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Tokushima UniversityGraduate School of Biomedical Sciences歯学域Oral ScienceBasic DentistryDepartment of Oral Molecular Pathology
Tokushima UniversityFaculty of DentistryCourse in DentistryBasic Oral SciencesOral Molecular Pathology
Tokushima UniversityResearch ClustersResearch Clusters2202002 独自の解析技術と疾患科学の融合によるリボソーム創薬の創生
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Research

Field of Study

Subject of Study

Book / Paper

Book:

1. Kunihiro Otsuka, Takaaki Tsunematsu and Naozumi Ishimaru :
シェーグレン症候群の病理診断,
日本病理学会,
2. Takaaki Tsunematsu, 俵 宏彰, Kunihiro Otsuka, Aya Ushio and Naozumi Ishimaru :
ヒトパピローマウイルス陽性がんにおける脱ユビキチン化酵素の役割,
日本口腔組織培養学会, Nov. 2022.
3. Kunihiro Otsuka, Takaaki Tsunematsu, Aya Ushio, Mami Sato and Naozumi Ishimaru :
シェーグレン症候群の病理,
Oct. 2022.

Academic Paper (Judged Full Paper):

1. Shengjian Jin, Takaaki Tsunematsu, Taigo Horiguchi, Yasuhiro Mouri, Wenhua Shao, Keiko Miyoshi, Hiroko Hagita, Motoharu Sarubo, Natsumi Fujiwara, Qi Guangying, Naozumi Ishimaru and Yasusei Kudo :
Involvement of the OTUB1-YAP1 axis in driving malignant behaviors of head and neck squamous cell carcinoma.,
Cancer Medicine, 2023.
(Tokushima University Institutional Repository: 118778,   DOI: 10.1002/cam4.6735,   PubMed: 37986681)
2. 富田 満, Hirohisa Ogawa, Takaaki Tsunematsu, Mami Sato, 山下 貴央, Yoshiaki Kitamura, Naozumi Ishimaru, Koichi Tsuneyama, Hisanori Uehara and Yoshimi Bando :
線維化と腫瘍随伴リンパ組織増生を伴う粘表皮癌の1例,
診断病理, Vol.40, No.4, 336-341, 2023.
3. Mami Sato-Fukuba, Rieko Arakaki, Aya Ushio, Kunihiro Otsuka, Ruka Nagao, Shigefumi Matsuzawa, Hiroaki Tawara, Takaaki Tsunematsu and Naozumi Ishimaru :
CD4 T-cell-dependent differentiation of CD23 follicular B cells contributes to the pulmonary pathology in a primary Sjögren's syndrome mouse model.,
Frontiers in Immunology, Vol.14, 1217492, 2023.
(Tokushima University Institutional Repository: 118467,   DOI: 10.3389/fimmu.2023.1217492,   PubMed: 37475871,   Elsevier: Scopus)
4. Wenhua Shao, Takaaki Tsunematsu, Masaaki Umeda, Hiroaki Tawara, Natsumi Fujiwara, Yasuhiro Mouri, Rieko Arakaki, Naozumi Ishimaru and Yasusei Kudo :
Cancer cell-derived novel periostin isoform promotes invasion in head and neck squamous cell carcinoma.,
Cancer Medicine, 2023.
(Tokushima University Institutional Repository: 118312,   DOI: 10.1002/cam4.5601,   PubMed: 36691359)
5. Mami Sato, Rieko Arakaki, Hiroaki Tawara, Ruka Nagao, Hidetaka Tanaka, Kai Tamura, Yuki Kawahito, Aya Ushio, Takaaki Tsunematsu and Naozumi Ishimaru :
Disturbed natural killer cell homeostasis in the salivary gland enhances autoimmune pathology via IFN-γ in a mouse model of primary Sjogren's syndrome.,
Frontiers in Medicine, Vol.9, 1036787, 2022.
(Tokushima University Institutional Repository: 118305,   DOI: 10.3389/fmed.2022.1036787,   PubMed: 36388880)
6. Takaaki Tsunematsu, Rieko Arakaki, Mami Sato, Masako Saito, Kunihiro Otsuka, Furukawa Yusuke, Taquahashi Yuhji, Kanno Jun and Naozumi Ishimaru :
Exposure to Multiwall Carbon Nanotubes Promotes Fibrous Proliferation by Production of Matrix Metalloproteinase-12 via NF-κB Activation in Chronic Peritonitis.,
The American Journal of Pathology, Vol.S0002-9440, No.22, 00240, 2022.
(DOI: 10.1016/j.ajpath.2022.07.009,   PubMed: 35963465)
7. Kunihiro Otsuka, Mami Sato, Takaaki Tsunematsu and Naozumi Ishimaru :
Virus Infections Play Crucial Roles in the Pathogenesis of Sjögren's Syndrome.,
Viruses, Vol.14, No.7, 1474, 2022.
(Tokushima University Institutional Repository: 117727,   DOI: 10.3390/v14071474,   PubMed: 35891453,   Elsevier: Scopus)
8. Mayuko Shimizu, Soichiroh Ishimaru, Wai Yee Yan Christine, Takeo Minamikawa, Takaaki Tsunematsu, Aiko Endoh, Takumi Kojima, Minoru Matsumoto, Tomoko Kobayashi, Satoshi Sumida, Takumi Kakimoto, MIYAGAMI Yuko, Hirohisa Ogawa, Takeshi Oya and Koichi Tsuneyama :
Establishment of an epicutaneously sensitized murine model of shellfish allergy and evaluation of skin condition by Raman microscopy.,
Applied Sciences, Vol.12, No.3566, 2022.
(Tokushima University Institutional Repository: 117211,   DOI: 10.3390/app12073566)
9. Shu Chen, Naofumi Tamaki, Yasusei Kudo, Takaaki Tsunematsu, Kaname Miki, Naozumi Ishimaru and Hiro-O Ito :
Protective effects of resveratrol against 5-fluorouracil-induced oxidative stress and inflammatory responses in human keratinocytes.,
Journal of Clinical Biochemistry and Nutrition, Vol.69, No.3, 238-246, 2021.
(Tokushima University Institutional Repository: 116380,   DOI: 10.3164/jcbn.21-23,   PubMed: 34857985)
10. Mami Sato, Rieko Arakaki, Hiroaki Tawara, Takaaki Tsunematsu and Naozumi Ishimaru :
Formation of Autoimmune Lesions Is Independent of Antibiotic Treatment in NOD Mice.,
International Journal of Molecular Sciences, Vol.22, No.6, 3239, 2021.
(Tokushima University Institutional Repository: 117463,   DOI: 10.3390/ijms22063239,   PubMed: 33810172)
11. Takaaki Tsunematsu, Rieko Arakaki, Hidehiko Kawai, Jan Ruppert, Koichi Tsuneyama, Naozumi Ishimaru, C William Earnshaw, Michele Pagano and Yasusei Kudo :
is required for the termination of chromosomal passenger complex activity upon mitotic exit.,
Journal of Cell Science, Vol.133, No.18, 2020.
(Tokushima University Institutional Repository: 115422,   DOI: 10.1242/jcs.251314,   PubMed: 32934012,   Elsevier: Scopus)
12. Satoru Kisoda, Wenhua Shao, Natsumi Fujiwara, Yasuhiro Mouri, Takaaki Tsunematsu, Shengjian Jin, Rieko Arakaki, Naozumi Ishimaru and Yasusei Kudo :
Prognostic value of partial EMT-related genes in head and neck squamous cell carcinoma by a bioinformatic analysis.,
Oral Diseases, Vol.26, No.6, 1149-1156, 2020.
(Tokushima University Institutional Repository: 114969,   DOI: 10.1111/odi.13351,   PubMed: 32277532,   Elsevier: Scopus)
13. Kunihiro Otsuka, Akiko Yamada, Masako Saito, Aya Ushio, Mami Sato, Satoru Kisoda, Wenhua Shao, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
Ascl2-Regulated Follicular Helper T Cells Promote Autoimmunity in a Murine Model for Sjögren's Syndrome.,
The American Journal of Pathology, Vol.189, No.12, 2414-2427, 2019.
(DOI: 10.1016/j.ajpath.2019.08.008,   PubMed: 31539517,   Elsevier: Scopus)
14. Aya Ushio, Rieko Arakaki, Kunihiro Ohtsuka, Akiko Yamada, Takaaki Tsunematsu, Yasusei Kudo, Keiko Aota, Masayuki Azuma and Naozumi Ishimaru :
CCL22-Producing Resident Macrophages Enhance T Cell Response in Sjögren's Syndrome.,
Frontiers in Immunology, Vol.9, 2594, 2018.
(Tokushima University Institutional Repository: 113526,   DOI: 10.3389/fimmu.2018.02594,   PubMed: 30467506,   Elsevier: Scopus)
15. Kazuchika Nishitsuji, Syunsuke Watanabe, Jinzhong Xiao, Ryosuke Nagatomo, Hirohisa Ogawa, Takaaki Tsunematsu, Hitomi Umemoto, Yuki Morimoto, Hiroyasu Akatsu, Koichi Inoue and Koichi Tsuneyama :
Effect of coffee or coffee components on gut microbiome and short-chain fatty acids in a mouse model of metabolic syndrome.,
Scientific Reports, Vol.8, No.1, 2018.
(Tokushima University Institutional Repository: 114533,   DOI: 10.1038/s41598-018-34571-9,   PubMed: 30385796)
16. Kunihiro Ohtsuka, Kohichi Yamada, Yuhji Taquahashi, Rieko Arakaki, Aya Ushio, Masako Saito, Akiko Yamada, Takaaki Tsunematsu, Yasusei Kudo, Jun Kanno and Naozumi Ishimaru :
Long-term polarization of alveolar macrophages to a profibrotic phenotype after inhalation exposure to multi-wall carbon nanotubes.,
PLoS ONE, Vol.13, No.10, e0205702., 2018.
(Tokushima University Institutional Repository: 113371,   DOI: 10.1371/journal.pone.0205702,   PubMed: 30372450,   Elsevier: Scopus)
17. Hirohisa Ogawa, Masahiko Azuma, Takaaki Tsunematsu, Yuuki Morimoto, Mayo Kondo, Toshifumi Tezuka, Yasuhiko Nishioka and Koichi Tsuneyama :
Neutrophils induce smooth muscle hyperplasia via neutrophil elastase-induced FGF-2 in a mouse model of asthma with mixed inflammation.,
Clinical and Experimental Allergy, Vol.48, No.12, 1715-1725, 2018.
(DOI: 10.1111/cea.13263,   PubMed: 30171733)
18. Penkhae Utaijaratrasmi, Kulthida Vaeteewoottacharn, Takaaki Tsunematsu, Pranisa Jamjantra, Sopit Wongkham, Chawalit Pairojkul, Narong Khuntikeo, Naozumi Ishimaru, Yongyut Sirivatanauksorn, Ananya Pongpaibul, Peti Thuwajit, Chanitra Thuwajit and Yasusei Kudo :
The microRNA-15a-PAI-2 axis in cholangiocarcinoma-associated fibroblasts promotes migration of cancer cells.,
Molecular Cancer, Vol.17, No.1, 2018.
(Tokushima University Institutional Repository: 113571,   DOI: 10.1186/s12943-018-0760-x,   PubMed: 29347950)
19. Mie Kurosawa, Rieko Arakaki, Akiko Yamada, Takaaki Tsunematsu, Yasusei Kudo, J Sprent and Naozumi Ishimaru :
NF κB2 Controls the Migratory Activity of Memory T Cells by Regulating Expression of CXCR4 in a Mouse Model of Sjögren's Syndrome,
Arthritis & Rheumatology, Vol.69, No.11, 2193-2202, 2017.
(Tokushima University Institutional Repository: 111719,   DOI: 10.1002/art.40230,   PubMed: 28804991,   Elsevier: Scopus)
20. Koichi Tsuneyama, Kazuchika Nishitsuji, Minoru Matsumoto, Tomoko Kobayashi, Yuki Morimoto, Takaaki Tsunematsu and Hirohisa Ogawa :
Animal models for analyzing metabolic syndrome-associated liver diseases.,
Pathology International, Vol.67, No.11, 539-546, 2017.
(DOI: 10.1111/pin.12600,   PubMed: 29027308)
21. Hidesuke Tada, Natsumi Fujiwara, Takaaki Tsunematsu, Yoshiko Tada, Rieko Arakaki, Naofumi Tamaki, Naozumi Ishimaru and Yasusei Kudo :
Preventive effects of mouthguard use while sleeping on recurrent aphthous stomatitis: Preliminary interventional study.,
Clinical and Experimental Dental Research, Vol.3, No.5, 198-203, 2017.
(Tokushima University Institutional Repository: 111727,   DOI: 10.1002/cre2.88,   PubMed: 29744201)
22. Satoko Kujiraoka, Takaaki Tsunematsu, Yukiko Sato, Maki Yoshida, Ayataka Ishikawa, Rei Tohyama, Michio Tanaka, Yutaka Kobayashi, Tomoyuki Kondo, Aya Ushio, Kunihiro Otsuka, Mie Kurosawa, Masako Saito, Akiko Yamada, Rieko Arakaki, Hirokazu Nagai, Hiromasa Nikai, Kengo Takeuchi, Toshitaka Nagao, Youji Miyamoto, Naozumi Ishimaru and Yasusei Kudo :
Establishment and characterization of a clear cell odontogenic carcinoma cell line with EWSR1-ATF1 fusion gene.,
Oral Oncology, Vol.69, 46-55, 2017.
(Tokushima University Institutional Repository: 111726,   DOI: 10.1016/j.oraloncology.2017.04.003,   PubMed: 28559020)
23. Syunsuke Watanabe, Tetsuyuki Takahashi, Hirohisa Ogawa, Hisanori Uehara, Takaaki Tsunematsu, Hayato Baba, Yuki Morimoto and Koichi Tsuneyama :
Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome, Tsumura-Suzuki Obese Diabetic Mice.,
Metabolic Syndrome and Related Disorders, Vol.15, No.4, 170-177, 2017.
(Tokushima University Institutional Repository: 113349,   DOI: 10.1089/met.2016.0114,   PubMed: 28358620)
24. Toshinori Ando, Yasusei Kudo, Shinji Iizuka, Takaaki Tsunematsu, Hanako Umehara, Madhu Shrestha, Toshihiro Matsuo, Tadahiko Kubo, Shouji Shimose, Koji Arihiro, Ikuko Ogawa, Mitsuo Ochi and Takashi Takata :
Ameloblastin induces tumor suppressive phenotype and enhances chemosensitivity to doxorubicin via Src-Stat3 inactivation in osteosarcoma.,
Scientific Reports, Vol.7, 40187, 2017.
(Tokushima University Institutional Repository: 112332,   DOI: 10.1038/srep40187,   PubMed: 28054649,   Elsevier: Scopus)
25. Koichi Tsuneyama, Hayato Baba, Yuki Morimoto, Takaaki Tsunematsu and Hirohisa Ogawa :
Primary Biliary Cholangitis: Its Pathological Characteristics and Immunopathological Mechanisms.,
The Journal of Medical Investigation : JMI, Vol.64, No.1.2, 7-13, 2017.
(Tokushima University Institutional Repository: 111056,   DOI: 10.2152/jmi.64.7,   PubMed: 28373632)
26. Takashi Izawa, Rieko Arakaki, Hiroki Mori, Takaaki Tsunematsu, Yasusei Kudo, Eiji Tanaka and Naozumi Ishimaru :
The nuclear receptor AhR controls bone homeostasis by regulating osteoclast differentiation via the RANK/c-Fos signaling axis.,
The Journal of Immunology, Vol.197, No.12, 4639-4650, 2016.
(DOI: 10.4049/jimmunol.1600822,   PubMed: 27849171)
27. Takaaki Tsunematsu, Natsumi Fujiwara, Maki Yoshida, Yukihiro Takayama, Satoko Kujiraoka, Guangying Qi, Masae Kitagawa, Tomoyuki Kondo, Akiko Yamada, Rieko Arakaki, Mutsumi Miyauchi, Ikuko Ogawa, Yoshihiro Abiko, Hiroki Nikawa, Shinya Murakami, Takashi Takata, Naozumi Ishimaru and Yasusei Kudo :
Human odontogenic epithelial cells derived from epithelial rests of Malassez possess stem cell properties.,
Laboratory Investigation; a Journal of Technical Methods and Pathology, 2016.
(Tokushima University Institutional Repository: 113576,   DOI: 10.1038/labinvest.2016.85,   PubMed: 27479086)
28. Mariko Obayashi, Maki Yoshida, Takaaki Tsunematsu, Ikuko Ogawa, Tomonori Sasahira, Hiroki Kuniyasu, Issei Imoto, Yoshimitsu Abiko, Dan Xu, Saori Fukunaga, Hidetoshi Tahara, Yasusei Kudo, Toshitaka Nagao and Takashi Takata :
microRNA-203 suppresses invasion and epithelial-mesenchymal transition induction via targeting NUAK1 in head and neck cancer.,
Oncotarget, Vol.7, No.7, 8223-8239, 2016.
(Tokushima University Institutional Repository: 113044,   DOI: 10.18632/oncotarget.6972,   PubMed: 26882562,   Elsevier: Scopus)
29. Akiko Yamada, Aya Ushio, Rieko Arakaki, Takaaki Tsunematsu, Yasusei Kudo, Yoshio Hayashi and Naozumi Ishimaru :
Impaired expansion of regulatory T cells in a neonatal thymectomy-induced autoimmune mouse model.,
The American Journal of Pathology, Vol.185, No.11, 2886-2897, 2015.
(Tokushima University Institutional Repository: 113529,   DOI: 10.1016/j.ajpath.2015.07.007,   PubMed: 26343329)
30. Takaaki Tsunematsu, Rieko Arakaki, Akiko Yamada, Naozumi Ishimaru and Yasusei Kudo :
The non-canonical role of Aurora-A in DNA replication.,
Frontiers in Oncology, Vol.96, No.4, 468-480, 2015.
(Tokushima University Institutional Repository: 110980,   DOI: 10.3389/fonc.2015.00187,   PubMed: 26380219)

Academic Paper (Unrefereed Paper):

1. Daishiroh Kobayashi, Masaya Denda, JUNYA Hayashi, Kohta Hidaka, Yutaka Kohmura, Takaaki Tsunematsu, Kohei Nishino, Harunori Yoshikawa, OHKAWACHI Kento, Kiyomi Nigorikawa, Tetsuro Yoshimaru, Naozumi Ishimaru, Nomura Wataru, Toyomasa Katagiri, Hidetaka Kosako and Akira Otaka :
Sulfoxide-mediated Cys-Trp-selective bioconjugation that enables protein labeling and peptide heterodimerization,
ChemRxiv, 2024.
(DOI: 10.26434/chemrxiv-2024-tkv7w-v2)

Review, Commentary:

1. M Samadarani B S Siriwardena, Takaaki Tsunematsu, Guangying Qi, Naozumi Ishimaru and Yasusei Kudo :
Invasion-Related Factors as Potential Diagnostic and Therapeutic Targets in Oral Squamous Cell Carcinoma-A Review.,
International Journal of Molecular Sciences, Vol.19, No.5, May 2018.
(Tokushima University Institutional Repository: 112412,   DOI: 10.3390/ijms19051462,   PubMed: 29758011,   Elsevier: Scopus)
2. Guangying Qi, Jing Liu, Sisi Mi, Takaaki Tsunematsu, Shengjian Jin, Wenhua Shao, Tian Liu, Naozumi Ishimaru, Bo Tang and Yasusei Kudo :
Aurora Kinase Inhibitors In Head And Neck Cancer.,
Current Topics in Medicinal Chemistry, Vol.18, No.3, 199-213, Jan. 2018.
(Tokushima University Institutional Repository: 113572,   DOI: 10.2174/1568026618666180112163741,   PubMed: 29332580,   Elsevier: Scopus)
3. Yasusei Kudo, Tada Hidesuke, Natsumi Fujiwara, Tada Yoshiko, Takaaki Tsunematsu, Yoichiro Miyake and Naozumi Ishimaru :
Oral environment and cancer,
Genes and Environment, Vol.38, No.13, Aug. 2016.
(Tokushima University Institutional Repository: 114519,   DOI: 10.1186/s41021-016-0042-z,   PubMed: 27482300)
4. Akiko Yamada, Rieko Arakaki, Masako Saito, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
Role of regulatory T cell in the pathogenesis of inflammatory bowel disease.,
World Journal of Gastroenterology : WJG, Vol.22, No.7, 2195-2205, Feb. 2016.
(Tokushima University Institutional Repository: 110976,   DOI: 10.3748/wjg.v22.i7.2195,   PubMed: 26900284,   Elsevier: Scopus)

Proceeding of International Conference:

1. Hirohisa Ogawa, Masahiko Azuma, Umeno Aya, Shimizu Mayuko, Takaaki Tsunematsu, Mayo Kondou, Murotomi Kazutoshi, Koichi Tsuneyama and Yasuhiko Nishioka :
Nerve growth factor exacerbates airway hyperresponsiveness via epithelial damage by neutrophils-derived singlet oxygen in a mouse model of asthma with mixed inflammation,
JSA/WAO Joint Congress 2020, WEB, Sep. 2020.
2. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
APC/CCdh1-mediated degradation of Borealin triggers differentiation of pluripotent stem cells.,
FASEB meeting Ubiquitin and Cellular Regulation, Snowmass Village, CO, USA, May 2018.
3. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Takaaki Tsunematsu, Rieko Arakaki, Yasusei Kudo, Hidehiro Kishimmoto and Naozumi Ishimaru :
Analysis of follicular helper T cells in a mouse model for Sjogren's Syndorome.,
11th International Congress of Autoimmunity, Lisbon, May 2018.
4. Ayumi Sugitani, Mayuko Shimizu, Shu Taira, Takaaki Tsunematsu and Koichi Tsuneyama :
Analysis of fibrogenic roles of liver infiltrating macrophages in a novel Non-alcoholic steatohepatitis (NASH) rat model with liver cirrhosis,
Hepatology, Vol.66, No.S1, 1099A-1100A, Oct. 2017.
5. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
Chromosome passenger complex protein,Borealin is regulated by APC/C Cdh1 ubiquitin ligase complex,
Cold Spring Harbor Laboratory Meeting:The Ubiquitin Family, New York, Apr. 2017.
6. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
The APC/C-Cdh1-Borealin axis has critical role in the maintenance of undifferentiated state in embryonal carcinoma cells,
8th International Conference SUMO, Ubiquitin, UBL Proteins- Implications for Human Diseases, Shanghai, Oct. 2016.
7. Yasusei Kudo, Takaaki Tsunematsu and Naozumi Ishimaru :
Chromosome passenger complex protein,Borealin is regulated by APC/C-Cdh1 ubiquitin ligase complex,
FASEB Ubiquitin & Cellular Regulation, Montana, Jun. 2016.

Proceeding of Domestic Conference:

1. Rieko Arakaki, Takaaki Tsunematsu, Satoru Kisoda, Naozumi Ishimaru and Aya Ushio :
Effect of inhalation exposure to acrbon nanotubes and titanium dioxide on alveolar macrophages,
2. MATSUZAWA Shigefumi, Aya Ushio, RUKA Nagao, Kunihiro Otsuka, TAWARA Hiroaki, Takaaki Tsunematsu and Naozumi Ishimaru :
シェーグレン症候群と胸腺におけるT細胞の分化・成熟の関連についての検討,
第31回日本シェーグレン症候群学会学術集会, Sep. 2023.
3. Jin Shengjian, Takaaki Tsunematsu, Taigo Horiguchi, Yasuhiro Mouri, Wenhua Shao, Keiko Miyoshi, Noriko Mizusawa, Hagita Hiroko, Sarubo Motoharu, Yoshida Kayo, Kaya Yoshida, Natsumi Fujiwara, Kazumi Ozaki, Naozumi Ishimaru and Yasusei Kudo :
The role of deubiquitinating enzyme, OTUB1 in head and neck squamous cell carcinoma (HNSCC) progression,
第82回日本癌学会学術集会, Sep. 2023.
4. TAWARA Hiroaki, Takaaki Tsunematsu, Kunihiro Otsuka, Aya Ushio and Naozumi Ishimaru :
頭頚部扁平上皮癌における染色体パッセンジャー複合体非依存的なBorealin-Survivin相互作用がもたらす新たな機能,
第65回歯科基礎医学会学術大会, Sep. 2023.
5. TAWARA Hiroaki, Takaaki Tsunematsu, RUKA Nagao, MATSUZAWA Shigefumi, Aya Ushio, Kunihiro Otsuka and Naozumi Ishimaru :
Novel role of nuclear Survivin in head and neck squamous carcinoma,
2023 Tokushima Bioscience Retreat, Sep. 2023.
6. TAWARA Hiroaki, Takaaki Tsunematsu, RUKA Nagao, MATSUZAWA Shigefumi, Kunihiro Otsuka, Aya Ushio and Naozumi Ishimaru :
染色体パッセンジャー複合体構成因子Borealin-Survivin相互作用は頭 頚部扁平上皮癌の代謝を制御する,
第34回日本臨床口腔病理学会総会・学術大会, Aug. 2023.
7. Fujimaru Ryo, Michiko Yamashita, Takaaki Tsunematsu, Fukuda Izumi, Katsuyoshi Tamaki and Koichi Tsuneyama :
IGF-2producing hepatocellular carcinoma with non-islet cell tumor hypoglycemia as the paraneoplastic syndrome,
第267回徳島医学会学術集会, Aug. 2023.
8. Takaaki Tsunematsu and Naozumi Ishimaru :
``がんの共食い''の分子機構とその生物学的意義の解明,
第40回分子病理学研究会, Jul. 2023.
9. Kai Tamura, Yuki KAWAHITO, Mami Sato, Kunihiro Otsuka, Takaaki Tsunematsu and Naozumi Ishimaru :
シェーグレン症候群モデルマウスにおける加齢に伴う鼻腔病変の病態解析,
第112回日本病理学会総会, Apr. 2023.
10. Yuki KAWAHITO, Kai Tamura, Mami Sato, Kunihiro Otsuka, Takaaki Tsunematsu and Naozumi Ishimaru :
シェーグレン症候群疾患モデルマウスにおけるMucin19の異常と病態との関連性の解析,
第112回日本病理学会総会, Apr. 2023.
11. Takaaki Tsunematsu, Hiroaki TAWARA, Mami Sato, Kazuki FUKUTA, Kunihiro Otsuka, Aya Ushio and Naozumi Ishimaru :
DNA損傷シグナルによって誘導されるがん細胞の新たな機能とその分子機構,
第112回日本病理学会総会, Apr. 2023.
12. Hiroaki TAWARA, Takaaki Tsunematsu, Kazuki FUKUTA, RUKA Nagao, Mami Sato, Kunihiro Otsuka, Aya Ushio and Naozumi Ishimaru :
染色体パッセンジャー複合体構成因子Borealin-Survivin相互作用は頭頸部扁平上皮癌の代謝を制御する,
第112回日本病理学会総会, Apr. 2023.
13. RUKA Nagao, 山本 安希子, Kunihiro Otsuka, Aya Ushio, TAWARA Hiroaki, TANAKA Hidetaka, Kunihiro Otsuka, Takaaki Tsunematsu and Naozumi Ishimaru :
T細胞の共抑制性受容体を介したシェーグレン症候群の発症機序の解析,
第112回日本病理学会総会, Apr. 2023.
14. Aya Ushio, 松田-Lennikov 真実, Kunihiro Otsuka, Takaaki Tsunematsu, Naozumi Ishimaru and Yousuke Takahama :
自己免疫疾患発症における多様性胸腺髄質上皮細胞の相乗的制御機構,
第112回日本病理学会総会, Apr. 2023.
15. Jin Shengjian, Takaaki Tsunematsu, Taigo Horiguchi, Yasuhiro Mouri, Wenhua Shao, Keiko Miyoshi, Noriko Mizusawa, Hiroko Hagita, YOSHIDA Kayo, Kaya Yoshida, Natsumi Fujiwara, Kazumi Ozaki, Naozumi Ishimaru and Yasusei Kudo :
The role of Deubiquitinating enzyme, OTUB1 in head and neck squamous cell carcinoma (HNSCC) progression,
第61回四国歯学会, Mar. 2023.
16. Takaaki Tsunematsu, TAWARA Hiroaki and Naozumi Ishimaru :
HPV陽性癌における新規脱ユビキチン化酵素複合体の分子機構の解明,
第58回日本口腔組織培養学会学術大会・総会, Dec. 2022.
17. Hiroaki TAWARA, Takaaki Tsunematsu, Nagao RUKA, Kazuki FUKUTA, Mami Sato, Kunihiro Otsuka, Aya Ushio and Naozumi Ishimaru :
頭頸部扁平上皮癌における染色体パッセンジャー複合体構成因子Borealinの高発現がもたらす新たな役割,
第58回日本口腔組織培養学会学術大会・総会, Dec. 2022.
18. Mami Sato, Aya Ushio, Kunihiro Otsuka, Takaaki Tsunematsu and Naozumi Ishimaru :
Th2 response enhances the differentiation into follicular B cells to progress the pulmonary autoimmune lesions in a mouse model of Sjögrens syndrome,
第51回日本免疫学会学術集会, Dec. 2022.
19. Kai Tamura, Yuki KAWAHITO, Mami Sato, Kunihiro Otsuka, Takaaki Tsunematsu and Naozumi Ishimaru :
Pathological analysis of nasal tissue in a murine model of Sjögrens syndrome,
第51回日本免疫学会学術集会, Dec. 2022.
20. Yuki KAWAHITO, Kai Tamura, Mami Sato, Kunihiro Otsuka, Takaaki Tsunematsu and Naozumi Ishimaru :
Role of Mucin 19 in Pathogenesis of a Mouse Model for Sjögren's Syndrome,
第51回日本免疫学会学術集会, Dec. 2022.
21. Takaaki Tsunematsu, Rieko Arakaki, Mami Sato, Kunihiro Otsuka and Naozumi Ishimaru :
Exposure to Multi-Wall Carbon Nanotubes Promotes Fibrous Proliferation by Production of Matrix Metalloproteinase-12 via NF-κB Activation in Chronic Peritonitis,
第51回日本免疫学会学術集会, Dec. 2022.
22. Hiroaki TAWARA, Takaaki Tsunematsu, RUKA Nagao, Mami Sato, Kunihiro Otsuka and Naozumi Ishimaru :
がんにおける染色体パッセンジャー複合体構成因子Borealinの高発現がもたらす新たな機能,
第45回日本分子生物学学会年会, Dec. 2022.
23. Takaaki Tsunematsu and Naozumi Ishimaru :
Cell Cycle machinery unravels the molecular mechanism of Cancer cell cannibalism,
第45回日本分子生物学学会年会, Nov. 2022.
24. Naoyuki Fukuda, Natsumi Takamaru, Kazuya Akita, Keiko Kudoh, Takaaki Tsunematsu, Naozumi Ishimaru and Youji Miyamoto :
超選択的動脈塞栓術を併用して治療した上顎中心性巨細胞肉芽腫の1例,
第67回日本口腔外科学会総会・学術大会, Nov. 2022.
25. Kunihiro Otsuka, Hiroyuki Kondo, Shin-ichi Tsukumo, Rieko Arakaki, Mami Sato, Takaaki Tsunematsu, Naozumi Ishimaru and Koji Yasutomo :
シングルセルRNA-seqとマルチプレックスSpatial解析を基盤としたシェーグレン症候群の標的臓器微小環境変化の解明,
第33回日本臨床口腔病理学会, Sep. 2022.
26. Takaaki Tsunematsu, Hiroaki TAWARA, Mami Sato, Rieko Arakaki, Kunihiro Otsuka, Aya Ushio and Naozumi Ishimaru :
頭頸部扁平上皮癌における染色体パッセンジャー複合体構成因子Borealinの新たな機能,
第64回歯科基礎医学会学術大会, Sep. 2022.
27. Yuki KAWAHITO, Kai Tamura, Mami Sato, Kunihiro Otsuka, Takaaki Tsunematsu and Naozumi Ishimaru :
シェーグレン症候群モデルマウスであるNFS/sldマウスの変異遺伝子Mucin19の発現解析と病態との関連性,
第64回歯科基礎医学会学術大会, Sep. 2022.
28. Kunihiro Otsuka, Shin-ichi Tsukumo, Hiroyuki Kondo, Mami Sato, Hiroaki TAWARA, Takaaki Tsunematsu, Naozumi Ishimaru and Koji Yasutomo :
シングルセルRNA-seqで紐解くシェーグレン症候群モデルに特徴的に出現するT細胞集団の解析,
第64回歯科基礎医学会学術大会, Sep. 2022.
29. Kai Tamura, Yuki KAWAHITO, Mami Sato, Kunihiro Otsuka, Takaaki Tsunematsu and Naozumi Ishimaru :
シェーグレン症候群モデルマウスにおける鼻腔組織の病態解析,
第64回歯科基礎医学会学術大会, Sep. 2022.
30. Mami Sato, Aya Ushio, Kunihiro Otsuka, Takaaki Tsunematsu and Naozumi Ishimaru :
シェーグレン症候群モデルマウス肺病変におけるケモカインの機能分析,
第64回歯科基礎医学会学術大会, Sep. 2022.
31. shengjian jin, Takaaki Tsunematsu, Taigo Horiguchi, Naozumi Ishimaru and Yasusei Kudo :
脱ユビキチン化酵素OTUB1の頭頸部扁平上皮癌の進展における役割,
第64回歯科基礎医学会学術大会, Sep. 2022.
32. Mami Sato, Aya Ushio, Kunihiro Otsuka, Takaaki Tsunematsu and Naozumi Ishimaru :
シェーグレン症候群疾患モデルマウスの肺病変における濾胞B細胞の自己反応性獲得機構の解明,
先端歯学国際教育研究ネットワーク 先端歯学スクール, Aug. 2022.
33. Takaaki Tsunematsu and Naozumi Ishimaru :
頭頚部扁平上皮癌における染色体パッセンジャー複合体構成因子Borealinの新たな機能,
第39回分子病理研究会 内灘かほくシンポジウム, Jul. 2022.
34. Mami Sato, Aya Ushio, Kazuki FUKUTA, Hiroaki TAWARA, Kunihiro Otsuka, Takaaki Tsunematsu, Rieko Arakaki and Naozumi Ishimaru :
Extraglandular lesions in Sjogren's syndorome model mice.,
第20回四国免疫フォーラム, Jun. 2022.
35. Mami Sato, Aya Ushio, Kunihiro Otsuka, Takaaki Tsunematsu, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群モデルマウス肺病変に対するケモカイン群の機能的解析,
第20回四国免疫フォーラム, Jun. 2022.
36. Takaaki Tsunematsu and Naozumi Ishimaru :
口腔扁平上皮癌におけるchromosome passenger complex構成因子Borealinが誘導するSurvivin安定化機構の解明,
第76回日本口腔科学会学術集会, Apr. 2022.
37. Takaaki Tsunematsu, Hiroaki TAWARA, Hidetaka TANAKA, Kazuki FUKUTA, Mami Sato, Kunihiro Otsuka, Rieko Arakaki and Naozumi Ishimaru :
口腔扁平上皮癌におけるBorealinの高発現がもたらすSurvivin安定化機構の解明,
第111回日本病理学会総会, Apr. 2022.
38. Mami Sato, Rieko Arakaki, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群疾患モデルにおける肺病変発症へのCCL6の役割,
第111回日本病理学会総会, Apr. 2022.
39. Yasusei Kudo, Takaaki Tsunematsu and Yasuhiro Mouri :
Aurora-Bキナーゼ阻害剤による多能性幹細胞の分化誘導,
第95回日本薬理学会年会, Mar. 2022.
40. Mami Sato, Takaaki Tsunematsu, Kunihiro Otsuka and Naozumi Ishimaru :
下顎骨病変,
日本病理学会中国四国支部学術集会 (第 137 回スライドカンファレンス), Feb. 2022.
41. Rieko Arakaki, Takaaki Tsunematsu and Naozumi Ishimaru :
Pulmonary immune response and molecular mechanism of fibrosis by inhalation exposure to nanomaterials,
第50回日本免疫学会学術集会, Dec. 2021.
42. Takaaki Tsunematsu, Rieko Arakaki and Naozumi Ishimaru :
HPV陽性癌細胞の増殖に必須の脱ユビキチン化酵素の同定とその分子メカニズムの解明,
第57回口腔組織培養学会学術大会, Nov. 2021.
43. Takaaki Tsunematsu and Naozumi Ishimaru :
がん細胞の老化細胞様変化による新たな機能の獲得とその分子機構,
第63回歯科基礎医学会学術大会 アップデートシンポジウム「がん研究の新たな潮流~歯学基礎研究からの発信~」, Oct. 2021.
44. Mami Sato, 牛尾 綾, 福田 一稀, 俵 宏彰, Kunihiro Otsuka, Takaaki Tsunematsu, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群モデルマウスにおける肺病変の病態探索,
第29回日本シェーグレン症候群学会学術集会, Sep. 2021.
45. Takaaki Tsunematsu :
頭頸部癌におけるDUBsを介したシンセティックリーサリティーの確立への挑戦,
第32回日本臨床口腔病理学会学術大会 若手シンポジウム2(口腔腫瘍研究の最前線), Aug. 2021.
46. Kunihiro Otsuka, Akiko Yamada, Masako Saito, Aya Ushio, Mami Sato, Satoru Kisoda, Wenhua Shao, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
Achaete-Scute Homologue 2-Regulated Follicular Helper T Cells Promote Autoimmunity in a Murine Model for Sjögren Syndrome.,
第32回日本臨床口腔病理学会 奨励賞(実験病理分野), Aug. 2021.
47. Naozumi Ishimaru, Rieko Arakaki, Takaaki Tsunematsu, 高橋 祐次 and 菅野 純 :
ナノマテリアルの吸入暴露による肺免疫応答と線維化の分子機構,
第48回日本毒性学会学術年会, Jul. 2021.
48. Mami Sato, Aya Ushio, Kazuki FUKUTA, Hiroaki TAWARA, Kunihiro Otsuka, Takaaki Tsunematsu, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群モデルマウスにおける腺外病変,
第19回 四国免疫フォーラム, Jun. 2021.
49. Takaaki Tsunematsu, KITAGAWA Takumi, Yasusei Kudo and Naozumi Ishimaru :
口腔扁平上皮癌の進展におけるPeriostinスプライシングバリアントの新たな役割,
第75回日本口腔科学会学術集会, May 2021.
50. Mami Sato, 牛尾 綾, Takaaki Tsunematsu, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群モデルマウスにおける肺病変の解析,
第110回日本病理学会学術集会, Apr. 2021.
51. Rieko Arakaki, 清水 朱里, Mami Sato, 俵 宏彰, Takaaki Tsunematsu and Naozumi Ishimaru :
唾液腺における常在型自然リンパ球の同定とシェーグレン症候群病態への関与,
第110回日本病理学会学術集会, Apr. 2021.
52. Takaaki Tsunematsu, Takumi KITAGAWA, Mami Sato, Rieko Arakaki and Naozumi Ishimaru :
HPV陽性扁平上皮癌細胞の生存に必須な脱ユビキチン化酵素の同定とその役割の解明,
第110回日本病理学会総会, Apr. 2021.
53. Mami Sato, Aya Ushio, Rieko Arakaki, 俵 宏彰, Takaaki Tsunematsu and Naozumi Ishimaru :
シェーグレン症候群モデルマウスにおける腺外病変の発症機序,
四国歯学会第57回例会, Mar. 2021.
54. Mami Sato, Takaaki Tsunematsu, Kunihiro Otsuka and Naozumi Ishimaru :
下顎骨病変,
日本病理学会中国四国支部学術集会 第 137 回スライドカンファレンス, Feb. 2021.
55. Kisoda Satoru, Wenhua Shao, Jin Shengjian, Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
Development of a novel prognostic prediction system for head and neck squamous cell carcinoma,
第79回日本癌学会学術総会, Oct. 2020.
56. Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
多角的アプローチによる口腔癌の発生・進展の分子機構の解明,
第62回歯科基礎医学会学術大会 先端歯学国際教育研究ネットワーク・シンポジウム「歯学研究の今昔と次世代研究」, Sep. 2020.
57. Wenhua Shao, Umeda Masaaki, Takaaki Tsunematsu, Kisoda Satoru and Naozumi Ishimaru :
Novel periostin inform promotes invasion and metastasis in head and neck squamous cell carcinoma.,
第109回 日本病理学会総会, Jul. 2020.
58. Takaaki Tsunematsu, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
染色体パッセンジャー複合体による胎児性癌の未分化性維持機構,
第109回日本病理学会総会, Jul. 2020.
59. Satoru Kisoda, Bunka Sho, Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
口腔癌におけるpartial EMTに関連する遺伝子の悪性度への関与,
第78回日本癌学会学術総会, Sep. 2019.
60. Satoru Kisoda, Wenhua Shao, Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
口腔癌におけるpartial-EMTに関連する遺伝子の悪性度への関与,
第78回日本癌学会学術総会, Sep. 2019.
61. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
The maintenance of pluripotency by chromosome passenger complex in pluripotent stem cells.,
日本RNAi研究会, Aug. 2019.
62. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
染色体パッセンジャー複合体によるAurora-B活性を介した多能性幹細胞の未分化能維持機構,
第16回日本病理学会カンファレンス, Aug. 2019.
63. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
染色体パッセンジャー複合体による未分化能維持機構,
第135回日本薬理学会近畿部会, Jun. 2019.
64. Takaaki Tsunematsu, Hidehiko Kawai, Naozumi Ishimaru, Willium C Earnshaw, Michele Pagano and Yasusei Kudo :
染色体パッセンジャー複合体による多能性幹細胞の未分化能維持機構,
第36回染色体ワークショップ, Jan. 2019.
65. Rieko Arakaki, Nakayama Shinichiro, Aya Ushio, Otsuka Kunihiro, Kisoda Satoshi, Takaaki Tsunematsu, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
The role of the cleaved from IL-33 in pathogenesis of Sjogren's syndorome(SS),
Proceedings of the Japanese Society for Immunology, Dec. 2018.
66. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoru Kisoda, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
A crucial role of follicular helper T cells in autoimmunity of a mouse model for Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Dec. 2018.
67. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
多能性幹細胞においてAPC/CCdh1によるBorealinの分解は分化を誘発する,
第41回日本分子生物学会年会, Nov. 2018.
68. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoru Kisoda, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群疾患モデルの自己免疫病変における濾胞ヘルパーT細胞の役割,
日本シェーグレン症候群学会, Sep. 2018.
69. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoru Kisoda, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群疾患モデルの自己免疫病変における濾胞ヘルパーT細胞の役割,
Japanese Journal of Oral Biology, Sep. 2018.
70. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoru Kisoda, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
Asc/2を介した濾胞ヘルパーT細胞分化異常が自己免疫疾患の病態形成に関与する.,
日本臨床口腔病理学会, Aug. 2018.
71. Mayuko Shimizu, Kazuchika Nishitsuji, 清水 金忠, Hirohisa Ogawa, Takaaki Tsunematsu, 梅本 ひとみ, 森本 友樹, 赤津 裕康, 井之上 浩一 and Koichi Tsuneyama :
TSODマウスにおけるNAFLDの発症およびコーヒーの投与による腸内細菌叢および短鎖脂肪酸プロファイルの変化,
第5回肝臓と糖尿病・代謝研究会, Jul. 2018.
72. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoru Kisoda, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群疾患モデルの自己免疫病変における濾胞ヘルパーT細胞の役割,
分子病理学研究会, Jul. 2018.
73. Shinichiroh Nakayama, Rieko Arakaki, Aya Ushio, Kunihiro Ohtsuka, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群モデルマウス唾液腺におけるIL-33の発現とその役割,
Proceedings of the Japanese Society of Pathology, Vol.107, Jun. 2018.
74. Saki Saijoh, Kunihiro Ohtsuka, Takaaki Tsunematsu, Kunihiro Ohtsuka, Aya Ushio, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
Emi1の過剰発現による人工口腔癌幹細胞の作成,
Proceedings of the Japanese Society of Pathology, Vol.107, Jun. 2018.
75. Yukino Numata, Kunihiro Ohtsuka, Akiko Yamada, Aya Ushio, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群疾患モデルにおけるNotchシグナルの役割,
Proceedings of the Japanese Society of Pathology, Vol.107, Jun. 2018.
76. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群疾患モデルの自己免疫病変における濾胞ヘルパーT細胞の役割,
Proceedings of the Japanese Society of Pathology, Vol.107, Jun. 2018.
77. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Satoko Kujiraoka, Mie Kurosawa, Takaaki Tsunematsu, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群疾患モデルにおける胚中心反応の解析,
第28回日本臨床口腔病理学会, Vol.28, Aug. 2017.
78. Rieko Arakaki, Kohichi Yamada, Masako Saito, Kunihiro Ohtsuka, Akiko Yamada, Takaaki Tsunematsu, Yasusei Kudo, 菅野 純 and Naozumi Ishimaru :
Chronic influence of Multi-walled carbon nanotubes (MWCNT) on immune system,
第106回日本病理学会総会, Vol.106, Apr. 2017.
79. Takaaki Tsunematsu, Yasusei Kudo, Akiko Yamada, Rieko Arakaki, Hirohisa Ogawa, Koichi Tsuneyama and Naozumi Ishimaru :
胎児性癌細胞におけるユビキチンプロテアソーム経路による未分化性維持機構,
第106回日本病理学会総会, Vol.106, Apr. 2017.
80. Aya Ushio, Rieko Arakaki, Akiko Yamada, Kunihiro Ohtsuka, Satoko Kujiraoka, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
シェーグレン症候群の唾液腺におけるマクロファージサブセットと病態への関与,
第106回日本病理学会総会, Vol.106, Apr. 2017.
81. Satoko Kujiraoka, Yasusei Kudo, Takaaki Tsunematsu, Aya Ushio, Kunihiro Ohtsuka, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
歯原性明細胞癌細胞株の樹立とその性状解析,
第106回日本病理学会総会, Vol.106, Apr. 2017.
82. Masaaki Umeda, Takaaki Tsunematsu, Masako Saito, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
口腔癌におけるPeriostinスプライシングバリアントの新たな役割,
第106回日本病理学会総会, Vol.106, Apr. 2017.
83. Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Aya Ushio, Mie Kurosawa, Satoko Kujiraoka, Takaaki Tsunematsu, Yasusei Kudo, Rieko Arakaki and Naozumi Ishimaru :
シェーグレン症候群モデルマウスにおける濾胞ヘルパーT細胞の解析,
第106回日本病理学会総会, Vol.106, Apr. 2017.
84. Ayumi Sugitani, Ryusei Takahashi, Kohki Kai, Mayuko Shimizu, 平 修, 川口 誠, Hirohisa Ogawa, Takaaki Tsunematsu, Koichi Tsuneyama, 野本 一博 and Koichi Tsuneyama :
A case of lipid-rich carcinoma of the breast with numerous hyaline globules,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 492-493, Mar. 2017.
85. Takaaki Tsunematsu, Yasusei Kudo, Akiko Yamada, Rieko Arakaki, Hirohisa Ogawa, Koichi Tsuneyama and Naozumi Ishimaru :
胎児性癌細胞におけるユビキチンプロテアソーム経路による未分化性維持機構,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 356, Mar. 2017.
86. Koichi Tsuneyama, 渡邊 俊介, 高橋 徹行, 馬場 逸人, 森本 友樹, Takaaki Tsunematsu and Hirohisa Ogawa :
自然発症メタボリックシンドローム-NASHモデル動物を用いた少量のコーヒー摂取による病態抑制効果の検討,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 441, Mar. 2017.
87. Hirohisa Ogawa, Takaaki Tsunematsu, 森本 友樹 and Koichi Tsuneyama :
IL-17/好中球は気道粘膜上皮透過性を増加させFGF-2産生を介した気道平滑筋肥厚を誘導する,
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 474, Mar. 2017.
88. 杉谷 鮎美, 高橋 立成, 甲斐 幸樹, Mayuko Shimizu, 平 修, 川口 誠, Hirohisa Ogawa, Takaaki Tsunematsu, Koichi Tsuneyama, 野本 一博 and 常山 幸一 :
A case of lipid-rich carcinoma of the breast with numerous hyaline globules(和訳中),
Proceedings of the Japanese Society of Pathology, Vol.106, No.1, 492-493, Mar. 2017.
89. Rieko Arakaki, Kohichi Yamada, Aya Ushio, Mie Kurosawa, Kunihiro Ohtsuka, Masako Saito, Takaaki Tsunematsu, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
Immunological and toxicological effect of multi-wall carbon nanotubes by whole body inhalation exposure in B6 mice,
第45回日本免疫学会学術集会, Vol.45, Dec. 2016.
90. Akiko Yamada, Rieko Arakaki, Aya Ushio, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
1)Impaired Expansion of Regulatory T cells in a Murine model of Neonatal Thymectomy-induced Sjogrens Syndrome,
第45回日本免疫学会学術集会, Vol.45, Dec. 2016.
91. Aya Ushio, Yasusei Kudo, Satoko Kujiraoka, Kunihiro Ohtsuka, Takaaki Tsunematsu, Akiko Yamada and Naozumi Ishimaru :
上顎骨腫瘍,
日本臨床口腔病理学会総会・学術集会, Vol.27, Aug. 2016.
92. Satoko Kujiraoka, Yasusei Kudo, Takaaki Tsunematsu, Aya Ushio, Kunihiro Ohtsuka, Akiko Yamada and Naozumi Ishimaru :
小児に発生した歯原性下顎骨腫瘍の1例,
日本臨床口腔病理学会総会・学術集会, Vol.27, Aug. 2016.
93. Masaaki Umeda, Takaaki Tsunematsu, Masako Saito, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
口腔扁平上皮癌におけるPeriostinスプライシングバリアントの新たな役割,
第27回日本臨床口腔病理学会総会・学術大会, Aug. 2016.
94. Rieko Arakaki, Takaaki Tsunematsu, Akiko Yamada, Masako Saito, Yasusei Kudo and Naozumi Ishimaru :
全身吸入暴露による多層化カーボンナノチューブの免疫システムへの影響,
第105回日本病理学会総会, Vol.105, No.1, May 2016.
95. Satoko Kujiraoka, Yasusei Kudo, Takaaki Tsunematsu, Tomoyuki Kondoh, Aya Ushio, Kunihiro Ohtsuka, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
顎骨中心性明細胞性腫瘍からの細胞株の樹立とその性状,
第105回日本病理学会総会, Vol.105, No.1, May 2016.
96. Koichi Tsuneyama, Hirohisa Ogawa, Takaaki Tsunematsu and Hisanori Uehara :
新生児期ストレプトゾトシン投与4CS系マウスは通常食飼育によって持続高血糖なしに肝腫瘍を発症する,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 384, Apr. 2016.
97. Hirohisa Ogawa, Takaaki Tsunematsu, Hisanori Uehara and Koichi Tsuneyama :
ダニ抗原経鼻感作はIL-17/好中球を増加させ平滑筋肥厚を伴う気道リモデリングを誘導する,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 386, Apr. 2016.
98. Hisanori Uehara, Hirohisa Ogawa, Takaaki Tsunematsu and Koichi Tsuneyama :
前立腺癌細胞の骨内増殖におけるlipolysis stimulated lipoprotein receptorの役割,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 466, Apr. 2016.
99. Takaaki Tsunematsu, Yasusei Kudo, Akiko Yamada, Rieko Arakaki, Hirohisa Ogawa, Hisanori Uehara, Naozumi Ishimaru and Koichi Tsuneyama :
染色体パッセンジャー複合体タンパク質Borealinのユビキチン分解の意義とその癌化への関与,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 548, Apr. 2016.
100. 良祐 別所, Takaaki Tsunematsu, Hirohisa Ogawa, Hisanori Uehara and Koichi Tsuneyama :
自然発症2型糖尿病モデルマウスにおける膵島の外分泌腺組織への変化がβ細胞の機能不全に果たす役割,
Proceedings of the Japanese Society of Pathology, Vol.105, No.1, 595, Apr. 2016.
101. Rieko Arakaki, Aya Ushio, Mie Kurosawa, Kunihiro Ohtsuka, Akiko Yamada, Masako Saito, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
Analysis of function of macrophages in murine models of Sjogren's syndorome.,
Proceedings of the Japanese Society for Immunology, Nov. 2015.
102. Mie Kurosawa, Akiko Yamada, Rieko Arakaki, Masako Saito, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
Migratory activity of memory T cells in aly/aly mice.,
Proceedings of the Japanese Society for Immunology, Nov. 2015.
103. Tomoyuki Kondoh, Takaaki Tsunematsu, Yasusei Kudo and Naozumi Ishimaru :
自己免疫疾患モデルにおける腫瘍増殖の亢進,
第74回日本癌学会学術総会, Oct. 2015.
104. Takaaki Tsunematsu, Yasusei Kudo, Tomoyuki Kondoh, Aya Ushio, Satoko Kujiraoka, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
染色体パッセンジャー複合体タンパク質Borealinのユビキチン分解とその癌化への関与,
日本病理学会会誌, Vol.104, No.1, 504, May 2015.
105. Satoko Kujiraoka, Yasusei Kudo, Takaaki Tsunematsu, Tomoyuki Kondoh, Aya Ushio, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
口腔癌細胞におけるペリオスチンのスプライシングバリアントの発現とその意義,
日本病理学会会誌, Vol.104, No.1, 497, Apr. 2015.
106. Tomoyuki Kondoh, Takaaki Tsunematsu, Satoko Kujiraoka, Satoko Kujiraoka, Aya Ushio, Akiko Yamada, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
自己免疫疾患モデルを用いた腫瘍増殖制御機構の解明,
日本病理学会会誌, Vol.104, No.1, 497, Apr. 2015.
107. Aya Ushio, Rieko Arakaki, Tomoyuki Kondoh, Satoko Kujiraoka, Takaaki Tsunematsu, Akiko Yamada, Yasusei Kudo and Naozumi Ishimaru :
Analysis of macrophages in the pathogenesis of a murine for Sjogren's syndorome.,
日本病理学会会誌, Vol.104, No.1, 450, Apr. 2015.
108. Yasusei Kudo, Takaaki Tsunematsu, Satoko Kujiraoka, Tomoyuki Kondoh, Aya Ushio, Akiko Yamada, Rieko Arakaki and Naozumi Ishimaru :
顎骨中心性粘表皮癌細胞株の樹立とその性状,
日本病理学会会誌, Vol.104, No.1, 401, Apr. 2015.
109. Rieko Arakaki, Takaaki Tsunematsu, Akiko Yamada, Yasusei Kudo, 菅野 純 and Naozumi Ishimaru :
自己免疫疾患モデルマウスを利用した多層化カーボンナノチューブの免疫システムへの影響,
日本病理学会会誌, Vol.104, No.1, 380, Apr. 2015.

Et cetera, Workshop:

1. 木曽田 暁, 邵 文華, Takaaki Tsunematsu, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
口腔癌における上皮-間葉移行の関与,
徳島県歯科医学大会(四国歯学会第56回例会), Feb. 2020.
2. 邵 文華, Takaaki Tsunematsu, 梅田 将旭, 木曽田 暁, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
口腔癌の進展に関わる新規ペリオスチンスプライシングバリアントの同定,
徳島県歯科医学大会(四国歯学会第56回例会), Feb. 2020.
3. 林 亜門, 清水 朱里, 中西 美緒, 山内 加奈, Mami Sato, 邵 文華, 木曽田 暁, Hitomi Fukui, 木野 倫子, Aya Ushio, Akiko Yamada, Takaaki Tsunematsu, Rieko Arakaki, Yasusei Kudo and Naozumi Ishimaru :
口腔分子病態学分野における免疫・癌研究,
徳島県歯科医学大会(四国歯学会第56回例会), Feb. 2020.
4. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
染色体パッセンジャー複合体による多能性幹細胞の未分化能維持機構,
第37回染色体ワークショップ・第18回核ダイナミクス研究会, Dec. 2019.
5. Takaaki Tsunematsu, Naozumi Ishimaru and Yasusei Kudo :
染色体パッセンジャー複合体によるAurora-B活性を介した多能性幹細胞の未分化能維持機構,
第16回日本病理学会カンファレンス, Aug. 2019.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • Clinical application based on the molecular mechanism of autoantibody production in autoimmunity (Project/Area Number: 23K18361 )
  • Novel pathogenesis and therapeutic strategy of autoimmunity based on immune-tuning molecules (Project/Area Number: 23H00438 )
  • Elucidation of novel high grade transformation mechanism in oral cancer via DNA damage driven "Cancer cannibalism" (Project/Area Number: 22K19630 )
  • 定量プロテオミクスが紐解く新規タンパク質複合体によるHPV陽性癌の新たな病因論 (Project/Area Number: 22H03289 )
  • Estabulishment of synthetic lethality of head and neck squamous cell carcinoma via DUB and development of novel therapeutic strategy (Project/Area Number: 20KK0378 )
  • New molecular mechanism of autoimmunity via deficiency in mucin glycosylation of salivary gland (Project/Area Number: 21K19605 )
  • The novel therapeutic strategy via homologus recombination regulator USP26 in head and neck cancer. (Project/Area Number: 20K18480 )
  • Analysis of Pathogenesis of Autoimmunity through Communication between Organs (Project/Area Number: 19H01070 )
  • Epigenetic analysis of new bone remodeling mechanism in the dentofacial region. (Project/Area Number: 18H03011 )
  • Establishment of highly metastatic mice model of oral squamous cell carcinoma (Project/Area Number: 17K19761 )
  • Study on the generation of oral cancer stem cell and analysis of its nature (Project/Area Number: 17K19760 )
  • Elucidation of novel mechanism to lead DNA over-replication (Project/Area Number: 16H06271 )
  • Clarification of the mechanism of oral carcinogenesis by the defect of degradation of chromosome passenger complex protein (Project/Area Number: 16H05542 )
  • Explore for master regulator of EMT in oral cancer (Project/Area Number: 15K15740 )
  • Search by Researcher Number (70726752)