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Tokushima UniversityGraduate School of Biomedical Sciences薬学域先端薬学教育研究プロジェクト
Tokushima UniversityGraduate School of Biomedical Sciences薬学域Pharmaceutical SciencePharmaceutical Life SciencesDepartment of Molecular Pharmacology
Tokushima UniversityFaculty of Pharmaceutical SciencesPharmaceutical Sciences医薬品探索学講座生命薬理学
Tokushima UniversityGraduate School of Pharmaceutical SciencesPharmaceutical Sciences
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Academic Paper (Judged Full Paper):

1. Hirofumi Hamano, Yasumasa Ikeda, Mitsuhiro Goda, Keijo Fukushima, Seiji Kishi, Masayuki Chuma, Michiko Yamashita, Takahiro Niimura, Kenshi Takechi, Masaki Imanishi, Yoshito Zamami, Yuya Horinouchi, Izawa-Ishizawa Yuki, Licht Miyamoto, Ishizawa Keisuke, Hiromichi Fujino, Toshiaki Tamaki, Ken-ichi Aihara and Koichiro Tsuchiya :
Diphenhydramine may be a preventive medicine against cisplatin-induced kidney toxicity,
Kidney International, Vol.99, No.4, 885-889, 2021.
(Tokushima University Institutional Repository: 115399,   DOI: 10.1016/j.kint.2020.10.041,   PubMed: 33307103)
2. Motofumi Suzuki, Atsumi Urabe, Sayaka Sasaki, Ryo Tsugawa, Satoshi Nishio, Haruka Mukaiyama, Yoshiko Murata, Hiroshi Masuda, M. Sann Aung, Akane Mera, Masaki Takeuchi, Keijo Fukushima, Michika Kanaki, Kaori Kobayashi, Yudai Chiba, Binod Babu Shrestha, Hiromi Nakanishi, T. Watanabe, Atsushi Nakayama, Hiromichi Fujino, Takanori Kobayashi, Keiji Tanino, Naoko Nishizawa and Kosuke Namba :
Development of a mugineic acid family phytosiderophore analog as an iron fertilizer,
Nature Communications, Vol.12, No.1, 1558, 2021.
(Tokushima University Institutional Repository: 116178,   DOI: 10.1038/s41467-021-21837-6,   PubMed: 33692352)
3. Suzu Endo, Akiko Suganami, Keijo Fukushima, Kanaho Senoo, Yumi Araki, W John Regan, Masato Mashimo, Yutaka Tamura and Hiromichi Fujino :
15-Keto-PGE 2 acts as a biased/partial agonist to terminate PGE 2-evoked signaling,
The Journal of Biological Chemistry, Vol.295, No.38, 13338-13352, 2020.
(DOI: 10.1074/jbc.RA120.013988,   PubMed: 32727851)
4. Masaki Imanishi, Yusuke Yamakawa, Keijo Fukushima, Raiki Ikuto, Akiko Maegawa, Yuki Izawa-Ishizawa, Yuya Horinouchi, Masateru Kondo, Masatoshi Kishuku, Mitsuhiro Goda, Yoshito Zamami, Kenshi Takechi, Masayuki Chuma, Yasumasa Ikeda, Koichiro Tsuchiya, Hiromichi Fujino, Koichi Tsuneyama and Keisuke Ishizawa :
Fibroblast-specific ERK5 deficiency changes tumor vasculature and exacerbates tumor progression in a mouse model.,
Naunyn-Schmiedeberg's Archives of Pharmacology, Vol.393, No.7, 1239-1250, 2020.
(DOI: 10.1007/s00210-020-01859-5,   PubMed: 32307577)
5. Hirofumi Hamano, Takahiro Niimua, Yuya Horinouchi, Yoshito Zamami, Kenshi Takechi, Mitsuhiro Goda, Masaki Imanishi, Masayuki Chuma, Yuki Izawa-Ishizawa, Licht Miyamoto, Keijo Fukushima, Hiromichi Fujino, Koichiro Tsuchiya, Keisuke Ishizawa, Toshiaki Tamaki and Yasumasa Ikeda :
Proton pump inhibitors block iron absorption through direct regulation of hepcidin via the aryl hydrocarbon receptor-mediated pathway,
Toxicology Letters, Vol.318, 86-91, 2020.
(Tokushima University Institutional Repository: 113812,   DOI: 10.1016/j.toxlet.2019.10.016,   PubMed: 31669099)
6. Yoshito Zamami, Takahiro Niimura, Naoto Okada, Toshihiro Koyama, Keijo Fukushima, Yuki Izawa-Ishizawa and Keisuke Ishizawa :
Factors Associated With Immune Checkpoint Inhibitor-Related Myocarditis.,
JAMA Oncology, 2019.
(DOI: 10.1001/jamaoncol.2019.3113,   PubMed: 31436802)
7. Naoki Kurata, Natsumi Tokashiki, Keijo Fukushima, Takaya Misao, Nanae Hasuoka, Kana Kitagawa, Masato Mashimo, W John Regan, Toshihiko Murayama and Hiromichi Fujino :
Short chain fatty acid butyrate uptake reduces expressions of prostanoid EP4 receptors and their mediation of cyclooxygenase-2 induction in HCA-7 human colon cancer cells.,
European Journal of Pharmacology, Vol.853, 308-315, 2019.
(DOI: 10.1016/j.ejphar.2019.04.014,   PubMed: 30980797)
8. Hirofumi Hamano, Marin Mitsui, Yoshito Zamami, Kenshi Takechi, Takahiro Nimura, Naoto Okada, Keijo Fukushima, Masaki Imanishi, Masayuki Chuma, Yuya Horinouchi, Yuki Izawa-Ishizawa, Yasushi Kirino, Toshimi Nakamura, Kazuhiko Teraoka, Yasumasa Ikeda, Hiromichi Fujino, Hiroaki Yanagawa, Toshiaki Tamaki and Keisuke Ishizawa :
Irinotecan-induced neutropenia is reduced by oral alkalization drugs: analysis using retrospective chart reviews and the spontaneous reporting database.,
Supportive Care in Cancer, Vol.27, No.3, 849-856, 2019.
(DOI: 10.1007/s00520-018-4367-y,   PubMed: 30062585)
9. Masateru Kondo, Masaki Imanishi, Keijo Fukushima, Raiki Ikuto, Yoichi Murai, Yuya Horinouchi, Yuki Izawa-Ishizawa, Mitsuhiro Goda, Yoshito Zamami, Kenshi Takechi, Masayuki Chuma, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya and Keisuke Ishizawa :
Xanthine Oxidase Inhibition by Febuxostat in Macrophages Suppresses Angiotensin II-induced Aortic Fibrosis.,
American Journal of Hypertension, Vol.32, No.3, 249-256, 2019.
(DOI: 10.1093/ajh/hpy157,   PubMed: 30351343)
10. Naofumi Seira, Kazuyuki Yamagata, Keijo Fukushima, Yumi Araki, Naoki Kurata, Naoki Yanagisawa, Masato Mashimo, Hiroyuki Nakamura, W John Regan, Toshihiko Murayama and Hiromichi Fujino :
Cellular density-dependent increases in HIF-1α compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region.,
Pharmacology Research & Perspectives, Vol.6, No.6, 2018.
(Tokushima University Institutional Repository: 115684,   DOI: 10.1002/prp2.441,   PubMed: 30455960)
11. Masaki Imanishi, Yuki Izawa-Ishizawa, T Sakurada, Y Kohara, Yuya Horinouchi, E Sairyo, Yoshito Zamami, Kenshi Takechi, Masayuki Chuma, Keijo Fukushima, Yasumasa Ikeda, Hiromichi Fujino, M Yoshizumi, Koichiro Tsuchiya, Toshiaki Tamaki and Keisuke Ishizawa :
Nitrosonifedipine, a Photodegradation Product of Nifedipine, Suppresses Pharmacologically Induced Aortic Aneurysm Formation.,
Pharmacology, Vol.102, No.5-6, 281-286, 2018.
(DOI: 10.1159/000492577,   PubMed: 30253416,   Elsevier: Scopus)
12. Yuya Horinouchi, Yasumasa Ikeda, Keijo Fukushima, Masaki Imanishi, Hirofumi Hamano, Yuki Izawa-Ishizawa, Yoshito Zamami, Kenshi Takechi, Licht Miyamoto, Hiromichi Fujino, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki :
Renoprotective effects of a factor Xa inhibitor: fusion of basic research and a database analysis.,
Scientific Reports, Vol.8, No.1, 2018.
(Tokushima University Institutional Repository: 112445,   DOI: 10.1038/s41598-018-29008-2,   PubMed: 30022146)
13. Takahiro Niimura, Yoshito Zamami, Toshihiro Koyama, Yuki Izawa-Ishizawa, Masashi Miyake, Tadashi Koga, Keisaku Harada, Ayako Ohshima, Toru Imai, Yutaka Kondo, Masaki Imanishi, Kenshi Takechi, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Toshiaki Tamaki, Shiro Hinotsu, R Mitsunobu Kano and Keisuke Ishizawa :
Hydrocortisone administration was associated with improved survival in Japanese patients with cardiac arrest.,
Scientific Reports, Vol.7, No.1, 2017.
(Tokushima University Institutional Repository: 112397,   DOI: 10.1038/s41598-017-17686-3,   PubMed: 29263333)
14. Araki Yumi, Suganami Akiko, Endo Suzu, Masuda Yuta, Keijo Fukushima, Regan W. John, Murayama Toshihiko, Tamura Yutaka and Hiromichi Fujino :
PGE1 and E3 show lower efficacies than E2 to -catenin-mediated activity as biased ligands of EP4 prostanoid receptors.,
FEBS Letters, Vol.591, No.22, 3771-3780, 2017.
(DOI: 10.1002/1873-3468.12878,   PubMed: 28986997)

Academic Letter:

1. Keijo Fukushima, Tadanobu Takahashi, Masahiro Takaguchi, Seigo Ito, Chihiro Suzuki, Takashi Agarikuchi, Yuuki Kurebayashi, Akira Minami and Takashi Suzuki :
A I131V Substitution in the Fusion Glycoprotein of Human Parainfluenza Virus Type 1 Enhances Syncytium Formation and Virus Growth.,
Biological & Pharmaceutical Bulletin, Vol.42, No.5, 827-832, 2019.
(DOI: 10.1248/bpb.b18-00714,   PubMed: 31061326,   Elsevier: Scopus)
2. Seira Naofumi, Yanagisawa Naoki, Suganami Akiko, Takuya Honda, Wasai Makiko, Regan W John, Keijo Fukushima, Yamaguchi Naoto, Tamura Yutaka, Arai Takayoshi, Murayama Toshihiko and Hiromichi Fujino :
Anti-cancer effects of MW-03, a novel indole compound, by inducing 15-hydroxyprostaglandin dehydrogenase and cellular growth inhibition in the LS174T human colon cancer cell line,
Biological & Pharmaceutical Bulletin, Vol.40, No.10, 1806-1812, 2017.
(DOI: 10.1248/bpb.b17-00458,   PubMed: 28966256,   Elsevier: Scopus)

Proceeding of International Conference:

1. Yoshito Zamami, Yuki Izawa-Ishizawa, Takahiro Niimura, Mitsuhiro Goda, Naoto Okada, Kenshi Takechi, Masayuki Chuma, Keijo Fukushima, Yasumasa Ikeda, Koichiro Tsuchiya and Keisuke Ishizawa :
Development of therapeutic agents using drug discovery tools and large-scale medical information,
FIP2019, Abu Dhabi, Sep. 2019.
2. Niimura Takahiro, Yoshito Zamami, Yuki Izawa-Ishizawa, Mitsuhiro Goda, Kenshi Takechi, Masayuki Chuma, Keijo Fukushima, Yuya Horinouchi, Hiromichi Fujino, Koichiro Tsuchiya and Keisuke Ishizawa :
Nicorandil improve prognosis of cardiac arrest patient: A large-scale medical information analysis,
FIP2019, Abu Dhabi, Sep. 2019.
3. Yuya Horinouchi, Yasumasa Ikeda, Keijo Fukushima, Masaki Imanishi, Yuki Izawa-Ishizawa, Yoshito Zamami, Hiromichi Fujino, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki :
Utilizing Real-World Big Data in the Search for New Renoprotective Drugs,
Joint Hypertension 2018 Scientific Sessions, Sep. 2018.
4. Seira Naofumi, Yamagata Kazuyuki, Keijo Fukushima, Araki Yumi, Kurata Naoki, Yanagisawa Naoki, Mashimo Masato, Nakamura Hiroyuki, Regan W. John, Murayama Toshihiko and Hiromichi Fujino :
Hypoxia inducible factor-1alpha regulates human EP4 receptor expression by binding to specificity protein-1,
The 3rd Chiba University-Mahidol University Joint Symposium on Pharmaceutical Sciences, Aug. 2018.
5. Yuya Horinouchi, Yasumasa Ikeda, Keijo Fukushima, Masaki Imanishi, Yuki Izawa-Ishizawa, Yoshito Zamami, Hiromichi Fujino, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki :
Renoprotective effects of edoxaban, a factor Xa inhibitor,
18th World Congress of Basic and Clinical Pharmacology, Jul. 2018.
6. Yoshito Zamami, Yuki Izawa-Ishizawa, Kenshi Takechi, Masaki Imanishi, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Toshiaki Tamaki and Keisuke Ishizawa :
Search for drugs that attenuate the anti tumor effect of bevacizumab using adverse event database,
18th World Congress of Basic and Clinical Pharmacology, Jul. 2018.
7. Hiromichi Fujino, Araki Yumi, Suganami Akiko, Endo Suzu, Takano Harumi, Masuda Yuta, Keijo Fukushima, Regan W. John, Murayama Toshihiko and Tamura Yutaka :
PGE1 and E3 show lower efficacies than E2 to beta-catenin-mediated activity as biased ligands of EP4 prostanoid receptors,
18th World Congress of Basic and Clinical Pharmacology, Jul. 2018.

Proceeding of Domestic Conference:

1. Yasumasa Ikeda, Hirofumi Hamano, Mitsuhiro Goda, Keijo Fukushima, Seiji Kishi, Masayuki Chuma, Yoshito Zamami, Licht Miyamoto, 石澤 啓介, Hiromichi Fujino, Ken-ichi Aihara, Koichiro Tsuchiya and Toshiaki Tamaki :
Identification of a candidate drug for the prevention of cisplatin-induced nephrotoxicity by a database analysis -basic research-clinical study,
第94回日本薬理学会年会, Mar. 2021.
2. Nanae Hasuoka, Miho Agata, 間下 雅士, Keijo Fukushima and Hiromichi Fujino :
PGD2およびその代謝物によるCRTH2受容体へのバイアス作用の解明,
日本薬学会第141年会, Mar. 2021.
3. Kiyoka Matsumoto, Yuki Nakano, 高橋 弘喜, 楠屋 陽子, 村山 俊彦, Keijo Fukushima and Hiromichi Fujino :
PGE2による結腸がん細胞内代謝変化の解析,
日本薬学会第141年会, Mar. 2021.
4. Harumi Takano, Kanaho Senoh, Mayu Yamashita, Yumi Araki, Regan John W, Keijo Fukushima and Hiromichi Fujino :
EP4プロスタノイド受容体を介したプロスタグランジンD2のバイアス性による抗癌作用,
第94回日本薬理学会年会, Mar. 2021.
5. Rei Matsumoto, Kaori Ueki, Yuta Masuda, 間下 雅士, Keijo Fukushima and Hiromichi Fujino :
結腸癌転移に関与するヒスタミンH1受容体作用の解明,
Mar. 2021.
6. Takaya Misao, Keijo Fukushima and Hiromichi Fujino :
内因性カンナビノイドによる抗結腸がんメカニズムの解明,
日本薬学会第141年会, 2021.
7. Yasumasa Ikeda, Hirofumi Hamano, Mitsuhiro Goda, Keijo Fukushima, Seiji Kishi, 石澤 啓介, Koichiro Tsuchiya and Toshiaki Tamaki :
シスプラチン起因性腎障害を予防する既存薬の同定,
第63回日本腎臓学会学術総会, Aug. 2020.
8. Manabu Sugiyama, Akito Ohnishi, Takuya Morisaki, Akira Shigenaga, Keijo Fukushima, Akira Otaka and Hiromichi Fujino :
inteinシステムを用いたプロスタノイドEP4受容体の局在解析を目指して,
日本薬学会第140年会, Mar. 2020.
9. Natsuki Yamagiwa, Haruka Kobayashi, Keijo Fukushima, Haruka Okabayashi, 川村 純, 琴浦 聡 and Hiromichi Fujino :
アラキドン酸による神経毒性作用を緩和する有効な生理活性脂質としてのプラズマローゲン種の同定,
日本薬学会第140年会, Mar. 2020.
10. Kana Kitagawa, Ayaka Hamaguchi, 間下 雅士, Regan John W., Keijo Fukushima and Hiromichi Fujino :
ヒト結腸がんHCA-7細胞においてインターロイキン4はEP4プロスタノイド受容体発現を抑制する,
第93回日本薬理学会年会, Mar. 2020.
11. Suzu Endoh, Kanaho Senoh, Harumi Takano, Yumi Araki, Regan John W., Keijo Fukushima and Hiromichi Fujino :
PGE2代謝物 15-keto-PGE2はバイアスアゴニストとしてEP2およびEP4プロスタノイド受容体に作用する,
第93回日本薬理学会年会, Mar. 2020.
12. Hirofumi Hamano, Yasumasa Ikeda, Mitsuhiro Goda, Keijo Fukushima, Seiji Kishi, Kenshi Takechi, Masayuki Chuma, Yoshito Zamami, Yuya Horinouchi, Licht Miyamoto, Hiromichi Fujino, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki :
シスプラチン誘発性腎障害を予防する既存薬物の同定,
第260回徳島医学会学術集会(令和元年度冬期), Feb. 2020.
13. Masayuki Chuma, Mitsuhiro Goda, Takahiro Niimura, Yoshito Zamami, Kenshi Takechi, Yuki Izawa-Ishizawa, 濱野 裕章, 石田 俊介, Takahiro Niimura, Masateru Kondoh, Takashi Bandoh, Naoto Okada, Keijo Fukushima, Hiromichi Fujino, Koichiro Tsuchiya, Yuya Horinouchi, Yasumasa Ikeda, Hiroaki Yanagawa and Keisuke Ishizawa :
ドラッグリポジショニング手法を用いたバンコマイシン関連腎障害の予防薬探索とその有用性の検討,
第13回日本腎臓病薬物療法学会学術集会・総会, Nov. 2019.
14. Yuta Masuda, Kiyoka Matsumoto, Rei Matsumoto, Keijo Fukushima and Hiromichi Fujino :
抗ヒスタミン薬による大腸がん誘発への有害事象の検討,
第26回日本免疫毒性学会学術年会, Jul. 2019.
15. 新村 貴博, Yoshito Zamami, Yuki Izawa-Ishizawa, Mitsuhiro Goda, Kenshi Takechi, Masayuki Chuma, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya and Keisuke Ishizawa :
大規模医療情報を用いたニコランジルの心肺停止後予後改善効果の検討,
医療薬学フォーラム2019/第27回クリニカルファーマシーシンポジウム, Jul. 2019.
16. Mitsuhiro Goda, 斉家 和仁, Akiko Maegawa, Masaya Kanda, Ami Yoshida, Yoichi Murai, Takahiro Niimura, Yuki Izawa-Ishizawa, Yoshito Zamami, Masayuki Chuma, Kenshi Takechi, Hirofumi Hamano, Naoto Okada, Keijo Fukushima, Hiromichi Fujino, Koichiro Tsuchiya, Yuya Horinouchi, Yasumasa Ikeda, Hiroaki Yanagawa and Keisuke Ishizawa :
医療ビッグデータを活用したシスプラチン誘発腎障害に対する新規予防薬の探索とその有効性の検証,
第4回中四国臨床薬理学会, Jul. 2019.
17. Takahiro Niimura, Yoshito Zamami, Yuki Izawa-Ishizawa, Mitsuhiro Goda, Kenshi Takechi, Masayuki Chuma, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya and Keisuke Ishizawa :
医療ビッグデータ解析と基礎研究を融合した薬剤性副作用の機序解明および治療薬の開発,
第29回日本医療薬学会年会 シンポジウム13, Mar. 2019.
18. 近藤 正輝, Masaki Imanishi, Keijo Fukushima, Yuya Horinouchi, Yuki Izawa-Ishizawa, Yuki Izawa-Ishizawa, Mitsuhiro Goda, Yoshito Zamami, Kenshi Takechi, Masayuki Chuma, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya and Keisuke Ishizawa :
キサンチンオキシダーゼ阻害剤による新規血管線維化抑制機構の検討,
日本薬学会第139年会 大学院生シンポジウムGS03, Mar. 2019.
19. Yuya Horinouchi, Yasumasa Ikeda, Hirofumi Hamano, Masaki Imanishi, Keijo Fukushima, Mitsuhiro Goda, Kenshi Takechi, Licht Miyamoto, Yuki Izawa-Ishizawa, Yoshito Zamami, Hiromichi Fujino, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki :
慢性腎不全関連骨格筋萎縮における鉄代謝異常,
第92回日本薬理学会年会, Mar. 2019.
20. Takahiro Niimura, Yoshito Zamami, Yuki Izawa-Ishizawa, Hiroumi Saito, Masaki Imanishi, Kenshi Takechi, Masayuki Chuma, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya and Keisuke Ishizawa :
大規模医療情報データベースおよび遺伝子発現データベースを活用した薬剤性心筋炎に対する予防薬の探索,
第28回日本医療薬学会年会 シンポジウム, Nov. 2018.
21. Yuya Horinouchi, Yasumasa Ikeda, Keijo Fukushima, Hirofumi Hamano, Masaki Imanishi, Yuki Izawa-Ishizawa, Yoshito Zamami, Kenshi Takechi, Hiromichi Fujino, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki :
リアルワールドビッグデータを活用した新規腎保護薬の探索,
第28回日本医療薬学会年会, Nov. 2018.
22. Yuya Horinouchi, Yasumasa Ikeda, Hirofumi Hamano, Masaki Imanishi, Keijo Fukushima, Mitsuhiro Goda, Kenshi Takechi, Licht Miyamoto, Yuki Izawa-Ishizawa, Yoshito Zamami, Hiromichi Fujino, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki :
慢性腎不全関連サルコペニアにおける鉄の関与,
第134回日本薬理学会近畿部会, Nov. 2018.
23. 生藤 来希, Masaki Imanishi, 山川 祐介, Keijo Fukushima, 前川 晃子, Yuya Horinouchi, Yuki Izawa-Ishizawa, Mitsuhiro Goda, Yoshito Zamami, Kenshi Takechi, Masayuki Chuma, Yasumasa Ikeda, Hiromichi Fujino and Koichiro Tsuchiya :
大腸がん増大におけるがん関連線維芽細胞由来ERKSの役割,
第57回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会, Nov. 2018.
24. Yuya Horinouchi, Yasumasa Ikeda, Keijo Fukushima, Yuki Izawa-Ishizawa, Hiromichi Fujino and Toshiaki Tamaki :
リアルワールドデータを活用した新規腎保護薬の探索,
第48回日本腎臓学会西部学術大会, Sep. 2018.
25. 新村 貴博, Yoshito Zamami, Yuki Izawa-Ishizawa, Mitsuhiro Goda, Masaki Imanishi, Kenshi Takechi, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya and Keisuke Ishizawa :
大規模医療情報を活用した新規心肺蘇生後脳症治療薬の探索,
第29回霧島神経薬理フォーラム, Aug. 2018.
26. Masaki Imanishi, Masateru Kondoh, 山川 裕介, 生藤 来希, 村井 陽一, Yoshito Zamami, Kenshi Takechi, Masayuki Chuma, Yuya Horinouchi, Keijo Fukushima, Yuki Izawa-Ishizawa, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya and Keisuke Ishizawa :
Angiotensin II誘発性心臓線維化は線維芽細胞特異的ERK5欠損マウスにおいて亢進される,
第133回日本薬理学会近畿部会, Jun. 2018.
27. Yoshito Zamami, Marin Mitsui, Yuki Izawa-Ishizawa, Kenshi Takechi, Masaki Imanishi, Yuya Horinouchi, Keijo Fukushima, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Toshiaki Tamaki and Keisuke Ishizawa :
有害事象自発報告データベースを活用したベバシズマブの抗腫瘍効果を減弱させる薬剤の探索研究,
日本薬学会第138年会, Mar. 2018.
28. Takahiro Niimura, Yoshito Zamami, Yuki Izawa-Ishizawa, Masaki Imanishi, Kenshi Takechi, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Toshiaki Tamaki and Keisuke Ishizawa :
ドラッグリポジショニング手法を用いた心肺蘇生後脳症治療薬の探索,
日本薬学会第138年会, Mar. 2018.
29. Natsumi Tokashiki, Naoki Kurata, Takaya Misao, Yumi Araki, 清良 尚史, Natsuki Yamagiwa, Manabu Sugiyama, Keijo Fukushima, W John REGAN, 村山 俊彦 and Hiromichi Fujino :
ヒト結腸がんHCA-7 細胞における酪酸によるEP4 受容体発現系への影響,
日本薬学会第138年会, Mar. 2018.
30. Keijo Fukushima, 市川 和哉, 上野 崇宏, 稲垣 孝行, 宮川 泰宏, 千﨑 康司, Hiromichi Fujino and 山田 清文 :
関節リウマチ治療薬を対象とした有害事象自発報告データベースFAERSを用いた感染症リスクの比較,
第256回徳島医学会学術集会, Feb. 2018.
31. Yuya Horinouchi, Yasumasa Ikeda, Keijo Fukushima, Hirofumi Hamano, Masaki Imanishi, Yuki Izawa-Ishizawa, Yoshito Zamami, Hiromichi Fujino, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki :
大規模医療情報データベース解析と基礎研究の融合による新規腎保護薬の探索,
第256回 徳島医学会学術集会(平成29年度冬期), Feb. 2018.
32. Takahiro Niimura, Yoshito Zamami, Yuki Izawa-Ishizawa, Masaki Imanishi, Kenshi Takechi, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Toshiaki Tamaki and Keisuke Ishizawa :
大規模医療情報を活用した心肺停止患者に対するニコランジルの有効性に関する検討,
第256回 徳島医学会学術集会(平成29年度冬期), Feb. 2018.
33. Yuya Horinouchi, Yasumasa Ikeda, Keijo Fukushima, Masaki Imanishi, Yuki Izawa-Ishizawa, Yoshito Zamami, Hiromichi Fujino, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki :
第Xa因子阻害剤の腎保護効果,
第47回日本心脈管作動物質学会, Feb. 2018.
34. Yuya Horinouchi, Yasumasa Ikeda, Keijo Fukushima, Yuki Izawa-Ishizawa, Hiromichi Fujino and Toshiaki Tamaki :
医療ビッグデータを活用した腎保護薬の探索,
2017年度 肥満・糖尿病クラスター・ミニリトリート, Feb. 2018.
35. Yuya Horinouchi, Yasumasa Ikeda, Keijo Fukushima, Masaki Imanishi, Yuki Izawa-Ishizawa, Yoshito Zamami, Hiromichi Fujino, Keisuke Ishizawa, Koichiro Tsuchiya and Toshiaki Tamaki :
第Xa因子阻害薬の腎保護効果,
第10回 心・血管クラスター・ミニリトリート, 2017.
36. Takahiro Niimura, Yoshito Zamami, Yuki Izawa-Ishizawa, Masaki Imanishi, Kenshi Takechi, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Toshiaki Tamaki and Keisuke Ishizawa :
大規模医療情報を用いて新規心肺蘇生後症候群治療薬の開発を志向したドラッグリポジショニング研究,
第38回日本臨床薬理学会学術総会, Dec. 2017.
37. Marin Mitsui, Yoshito Zamami, Yuki Izawa-Ishizawa, Takahiro Niimura, Kenshi Takechi, Masaki Imanishi, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Toshiaki Tamaki and Keisuke Ishizawa :
有害事象自発報告データベースを基にしたベバシズマブと相互作用を起こす薬剤の探索研究,
第56回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会, Oct. 2017.
38. Takahiro Niimura, Yoshito Zamami, Yuki Izawa-Ishizawa, Masaki Imanishi, Kenshi Takechi, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Toshiaki Tamaki and Keisuke Ishizawa :
心肺停止患者の予後に与えるニコランジルの影響-大規模レセプト情報を用いた検討,
第56回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会, Oct. 2017.
39. Shiori Urushizaki, Yoshito Zamami, Yuki Izawa-Ishizawa, Takahiro Niimura, Kenshi Takechi, Masaki Imanishi, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Toshiaki Tamaki and Keisuke Ishizawa :
大規模医療情報を活用して新規心肺蘇生後症候群治療薬の開発を志向したドラッグリポジショニング研究,
第56回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会, Oct. 2017.
40. 荒木 祐美, 菅波 晃子, Suzu Endoh, Hiroyuki Mizuguchi, Keijo Fukushima, W John REGAN, 村山 俊彦, 田村 裕 and Hiromichi Fujino :
PGE1とPGE3のバイアス性と癌抑制機構の解明,
第56回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会, Oct. 2017.
41. Takahiro Niimura, Yoshito Zamami, Yuki Izawa-Ishizawa, Masaki Imanishi, Kenshi Takechi, Keijo Fukushima, Yuya Horinouchi, Yasumasa Ikeda, Hiromichi Fujino, Koichiro Tsuchiya, Toshiaki Tamaki and Keisuke Ishizawa :
心肺蘇生後症候群治療薬の開発を目的としたドラッグリポジショニング研究-大規模医療情報を活用した検討-,
第255回 徳島医学会学術集会, Aug. 2017.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)