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Tokushima UniversityGraduate School of Biomedical Sciences医学域Medical NutritionMedical NutritionDepartment of Nutrition and Metabolism
Tokushima UniversityResearch ClustersResearch Clusters (Registered)1803009 PET-CTを用いたサルコペニアの画期的診断法の開発を目指した研究
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Academic Paper (Judged Full Paper):

1. Yumiko Miyatake, Yuna Mishima, Rie Tsutsumi, Tamaki Otani, Naoya Suemasa, Saeko Masumoto, Masashi Kuroda and Hiroshi Sakaue :
Assessment of insulin resistance in the skeletal muscle of mice using positron emission tomography/computed tomography imaging.,
Biochemical and Biophysical Research Communications, Vol.528, No.3, 499-505, 2020.
(DOI: 10.1016/j.bbrc.2020.05.165,   PubMed: 32513534)
2. Nagakatsu Harada, Yuka Gotoda, Adzumi Hatakeyama, Tadahiko Nakagawa, Yumiko Miyatake, Masashi Kuroda, Saeko Masumoto, Rie Tsutsumi, Yutaka Nakaya and Hiroshi Sakaue :
Differential regulation of Actn2 and Actn3 expression during unfolded protein response in C2C12 myotubes.,
Journal of Muscle Research and Cell Motility, 2020.
(DOI: 10.1007/s10974-020-09582-7,   PubMed: 32451822)
3. Masashi Kuroda, Misa Nishiguchi, Naho Ugawa, Etsuko Ishikawa, Yasuyo Kawabata, Saya Okamoto, Waka Sasaki, Yumiko Miyatake, Mayu Sebe, Saeko Masumoto, Rie Tsutsumi, Nagakatsu Harada and Hiroshi Sakaue :
Interferon regulatory factor 7 mediates obesity-associated MCP-1 transcription.,
PLoS ONE, Vol.15, No.5, e0233390, 2020.
(Tokushima University Institutional Repository: 115245,   DOI: 10.1371/journal.pone.0233390,   PubMed: 32437400)
4. Tetsuya Hosooka, Yusei Hosokawa, Kaku Matsugi, Masakazu Shinohara, Yoko Senga, Yoshikazu Tamori, Chikako Aoki, Sho Matsui, Tsutomu Sasaki, Tadahiro Kitamura, Masashi Kuroda, Hiroshi Sakaue, Kazuhiro Nomura, Kei Yoshino, Yuko Nabatame, Yoshito Itoh, Kanji Yamaguchi, Yoshitake Hayashi, Jun Nakae, Domenico Accili, Takehiko Yokomizo, Susumu Seino, Masato Kasuga and Wataru Ogawa :
The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase-leukotriene B 4 axis,
Proceedings of the National Academy of Sciences of the United States of America, Vol.117, No.21, 11674-11684, 2020.
(DOI: 10.1073/pnas.1921015117,   PubMed: 32393635)
5. Masashi Kuroda, Rumi Onoyama, Waka Sasaki, Mayu Sebe, Tadahiro Kitamura, Saeko Masumoto, Rie Tsutsumi, Nagakatsu Harada and Hiroshi Sakaue :
DNA methylation status influences insulin-induced glucose transport in 3T3-L1 adipocytes by mediating p53 expression.,
Biochemical and Biophysical Research Communications, Vol.525, No.1, 39-45, 2020.
(DOI: 10.1016/j.bbrc.2020.02.038,   PubMed: 32070490)
6. Mayu Sebe, Rie Tsutsumi, Takuro Oyama, T Yousuke Horikawa, Yuta Uemura, Nami Kakuta, Yoko Sakai, Atsushi Morio, Hirotsugu Miyoshi, Takashi Kondo, Tomoaki Urabe, Yuko Noda, Satoshi Kamiya, Noboru Saeki, Masashi Kuroda, Katsuya Tanaka, Yasuo Tsutsumi and Hiroshi Sakaue :
Assessment of postoperative nutritional status and physical function between open surgical aortic valve replacement and transcatheter aortic valve implantation in elderly patients.,
The Journal of Medical Investigation : JMI, Vol.67, No.1.2, 139-144, 2020.
(Tokushima University Institutional Repository: 114644,   DOI: 10.2152/jmi.67.139,   PubMed: 32378597)
7. Masahiro Bando, Saeko Masumoto, Masashi Kuroda, Rie Tsutsumi and Hiroshi Sakaue :
Effect of olive oil consumption on aging in a senescence-accelerated mice-prone 8 (SAMP8) model.,
The Journal of Medical Investigation : JMI, Vol.66, No.3.4, 241-247, 2019.
(Tokushima University Institutional Repository: 113365,   DOI: 10.2152/jmi.66.241,   PubMed: 31656282)
8. Rie Tsutsumi, 瀬部 真由, 別府 香名, 渡辺 涼乃, 尾平 優, Masashi Kuroda and Hiroshi Sakaue :
Management of dysgeusia and dysosmia caused by chemotherapy,
The Journal of Japanese Society for Parenteral and Enteral Nutrition, Vol.33, No.4, 1019-1024, 2018.
(Tokushima University Institutional Repository: 113717,   CiNii: 40021698908)
9. Nagakatsu Harada, Adzumi Hatakeyama, Maiko Okuyama, Yumiko Miyatake, Tadahiko Nakagawa, Masashi Kuroda, Saeko Masumoto, Rie Tsutsumi, Yutaka Nakaya and Hiroshi Sakaue :
Readthrough of ACTN3 577X nonsense mutation produces full-length α-actinin-3 protein.,
Biochemical and Biophysical Research Communications, Vol.502, No.3, 422-428, 2018.
(DOI: 10.1016/j.bbrc.2018.05.193,   PubMed: 29857001)
10. Chikugo Momoko, Sebe Mayu, Rie Tsutsumi, Iuchi Marina, Jun Kishi, Masashi Kuroda, Nagakatsu Harada, Yasuhiko Nishioka and Hiroshi Sakaue :
Effect of Janus kinase inhibition by tofacitinib on body composition and glucose metabolism.,
The Journal of Medical Investigation : JMI, Vol.65, No.3.4, 166-170, 2018.
(Tokushima University Institutional Repository: 112232,   DOI: 10.2152/jmi.65.166,   PubMed: 30282855)
11. Nagakatsu Harada, Maiko Okuyama, Aya Yoshikatsu, Hironori Yamamoto, Saori Ishiwata, Chikako Hamada, Tomoyo Hirose, Masayuki Shono, Masashi Kuroda, Rie Tsutsumi, Jiro Takeo, Yutaka Taketani, Yutaka Nakaya and Hiroshi Sakaue :
Endoplasmic Reticulum Stress in Mice Increases Hepatic Expression of Genes Carrying a Premature Termination Codon via a Nutritional Status-Independent GRP78-Dependent Mechanism.,
Journal of Cellular Biochemistry, Vol.118, No.11, 3810-3824, 2017.
(DOI: 10.1002/jcb.26031,   PubMed: 28383761)
12. Masato Miyake, Masashi Kuroda, Hiroshi Kiyonari, Kenji Takehana, Satoshi Hisanaga, Masatoshi Morimoto, Jun Zhang, Miho Oyadomari, Hiroshi Sakaue and Seiichi Oyadomari :
Ligand-induced rapid skeletal muscle atrophy in HSA-Fv2E-PERK transgenic mice.,
PLoS ONE, Vol.12, No.6, e0179955, 2017.
(Tokushima University Institutional Repository: 114340,   DOI: 10.1371/journal.pone.0179955,   PubMed: 28644884)
13. Yumiko Miyatake, Tetsuya Shiuchi, Kazuaki Mawatari, Satomi Toda, Yasuko Taniguchi, Akari Futami, Fukiko Sato, Masashi Kuroda, Mayu Sebe, Rie Tsutsumi, Nagakatsu Harada, Yasuhiko Minokoshi, Tadahiro Kitamura, Koro Gotoh, Masaki Ueno, Yutaka Nakaya and Hiroshi Sakaue :
Intracerebroventricular injection of ghrelin decreases wheel running activity in rats.,
Peptides, Vol.87, 12-19, 2017.
(Tokushima University Institutional Repository: 113364,   DOI: 10.1016/j.peptides.2016.11.005,   PubMed: 27825986,   Elsevier: Scopus)
14. Masashi Kuroda, Ayako Tominaga, Kasumi Nakagawa, Misa Nishiguchi, Mayu Sebe, Yumiko Miyatake, Tadahiro Kitamura, Rie Tsutsumi, Nagakatsu Harada, Yutaka Nakaya and Hiroshi Sakaue :
DNA Methylation Suppresses Leptin Gene in 3T3-L1 Adipocytes.,
PLoS ONE, Vol.11, No.8, e0160532, 2016.
(Tokushima University Institutional Repository: 110107,   DOI: 10.1371/journal.pone.0160532,   PubMed: 27494408)

Review, Commentary:

1. Masashi Kuroda and Hiroshi Sakaue :
Transcroptional control of thermogenic fat,
Diabetology, Endocrinology & Metabolology, Vol.51, No.1, 23-27, Jul. 2020.
2. Masashi Kuroda and Hiroshi Sakaue :
ADCY3 gene and Obesity,
Endocrinology, Diabetology & Metabolism, Vol.48, No.3, 214-218, Mar. 2019.
(CiNii: 40021856391)
3. Masashi Kuroda and Hiroshi Sakaue :
Adipocyte Death and Chronic Inflammation in Obesity,
The Journal of Medical Investigation : JMI, Vol.64, No.3,4, 193-196, Aug. 2017.
(Tokushima University Institutional Repository: 111114,   DOI: 10.2152/jmi.64.193,   PubMed: 28954980)
4. Masashi Kuroda and Hiroshi Sakaue :
[Role of vitamin D and calcium in obesity and type 2 diabetes].,
Clinical Calcium, Vol.26, No.3, 349-354, Mar. 2016.
(DOI: 10.20837/4201603009,   PubMed: 26923970)

Proceeding of International Conference:

1. Masashi Kuroda, Naho Ugawa, Etsuko Ishikawa, Yasuyo Kawabata, Saya Okamoto, Waka Sasaki, Saeko Masumoto, Rie Tsutsumi and Hiroshi Sakaue :
Transcription factor IRF7 and energy metabolism,
The 11th Scientific Meeting of the Asian Association for the Study of Diabetes., May 2019.
2. Masashi Kuroda :
Adipose tissue-derived protein, MFG-E8, regulates chronic inflammation and obesity-related liver disease,
Asia-Pacific Diabetes and Obesity Study Group symposium 2018, 兵庫県神戸市, Oct. 2018.

Proceeding of Domestic Conference:

1. Mayu Sebe, Rie Tsutsumi, Satoka Senoura, Jun Kishi, Masashi Kuroda, 木下 成三, Yutaka Nakaya, Yasuo Tsutsumi, Yasuhiko Nishioka and Hiroshi Sakaue :
飽和脂肪酸の過剰摂取は関節リウマチ病態の憎悪・骨格筋量の減少を引き起こす,
第23回日本病態栄養学会年次学術集会, Jan. 2020.
2. Kana Takeji, Yuki Yamasaki, Maika Kawai, Yuka Matsumoto, Masashi Kuroda, Rie Tsutsumi and Hiroshi Sakaue :
ストレプドゾトシン抵抗性ラットにおける膵β細胞保護因子の探索,
第23回日本病態栄養学会年次学術集会, Jan. 2020.
3. MISHIMA Yuna, Rie Tsutsumi, Yuka Matsumoto, Kanako Hara, Tamaki Otani, Nanako Ueshima, 神田 彩恵, Masashi Kuroda and Hiroshi Sakaue :
廃用性筋萎縮モデルにおける骨格筋・艦隊者動態の連関による生体機能制御,
第23回日本病態栄養学会年次学術集会, Jan. 2020.
4. Rie Tsutsumi, Mayu Sebe, Jun Kishi, Satoka Senoura, Masashi Kuroda, Yasuhiko Nishioka and Hiroshi Sakaue :
飽和脂肪酸はインスリン抵抗性誘導を介して慢性関節リウマチを増悪させる,
第40回 日本肥満学会, Nov. 2019.
5. Yasuyo Kawabata, Masashi Kuroda, Saya Okamoto, TAMURA Yumi, TOMINAGA Rena, Rie Tsutsumi and Hiroshi Sakaue :
エネルギー代謝調節機構における転写因子IRF7の役割,
第40回 日本肥満学会, Nov. 2019.
6. Kana Takeji, Yuki Yamasaki, Maika Kawai, Yuka Matsumoto, Masashi Kuroda, Rie Tsutsumi and Hiroshi Sakaue :
ストレプトゾトシン抵抗性ラットにおける膵β細胞保護因子の探索,
第40回 日本肥満学会, Nov. 2019.
7. Yasuyo Kawabata, Masashi Kuroda, Saya Okamoto, TAMURA Yumi, TOMINAGA Rena, Rie Tsutsumi and Hiroshi Sakaue :
エネルギー代謝調節機構における転写因子IRF7の役割,
第24回 アディポサイエンス・シンポジウム, Aug. 2019.
8. Yasuyo Kawabata, Masashi Kuroda, Naho Ugawa, Etsuko Ishikawa, Saya Okamoto, Waka Sasaki, Saeko Masumoto, Rie Tsutsumi and Hiroshi Sakaue :
肥大化脂肪細胞における転写因子IRF7の同定と生理的役割の検討,
第62回 日本糖尿病学会, May 2019.
9. MISHIMA Yuna, Rie Tsutsumi, Yumiko Miyatake, Naoya Suemasa, Tamaki Otani, Naoko Kodama, Yohsuke Tamba, Masashi Kuroda, Saeko Masumoto and Hiroshi Sakaue :
PET/CTを用いた代謝異常時の骨格筋における糖取り込みの測定,
第62回 日本糖尿病学会, May 2019.
10. Masashi Kuroda, Etsuko Ishikawa, Naho Ugawa, Saya Okamoto, Yasuyo Kawabata, Waka Sasaki, Saeko Masumoto, Rie Tsutsumi and Hiroshi Sakaue :
脂肪組織慢性炎症及びNASH病態形成における分泌タンパク質MFG-E8の関与,
第62回 日本糖尿病学会, May 2019.
11. Waka Sasaki, Masashi Kuroda, Etsuko Ishikawa, Naho Ugawa, Yasuyo Kawabata, Saeko Masumoto, Rie Tsutsumi and Hiroshi Sakaue :
脱メチル化3T3-L1脂肪細胞のインスリン感受性調節因子の探索,
第39回 日本肥満学会, Oct. 2018.
12. Yasuyo Kawabata, Masashi Kuroda, Etsuko Ishikawa, Naho Ugawa, Waka Sasaki, Saeko Masumoto, Rie Tsutsumi and Hiroshi Sakaue :
肥大化脂肪細胞における転写因子IRF7の同定と生理的役割の検討,
第39回 日本肥満学会, Oct. 2018.
13. Masashi Kuroda and Hiroshi Sakaue :
肥満病態形成におけるIRF7の二つの役割,
第39回 日本肥満学会, Oct. 2018.
14. Masashi Kuroda, Naho Ugawa, Etsuko Ishikawa, Yasuyo Kawabata, Waka Sasaki, Saeko Masumoto, Rie Tsutsumi and Hiroshi Sakaue :
エネルギー代謝における転写因子IRF7の役割,
第23回アディポサイエンス・シンポジウム, Aug. 2018.
15. Naho Ugawa, Masashi Kuroda, Etsuko Ishikawa, Saeko Masumoto, Rie Tsutsumi, Nagakatsu Harada and Hiroshi Sakaue :
肥大化脂肪細胞における転写因子 IRF7 の同定と機能解析,
第61回 日本糖尿病学会, May 2018.
16. Masashi Kuroda, Etsuko Ishikawa, Naho Ugawa, Saeko Masumoto, Rie Tsutsumi, Nagakatsu Harada and Hiroshi Sakaue :
脂肪組織慢性炎症及びNASH病態形成に対するMFG-E8の関与,
第61回 日本糖尿病学会, May 2018.
17. Masashi Kuroda, Etsuko Ishikawa, Naho Ugawa, Saeko Masumoto, Rie Tsutsumi, Nagakatsu Harada and Hiroshi Sakaue :
Adipose tissue-derived protein, MFG-E8, regulates chronic inflammation and obesity-related liver disease,
第91回 日本内分泌学会, Apr. 2018.
18. Rie Tsutsumi, Jiro Takeo, Masahiro Bando, Mayu Sebe, Yuki Yamasaki, Yohsuke Tamba, Yuko Miyahara, Masashi Kuroda, Saeko Masumoto, Nagakatsu Harada and Hiroshi Sakaue :
魚油由来長鎖モノエン脂肪酸の上腕動脈内皮機能に与える効果の検討,
第38回 日本肥満学会, Oct. 2017.
19. Rumi Onoyama, Masashi Kuroda, Misa Nishiguchi, Naho Ugawa, Etsuko Ishikawa, Saeko Masumoto, Rie Tsutsumi, Nagakatsu Harada and Hiroshi Sakaue :
転写制御領域解析システムを用いた3T3-L1脂肪細胞のインスリン感受性調節因子の探索,
第38回 日本肥満学会, Oct. 2017.
20. Etsuko Ishikawa, Masashi Kuroda, Misa Nishiguchi, Rumi Onoyama, Naho Ugawa, Saeko Masumoto, Rie Tsutsumi, Nagakatsu Harada and Hiroshi Sakaue :
脂肪組織慢性炎症及びNASH病態形成に対するMFG-E8の関与,
第38回 日本肥満学会, Oct. 2017.
21. Masashi Kuroda, Misa Nishiguchi, Rumi Onoyama, Naho Ugawa, Etsuko Ishikawa, Saeko Masumoto, Rie Tsutsumi, Nagakatsu Harada and Hiroshi Sakaue :
脂肪細胞における転写因子IRF7の同定及び機能解析,
第22回 アディポサイエンス・シンポジウム, Aug. 2017.
22. Misa Nishiguchi, Masashi Kuroda, Rumi Onoyama, Naho Ugawa, Rie Tsutsumi, Nagakatsu Harada and Hiroshi Sakaue :
肥大化脂肪細胞における転写因子IRF7の同定と機能解析,
第60回日本糖尿病学会年次学術集会, May 2017.
23. Rumi Onoyama, Masashi Kuroda, Misa Nisiguchi, Naho Ugawa, Rie Tsutsumi, Nagakatsu Harada and Hiroshi Sakaue :
3T3-L1脂肪細胞のインスリン感受性に対するDNAメチル化の制御機構,
第60回日本糖尿病学会年次学術集会, May 2017.
24. Masashi Kuroda, Misa Nishiguchi, Rumi Onoyama, Naho Ugawa, Rie Tsutsumi, Nagakatsu Harada and Hiroshi Sakaue :
新規肥満関連転写因子IRF7によるMCP-1発現制御機構の解析,
第90回 日本内分泌学会学術集会, Apr. 2017.
25. Yohsuke Tamba, Jiro Takeo, Masahiro Bandoh, Mayu Sebe, Yuki Yamasaki, Daiju Fukuda, Yuko Miyahara, Yumiko Miyatake, Naoya Suemasa, Masashi Kuroda, Saeko Masumoto, Nagakatsu Harada, Rie Tsutsumi, Masataka Sata and Hiroshi Sakaue :
魚油由来長鎖モノエン脂肪酸は抗動脈硬化作用を有する,
第21回病態栄養学会年次学術集会, Jan. 2017.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 肥満形成過程における褐色脂肪機能不全メカニズムの解明 (Project/Area Number: 20K19709 )
  • Basic and applied research of long-chained unsaturated fatty acid for preventing anti- arteriosclerosis (Project/Area Number: 19H04055 )
  • Regulation of macrophage function by adipose derived secreted protein and its involvement in NASH (Project/Area Number: 18K16205 )
  • Search by Researcher Number (00803579)