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Tokushima UniversityGraduate School of Biomedical Sciences歯学域Oral ScienceBasic DentistryDepartment of Oral and Maxillofacial Anatomy
Tokushima UniversityFaculty of DentistryCourse in DentistryBasic Oral SciencesOral and Maxillofacial Anatomy
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Research Activity

Field of Study

Oral Anatomy
Oral Anatomy
Cell Physiology

Subject of Study

Dentin Formation (dentin, dentin protein, odontoblast, dental pulp)
Formation/Regeneration of Periodontium (alveolar bone, periodontal ligament, cementum, osteoblast, dentin proein)
metabolism of glycogen (glycogen, antibody, immunohistochemisry)

Book / Paper

Book:

1. Otto Baba :
口腔解剖学 第2版,
Ishiyaku Publishers,Inc., Tokyo, Feb. 2018.

Academic Paper (Judged Full Paper):

1. Tsuyoshi Kano, Tsuyoshi Morita, Kaori Sumida, Hiromichi Yumoto and Otto Baba :
Expression of fibroblast growth factor receptor1, -2c, and -3c transcripts in mouse molars after tooth eruption,
Anatomical Science International, 2021.
(DOI: 10.1007/s12565-020-00594-4,   Elsevier: Scopus)
2. Resmi Raju, Masamitsu Ohshima, Miho Inoue, Tsuyoshi Morita, Yan Huijiao, Arief Waskitho, Otto Baba, Masahisa Inoue and Yoshizo Matsuka :
Three-dimensional periodontal tissue regeneration using a bone-ligament complex cell sheet,
Scientific Reports, Vol.10, No.1, 1656, 2020.
(Tokushima University Institutional Repository: 114213,   DOI: 10.1038/s41598-020-58222-0,   PubMed: 32015383)
3. Takuma Iwasa, S Afroz, Miho Inoue, Rieko Arakaki, Masamitsu Ohshima, R Raju, Arief Waskitho, Inoue Masahisa, Otto Baba and Yoshizo Matsuka :
IL-10 and CXCL2 in trigeminal ganglia in neuropathic pain,
Neuroscience Letters, Vol.703, 132-138, 2019.
(Tokushima University Institutional Repository: 113686,   DOI: 10.1016/j.neulet.2019.03.031)
4. Elizabeth Haythorne, Maria Rohm, Martijn de Bunt van, F Melissa Brereton, I Andrei Tarasov, S Thomas Blacker, Gregor Sachse, Mariana Dos Santos Silva, Raul Exposito Terron, Simon Davis, Otto Baba, Roman Fischer, R Michael Duchen, Patrik Rorsman, I James MacRae and M Frances Ashcroft :
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells.,
Nature Communications, Vol.10, No.1, 2019.
(Tokushima University Institutional Repository: 115227,   DOI: 10.1038/s41467-019-10189-x,   PubMed: 31171772)
5. S Afroz, Rieko Arakaki, Takuma Iwasa, Masamitsu Ohshima, Maki Hosoki, Miho Inoue, Otto Baba, Yoshihiro Okayama and Yoshizo Matsuka :
CGRP induces differential regulation of cytokines from satellite glial cells in trigeminal ganglia and orofacial nociception,
International Journal of Molecular Sciences, Vol.20, No.3, 711-730, 2019.
(Tokushima University Institutional Repository: 113687,   DOI: 10.3390/ijms20030711,   PubMed: 30736422,   Elsevier: Scopus)
6. Furukawa Fumiya, Irachi Shotaro, Koyama Mugen, Otto Baba, Akimoto Hajime, Okumura Sei-ichi, Kagawa Hirohiko and Uchida Katsuhisa :
Changes in glycogen concentration and gene expression levels of glycogen-metabolizing enzymes in muscle and liver of developing masu salmon.,
Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology, Vol.225, 72-84, 2018.
(DOI: 10.1016/j.cbpa.2018.07.003,   PubMed: 30017911)
7. Kaori Sumida, Yoshinori Ando, Shinichiro Seki, Kikuji Yamashita, Akira Fujimura, Otto Baba and Seiichiro Kitamura :
Anatomical status of the human palatopharyngeal sphincter and its functional implications.,
Surgical and Radiologic Anatomy : SRA, Vol.39, No.11, 1191-1201, 2017.
(DOI: 10.1007/s00276-017-1855-6,   PubMed: 28447150)
8. Shinichiro Seki, Kaori Sumida, Kikuji Yamashita, Otto Baba and Seiichiro Kitamura :
Gross anatomical classification of the courses of the human lingual artery.,
Surgical and Radiologic Anatomy : SRA, Vol.39, No.2, 195-203, 2017.
(DOI: 10.1007/s00276-016-1696-8,   PubMed: 27189234,   Elsevier: Scopus)
9. Kikuji Yamashita, Dalkhsuren Shine-Od, Aldartsogt Dolgorsuren, Kaori Sumida, Tsuyoshi Morita and Otto Baba :
Effects of Dietary Cure Containing AFIR (Antioxidant Far-Infrared Energy Radiating) Ceramics on Living Body of Hatchery Sea Bream (Pagrus Major),
International Journal of Innovative Studies in Sciences and Engineering Technology, Vol.2, No.10, 7-16, 2016.
10. Tsuyoshi Morita, Kaoru Fujikawa, Otto Baba and Shibata Shunichi :
An in situ hybridization study of Hyaluronan synthase (Has) mRNA in developing mouse molar and incisor tooth germs,
Gene Expression Patterns, Vol.21, No.1, 28-40, 2016.
(DOI: 10.1016/j.gep.2016.06.002,   PubMed: 27289075)
11. Otto Baba :
Production of monoclonal antibody that recognizes glycogen and its application for immunohistochemistry,
The Journal of the Stomatological Society, Japan, Vol.60, No.2, 264-287, 1993.

Review, Commentary:

1. Otto Baba :
知れば安心,もっと楽しい! 解剖学的口腔の観かた∼下顎骨を知る 第6回下顎骨の成長・歯の喪失による形態変化,
The Journal of Dental Hygiene, Vol.40, No.4, 346-350, Mar. 2020.
2. Otto Baba :
知れば安心,もっと楽しい! 解剖学的口腔の観かた∼下顎骨を知る 第5回下顎骨に付着する筋肉と咀嚼・嚥下運動,
The Journal of Dental Hygiene, Vol.40, No.3, 236-239, Feb. 2020.
3. Otto Baba :
知れば安心,もっと楽しい! 解剖学的口腔の観かた∼下顎骨を知る 第4回口腔壁を構成する下顎に付着する筋,
The Journal of Dental Hygiene, Vol.40, No.2, 122-125, Jan. 2020.
4. Otto Baba :
知れば安心,もっと楽しい! 解剖学的口腔の観かた∼下顎骨を知る 第3回下顎骨の基本構造③(下顎孔と下顎管と関節突起について),
The Journal of Dental Hygiene, Vol.40, No.1, 12-15, Dec. 2019.
5. Otto Baba :
知れば安心,もっと楽しい! 解剖学的口腔の観かた∼下顎骨を知る 第2回 下顎骨の基本構造②(下顎枝について),
The Journal of Dental Hygiene, Vol.39, No.12, 1240-1242, Nov. 2019.
6. Otto Baba :
知れば安心,もっと楽しい! 解剖学的口腔の観かた∼下顎骨を知る 第1回 下顎骨の基本構造①(概要と下顎体について),
The Journal of Dental Hygiene, Vol.39, No.11, 1127-1129, Oct. 2019.
7. Otto Baba :
The New Insight into Radicular Dentin Formation,
Journal of Oral Health and Biosciences, Vol.29, No.1, 1-6, Jun. 2016.
(Tokushima University Institutional Repository: 109874,   CiNii: 120005823529)

Proceeding of International Conference:

1. S Afroz, Rieko Arakaki, Takuma Iwasa, Masamitsu Ohshima, Maki Hosoki, Miho Inoue, Otto Baba, Yoshihiro Okayama and Yoshizo Matsuka :
CGRP induced glial-cytokine expression, NFkB signaling and orofacial nociception,
International Association for Dental Research, Washington, D.C., Mar. 2020.
2. Otto Baba :
Regulation of Odontoblasts in Various Phases of Dentin Formation,
DENTISPHERE 4 (International Scientific Meeting 5th Asean Plus & Tokushima Joint International Conference), Surabaya, Indonesia, Nov. 2019.
3. R Raju, Masamitsu Ohshima, Tsuyoshi Morita, Huijiao Yan, Miho Inoue, Otto Baba, Masahisa Inoue and Yoshizo Matsuka :
A double-layered complex cell sheet can regenerate the periodontal tissue in a mice model,
Dentisphere, Surabayai, Nov. 2019.
4. S Afroz, Rieko Arakaki, Takuma Iwasa, Masamitsu Ohshima, Otto Baba, Y Okayama and Yoshizo Matsuka :
Orofacial pain due to glial expressed cytokines in trigeminal ganglion,
Dentisphere, Surabayai, Nov. 2019.
5. Arief Waskitho, Yumiko Yamamoto, Tsuyoshi Morita, Huijiao Yan, R Raju, Masamitsu Ohshima, Junhel Dalanon, Otto Baba and Yoshizo Matsuka :
Bilateral effects of unilateral administration of botulinum toxin A in chemotherapy induced neuropathy,
Dentisphere, Surabayai, Nov. 2019.
6. Otto Baba :
Symposium: Perspectives on the Impact of William Butler's Mentoring,
97th General session & exhibition of the IADR, Vancouver, Jun. 2019.
7. S Afroz, Rieko Arakaki, Takuma Iwasa, Masamitsu Ohshima, Maki Hosoki, Miho Inoue, Otto Baba, Yoshihiro Okayama and Yoshizo Matsuka :
Orofacial nociception due to glial expressed cytokines in trigeminal ganglia,
International Association for Dental Research, Vancouver, Jun. 2019.
8. Kazumitsu Sekine, Yoshihito Naitou, Tetsuo Ichikawa, Otto Baba and Kenichi Hamada :
Development of structural and chemical enforcement of neointimal growth as the blood contacting surface for the vascular prosthesis,
45th European Society for Artificial Organs 2018 Congress, Madrid, Sep. 2018.
9. Y Kumei, J Zeredo, R Watahiki, K Kagiyama, K Fukasawa and Otto Baba :
Common marmosets in Martian, Lunar, and zero gravity conditions: posture, behavior and motion sickness.,
The Joint Conference of the 7th International Symposium on Physical Sciences in Space & 25th European Low Gravity Research Association Biennial Symposium and General Assembly, Oct. 2017.
10. R Watahiki, J Zeredo, K Kagiyama, H Hashimoto, N Ishioka, Y Inatomi, Otto Baba, S Aou, K Natsume and Y Kumei :
Postural and behavioral of primates (Common Marmoset) to Martian, Lunar, and Zero gravity conditions.,
American Society for Gravitational and Space Research Annual Meeting, Oct. 2016.

Proceeding of Domestic Conference:

1. Kaori Sumida, Seiichiro Kitamura, Tsuyoshi Morita, 神尾 強司, 城 翠, 古田 琴, 濱 義之, 田畑 純 and Otto Baba :
コモンリスザルの軟口蓋・咽頭の筋構築に関する肉眼解剖学的研究,
第125回日本解剖学会総会・全国学術集会 講演プログラム・抄録集 山口 2020 誌上開催, 162, Mar. 2020.
2. Yui Miyagawa, Masaki Gotoh, Yukari Hatada, Tsuyoshi Morita, Tsuyoshi Kano, Kaori Sumida and Otto Baba :
マダイ稚魚の歯の形成過程に関する組織学的研究,
The 125th Annual Meeting of The Japanese Association of Anatomists, Mar. 2020.
3. Tsuyoshi Morita, Tsuyoshi Kano, Kaori Sumida and Otto Baba :
歯・歯周組織の形成機構の解析および再生への応用の検討,
四国歯学会第56回例会, Feb. 2020.
4. Shin Matsumoto, Soichiroh Kinjoh, Tsuyoshi Morita, Kaori Sumida, Tsuyoshi Kano and Otto Baba :
メダカ咽頭歯における歯および歯周組織の形成遺伝子の発現,
四国歯学会第56回例会, 34, Feb. 2020.
5. Takuma Iwasa, Afroz Shaista, Miho Inoue, Rieko Arakaki, Masamitsu Ohshima, Raju Resmi, Arief Waskitho, 井上 正久, Otto Baba and Yoshizo Matsuka :
痛みに対するサイトカイン療法の開発に向けて,
徳島県歯科医学大会, Feb. 2020.
6. Tsuyoshi Kano, Tsuyoshi Morita, Kaori Sumida, Hiromichi Yumoto and Otto Baba :
Gene expression of dentin formation related factors in dental pulp of mouse molar, after tooth eruption,
第61回歯科基礎医学会学術大会, Oct. 2019.
7. Waskitho Arief, Yamamoto Yumiko, Tsuyoshi Morita, Yan Huijiao, Raju Resmi, Masamitsu Ohshima, Dalanon Junhel, Otto Baba and Yoshizo Matsuka :
Orofacial neuropathic pain rat models induced by chemotherapy drugs,
Tokushima University Bioscience Retreat, Sep. 2019.
8. Raju Resmi, Masamitsu Ohshima, Miho Inoue, Tsuyoshi Morita, Yan Huijiao, Otto Baba, Inoue Masahisa and Yoshizo Matsuka :
Development of a multilayered complex cell sheet to regenerate periodontal tissue,
Tokushima University Bioscience Retreat, Sep. 2019.
9. Raju Resmi, Masamitsu Ohshima, Miho Inoue, Tsuyoshi Morita, Yan Huijiao, Otto Baba, 井上 正久 and Yoshizo Matsuka :
骨芽細胞と歯根膜細胞との立体形成複合細胞シートによる歯周組織再生の確立,
硬組織再生生物学会, Aug. 2019.
10. Kazumitsu Sekine, Otto Baba and Kenichi Hamada :
細胞賦活化処理による多孔質性状チタン足場材の生体内癒合性の向上を狙う,
第58回日本生体医工学会大会, Jun. 2019.
11. Kaori Sumida, Seiichiro Kitamura, Tsuyoshi Morita, 神尾 強司, 田畑 純 and Otto Baba :
ヒト,ウマ,イヌの茎突咽頭筋の走行・停止の比較からヒト茎突咽頭筋の機能を考える,
第124回日本解剖学会総会全国学術集会, Mar. 2019.
12. Shin Matsumoto, Soichiroh Kinjoh, Sohshi Fujita, Tsuyoshi Morita, Tsuyoshi Kano, Kaori Sumida, Asuna Sugimoto, Tsutomu Iwamoto and Otto Baba :
メダカ咽頭歯における分泌性カルシウム結合リンタンパク質(SCPP)遺伝子の発現,
第124回日本解剖学会総会・全国学術集会, Mar. 2019.
13. Kazumitsu Sekine, Otto Baba and Kenichi Hamada :
細胞賦活性を施した多孔質チタン足場材に関する生体内癒合性評価,
第56回日本人工臓器学会大会, Nov. 2018.
14. 金城 聡一郎, Shin Matsumoto, 藤田 創詩, Kaori Sumida, Tsuyoshi Morita, 神尾 強司 and Otto Baba :
馬蹄腎の一例についての肉眼解剖学的および組織学的観察,
四国歯学会第53回例会・第37回総会, Jul. 2018.
15. Kazumitsu Sekine, Otto Baba and Kenichi Hamada :
Evaluation of Titanium surface modification for hard tissue prostheses,
第57回日本生体医工学会大会, Jun. 2018.
16. Kaori Sumida, Seiichiro Kitamura, 神尾 強司, Tsuyoshi Morita, Kikuji Yamashita and Otto Baba :
イヌの軟口蓋の筋構築に関する肉眼解剖学的研究,
日本解剖学会総会・第123回全国学術集会,, Mar. 2018.
17. Kaori Sumida, Seiichiro Kitamura, Tsuyoshi Morita, Kikuji Yamashita and Otto Baba :
Gross anatomical study of the human stylopharyngeus: origin, course,and insertion.,
The 122nd annual meeting of the Japanese association of anatomists, Mar. 2017.

Et cetera, Workshop:

1. Raju Resmi, Masamitsu Ohshima, Tsuyoshi Morita, Yan Huijiao, Miho Inoue, Otto Baba, Inoue Masahisa and Yoshizo Matsuka :
Three-dimensional periodontal tissue regeneration using a bone-ligament complex cell sheet,
発生・再生・遺伝クラスター ミニリトリート, Feb. 2020.
2. Waskitho Arief, Yumiko Yamamoto, Tsuyoshi Morita, Yan Huijiao, Raju Resmi, Masamitsu Ohshima, Dalanon Junhel, Laksmi Swarna, Chavan P., Otto Baba and Yoshizo Matsuka :
Botulinum toxin A administration in chemotherapy-induced neuropathic pain rat model,
徳島大学脳科学クラスターミニリトリート, Feb. 2020.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • Common marmoset as a primate model for gerontology in dentistry (Project/Area Number: 16K15852 )
  • The common marmoset, a new-world monkey as a human-alternative model for studies on pediatric dentistry (Project/Area Number: 26463107 )
  • New paradigm of enamel maturation: Mechanisms of non-endocytotic resorption and degradation of enamel matrix proteins (Project/Area Number: 24390408 )
  • The study on the cells forming periodontium by observing the expression of dentin proteins as the markers of differentiation (Project/Area Number: 18591996 )
  • Establishment of organ culture system for tooth regeneration using pharyngeal teeth of medaka and its use for the exploration of dental stem cells (Project/Area Number: 18390485 )
  • The induction of periodontal tissues by dentin-derived matrix (Project/Area Number: 14370577 )
  • Structural analysis of the role of enamel matrix proteins in regeneration of biological hard tissues (Project/Area Number: 12557151 )
  • 骨、軟骨組織に加齢および外力が与える影響とその機構に関する解析 (Project/Area Number: 08771560 )
  • Biochemical and histological analysis of proteoglycans systhsized by cartilaginous cell line, ATDC5. (Project/Area Number: 07671963 )
  • Immunohistochemical and Enzyme-histochemical studies on the cellular networks of antigen-presenting cells in the dental and periodontal tissues. (Project/Area Number: 07457426 )
  • 下顎頭軟骨に対するモノクローナル抗体の作製と免疫組織化学的観察 (Project/Area Number: 06771574 )
  • 石灰化に伴う各種プロテオグリカンの構造変化に関する生化学的、組織化学的解析 (Project/Area Number: 06671806 )
  • Search by Researcher Number (90251545)