnosis of malignant lesions., Scientific Reports, Vol.6, 25530, 2016. (Summary) 5-aminolevulinic acid (5-ALA)-based fluorescence diagnosis is now clinically applied for accurate and ultrarapid diagnosis of malignant lesions such as lymph node metastasis during surgery. 5-ALA-based diagnosis evaluates fluorescence intensity of a fluorescent metabolite of 5-ALA, protoporphyrin IX (PPIX); however, the fluorescence of PPIX is often affected by autofluorescence of tissue chromophores, such as collagen and flavins. In this study, we demonstrated PPIX fluorescence estimation with autofluorescence elimination for 5-ALA-based fluorescence diagnosis of malignant lesions by simplified and optimized multispectral imaging. We computationally optimized observation wavelength regions for the estimation of PPIX fluorescence in terms of minimizing prediction error of PPIX fluorescence intensity in the presence of typical chromophores, collagen and flavins. By using the fluorescence intensities of the optimized wavelength regions, we verified quantitative detection of PPIX fluorescence by using chemical mixtures of PPIX, flavins, and collagen. Furthermore, we demonstrated detection capability by using metastatic and non-metastatic lymph nodes of colorectal cancer patients. These results suggest the potential and usefulness of the background-free estimation method of PPIX fluorescence for 5-ALA-based fluorescence diagnosis of malignant lesions, and we expect this method to be beneficial for intraoperative and rapid cancer diagnosis. (Tokushima University Institutional Repository) ● Metadata: 112316 (Link to Publication Site) ● Publication site (DOI): 10.1038/srep25530 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27149301 ● Summary page in Scopus @ Elsevier: 2-s2.0-84966700309 (Tokushima University Institutional Repository: 112316, DOI: 10.1038/srep25530, PubMed: 27149301, Elsevier: Scopus)
59.	Eiji Hase, Oki Matsubara, Takeo Minamikawa, Katsuya SATO and Takeshi Yasui : In situ time-series monitoring of collagen fibers produced by standing-cultured osteoblasts using a second-harmonic-generation microscope., Applied Optics, Vol.55, No.12, 3261-3267, 2016. (Summary) In bone tissue engineering and regeneration, there is a considerable need for an unstained method of monitoring collagen fibers produced by osteoblasts. This is because collagen fibers play an important role as a bone matrix and continuous monitoring of their temporal dynamics is important in clarifying the organization process toward forming bone tissue. In the work described here, using a second-harmonic-generation (SHG) microscope, we performed in situ time-series monitoring of collagen fibers produced by cultured osteoblasts without the need for staining. Use of the 19 fs near-infrared pulsed light enables us to visualize the temporal dynamics in a thin layer of collagen fibers produced by a single layer of osteoblasts in high-contrast SHG images. While the collagen fibers were produced and stored inside the osteoblasts at an early stage of culturing, the network structure of collagen fibers was formed and locally condensed at a late stage. Furthermore, we extracted a quantitative parameter of collagen maturity degree in the cultured sample by use of image analysis based on a two-dimensional Fourier transform of the SHG image. The proposed method will be useful for in situ quality and quantity control of collagen fibers in bone tissue engineering and regeneration. (Link to Publication Site) ● Publication site (DOI): 10.1364/AO.55.003261 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27140096 ● Summary page in Scopus @ Elsevier: 2-s2.0-84964507940 (DOI: 10.1364/AO.55.003261, PubMed: 27140096, Elsevier: Scopus)
60.	Yi-Da Hsieh, Hiroto Kimura, Kenta Hayashi, Takeo Minamikawa, Yasuhiro Mizutani, Hirotsugu Yamamoto, Tetsuo Iwata, Hajime Inaba, Kaoru Minoshima, Francis Hindle and Takeshi Yasui : Terahertz frequency-domain spectroscopy of low-pressure acetonitrile gas by a Photomixing terahertz synthesizer referenced to dual optical frequency combs, Journal of Infrared, Millimeter and Terahertz Waves, Vol.37, No.9, 903-915, 2016. (Link to Publication Site) ● Publication site (DOI): 10.1007/s10762-016-0277-6 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84965029481 (DOI: 10.1007/s10762-016-0277-6, Elsevier: Scopus)
61.	Koizumi Noriaki, Harada Yoshinori, Beika Masatomo, Takeo Minamikawa, Yamaoka Yoshihisa, Dai Ping, Murayama Yasutoshi, Yanagisawa Akio, Otsuji Eigo, Tanaka Hideo and Takamatsu Tetsuro : Highly sensitive fluorescence detection of metastatic lymph nodes of gastric cancer with photo-oxidation of protoporphyrin IX., EJSO - European Journal of Surgical Oncology, Vol.42, No.8, 1236-1246, 2016. (Summary) We established a highly sensitive and specific 5-ALA-induced fluorescence imaging method applicable in clinical settings. The novel method has a potential to become a useful tool for intraoperative rapid diagnosis of LN metastasis. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.ejso.2016.03.003 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27055944 ● Search Scopus @ Elsevier (PMID): 27055944 ● Search Scopus @ Elsevier (DOI): 10.1016/j.ejso.2016.03.003 (DOI: 10.1016/j.ejso.2016.03.003, PubMed: 27055944)
62.	Takeo Minamikawa, Daiki NAGAI, Takaaki KANEKO, Ittetsu TANIGUCHI, Yoshinori Harada, Tetsuro Takamatsu and Kenji TAKENAKA : Development of molecular distribution analysis method of color pigments on Japanese woodblock prints by Raman spectral-imagin, Journal of Japan Society of Information and Knowledge, Vol.26, No.1, 1-10, 2016. (Summary) Ukiyo-e prints, Japanese multicolor woodblock prints, is a traditional Japanese art that has been flourished since Edo period. To surmise the production technologies of woodblock prints, such as materials, carving technologies, and printing technologies, detailed analysis of color pigments that are one of the most important essential materials used in woodblock prints is required. In this study, we proposed a noninvasive analytical method of color pigments by means of Raman spectral-imaging. Pigment species and its molecular structures were clarified via Raman spectra of pigments. Raman imaging of woodblock prints revealed pigment distribution in plane and cross-section, which provided adhesion states of pigments on paper fibers. We also visualized a different pigment distribution on paper depending on glue content in pigment mixture. Our results indicated that Raman spectral-imaging would be a promising technique for evaluating a production technologies of ancient ukiyo-e prints that was still unknown at present. (Tokushima University Institutional Repository) ● Metadata: 111996 (Link to Publication Site) ● Publication site (DOI): 10.2964/jsik_2015_021 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390282679401535616 ● Search Scopus @ Elsevier (DOI): 10.2964/jsik_2015_021 (Tokushima University Institutional Repository: 111996, DOI: 10.2964/jsik_2015_021, CiNii: 1390282679401535616)
63.	Takeo Minamikawa, Kenta Hayashi, Tatsuya Mizuguchi, Yi-Da Hsieh, Dahi Ghareab Abdelsalam, Yasuhiro Mizurani, Hirotsugu Yamamoto, Tetsuo Iwata and Takeshi Yasui : Real-time determination of absolute frequency in continuous-wave terahertz radiation with a photocarrier terahertz frequency comb induced by an unstabilized femtosecond laser, Journal of Infrared, Millimeter and Terahertz Waves, Vol.37, No.5, 473-485, 2016. (Link to Publication Site) ● Publication site (DOI): 10.1007/s10762-015-0237-6 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84953218857 (DOI: 10.1007/s10762-015-0237-6, Elsevier: Scopus)
64.	Takeo Minamikawa, Yoshinori Harada and Tetsuro Takamatsu : Ex vivo peripheral nerve detection of rats by spontaneous Raman spectroscopy., Scientific Reports, Vol.5, No.25, 2015. (Summary) Nerve-sparing surgery is increasingly being applied to avoid functional deficits of the limbs and organs following surgery. Peripheral nerves that should be preserved are, however, sometimes misidentified due to similarity of shape and color to non-nerve tissues. To avoid misidentification of peripheral nerves, development of an in situ nerve detection method is desired. In this study, we report the label-free detection of ex vivo peripheral nerves of Wistar rats by using Raman spectroscopy. We obtained Raman spectra of peripheral nerves (myelinated and unmyelinated nerves) and their adjacent tissues of Wistar rats without any treatment such as fixation and/or staining. For the identification of tissue species and further analysis of spectral features, we proposed a principal component regression-based discriminant analysis with representative Raman spectra of peripheral nerves and their adjacent tissues. Our prediction model selectively detected myelinated nerves and unmyelinated nerves of Wistar rats with respective sensitivities of 95.5% and 88.3% and specificities of 99.4% and 93.5%. Furthermore, important spectral features for the identification of tissue species were revealed by detailed analysis of principal components of representative Raman spectra of tissues. Our proposed approach may provide a unique and powerful tool for peripheral nerve detection for nerve-sparing surgery in the future. (Link to Publication Site) ● Publication site (DOI): 10.1038/srep17165 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26602842 ● Summary page in Scopus @ Elsevier: 2-s2.0-84948186305 (DOI: 10.1038/srep17165, PubMed: 26602842, Elsevier: Scopus)
65.	Yoshiyuki Arai, Takayuki Yamamoto, Takeo Minamikawa, Tetsuro Takamatsu and Takeharu Nagai : Spectral fingerprinting of individual cells visualized by cavity-reflection-enhanced light-absorption microscopy., PLoS ONE, Vol.10, No.5, 2015. (Summary) The absorption spectrum of light is known to be a "molecular fingerprint" that enables analysis of the molecular type and its amount. It would be useful to measure the absorption spectrum in single cell in order to investigate the cellular status. However, cells are too thin for their absorption spectrum to be measured. In this study, we developed an optical-cavity-enhanced absorption spectroscopic microscopy method for two-dimensional absorption imaging. The light absorption is enhanced by an optical cavity system, which allows the detection of the absorption spectrum with samples having an optical path length as small as 10 m, at a subcellular spatial resolution. Principal component analysis of various types of cultured mammalian cells indicates absorption-based cellular diversity. Interestingly, this diversity is observed among not only different species but also identical cell types. Furthermore, this microscopy technique allows us to observe frozen sections of tissue samples without any staining and is capable of label-free biopsy. Thus, our microscopy method opens the door for imaging the absorption spectra of biological samples and thereby detecting the individuality of cells. (Keyword) Animals / COS Cells / Cercopithecus aethiops / HeLa Cells / Humans / Light / Mice / Microscopy / NIH 3T3 Cells / PC12 Cells / Principal Component Analysis / Rats / Single-Cell Analysis (Link to Publication Site) ● Publication site (DOI): 10.1371/journal.pone.0125733 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25950513 ● Summary page in Scopus @ Elsevier: 2-s2.0-84929104073 (DOI: 10.1371/journal.pone.0125733, PubMed: 25950513, Elsevier: Scopus)
66.	Yoshihisa Yamaoka, Yoshinori Harada, Masaaki Sakakura, Takeo Minamikawa, Shigeru Nishino, Seiji Maehara, Shujiro Hamano, Hideo Tanaka and Tetsuro Takamatsu : Photoacoustic microscopy using ultrashort pulses with two different pulse durations., Optics Express, Vol.22, No.14, 17063-17072, 2014. (Summary) We propose photoacoustic microscopy using ultrashort pulses with two different pulse durations in the range from femtoseconds to picoseconds. The subtraction of images for longer-pulse excitation from those for shorter-pulse excitation extracts two-photon photoacoustic images effectively, based on observation that the intensity ratio of two-photon to one-photon absorption-induced photoacoustic signals depends on the pulse duration in the same manner as the intensity ratio of two-photon and one-photon fluorescence signals. Two-photon photoacoustic microscopy using this subtraction method enables precise observation of the cross-sections of silicone hollows filled with the mixture of one-photon and two-photon absorption solutions. (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.22.017063 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 25090520 ● Summary page in Scopus @ Elsevier: 2-s2.0-84904316954 (DOI: 10.1364/OE.22.017063, PubMed: 25090520, Elsevier: Scopus)
67.	Nanae Nishiki-Muranishi, Yoshinori Harada, Takeo Minamikawa, Yoshihisa Yamaoka, Ping Dai, Hitoshi Yaku and Tetsuro Takamatsu : Label-free evaluation of myocardial infarction and its repair by spontaneous Raman spectroscopy., Analytical Chemistry, Vol.86, No.14, 6903-6910, 2014. (Summary) Raman spectroscopy, which provides information about molecular species and structures of biomolecules via intrinsic molecular vibrations, can analyze physiological and pathological states of tissues on the basis of molecular constituents without staining. In this study, we analyzed Raman spectra of myocardial infarction and its repair in rats using the hypothesis that the myocardium in the course of myocardial infarction and its repair could be recognized by spontaneous Raman spectroscopy on the basis of chemical changes in myocardial tissues. Raman spectra were acquired from unfixed frozen cross sections of normal and infarcted heart tissues upon excitation at 532 nm. Raman spectra of the infarcted tissues were successfully obtained at characteristic time points: days 2, 5, and 21 after coronary ligation, at which the main components of the infarcted region were coagulation necrosis, granulation tissue, and fibrotic tissue, respectively. The latent variable weights calculated by a multivariate classification method, partial least-squares-discriminant analysis (PLS-DA), revealed fundamental information about the spectral differences among the types of tissues on the basis of molecular constituents. A prediction model for the evaluation of these tissue types was established via PLS-DA. Cross-validated sensitivities of 99.3, 95.3, 96.4, and 91.3% and specificities of 99.4, 99.5, 96.5, and 98.3% were attained for the discrimination of normal, necrotic, granulation, and fibrotic tissue, respectively. A two-dimensional image of a marginal area of infarction was successfully visualized via PLS-DA. Our results demonstrated that spontaneous Raman spectroscopy combined with PLS-DA is a novel label-free method of evaluating myocardial infarction and its repair. (Keyword) Animals / Female / Image Processing, Computer-Assisted / Least-Squares Analysis / Myocardial Infarction / Myocardium / Myocytes, Cardiac / Rats, Wistar / Reference Values / Spectrum Analysis, Raman (Link to Publication Site) ● Publication site (DOI): 10.1021/ac500592y (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24914734 ● Search Scopus @ Elsevier (PMID): 24914734 ● Search Scopus @ Elsevier (DOI): 10.1021/ac500592y (DOI: 10.1021/ac500592y, PubMed: 24914734)
68.	Kenichi Harada, Yoshinori Harada, Masatomo Beika, Noriaki Koizumi, Koji Inoue, Yasutoshi Murayama, Yoshiaki Kuriu, Masayoshi Nakanishi, Takeo Minamikawa, Yoshihisa Yamaoka, Ping Dai, Akio Yanagisawa, Eigo Otsuji and Tetsuro Takamatsu : Detection of lymph node metastases in human colorectal cancer by using 5-aminolevulinic acid-induced protoporphyrin IX fluorescence with spectral unmixing., International Journal of Molecular Sciences, Vol.14, No.11, 23140-23152, 2013. (Summary) Accurate evaluation of metastatic lymph nodes (LNs) is indispensable for adequate treatment of colorectal cancer (CRC) patients. Here, we demonstrate detection of metastases of human CRC in removed fresh LNs using 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) fluorescence. A spectral unmixing method was employed to reduce the overlap of collagen autofluorescence on PpIX fluorescence. A total of 17 surgery patients with advanced CRC were included in this study. After 5-ALA at a dose of 15 mg/kg of body weight was applied orally 2 h prior to surgery, 87 LNs were subjected to spectral fluorescence imaging and histopathological diagnosis, and statistical analysis was performed. No apparent side effect was observed to be associated with 5-ALA administration. The spectral unmixing fluorescence intensity of PpIX in metastatic LNs was 10.2-fold greater than that in nonmetastaic LNs. The receiver-operating-characteristic (ROC) analysis showed that the area under the curve (AUC) was calculated as 0.95. Our results show the potential of 5-ALA-induced PpIX fluorescence processed by spectral unmixing for detecting metastases in excised fresh LNs from patients with CRC, suggesting that this rapid and feasible method is applicable to gross evaluation of resected LN samples in pathology laboratories. (Keyword) Adult / Aged / Aged, 80 and over / Aminolevulinic Acid / Colorectal Neoplasms / Female / Fluorescence / Humans / Lymph Nodes / Lymphatic Metastasis / Male / Middle Aged / Protoporphyrins (Link to Publication Site) ● Publication site (DOI): 10.3390/ijms141123140 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24284403 ● Search Scopus @ Elsevier (PMID): 24284403 ● Search Scopus @ Elsevier (DOI): 10.3390/ijms141123140 (DOI: 10.3390/ijms141123140, PubMed: 24284403)
69.	Harsono Cahyadi, Junichi Iwatsuka, Takeo Minamikawa, Hirohiko Niioka, Tsutomu Araki and Mamoru Hashimoto : Fast spectral coherent anti-Stokes Raman scattering microscopy with high-speed tunable picosecond laser., Journal of Biomedical Optics, Vol.18, No.9, 96009, 2013. (Summary) We develop a coherent anti-Stokes Raman scattering (CARS) microscopy system equipped with a tunable picosecond laser for high-speed wavelength scanning. An acousto-optic tunable filter (AOTF) is integrated in the laser cavity to enable wavelength scanning by varying the radio frequency waves applied to the AOTF crystal. An end mirror attached on a piezoelectric actuator and a pair of parallel plates driven by galvanometer motors are also introduced into the cavity to compensate for changes in the cavity length during wavelength scanning to allow synchronization with another picosecond laser. We demonstrate fast spectral imaging of 3T3-L1 adipocytes every 5 cm-1 in the Raman spectral region around 2850 cm-1 with an image acquisition time of 120 ms. We also demonstrate fast switching of Raman shifts between 2100 and 2850 cm-1, corresponding to CD2 symmetric stretching and CH2 symmetric stretching vibrations, respectively. The fast-switching CARS images reveal different locations of recrystallized deuterated and nondeuterated stearic acid. (Keyword) Adipocytes / Animals / Cell Line / Image Processing, Computer-Assisted / Lasers / Lipids / Mice / Microscopy / Spectrum Analysis, Raman (Link to Publication Site) ● Publication site (DOI): 10.1117/1.JBO.18.9.096009 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24013358 ● Search Scopus @ Elsevier (PMID): 24013358 ● Search Scopus @ Elsevier (DOI): 10.1117/1.JBO.18.9.096009 (DOI: 10.1117/1.JBO.18.9.096009, PubMed: 24013358)
70.	Takeo Minamikawa, Yoshinori Harada, Noriaki Koizumi, Koji Okihara, Kazumi Kamoi, Akio Yanagisawa and Tetsuro Takamatsu : Label-free detection of peripheral nerve tissues against adjacent tissues by spontaneous Raman microspectroscopy., Histochemistry and Cell Biology, Vol.139, No.1, 181-193, 2013. (Summary) Detection of peripheral nerve tissues during surgery is required to avoid neural disturbance following surgery as an aspect of realizing better functional outcome. We provide a proof-of-principle demonstration of a label-free detection technique of peripheral nerve tissues, including myelinated and unmyelinated nerves, against adjacent tissues that employ spontaneous Raman microspectroscopy. To investigate the Raman spectral features of peripheral nerves in detail, we used unfixed sectioned samples. Raman spectra of myelinated nerve, unmyelinated nerve, fibrous connective tissue, skeletal muscle, tunica media of blood vessel, and adipose tissue of Wistar rats were analyzed, and Raman images of the tissue distribution were constructed using the map of the ordinary least squares regression (OLSR) estimates. We found that nerve tissues exhibited a specific Raman spectrum arising from axon or myelin sheath, and that the nerve tissues can be selectively detected against the other tissues. Moreover, myelinated and unmyelinated nerves can be distinguished by the intensity differences of 2,855 cm⁻¹, and 2,945 cm⁻¹, which are mainly derived from lipid and protein contents of nerve fibers. We applied this method to unfixed section samples of human periprostatic tissues excised from prostatic cancer patients. Myelinated nerves, unmyelinated nerves, fibrous connective tissues, and adipose tissues of the periprostatic tissues were separately detected by OLSR analysis. These results suggest the potential of the Raman spectroscopic observation for noninvasive and label-free nerve detection, and we expect this method could be a key technique for nerve-sparing surgery. (Keyword) Adipose Tissue / Animals / Connective Tissue / Humans / Image Interpretation, Computer-Assisted / Least-Squares Analysis / Male / Nerve Fibers, Myelinated / Nerve Fibers, Unmyelinated / Peripheral Nerve Injuries / Peripheral Nerves / Prostatectomy / Rats / Rats, Wistar / Spectrum Analysis, Raman / Tunica Media (Link to Publication Site) ● Publication site (DOI): 10.1007/s00418-012-1015-3 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22892663 ● Search Scopus @ Elsevier (PMID): 22892663 ● Search Scopus @ Elsevier (DOI): 10.1007/s00418-012-1015-3 (DOI: 10.1007/s00418-012-1015-3, PubMed: 22892663)
71.	Takeo Minamikawa, Hirohiko Niioka, Tsutomu Araki and Mamoru Hashimoto : Real-time imaging of laser-induced membrane disruption of a living cell observed with multifocus coherent anti-Stokes Raman scattering microscopy., Journal of Biomedical Optics, Vol.16, No.2, 021111-1-021111-5, 2011. (Summary) We demonstrate the real-time imaging of laser-induced disruption of the cellular membrane in a living HeLa cell and its cellular response with a multifocus coherent anti-Stokes Raman scattering (CARS) microscope. A near-infrared pulsed laser beam tightly focused on the cellular membrane of a living cell induces ablation at the focal point causing a local disruption of the cellular membrane. After the membrane disruption a dark spot decreasing CARS intensity of 2840 cm(-1) Raman shift at the disrupted site appears. This dark spot immediately disappears and a strong CARS signal is observed around the disrupted site. This increase of the CARS signal might be caused by resealing of the disrupted site via aggregation of the patch lipid vesicles in the cytoplasm. The accumulation of lipids around the disrupted site is also confirmed with three-dimensional CARS images of a cell before and after membrane disruption. The temporal behavior of the CARS signal at the disrupted site is observed to detect the fusion dynamics of patch vesicles. (Keyword) Animals / Cell Membrane / Computer Systems / Equipment Design / Equipment Failure Analysis / Lasers / Mice / Microscopy / Spectrum Analysis, Raman (Link to Publication Site) ● Publication site (DOI): 10.1117/1.3533314 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21361674 ● Search Scopus @ Elsevier (PMID): 21361674 ● Search Scopus @ Elsevier (DOI): 10.1117/1.3533314 (DOI: 10.1117/1.3533314, PubMed: 21361674)
72.	Takeo Minamikawa, Mamoru Hashimoto, Katsumasa Fujita, Satoshi Kawata and Tsutomu Araki : Multi-focus excitation coherent anti-Stokes Raman scattering (CARS) microscopy and its applications for real-time imaging., Optics Express, Vol.17, No.12, 9526-9536, 2009. (Summary) We developed a multi-focus excitation coherent anti-Stokes Raman scattering (CARS) microscope using a microlens array scanner for real-time molecular imaging. Parallel exposure of a specimen with light from two highly controlled picosecond mode-locked lasers (jitter of 30 fs through an electronic low-pass filter with 150 Hz bandwidth, point-by-point wavelength scan within 300 ms) and parallel detection with an image sensor enabled real-time imaging. We demonstrated real-time CARS imaging of polystyrene beads (frame rate of 30 fps), a giant multi-lamellar vesicle of dipalmitoylphosphatidylcholine (frame rate of 10 fps), and living HeLa cells (frame rate of 10 fps). (Keyword) Computer Systems / Computer-Aided Design / Equipment Design / Equipment Failure Analysis / Lenses / Microscopy, Video / Reproducibility of Results / Sensitivity and Specificity / Spectrum Analysis, Raman / Tomography, Optical Coherence (Link to Publication Site) ● Publication site (DOI): 10.1364/OE.17.009526 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 19506600 ● Search Scopus @ Elsevier (PMID): 19506600 ● Search Scopus @ Elsevier (DOI): 10.1364/OE.17.009526 (DOI: 10.1364/OE.17.009526, PubMed: 19506600)

Academic Paper (Unrefereed Paper):

1.	Takeo Minamikawa, Ogura Takashi, Masuoka Takashi, Eiji Hase, Yoshiaki Nakajima, Yamaoka Yoshihisa, Kaoru Minoshima and Takeshi Yasui : Optical-frequency-comb based ultrasound sensor, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10064, 100645C, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2250792 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85018866599 (DOI: 10.1117/12.2250792, Elsevier: Scopus)
2.	Kyuki Shibuya, Takeo Minamikawa, Yasuhiro Mizutani, Takeshi Yasui and Tetsuo Iwata : Hyperspectral single-pixel imaging with dual optical combs, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10076, 100761C, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2251250 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85020300077 (DOI: 10.1117/12.2251250, Elsevier: Scopus)
3.	Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Scan-less confocal phase imaging with dual comb microscopy, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10076, 100761C, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2251113 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85020292484 (DOI: 10.1117/12.2251113, Elsevier: Scopus)
4.	Eiji Hase, Takeo Minamikawa, Katsuya SATO, Daisuke Yonekura, Mitsuhiko Takahashi and Takeshi Yasui : Orientation analysis of collagen fibers in healing tendon by using second-harmonic-generation microscopy, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10069, 1006909, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2251111 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85020294503 (DOI: 10.1117/12.2251111, Elsevier: Scopus)
5.	Kosuke Atsuta, Yuki Ogura, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : In situ monitoring of collagen fibers in human skin using a photonic-crystal-fiber-coupled, hand-held, second-harmonic-generation microscope, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10069, 100692B, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2251321 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85020313109 (DOI: 10.1117/12.2251321, Elsevier: Scopus)
6.	Takeo Minamikawa, Yoshinori Harada and Tetsuro Takamatsu : Raman spectroscopic detection of peripheral nerves towards nerve-sparing surgery, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10054, 100541E, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2250807 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85018930329 (DOI: 10.1117/12.2250807, Elsevier: Scopus)
7.	Takeo Minamikawa, Hisataka Matsuo, Yoshiyuki Kato, Yoshinori Harada, Eigo Otsuji, Akio Yanagisawa, Hideo Tanaka and Tetsuro Takamatsu : Simple and optimum background-free estimation method of PPIX fluorescence for 5-ALA-based fluorescence diagnosis of malignant lesions, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10047, 100470S, 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2250780 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85019262322 (DOI: 10.1117/12.2250780, Elsevier: Scopus)

Academic Letter:

1.	Takeo Minamikawa, Tatsuro Takagi, Hirohiko Niioka, Makoto Kurihara, Nobuyuki Hashimoto, Tsutomu Araki and Mamoru Hashimoto : Molecular orientation imaging of liquid crystals by tunable-polarization-mode coherent anti-Stokes Raman scattering microscopy, Applied Physics Express, Vol.6, No.7, 072401, 2013. (Summary) We have developed a tunable-polarization-mode coherent anti-Stokes Raman scattering (CARS) microscope with compact polarization mode converters constructed using eight-segmented liquid-crystal spatial light modulators. The polarization modes, such as linear, radial, and azimuthal polarizations, of two excitation beams are controlled independently and are switched without any mechanical tuning in less than 300 ms. We use the system to detect the molecular orientation of 4-cyano-4'-octylbiphenyl (8CB) liquid crystals aligned parallel and perpendicular to the optical axis. We also observe CARS images of liquid crystal defects known as focal conic domains, demonstrating the potential of our molecular orientation imaging system. (C) 2013 The Japan Society of Applied Physics (Keyword) configuration light (Link to Publication Site) ● Publication site (DOI): 10.7567/APEX.6.072401 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84880822143 (DOI: 10.7567/APEX.6.072401, Elsevier: Scopus)
2.	Takeo Minamikawa, Naoki Tanimoto, Mamoru Hashimoto, Tsutomu Araki, Minoru Kobayashi, Katsumasa Fujita and Satoshi Kawata : Jitter reduction of two synchronized picosecond mode-locked lasers using balanced cross-correlator with two-photon detectors, Applied Physics Letters, Vol.89, No.19, 191101, 2006. (Summary) The authors have developed a highly synchronized picosecond mode-locked laser system. A balanced cross-correlator using two-photon detectors was employed to observe femtosecond order timing jitter between two picosecond lasers (1.26 fs with 150 Hz bandwidth and 7.14 fs with 1 kHz bandwidth), and a signal from the correlator was used as a feedback control signal to reduce the timing jitter. The timing jitter between the two lasers was reduced to 8 fs through a low-pass filter with 150 Hz bandwidth. (Keyword) Coherent anti-Stokes Raman scattering microscopy Jitter reduction Two-photon detector Balanced cross-correlator (Link to Publication Site) ● Publication site (DOI): 10.1063/1.2374803 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-33750901530 (DOI: 10.1063/1.2374803, Elsevier: Scopus)

Review, Commentary:

1.	Takeshi Yasui, Takeo Minamikawa, Yu Tokizane, Naoya Kuse, Takaaki Koma, Takao Ueda and Masako Nomaguchi : 目に見えない光が切り拓く『光の世紀』, Journal of the Japan Society for Precision Engineering, Vol.89, No.8, 587-591, Aug. 2023. (Link to Publication Site) ● Publication site (DOI): 10.2493/jjspe.89.587 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.2493/jjspe.89.587 (DOI: 10.2493/jjspe.89.587)
2.	Takeo Minamikawa : ラマン分光法による非侵襲生体分子機能診断, The Cell, Vol.54, No.13, 12-15, Dec. 2022.
3.	Takeo Minamikawa : 深紫外LEDを用いた新型コロナウイルス不活化, 光技術動向調査報告書, 31-34, Apr. 2022.
4.	Takeo Minamikawa : ラマン分光法の病理学への応用∼病理学に新しい視点を提供する∼, Optical Alliance, Vol.33, No.6, 36-40, Apr. 2022. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520855375009524608 (CiNii: 1520855375009524608)
5.	Eiji Hase, Takeo Minamikawa, Takahiko Mizuno and Takeshi Yasui : 空間/波長次元変換を用いたワンショット共焦点顕微鏡の高度化∼ポスト光増幅による測定の高速化および蛍光イメージングへの応用∼, 検査技術, Vol.27, No.3, 1-10, Mar. 2022. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1522543656133616768 (CiNii: 1522543656133616768)
6.	Takeo Minamikawa : ラマン分光法の医学への展開, The Review of Laser Engineering, Vol.50, No.2, 77-81, Feb. 2022. (Keyword) Raman spectroscopy / Medical application / Myocardial infarction / Non-alcoholic fatty liver disease (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1521417756226803968 (CiNii: 1521417756226803968)
7.	Takeo Minamikawa : ラマン散乱分光法の病理学への応用∼病理学に新しい価値観を創造する可視化技術∼, Optical and Electro-Optical Engineering Contact, Vol.59, No.10, 28, Oct. 2021. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1523669556025866752 (CiNii: 1523669556025866752)
8.	Takeo Minamikawa, Takaaki Koma, Suzuki Akihiro, Kentaro Nagamatsu, Takeshi Yasui, Koji Yasutomo and Masako Nomaguchi : Inactivation of SARS-CoV-2 by deep ultraviolet light emitting diode: A review, Japanese Journal of Applied Physics, Vol.60, No.9, 090501, Aug. 2021. (Link to Publication Site) ● Publication site (DOI): 10.35848/1347-4065/ac19d1 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.35848/1347-4065/ac19d1 (DOI: 10.35848/1347-4065/ac19d1)
9.	Takeo Minamikawa, Takaaki Koma, 鈴木昭浩, Kentaro Nagamatsu, Takeshi Yasui, Koji Yasutomo and Masako Nomaguchi : Withコロナ時代に向けた深紫外LEDの活用法, クリーンテクノロジー, Vol.31, No.6, 1-5, Jun. 2021. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520857063623582336 (CiNii: 1520857063623582336)
10.	Takeo Minamikawa, Takaaki Koma, 鈴木昭浩, Kentaro Nagamatsu, Takeshi Yasui, Koji Yasutomo and Masako Nomaguchi : 深紫外LEDによる新型コロナウイルス不活化への試み, OPTRONICS, Vol.40, No.6, 132-137, May 2021.
11.	Takeo Minamikawa, Takaaki Koma, 鈴木昭浩, Kentaro Nagamatsu, Takeshi Yasui, Koji Yasutomo and Masako Nomaguchi : 深紫外LEDを用いた新型コロナウイルスの不活化, O plus E, Vol.43, No.2, 137-142, Mar. 2021. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1521699231001747584 (CiNii: 1521699231001747584)
12.	Takeshi Yasui, Eiji Hase, Takahiko Mizuno, Ryo Oe and Takeo Minamikawa : 光周波数コム(光コム)の新奇特徴に基づいた知的光計測, The Journal of the Institute of Electronics, Information and Communication Engineers, Vol.103, No.11, 1126-1131, Nov. 2020. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520290884200033536 (CiNii: 1520290884200033536)
13.	Ryo Oe, Takeo Minamikawa and Takeshi Yasui : 光コムを用いた新たなファイバーセンサー, Optical and Electro-Optical Engineering Contact, Vol.58, No.8, 9-18, Jul. 2020. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1523106605684929408 (CiNii: 1523106605684929408)
14.	Takuya Tsuda, Takahiko Mizuno, Eiji Hase, Kazuki Nitta, Hidenori Koresawa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : スキャンレス・デュアル光コム顕微鏡を用いた動体サンプルのイメージング, Optical Alliance, Vol.30, No.6, 11-14, Jun. 2020. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1523106603356335616 (CiNii: 1523106603356335616)
15.	Takeo Minamikawa : 術中医療診断を目指したラマン散乱分光法~分子振動に基づく新たな無染色組織分子診断法~, Journal of the Spectroscopical Society of Japan, Vol.68, No.4, 142-149, Nov. 2019.
16.	Eiji Hase, Takeo Minamikawa, Takahiko Mizuno, Hirotsugu Yamamoto and Takeshi Yasui : スキャンレスデュアルコム顕微鏡による共焦点位相イメージング, JAPANESE JOURNAL OF OPTICS, Vol.48, No.11, 462-468, Nov. 2019.
17.	Eiji Hase, Takeo Minamikawa, Takahiko Mizuno, Katsuya SATO, Yoshiaki Nakajima, 浅原彰文, Kaoru Minoshima, Yasuhiro Mizurani, Tetsuo Iwata, Hirotsugu Yamamoto and Takeshi Yasui : スキャンレス光コム顕微鏡~光コムを用いたスキャンレス共焦点位相イメージング~, JAPANESE JOURNAL OF OPTICS, Vol.48, No.6, 227, Jun. 2019.
18.	Masatomo Yamagiwa, Takeo Minamikawa, Takeshi Yasui, 諸橋功 and Hirotsugu Yamamoto : モード操作GHz光コムを用いたマルチ合成波長デジタルホログラフィ, Optical and Electro-Optical Engineering Contact, Vol.57, No.3, 24-32, Mar. 2019.
19.	Takeo Minamikawa, Takeshi Yasui, Eiji Hase and Hirotsugu Yamamoto : 空間/波長次元変換を用いたワンショット共焦点顕微鏡, 検査技術, Vol.23, No.11, 6-12, Nov. 2018.
20.	Masatomo Yamagiwa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Cascade-Linked Multiple-Synthetic-Wavelength Digital Holography Using Optical Frequency Synthesizer, The Review of Laser Engineering, Vol.46, No.7, 370-373, Jul. 2018. (Summary) We present multiple-synthetic-wavelength digital holography using an optical frequency synthesizer (OFS) phaselocked to an optical frequency comb. The cascaded links of multiple synthetic wavelengths and a single optical wavelength generated by an OFS enable 3D shape measurements with a wide axial dynamic range and high-axial resolution. We demonstrate the shape measurements of a 1-mm step surface with an axial precision of a few tens of nm by cascading five synthesized wavelengths and a single optical wavelength. (Keyword) Digital holography / Optical frequency synthesizer, / Optical frequency comb / Synthetic wavelength (Link to Publication Site) ● Publication site (DOI): 10.2184/lsj.46.7_370 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1391412881267554688 ● Search Scopus @ Elsevier (DOI): 10.2184/lsj.46.7_370 (DOI: 10.2184/lsj.46.7_370, CiNii: 1391412881267554688)
21.	Takeo Minamikawa, Yi-Da Hsieh, Kyuki Shibuya, Eiji Hase, Yoshiki Kaneoka, Sho Okubo, Hajime Inaba, Yasuhiro Mizurani, Hirotsugu Yamamoto, Tetsuo Iwata and Takeshi Yasui : Dual-comb spectroscopic ellipsometry, JAPANESE JOURNAL OF OPTICS, Vol.47, No.6, 242, Jun. 2018.
22.	Takeo Minamikawa : 若手研究者の挑戦第30回:光コムを用いた精密計測と顕微イメージングへの応用, OPTRONICS, Vol.37, No.6, 130-136, Jun. 2018. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520291854764290816 (CiNii: 1520291854764290816)
23.	Takeo Minamikawa, Sho Okubo, Hajime Inaba, Tetsuo Iwata and Takeshi Yasui : 光コムを用いた分光エリプソメトリー法, Optical Alliance, Vol.29, No.5, 53-58, May 2018. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1521136280613856512 (CiNii: 1521136280613856512)
24.	Takeo Minamikawa, Eiji Hase, Shuji Miyamoto, Hirotsugu Yamamoto and Takeshi Yasui : 波長分散素子を用いたワンショット共焦点顕微鏡, ケミカルエンジニヤリング, Vol.63, No.3, 28-35, Mar. 2018.
25.	Kyuki Shibuya, Takeo Minamikawa, Takeshi Yasui and Tetsuo Iwata : 光コムを用いたスキャンレス超高密度ハイパースペクトルイメージング -デュアルコム分光とシングル・ピクセル・イメージングの融合-, OPTRONICS, Vol.36, No.10, 81-86, Oct. 2017.
26.	Eiji Hase, Shuji Miyamoto, Tatsushi Ichikawa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : スペクトル・エンコーディングを用いたラインフィールド共焦点デュアル光コム顕微鏡, The Review of Laser Engineering, Vol.45, No.6, 324-327, Jun. 2017.
27.	Takeo Minamikawa, Yoshinori Harada and Tetsuro Takamatsu : 術中応用を目指したラマン散乱分光法~分子振動に基づく医療センシングの可能性~, Optical Alliance, Vol.28, No.5, 42-47, May 2017.
28.	Takeshi Yasui, Shuji Miyamoto, Eiji Hase, Takeo Minamikawa and Hirotsugu Yamamoto : ライン集光スリットと波長-空間変換を用いたスキャンレス・フルフィールド共焦点レーザー顕微鏡, Optical Alliance, Vol.27, No.11, 10-13, Nov. 2016.
29.	Eiji Hase, Takeo Minamikawa, Takahiko Mizuno, Katsuya SATO, Yoshiaki Nakajima, 浅原彰文, Kaoru Minoshima, Yasuhiro Mizurani, Tetsuo Iwata, Hirotsugu Yamamoto and Takeshi Yasui : 光コムを用いたスキャンレス共焦点位相イメージング, JAPANESE JOURNAL OF OPTICS, Vol.48, No.6, 227, Jun. 2016.
30.	Noriaki Koizumi, Yoshinori Harada, Takeo Minamikawa, Hideo Tanaka, Eigo Otsuji and Tetsuro Takamatsu : Recent advances in photodynamic diagnosis of gastric cancer using 5-aminolevulinic acid., World Journal of Gastroenterology : WJG, Vol.22, No.3, 1289-1296, Jan. 2016. (Summary) Photodynamic diagnosis based on 5-aminolevulinic acid-induced protoporphyrin IX has been clinically applied in many fields based upon its evidenced efficacy and adequate safety. In order to establish a personalized medicine approach for treating gastric cancer patients, rapid intraoperative detection of malignant lesions has become important. Feasibility of photodynamic diagnosis using 5-aminolevulinic acid for gastric cancer patients has been investigated, especially for the detection of peritoneal dissemination and lymph node metastasis. This method enables intraoperative real-time fluorescence detection of peritoneal dissemination, exhibiting higher sensitivity than white light observation without histopathological examination. The method also enables detection of metastatic foci within excised lymph nodes, exhibiting a diagnostic accuracy comparable to that of a current molecular diagnostics technique. Although several complicating issues still need to be resolved, such as the effect of tissue autofluorescence and the insufficient depth penetration of excitation light, this simple and rapid method has the potential to become a useful diagnostic tool for gastric cancer, as well as urinary bladder cancer and glioma. (Tokushima University Institutional Repository) ● Metadata: 114499 (Link to Publication Site) ● Publication site (DOI): 10.3748/wjg.v22.i3.1289 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26811665 ● Summary page in Scopus @ Elsevier: 2-s2.0-84956467587 (Tokushima University Institutional Repository: 114499, DOI: 10.3748/wjg.v22.i3.1289, PubMed: 26811665, Elsevier: Scopus)
31.	原田義規, Takeo Minamikawa and 高松哲郎 : ラマン分光法による生体情報の可視化, OPTRONICS, Vol.33, No.389, 70-73, 2014.
32.	橋本守, Harsono Cahyadi, 新岡宏彦, Tsutomu Araki and Takeo Minamikawa : 多焦点リアルタイムCARS顕微鏡による細胞応答観測, OPTRONICS, Vol.33, No.389, 74-78, 2014.
33.	Takeo Minamikawa, 原田義規 and 髙松哲郎 : ラマン散乱顕微鏡による分子イメージング, Optical Alliance, Vol.25, No.3, 21-25, 2014.
34.	原田義規, Takeo Minamikawa and 髙松哲郎 : 光を利用した非標識生体分子イメージング, G.I. Research, Vol.22, No.1, 44-49, 2014.
35.	Takeo Minamikawa, 原田義規 and 髙松哲郎 : 無染色組織イメージング~ラマン散乱分光法を用いて~, 京都府立医科大学雑誌, Vol.122, No.4, 209-217, 2013.
36.	Mamoru Hashimoto, Takeo Minamikawa and Tsutomu Araki : Coherent anti-stokes Raman scattering microscopy for high speed non- staining biomolecular imaging., Current Pharmaceutical Biotechnology, Vol.14, No.2, 150-158, 2013. (Summary) Vibrational microscopy (Raman microscopy and infrared microscopy), which observes molecular vibrations, gives us the information of molecular species without staining because the observed signals are originated from intrinsic molecules of a cell. However, infrared radiation is absorbed with water, and the long wavelength (3-10 m) limits the spatial resolution to several micrometers. Spontaneous emission of Raman scattering is quite feeble, and the Raman scattering often overlaps with one-photon fluorescence from a specimen. Coherent anti-Stokes Raman scattering (CARS) microscopy, which is one of the nonlinear Raman microscopy, is a method to overcome those problems. In this review, present system of CARS microscopy, the methods of background rejection, and applications are introduced. (Keyword) Artifacts / Light / Microscopy / Molecular Imaging / Optical Imaging / Spectrum Analysis, Raman (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22356111 ● Search Scopus @ Elsevier (PMID): 22356111 (PubMed: 22356111)
37.	橋本守, Takeo Minamikawa, 新岡宏彦 and Tsutomu Araki : リアルタイムCARS顕微鏡の開発と生細胞観測への応用, The Journal of Japan Society for Laser Surgery and Medicine, Vol.30, No.4, 421-426, 2010.
38.	Takeo Minamikawa, Tsutomu Araki and 橋本守 : 多焦点CARS顕微鏡によるリアルタイム分子イメージング, OPTRONICS, Vol.332, 103-107, 2009.

Proceeding of International Conference:

1.	Yudai Matsumura, Eiji Hase, Yu Tokizane, Naoya Kuse, Takeo Minamikawa, Junichi Fujikata, Hiroki Kishikawa, Masanobu Haraguchi, Yasuhiro Okamura, Kaji Takahiro, Otomo Akira, Kanno Atsushi, Hisatake Shintaro and Takeshi Yasui : Dual-wavelength CW lasers injection-locked to optical comb modes for carrier conversion from THz wave to near-infrared light via electro-optical polymer modulator, 48th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz2023), Th-P2-63, Montreal, Sep. 2023.
2.	Shogo Miyamura, Ryo Oe, Takuya Nakahara, Shuji Taue, Yu Tokizane, Takeo Minamikawa, Taira Kajisa and Takeshi Yasui : Dual-comb biosensing of SARS-CoV-2 nucleocapsid protein antigen, The 12th Asia-Pacific Laser Symposium (APLS 2023), HTh1-01, Hakodate, Sep. 2023.
3.	Tsuyoshi Takashina, Hayata Tadamasa, Katsuya SATO, Takeshi Yasui and Takeo Minamikawa : Molecular analysis of intracellular lipid droplets produced by fatty acid uptake by using Raman spectroscopy, The 12th Asia-Pacific Laser Symposium (APLS 2023), PGTu-07, Hakodate, Sep. 2023.
4.	Takeo Minamikawa, Sota Inoue, Sora Yamamoto, Taishi Amano, Akihiro Shiota, Shota Miyamoto, Takeshi Yasui, Masahiro Kawasaki and Mitsuo Kawasaki : Remote plasmonic-enhanced Raman spectroscopy for highly sensitive biosensing with high mechanical and chemical stabilities, The 12th Asia-Pacific Laser Symposium (APLS 2023), GTu2-02, Hakodate, Sep. 2023.
5.	Yuya Kodama, Hidenori Koresawa, Eiji Hase, Yu Tokizane, Takeo Minamikawa and Takeshi Yasui : Dual-comb spectroscopy of angular surface-plasmon-resonance spectrum using angle-converting optical frequency comb, Photonics and Electromagnetics Research Symposium (PIERS2023), 2A_13, Praha, Jul. 2023.
6.	Yuya Kodama, Hidenori Koresawa, Eiji Hase, Yu Tokizane, Takeo Minamikawa and Takeshi Yasui : Wavelength-to-angle conversion of optical frequency comb for dual-comb spectroscopy of angular-interrogation surface plasmon resonance, Conference on Lasers and Electro-Optics (CLEO) 2023, STh4K.5, San Jose, May 2023.
7.	Shogo Miyamura, Ryo Oe, Taira Kajisa, Yu Tokizane, Taue Shuji, Takeo Minamikawa and Takeshi Yasui : Temperature-compensated refractive index sensing using dual fiber comb, OPIC2023: ALPS2023, ALPS26-01, Yokohama, Apr. 2023.
8.	Shinpei Kajiwara, Takeo Minamikawa, Tomoya Okabe, Eiji Hase and Takeshi Yasui : Laser-scanning optical-frequency-comb microscopy for imaging using various aspects of light information, OPIC2023: BISC2023, BISC4-01, Yokohama, Apr. 2023.
9.	Tomoya Okabe, Keishiroh Ohtani, Shinpei Kaziwara, Eiji Hase, Takeshi Yasui and Takeo Minamikawa : Transmission stage scanning optical frequency comb microscopy for multi-optical-parameter evaluation, pLED International symposium 2023: Exploring Invisible Light Technology, P-29, Tokushima, Mar. 2023.
10.	Sota Inoue, Hiroki Tanioka, Takeshi Yasui, Yukihiro Morimoto, Mitsuo Kawasaki and Takeo Minamikawa : Fundamental characterization of remote plasmonic-enhanced Raman spectroscopy, pLED International symposium 2023: Exploring Invisible Light Technology, P-28, Tokushima, Mar. 2023.
11.	Yuya Kodama, Hidenori Koresawa, Eiji Hase, Yu Tokizane, Takeo Minamikawa and Takeshi Yasui : Observation of angular spectrum of surface plasmon resonance dip using wavelength-to-angle-conversion optical frequency comb, pLED International symposium 2023: Exploring Invisible Light Technology, P-18, Tokushima, Mar. 2023.
12.	Hiroki Kitahama, Akira Emoto, Akihiro Suzuki, Atsuo Ochi, Takeo Minamikawa, Rei Nakamura and Takeshi Yasui : Estimation procedure of UV sterilization effects for various UV light sources, pLED International symposium 2023: Exploring Invisible Light Technology, P-15, Tokushima, Mar. 2023.
13.	Kazuki Yasumaru, Mayuko Shimizu, Eiji Hase, Takeshi Yasui, Koichi Tsuneyama and Takeo Minamikawa : Raman and SHG spectroscopic analyses of lipid droplets accumulated in the liver of a mouse model of nonalcoholic fatty liver disease, pLED International symposium 2023: Exploring Invisible Light Technology, P-11, Tokushima, Mar. 2023.
14.	Tomohiro Tamaki, Takeo Minamikawa, Eiji Hase, Yuki Morimoto, Akihiro Suzuki, Takeshi Yasui, Satoko Nakamura, Akemi Tsutsui, Koichi Takagushi and Koichi Tsuneyama : Second-harmonic generation polarization microscopy to analyze ultra-early-stage liver fibrosis in human non-alcoholic fatty liver disease, pLED International symposium 2023: Exploring Invisible Light Technology, P-5, Tokushima, Mar. 2023.
15.	Koshiro Hori, Takeo Minamikawa, Yoshiki Terao, Masami Shishibori and Takeshi Yasui : Identification of spectral features for selective detection of peripheral nerves by support vector machine-based Raman spectral analysis, Proceedings of SPIE, Vol.112391, 112391-47, San Francisco, Jan. 2023.
16.	Hayata Tadamasa, Takeo Minamikawa, Akihiro Suzuki and Takeshi Yasui : Evaluation of lipid uptake in cells using Raman spectroscopy, Proceedings of SPIE, Vol.12391, 12391-66, San Francisco, Jan. 2023.
17.	Shogo Miyamura, ryo Oe, Takuya Nakahara, Shuji Taue, Yu Tokizane, Takeo Minamikawa, Taira Kajisa and Takeshi Yasui : Dual-comb biosensing of SARS-CoV-2 nucleocapsid protein antigen, Proceedings of SPIE, Vol.12372, 12372-16, San Francisco, Jan. 2023. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2651247 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85152768893 (DOI: 10.1117/12.2651247, Elsevier: Scopus)
18.	Eiji Hase, Takeo Minamikawa, Yu Tokizane and Takeshi Yasui : Analysis of lipid molecular properties in nonalcoholic fatty liver disease by use of Brillouin microspectroscopy, SPIE Biomedical Imaging and Sensing Conference 2022 (BISC2022), 250268, Taipei, Dec. 2022.
19.	Shogo Miyamura, Ryo Oe, Takuya Nakahara, Shota Okada, Shuji Taue, Yu Tokizane, Takeo Minamikawa, Taka-aki Yano, Kunihiro Otsuka, Ayuko Sakane, Takuya Sasaki, Koji Yasutomo, Taira Kajisa and Takeshi Yasui : Rapid detection of SARS- CoV-2 nucleocapsid protein antigen by dual- comb biosensing, SPIE Biomedical Imaging and Sensing Conference 2022 (BISC2022), 250308, Taipei, Dec. 2022.
20.	Takeo Minamikawa : Optical-frequency-comb microscopy for imaging with amplitude and phase of light wave, 25th Congress of the International Commission for Optics (ICO-25), 16th International Conference on Optics Within Life Sciences (OWLS-16), PO-33, Dresden, Sep. 2022.
21.	Kazuki Sadahiro, Yu Tokizane, Eiji Hase, Takeo Minamikawa, Isao Morohashi and Takeshi Yasui : Wavelength-scanning digital holography based on line-by-line spectrally shaping optical frequency comb, 25th Congress of the International Commission for Optics (ICO-25), PO-33, Dresden, Sep. 2022.
22.	Hidenori Koresawa, Eiji Hase, Yu Tokizane, Takeo Minamikawa and Takeshi Yasui : Measurement of Jones-matrix using dual-comb spectroscopic polarimetry, 25th Congress of the International Commission for Optics (ICO-25), PO-21, Dresden, Sep. 2022.
23.	Takeo Minamikawa : Inactivation of novel coronavirus by deep UV light, RadTech Asia 2022, Ibaraki, Aug. 2022.
24.	Hayata Tadamasa, Takeo Minamikawa, Yoshiki Terao, Koshirou Hori and Takeshi Yasui : PCA and Raman spectroscopy for discrimination of biological tissues and estimation of the basis for discrimination, 15th Pacific Rim Conference on Lasers and Electro-Optics 2022 (CLEO-PR2022), CThA15E-02, Sapporo, Aug. 2022. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEOPR.2022.CThA15E_02 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85166488433 (DOI: 10.1364/CLEOPR.2022.CThA15E_02, Elsevier: Scopus)
25.	Kazuki Sadahiro, Yu Tokizane, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : Development of mode-extracting optical frequency comb for rapid wavelength-scanning digital holography, 15th Pacific Rim Conference on Lasers and Electro-Optics 2022 (CLEO-PR2022), P-CTh6-10, Sapporo, Aug. 2022. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEOPR.2022.P_CTh6_10 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85166471309 (DOI: 10.1364/CLEOPR.2022.P_CTh6_10, Elsevier: Scopus)
26.	Hidenori Koresawa, Eiji Hase, Yu Tokizane, Takeo Minamikawa and Takeshi Yasui : Combination of dual-comb spectroscopy with Jones-matrix polarimetry, 15th Pacific Rim Conference on Lasers and Electro-Optics 2022 (CLEO-PR2022), P-CTh6-09, Sapporo, Aug. 2022. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEOPR.2022.P_CTh6_09 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85166472034 (DOI: 10.1364/CLEOPR.2022.P_CTh6_09, Elsevier: Scopus)
27.	Shogo Miyamura, Ryo Oe, Taira Kajisa, Yu Tokizane, Takeo Minamikawa, 田上周路 and Takeshi Yasui : Active-dummy compensation of temperature drift in refractive-index-sensing optical comb by use of mechanically-sharing dual-comb configuration, 15th Pacific Rim Conference on Lasers and Electro-Optics 2022 (CLEO-PR2022), P-CTh6-08, Sapporo, Aug. 2022. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEOPR.2022.P_CTh6_08 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85166474330 (DOI: 10.1364/CLEOPR.2022.P_CTh6_08, Elsevier: Scopus)
28.	Kohta Seki, Hidenori Koresawa, Eiji Hase, Yu Tokizane, Takeo Minamikawa, Taka-aki Yano, Taira Kajisa and Takeshi Yasui : Beam-angle-scanning surface plasmon resonance sensor, Optica Imaging and Applied Optics Congress 2022, JTu2A.6, Vancouver, Jul. 2022. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85139153703 (Elsevier: Scopus)
29.	MIYAMURA Shogo, Ryo Oe, Taira Kajisa, 田上周路, Takeo Minamikawa, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : Reduction of temperature frift in tefractive-index-sensing optical frequency comb by mechanical-sharing dual-fiber-cavity configuration, Conference on Lasers and Electro-Optics 2022 (CLEO2022), JTh3A.26, San Jose, May 2022.
30.	MIYAMURA Shogo, Ryo Oe, Takuya Nakahara, Shota Okada, Taira Kajisa, Shuji Taue, Yu Tokizane, Takeo Minamikawa, Taka-aki Yano, Kunihiro Otsuka, Ayuko Sakane, Takuya Sasaki, Koji Yasutomo and Takeshi Yasui : Dual-Comb Biosensing for Rapid Detection of SARS-CoV-2, Conference on Lasers and Electro-Optics 2022 (CLEO2022), JTh6A.6, San Jose, May 2022. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85139913953 (Elsevier: Scopus)
31.	Takeo Minamikawa : Quantitative evaluation of SARS-CoV-2 inactivation using DUV-LEDs, International Conference on Electronics Packaging (ICEP 2022), Sapporo, May 2022.
32.	Takeo Minamikawa : Molecular functional imaging by Raman spectroscopy towards medical application, International Meet & Expo on Laser, Optics, and Photonics (OPTICSMEET2021), Nice, France/Online (Hybrid), Nov. 2021.
33.	Takuya Nakahara, Ryo Oe, Taira Kajisa, Shuji Taue, Takeo Minamikawa and Takeshi Yasui : Application of refractive-index-sensing optical frequency comb for biosensing of antigen-antibody reaction, Conference on Lasers and Electro-Optics (CLEO) 2021, Technical Digest (online), STu2A, Online, May 2021. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEO_SI.2021.STu2A.2 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85120454099 (DOI: 10.1364/CLEO_SI.2021.STu2A.2, Elsevier: Scopus)
34.	Takuya Nakahara, Oe Ryo, Takeo Minamikawa, Taue Shuji, Taira Kajisa and Takeshi Yasui : Fiber biosensor based on a combination of refractive-index-sensing optical comb with chemical surface modification, BiOS2021 in Photonics West 2021, 11635-11618, Online, Mar. 2021. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2583197 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1117/12.2583197 (DOI: 10.1117/12.2583197)
35.	Hidenori Koresawa, Marc Gouryeb, Kyuki Shibuya, Takahiko Mizuno, Eiji Hase, Yu Tokizane, Ryo Oe, Takeo Minamikawa and Takeshi Yasui : Dual-comb spectroscopic polarimetry for dynamic characterization of polarization property, Proc. SPIE, Vol.11671, 116710H, Online, Mar. 2021. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2583107 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85107199786 (DOI: 10.1117/12.2583107, Elsevier: Scopus)
36.	Takeo Minamikawa : Optical-frequency-comb microscopy for multivariate spectroscopic imaging utilizing amplitude and phase information, International Symposium on Imaging, Sensing, and Optical Memory (ISOM'20), Takamatsu, Nov. 2020.
37.	Takuya Nakahara, Ryo Oe, Takeo Minamikawa, Shuji Taue, Taira Kajisa and Takeshi Yasui : Intra-cavity biosensing in refractive- index-sensing optical comb, 14th Pacific Rim Conference on Lasers and Electro-Optics (CLEO PR 2020), Online, Aug. 2020.
38.	Takuya Nakahara, Ryo Oe, Taira Kajisa, Shuji Taue, Takeo Minamikawa and Takeshi Yasui : Refractive-index-sensing optical comb using intra-cavity multi-mode-interference fiber sensor and its application for bio-sensing, OSA Optical Sensors and Sensing, JTu2A.23, Online, Jun. 2020. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85118610135 (Elsevier: Scopus)
39.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Scan-less full-field fluorescence lifetime imaging by 2D spectral encoding and dual-comb heterodyne-beating, Conference on Lasers and Electro-Optics (CLEO) 2020, STu4N.5, Online, May 2020. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85091627420 (Elsevier: Scopus)
40.	Takeo Minamikawa : (Invited) Optical-frequency-comb microscopy for spatio-temporal imaging with comprehensive optical information, The 9th Advanced Lasers and Photon Sources (ALPS2020), Online, Apr. 2020.
41.	Hiroki Takanari, Y Hayashi, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : Quantification of liver fibrosis by SHG microscopy., Focus on Microscopy 2020, Osaka, Apr. 2020.
42.	Eiji Hase, Hiroki Takanari, Mayuko Shimizu, Hayashi Yuri, Takeo Minamikawa, Takeshi Yasui and Koichi Tsuneyama : Characterization of fibrosis in non-alcoholic steatohepatitis by use of second-harmonic-generation microscopy, Asian Pacific Association for the Study of the Liver 2020 (APASL 2020), Bali, Indonesia, Mar. 2020.
43.	Takeo Minamikawa, Mayuko Shimizu, Hiroki Takanari, Shiomi Ryosuke, Kusaka Hiroki, Tanioka Hiroki, Eiji Hase, Takeshi Yasui and Koichi Tsuneyama : Molecular imaging analysis of accumulated fats in non-alcoholic steatohepatitis by Raman microscopy, Asian Pacific Association for the Study of the Liver 2020 (APASL 2020), Bali, Indonesia, Mar. 2020.
44.	Takeo Minamikawa, nakano shota, Eiji Hase, Asahara Akifumi, hidenori koresawa, Takahiko Mizuno, Hirotsugu Yamamoto, Kaoru Minoshima and Takeshi Yasui : Optical-frequency-comb microscopy with laser-scanning configuration for simultaneous and spectroscopic amplitude, quantitative phase, and polarization imaging, Photonics West 2020: OPTO2020, 11287-30, San Francisco, Feb. 2020.
45.	Takahiko Mizuno, tsuda takuya, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Application of post optical amplification for scan-less confocal amplitude and phase imaging with dual-comb microscopy, Photonics West 2020: BiOS2020, 11250-41, San Francisco, Feb. 2020.
46.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Full-field dual-comb fluorescence lifetime microscopy, Photonics West 2020: BiOS2020, 11250-42, San Francisco, Feb. 2020.
47.	Eiji Hase, maeda kosuke, Takahiko Mizuno, Takeo Minamikawa and Takeshi Yasui : Effect of wavelength on polarization-resolved second-harmonic- generation microscopy in thick tissues, Photonics West 2020: BiOS2020, 112544-75, San Francisco, Feb. 2020.
48.	Takeo Minamikawa, Terao Yoshiki, Shiomi Ryosuke and Takeshi Yasui : Multivariate spectral analysis for identification of spectral features of peripheral nerves using Raman microspectroscopy, Quantitative BioImaging Conference (QBI 2020), Oxford, Jan. 2020.
49.	Oe Ryo, Takeo Minamikawa, Taue Shuji, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : Refractive index sensor based on a combination of optical frequency comb with intracavity multi-mode interference fiber sensor, (Oct. 1-4, 2019/Limassol, Cyprus)., 7th European Workshop on Optical Fibre Sensors (EWOFS19), Limassol, Oct. 2019.
50.	Tsuda Takuya, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Post-optical-amplification of confocal amplitude and phase images in scan-less confocal dual-comb microscopy, OSA Technical Digest of OSA Laser Congress, JM5A.49, Wien, Sep. 2019. (Link to Publication Site) ● Publication site (DOI): 10.1364/ASSL.2019.JM5A.49 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85086286905 (DOI: 10.1364/ASSL.2019.JM5A.49, Elsevier: Scopus)
51.	Takahiko Mizuno, Takuya Moriki, Masatomo Yamagiwa, Takeo Minamikawa and Takeshi Yasui : Full-field THz polarimetric imaging with THz quantum cascade laser and THz imager, 44th International Conference on Infrared Millimeter and Terahertz Waves, Po2-@, Paris, Sep. 2019. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85074713796 (Elsevier: Scopus)
52.	Chen Jie, Kazuki Nitta, Zhao Xin, Takahiko Mizuno, Takeo Minamikawa, Zheng Zheng and Takeshi Yasui : Combination of adaptive sampling terahertz dual-comb spectroscopy with a free-running single-cavity dual-comb fiber laser, 44th International Conference on Infrared Millimeter and Terahertz Waves, Po2-@, Paris, Sep. 2019. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85074722920 (Elsevier: Scopus)
53.	Shota Nakano, Takeo Minamikawa, Eiji Hase, Asahara Akifumi, Takahiko Mizuno, Hirotsugu Yamamoto, Kaoru Minoshima and Takeshi Yasui : Laser scanning dual optical-frequency-comb spectromicroscopy, CLEO/Europe-EQEC 2019, CH-10.2CHU, Munich, Jun. 2019.
54.	Ryosuke Shiomi, Takeo Minamikawa, Ryo Oe, Ittetsu Taniguchi, Takeshi Yasui and Hirofumi Ohta : Comparative analysis of cultivation method for matcha green tea leaves by label-free multimodal microspectroscopy, Proceedings of SPIE/OSA European Conferences on Biomedical Optics 2019, 11075-47, Munich, Jun. 2019.
55.	Takeo Minamikawa, Tsunehisa Yamamoto, Yoshinori Harada, Yoshihisa Yamaoka, Hideo Takana, Hitoshi Yaku and Tetsuro Takamatsu : Raman spectroscopic evaluation of human myocardial infarction, CLEO/Europe-EQEC 2019, Jun. 2019. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85074651180 (Elsevier: Scopus)
56.	Takahiko Mizuno, Takuya Tsuda, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Improvement of image quality in dual-comb microscopy by post-amplification of dual comb lights, Conference on Lasers and Electro-Optics (CLEO) 2019, Technical Digest (online), AF3K.4, San Jose, May 2019. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEO_AT.2019.AF3K.4 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85068144234 (DOI: 10.1364/CLEO_AT.2019.AF3K.4, Elsevier: Scopus)
57.	Hidenori Koresawa, Kyuki Shibuya, Akifumi Asahara, Takeo Minamikawa, Kaoru Minoshima and Takeshi Yasui : Combination of lock-in detection with dual-comb spectroscopy, Conference on Lasers and Electro-Optics (CLEO) 2019, Technical Digest (online),, JTh2A.101, San Jose, May 2019. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEO_AT.2019.JTh2A.101 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85068169707 (DOI: 10.1364/CLEO_AT.2019.JTh2A.101, Elsevier: Scopus)
58.	Jie Chen, Kuzuki Nitta, Xin Zhao, Takahiko Mizuno, Takeo Minamikawa, Zheng Zheng and Takeshi Yasui : Adaptive sampling terahertz dual-comb spectroscopy based on a free-running single-cavity dual- comb fiber laser, Conference on Lasers and Electro-Optics (CLEO) 2019,Technical Digest (online), STh1G.4, San Jose, May 2019. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEO_SI.2019.STh1G.4 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85068171982 (DOI: 10.1364/CLEO_SI.2019.STh1G.4, Elsevier: Scopus)
59.	Masatomo Yamagiwa, Takeo Minamikawa, Isao Morohashi, Norihiko Sekine, Iwao Hosako, Hirotsugu Yamamoto and Takeshi Yasui : Cascade-linked multi-synthetic-wavelength digital holography using line-by-line spectral shaping optical frequency comb, Conference on Lasers and Electro-Optics (CLEO) 2019, Technical Digest (online), SM2H.5, San Jose, May 2019. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEO_SI.2019.SM2H.5 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85068171867 (DOI: 10.1364/CLEO_SI.2019.SM2H.5, Elsevier: Scopus)
60.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Scan-less full-field fluorescence microscopy by using 2D spectral disperser and dual-comb optical beats, The 5th Biomedical Imaging and Sensing Conference, BISC-P-09, Yokohama, Apr. 2019. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85065707665 (Elsevier: Scopus)
61.	Takuya Tsuda, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Implementation of imaging post amplifier on scan-less confocal dual-comb mcroscope, The 5th Biomedical Imaging and Sensing Conference, BISC-P-14, Yokohama, Apr. 2019. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85065711407 (Elsevier: Scopus)
62.	Takeo Minamikawa, Eiji Hase, Takuya Tsuda, Takahiko Mizuno, Hirotsugu Yamamoto and Takeshi Yasui : Scan-less dual-comb microscopy for confocal amplitude and phase imaging, Focus on Microscopy 2019 (FOM2019), P1-D/10, London, Apr. 2019.
63.	Takeo Minamikawa : (Invited) Optical microscopy with optical-frequency-comb, The 5th Biomedical Imaging and Sensing Conference, Kanagawa, Apr. 2019.
64.	Takeo Minamikawa, Yamamoto Tsunehisa, Harada Yoshinori, Yamaoka Yoshihisa, Tanaka Hideo, Yaku Hitoshi and Takamatsu Tetsuro : Label-free evaluation of human myocardial infarction using Raman spectroscopy, Focus on Microscopy 2019 (FOM 2019), Apr. 2019.
65.	Masatomo Yamagiwa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Transmission phase imaging of optically opaque object using phase- shifting terahertz digital holography, Proceedings of SPIE, Vol.10917, 10917-79, San Francisco, Feb. 2019.
66.	Hidenori Koresawa, Kyuki Shibuya, Akifumi Asahara, Takeo Minamikawa, Kaoru Minoshima and Takeshi Yasui : Combination of lock-in detection with dual-comb spectroscopy, Proceedings of SPIE, Vol.10925, 10925-47, San Francisco, Feb. 2019. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2509619 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85067932304 (DOI: 10.1117/12.2509619, Elsevier: Scopus)
67.	Masatomo Yamagiwa, Takeo Minamikawa, Clément Trovato, Hirotsugu Yamamoto, Takeshi Yasui, Yusuke Kawahito, Ryo Oe, Kyuki Shibuya, Takahiko Mizuno, Emmanuel Abraham, Yasuhiro Mizutani, Tetsuo Iwata, Kaoru Minoshima and Dahi Abdelsalam G. Ibrahim : Wide axial dynamic range digital holography using multicascade-linked synthetic wavelengths and optical wavelength10944-39, Proceedings of SPIE, Vol.10944, 10944-39, San Francisco, Feb. 2019. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2509354 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85068062795 (DOI: 10.1117/12.2509354, Elsevier: Scopus)
68.	Ryo Oe, Takeo Minamikawa, Shuji Taue, Hideki Fukano, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : Simultaneous measurement of concentration and temperature in liquid sample using multi-mode interference fiber comb, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10872, 10872-40, San Francisco, Feb. 2019. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2509539 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85064881651 (DOI: 10.1117/12.2509539, Elsevier: Scopus)
69.	Takuya Sakaue, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : Polarization-resolved SHG microscopy based on continuous rotation of linear polarization with an electro-optic modulator, Proceedings of SPIE, Vol.10882, 10882-103, San Francisco, Feb. 2019.
70.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Scan-less fluorescence imaging using 2D frequency multiplexed illumination by dual-comb optical beat and 2D spectral disperser, Proceedings of SPIE, Vol.10889, 10889-4, San Francisco, Feb. 2019.
71.	Takuya Tsuda, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Scan-less confocal phase imaging of biological samples using dual- comb microscopy, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10889, 10889-47, Feb. 2019. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2509244 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85066119791 (DOI: 10.1117/12.2509244, Elsevier: Scopus)
72.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Scan-less fluorescence microscopy by Ccombination of dual-comb optical beats and 2D spectral disperser, KEIO Symposium on Microresonator Frequency Com, P2, Tokyo, Dec. 2018.
73.	Hidenori Koresawa, Kyuki Shibuya, Akifumi Asahara, Takeo Minamikawa, Kaoru Minoshima and Takeshi Yasui : Use of lock-in detection in dual-comb spectroscopy, OSA Technical Digest of Light, Energy and the Environment 2018, J2A.26, Singapore, Nov. 2018. (Link to Publication Site) ● Publication site (DOI): 10.1364/FTS.2018.JT2A.26 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85059507997 (DOI: 10.1364/FTS.2018.JT2A.26, Elsevier: Scopus)
74.	Takeshi Yasui and Takeo Minamikawa : Dual-comb spectroscopic ellipsometry, OSA Technical Digest of Light, Energy and the Environment 2018, FM2B, Singapore, Nov. 2018.
75.	Ryo Oe, Kohsuke Nagai, Takeo Minamikawa, Shuji Taue, Hideki Fukano, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : Multi-mode-interference fiber comb for refractive index sensing, 26th International Conference on Optical Fiber Sensors, TuE44, ローザンヌ, Sep. 2018.
76.	Kyuki Shibuya, Takeo Minamikawa, Yasuhiro Mizutani, Takeshi Yasui and Tetsuo Iwata : Dual-comb-spectroscopic single-pixel Imaging with high frequency resolution and accuracy, Progress In Electromagnetics Research Symposium (PIERS) 2018, Toyama, Aug. 2018.
77.	Takeo Minamikawa, Shota Nakano, Eiji Hase, Takahiko Mizuno, Hirotsugu Yamamoto and Takeshi Yasui : Fourier transform spectroscopic optical microscopy using dual-comb spectroscopic technique, 13th Pacific Rim Conference on Lasers and Electro-Optics (CLEO-PR 2018), W4F.3, Hong Kong, Aug. 2018. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85059395964 (Elsevier: Scopus)
78.	Takuya Sakaue, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : Analysis of tissue collagen fibers using rapidly-polarization-modulated second-harmonic-generation microscopy, 13th Pacific Rim Conference on Lasers and Electro-Optics (CLEO-PR 2018), W3A.130, Hong Kong, Aug. 2018.
79.	Takeo Minamikawa, Takashi Masuoka, Takashi Ogura, Kyuki Shibuya, Yoshiaki Nakajima, Yoshihisa Yamaoka, Kaoru Minoshima and Takeshi Yasui : Static and dynamic strain sensing over 3.5 kHz with fiber-based optical frequency comb cavity, 13th Pacific Rim Conference on Lasers and Electro-Optics (CLEO-PR 2018), Tu2L.5, Hong Kong, Jul. 2018. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85065622214 (Elsevier: Scopus)
80.	Ryo Oe, Kosuke Nagai, Takeo Minamikawa, Shuji Taue, Hideki Fukano, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : Refractive index measurement based on disturbance to RF conversion function in a fiber OFC cavity, 13th Pacific Rim Conference on Lasers and Electro-Optics (CLEO-PR 2018), Tu2L.4, Hong Kong, Jul. 2018. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85059365258 (Elsevier: Scopus)
81.	Eiji Hase, Shuji Miyamoto, Takahiko Mizuno, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Dual-comb microscopy for scanless confocal phase imaging, Conference on Lasers and Electro-Optics (CLEO) 2018, STh3L.3, San Jose, May 2018. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85052597587 (Elsevier: Scopus)
82.	Ryo Oe, Kosuke Nagai, Takeo Minamikawa, Shuji Taue, Hideki Fukano, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : Refractive-index-sensing RF comb using intra-cavity multi-mode interference fiber sensor, Conference on Lasers and Electro-Optics (CLEO) 2018, JW2A.146, San Jose, May 2018. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85052551494 (Elsevier: Scopus)
83.	Masatomo Yamagiwa, Takeo Minamikawa, Isao Morohashi, Norihiko Sekine, Iwao Hosako, Hirotsugu Yamamoto and Takeshi Yasui : Real-time multi-wavelength digital holography using line-by-line spectral shaping of optical frequency comb, Conference on Lasers and Electro-Optics (CLEO) 2018, JW2A.155, San Jose, May 2018. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85052606388 (Elsevier: Scopus)
84.	Takeo Minamikawa, Takashi Masuoka, Takashi Ogura, Yoshiaki Nakajima, Yoshihisa Yamaoka, Kaoru Minoshima and Takeshi Yasui : Photo-acoustic sensing with fiber-based optical frequency comb cavity, Conference on Lasers and Electro-Optics (CLEO) 2018, JW2A.141, San Jose, May 2018. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85052570444 (Elsevier: Scopus)
85.	Eiji Hase, Takeo Minamikawa, Katsuya SATO, Daisuke Yonekura, Mitsuhiko Takahashi and Takeshi Yasui : Quantitative evaluation of healing degree in injured tendons based on orientation analysis of collagen fibers by using Fourier-transform second-harmonic-generation microscopy and its relationship to mechanical property, Proceedings of SPIE, Vol.10711, 10711-26, Yokohama, Apr. 2018. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2318673 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85049237183 (DOI: 10.1117/12.2318673, Elsevier: Scopus)
86.	Yuki Ogura, Kohsuke Atsuta, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : In vivo visualization of dermal collagen fibers in human skin using a photonic-crystal-fiber-coupled, hand-held second-harmonic-generation microscope, Proceedings of SPIE, Vol.10711, 10711-43, Yokohama, Apr. 2018. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2316930 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85049254084 (DOI: 10.1117/12.2316930, Elsevier: Scopus)
87.	Takuya Sakaue, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : Analysis of collagen fiber orientation in biological tissues using polarization-resolved second-harmonic-generation microscopy, Proceedings of SPIE, Vol.10711, 10711-44, Yokohama, Apr. 2018. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2319273 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85049246748 (DOI: 10.1117/12.2319273, Elsevier: Scopus)
88.	Eiji Hase, Takeo Minamikawa, Shuji Miyamoto, Yasuhiro Mizutani, Tetsuo Iwata, Hirotsugu Yamamoto and Takeshi Yasui : Application of scan-less two-dimensional confocal microscopy achieved by a combination of confocal slit with wavelength/space conversion, Proceedings of SPIE, Vol.10711, 10711-55, Yokohama, Apr. 2018. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2318671 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85049258723 (DOI: 10.1117/12.2318671, Elsevier: Scopus)
89.	Eiji Hase, Takeo Minamikawa, Shuji Miyamoto, Yasuhiro Mizutani, Tetsuo Iwata, Tetsuo Iwata and Takeshi Yasui : Scan-less, line-filed, confocal phase imaging with dual-comb microscopy, Proceedings of SPIE, Vol.10711, 10711-69, Yokohama, Apr. 2018. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2317029 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85049249855 (DOI: 10.1117/12.2317029, Elsevier: Scopus)
90.	Katsuya SATO, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : Quantitative in situ time-series evaluation of osteoblastic collagen synthesis under cyclic strain using second-harmonic-generation microscopy, Proceedings of SPIE, Vol.10711, 107110Z, Yokohama, Apr. 2018. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2316607 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85049249619 (DOI: 10.1117/12.2316607, Elsevier: Scopus)
91.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Video-rate confocal phase imaging by use of scan-less dual comb microscopy, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10505, 10505-8, San Francisco, Jan. 2018. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2289231 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85047333082 (DOI: 10.1117/12.2289231, Elsevier: Scopus)
92.	Kyuki Shibuya, Takeo Minamikawa, Yasuhiro Mizutani, Hirotsugu Yamamoto, Takeshi Yasui and Tetsuo Iwata : Dual-comb single-pixel imaging in both amplitude and phase, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10505, 10505-31, San Francisco, Jan. 2018. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2288709 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85047370814 (DOI: 10.1117/12.2288709, Elsevier: Scopus)
93.	Ryo Oe, Takeo Minamikawa, Shuji Taue, Hideki Fukano, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : Refractive-index-sensing fiber comb using intracavity multi-mode interference fiber sensor, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.10488, 10488-41, San Francisco, Jan. 2018. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2289252 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85046709889 (DOI: 10.1117/12.2289252, Elsevier: Scopus)
94.	Takeo Minamikawa, Takashi Masuoka, Ryo Oe, Yoshiaki Nakajima, Yoshihisa Yamaoka, Kaoru Minoshima and Takeshi Yasui : Multi-dynamic range compressional wave detection using optical-frequency-comb, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.110464, 110464-105, San Francisco, Jan. 2018. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2288215 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85047300289 (DOI: 10.1117/12.2288215, Elsevier: Scopus)
95.	Takeshi Yasui, Guoqing Hu, Tatsuya Mizuguchi, Xin Zhao, Takeo Minamikawa, Ting Li and Zheng Zheng : Asynchronous-optical-sampling THz time-domain spectroscopy with a free-running, dual-wavelength ,mode-locked fiber laser, 42nd International Conference on Infrared Millimeter and Terahertz Waves, WA4.2, Cancun, Aug. 2017.
96.	Takeshi Yasui, Takayuki Ogawa, Takeo Minamikawa and Hirotsugu Yamamoto : Amplitude and phase imaging of visibly opaque object by THz digital holography, 42nd International Conference on Infrared Millmeter and Terahertz Waves, TD.26, Cancun, Aug. 2017. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85033731429 (Elsevier: Scopus)
97.	Masatomo Yamagiwa, Takayuki Ogawa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Amplitude and phase imaging of optically opaque object using THz digital holography, 24th General Congress of International Commission for Optics, Th1F-03, Tokyo, Aug. 2017.
98.	Takeo Minamikawa and Takeshi Yasui : Absolute frequency measurement using terahertz frequency comb, XXXII International Union of Radio Science General Assembly & Scientific Symposium, A11-3, Montreal, Aug. 2017.
99.	Takuya Sakaue, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : Continuously-polarization-resolved SHG microscopy using electro-optic Pockells cell, 24th General Congress of International Commission for Optics, P5-02, Tokyo, Aug. 2017.
100.	Masatomo Yamagiwa, Takayuki Ogawa, Yusuke Kawahito, Clement Torovato, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Phase imaging by multiple-synthesized-wavelength digital holography using optical frequency synthesizer, 24th General Congress of International Commission for Optics, P3-45, Tokyo, Aug. 2017.
101.	Takashi Masuoka, Takashi Ogura, Takeo Minamikawa, Yoshiaki Nakajima, Yoshihisa Yamaoka, Kaoru Minoshima and Takeshi Yasui : Detection of ultrasonic wave using optical-frequency-comb cavity, 24th General Congress of International Commission for Optics, P3-114, Tokyo, Aug. 2017.
102.	Kyuki Shibuya, Takeo Minamikawa, Yasuhiro Mizutani, Takeshi Yasui and Tetsuo Iwata : Mode-resolved amplitude and phase imaging by dual-comb spectroscopy combined with a single-pixel imaging, 24th General Congress of International Commission for Optics, P3-03, Tokyo, Aug. 2017.
103.	Masatomo Yamagiwa, Takayuki Ogawa, Yusuke Kawahito, Clement Torovato, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Shape measurement by cascade link multi-wavelength digital holography using optical frequency comb referenced synthesizer, 2017 CLEO Pacific Rim Conference, Oral3-3F-5, Singapore, Aug. 2017.
104.	Takashi Masuoka, Takashi Ogura, Takeo Minamikawa, Yoshiaki Nakajima, Yoshihisa Yamaoka, Kaoru Minoshima and Takeshi Yasui : Developement of ultrasonic sensor using fiber-based optical-frequency-comb cavity, 2017 CLEO Pacific Rim Conference, P3-114, Singapore, Aug. 2017.
105.	Takeo Minamikawa : (Invited) Raman spectroscopic detection of peripheral nerves towards nerve-sparing surgery, CLEO-PR, OECC and PGC 2017, Singapore, Aug. 2017.
106.	Masatomo Yamagiwa, Takayuki Ogawa, Yusuke Kawahito, Clement Torovato, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Multiple-synthesized-wavelengths digital holography using optical frequency synthesizer, Digital Holography & 3-D Imaging 2017, Tu1A.5, Jeju Island, May 2017. (Link to Publication Site) ● Publication site (DOI): 10.1364/DH.2017.Tu1A.5 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85026304172 (DOI: 10.1364/DH.2017.Tu1A.5, Elsevier: Scopus)
107.	Masatomo Yamagiwa, Takayuki Ogawa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Off-axis digital holography in THz region, Digital Holography & 3-D Imaging 2017, TM3A.5, Jeju Island, May 2017. (Link to Publication Site) ● Publication site (DOI): 10.1364/DH.2017.M3A.5 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85026325654 (DOI: 10.1364/DH.2017.M3A.5, Elsevier: Scopus)
108.	Takeo Minamikawa, Eiji Hase, Shuji Miyamoto, Hirotsugu Yamamoto and Takeshi Yasui : Development of confocal laser scanning microscopy by use of optical frequency comb, Conference on Lasers and Electro-Optics (CLEO) 2017, SF2C.3, San Jose, May 2017. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85044178075 (Elsevier: Scopus)
109.	Masatomo Yamagiwa, Takayuki Ogawa, Yusuke Kawahito, Takeo Minamikawa, Hirotsugu Yamamoto, Takeshi Yasui and Clement Torovato : Digital holography using multiple synthesized wavelengths cascaded by optical frequency synthesizer, Conference on Lasers and Electro-Optics (CLEO) 2017, JTh2A.71, San Jose, May 2017. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEO_QELS.2017.JTh2A.71 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85044233355 (DOI: 10.1364/CLEO_QELS.2017.JTh2A.71, Elsevier: Scopus)
110.	Kyuki Shibuya, Takeo Minamikawa, Yasuhiro Mizutani, Takeshi Yasui and Tetsuo Iwata : Dual-comb single-pixel imaging for scan-less hyperspectral imaging, Conference on Lasers and Electro-Optics (CLEO) 2017, STh3L.5, San Jose, May 2017. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEO_SI.2017.STh3L.5 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85044176680 (DOI: 10.1364/CLEO_SI.2017.STh3L.5, Elsevier: Scopus)
111.	Guoqing Hu, Tatsuya Mizuguchi, Xin Zhao, Takeo Minamikawa, Ting Li, Zheng Zheng and Takeshi Yasui : Terahertz dual-comb spectroscopy with a free-running, dual-wavelength-comb fiber laser, Conference on Lasers and Electro-Optics (CLEO) 2017, SW4J.1, San Jose, May 2017. (Link to Publication Site) ● Publication site (DOI): 10.1364/CLEO_SI.2017.SW4J.1 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85044412501 (DOI: 10.1364/CLEO_SI.2017.SW4J.1, Elsevier: Scopus)
112.	Takeo Minamikawa, Eiji Hase, Shuji Miyamoto, Yi-Da Hsieh, Hirotsugu Yamamoto and Takeshi Yasui : Fourier transform-based confocal microscopy using image-encoded optical-frequency-comb, Focus on Microscopy 2017, P2-F/20, Bordeaux, Apr. 2017.
113.	Takeshi Yasui, Eiji Hase, Takeo Minamikawa and Katsuya SATO : In situ second-harmonic-generation imaging of collagen fibers produced by standing-cultured osteoblasts, Focus on Microscopy 2017, P1-E/7, Bordeaux, Apr. 2017.
114.	Guoqing Hu, Tatsuya Mizuguchi, Xin Zhao, Takeo Minamikawa, Takahiko Mizuno, Yuli Yang, Cui Li, Ming Bai, Zheng Zheng and Takeshi Yasui : Real-time frequency measurement of CW-THz radiation using dual photo-carrier THz combs induced by a free-running, dual-wavelength mode-locked, Er:fiber laser, 7th International Conference on Optical Terahertz Science and Technology, PS3:04, London, Apr. 2017.
115.	Yi-Da Hsieh, Shota Nakamura, Takeo Minamikawa, Hindle Francis and Takeshi Yasui : Real-time monitoring of gas concentration mixed with unwanted smoke under "atmospheric pressure using asynchronous-optical-sampling THz time-domain spectroscopy, 7th International Conference on Optical Terahertz Science and Technology, PS2:01, London, Apr. 2017.
116.	Eiji Hase, Takeo Minamikawa, Katsuya SATO, Daisuke Yonekura, Mitsuhiko Takahashi and Takeshi Yasui : Orientation analysis of collagen fibers in healing tendon by using second-harmonic-generation microscopy, SPIE Photonics West, Biomedical Optics (BiOS 2017), 10069-8, San Francisco, Feb. 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2251111 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85020294503 (DOI: 10.1117/12.2251111, Elsevier: Scopus)
117.	Kyuki Shibuya, Takeo Minamikawa, Yasuhiro Mizutani, Takeshi Yasui and Tetsuo Iwata : Hyperspectral single-pixel imaging with dual optical comb, SPIE Photonics West, Biomedical Optics (BiOS 2017), 10076-47, San Francisco, Feb. 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2251250 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85020300077 (DOI: 10.1117/12.2251250, Elsevier: Scopus)
118.	Takeo Minamikawa, Harada Yoshinori and Takamatsu Tetsuro : Raman spectroscopic detection of peripheral nerves towards nerve-sparing surgery, SPIE Photonics West, Biomedical Optics (BiOS 2017), Vol.10054, San Francisco, CA, USA, Feb. 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2250807 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85018930329 (DOI: 10.1117/12.2250807, Elsevier: Scopus)
119.	Takeo Minamikawa, Matsuo Hisataka, Kato Yoshiyuki, Harada Yoshinori, Otsuji Eigo, Yanagisawa Akio, Tanaka Hideo and Takamatsu Tetsuro : Simple and optimum background-free estimation method of PPIX fluorescence for 5-ALA-based fluorescence diagnosis of malignant lesions, SPIE Photonics West, Biomedical Optics (BiOS 2017), Vol.10047, San Francisco, Feb. 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2250780 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85019262322 (DOI: 10.1117/12.2250780, Elsevier: Scopus)
120.	Takeo Minamikawa, Takashi Ogura, Takashi Masuoka, Eiji Hase, Yoshiaki Nakajima, Yoshihisa Yamaoka, Kaoru Minoshima and Takeshi Yasui : Optical-frequency-comb-based ultrasound sensor, SPIE Photonics West, Biomedical Optics (BiOS 2017), 10064-192, San Francisco, Jan. 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2250792 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85018866599 (DOI: 10.1117/12.2250792, Elsevier: Scopus)
121.	Kosuke Atsuta, Yuki Ogura, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : In situ monitoring of collagen fibers in human skin using a photonic-crystal-fiber-coupled, hand-held, second-harmonic-generation microscope, SPIE Photonics West, Biomedical Optics (BiOS 2017), 10069-81, San Francisco, Jan. 2017. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2251321 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85020313109 (DOI: 10.1117/12.2251321, Elsevier: Scopus)
122.	Shuji Miyamoto, Eiji Hase, Takeo Minamikawa, Takeshi Yasui and Hirotsugu Yamamoto : Video-rate volume imaging confocal microscope based on wavelength / space conversion by use of multichannel spectrometer, Frontier in Optics (FiO) 2016, JTh2A.128, New York, Oct. 2016. (Link to Publication Site) ● Publication site (DOI): 10.1364/FIO.2016.JTh2A.128 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1364/FIO.2016.JTh2A.128 (DOI: 10.1364/FIO.2016.JTh2A.128)
123.	Tatsuya Mizuguchi, Guoqing Hu, Xin Zhao, Takeo Minamikawa, Yuli Yang, Cui Li, Zheng Zheng and Takeshi Yasui : Real-time Absolute Frequency Measurement Of CW-THz Radiation Using Dual THz Combs Induced By A Free-running, Dual-wavelength, Mode-locked Fiber Laser, 41st International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz2016), W5P.15.02, Copenhagen, Sep. 2016. (Link to Publication Site) ● Publication site (DOI): 10.1109/IRMMW-THz.2016.7759012 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85006153529 (DOI: 10.1109/IRMMW-THz.2016.7759012, Elsevier: Scopus)
124.	Takayuki Ogawa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Off-Axis THz digital holography by use of THz quantum cascade laser and uncooled micro-bolometer array detector, 41st International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz2016), T5P.09.07, Copenhagen, Sep. 2016. (Link to Publication Site) ● Publication site (DOI): 10.1109/IRMMW-THz.2016.7758807 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85006124358 (DOI: 10.1109/IRMMW-THz.2016.7758807, Elsevier: Scopus)
125.	Takeo Minamikawa, Yi-Da Hsieh, Kyuki Shibuya, Yoshiki Kaneoka, Sho Okubo, Hajime Inaba, Yasuhiro Mizutani, Takeshi Yasui and Tetsuo Iwata : Dual-optical-comb spectroscopic ellipsometry, Conference on Lasers and Electro-Optics (CLEO) 2016, SW1H.5, San Jose, Jun. 2016. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85010702323 (Elsevier: Scopus)
126.	Eiji Hase, Shuji Miyamoto, Yi-Da Hsieh, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : Scan-less, line-field, confocal microscopy based on dimensional-conversion optical frequency comb, Conference on Lasers and Electro-Optics (CLEO) 2016, SW1H.3, San Jose, Jun. 2016. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85010645273 (Elsevier: Scopus)
127.	Takeshi Yasui, Takashi Ogura, Takeo Minamikawa, Yoshiaki Nakajima and Kaoru Minoshima : Strain sensing with a disturbance/RF-converting fiber comb cavity, Conference on Lasers and Electro-Optics (CLEO) 2016, AM2J.1, San Jose, Jun. 2016. (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85010651082 (Elsevier: Scopus)
128.	Guoqing Hu, Tatsuya Mizuguchi, Xin Zhao, Takeo Minamikawa, Yuli Yang, Cui Li, Zheng Zheng and Takeshi Yasui : Real-time absolute frequency measurement of continuous-wave terahertz radiation using a free-running, dual-wavelength, dual-comb mode-locked fiber laser, Conference on Lasers and Electro-Optics (CLEO) 2016, SM1H.2, San Jose, Jun. 2016. (Link to Publication Site) ● Publication site (DOI): 10.1364/cleo_si.2016.sm1h.2 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-85010682297 (DOI: 10.1364/cleo_si.2016.sm1h.2, Elsevier: Scopus)
129.	Shuji Miyamoto, Eiji Hase, Ryuji Ichikawa, Takeo Minamikawa, Takeshi Yasui and Hirotsugu Yamamoto : One shot confocal microscopy based on wavelength / space conversion by use of multichannel spectrometer, Proceedings of SPIE, Vol.9720, 97201C, San Francisco, Feb. 2016. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2213814 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84982090933 (DOI: 10.1117/12.2213814, Elsevier: Scopus)
130.	Eiji Hase, Takeo Minamikawa, Katsuya SATO, Mitsuhiko Takahashi and Takeshi Yasui : Observation of tendon repair in animal model using second-harmonic-generation microscopy, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.9712, 97121R, San Francisco, Feb. 2016. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2213890 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84975062041 (DOI: 10.1117/12.2213890, Elsevier: Scopus)
131.	Takeshi Yasui, Eiji Hase, Shuji Miyamoto, Yi-Da Hsieh, Takeo Minamikawa and Hirotsugu Yamamoto : Scan-less, line-field confocal microscopy by combination of wavelength/space conversion with dual optical comb, Proceedings of SPIE, Vol.9720, 972006, San Francisco, Feb. 2016. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2213560 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84982133275 (DOI: 10.1117/12.2213560, Elsevier: Scopus)
132.	Takeo Minamikawa, Tsunehisa Yamamoto, Nanae Nishiki-Muranishi, Yoshinori Harada and Tetsuro Takamatsu : Label-free evaluation of myocardial infarction by spontaneous Raman spectroscopy, SPIE Photonics West, Biomedical Optics (BiOS 2015), San Francisco, Feb. 2015.
133.	Takeo Minamikawa, Yoshinori Harada and Tetsuro Takamatsu : In vivo and ex vivo detection of peripheral nerves of rats by using Raman spectroscopy, Focus on Microscopy 2014, Sydney, Apr. 2014.
134.	Takeo Minamikawa, Nanae Muranishi, Yoshinori Harada and Tetsuro Takamatsu : Raman spectroscopic estimation of myocardial infarction, SPIE BiOS 2014, Feb. 2014.
135.	Takeo Minamikawa, Noriaki Koizumi, Yoshinori Harada, Eigo Otsuji and Tetsuro Takamatsu : Photooxidization-assisted-photodynamic diagnosis of lymph node metastasis using 5-aminolevulinic acid, SPIE BiOS 2014, Feb. 2014.
136.	Takeo Minamikawa, Yoshinori Harada, Noriaki Koizumi and Tetsuro Takamatsu : Raman microspectroscopy for peripheral nerve detection, 7th International Conference on Advanced Vibrational Spectroscopy (ICAVS-7), Aug. 2013.
137.	Takeo Minamikawa, Yoshinori Harada, Noriaki Koizumi and Tetsuro Takamatsu : Multivariate analysis of Raman spectra for peripheral nerve detection in human periprostatic tissues, Focus on Microscopy 2013, Maastricht, The Netherland, Mar. 2013.
138.	Takeo Minamikawa, Yoshinori Harada, Noriaki Koizumi and Tetsuro Takamatsu : Raman microspectroscopy for visualization of peripheral nerves, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.8588, 85880P, Feb. 2013. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.2001015 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84878680343 (DOI: 10.1117/12.2001015, Elsevier: Scopus)
139.	Tsunehisa Yamamoto, Yoshinori Harada, Takeo Minamikawa, Sadahisa Yamaoka, Hitoshi Yaku and Tetsuro Takamatsu : Abstract 14238: Label-free Imaging of Human Heart by Raman Microspectroscopy, Circulation, Vol.128, No.Suppl 22, A14238, 2013. (Summary) Introduction: The accurate elucidation of myocardial viability is a critical issue in determining the resection region of cardiac tissue in surgical ventricular restoration (SVR). In general, the myocardial viability is evaluated before the operation by using MRI and myocardial scintigraphy. These methods are difficult to apply for real time evaluation of the myocardial viability during the SVR operation. Raman spectroscopy is an ideal and valuable analytical tool in biological and medical fields, allowing identification of states of tissue via detecting molecular vibrations of intrinsic molecules in the tissue without labels or extensive preparations. In this study, we evaluated a new method of human cardiac tissue to identify cardiomyocytes from fibrotic tissue by Raman microspectroscopy for the first time.Method: Cardiac tissues were resected from five ischemic cardiomyopathy patients who underwent SVR. The resection stumps were immediately snap-frozen in liquid nitrogen and were sliced into 5-um-thick serial sections with a cryostat microtome. Raman spectra and 2D Raman images were acquired with a laser Raman confocal microscope (laser wavelength: 532 nm). Serial sections for staining were used to confirm histology. First, we analyzed the spectra of the regions of cardiomyocytes and fibrotic tissue. Second, we compared the acquired Raman images with the serial pathological images. This study was conducted after obtaining approval from the Ethics Committee of Kyoto Prefectural University of Medicine.Result: In the region of cardiomyocytes, Raman peaks were mainly assigned to cytochrome. On the other hand, in the region of fibrotic tissue, Raman peaks were mainly assigned to collagen type I. The 2D Raman images almost coincided with the serial pathological images, in which the peaks at 751, 1130 and 1582 cm-1 corresponded to the cardiomyocytes, and the peak at 2943 cm-1 to the collagen type I.Conclusion: By applying the Raman spectroscopy to the human heart, we visualized intact and infarcted myocardial regions at the cellular level without labeling for the first time. Raman microspectroscopy is a useful tool for the detection of myocardial viability. This feasible method is applicable to intraoperative non-invasive cardiac imaging.
140.	Takeo Minamikawa, Yoshinori Harada, Noriaki Koizumi and Tetsuro Takamatsu : Label-free identification of Peripheral Nerves by Raman microscopy, The 14th International Congress of Histochemistry and Cytochemistry, Kyoto, Aug. 2012.
141.	Takeo Minamikawa, Yoshinori Harada, Noriaki Koizumi and Tetsuro Takamatsu : Label-free spontaneous Raman observation for nerve tissue discrimination, Focus on Microscopy 2012, Singapore, Apr. 2012.
142.	Takeo Minamikawa, Yoshinori Murakami, Naokazu Matsumura, Hirohiko Niioka, Shuichiro Fukushima, Tsutomu Araki and Mamoru Hashimoto : Photo-induced cell damage analysis for multi-focus CARS microscopy, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.7903, 79032H, San Francisco, Jan. 2011. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.874677 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.1117/12.874677 (DOI: 10.1117/12.874677)
143.	Takeo Minamikawa, Hirohiko Niioka, Tsutomu Araki and Mamoru Hashimoto : Three-dimensional CARS imaging of membrane disruption and repair using multi-focus CARS microscope, Focus on Microscopy 2010, Shanghai, Mar. 2010.
144.	Takeo Minamikawa, Tsutomu Araki and Mamoru Hashimoto : Real-time molecular imaging of organelles in living cell by multi-focus excitation CARS microscope, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.7569, 756927, San Francisco, Feb. 2010. (Summary) We demonstrated real-time imaging of organelles in a living HeLa cell with a multi-focus excitation CARS (coherent anti-Stokes Raman scattering) microscope. By the multi-focus excitation, image exposure time is prolonged proportionally to number of the foci, and thus a high signal-to-noise ratio imaging will achieved comparing with a single beam scanning method. Two ps Ti:sapphire lasers were used as light source. Laser pulse duration was automatically minimized and the two lasers were synchronized within 30 fs with the bandwidth of 150 Hz. The multiple foci were formed with a microlens array disk scanner. We observed a living HeLa cells at 2840 cm-1 which originates in CH2 stretching vibration. The image acquisition rate of 10 frames per second was achieved. We also obtained z-sectioned images of living HeLa cells with 80 sections over 8 micrometers, and three-dimensional distribution of lipid rich organelles, such as mitochondria, lipid rich vesicles, and nucleolus, was visualized within 16 s. (Link to Publication Site) ● Publication site (DOI): 10.1117/12.842346 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-77951704916 (DOI: 10.1117/12.842346, Elsevier: Scopus)
145.	Takeo Minamikawa, Tsutomu Araki and Mamoru Hashimoto : Multiplex multi-focus coherent anti-Stokes Raman scattering microscopy, Focus on Microscopy 2009, 254, Krakow, Poland, Apr. 2009.
146.	Takeo Minamikawa, Tsutomu Araki and Mamoru Hashimoto : Lipids distribution imaging of lipid vesicles by multi-focus excitation CARS microscope, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol.7183, 718328, San Jose, Feb. 2009. (Summary) We demonstrated high-speed imaging of the distribution of DPPC (dipalmitoylphosphatidylcholine), d62-DPPC (deuterated DPPC), and DOPC (dioleoylphosphatidylcholine) lipids in a lipid vesicle with a multi-focus excitation CARS (coherent anti-Stokes Raman scattering) microscope using a microlens array scanner. By the multi-focus excitation, the dwell time is increased in proportion to the number of focal spots compared with a single beam scanning, and high-speed and high-quality CARS imaging is possible without increasing the peak power of each spot. We demonstrated the selectively visualization of DPPC and d62-DPPC lipid vesicles, in which the vesicles contain a type of lipid, by observing at 2840 cm-1 and 2090 cm-1. We also visualized the DOPC and DPPC lipids distribution in a lipid mixture vesicle observed at 1440 cm-1 and 1655 cm-1. The image acquisition time of 10 s/image at each Raman shift was realized. The signal ratio of 1440 cm-1 and 1655 cm-1 was locally intense on the lipid vesicle. It must be because the gel phase domain of DPPC lipids was exists in the DOPC lipids which were liquid-crystalline phase at room temperature. (Keyword) CARS microscopy Multi-focus excitation Real-time imaging Lipid vesicle Lipid distribution (Link to Publication Site) ● Publication site (DOI): 10.1117/12.808679 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-65949097250 (DOI: 10.1117/12.808679, Elsevier: Scopus)
147.	Takeo Minamikawa, Tsutomu Araki and Mamoru Hashimoto : Real-time, label-free, and high resolution biomolecular imaging of living cells using multi-focus coherent anti-Stokes Raman scattering microscope, 3rd East Asian Pacific Student Workshop on Nano-Biomedical Engineering, Singapore, 2009.
148.	Takeo Minamikawa, Tsutomu Araki and Mamoru Hashimoto : High-speed, three-dimensional direct imaging of lipid vesicles with multi-focus excitaion CARS microscope, The 3rd MEI International Symposium, 74, San Francisco, Nov. 2008.
149.	Takeo Minamikawa, Naoki Tanimoto, Mamoru Hashimoto, Tsutomu Araki, Katsumasa Fujita and Satoshi Kawata : Realtime imaging of lipid bilayer vesicle with multi-focus CARS microscope, Focus on Microscopy 2008, 74, Hyogo Prefecture, Apr. 2008.
150.	Takeo Minamikawa, Naoki Tanimoto, Mamoru Hashimoto, Minoru Kobayashi, Katsumasa Fujita, Satoshi Kawata and Tsutomu Araki : Coherent anti-Stokes Raman Scattering (CARS) microscopy system for high quality spectral-Imaging, The 9th International Conference on Optics Within Life Sciences, Taipei, Nov. 2006.
151.	Takeo Minamikawa, Naoki Tanimoto, Mamoru Hashimoto, Minoru Kobayashi, Katsumasa Fujita, Satoshi Kawata and Tsutomu Araki : Jitter reduction of light source for CARS microscopy, The 20th International Conference on Raman Spectroscopy, 174, Yokohama, Aug. 2006.

Proceeding of Domestic Conference:

1.	TOKIYA Ohe, Takeo Minamikawa and Katsuya SATO : Effects of micro-vibration stimuli on the osteoblasts synthesized substrate -Evaluation of Calcification using Raman spectroscopy-, 第34回バイオフロンティア講演会, 2F01, Dec. 2023.
2.	SOTA Inoue, Hiroki Tanioka, Takeshi Yasui, 川崎昌博, 川崎三津夫 and Takeo Minamikawa : 金属との近接を必要としないリモートプラズモニックラマン増強基板の化学的安定性評価, 第84回応用物理学会秋季学術講演会, 23a-A309-6, Sep. 2023.
3.	Masayuki Higaki, MIYAMURA Shogo, 田上周路, Yu Tokizane, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : THz コム周波数逓倍による屈折率センシング光コムの高感度化, 第84回応用物理学会秋季学術講演会, 22p-A602-4, Sep. 2023.
4.	HIROKI Kitahama, Hidenori Koresawa, Eiji Hase, 浅原彰文, Takeo Minamikawa and Takeshi Yasui : デュアル光コム分光偏光計による偏光素子の計測, 第84回応用物理学会秋季学術講演会, 21a-A602-4, Sep. 2023.
5.	湯本拓実, 内山竜成, 穀山渉, Yu Tokizane, Takeo Minamikawa, Takeshi Yasui, 松原伸一 and Yoshiaki Nakajima : 100-MHz 全偏波保持機構共有型デュアルコムファイバレーザーの開発, 第84回応用物理学会秋季学術講演会, 20p-B204-7, Sep. 2023.
6.	Naoya Ohkubo, Eiji Hase, KAZUKI Yasumaru, Yu Tokizane, Takeo Minamikawa and Takeshi Yasui : ブリルアン・ラマン散乱顕微鏡を用いた非アルコール性脂肪性疾患における脂質の分子物性解析(2) ~蓄積脂肪滴のブリルアンイメージング~, 第84回応用物理学会秋季学術講演会, 20p-A305-14, Sep. 2023.
7.	Tomohiro Tamaki, Takeo Minamikawa, Eiji Hase, Mayuko Shimizu, Yuki Morimoto, Akihiro Suzuki, Takeshi Yasui, 中村聡子, Akemi Tsutsui, 高口浩一 and Koichi Tsuneyama : ヒト非アルコール性脂肪性肝疾患における超早期肝線維化のSHG偏光顕微鏡解析, 第84回応用物理学会秋季学術講演会, 20p-A305-13, Sep. 2023.
8.	Katsuya SATO, Takeo Minamikawa and Takeshi Yasui : Compositional evaluation of osteoblasts synthesized matrix under micro-vibration stimuli by Raman spectroscopy, 生体医工学シンポジウム2023, Sep. 2023.
9.	Takeo Minamikawa : 深紫外光を用いた新型コロナウイルス不活化, 光源・光学素子EXPO 2023, Apr. 2023.
10.	Mayuko Shimizu, Takeo Minamikawa, Eiji Hase, 筒井朱美, Hirohisa Ogawa and Koichi Tsuneyama : A New Approach to Evaluate NASH Pathophysiology Using Liver Tissue, 第112回日本病理学会総会, Apr. 2023. (Keyword) NASH / liver biopsy / SHG / Raman
11.	SOTA Inoue, Takeo Minamikawa, Hiroki Tanioka, Takeshi Yasui, 森本幸裕, 川崎昌博 and 川崎三津夫 : 金属との近接を必要としないリモートプラズモニックラマン増強基板の化学的処理による光増強特性の変化, 第70回応用物理学会春季学術講演会, 17a-A305-8, Mar. 2023.
12.	YUYA Kodama, Hidenori Koresawa, Eiji Hase, Yu Tokizane, Takeo Minamikawa, Tsutomu Araki and Takeshi Yasui : 波長/角度変換光コムを用いた角度SPRスペクトルのデュアル光コム分光, 第70回応用物理学会春季学術講演会, 17p-A502-10, Mar. 2023.
13.	HIROKI Kitahama, Hidenori Koresawa, Eiji Hase, 浅原彰文, Takeo Minamikawa and Takeshi Yasui : デュアル光コム分光偏光計の安定化に関する検討, 第70回応用物理学会春季学術講演会, 17a-A502-3, Mar. 2023.
14.	Kazuki Sadahiro, Yu Tokizane, Eiji Hase, Takeo Minamikawa, 諸橋功 and Takeshi Yasui : モード抽出光周波数コムを用いたフルカスケードリンク型マルチ合成波⻑デジタル·ホログラフィーによる表面形状測定法, 第70回応用物理学会春季学術講演会, 16p-A303-3, Mar. 2023.
15.	KAZUKI Yasumaru, Takeo Minamikawa, Eiji Hase, 清水真裕子, Takeshi Yasui and Koichi Tsuneyama : 非アルコール性脂肪性肝疾患モデルマウスの肝臓に蓄積した脂肪滴の相転移, 第70回応用物理学会春季学術講演会, 15p-A405-6, Mar. 2023.
16.	Takeo Minamikawa : リモートプラズモニック光増強分光法∼金属との近接が不要なプラズモン-分子相互作用の可能性∼, 日本光学会ナノオプティクス研究グループ第29回研究討論会, Jan. 2023.
17.	Takeo Minamikawa : 医学の新たな地平を拓くフォトニクス, Retreat in Kochi, Jan. 2023.
18.	SOTA Inoue, Takeo Minamikawa, Takeshi Yasui, 森本幸裕, 川崎昌博 and 川崎三津夫 : 金属との接触を必要としないプラズモン-分子リモートカップリングによる光増強ラマン分光法の基礎増強特性評価, レーザー学会学術講演会第43回年次大会, P01-20p-P-22, Jan. 2023.
19.	Takeo Minamikawa : ラマン散乱分光法の病理学への応用, レーザー学会第43回年次大会, Jan. 2023.
20.	Shogo Miyamura, Ryo Oe, Takuya Nakahara, Shota Okada, 田上周路, Yu Tokizane, Takeo Minamikawa, Taka-aki Yano, Kunihiro Otsuka, Ayuko Sakane, Takuya Sasaki, Koji Yasutomo, Taira Kajisa and Takeshi Yasui : デュアル光コムバイオセンシングによるSARS-CoV-2/NP抗原の迅速·高感度検出, 学術講演会第43回年次大会, E06-19p-IX-01, Jan. 2023.
21.	Takeo Minamikawa : 深紫外LEDのウイルス不活化応用, 日本学術振興会第R032委員会第10回研究会, Jan. 2023.
22.	Takeo Minamikawa : 深紫外光を用いた新型コロナウイルスの不活化, 光産業技術マンスリーセミナー, Dec. 2022.
23.	Hayata Tadamasa, Takeo Minamikawa, 鈴木昭弘 and Takeshi Yasui : ラマン分光法による細胞内脂肪滴中の脂質分子解析, 第33回バイオフロンティア講演会, 1E06, Dec. 2022.
24.	Kazuki Furuya, Eiji Hase, Takeo Minamikawa, Takeshi Yasui and Katsuya SATO : Changes in collagen production of osteoblasts subjected to microvibration stimulation including resting phase, 日本機械学会第33回バイオフロンティア講演会講演論文, 2E04, Dec. 2022.
25.	Takeo Minamikawa : ラマン散乱分光法の医学への展開∼医学に新しい価値観を創造する∼, 第55回光学四学会関西支部連合講演会, Dec. 2022.
26.	YUYA Kodama, Hidenori Koresawa, Eiji Hase, Yu Tokizane, Takeo Minamikawa and Takeshi Yasui : 角度変換光コムSPRを用いた屈折率センシング, 第7回フォトニクスワークショップ, 1-P-3, Nov. 2022.
27.	HIROKI Kitahama, Hidenori Koresawa, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : デュアル光コム偏光分光測定法の基本特性評価, 第7回フォトニクスワークショップ, 1-P-25, Nov. 2022.
28.	貞廣知輝, Yu Tokizane, Eiji Hase, Takeo Minamikawa, 諸橋功 and Takeshi Yasui : モード抽出電気光学変調器光コムを用いた波長走査・単一波長接続型デジタルホログラフィ, 第7回フォトニクスワークショップ, 1-P-23, Nov. 2022.
29.	TOMOYA Okabe, Takeo Minamikawa, Keishiroh Ohtani, KAJIWARA Shimpei, Eiji Hase and Takeshi Yasui : 透過型ステージ走査型光コム顕微鏡の開発, 第7回フォトニクスワークショップ, 1-P-21, Nov. 2022.
30.	TOMOHIRO Tamaki, Takeo Minamikawa, Eiji Hase, Mayuko Shimizu, 森本友樹, 鈴木昭浩, Takeshi Yasui, 中村聡子, 筒井朱美, 高口浩一 and Koichi Tsuneyama : SHG 顕微鏡によるヒト非アルコール性脂肪性肝疾患の超早期肝線維化の評価, 第7回フォトニクスワークショップ, 1-P-12, Nov. 2022.
31.	Hayata Tadamasa, Takeo Minamikawa, 鈴木昭弘 and Takeshi Yasui : ラマン分光法を用いた細胞における脂質の取り込み評価, 第7回フォトニクスワークショップ, 1-P-10, Nov. 2022.
32.	KAZUKI Yasumaru, Takeo Minamikawa, Eiji Hase, Mayuko Shimizu, Takeshi Yasui and Koichi Tsuneyama : 非アルコール性脂肪性肝疾患の肝臓中に蓄積した脂肪滴の分光学的観察, 第7回フォトニクスワークショップ, 1-P-8, Nov. 2022.
33.	Koshiro Hori, Takeo Minamikawa, Yoshiki Terao, Masami Shishibori and Takeshi Yasui : 線形SVMとラマン分光法よる判別根拠が明確な神経判別手法の開発, 第7回フォトニクスワークショップ, 1-P-6, Nov. 2022.
34.	SOTA Inoue, Takeo Minamikawa, Hiroki Tanioka, Takeshi Yasui, 森本幸裕, 川崎昌博 and 川崎三津夫 : リモートプラズモニック光増強ラマン分光法の基礎増強特性評価, 第7回フォトニクスワークショップ, 1-P-27, Nov. 2022.
35.	Takeo Minamikawa, SOTA Inoue, Hiroki Tanioka, Takeshi Yasui, 森本幸裕, 川崎昌博 and 川崎三津夫 : 100 nm を超えるプラズモン-分子長距離カップリングを用いたリモートプラズモニック光増強ラマン分光法, レーザー顕微鏡研究会第47回講演会, Nov. 2022.
36.	Takeo Minamikawa : ラマン散乱分光法の病理学への展開 ∼病理学に新しい価値観を創造する∼, 第5回超高速光エレクトロニクス研究会, Nov. 2022.
37.	HIROKI Kitahama, Akira Emoto, 鈴木昭浩, Atsuo Ochi, Takeo Minamikawa, 中村怜 and Takeshi Yasui : 定量的殺菌効果の評価指標を用いた各種紫外光源の比較実験, Optics and Photonics Japan 2022, 16pD7, Nov. 2022.
38.	TOMOYA Okabe, Takeo Minamikawa, Keishiroh Ohtani, KAJIWARA Shimpei, Eiji Hase and Takeshi Yasui : 透過型光コム顕微鏡の開発と異方性物質の偏光分光イメージング, Optics and Photonics Japan 2022, P24, Nov. 2022.
39.	Hayata Tadamasa, Takeo Minamikawa, Yoshiki Terao, Koshiro Hori and Takeshi Yasui : 主成分分析と判別結果の網羅的因果律推定による生体組織判別のためのラマンスペクトルの潜在的特徴の抽出, Optics and Photonics Japan 2022, 14aE6, Nov. 2022.
40.	Hidenori Koresawa, Takeo Minamikawa, Yutaro Onishi, Hayata Tadamasa, Mayuko Shimizu, 森本友樹, Eiji Hase, Takeshi Yasui and Koichi Tsuneyama : ラマン顕微鏡による非アルコール性脂肪性肝疾患における脂肪滴の解析, Optics and Photonics Japan 2022, 16pD6, Nov. 2022.
41.	KAJIWARA Shimpei, Takeo Minamikawa, TOMOYA Okabe, Eiji Hase and Takeshi Yasui : 透過型レーザー走査型光周波数コム顕微鏡によるマルチパラメータ評価, Optics and Photonics Japan 2022, 16Ea11, Nov. 2022.
42.	KAZUKI Yasumaru, Takeo Minamikawa, Eiji Hase, Mayuko Shimizu, Takeshi Yasui and Koichi Tsuneyama : 非アルコール性脂肪性肝疾患モデルマウスの肝臓に蓄積した脂肪滴のラマン・SHGイメージング, Optics and Photonics Japan 2022, 16pD5, Nov. 2022.
43.	HIROKI Kitahama, Hidenori Koresawa, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 偏光制御パルス列のデュアル光コム分光を用いたジョーンズ行列測定, Optics and Photonics Japan 2022, 15aE9, Nov. 2022.
44.	Kazuki Sadahiro, Yu Tokizane, Eiji Hase, Takeo Minamikawa, 諸橋功 and Takeshi Yasui : モード抽出光コムによる波長走査型・単一波長型デジタルホログラフィーの接続, Optics and Photonics Japan 2022, 14aD3, Nov. 2022.
45.	TOMOHIRO Tamaki, Takeo Minamikawa, Eiji Hase, Mayuko Shimizu, 森本友樹, 鈴木昭浩, Takeshi Yasui, 中村聡子, 筒井朱美, 高口浩一 and Koichi Tsuneyama : SHG顕微鏡によるヒト非アルコール性脂肪性肝疾患の超早期肝線維化の評価, Optics and Photonics Japan 2022, 16pD4, Nov. 2022.
46.	SOTA Inoue, Takeo Minamikawa, Hiroki Tanioka, Takeshi Yasui, 森本幸裕, 川崎昌博 and 川崎三津夫 : 数十nmのシリカ柱上構造を介したプラズモン-分子リモートカップリングによる光増強ラマン分光法, Optics and Photonics Japan 2022, P4, Nov. 2022.
47.	Hidenori Koresawa, Kohta Seki, Eiji Hase, Yu Tokizane, Taira Kajisa, Takeo Minamikawa and Takeshi Yasui : 高速入射角走査型近赤外表面プラズモン共鳴センサーの高度化, 第83回応用物理学会秋季学術講演会, 23p-C302-10, Sep. 2022.
48.	Takeo Minamikawa, 原田義規, 高松哲郎, 森本幸裕, 川崎昌博 and 川崎三津夫 : シリカ柱上構造を介したリモートプラズモニック光増強効果を援用した生体組織の高感度ラマンイメージング, 第83回応用物理学会秋季学術講演会, Sep. 2022.
49.	Takeo Minamikawa, 森本幸裕, 川崎昌博 and 川崎三津夫 : シリカ柱状構造を介したプラズモン-分子リモートカップリングによるリモートプラズモニック光増強ラマン分光法, 第83回応用物理学会秋季学術講演会, Sep. 2022.
50.	YUYA Kodama, Hidenori Koresawa, Eiji Hase, Takeo Minamikawa, Yu Tokizane, Takeo Minamikawa and Takeshi Yasui : 波長/角度変換光コムを用いた表面プラズモン共鳴法に関する検討, 第83回応用物理学会秋季学術講演会, 22p-C302-12, Sep. 2022.
51.	Kazuki Sadahiro, Yu Tokizane, Eiji Hase, Takeo Minamikawa, 諸橋功 and Takeshi Yasui : 光コムを用いた波長走査型デジタル・ホログラフィーに関する基礎研究(3) ~連続モード抽出10GHz光コムを用いた段差計測~, 第83回応用物理学会秋季学術講演会, 22p-C302-10, Sep. 2022.
52.	Eiji Hase, Takeo Minamikawa, Yu Tokizane and Takeshi Yasui : ブリルアン・ラマン散乱顕微鏡を用いた非アルコール性脂肪性肝疾患における脂質の分子物性解析(1) ~ブリルアン散乱顕微鏡の構築と肝組織のブリルアンイメージング~, 第83回応用物理学会秋季学術講演会, 21p-P03-5, Sep. 2022.
53.	MIYAMURA Shogo, Ryo Oe, Takuya Nakahara, Shota Okada, Taira Kajisa, Yu Tokizane, Takeo Minamikawa, Taka-aki Yano, 田上周路, Kunihiro Otsuka, Ayuko Sakane, Takuya Sasaki, Koji Yasutomo and Takeshi Yasui : 新型コロナウイルスNタンパク抗原のデュアル光コム・バイオセンシング, 第83回応用物理学会秋季学術講演会, 21a-A200-4, Sep. 2022.
54.	Yutaro Onishi, Takeo Minamikawa, Hidenori Koresawa, Hayata Tadamasa, Mayuko Shimizu, 森本友樹, Eiji Hase, Takeshi Yasui and Koichi Tsuneyama : ラマン顕微鏡を用いた非アルコール性脂肪性肝疾患における脂肪滴サイズと脂質分子物性の関係解析, 第83回応用物理学会秋季学術講演会, 20p-C301-8, Sep. 2022.
55.	Koshiro Hori, Takeo Minamikawa, Yoshiki Terao, Masami Shishibori and Takeshi Yasui : SVMを用いたラマンスペクトル解析法による末梢神経の選択的判別と判別根拠解明, 第83回応用物理学会秋季学術講演会, 20p-C301-7, Sep. 2022.
56.	Hayata Tadamasa, Takeo Minamikawa, 鈴木昭弘 and Takeshi Yasui : 脂肪酸投与により細胞内に形成された脂肪滴のラマン分光解析, 第83回応用物理学会秋季学術講演会, 20p-C301-6, Sep. 2022.
57.	Takeo Minamikawa, 原田義規, 高松哲郎, 森本幸裕, 川崎昌博 and 川崎三津夫 : リモートプラズモニック光増強ラマン分光法による生体組織イメージング, レーザー学会第566回研究会, Sep. 2022.
58.	Takeo Minamikawa : 分光学の病理学への展開 ∼医学に新しい価値観を創造する∼, 第100回バイオメクフォーラム21研究会, Jul. 2022.
59.	Katsuya SATO, Takeo Minamikawa and Takeshi Yasui : Observation of osteoblasts synthesized matrix under micro vibration using raman spectroscopy, 日本機械学会第34回バイオエンジニアリング講演会, 1P1-01, Jun. 2022.
60.	Koshiro Hori, Takeo Minamikawa, Yoshiki Terao, Masami Shishibori and Takeshi Yasui : SVMのラマン分光法への応用による末梢神経の選択的判別と判別根拠解明, 第69回応用物理学会春季学術講演会, 26q-E204-1, Mar. 2022.
61.	Kohta Seki, Hidenori Koresawa, Eiji Hase, Yu Tokizane, Taira Kajisa, Takeo Minamikawa and Takeshi Yasui : 近赤外光を用いた高速入射角走査型表面プラズモン共鳴センサーの開発, 第69回応用物理学会春季学術講演会, 26p-E302-9, Mar. 2022.
62.	Hayata Tadamasa, Takeo Minamikawa, Yoshiki Terao, Koshirou Hori and Takeshi Yasui : ラマン散乱分光法とPCAを用いた生体組織判別と判別根拠の推定, 第69回応用物理学会春季学術講演会, 26a-E204-2, Mar. 2022.
63.	Kazuki Sadahiro, Yu Tokizane, Eiji Hase, Takeo Minamikawa, 諸橋功 and Takeshi Yasui : 光コムを用いた波長走査型デジタル・ホログラフィーに関する基礎研究(2) ~モード抽出10GHz光コムの基礎検討~, 第69回応用物理学会春季学術講演会, 26a-E302-7, Mar. 2022.
64.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Yu Tokizane, ryo Oe, Hidenori Koresawa, Hirotsugu Yamamoto and Takeshi Yasui : 全視野デュアル光コム蛍光寿命顕微鏡の開発, 第69回応用物理学会春季学術講演会, 25a-E302-2, Mar. 2022.
65.	Yuki Ogura, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 偏光分解SHG顕微鏡を用いた目周り皮膚コラーゲンの配向解析, 第69回応用物理学会春季学術講演会, 25p-P08-2, Mar. 2022.
66.	KAJIWARA Shimpei, Takeo Minamikawa, Keishiroh Ohtani, 中野祥太, Eiji Hase and Takeshi Yasui : レーザー走査型光周波数コム顕微鏡による偏光,ToFの定量解析, 第69回応用物理学会春季学術講演会, 25a-E302-62, Mar. 2022.
67.	Tokiya Ohe, Hirofumi Hosokawa, Takeo Minamikawa, Takeshi Yasui and Katsuya SATO : Evaluation of osteoblasts synthesized substrate calcification by Raman Spectroscopy, 日本機械学会中国四国学生会第52回学生員卒業研究発表講演会予稿集, Mar. 2022.
68.	Kohta Seki, Hidenori Koresawa, Eiji Hase, Taira Kajisa, Takeo Minamikawa and Takeshi Yasui : 高速入射角走査型表面プラズモン共鳴センサーのバイオセンシング応用, レーザー学会学術講演会第42回年次大会, I03-13a-IX-02, Jan. 2022.
69.	MIYAMURA Shogo, Ryo Oe, Taira Kajisa, Yu Tokizane, Takeo Minamikawa, 田上周路 and Takeshi Yasui : デュアル屈折率センシング光コムを用いた温度補償型屈折率センシング, レーザー学会学術講演会第42回年次大会, E02-12p-V-04, Jan. 2022.
70.	Hidenori Koresawa, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : デュアルコム分光ジョーンズ行列偏光計による偏光光学特性の評価, レーザー学会学術講演会第42回年次大会, E01-12a-V-02, Jan. 2022.
71.	Kohta Seki, Hidenori Koresawa, Eiji Hase, Yu Tokizane, Taira Kajisa, Takeo Minamikawa and Takeshi Yasui : 角度走査型表面プラズモン共鳴センサーの高速化, LED総合フォーラム2022 in 徳島, P-18, Jan. 2022.
72.	Kazuki Sadahiro, Yu Tokizane, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 高速波長走査型デジタルホログラフィーのためのモード抽出型光コムの開発, LED総合フォーラム2022 in 徳島, P-16, Jan. 2022.
73.	Takeo Minamikawa : 深紫外光を用いた新型コロナウイルスの不活化, 第34回光ものづくりセミナー, Dec. 2021.
74.	Takeo Minamikawa : 深紫外LEDを用いた新型コロナウイルス不活化, 光とレーザーの科学技術フェア2021, Nov. 2021.
75.	Koshirou Hori, Takeo Minamikawa, Yoshiki Terao, Masami Shishibori and Takeshi Yasui : 判別根拠を明らかにする機械学習的ラマンスペクトル解析法の開発と末梢神経の選択的判別への応用, レーザ顕微鏡研究会第46回講演会, Nov. 2021.
76.	Takeo Minamikawa, Mayuko Shimizu, Hiroki Tanioka, Eiji Hase, Yuki Morimoto, Hiroki Takanari, Takeshi Yasui and Koichi Tsuneyama : ラマン散乱分光法を用いた非アルコール性脂肪性肝疾患の脂質分子構造イメージング解析, レーザ顕微鏡研究会第46回講演会, Nov. 2021.
77.	Takeo Minamikawa : ラマン散乱分光法による非アルコール性脂肪性肝疾患診断, Optics & Photonics Japan 2021, Oct. 2021.
78.	Kazuki Sadahiro, Yu Tokizane, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 光コムを用いた高速波長走査型デジタル・ホログラフィーに向けた基礎検討, Optics & Photonics Japan 2021, 28pE5, Oct. 2021.
79.	MIYAMURA Shogo, Ryo Oe, Taira Kajisa, Yu Tokizane, Takeo Minamikawa, 田上周路 and Takeshi Yasui : 屈折率センシング光コムにおける温度補償の検討, Optics & Photonics Japan 2021, 28pE1, Oct. 2021.
80.	Kohta Seki, Hidenori Koresawa, Eiji Hase, Taira Kajisa, Takeo Minamikawa and Takeshi Yasui : ガルバノ走査を用いた表面プラズモン共鳴バイオセンサーの高速化, Optics & Photonics Japan 2021, 28pD5, Oct. 2021.
81.	Takeo Minamikawa : 深紫外LEDを用いた新型コロナウイルスの不活化, InterOpto 2021, Oct. 2021.
82.	Takuya Nakahara, Ryo Oe, Taira Kajisa, Yu Tokizane, Takeo Minamikawa, Taue Shuji, Kunihiro Otsuka, Ayuko Sakane, Koji Yasutomo, Takuya Sasaki and Takeshi Yasui : 屈折率センシング光コムを用いたバイオセンシングに関する検討(4)~新型コロナウイルス(SARS-CoV-2)の検出~, 第82回応用物理学会秋季学術講演会予稿集, 13p-N322-7, Sep. 2021.
83.	Hiroki Tanioka, Takeo Minamikawa, Mayuko Shimizu, Yuki Morimoto, Hiroki Takanari, Yutaro Onishi, Eiji Hase, Takeshi Yasui and Koichi Tsuneyama : 表面増強ラマン散乱分光法を用いた非アルコール性脂肪肝疾患モデルの高感度ラマンイメージング, 第82回応用物理学会秋季学術講演会予稿集, 13a-N202-9, Sep. 2021.
84.	Seki Kota, (名) koresawa, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 高速入射角走査型表面プラズモン共鳴センサーの開発, 第82回応用物理学会秋季学術講演会予稿集, 11a-N106-8, Sep. 2021.
85.	Keishiroh Ohtani, Takeo Minamikawa, 中野祥太, Eiji Hase and Takeshi Yasui : 透過型光コム分光顕微鏡の位相安定性の改善, 第82回応用物理学会秋季学術講演会予稿集, 10p-N106-5, Sep. 2021.
86.	Hidenori Koresawa, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : デュアルコム分光ジョーンス行列偏光計を用いた偏光光学素子の計測, 第82回応用物理学会秋季学術講演会予稿集, 10p-N106-10, Sep. 2021.
87.	Kazuki Sadahiro, Yu Tokizane, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 光コムを用いた波長走査型デジタル・ホログラフィーに関する基礎研究, 第82回応用物理学会秋季学術講演会, 10p-N106-2, Sep. 2021.
88.	Hirofumi Hosokawa, Takeo Minamikawa, Takeshi Yasui and Katsuya SATO : Evaluation of composition and mechanical properties of culture osteoblast synthesized substrate by raman microscopy, 日本機械学会 2021年度年次大会講演論文, S021-05, Sep. 2021.
89.	Takeo Minamikawa, Takaaki Koma, 鈴木昭浩, Kentaro Nagamatsu, Takeshi Yasui, Koji Yasutomo and Masako Nomaguchi : 深紫外LEDを用いた新型コロナウイルスの不活化, 電気学会光・量子デバイス研究会「パワー光源システム技術研究会」, Jul. 2021.
90.	Takeo Minamikawa : 深紫外LEDを用いた新型コロナウイルスの不活化, OPIE'21(Optics Photonics International Exhibition 2021), Jun. 2021.
91.	Takeo Minamikawa, Mayuko Shimizu and Koichi Tsuneyama : Molecular structural imaging analysis for non-alcoholic fatty liver disease by Raman spectroscopy, The 57th Annual Meeting of the Japan Society of Hepatology, Jun. 2021.
92.	Takeo Minamikawa : 深紫外線LED技術と新型コロナウイルスの不活化への応用, 日本テクノセンター講演会, Apr. 2021.
93.	Takeo Minamikawa : 深紫外LEDを用いた新型コロナの不活化, 三重大学北勢サテライト研究会「紫外発光LEDの作製と応用に関する研究と社会実装」第2回セミナー, Mar. 2021.
94.	Hiroki Tanioka, Takeo Minamikawa, Mayuko Shimizu, Yuki Morimoto, Hiroki Takanari, Ryosuke Shiomi, Eiji Hase, Takeshi Yasui and Koichi Tsuneyama : 非アルコール性脂肪性肝炎診断に対するラマン顕微鏡法の適用可能性の検証計, 第68回応用物理学会春季学術講演会予稿集, 19a-Z04-9, Mar. 2021.
95.	Koshirou Hori, Takeo Minamikawa, Yoshiki Terao, Masami Shishibori and Takeshi Yasui : ラマン分光法とSVMを組み合わせた末梢神経の選択的判別と判別根拠の推定, 第68回応用物理学会春季学術講演会予稿集, 19a-Z04-8, Mar. 2021.
96.	Takuya Nakahara, Takeo Minamikawa, 田上周路, Taira Kajisa and Takeshi Yasui : 屈折率センシング光コムを用いたバイオセンシングに関する検討(3)~アビジン/ビオチン抗体抗原反応の検出~, 第68回応用物理学会春季学術講演会予稿集, 17a-Z08-10, Mar. 2021.
97.	Keishiroh Ohtani, Takeo Minamikawa, Shota Nakano, Eiji Hase and Takeshi Yasui : 透過型光コム分光顕微鏡の開発, 第68回応用物理学会春季学術講演会予稿集, 16a-Z08-10, Mar. 2021.
98.	Hidenori Koresawa, Maeda Kousuke, Takeo Minamikawa and Takeshi Yasui : デュアルコム分光ジョーンズ行列偏光計, 第68回応用物理学会春季学術講演会予稿集, 16a-Z08-11, Mar. 2021.
99.	Kazuki Furuya, Hirofumi Hosokawa, Eiji Hase, Takeo Minamikawa, Takeshi Yasui and Katsuya SATO : SHG / THG observation of osteoblastic matrix formation process subject to vibration stimuli, 日本機械学会中国四国支部第51回学生員卒業研究発表講演会, Mar. 2021.
100.	Takeo Minamikawa : 深紫外LEDによる新型コロナウイルス不活化の試み, LED総合フォーラム2021 in 徳島, オンライン, Feb. 2021.
101.	Takeo Minamikawa : ラマン散乱分光法による生体組織機能情報の可視化, レーザー学会学術講演会第41回年次大会, H01-19p-VII-02, Jan. 2021.
102.	Takeo Minamikawa : 深紫外LEDによるウイルス不活化への取り組みについて, 日本フォトニクス協議会(JPC)フォーラム12月定例会, Dec. 2020.
103.	Takeo Minamikawa : ラマン散乱分光法で実現する生体機能診断, さきがけ(光極限)公開シンポジウム, Dec. 2020.
104.	Takeo Minamikawa : Withコロナ時代に向けた深紫外LEDの活用法∼深紫外LEDによるウイルス不活化の試み∼, InterOpto 2021, Dec. 2020.
105.	Eiji Hase, Yu Tokizane, Takeo Minamikawa and Takeshi Yasui : 光コムシンセサイザーを用いたカスケードリンク型マルチ合成波長デジタルホログラフィ, 第18回医用分光学研究会, Nov. 2020.
106.	Takuya Nakahara, Ryo Oe, Takeo Minamikawa, 田上周路, Taira Kajisa and Takeshi Yasui : 屈折率センシング光コムの共振器ファイバー表面修飾を用いたバイオセンシング, Optics & Photonics Japan 2020, 17aD11, Nov. 2020.
107.	Ryo Oe, Takeo Minamikawa, 田上周路, 楠美友悟, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : デュアル屈折率センシング光コム, 第81回応用物理学会秋季学術講演会予稿集, 8p-Z19-13, Sep. 2020.
108.	Katsuya SATO, Yuta Kameyama, Hirofumi Hosokawa, Takeo Minamikawa and Takeshi Yasui : 培養骨芽細胞が産生する基質マトリクスの非線形光学顕微鏡による観察, Journal of Japanese Society of Bone Morphometry, Vol.30, No.1, S102, May 2020.
109.	Fumitoshi Yagishita, Junichi Tanigawa, Masaki Okamoto, Eiji Hase, Hiroki Takanari, Atsushi Tabata, Hideaki Nagamune, Takeo Minamikawa, Takeshi Yasui, Yasushi Imada and Yasuhiko Kawamura : Synthesis of Imidazopyridinium Salts Having Potential Application as Image-guided Photodynamic Therapy Agents, The 100th CSJ Annual Meeting, Mar. 2020.
110.	Yoshiki Terao, Takeo Minamikawa, Ryosuke Shiomi, Takahiko Mizuno and Takeshi Yasui : 多変量解析を駆使したラマン散乱分光法による末梢神経判別法の開発, 第67回応用物理学会春季学術講演会予稿集, 15p-B309-5, Mar. 2020.
111.	Takuya Tsuda, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 次元変換光コムを用いたスキャンレス・フルフィールド共焦点顕微鏡の開発(8) ~共焦点/位相接続による深さダナミックレンジの拡大~, 第67回応用物理学会春季学術講演会予稿集, 14a-B409-9, Mar. 2020.
112.	Takuya Nakahara, Ryo Oe, Takeo Minamikawa, 田上周路, Taira Kajisa and Takeshi Yasui : 屈折率センシング光コムを用いたバイオセンシングに関する検討(2) ~共振器内バイオセンサーによる繰り返し周波数シフト特性~, 第67回応用物理学会春季学術講演会予稿集, 14p-B409-10, Mar. 2020.
113.	Kohta Seki, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, 荻博次 and Takeshi Yasui : ピコ秒レーザー超音波を用いたバイオイメージング ∼非同期光サンプリング式ピコ秒レーザー超音波計測∼, 第67回応用物理学会春季学術講演会予稿集, 14p-B409-10, Mar. 2020.
114.	terao Yoshiki, Takeo Minamikawa, Shiomi Ryosuke, Takahiko Mizuno and Takeshi Yasui : 多変量解析を駆使したラマン散乱分光法による神経組織判別, LED総合フォーラム2020 in 徳島, P-@, Feb. 2020.
115.	Kosuke Maeda, Eiji Hase, Takahiko Mizuno, Takeo Minamikawa and Takeshi Yasui : In vivoヒト皮膚コラーゲン線維配向計測のための高速連続偏光分解SHG(第2高調波発生光)顕微鏡の開発, LED総合フォーラム2020 in 徳島, P-@, Feb. 2020.
116.	Takuya Nakahara, Ryo Oe, Takeo Minamikawa, 田上周路, Mikito Yasuzawa, Taira Kajisa, Kenzo Yamaguchi and Takeshi Yasui : バイオセンシング光コムのためのバイオセンサーの開発, LED総合フォーラム2020 in 徳島, P-12, Feb. 2020.
117.	Eiji Hase, Takeo Minamikawa, Shuji Miyamoto, Hirotsugu Yamamoto and Takeshi Yasui : ワンショット・フルフィールド共焦点顕微鏡を用いた植物モニタリング, レーザー学会学術講演会第40回年次大会, X03-22p-XI-03, Jan. 2020.
118.	Takeo Minamikawa : 分光学を駆使した新たな医療診断~組織機能を可視化する~, バイオインダストリー協会未来へのバイオ技術勉強会, Jan. 2020.
119.	Takeo Minamikawa : 光で見る・視る・診る~医療に向けた分光学, 地域産業人材育成講座「光産業の人材育成を目指すリカレント教育プログラム」キックオフセミナー, Dec. 2019.
120.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : デュアル光コムビートによる2次元周波数多重化照明を用いた蛍光寿命イメージング法の開発, Optics & Photonics Japan 2019, 5aB2, Dec. 2019.
121.	takuya nakahara, ryo oe, Takeo Minamikawa, 田上周路, Mikito Yasuzawa, Taira Kajisa, Kenzo Yamaguchi and Takeshi Yasui : バイオセンシング光コムのためのファイバーバイオセンサーの作製, Optics & Photonics Japan 2019, 5aB4, Dec. 2019.
122.	Masatomo Yamagiwa, Yu Tokizane, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 不透明物体の内部応力可視化に向けた位相シフトTHz デジタルホログラフィ計測, Optics & Photonics Japan 2019, 3pP30, Dec. 2019.
123.	Takuya Tsuda, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 光ファイバー増幅器によるスキャンレス・デュアル光コム顕微鏡の画像増幅, Optics & Photonics Japan 2019, 2aF2, Dec. 2019.
124.	Kosuke Maeda, Eiji Hase, Takahiko Mizuno, yuki ogura, Takeo Minamikawa and Takeshi Yasui : 高速連続偏光分解SHG顕微鏡を用いたヒト真皮コラーゲン線維のin situ深さ分解配向イメージング, Optics & Photonics Japan 2019, 2aF3, Dec. 2019.
125.	kazuki nitta, JIE CHEN, Takeo Minamikawa, 郑铮 and Takeshi Yasui : モード同期多重化ファイバーレーザー用いたアダプティブ・サンプリング式デュアルテラヘルツコム分光法の低圧ガス計測, Optics & Photonics Japan 2019, 2pD3, Dec. 2019.
126.	Takeo Minamikawa : がんの統合的診断・治療を目指した分子から組織のマルチスケール・バイブレーショナル光学顕微鏡の創成, 徳島大学研究クラスターシンポジウム, Nov. 2019.
127.	Takeo Minamikawa : 光コム顕微鏡~光を極限的に制御し，計測し，活用する~, 第23回光科学若手研究会, Nov. 2019.
128.	Yoshiki Terao, Takeo Minamikawa, Ryosuke Shiomi, Takahiko Mizuno and Takeshi Yasui : ラマン散乱分光法による生体組織の無染色組織判別法の開発, ポストLEDフォトニクス公開シンポジウム, Oct. 2019.
129.	Ryosuke Shiomi, Takeo Minamikawa and Takeshi Yasui : 疑似ライン照射ラマン顕微鏡の構築, ポストLEDフォトニクス公開シンポジウム, Oct. 2019.
130.	Shota Nakano, Takeo Minamikawa, Eiji Hase, 浅原彰文, Takahiko Mizuno, Katsuya SATO, Hirotsugu Yamamoto, Kaoru Minoshima and Takeshi Yasui : 光コム顕微鏡を用いた統合的光計測プラットホームの開発, ポストLEDフォトニクス公開シンポジウム, Oct. 2019.
131.	Takeo Minamikawa : 分光学を駆使した新たな医療診断~組織機能を可視化する~, 第20回日本光学会情報フォトニクス研究グループ研究会, Sep. 2019.
132.	Ryosuke Shiomi, Takeo Minamikawa, Ryo Oe, 谷口一徹, Takeshi Yasui and 太田博文 : ラマン・自家蛍光分光計測を用いた茶葉に与える抹茶製法の影響解析, 第80回応用物理学会秋季学術講演会, 21a-E206-8, Sep. 2019.
133.	Kosuke Maeda, Eiji Hase, Takahiko Mizuno, Takeo Minamikawa and Takeshi Yasui : 高速連続偏光分解SHGイメージングにおける測定深さ依存性の影響, 第80回応用物理学会秋季学術講演会, 21a-E206-9, Sep. 2019.
134.	Shota Nakano, Takeo Minamikawa, Eiji Hase, 浅原彰文, Takahiko Mizuno, Katsuya SATO, Hirotsugu Yamamoto, Kaoru Minoshima and Takeshi Yasui : レーザー走査型光コム分光顕微鏡による生体計測, 第80回応用物理学会秋季学術講演会, 20p-PA4-12, Sep. 2019.
135.	Takuya Tsuda, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 次元変換光コムを用いたスキャンレス・フルフィールド共焦点顕微鏡の開発(7)~ポスト光増幅イメージの特性評価~, 第80回応用物理学会秋季学術講演会, 20a-E205-9, Sep. 2019.
136.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : デュアル光コム顕微鏡によるスキャンレス蛍光イメージング(4) ∼蛍光寿命イメージング応用∼, 第80回応用物理学会秋季学術講演会, 20a-E205-11, Sep. 2019.
137.	Ryo Oe, Takeo Minamikawa, 田上周路, Naoya Kuse and Takeshi Yasui : 可飽和吸収ミラー型偏波保持ファイバー光コムを用いた屈折率センシング, 第80回応用物理学会秋季学術講演会, 20p-E205-8, Sep. 2019.
138.	Ryo Oe, Takeo Minamikawa, 田上周路, Naoya Kuse and Takeshi Yasui : マルチパラメータ測定に基づいた光コム屈折率センシングの高度化, 第80回応用物理学会秋季学術講演会, 20p-E205-7, Sep. 2019.
139.	Takuya Nakahara, Ryo Oe, Takeo Minamikawa, Mikito Yasuzawa, Taira Kajisa and Takeshi Yasui : 屈折率センシング光コムを用いたバイオセンシングに関する検討, 第80回応用物理学会秋季学術講演会, 20p-E205-6, Sep. 2019.
140.	Hidenori Koresawa, Kyuki Shibuya, Takeo Minamikawa and Takeshi Yasui : 高速デュアルコム偏光分光法を用いた動的現象の計測, 第80回応用物理学会秋季学術講演会, 20a-E205-10, Sep. 2019.
141.	Masatomo Yamagiwa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 位相シフトTHzデジタルホログラフィを用いた外力印加中の不透明物体の透過位相イメージング, 第80回応用物理学会秋季学術講演会, 19a-PA2-18, Sep. 2019.
142.	Yoshiki Terao, Takeo Minamikawa, Ryosuke Shiomi and Takeshi Yasui : 多変量解析を駆使したラマン散乱分光法による無染色組織判別, 生体医工学シンポジウム2019, 2P-12, Sep. 2019.
143.	Kosuke Maeda, Eiji Hase, Takahiko Mizuno, Takeo Minamikawa and Takeshi Yasui : 高速連続偏光分解SHG顕微鏡によるin situヒト皮膚コラーゲン線維配向イメージング, 生体医工学シンポジウム2019, 2A-39, Sep. 2019.
144.	Ryosuke Shiomi, Takeo Minamikawa and Takeshi Yasui : 分子イメージングのための疑似ライン照射ラマン顕微鏡の構築, 生体医工学シンポジウム2019, 2A-36, Sep. 2019.
145.	Takuya Tsuda, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : スキャンレスデュアル光コム顕微鏡を用いた動体サンプルの共焦点振幅・位相差イメージング, 生体医工学シンポジウム2019, 2A-35, Sep. 2019.
146.	Shota Nakano, Takeo Minamikawa, Eiji Hase, 浅原彰文, Takahiko Mizuno, Katsuya SATO, Hirotsugu Yamamoto, Kaoru Minoshima and Takeshi Yasui : レーザー走査型光コム定量位相差顕微鏡によるバイオイメージング, 生体医工学シンポジウム2019, 2A-29, Sep. 2019.
147.	Takeo Minamikawa : 分光学に基づくヒトに優しい医療センシング, 日本実験力学会2019年度年次講演会, Sep. 2019.
148.	Hidenori Koresawa, Marc GOURAYEB, Kyuki Shibuya, Takeo Minamikawa and Takeshi Yasui : デュアルコム分光法による高速分光偏光計測, 2019年度応用物理・物理系学会中国四国支部合同学術講演会, 3, Jul. 2019.
149.	Yoshiki Terao, Takeo Minamikawa, Ryosuke Shiomi, Takahiko Mizuno and Takeshi Yasui : 多変量解析を駆使したラマン散乱分光法による無染色組織判別, MEとバイオサイバネティックス研究会, Vol.119, No.0913-5685, 47-49, Jul. 2019.
150.	Kosuke Maeda, Eiji Hase, Takeo Minamikawa, Takahiko Mizuno, Yuki Ogura and Takeshi Yasui : 高速連続偏光分解SHG顕微鏡を用いたヒト真皮コラーゲン線維配向のin situ可視化, MEとバイオサイバネティックス研究会, Vol.119, No.0913-5685, 43-46, Jul. 2019.
151.	Yuta Kameyama, Yosuke Iki, Takeshi Matsumoto, Takeo Minamikawa, Takeshi Yasui and Katsuya SATO : Influence of intermittent vibration stimuli on osteoblasts matrix production, 第30回バイオフロンティア講演会講演論文集, 2A31, Jul. 2019.
152.	Takeo Minamikawa : 光コムを用いた分光エリプソメトリー, 第44回光学シンポジウム, Jun. 2019.
153.	Takeo Minamikawa : 医療応用を目指したラマン散乱分光法 ∼分子振動に基づく新たな無染色組織診断法∼, ものづくりライフイノベーションシンポジウム2019, Jun. 2019.
154.	Takeo Minamikawa : ラマン散乱分光法を用いた無染色分子組織診断, 第58回日本生体医工学会大会, Jun. 2019.
155.	Hidenori Koresawa, Marc GOURAYEB, Kyuki Shibuya, Takeo Minamikawa and Takeshi Yasui : デュアルコム分光偏光計測, 第63回システム制御情報学会研究発表講演会, GSc02-4, May 2019.
156.	Kazuki Nitta, Chen Jie, Takeo Minamikawa, Zheng Zheng and Takeshi Yasui : 2波長モード同期ファイバーレーザーとアダプティブ・サンプリングを用いたデュアル・テラヘルツコム分光法, 第63回システム制御情報学会研究発表講演会, GSc02-5, May 2019.
157.	Kazuki Nitta, JIE CHEN, Takeo Minamikawa, 郑铮 and Takeshi Yasui : 2波長モード同期ファイバーレーザーとアダプティブ・サンプリング式デュアルTHzコム分光法を用いた低圧ガス計測, 第66回応用物理学会春季学術講演会, 12a-S421-1, Mar. 2019.
158.	Hidenori Koresawa, Marc GOURAYEB, Kyuki Shibuya, Takeo Minamikawa and Takeshi Yasui : デュアルコム分光を用いた高速偏光計測, 第66回応用物理学会春季学術講演会, 11p-W935-2, Mar. 2019.
159.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : デュアル光コム顕微鏡によるスキャンレス蛍光イメージング(3) ∼ 蛍光イメージングSNRの改善 ∼, 第66回応用物理学会春季学術講演会, 11p-W935-4, Mar. 2019.
160.	Ryo Oe, Takeo Minamikawa, 田上周路, 深野秀樹, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : 屈折率センシング光コムを用いた液体サンプルの温度•濃度同時計測(2)~スペクトル計測による温度•濃度の算出~, 第66回応用物理学会春季学術講演会, 11a-W935-9, Mar. 2019.
161.	Ryo Oe, Takeo Minamikawa, 田上周路, 深野秀樹, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : 可飽和吸収ミラー型モード同期ファイバー光コム共振器による屈折率センシング, 第66回応用物理学会春季学術講演会, 11a-W935-10, Mar. 2019.
162.	Takuya Tsuda, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 次元変換光コムを用いたスキャンレス・フルフィールド共焦点顕微鏡の開発(6)~ポスト光増幅によるイメージSN比の向上~, 第66回応用物理学会春季学術講演会, 11p-W935-3, Mar. 2019.
163.	Masatomo Yamagiwa, Takeo Minamikawa, 諸橋功, Hirotsugu Yamamoto and Takeshi Yasui : モード操作光コムを用いたカスケードリンク型マルチ合成波長デジタル・ホログラフィの高速化(4) ~高精度形状計測~, 第66回応用物理学会春季学術講演会, 10p-W331-14, Mar. 2019.
164.	Eiji Hase, Takeo Minamikawa, Takahiko Mizuno, Yuki Ogura and Takeshi Yasui : 高速連続偏光分解SHG顕微鏡を用いたin situ真皮コラーゲン配向解析, 第66回応用物理学会春季学術講演会, 9p-W641-1, Mar. 2019.
165.	Yuto Fukuike, Takeo Minamikawa, Shota Nakano, Ryosuke Shiomi, Eiji Hase, Hirotsugu Yamamoto and Takeshi Yasui : 空間/波長変換を用いたワンショット共焦点顕微鏡による生体組織観察への応用, 第66回応用物理学会春季学術講演会, 9p-W641-2, Mar. 2019.
166.	Shota Nakano, Takeo Minamikawa, Eiji Hase, 浅原彰文, Takahiko Mizuno, Hirotsugu Yamamoto, Kaoru Minoshima and Takeshi Yasui : レーザー走査型光コム分光顕微鏡による偏光計測, 第66回応用物理学会春季学術講演会, 9p-W935-3, Mar. 2019.
167.	Katsuya SATO, Shota Okazawa, Yuta Kameyama, Takeshi Matsumoto, Takeo Minamikawa and Takeshi Yasui : Enhancement of osteoblastic matrix synthesis by using mechanical vibration stimuli, 第31回バイオエンジニアリング講演会論文集, 1F31, Dec. 2018.
168.	Takeo Minamikawa, 山本経尚, 原田義規, 山岡禎久, 田中秀央, 夜久均 and 髙松哲郎 : ラマン散乱分光法を用いたヒト心筋梗塞評価, 第16回医用分光学研究会, Nov. 2018.
169.	Takeo Minamikawa : 光コムを用いた分光エリプソメトリー法, Optics & Photonics Japan 2018, Nov. 2018.
170.	Takuya Tsuda, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : スキャンレスデュアル光コム顕微鏡を用いた動体サンプルの共焦点位相差イメージング, Optics & Photonics Japan 2018, 2aA4, Nov. 2018.
171.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : デュアル光コムビートの2 次元周波数多重化ビームを用いた蛍光イメージング法の開発, Optics & Photonics Japan 2018, 2aA5, Nov. 2018.
172.	Masatomo Yamagiwa, Takeo Minamikawa, 諸橋功, 関根徳彦, 寳迫巌, Hirotsugu Yamamoto and Takeshi Yasui : モード操作光コムを用いたマルチ合成波長デジタルホログラフィーによる形状計測, Optics & Photonics Japan 2018, 1aP12, Nov. 2018.
173.	Kazuki Nitta, JIE CHEN, Tatsuya Mizuguchi, Guoqing Hu, Takeo Minamikawa, 郑铮 and Takeshi Yasui : 2 波長デュアルル光コムファイバーレーザーによるアダプティブ・サンプリング式デュアルテラヘルツコム分光法, Optics & Photonics Japan 2018, 1pB13, Nov. 2018.
174.	Hidenori Koresawa, GOURAYEB Marc, Takeo Minamikawa and Takeshi Yasui : デュアルコム分光エリプソメトリーを用いた薄膜測定, Optics & Photonics Japan 2018, 1pB14, Nov. 2018.
175.	Masatomo Yamagiwa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 不透明物体計測のための位相シフトTHzデジタルホログラフィーの開発, Optics & Photonics Japan 2018, 31aP3, Oct. 2018.
176.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : デュアル光コム蛍光顕微鏡によるスキャンレス・フルフィールド蛍光イメージング法の開発, 第41回日本生体医工学会中国四国支部大会, Oct. 2018.
177.	Yuta Kameyama, Takeshi Matsumoto, Takeo Minamikawa, Takeshi Yasui and Katsuya SATO : Investigation of vibration condition to enhance osteoblasts proliferation and matrix mineralization, 第29回バイオフロンティア講演会論文集, 1A21, Oct. 2018.
178.	Masatomo Yamagiwa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 位相シフトTHzデジタルホログラフィによる不透明物体の透過振幅/位相イメージング, 第79回応用物理学会秋季学術講演会, 21a-212A-3, Sep. 2018.
179.	Kazuki Nitta, Jie Chen, Tatsuya Mizuguchi, Guoqing Hu, Takeo Minamikawa, 郑铮 and Takeshi Yasui : 2波長モード同期ファイバーレーザーを用いたアダプティブ・サンプリング式デュアルTHzコム分光法, 第79回応用物理学会秋季学術講演会, 21p-212A-3, Sep. 2018.
180.	Masatomo Yamagiwa, Takeo Minamikawa, 諸橋功, 関根徳彦, 寳迫巌, Hirotsugu Yamamoto and Takeshi Yasui : モード操作光コムを用いたカスケードリンク型マルチ合成波長デジタル・ホログラフィの高速化(3)∼高速スイッチング合成波長を用いた広ダイナミックレンジ形状計測∼, 第79回応用物理学会秋季学術講演会, 20p-431B-13, Sep. 2018.
181.	Ryo Oe, Takeo Minamikawa, 田上周路, 深野秀樹, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : 屈折率センシング光コムを用いた液体サンプルの温度・濃度同時計測, 第79回応用物理学会秋季学術講演会, 19a-438-3, Sep. 2018.
182.	Takuya Tsuda, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 次元変換光コムを用いたスキャンレス・フルフィールド共焦点顕微鏡の開発(5)∼共焦点位相差イメージングの高速化∼, 第79回応用物理学会秋季学術講演会, 19a-438-12, Sep. 2018.
183.	Ryosuke Shiomi, Takeo Minamikawa, Ryo Oe, 谷口一徹, Takeshi Yasui and 太田博文 : マルチモーダル分光計測を用いた茶葉に与える抹茶製法の影響分析, 第79回応用物理学会秋季学術講演会, 19p-438-8, Sep. 2018.
184.	Shota Nakano, Takeo Minamikawa, Eiji Hase, 浅原彰文, Takahiko Mizuno, Hirotsugu Yamamoto, Kaoru Minoshima and Takeshi Yasui : レーザー走査型共焦点光コム分光顕微鏡の開発, 第79回応用物理学会秋季学術講演会, 19p-438-9, Sep. 2018.
185.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : デュアル光コム顕微鏡によるスキャンレス蛍光イメージング(2) ∼520 nm帯光コムによる蛍光イメージング∼, 第79回応用物理学会秋季学術講演会, 19p-438-11, Sep. 2018.
186.	Hidenori Koresawa, Kyuki Shibuya, 浅原彰文, Takeo Minamikawa, Kaoru Minoshima and Takeshi Yasui : ロックイン検出型デュアル光コム分光法, 第79回応用物理学会秋季学術講演会, 18p-PA4-19, Sep. 2018.
187.	Katsuya SATO, Keita Fujimoto, Takeo Minamikawa and Takeshi Yasui : 20fsパルス幅レーザー照射による骨芽細胞へのフォトダメージ評価, 日本機械学会2018年年次大会, S0210103, Sep. 2018.
188.	Takeo Minamikawa : ノーベル賞から見るバイオメディカルイメージングの潮流, バイオエンジニアリング部門若手講演交流会, Jul. 2018.
189.	Ryo Oe, Kohsuke Nagai, Takeo Minamikawa, 田上周路, 深野秀樹, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : ファイバー光コム共振器の外乱/RF変換機能を用いた屈折率計測(2) ∼屈折率依存性繰り返し周波数シフトの観測∼, 第65回応用物理学会春季学術講演会, 20p-C303-1, Mar. 2018.
190.	Masatomo Yamagiwa, Takeo Minamikawa, 諸橋功, 関根徳彦, 寳迫巌, Hirotsugu Yamamoto and Takeshi Yasui : モード操作光コムを用いたカスケードリンク型マルチ合成波長, 第65回応用物理学会春季学術講演会, 19a-P2-6, Mar. 2018.
191.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : デュアル光コム顕微鏡によるスキャンレス蛍光イメージング, 第65回応用物理学会春季学術講演会, 19p-C303-14, Mar. 2018.
192.	Masatomo Yamagiwa, Fui Minamiji, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 位相シフト法を用いたTHzデジタルホログラフィグ, 第65回応用物理学会春季学術講演会, 19p-A402-13, Mar. 2018.
193.	Takashi Masuoka, Takashi Ogura, Takeo Minamikawa, Yoshiaki Nakajima, 山岡禎久, Kaoru Minoshima and Takeshi Yasui : センシングRFコムを用いた光音響波の計測, 第65回応用物理学会春季学術講演会, 19a-B303-2, Mar. 2018.
194.	Takeo Minamikawa and Takeshi Yasui : 光コムを用いた分光エリプソメトリー法, 第65回応用物理学会春季学術講演会, 18p-C303-6, Mar. 2018.
195.	Takeshi Yasui and Takeo Minamikawa : 第2高調波発生光(SHG)顕微鏡による生体コラーゲンのin situ可視化, レーザー学会学術講演会第38回年次大会, 24pII-3, Jan. 2018.
196.	Kazuki Nitta, Tatsuya Mizuguchi, Hu Guoqing, Takeo Minamikawa, Zheng Zheng and Takeshi Yasui : デュアル光コム分光のための2波長ファイバー光コム光源(2) ~デュアルTHzコム分光への応用~, レーザー学会学術講演会第38回年次大会, 24pIII-11, Jan. 2018.
197.	Takuya Sakaue, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 偏光分解 SHG(第2高調波発生光) 顕微鏡を用いたコラーゲン線維配向の評価, 第30回バイオエンジニアリング講演会, 2E-10, Dec. 2017.
198.	Takuya Sakaue, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 電気光学結晶を用いた連続偏光分解第2高調波発生光(SHG)顕微鏡の開発, 第2回フォトニクス研究会「光の極限を探る!」, PTM-21P, Dec. 2017.
199.	Ryo Oe, Kohsuke Nagai, Takeo Minamikawa, 田上周路, 深野秀樹, 中嶋義晶, Kaoru Minoshima and Takeshi Yasui : ファイバー光コム共振器の外乱/RF変換機能を用いた屈折率計測, 第2回フォトニクス研究会「光の極限を探る!」, PTM-22P, Dec. 2017.
200.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : スキャンレスデュアル光コム顕微鏡による共焦点位相差イメージングの高速化, Optics & Photonics Japan 2017, 2aA10, Nov. 2017.
201.	Takuya Sakaue, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 電気光学的偏光回転を用いた偏光分解第2高調波発生光(SHG)顕微鏡, Optics & Photonics Japan 2017, 2pA6, Nov. 2017.
202.	Takashi Oe, Kohsuke Nagai, Takeo Minamikawa, 田上周路, 深野秀樹, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : マルチモード干渉ファイバーセンシング光コムを用いた屈折率計測, Optics & Photonics Japan 2017, 1pB3, Nov. 2017.
203.	Masatomo Yamagiwa, Takayuki Ogawa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : オフアクシス型 THzデジタルホログラフィを用いた不透明物体のリアルタイム振幅/位相イメージング, Optics & Photonics Japan 2017, 31aP9, Oct. 2017.
204.	Takashi Masuoka, Takeo Minamikawa, Yoshiaki Nakajima, 山岡禎久, Kaoru Minoshima and Takeshi Yasui : 超音波センシング型ファイバー光コムの特性評価, Optics & Photonics Japan 2017, 31aB6, Oct. 2017.
205.	Takuya Sakaue, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 偏光分解SHG(第2高調波発生光)顕微鏡を用いたコラーゲン線維配向計測, 第28回バイオフロンティア講演会, 1B11, Oct. 2017.
206.	Kazuma Takeichi, Takeo Minamikawa and Takeshi Yasui : SHG(第2高調波発生光)画像自己相関法を用いた真皮コラーゲン線維分布の定量化, 第28回バイオフロンティア講演会, 1B13, Oct. 2017.
207.	Takashi Masuoka, Takashi Ogura, Takeo Minamikawa, Yoshiaki Nakajima, 山岡禎久, Kaoru Minoshima and Takeshi Yasui : 光周波数コムを用いた光超音波イメージングに関する基礎研究, 第28回バイオフロンティア講演会, 1B16, Oct. 2017.
208.	Takeo Minamikawa : フルフィールド共焦点光コム顕微鏡, 日本オプトメカトロニクス協会「最新レーザー・赤外応用技術」セミナー, Oct. 2017.
209.	Kohsuke Atsuta, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : コンパクト第2高調波発生光顕微鏡の開発, 第40回日本生体医工学会中国四国支部大会, IV-6, Oct. 2017.
210.	Takeo Minamikawa, Yi-Da Hsieh, Kyuki Shibuya, Yoshiki Kaneoka, Sho Okubo, Hajime Inaba, Yasuhiro Mizurani, Tetsuo Iwata and Takeshi Yasui : デュアル光コム分光法を用いた分光エリプソメトリーの開発, 2017年度精密工学会秋季大会学術講演会, P44, Sep. 2017.
211.	Takeo Minamikawa : 光コムによる共焦点振幅・位相顕微鏡, 2017年度精密工学会秋季大会, Sep. 2017.
212.	Masatomo Yamagiwa, Takeo Minamikawa, 諸橋功, 関根徳彦, 寳迫巌, Hirotsugu Yamamoto and Takeshi Yasui : モード操作光コムを用いたカスケードリンク型マルチ合成波長デジタル・ホログラフィの高速化, 第78回応用物理学会秋季学術講演会, 8a-PB1-2, Sep. 2017.
213.	Masatomo Yamagiwa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 光周波数コム参照型シンセサイザを光源としたカスケード・リンク多波長デジタルホログラフィによる段差計測, 第78回応用物理学会秋季学術講演会, 8a-PB1-1, Sep. 2017.
214.	Takayuki Ogawa, Fui Minamiji, Masatomo Yamagiwa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : フルフィールドTHzデジタル・ホログラフィーを用いた不透明物体のリアルタイム振幅/位相イメージング, 第78回応用物理学会秋季学術講演会, 8p-A405-11, Sep. 2017.
215.	Takashi Masuoka, Takashi Ogura, Takeo Minamikawa, Yoshiaki Nakajima, 山岡禎久, Kaoru Minoshima and Takeshi Yasui : ファイバー型光コム共振器を用いたマルチダイナミックレンジひずみセンシング, 第78回応用物理学会秋季学術講演会, 7a-C14-7, Sep. 2017.
216.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 次元変換光コムを用いたスキャンレス・フルフィールド共焦点顕微鏡の開発(4)~2次元共焦点位相イメージング~, 第78回応用物理学会秋季学術講演会, 6p-A414-11, Sep. 2017.
217.	Ryo Oe, Kohsuke Nagai, Takeo Minamikawa, 田上周路, 深野秀樹, Yoshiaki Nakajima, Kaoru Minoshima and Takeshi Yasui : ファイバー光コム共振器の外乱/RF変換機能を用いた屈折率計測, 第78回応用物理学会秋季学術講演会, 6a-A414-3, Sep. 2017.
218.	Okazawa Shota, Takeshi Matsumoto, Takeshi Yasui, Takeo Minamikawa and Katsuya SATO : 骨芽細胞のコラーゲン産生における振動・ストレッチ複合刺激の影響, 日本機械学会2017年年次大会, S0210201, Sep. 2017.
219.	Takeo Minamikawa : 光コムを用いた精密計測への応用, 第388回精密工学会講習会「精密光計測の基礎ー干渉から光コムまでー」, Jul. 2017.
220.	Takeo Minamikawa : ラマン分光センシング ∼分子振動に基づく新たな無染色組織診断法∼, Translational Research Center (TRC) セミナー, Jun. 2017.
221.	Takashi Masuoka, Takashi Ogura, Takeo Minamikawa, Yoshiaki Nakajima, 山岡禎久, Kaoru Minoshima and Takeshi Yasui : ファイバー型光周波数コムを用いた超音波センサーの開発, 第64回応用物理学会春季学術講演会, 14p-514-5, Mar. 2017.
222.	Masatomo Yamagiwa, Takayuki Ogawa, Yusuke Kawahito, Clement TROVATO, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 光コム参照型シンセサイザを用いたカスケードリンク多波長デジタルホログラフィ, 第64回応用物理学会春季学術講演会, 14p-F205-8, Mar. 2017.
223.	Tatsuya Mizuguchi, Guoqing Hu, Takeo Minamikawa, 郑铮 and Takeshi Yasui : 2波長独立モード同期ファイバーレーザーを用いた非同期光サンプリング式テラヘルツ時間領域分光法, 第64回応用物理学会春季学術講演会, 15a-211-2, Mar. 2017.
224.	Takeo Minamikawa : 医療応用を目指したラマン散乱分光法, 光材料・応用技術研究会第4回研究会, Mar. 2017.
225.	Shota Okazawa, Takeshi Matsumoto, Takeshi Yasui, Takeo Minamikawa and Katsuya SATO : Enhancement of osteoblastic collagen synthesis under combined vibration and stretching stimulation, 日本機械学会中国四国支部第55期総会・講演会講演論文集, Feb. 2017.
226.	Takeo Minamikawa, Daiki Nagai, Takaaki Kaneko, Ittetsu Taniguchi, Mariko Ando, Ryo Akama and Kenji Takenaka : 浮世絵技法の復元的研究のための光計測・画像解析基盤技術の創出, 文部科学省共同利用・共同研究拠点日本文化資源デジタル・アーカイブ研究拠点 2016年度成果発表会, Feb. 2017.
227.	Takeo Minamikawa : デュアル光コム顕微鏡, レーザー学会学術講演会第37回年次大会, Jan. 2017.
228.	Shuji Miyamoto, Eiji Hase, Hirotsugu Yamamoto, Takeshi Yasui and Takeo Minamikawa : 波長/空間変換を用いたスキャンレス共焦点レーザー顕微鏡の開発, レーザー学会学術講演会第37回年次大会, Jan. 2017.
229.	Takayuki Ogawa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : テラヘルツ・ディジタルホログラフィを用いた3次元形状計測, レーザー学会学術講演会第37回年次大会, Jan. 2017.
230.	Eiji Hase, Takeo Minamikawa, Shuji Miyamoto, Hirotsugu Yamamoto and Takeshi Yasui : スキャンレスデュアル光コム顕微鏡による共焦点位相イメージング, レーザー学会学術講演会第37回年次大会, Jan. 2017.
231.	Tatsuya Mizuguchi, Guoqing Hu, Takeo Minamikawa, Tsutomu Araki, 郑铮 and Takeshi Yasui : デュアル光コム分光のための2波長ファイバー光コム光源, レーザー学会学術講演会第37回年次大会, Jan. 2017.
232.	Takashi Masuoka, Takashi Ogura, Takeo Minamikawa, Yoshiaki Nakajima, 山岡禎久, Kaoru Minoshima and Takeshi Yasui : 光音響波検出のためのRF変換ファイバー光コムの開発, レーザー学会学術講演会第37回年次大会, Jan. 2017.
233.	Shuji Miyamoto, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 波長分散素子を用いたスキャンレス共焦点レーザー顕微鏡の開発, 第1回フォトニクス研究会, Dec. 2016.
234.	Tatsuya Mizuguchi, Guoqing Hu, Takeo Minamikawa, 郑铮 and Takeshi Yasui : デュアルTHzコム分光のための2波長モード同期ファイバーレーザー, 第1回フォトニクス研究会, Dec. 2016.
235.	Takayuki Ogawa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : テラヘルツ波を用いたディジタルホログラフィによる3次元計測, 第1回フォトニクス研究会, Dec. 2016.
236.	Takashi Masuoka, Takashi Ogura, Takeo Minamikawa, Yoshiaki Nakajima, 山岡禎久, Kaoru Minoshima and Takeshi Yasui : 光音響波検出のためのRF変換ファイバー光コムの開発, 第1回フォトニクス研究会, Dec. 2016.
237.	Guoqing Hu, Tatsuya Mizuguchi, Takeo Minamikawa, Zheng Zheng and Takeshi Yasui : A free-running, dual-wavelength, mode-locked Er:fiber laser based real-time determination of absolute frequency of continuous-wave terahertz radiation, 第1回フォトニクス研究会, Dec. 2016.
238.	Takeshi Yasui, Tatsuya Mizuguchi, Guoqing Hu, Takeo Minamikawa and 郑铮 : デュアル・テラヘルツ・コム分光を簡略化する2色モード同期ファイバーレーザー, テラヘルツ科学の最先端Ⅲ, Nov. 2016.
239.	Takayuki Ogawa, トロヴァトクレモン, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 光シンセサイザを用いた多波長ディシタルホログラフィ計測, Optics&Photonics Japan2016, 2aE1, Nov. 2016.
240.	Eiji Hase, Shuji Miyamoto, Hirotsugu Yamamoto, Takeshi Yasui and Takeo Minamikawa : 光コムを用いた共焦点レーザー走査型顕微鏡の開発, Optics&Photonics Japan2016, 2aA8, Nov. 2016.
241.	Takeo Minamikawa, Takashi Masuoka, Takashi Ogura, Yoshiaki Nakajima, 山岡禎久, Kaoru Minoshima and Takeshi Yasui : 光コムセンシングキャビティによる超音波計測, Optics & Photonics Japan 2016, 2pD6, Nov. 2016.
242.	Kyuki Shibuya, Takeo Minamikawa, Yasuhiro Mizurani, Takeshi Yasui and Tetsuo Iwata : デュアルコム分光シングルピクセルイメージング, Optics&Photonics Japan2016, 1aE3, Oct. 2016.
243.	Eiji Hase, Takeo Minamikawa, Shuji Miyamoto, Hirotsugu Yamamoto and Takeshi Yasui : スキャンレスデュアル光コム顕微鏡を用いた共焦点位相差イメージング, Optics&Photonics Japan2016, 2aA7, Oct. 2016.
244.	Eiji Hase, Takeo Minamikawa, Daisuke Yonekura, Katsuya SATO, Mitsuhiko Takahashi and Takeshi Yasui : SHG顕微鏡を用いた腱修復におけるコラーゲン配向解析, Optics&Photonics Japan2016, 2aA4, Oct. 2016.
245.	Oki Matsubara, Eiji Hase, Takeo Minamikawa, Takeshi Yasui and Katsuya SATO : in vivo analysis of collagen fiber orientation produced by cyclically stretched osteoblast like cells with polarization-solved SHG microscopy, 第27回バイオフロンティア講演会講演論文集, 101-102, Oct. 2016.
246.	Takuya Sakaue, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 偏光分解第2高調波発生光顕微鏡を用いた組織コラーゲン配向の計測, 第39回日本生体医工学会中国四国支部大会講演抄録, II-1, Oct. 2016.
247.	Eiji Hase, Takeo Minamikawa, Katsuya SATO, Daisuke Yonekura, Mitsuhiko Takahashi and Takeshi Yasui : 偏光分解SHG(第2高調波発生光)顕微鏡を用いた修復腱におけるコラーゲン配向解析, 第39回日本生体医工学会中国四国支部大会講演抄録, I-7, Oct. 2016.
248.	Shuji Miyamoto, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 波長/空間変換およびマルチチャネル分光器を用いたワンショット・フルフィールド共焦点光学顕微鏡の開発, 第39回日本生体医工学会中国四国支部大会講演抄録, II-1, Oct. 2016.
249.	Yusuke Kawahito, クレモントロバト, Takayuki Ogawa, Takeo Minamikawa and Takeshi Yasui : 2波長デジタルホログラフィーを用いたバイオイメージング, 第39回日本生体医工学会中国四国支部大会講演抄録, II-2, Oct. 2016.
250.	Oki Matsubara, Eiji Hase, Takeo Minamikawa, Takeshi Yasui and Katsuya SATO : 偏光分解SHG顕微鏡を用いた繰り返し伸縮刺激を受ける骨芽細胞産生コラーゲンのin vivo線維配向解析, 第39回日本生体医工学会中国四国支部大会講演抄録, 17, Oct. 2016.
251.	Yuki Ogura, Kohsuke Atsuta, Eiji Hase, Takeo Minamikawa and Takeshi Yasui : 第2高調発生光顕微鏡の小型化, 生体医工学シンポジウム2016, 2P-5-8, Sep. 2016.
252.	Eiji Hase, Takeo Minamikawa, Katsuya SATO, Daisuke Yonekura, Mitsuhiko Takahashi and Takeshi Yasui : SHG顕微鏡を用いた腱修復の観測, 生体医工学シンポジウム2016, 2P-5-6, Sep. 2016.
253.	Yi-Da Hsieh, Shota Nakamura, Takeo Minamikawa, フランシスヒンデル and Takeshi Yasui : 動的THzガス分光とマルチピークフィッティングを用いた煙混在ガスの定量分析, 第77回応用物理学会秋季学術講演会予稿集, 16a-B2-9, Sep. 2016.
254.	Tatsuya Mizuguchi, Guoqing Hu, Takeo Minamikawa, 郑铮 and Takeshi Yasui : 2波長モード同期ファイバーレーザーを用いたデュアルTHzコム参照型THz絶対周波数計測, 第77回応用物理学会秋季学術講演会予稿集, 16a-B2-10, Sep. 2016.
255.	Eiji Hase, Shuji Miyamoto, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 次元変換光コムを用いたスキャンレス・フルフィールド共焦点顕微鏡の開発(3)~2次元共焦点イメージの取得~, 第77回応用物理学会秋季学術講演会予稿集, 15a-C42-6, Sep. 2016.
256.	Takashi Masuoka, Takashi Ogura, Takeo Minamikawa, Yoshiaki Nakajima, 山岡禎久, Kaoru Minoshima and Takeshi Yasui : ファイバー光コム型超音波センサーに関する基礎研究, 第77回応用物理学会秋季学術講演会予稿集, 15p-C32-7, Sep. 2016.
257.	Eiji Hase, Shuji Miyamoto, Hirotsugu Yamamoto, Takeshi Yasui and Takeo Minamikawa : 共焦点レーザー走査型光コムの開発, 第77回応用物理学会秋季学術講演会予稿集, 15p-C32-8, Sep. 2016.
258.	Kyuki Shibuya, Takeo Minamikawa, Yasuhiro Mizurani, Takeshi Yasui and Tetsuo Iwata : スキャンレスデュアルコム分光イメージング法の提案, 第77回応用物理学会秋季学術講演会予稿集, 15p-C32-4, Sep. 2016.
259.	Takeo Minamikawa : 術中医療センシングを目指したラマン散乱分光法, BioOpt Japan 2016, Sep. 2016.
260.	Takeo Minamikawa, Eiji Hase, Shuji Miyamoto, Yi-Da Hsieh, Yasuhiro Mizurani, Hirotsugu Yamamoto and Takeshi Yasui : 光コムの波長/空間次元変換を援用したスキャンレス共焦点光学顕微鏡, 2016年度精密工学会秋季大会学術講演会, B18, Sep. 2016.
261.	Takeo Minamikawa, Takashi Ogura, Takashi Masuoka, Yoshiaki Nakajima, 山岡禎久, Kaoru Minoshima and Takeshi Yasui : ファイバー光コム共振器によるひずみセンシング, 2016年度精密工学会秋季大会学術講演会, B62, Sep. 2016.
262.	Takeo Minamikawa, Takashi Ogura, Takashi Masuoka, Yoshiaki Nakajima, Yoshihisa Yamaoka, Kaoru Minoshima and Takeshi Yasui : Strain sensing with fiber-based optical frequency comb cavity, Proceedings of 57th Meeting on Lightwave Sensing Technology, 145-150, Jun. 2016.
263.	Takeo Minamikawa and Takeshi Yasui : 周波数コムを用いたTHz周波数標準技術の構築, 超高速光エレクトロニクス研究会, Apr. 2016.
264.	Tatsuya Mizuguchi, Kenta Hayashi, Takeo Minamikawa and Takeshi Yasui : 非制御フェムト秒レーザー励起フォトキャリアTHzコムを用いたCW-THz波のリアルタイム絶対周波数計測, 第63回応用物理学会春季学術講演会予稿集, 22a-H135-13, Mar. 2016.
265.	Guoqing Hu, Tatsuya Mizuguchi, Takeo Minamikawa, 郑铮 and Takeshi Yasui : デュアルTHzコム計測のための2波長モード同期Erファイバーレーザー, 第63回応用物理学会春季学術講演会予稿集, 22a-H135-12, Mar. 2016.
266.	Takayuki Ogawa, Takeo Minamikawa, Takeshi Yasui and Hirotsugu Yamamoto : THz量子カスケードレーザと2次元非冷却マイクロボロメータを用いたテラヘルツディジタルホログラフィ, 第63回応用物理学会春季学術講演会予稿集, 22a-H135-6, Mar. 2016.
267.	Takeo Minamikawa, Yi-Da Hsieh, Kyuki Shibuya, Yoshiki Kaneoka, Sho Okubo, Hajime Inaba, Yasuhiro Mizurani, Takeshi Yasui and Tetsuo Iwata : デュアル光コム分光エリプソメトリー, 第63回応用物理学会春季学術講演会予稿集, 21p-P15-8, Mar. 2016.
268.	Kohsuke Atsuta, Eiji Hase, Takeo Minamikawa, 吉木啓介 and Takeshi Yasui : SHG(第二高調波発生)顕微鏡の小型化, 第63回応用物理学会春季学術講演会予稿集, 21p-S422-7, Mar. 2016.
269.	Eiji Hase, Shuji Miyamoto, Yi-Da Hsieh, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 次元変換光コムを用いたスキャンレス・フルフィールド共焦点顕微鏡の開発(2)~2次元波長分散光学系の構築~, 第63回応用物理学会春季学術講演会予稿集, 21a-H116-11, Mar. 2016.
270.	Shuji Miyamoto, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 波長/1D空間変換および共焦点スリットを用いたフルフィールド・スキャンレス共焦点レーザー顕微鏡の開発, 第63回応用物理学会春季学術講演会予稿集, 20p-H116-9, Mar. 2016.
271.	Takeshi Yasui, Shuji Miyamoto, Eiji Hase, Takeo Minamikawa, Yasuhiro Mizurani and Hirotsugu Yamamoto : 共焦点スリットと波長/空間変換を用いたスキャンレス・フルフィールド共焦点レーザー顕微鏡の開発, 2016年度精密工学会春季大会学術講演会, T66, Mar. 2016.
272.	Keita Fujimoto, Ohki Matsubara, Eiji Hase, Takeo Minamikawa, Yuki Ogura, Takeshi Yasui and Katsuya SATO : Enhancemnet of fibroblasts collagen synthesis by cyclic stretch stimulation, 日本機械学会中国四国支部第46回学生員卒業研究発表講演会, 816, Mar. 2016.
273.	Takeo Minamikawa, 永井大規, 金子貴昭, 谷口一徹, 赤間亮 and 竹中健司 : 浮世絵技法の復元的研究のための光計測・画像解析基盤技術の創出, 文部科学省共同利用・共同研究拠点日本文化資源デジタル・アーカイブ研究拠点全体カンファレンス, Feb. 2016.
274.	Takeo Minamikawa, 原田義規 and 高松哲郎 : ラマン分光法に基づく心筋梗塞評価法, 第13回医用分光学研究会, Dec. 2015.
275.	Eiji Hase, Shuji Miyamoto, Takeo Minamikawa, Yi-Da Hsieh, Hirotsugu Yamamoto and Takeshi Yasui : 光コムを用いたスキャンレス共焦点顕微鏡の開発ー共焦点ライニメージングへの応用ー, Optics & Photonics Japan 2015, 28aC3, Oct. 2015.
276.	Oki Matsubara, Eiji Hase, Takeo Minamikawa, Takeshi Yasui and Katsuya SATO : 繰り返し伸縮刺激下における骨芽細胞産生コラーゲンのSHGイメージングによる評価, Optics & Photonics Japan 2015, 28aC8, Oct. 2015.
277.	Eiji Hase, Takeo Minamikawa, Katsuya SATO, Mitsuhiko Takahashi and Takeshi Yasui : SHG(第2高調波発生光)顕微鏡を用いた腱修復状態の観察, Optics & Photonics Japan 2015, 28aC9, Oct. 2015.
278.	Takayuki Ogawa, ダヒイブラヒム, Takeo Minamikawa, Takeshi Yasui and Hirotsugu Yamamoto : THz量子カスケードレーザーと2次元非冷却マイクロボロメーターを用いたテラヘルツディジタルホログラフィー, Optics & Photonics Japan 2015, 28aE9, Oct. 2015.
279.	Shuji Miyamoto, Eiji Hase, Takeo Minamikawa, Yi-Da Hsieh, Hirotsugu Yamamoto and Takeshi Yasui : 波長/空間変換に基づくマルチチャネル分光器型ワンショット共焦点顕微鏡, Optics & Photonics japan 2015, 30pD2, Oct. 2015.
280.	Shuji Miyamoto, Eiji Hase, Takeo Minamikawa, Yi-Da Hsieh, Hirotsugu Yamamoto and Takeshi Yasui : 波長/1D空間変換によるビーム走査フリーなラインフィールド共焦点顕微鏡, 第76回応用物理学会秋季学術講演会, 14a-2E-8, Sep. 2015.
281.	Eiji Hase, Shuji Miyamoto, Takeo Minamikawa, Yi-Da Hsieh, Hirotsugu Yamamoto and Takeshi Yasui : 次元変換光コムを用いたスキャンレス・フルフィールド共焦点顕微鏡の開発(1)~共焦点ラインイメージの取得~, 第76回応用物理学会秋季学術講演会, 13p-2G-14, Sep. 2015.
282.	Takeo Minamikawa, 永井大規, 金子貴昭, 谷口一徹, 赤間亮 and 竹中健司 : 光学顕微鏡でみる浮世絵の世界 (技術実習), 文部科学省共同利用・共同研究拠点日本文化資源デジタル・アーカイブ研究拠点ワークショップ, Jul. 2015.
283.	Takeo Minamikawa, 永井大規, 金子貴昭, 谷口一徹, 赤間亮 and 竹中健司 : 浮世絵技法の復元的研究のための光計測・画像解析基盤技術の創出, 文部科学省共同利用・共同研究拠点日本文化資源デジタル・アーカイブ研究拠点国際シンポジウム, Jul. 2015.
284.	Takeo Minamikawa, 山本経尚, 原田義規, 田中秀央 and 高松哲郎 : ラマン散乱分光法を用いた新たなヒト心筋梗塞評価法, 第12回日本病理学会カンファレンス, Jul. 2015.
285.	Takeo Minamikawa, 永井大規, 金子貴昭, 谷口一徹, 赤間亮 and 竹中健司 : 浮世絵技法の復元的研究のための光計測・画像解析基盤技術の創出, 祇園祭デジタルミュージアム展2015, Jul. 2015.
286.	Takeo Minamikawa, 谷口一徹, 竹中健司, 永井大規 and 金子貴昭 : 浮世絵技法の復元的研究のための光計測・画像解析基盤技術の創出, 立命館大学アート・リサーチセンター日本文化資源デジタル・アーカイブ研究拠点全体カンファレンス, Mar. 2015.
287.	Takeo Minamikawa, Yoshinori Harada and Tetsuro Takamatsu : 医療応用を目指したラマン散乱分光法による生体組織センシング, 日本分光学会赤外ラマン分光部会「第7回シンポジウム」, Jan. 2015.
288.	Takeo Minamikawa : 医療応用を目指したラマン散乱分光法, 量子エレクトロニクス研究会「バイオ・メディカルフォトニクスII」, Dec. 2014.
289.	Takeo Minamikawa, 原田義規 and 高松哲郎 : ラマン散乱分光によるex vivo末梢神経の無染色・選択的検出, 第55回日本組織細胞化学会総会・学術集会, Sep. 2014.
290.	Takeo Minamikawa, 金子貴昭, 谷口一徹, 竹中健司 and 永井大規 : 浮世絵技法の復元的研究のための光計測・画像解析基盤技術の創出, 立命館大学アート・リサーチセンター日本文化資源デジタル・アーカイブ研究拠点キックオフシンポジウム, Sep. 2014.
291.	Takeo Minamikawa, 原田義規 and 高松哲郎 : ラマンスペクトル解析による末梢神経の選択的検出, 第53回日本生体医工学会大会, Jun. 2014.
292.	Takeo Minamikawa, 原田義規 and 髙松哲郎 : 神経温存手術補助を目指したラマン散乱分光による末梢神経検出法, 最先端光計測とライフサイエンスの近未来-バイオ・ラマン2017 - [4], May 2014.
293.	Takeo Minamikawa : ラマン散乱分光法の医学応用 ~分子を捉える新たな無染色イメージング法~, 第6回Translational Research Center (TRC) セミナー, Feb. 2014.
294.	Takeo Minamikawa, 原田義規 and 高松哲郎 : 線形・非線形ラマン散乱分光法の医学への応用, 第36回日本分子生物学会年会, Dec. 2013.
295.	Takeo Minamikawa : 顕微ラマン散乱分光法の医学・生物学応用, 第22回日本バイオイメージング学会学術集会, Sep. 2013.
296.	Takeo Minamikawa : 線形・非線形ラマン顕微鏡∼医学・生物学の応用を目指して∼, 最先端光計測とライフサイエンスの近未来-バイオ・ラマン2017 - [2], Oct. 2012.
297.	Takeo Minamikawa and 高松哲郎 : ラマン散乱の医療応用, 185委員会 2012年度研究会, Feb. 2012.
298.	Takeo Minamikawa : 多焦点CARS顕微鏡による生細胞の無染色・分子選択的・高速イメージング, 日本分光学会関西支部「第25回最近の分光学の進歩に関する講演会」日本分光学会赤外ラマン分光部会「第6回シンポジウム」, Nov. 2011.
299.	Takeo Minamikawa : 非線形ラマン顕微鏡によるバイオイメージング, BioMechForum21, Jun. 2011.

Et cetera, Workshop:

1.	HIROKI Kitahama, Akira Emoto, Akihiro Suzuki, Atsuo Ochi, Takeo Minamikawa, Rei Nakamura and Takeshi Yasui : 各種紫外光源の定量的殺菌効果推定手順と測定条件における評価への影響について, 次世代光フォーラム2023 in 徳島, P-20, Feb. 2023.
2.	TOMOYA Okabe, Takeo Minamikawa, 大谷圭史朗, KAJIWARA Shimpei, Eiji Hase and Takeshi Yasui : 光コムを用いた透過型ステージ走査型顕微鏡による複数の光学パラメーターの同時評価, 次世代光フォーラム2023 in 徳島, P-13, Feb. 2023.
3.	TOMOHIRO Tamaki, Takeo Minamikawa, Eiji Hase, Mayuko Shimizu, Yuki Morimoto, Akihiro Suzuki, Takeshi Yasui, 中村聡子, Akemi Tsutsui, 高口浩一 and Koichi Tsuneyama : ヒト非アルコール性脂肪性肝疾患における超早期肝線維化のSHG 偏光顕微鏡解析, 次世代光フォーラム2023 in 徳島, P-12, Feb. 2023.
4.	KAZUKI Yasumaru, Takeo Minamikawa, Eiji Hase, 清水真裕子, Takeshi Yasui and Koichi Tsuneyama : 非アルコール性脂肪性肝疾患モデルマウスに蓄積した脂肪滴の物性解明, 次世代光フォーラム2023 in 徳島, P-11, Feb. 2023.
5.	YUYA Kodama, Hidenori Koresawa, Eiji Hase, Yu Tokizane, Takeo Minamikawa and Takeshi Yasui : 波長/角度変換光コムSPR(表面プラズモン共鳴法)における入射角度範囲の拡大, 次世代光フォーラム2023 in 徳島, P-7, Feb. 2023.
6.	SOTA Inoue, Takeo Minamikawa, Hiroki Tanioka, Takeshi Yasui, 森本幸裕, 川崎昌博 and 川崎三津夫 : 金属との近接を必要としないリモートプラズモニック増強ラマン分光法における銀ナノ粒子の効果, 次世代光フォーラム2023 in 徳島, P-6, Feb. 2023.
7.	Kohta Seki, Takeo Minamikawa, 荻博次 and Takeshi Yasui : 光音響波シンセサイザーに関する検討, LED総合フォーラム2021 in 徳島, P-16, Feb. 2021.
8.	Yoshiki Terao, Takeo Minamikawa and Takeshi Yasui : 主成分分析を駆使したラマン散乱分光法による神経組織判別及びその判別根拠の解明, LED総合フォーラム2021 in 徳島, P-12, Feb. 2021.
9.	Hiroki Tanioka, Takeo Minamikawa, Mayuko Shimizu, 森本友樹, Hiroki Takanari, Ryosuke Shiomi, Eiji Hase, Takeshi Yasui and Koichi Tsuneyama : 非アルコール性脂肪肝炎の蓄積した脂肪に着目したラマン分光イメージング, LED総合フォーラム2021 in 徳島, P-14, Feb. 2021.
10.	Koshirou Hori, Takeo Minamikawa, Yoshiki Terao, Masami Shishibori and Takeshi Yasui : ラマン分光法とSVMを用いた末梢神経の選択的判別における判別根拠の推定, LED総合フォーラム2021 in 徳島, P-13, Feb. 2021.
11.	Keishiroh Ohtani, Takeo Minamikawa, 中野祥太, Eiji Hase and Takeshi Yasui : レーザー走査型光コム分顕微鏡による生体イメージング, LED総合フォーラム2021 in 徳島, P-15, Feb. 2021.
12.	Takeo Minamikawa : 光で見る・視る・診る~可視化の科学~, 夢ナビTALK, Oct. 2019.
13.	Takeo Minamikawa : 顕微分光学への誘い~光で医療を変える~, 夢ナビ講義ライブ, Oct. 2019.
14.	Takeo Minamikawa : 波長分散素子を用いたワンショット共焦点顕微鏡, イノベーション・ジャパン2019 - 大学見本市, Aug. 2019.
15.	Masatomo Yamagiwa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : 位相シフト型テラヘルツ・デジタルホログラフィー, LED総合フォーラム2019 in 徳島, P-17, Feb. 2019.
16.	Kazuki Nitta, JIE CHEN, Tatsuya Mizuguchi, Guoqing Hu, Takeo Minamikawa, 郑铮 and Takeshi Yasui : モード同期多重化ファイバーレーザーとアダプティブ・サンプリングを用いたデュアル・テラヘルツコム分光法, LED総合フォーラム2019 in 徳島, P-18, Feb. 2019.
17.	Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : デュアル光コム分光法におけるロックイン検出の利用, LED総合フォーラム2019 in 徳島, P-19, Feb. 2019.
18.	Hidenori Koresawa, Kyuki Shibuya, 浅原彰文, Takeo Minamikawa, Kaoru Minoshima and Takeshi Yasui : デュアル光コムビートと2次元周波数多重化によるスキャンレス全視野蛍光イメージング, LED総合フォーラム2019 in 徳島, P-20, Feb. 2019.
19.	Takuya Tsuda, Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : フルフィールド共焦点顕微鏡による共焦点位相差イメージング, LED総合フォーラム2019 in 徳島, P-21, Feb. 2019.
20.	Ryosuke Shiomi, Takeo Minamikawa, Ryo Oe and Takeshi Yasui : 擬似ライン照射型ラマン散乱顕微鏡による無染色分子イメージング, LED総合フォーラム2019 in 徳島, P-22, Feb. 2019.
21.	Shota Nakano, Takeo Minamikawa, Eiji Hase, 浅原彰文, Takahiko Mizuno, Hirotsugu Yamamoto and Takeshi Yasui : レーザー走査型光コム顕微鏡の開発, LED総合フォーラム2019 in 徳島, P-23, Feb. 2019.
22.	Yuto Fukuike, Takeo Minamikawa, Shota Nakano, Ryosuke Shiomi, Eiji Hase and Takeshi Yasui : 空間/波長変換を用いたワンショット共焦点顕微鏡の開発と角膜組織診断への応用, LED総合フォーラム2019 in 徳島, P-24, Feb. 2019.
23.	Takeo Minamikawa : 研究費応募に際して若手なりに留意していること, 科研費採択向上のための説明会, Aug. 2018.
24.	Tatsuya Mizuguchi, Takeo Minamikawa and Takeshi Yasui : テラヘルツ波を用いた煙混在ガスのリアルタイム濃度センシング, LED総合フォーラム2016, Dec. 2016.
25.	Takayuki Ogawa, Takeo Minamikawa, Hirotsugu Yamamoto and Takeshi Yasui : テラヘルツ・デジタル・ホログラフィを用いた3次元形状計測, LED総合フォーラム2016, Dec. 2016.

Patent:

1.	Takeshi Yasui, Takeo Minamikawa and Hidenori Koresawa : 表面プラズモン共鳴センサー, 2022-89430 (Jun. 2022), .
2.	Takeshi Yasui and Takeo Minamikawa : ファイバーセンシング装置, 2021-128669 (Aug. 2021), .
3.	Takeshi Yasui, Tetsuo Iwata, Yasuhiro Mizurani, Takeo Minamikawa, Eiji Hase and Hirotsugu Yamamoto : 計測装置及び照射装置, PCT/JP2018/029924 (Aug. 2018), WO2019/031584 (Feb. 2019), US10837906 (Nov. 2021).
4.	Takeo Minamikawa, Eiji Hase, Shuji Miyamoto and Takeshi Yasui : 共焦点顕微鏡及び画像化システム, 2017-188816 (Sep. 2017), 2021-028644 (Feb. 2021), .
5.	Takeshi Yasui, Takeo Minamikawa, Oe Ryo, Taue Shuji, Fukano Hideki and Kaoru Minoshima : 屈折率計測装置及び方法, 2017-160442 (Aug. 2017), 2019-039723 (Mar. 2019), .
6.	Takeshi Yasui, Tetsuo Iwata, Yasuhiro Mizurani, Takeo Minamikawa, Eiji Hase and Hirotsugu Yamamoto : 計測装置及び照射装置, 2017-154392 (Aug. 2017), .
7.	加藤祥行, Takeo Minamikawa, Takeo Minamikawa, 高松哲郎 and 原田義規 : 肿瘤部位的辨別方法，肿瘤部位的辨別装置, 201680064613.9 (Nov. 2016), ZL201680064613.9 (Oct. 2020).
8.	Takeshi Yasui, Tetsuo Iwata, Yasuhiro Mizurani, Takeo Minamikawa, Yi-Da Hsieh, Eiji Hase and Hirotsugu Yamamoto : 計測装置, PCT/JP2016/66636 (Jun. 2016), WO2017/002535 (Jan. 2017), .
9.	Takeo Minamikawa, Yoshinori Harada, Tetsuro Takamatsu and Yoshiyuki Kato : Tumor discrimination method, and tumor discrimination device, 2015-220578 (Nov. 2015), 2017-090250 (May 2017), 6762703 (Sep. 2020).
10.	高松哲郎, 原田義規, Takeo Minamikawa, 大河内健吾 and 加藤祥行 : 肿瘤部位的辨別方法，肿瘤部位的辨別装置, 201580057659.3 (Oct. 2015), ZL201580057659.3 (Jun. 2020).
11.	高松哲郎, 原田義規, Takeo Minamikawa, 三橋博一, 宮川惇紀, 小高大樹, 大河内健吾 and 加藤祥行 : 試祥用夾持器, 201580057436.7 (Oct. 2015), ZL201580057436.7 (Jan. 2019).
12.	高松哲郎, 原田義規, Takeo Minamikawa, 大河内健吾 and 加藤祥行 : 腫瘍部位の判別方法，腫瘍部位の判別装置, 2014-217767 (Oct. 2014), 6635363 (Dec. 2019).
13.	Takeo Minamikawa, Yoshinori Harada, Tetsuro Takamatsu, Yoshiyuki Kato, Hirokazu Mihashi, Junki Miyagawa, Hiroki Kodaka and Kengo Okochi : Holder for sample, 2014-217765 (Oct. 2014), 6443797 (Dec. 2018).
14.	Takeo Minamikawa, Yoshinori Harada, Tetsuro Takamatsu, Yoshiyuki Kato and Kengo Okochi : Tumor discrimination method, and tumor discrimination device, 2014-217768 (Oct. 2014), 6429145 (Nov. 2018).
15.	Takeo Minamikawa, Yoshinori Harada, Tetsuro Takamatsu, Yoshiyuki Kato and Kengo Okochi : Tumor discrimination method, and tumor discrimination device, 2014-217766 (Oct. 2014), .
16.	Takeo Minamikawa, Yoshinori Harada, Tetsuro Takamatsu, Yoshiyuki Kato, Hirokazu Mihashi, Junki Miyagawa, Hiroki Kodaka and Kengo Okochi : Holder for sample, 2014-217689 (Oct. 2014), 2016-85108 (May 2016), 6731216 (Jul. 2020).
17.	Takeo Minamikawa, Yoshinori Harada, Tetsuro Takamatsu, Mitsuo Kawasaki, Koji Takeda, Yu Yamasaki and Masahiro Kawasaki : Examination method, 2013-106649 (May 2013), .
18.	Takeo Minamikawa, Yoshinori Harada, Tetsuro Takamatsu, Mitsuo Kawasaki, Koji Takeda, Yu Yamasaki and Masahiro Kawasaki : Sensor, examination method, 2013-106651 (May 2013), .
19.	Takeo Minamikawa, Yoshinori Harada, Tetsuro Takamatsu, Mitsuo Kawasaki, Koji Takeda, Yu Yamasaki and Masahiro Kawasaki : Examination method, sensor, 2013-106652 (May 2013), .
20.	Takeo Minamikawa, Yoshinori Harada, Tetsuro Takamatsu, Nanae Muranishi, Katsuhiro Ishii, Juichiro Ukon and Junnichi Aoyama : Heart tissue identification method and devise by using Raman scattering, 2012-103435 (May 2013), 2014-224724 (Dec. 2014), 6103700 (Mar. 2017).
21.	Takamatsu Tetsuro, Takeo Minamikawa and Harada Yoshinori : Method for nerve detection by Raman scattering spectroscopy, PCT/JP2013/058775 (Mar. 2013), US9700212 (Jul. 2017).
22.	Tetsuro Takamatsu, Takeo Minamikawa and Yoshinori Harada : ラマン散乱分光法による神経検出法, 2012-79742 (Mar. 2012), WO2013/146779 (Oct. 2015), 6180404 (Jul. 2017).
23.	Takeo Minamikawa, Mamoru Hashimoto, Naoki Tanimoto, Minoru Kobayashi, Katsumasa Fujita, Satoshi Kawata and Tsutomu Araki : Pulse laser light timing adjusting device, adjusting method, and optical microscope, 2006-135293 (May 2006), 4862164 (Nov. 2011).

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

光コムの医光融合研究に立脚した新興・再興ウイルスの超高感度・迅速検出 (Project/Area Number: 22H00303 )
デュアル光磁場コムを用いたメタマテリアル近接場の複素透磁率分光法の開発 (Project/Area Number: 21K18727 )
Environment-resistant molecular sensor by plasmonic Raman spectroscopy without the proximity of metals (Project/Area Number: 21H01847 )
Novel and rapid diagnostic appproach of AL amyloidosis by Raman spectroscopy (Project/Area Number: 20K08712 )
Histological discrimination by Raman spectroscopy based on causal relationship (Project/Area Number: 19K22969 )
Control of dynamics and storage of CO2 in soft porous solids (Project/Area Number: 19K22233 )
Dual-comb microscopy~Will optical frequency combs bring innovative advances to confocal microscopy?~ (Project/Area Number: 19H00871 )
Noninvasive biomedical imaging using optical-comb microscopy (Project/Area Number: 18H01901 )
Development of autofluorescence-free Raman spectroscopy and its applications to biomedical imaging (Project/Area Number: 16K16389 )
Development of a light enhancement plate for Raman spectroscopy (Project/Area Number: 15K12519 )
One-shot dual-comb 3D microscopy and spectroscopic imaging to evaluate moisture content of a living plant (Project/Area Number: 15H02026 )
Detection of malignant tumor by using nonlinear Raman spectroscopy (Project/Area Number: 25560206 )
Visualization of peripheral nerves for nerve-sparing surgery (Project/Area Number: 24300165 )
Search by Researcher Number (10637193)

Associate Professor, Associate Professor, Designated Associate Professor : Minamikawa, Takeo

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