Tokushima University / Educator and Researcher Directory --- Nishiyama, Yuichi

Personal Web Page

https://researchmap.jp/y-nishi (researchmap)

Field of Study

○	Radiation Biology, Radiation Science

Subject of Study

○	p53制御によって正常組織への副作用を軽減する新規放射線防護剤の開発

Book / Paper

Academic Paper (Judged Full Paper):

1.	GHOSH SHARMILA, Akinori Morita, Yuichi Nishiyama, Masahiro Sakaue, Ken Fujiwara, Daiki Morita, Yuichiro Sonoyama, Yuichi Higashi and Megumi Sasatani : Rectal Epithelial Stem Cell Kinetics in Acute Radiation Proctitis., International Journal of Molecular Sciences, Vol.25, No.20, 11252, 2024. (Keyword) Animals / Proctitis / Receptors, G-Protein-Coupled / Mice / Stem Cells / Radiation Injuries / Rectum / Kinetics / Epithelial Cells / Intestinal Mucosa / Mice, Transgenic / Mice, Inbred C57BL / Dose-Response Relationship, Radiation / Gene Knock-In Techniques (Tokushima University Institutional Repository) ● Metadata: 119643 (Link to Publication Site) ● Publication site (DOI): 10.3390/ijms252011252 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 39457033 ● Search Scopus @ Elsevier (PMID): 39457033 ● Search Scopus @ Elsevier (DOI): 10.3390/ijms252011252 (Tokushima University Institutional Repository: 119643, DOI: 10.3390/ijms252011252, PubMed: 39457033)
2.	Yukako Nishiyama, Kenji Yabuuchi, Yuichi Nishiyama, Yasuo Kambara, Youko Ikushima and Tetsuya Enishi : Crossed raised arm position improves the flow of contrast medium in torso contrast-enhanced computed Tomography, Radiography, Vol.30, No.2, 681-687, 2024. (Summary) This retrospective cohort study examined the effects of the crossed raised arm (CRA) position in contrast-enhanced computed tomography (CECT) on contrast medium influx and image quality relative to the conventional position. Contrast medium influx into the collateral veins on CECT images was evaluated in 92 participants. The CT values of the pulmonary artery, descending aorta, and spleen were obtained in both positions and compared. Anatomical changes in the diameters and area of the subclavian vein and costoclavicular distance were also analyzed. Contras 27 and 6 patients in the conventional and CRA positions, respectively. The influx risk ratio in the CRA position versus that in the conventional position was 0.22 (95% confidence interval, 0.10-0.51). Elevations in the median CT value of the pulmonary artery, descending aorta, and spleen in the CRA position were 7.0% (p < .001), 7.4% (p < .001), and 9.8% (p < .001), respectively. Enlargements in the major and minor diameters of the subclavian vein, subclavian vein area, and costoclavicular distance in the CRA position versus those in the conventional position were 19.3% (p < .001), 28.1% (p < .001), 53.6%, and 30.0% (p < .001), respectively. The CRA position effectively prevented contrast medium influx into the collateral veins due to SVS and increased CT values in the target organs in CECT. The diameters and area of the subclavian vein and costoclavicular distance were enlarged at the thoracic outlet, which improved the flow of the contrast medium into the targeted organs. The CRA position can contribute to obtaining better CECT images during common clinical assessments at no additional cost. (Keyword) Humans / Arm / Retrospective Studies / Tomography, X-Ray Computed / Contrast Media / Abdomen (Link to Publication Site) ● Publication site (DOI): 10.1016/j.radi.2024.02.004 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 38364708 ● Search Scopus @ Elsevier (PMID): 38364708 ● Search Scopus @ Elsevier (DOI): 10.1016/j.radi.2024.02.004 (DOI: 10.1016/j.radi.2024.02.004, PubMed: 38364708)
3.	Hidetoshi Satoh, Shintaroh Ochi, Kosuke Mizuno, Yutaka Saga, Shohei Ujita, Mihiro Toyoda, Yuichi Nishiyama, Kasumi Tada, Yosuke Matsushita, Yuichi Deguchi, Keiji Suzuki, Yoshimasa Tanaka, Hiroshi Ueda, Toshiya Inaba, Yoshio Hosoi, Akinori Morita and Shin Aoki : Design, synthesis and biological evaluation of 2-pyrrolone derivatives as radioprotectors., Bioorganic & Medicinal Chemistry, Vol.67, 2022. (Summary) It is known that p53 is an important transcription factor and plays a central role in ionizing radiation (IR)-induced DNA damage responses such as cell cycle arrest, DNA repair and apoptosis. We previously reported that regulating p53 protein is an effective strategy for modulating cell fate by reducing the acute side effects of radiation therapy. Herein, we report on the discovery of STK160830 as a new radioprotector from a chemical library at The University of Tokyo and the design, synthesis and biological evaluation of its derivatives. The radioprotective activity of STK160830 itself and its derivatives that were synthesized in this work was evaluated using a leukemia cell line, MOLT-4 cells as a model of normal cells that express the p53 protein in a structure-activity relationships (SAR) study. The experimental results suggest that a direct relationship exists between the inhibitory effect of these STK160830 derivatives on the expression level of p53 and their radioprotective activity and that the suppression of p53 by STK160830 derivatives contribute to protecting MOLT-4 cells from apoptosis that is induced by exposure to radiation. (Keyword) Apoptosis / DNA Damage / DNA Repair / Tumor Suppressor Protein p53 (Link to Publication Site) ● Publication site (DOI): 10.1016/j.bmc.2022.116764 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 35635928 ● Search Scopus @ Elsevier (PMID): 35635928 ● Search Scopus @ Elsevier (DOI): 10.1016/j.bmc.2022.116764 (DOI: 10.1016/j.bmc.2022.116764, PubMed: 35635928)
4.	Masahide Tominaga, Yukari Nagayasu, Motoharu Sasaki, Furuta Takuya, Hiroaki Hayashi, Masataka Oita, Yuichi Nishiyama and Akihiro Haga : Influence of distant scatterer on air kerma measurement in the evaluation of diagnostic X-rays using Monte Carlo simulation, Radiological Physics and Technology, Vol.14, No.4, 381-389, 2021. (Summary) The evaluation of the entrance surface dose (ESD) ensures safe radiation doses for X-ray imaging patients. The air kerma free-in-air value used to estimate ESD may be affected by those X-rays that scatter from the scatterer placed behind the chamber at the time of measurement, thereby leading to assessment errors. Therefore, the influence of scattered radiation on air kerma measurements was investigated. Monte Carlo simulations were performed for various detector-to-scatterer distances and scatterer materials. The simulation results were compared with actual measurements to confirm the simulation accuracy. The source-chamber distance was set to 50 and 100 cm for the experimental measurements and simulation, respectively, and the chamber-scatterer distance was varied. The Monte Carlo simulation results reproduced the actual measurements with an accuracy of 3.5%. The effect of backscattering varied with the tube voltage and irradiation field size. The effect was observed in the order of prominence for the following scatterer materials: water-equivalent phantom, acrylic, concrete, lead, and iron. Furthermore, this effect decreased exponentially with increasing chamber-scatterer distance. For a field size of 10 × 10 cm, the finite-distance backscatter factor decreased with an increasing chamber-scatterer distance for all materials. The cause of backscattering in diagnostic X-ray energy regions differs depending on the scatterer material, as well as the photon energy and field size. Backscattering decreases exponentially as the distance between the detector and scatterer increases. (Keyword) Air kerma / Backscattering / Dosimetry / Monte Carlo simulation (Link to Publication Site) ● Publication site (DOI): 10.1007/s12194-021-00641-3 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34716568 ● Search Scopus @ Elsevier (PMID): 34716568 ● Search Scopus @ Elsevier (DOI): 10.1007/s12194-021-00641-3 (DOI: 10.1007/s12194-021-00641-3, PubMed: 34716568)
5.	Akinori Morita, Shintaro Ochi, Hidetoshi Satoh, Shohei Ujita, Yosuke Matsushita, Kasumi Tada, Mihiro Toyoda, Yuichi Nishiyama, Kosuke Mizuno, Yuichi Deguchi, Keiji Suzuki, Yoshimasa Tanaka, Hiroshi Ueda, Toshiya Inaba, Yoshio Hosoi and Shin Aoki : A Novel RNA Synthesis Inhibitor, STK160830, Has Negligible DNA-Intercalating Activity for Triggering A p53 Response, and Can Inhibit p53-Dependent Apoptosis., Life, Vol.11, No.10, 2021. (Summary) RNA synthesis inhibitors and protein synthesis inhibitors are useful for investigating whether biological events with unknown mechanisms require transcription or translation; however, the dependence of RNA synthesis has been difficult to verify because many RNA synthesis inhibitors cause adverse events that trigger a p53 response. In this study, we screened a library containing 9600 core compounds and obtained STK160830 that shows anti-apoptotic effects in irradiated wild-type-p53-bearing human T-cell leukemia MOLT-4 cells and murine thymocytes. In many of the p53-impaired cells and p53-knockdown cells tested, STK160830 did not show a remarkable anti-apoptotic effect, suggesting that the anti-apoptotic activity is p53-dependent. In the expression analysis of p53, p53-target gene products, and reference proteins by immunoblotting, STK160830 down-regulated the expression of many of the proteins examined, and the downregulation correlated strongly with its inhibitory effect on cell death. mRNA expression analyses by qPCR and nascent RNA capture kit revealed that STK160830 showed a decreased mRNA expression, which was similar to that induced by the RNA synthesis inhibitor actinomycin D but differed to some extent. Furthermore, unlike other RNA synthesis inhibitors such as actinomycin D, p53 accumulation by STK160830 alone was negligible, and a DNA melting-curve analysis showed very weak DNA-intercalating activity, indicating that STK160830 is a useful inhibitor for RNA synthesis without triggering p53-mediated damage responses. (Tokushima University Institutional Repository) ● Metadata: 116405 (Link to Publication Site) ● Publication site (DOI): 10.3390/life11101087 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34685458 ● Search Scopus @ Elsevier (PMID): 34685458 ● Search Scopus @ Elsevier (DOI): 10.3390/life11101087 (Tokushima University Institutional Repository: 116405, DOI: 10.3390/life11101087, PubMed: 34685458)
6.	Yuichi Nishiyama, Akinori Morita, Shogo Tatsuta, Misaki Kanamaru, Masahiro Sakaue, Kenta Ueda, Manami Shono, Rie Fujita, Bing Wang, Yoshio Hosoi, Shin Aoki and Takeshi Sugai : Isorhamnetin Promotes 53BP1 Recruitment through the Enhancement of ATM Phosphorylation and Protects Mice from Radiation Gastrointestinal Syndrome., Genes, Vol.12, No.10, 2021. (Summary) Flavonoids are a subclass of polyphenols which are attractive, due to possessing various physiological activities, including a radioprotective effect. Tumor suppressor p53 is a primary regulator in the radiation response and is involved in the pathogenesis of radiation injuries. In this study, we revealed that isorhamnetin inhibited radiation cell death, and investigated its action mechanism focusing on DNA damage response. Although isorhamnetin moderated p53 activity, it promoted phosphorylation of ataxia telangiectasia mutated (ATM) and enhanced 53BP1 recruitment in irradiated cells. The radioprotective effect of isorhamnetin was not observed in the presence of ATM inhibitor, indicating that its protective effect was dependent on ATM. Furthermore, isorhamnetin-treated mice survived gastrointestinal death caused by a lethal dose of abdominal irradiation. These findings suggested that isorhamnetin enhances the ATM-dependent DNA repair process, which is presumably associated with the suppressive effect against GI syndrome. (Tokushima University Institutional Repository) ● Metadata: 116406 (Link to Publication Site) ● Publication site (DOI): 10.3390/genes12101514 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34680909 ● Search Scopus @ Elsevier (PMID): 34680909 ● Search Scopus @ Elsevier (DOI): 10.3390/genes12101514 (Tokushima University Institutional Repository: 116406, DOI: 10.3390/genes12101514, PubMed: 34680909)
7.	Yuichi Nishiyama, Akinori Morita, Bing Wang, Takuma Sakai, Dwi Ramadhani, Kaoru Tanaka, Megumi Sasatani, Shintaro Ochi, Masahide Tominaga, Hitoshi Ikushima, Junji Ueno, Mitsuru Nenoi and Shin Aoki : Evaluation of sodium orthovanadate as a radioprotective agent under total-body irradiation and partial-body irradiation conditions in mice., International Journal of Radiation Biology, Vol.97, No.9, 1241-1251, 2021. (Tokushima University Institutional Repository) ● Metadata: 116409 (Link to Publication Site) ● Publication site (DOI): 10.1080/09553002.2021.1941377 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 34125648 ● Search Scopus @ Elsevier (PMID): 34125648 ● Search Scopus @ Elsevier (DOI): 10.1080/09553002.2021.1941377 (Tokushima University Institutional Repository: 116409, DOI: 10.1080/09553002.2021.1941377, PubMed: 34125648)
8.	Akinori Morita, Bing Wang, Kaoru Tanaka, Takanori Katsube, Masahiro Murakami, Takashi Shimokawa, Yuichi Nishiyama, Shintaro Ochi, Hidetoshi Satoh, Mitsuru Nenoi and Shin Aoki : Protective Effects of p53 Regulatory Agents Against High-LET Radiation-Induced Injury in Mice., Frontiers in Public Health, Vol.8, 2020. (Summary) < 0.02), but not iron-ion irradiation, suggesting the moderate relief of the intestinal damage. These results demonstrated the effectiveness of p53 regulators on acute radiation syndrome induced by high-LET radiation. (Tokushima University Institutional Repository) ● Metadata: 115457 (Link to Publication Site) ● Publication site (DOI): 10.3389/fpubh.2020.601124 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 33344403 ● Summary page in Scopus @ Elsevier: 2-s2.0-85098120572 (Tokushima University Institutional Repository: 115457, DOI: 10.3389/fpubh.2020.601124, PubMed: 33344403, Elsevier: Scopus)
9.	Hiroya Asou, Naoyuki Imada, Yuichi Nishiyama, Tomoyasu Sato and Katsuhiro Ichikawa : Automated determination of cardiac rest period on whole-heart coronary magnetic resonance angiography by extracting high-speed motion of coronary arteries., Clinical Imaging, Vol.52, 183-188, 2018. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.clinimag.2018.07.006 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 30098491 ● Search Scopus @ Elsevier (PMID): 30098491 ● Search Scopus @ Elsevier (DOI): 10.1016/j.clinimag.2018.07.006 (DOI: 10.1016/j.clinimag.2018.07.006, PubMed: 30098491)
10.	Yasushi Yamamoto, Yuichi Nishiyama, Masuo Haramoto, Takumi Sota, Masahiro Miyai, Taku Uchibe, Nobuhiro Yada, Yukako Nishiyama and Hajime Kitagaki : Improvement in the quantification of striatal tracer uptake in single-photon emission computed tomography with 123I-ioflupane using a cadmium-zinc-telluride semiconductor camera., Shimane Journal of Medical Science, Vol.34, No.1, 35-40, 2017. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050282813462935808 (CiNii: 1050282813462935808)
11.	Yuichi Nishiyama, Hidekazu Kanayama, Hiroshi Mori, Keiji Tada, Yasushi Yamamoto, Takashi Katsube, Haruo Takeshita, Kazunori Kawakami and Hajime Kitagaki : Whole brain analysis of postmortem density changes of grey and white matter on computed tomography by statistical parametric mapping., European Radiology, Vol.27, No.6, 2317-2325, 2016. (Summary) The SPM technique demonstrated typical postmortem changes on brain CT scans, and revealed that the unclear GM-WM interface on early PMCT scans is caused by a rapid decrease in cortical GM density combined with a delayed increase in WM density. SPM may be useful for assessment of whole brain postmortem changes. (Keyword) Adult / Autopsy / Brain Edema / Brain Mapping / Female / Gray Matter / Humans / Postmortem Changes / Retrospective Studies / White Matter (Link to Publication Site) ● Publication site (DOI): 10.1007/s00330-016-4633-7 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27770229 ● Search Scopus @ Elsevier (PMID): 27770229 ● Search Scopus @ Elsevier (DOI): 10.1007/s00330-016-4633-7 (DOI: 10.1007/s00330-016-4633-7, PubMed: 27770229)
12.	Yukako Nishiyama, Keiji Tada, Yuichi Nishiyama, Hiroshi Mori, Mitsunari Maruyama, Takashi Katsube, Nobuko Yamamoto, Hidekazu Kanayama, Yasushi Yamamoto and Hajime Kitagaki : Effect of the forward-projected model-based iterative reconstruction solution algorithm on image quality and radiation dose in pediatric cardiac computed tomography., Pediatric Radiology, Vol.46, No.12, 1663-1670, 2016. (Link to Publication Site) ● Publication site (DOI): 10.1007/s00247-016-3676-x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 27531216 ● Search Scopus @ Elsevier (PMID): 27531216 ● Search Scopus @ Elsevier (DOI): 10.1007/s00247-016-3676-x (DOI: 10.1007/s00247-016-3676-x, PubMed: 27531216)
13.	Keiko Yamato, Takahiro Kataoka, Yuichi Nishiyama, Yuji Takata, Reo Etani and Kiyonori Yamaoka : Study on antidepressant-like eff¬ects of radon inhalation on forced swim induced depression in mice., Radioisotopes, Vol.65, No.12, 493-506, 2016. (Link to Publication Site) ● Publication site (DOI): 10.3769/radioisotopes.65.493 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.3769/radioisotopes.65.493 (DOI: 10.3769/radioisotopes.65.493)
14.	Yuichi Nishiyama, Takahiro Kataoka, Keiko Yamato, Reo Etani, Tekehito Taguchi and Kiyonori Yamaoka : Radon inhalation suppresses nephropathy in streptozotocin-induced type-1 diabetic mice, Journal of Nuclear Science and Technology (Japan), Vol.53, No.6, 909-915, 2016. (Link to Publication Site) ● Publication site (DOI): 10.1080/00223131.2015.1078751 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84940521185 (DOI: 10.1080/00223131.2015.1078751, Elsevier: Scopus)
15.	Yuichi Nishiyama, Tadashi Hanafusa, Jun Yamashita, Yoko Yamamoto and Toshiro Ono : Adsorption and removal of strontium in aqueous solution by synthetic hydroxyapatite., Journal of Radioanalytical and Nuclear Chemistry, Vol.307, 1279-1285, 2015. (Link to Publication Site) ● Publication site (DOI): 10.1007/s10967-015-4228-9 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 26834308 ● Search Scopus @ Elsevier (PMID): 26834308 ● Search Scopus @ Elsevier (DOI): 10.1007/s10967-015-4228-9 (DOI: 10.1007/s10967-015-4228-9, PubMed: 26834308)
16.	Reo Etani, Takahiro Kataoka, Yuichi Nishiyama, Yuji Yakata and Kiyonori Yamaoka : Combined effects of radon inhalation and antioxidant vitamin administration on acute alcohol-induced hepatopathy in mice., Journal of Nuclear Science and Technology (Japan), Vol.52, No.12, 1512-1518, 2015. (Link to Publication Site) ● Publication site (DOI): 10.1080/00223131.2015.1014875 (Link to Search Site for Scientific Articles) ● Summary page in Scopus @ Elsevier: 2-s2.0-84945440296 (DOI: 10.1080/00223131.2015.1014875, Elsevier: Scopus)
17.	Takahiro Kataoka, Reo Etani, Yuji Takata, Yuichi Nishiyama, Atsushi Kawabe, Masayuki Kumashiro, Takehito Taguchi and Kiyonori Yamaoka : Radon inhalation protects against transient global cerebral ischemic injury in gerbils., Inflammation, Vol.37, No.5, 1675-1682, 2014. (Link to Publication Site) ● Publication site (DOI): 10.1007/s10753-014-9896-z (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 24792782 ● Search Scopus @ Elsevier (PMID): 24792782 ● Search Scopus @ Elsevier (DOI): 10.1007/s10753-014-9896-z (DOI: 10.1007/s10753-014-9896-z, PubMed: 24792782)
18.	Takahiro Kataoka, Yuji Takata, Reo Etani, Yuichi Nishiyama, Atsushi Kawabe, Katsumi Hanamoto, Takehito Taguchi and Kiyonori Yamaoka : Effects of cream containing ultralow volume radionuclides on carrageenan-induced inflammatory paw edema in mice., Biochemistry & Physiology, Vol.3, No.2, 133, 2014. (Link to Publication Site) ● Publication site (DOI): 10.4172/2168-9652.1000133 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.4172/2168-9652.1000133 (DOI: 10.4172/2168-9652.1000133)
19.	Keiko Yamato, Takahiro Kataoka, Yuichi Nishiyama, Takehito Taguchi and Kiyonori Yamaoka : Antinociceptive effects of radon inhalation on formalin-induced inflammatory pain in mice., Inflammation, Vol.36, No.2, 355-363, 2013. (Link to Publication Site) ● Publication site (DOI): 10.1007/s10753-012-9554-2 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23086656 ● Search Scopus @ Elsevier (PMID): 23086656 ● Search Scopus @ Elsevier (DOI): 10.1007/s10753-012-9554-2 (DOI: 10.1007/s10753-012-9554-2, PubMed: 23086656)
20.	Yuichi Nishiyama, Takahiro Kataoka, Junichi Teraoka, Akihiro Sakoda, Hiroshi Tanaka, Yuu Ishimori, Takehito Taguchi, Fumihiro Mitsunobu and Kiyonori Yamaoka : Suppression of streptozotocin-induced type-1 diabetes in mice by radon inhalation., Physiological Research / Academia Scientiarum Bohemoslovaca, Vol.62, No.1, 57-66, 2013. (Summary) We examined the protective effect of radon inhalation on streptozotocin (STZ)-induced type-1 diabetes in mice. Mice inhaled radon at concentrations of 1000, 2500, and 5500 Bq/m3 for 24 hours before STZ administration. STZ administration induced characteristics of type-1 diabetes such as hyperglycemia and hypoinsulinemia; however, radon inhalation at doses of 1000 and 5500 Bq/m3 significantly suppressed the elevation of blood glucose in diabetic mice. Serum insulin was significantly higher in mice pre-treated with radon at a dose of 1000 Bq/m3 than in mice treated with a sham. In addition, superoxide dismutase activities and total glutathione contents were significantly higher and lipid peroxide was significantly lower in mice pre-treated with radon at doses of 1000 and 5500 Bq/m3 than in mice treated with a sham. These results were consistent with the result that radon inhalation at 1000 and 5500 Bq/m3 suppressed hyperglycemia. These findings suggested that radon inhalation suppressed STZ-induced type-1 diabetes through the enhancement of antioxidative functions in the pancreas. (Keyword) Administration, Inhalation / Animals / Antioxidants / Biomarkers / Blood Glucose / Body Weight / Diabetes Mellitus, Experimental / Diabetes Mellitus, Type 1 / Dose-Response Relationship, Drug / Gases / Glutathione / Hypoglycemic Agents / Insulin / Male / Mice / Mice, Inbred C57BL / Pancreas / Radon / Streptozocin / Superoxide Dismutase / Time Factors (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23173687 ● Search Scopus @ Elsevier (PMID): 23173687 (PubMed: 23173687)
21.	Yuichi Nishiyama, Takahiro Kataoka, Keiko Yamato, Takehito Taguchi and Kiyonori Yamaoka : Suppression of dextran sulfate sodium-induced colitis in mice by radon inhalation., Mediators of Inflammation, Vol.2012, 2012. (Link to Publication Site) ● Publication site (DOI): 10.1155/2012/239617 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23365486 ● Search Scopus @ Elsevier (PMID): 23365486 ● Search Scopus @ Elsevier (DOI): 10.1155/2012/239617 (DOI: 10.1155/2012/239617, PubMed: 23365486)
22.	Teruaki Toyota, Takahiro Kataoka, Yuichi Nishiyama, Takehito Taguchi and Kiyonori Yamaoka : Inhibitory effects of pretreatment with radon on acute alcohol-induced hepatopathy in mice., Mediators of Inflammation, Vol.2012, 2012. (Keyword) Radon (Link to Publication Site) ● Publication site (DOI): 10.1155/2012/382801 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23213269 ● Search Scopus @ Elsevier (PMID): 23213269 ● Search Scopus @ Elsevier (DOI): 10.1155/2012/382801 (DOI: 10.1155/2012/382801, PubMed: 23213269)
23.	Keiko Yamato, Takahiro Kataoka, Yuichi Nishiyama, Takehito Taguchi and Kiyonori Yamaoka : Preventive and curative effects of radon inhalation on chronic constriction injury-induced neuropathic pain in mice., European Journal of Pain : EJP, Vol.17, No.4, 480-492, 2012. (Keyword) Administration, Inhalation / Animals / Behavior, Animal / Hyperalgesia / Mice / Neuralgia / Nitric Oxide / Norepinephrine / Pain Measurement / Physical Stimulation / Radon / Sciatic Neuropathy / Tumor Necrosis Factor-alpha (Link to Publication Site) ● Publication site (DOI): 10.1002/j.1532-2149.2012.00210.x (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22949231 ● Search Scopus @ Elsevier (PMID): 22949231 ● Search Scopus @ Elsevier (DOI): 10.1002/j.1532-2149.2012.00210.x (DOI: 10.1002/j.1532-2149.2012.00210.x, PubMed: 22949231)
24.	Takahiro Kataoka, Yuichi Nishiyama, Keiko Yamato, Junichi Teraoka, Yuji Morii, Akihiro Sakoda, Yuu Ishimori, Takehito Taguchi and Kiyonori Yamaoka : Comparative study on the inhibitory effects of antioxidant vitamins and radon on carbon tetrachloride-induced hepatopathy., Journal of Radiation Research, Vol.53, No.6, 830-839, 2012. (Link to Publication Site) ● Publication site (DOI): 10.1093/jrr/rrs057 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 23111757 ● Search Scopus @ Elsevier (PMID): 23111757 ● Search Scopus @ Elsevier (DOI): 10.1093/jrr/rrs057 (DOI: 10.1093/jrr/rrs057, PubMed: 23111757)
25.	Takahiro Kataoka, Junichi Teraoka, Akihiro Sakoda, Yuichi Nishiyama, Keiko Yamato, Mayuko Monden, Yuu Ishimori, Takaharu Nomura, Takehito Taguchi and Kiyonori Yamaoka : Protective effects of radon inhalation on carrageenan-induced inflammatory paw edema in mice., Inflammation, Vol.35, No.2, 713-722, 2012. (Keyword) Animals / Carrageenan / Catalase / Edema / Female / Inflammation / Lipid Peroxides / Mice / Mice, Inbred ICR / Nitric Oxide / Radon / Superoxide Dismutase / Tumor Necrosis Factor-alpha (Link to Publication Site) ● Publication site (DOI): 10.1007/s10753-011-9364-y (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21800149 ● Search Scopus @ Elsevier (PMID): 21800149 ● Search Scopus @ Elsevier (DOI): 10.1007/s10753-011-9364-y (DOI: 10.1007/s10753-011-9364-y, PubMed: 21800149)
26.	Yuichi Nishiyama, Takahiro Kataoka, Junichi Teraoka, Akihiro Sakoda, Yuu Ishimori and Kiyonori Yamoka : Inhibitory effects of pre and post radon inhalation on carbon tetrachloride-induced oxidative damage in mouse organs., Radioisotopes, Vol.61, No.5, 231-241, 2012. (Link to Publication Site) ● Publication site (DOI): 10.3769/radioisotopes.61.231 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.3769/radioisotopes.61.231 (DOI: 10.3769/radioisotopes.61.231)
27.	Takahiro Kataoka, Keiko Yamato, Yuichi Nishiyama, Yuji Morii, Reo Etani, Yuji Takata, Katsumi Hanamoto, Atsuishi Kawabe, Akihiro Sakoda, Yuu Ishimori, Takehito Taguchi and Kiyonori Yamaoka : Comparative study on the inhibitory effects of -tocopherol and radon on carbon tetrachloride-induced renal damage., Renal Failure, Vol.34, No.9, 1181-1187, 2012. (Keyword) Acute Kidney Injury / Animals / Antioxidants / Carbon Tetrachloride / Carbon Tetrachloride Poisoning / Disease Models, Animal / Female / Glomerular Filtration Rate / Kidney / Mice / Mice, Inbred ICR / Radon / Treatment Outcome / alpha-Tocopherol (Link to Publication Site) ● Publication site (DOI): 10.3109/0886022X.2012.717496 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22978362 ● Search Scopus @ Elsevier (PMID): 22978362 ● Search Scopus @ Elsevier (DOI): 10.3109/0886022X.2012.717496 (DOI: 10.3109/0886022X.2012.717496, PubMed: 22978362)
28.	Takahiro Kataoka, Yuichi Nishiyama, Teruaki Toyota, Masaaki Yoshimoto, Akihiro Sakoda, Yuu Ishimori, Yutaka Aoyama, Takehito Taguchi and Kiyonori Yamaoka : Radon inhalation protects mice from carbon-tetrachloride-induced hepatic and renal damage., Inflammation, Vol.34, No.6, 559-567, 2011. (Keyword) Animals / Antioxidants / Aspartate Aminotransferases / Carbon Tetrachloride / Chemical and Drug Induced Liver Injury / Glutathione / Glutathione Peroxidase / Inhalation / Kidney Diseases / Mice / Protective Agents / Radon (Link to Publication Site) ● Publication site (DOI): 10.1007/s10753-010-9263-7 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20890648 ● Search Scopus @ Elsevier (PMID): 20890648 ● Search Scopus @ Elsevier (DOI): 10.1007/s10753-010-9263-7 (DOI: 10.1007/s10753-010-9263-7, PubMed: 20890648)
29.	Takahiro Kataoka, Akihiro Sakoda, Masaaki Yoshimoto, Shinya Nakagawa, Teruaki Toyota, Yuichi Nishiyama, Keiko Yamato, Yuu Ishimori, Atsushi Kawabe, Katsumi Hanamoto, Takehito Taguchi and Kiyonori Yamaoka : Studies on possibility for alleviation of lifestyle diseases by low-dose irradiation or radon inhalation., Radiation Protection Dosimetry, Vol.146, No.1-3, 360-363, 2011. (Keyword) Administration, Inhalation / Animals / Antioxidants / Carbon Tetrachloride Poisoning / Chemical and Drug Induced Liver Injury / Edema / Liver / Liver Cirrhosis, Experimental / Male / Mice / Mice, Inbred BALB C / Oxidative Stress / Radon / Reperfusion Injury / Superoxide Dismutase / X-Ray Therapy (Link to Publication Site) ● Publication site (DOI): 10.1093/rpd/ncr189 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 21543347 ● Search Scopus @ Elsevier (PMID): 21543347 ● Search Scopus @ Elsevier (DOI): 10.1093/rpd/ncr189 (DOI: 10.1093/rpd/ncr189, PubMed: 21543347)
30.	Takahiro Kataoka, Akihiro Sakoda, Yuu Ishimori, Teruaki Toyota, Yuichi Nishiyama, Hiroshi Tanaka, Fumihiro Mitsunobu and Kiyonori Yamaoka : Study of the response of superoxide dismutase in mouse organs to radon using a new large-scale facility for exposing small animals to radon., Journal of Radiation Research, Vol.52, No.6, 775-781, 2011. (Keyword) Animals / Antioxidants / Dose-Response Relationship, Radiation / Male / Mice / Mice, Inbred BALB C / Organ Specificity / Radon / Superoxide Dismutase / Technology, Radiologic (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 22104270 ● Search Scopus @ Elsevier (PMID): 22104270 (PubMed: 22104270)
31.	Akihiro Sakoda, Yuichi Nishiyama, Katsumi Hanamoto, Yuu Ishimori, Yuki Yamamoto, Takahiro Kataoka, Atsushi Kawabe and Kiyonori Yamaoka : Differences of natural radioactivity and radon emanation fraction among constituent minerals of rock or soil., Applied Radiation and Isotopes, Vol.68, No.6, 1180-1184, 2010. (Link to Publication Site) ● Publication site (DOI): 10.1016/j.apradiso.2009.12.036 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 20117007 ● Search Scopus @ Elsevier (PMID): 20117007 ● Search Scopus @ Elsevier (DOI): 10.1016/j.apradiso.2009.12.036 (DOI: 10.1016/j.apradiso.2009.12.036, PubMed: 20117007)

Review, Commentary:

1.	Akinori Morita, Yuichi Nishiyama, Takuma Sakai and Yuichi Higashi : Molecular Mechanisms of Acute Radiation Intestinal Injury and Its Control, Radiation Environment and Medicine, Vol.13, No.1, 10-18, Feb. 2024. (Link to Publication Site) ● Publication site (DOI): 10.51083/radiatenvironmed.13.1_10 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390580936920512640 ● Search Scopus @ Elsevier (DOI): 10.51083/radiatenvironmed.13.1_10 (DOI: 10.51083/radiatenvironmed.13.1_10, CiNii: 1390580936920512640)
2.	Akinori Morita, Yuichi Nishiyama, Takuma Sakai and HIGASHI Yuichi : Molecular mechanisms of acute radiation intestinal injury and its control, 放射線生物研究 = Radiation biology research communications : 放射線生物研究会機関誌, Vol.58, No.2, 93-109, Jun. 2023. (Tokushima University Institutional Repository) ● Metadata: 118821 (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1050298588047514624 (Tokushima University Institutional Repository: 118821, CiNii: 1050298588047514624)
3.	Nobuyuki HAMADA, Toshioh FUJIBUCHI, Junya ISHIKAWA, Teruo ITO, Reo ETANI, Koji ONO, Yuichi Nishiyama and Kosuke MATSUBARA : Japanese Translation of NCRP Statement No. 13 "NCRP Recommendations for Ending Routine Gonadal Shielding During Abdominal and Pelvic Radiography" and Its Accompanying Documents National Council on Radiation Protection and Measurements, Japanese Journal of Health Physics, Vol.56, No.2, 80-93, 2021. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1390852259675906944 (CiNii: 1390852259675906944)
4.	Yuichi Nishiyama and Akinori Morita : Development of radioprotector based on the radiosensitivity modification by p53 regulation, Radiation Biology Research Communications, Vol.54, No.4, 237-250, Dec. 2019. (Link to Search Site for Scientific Articles) ● CiNii @ National Institute of Informatics (CRID): 1520009408701551744 (CiNii: 1520009408701551744)
5.	Shintaroh Ochi, Yuichi Nishiyama and Akinori Morita : Development of p53-targeting drugs that increase radioresistance in normal tissues., The Journal of Medical Investigation : JMI, Vol.66, No.3.4, 219-223, Aug. 2019. (Summary) Radiation damage to normal tissues is a serious concern in radiation therapy. Advances in radiotherapeutic technology have improved the dose distribution of the target volumes and risk organs, but damage to risk organs that are located within the irradiation field still limits the allowable prescription dose. To overcome this dose-limiting toxicity, and to further improve the efficacy of radiotherapy, the development of drugs that protect normal tissues but not cancer tissues from the effects of radiation are expected to be developed based on molecular target-based drugs. p53 is a well-known transcription factor that is closely associated with radiation-induced cell death. In radiation-injured tissues, p53 induces apoptosis in hematopoietic lineages, whereas it plays a radioprotective role in the gastrointestinal epithelium. These facts suggest that p53 inhibitor would be effective for radioprotection of the hematopoietic system, and that a drug that upregulates the radioprotective functions of p53 would enhance the radioresistance of gastrointestinal tissues. In this review, we summarize recent progress regarding the prevention of radiation injury by regulating p53 and provide new strategic insights into the development of radioprotectors in radiotherapy. J. Med. Invest. 66 : 219-223, August, 2019. (Tokushima University Institutional Repository) ● Metadata: 114026 (Link to Publication Site) ● Publication site (DOI): 10.2152/jmi.66.219 (Link to Search Site for Scientific Articles) ● PubMed @ National Institutes of Health, US National Library of Medicine (PMID): 31656277 ● Search Scopus @ Elsevier (PMID): 31656277 ● Search Scopus @ Elsevier (DOI): 10.2152/jmi.66.219 (Tokushima University Institutional Repository: 114026, DOI: 10.2152/jmi.66.219, PubMed: 31656277)
6.	Yuichi Nishiyama, 竹下治男 and 北垣一 : 脳CT画像における死後変化と最近の研究動向, 日本診療放射線技師会雑誌, Vol.65, No.789, 12-15, 2018.
7.	迫田晃弘, 片岡憲昭, 石川純也, 太田朗生, 鈴木龍彦, Yuichi Nishiyama, 廣内淳 and 外間智規 : Report on special sessions in the 49th Annual Meeting of the Japan Health Physics Society, 保健物理, Vol.51, No.3, 181-186, 2016.
8.	Yuichi Nishiyama, 片岡隆浩 and 山岡聖典 : Study on Health Effects of Exposure to Radon : Recent Studies on Effects and Mechanisms of Radon Therapy., Transactions of the Atomic Energy Society of Japan, Vol.12, No.4, 267-276, 2013. (Link to Publication Site) ● Publication site (DOI): 10.3327/taesj.J13.004 (Link to Search Site for Scientific Articles) ● Search Scopus @ Elsevier (DOI): 10.3327/taesj.J13.004 (DOI: 10.3327/taesj.J13.004)
9.	大和恵子, 片岡隆浩, Yuichi Nishiyama and 山岡聖典 : Recent Studies on Antinociceptive Effects of Radon Therapy for Pain-related Diseases, Radiation Biology Research Communications, Vol.48, No.1, 66-81, 2013.

Proceeding of International Conference:

1.	Sonoyama Yuichiro, Yuichi Nishiyama, Akinori Morita, Wang Bing, Sawatani Megumi, Shimokawa Takashi and Aoki Shin : Protective effect of sodium orthovanadate against radiation-induced male infertility in mice, The 8th International Symposium of the Network-type Joint Usage/ Research Center for Radiation Disaster Medical Science, Nagasaki, Feb. 2024.
2.	Takuma Sakai, Akinori Morita, Akinori Kanai, Bing Wang, Atsushi Enomoto, Shohei Ujita, Shin Aoki, Hidetoshi Satoh, Ryoya Kawabata, Masahiro Sakaue, Yuichi Nishiyama and Toshiya Inaba : A comprehensive analysis of the effects of 5CHQ on the radiation-injured intestinal epithelium, The 4th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science, Hiroshima, Feb. 2020.
3.	Yuichi Nishiyama, Akinori Morita, Wang Bing, Tanaka Kaoru, Katsube Takanori, Murakami Masahiro, Ochi Shintaro, Teraoka Tatsuro, Dwindling Ramadhani, Shimokawa Takashi, Neon Mitsuru and Aoki Shin : Protective effects of p53-regulating agents against high-LET radiation-induced injury in mice., 2nd Technological Competency as Caring in the Health Sciences 2018, Tokushima, Aug. 2018.
4.	Yuichi Nishiyama, Hiroshi Mori, Keiji Tada, Hidekazu Kanayama, Yasushi Yamamoto, Kazunori Kawakami, Takashi Katsube, Haruo Takeshita and Hajime Kitagaki : Characteristic CT value changes in postmortem brain analyzed by statistical parametric mapping, Radiological Society of North America 2016, Nov. 2016.
5.	Takahiro Kataoka, Yuichi Nishiyama, Keiko Yamato, Reo Etani, Yuji Takata and Kiyonori Yamaoka : Our recent studies on activation of antioxidant system by radon inhalation and its applicable possibility for treatment of inflammation and pain, 17th Biennial Meeting of Society for Free Radical Research International, Mar. 2014.
6.	Takahiro Kataoka, Yuichi Nishiyama, Akihiro Sakoda, HIroshi Tanaka, Atsushi Kawabe, Katsumi Hanamoto, Yuu Ishimori, Takehito Taguchi, Fumihiro Mitsunobu and Kiyonori Yamaoka : Studies on effects of radon inhalation on oxidative damage in mice using a new facility for exposing small animals to radon, 3rd Asian Congress of Radiation Research, May 2013.
7.	Takahiro Kataoka, Masaaki Yoshimoto, Yuichi Nishiyama, Junnichi Teraoka, Keiko Yamato, Akihiro Sakoda, Takehito Taguchi and Kiyonori Yamaoka : Recent studies on possibility for alleviation of oxidative damage and inflammation by low-dose irradiation, 5th Biennial Meeting of Society for Free Radical Research-Asia, Aug. 2011.
8.	Yuichi Nishiyama, Takahiro Kataoka, Junnichi Teraoka, Akihiro Sakoda, Keiko Yamato, Yuu Ishimori and Kiyonori Yamaoka : A comparative study on effect of prior or post radon inhalation on carbon tetrachloride induced oxidative damage in some organs of mouse, 5th Biennial Meeting of Society for Free Radical Research-Asia, Aug. 2011.
9.	Takahiro Kataoka, Akihiro Sakoda, Masaaki Yoshimoto, Shinya Nakagawa, Teruaki Toyota, Yuichi Nishiyama, Yuu Ishimori, Atsushi Kawabe, Katsumi Hanamoto, Takehito Taguchi and Kiyonori Yamaoka : Studies on possibility for alleviation of lifestyle diseases by low-dose irradiation or radon inhalation, The 3rd Asian and Oceanic Congress on Radiation Protection, May 2010.
10.	Akihiro Sakoda, Katsumi Hanamoto, Yuu Ishimori, Atsushi Kawabe, Takahiro Kataoka, Yuki Yamamoto, Yuichi Nishiyama and Kiyonori Yamaoka : Study of fundamental physical properties of mineral grains toward understanding radon emanation phenomenon, The 3rd Asian and Oceanic Congress on Radiation Protection, May 2010.

Proceeding of Domestic Conference:

1.	シャラミラゴシュ, Akinori Morita, Yuichi Nishiyama, SAKAUE Masahiro, Daiki Morita, Ken Fujiwara, HIGASHI Yuichi and SONOYAMA Yuichiroh : 急性放射線性直腸障害における直腸上皮幹細胞動態, 第32回日本Cell Death学会学術集会, Jul. 2024.
2.	Yuichi Nishiyama, SONOYAMA Yuichiroh, Akinori Morita, 王冰, 笹谷めぐみ, 下川卓志 and 青木伸 : p53制御剤バナデートの放射線被ばくに対する雄性生殖能力保護効果, 第61回日本放射線腫瘍学会生物部会学術大会, May 2024.
3.	西山由佳子, 薮内健治, Yuichi Nishiyama, 神原康夫, 生島葉子 and 江西哲也 : 体幹部造影CT検査における上肢交差挙上位による造影剤フローの改善, 第80回⽇本放射線技術学会総会学術⼤会, Apr. 2024.
4.	GHOSH Sharmila, Akinori Morita, Yuichi Nishiyama, HIGASHI Yuichi and YUICHIROH Sonoyama : Rectal epithelial stem cell kinetics in acute radiation enteritis, ⽇本放射線影響学会第66回⼤会, Nov. 2023.
5.	YUICHIROH Sonoyama, Yuichi Nishiyama, Akinori Morita, 王冰, 笹谷めぐみ, 下川卓志 and 青木伸 : Sodium orthovanadate protects male fertility against radiation exposure, ⽇本放射線影響学会第66回⼤会, Nov. 2023.
6.	Akinori Morita, TANIMOTO Taiga, HIGASHI Yuichi, Yuichi Nishiyama, SHOJI Tsugumi, 村田貴嗣, 小向杏佳, 金井昭教, Taisei Kunii, Takuma Sakai, Ryo Sadatomi, 王冰, 下川卓志, 中田健也, 武村直紀, Tatsuya Saitoh, 稲葉俊哉 and 椎名勇 : 炎症誘発性プラットフォームを標的とする放射線防護剤の開発, 第60回日本放射線腫瘍学会生物部会学術大会, Jun. 2023.
7.	YUICHIROH Sonoyama, Yuichi Nishiyama, Akinori Morita, 王冰, 佐藤秀哉 and 青木伸 : p53制御剤による放射線被ばくに対する雄性妊孕性温存, 第59回日本放射線腫瘍学会生物部会学術大会, Jun. 2022.
8.	Taiga Tanimoto, Akinori Morita, Yuichi Nishiyama, Takatsugu Murata, Anjyu Sakai, Akinori Kanai, Yuichi Higashi, Taisei Kunii, Takuma Sakai, Ryo Sadatomi, Bing Wang, Takashi Shimokawa, Kenya Nakata, Naoki Takemura, Tatsuya Saitoh, Toshiya Inaba and Isamu Shiina : A novel immunomodulatory compound that prevents sub-total body irradiation-induced intestinal death, The 64th Annual Meeting of the Japan Radiation Research Society, Sep. 2021.
9.	HIGASHI Yuichi, Akinori Morita, Yuichi Nishiyama, 村田貴嗣, 酒井杏樹, 金井昭教, TANIMOTO Taiga, Takuma Sakai, 中田健也, 武村直紀, Tatsuya Saitoh, 稲葉俊哉 and 椎名勇 : 抗炎症作用を有する新規化合物の腸炎制御剤としての活性評価, 第29回日本Cell Death学会学術集会, Jul. 2021.
10.	Akinori Morita, 王冰, 田中薫, 勝部孝則, 村上正弘, 下川卓志, Yuichi Nishiyama, Shintaroh Ochi, 佐藤秀哉, 根井充 and 青木伸 : p53を標的とした放射線防護剤の粒子線治療における役割, 第58回生物部会学術大会・第49回放射線による制癌シンポジウム, Jun. 2021.
11.	TANIMOTO Taiga, Akinori Morita, Yuichi Nishiyama, 村田貴嗣, 酒井杏樹, 金井昭教, HIGASHI Yuichi, Shintaroh Ochi, Taisei Kunii, Takuma Sakai, Ryo Sadatomi, 王冰, 下川卓志, 中田健也, Tatsuya Saitoh, 稲葉俊哉 and 椎名勇 : 抗炎症作用を有する新規化合物の放射線防護剤としての活性評価, 第58回生物部会学術大会・第49回放射線による制癌シンポジウム, Jun. 2021.
12.	Akinori Morita, Tatsuta Shogo, Sakaue Masahiro, Fujita Ria, Hanaya Kengo, Sugai Takeshi, Yuichi Nishiyama, Ochi Shintaro, Sakai Takuma, Wang Bing and Aoki Shin : Evaluation of the radioprotective effects of flavonoids., The 62th Annual Meeting of the Japan Radiation Research Society, Nov. 2019.
13.	Yuichi Nishiyama, Akinori Morita, Wang Bing, Sakai Takuma, Ramadhani Dwi, Satoh Hidetoshi, Kawabata Ryoya, Tanaka Kaoru, Sasatani Megumi, Ochi Shintaro, Nenoi Mitsuru and Aoki Shin : The p53 inhibitor sodium orthovanadate is not effective in relieving acute gastrointestinal syndrome of subtotal-body irradiated mice., The 62th Annual Meeting of the Japan Radiation Research Society, Nov. 2019.
14.	Sakai Takuma, Akinori Morita, Kanai Akinori, Wang Bing, Enomoto Atsushi, Ujita Shohei, Aoki Shin, Sato HIdetoshi, Kawabata Junya, Sakaue Masahito, Yuichi Nishiyama and Inaba Toshiya : The radioprotector 5CHQ upregulates gene expression of radioprotective humoral factors in acute radiation-injured murine intestinal epithelium., The 62th Annual Meeting of the Japan Radiation Research Society, Nov. 2019.
15.	Akinori Morita, 王冰, 田中薫, 勝部孝則, 村上正弘, Yuichi Nishiyama, Shintaroh Ochi, 寺岡達朗, 佐藤秀哉, 川端凌矢, 下川卓志, 根井充 and 青木伸 : p53制御による重粒子放射線防護効果, 第57回日本放射線腫瘍学会生物部会学術大会, Jun. 2019.
16.	Takuma Sakai, Yuichi Nishiyama, Akinori Morita, 王冰, ラマダニードゥウィー, 佐藤秀哉, 川端凌矢, 田中薫, 笹谷めぐみ, Shintaroh Ochi, 根井充 and 青木伸 : p53阻害剤バナデートは亜全身照射後のマウス腸管障害を促進する, 第57回日本放射線腫瘍学会生物部会学術大会,弘前, Jun. 2019.
17.	Takuma Sakai, Shohei Ujita, 榎本敦, Yohsuke Kawate, Yuichi Nishiyama, 寺岡達朗, 青木伸, 王冰, 金井昭教, 稲葉俊哉 and Akinori Morita : 放射線防護剤5CHQの遺伝子発現調節作用の網羅的解析, 日本放射線影響学会第61回大会, Nov. 2018.
18.	Yuichi Nishiyama, Taisei Kunii, 笹谷めぐみ, 寺岡達朗, Takuma Sakai, Yuichi Nishiyama, 神谷研二, 王冰, 青木伸 and Akinori Morita : p53調節剤5CHQの類縁体探索から見出された5QXの放射線防護活性評価, 日本放射線影響学会第61回大会, Nov. 2018.
19.	Akinori Morita, 王冰, 田中薫, 勝部孝則, 村上正弘, Yuichi Nishiyama, Shintaroh Ochi, 寺岡達朗, ラマダニードゥウィー, 下川卓志, 根井充 and 青木伸 : p53制御剤による重粒子放射線防護効果, 日本放射線影響学会第61回大会, Nov. 2018.
20.	Akinori Morita, 王冰, 田中薫, 勝部孝則, 村上正弘, ラマダニードゥウィー, 下川卓志, 根井充, Shintaroh Ochi, Yuichi Nishiyama, 寺岡達朗 and 青木伸 : 細胞死制御剤による重粒子放射線防護効果, 第56回日本放射線腫瘍学会生物部会学術大会, Jul. 2018.
21.	Yuichi Nishiyama, 西山由佳子, 多田圭司, 森博史, 丸山光成, 勝部敬, 山本伸子, 金山秀和, 山本泰司 and 北垣一 : 順投影適用モデルベース逐次近似再構成を用いた小児心臓CT検査における被曝低減の可能性, 日本保健物理学会第50回研究発表会, Jun. 2017.
22.	Yuichi Nishiyama, 金山秀和, 森博史, 多田圭司, 山本泰司, 勝部敬, 竹下治男 and 北垣一 : 頭部Ai-CT画像における死後変化の性差に関する検討, 第12回中四国放射線医療技術フォーラム, Nov. 2016.
23.	Hiroshi Mori, Yuichi Nishiyama, Keiji Tada, Hidekazu Kanayama, Yasushi Yamamoto, Takashi Katsube, Haruo Takeshita and Hajime Kitagaki : Analyses of postmortem brain CT changes by using statistical parametric mapping, 第75回日本医学放射線学会総会, Apr. 2016.
24.	Yuichi Nishiyama, Keiji Tada, Hidekazu Kanayama, Yasushi Yamamoto, Takashi Katsube, Haruo Takeshita and Hajime Kiatagaki : The analysis of postmortem changes in brain computed tomography using statistical parametric mapping, 第72回日本放射線技術学会総会学術大会, Apr. 2016.
25.	Yuichi Nishiyama, 大和恵子, 花房直志 and 小野俊朗 : ヒドロキシアパタイトによる放射性ストロンチウムの除去法の開発, 日本放射線安全管理学会第13回学術大会, Dec. 2014.
26.	片岡隆浩, Yuichi Nishiyama, 迫田晃弘, 恵谷玲央, 神崎訓枝, 田中裕史, 石森有, 光延文裕 and 山岡聖典 : ラドン含有の吸入と飲泉によるマウス1型糖尿病の抑制効果の比較検討, 日本放射線影響学会第57回大会, Oct. 2014.
27.	恵谷玲央, 片岡隆浩, Yuichi Nishiyama, 迫田晃弘, 神崎訓枝, 田中裕史, 石森有, 光延文裕, 田口勇仁 and 山岡聖典 : ラドン吸入によるマウス腎障害の抑制効果における抗酸化機能の関与の検討, 日本放射線影響学会第57回大会, Oct. 2014.
28.	片岡隆浩, 高田裕司, 恵谷玲央, Yuichi Nishiyama, 川辺睦, 花元克己, 神崎訓枝, 中田哲也, 田口勇仁 and 山岡聖典 : 極微量放射性物質塗布によるマウス炎症性浮腫の抑制効果, 第67回日本酸化ストレス学会学術集会, Sep. 2014.
29.	恵谷玲央, 片岡隆浩, Yuichi Nishiyama, 迫田晃弘, 神崎訓枝, 田中裕史, 石森有, 光延文裕, 田口勇仁 and 山岡聖典 : マウス腎臓におけるラドン吸入による抗酸化機能の亢進と関連疾患抑制の検討, 第67回日本酸化ストレス学会学術集会, Sep. 2014.
30.	山岡聖典, 片岡隆浩, Yuichi Nishiyama, 恵谷玲央, 神崎訓枝, 光延文裕, 石森有, 迫田晃弘 and 田中裕史 : ラドン温泉において糖尿病の抑制に吸入と飲泉はどちらが有効か, 第67回日本酸化ストレス学会学術集会, Sep. 2014.
31.	恵谷玲央, 片岡隆浩, Yuichi Nishiyama, 高田裕司 and 山岡聖典 : ラドン吸入と抗酸化ビタミン投与の併用によるアルコール性マウス肝障害の抑制効果に関する検討, 日本原子力学会中国・四国支部第8回研究発表会, Sep. 2014.
32.	恵谷玲央, 片岡隆浩, 高田裕司, Yuichi Nishiyama, 迫田晃弘, 石森有, 光延文裕, 田口勇仁 and 山岡聖典 : ラドン吸入によるマウス腎障害の抑制効果とその医療応用の可能性, 第51回アイソトープ・放射線研究発表会, Jul. 2014.
33.	片岡隆浩, Yuichi Nishiyama, 迫田晃弘, 恵谷玲央, 神崎訓枝, 田中裕史, 石森有, 光延文裕 and 山岡聖典 : ラドン含有の吸入または飲泉がマウス糖尿病に及ぼす効果, 平成26年度京都大学原子炉実験所専門研究会, Jul. 2014.
34.	片岡隆浩, 恵谷玲央, Yuichi Nishiyama, 高田裕司, 田口勇仁 and 山岡聖典 : 低線量放射線の健康影響研究:ラドン吸入による一過性脳虚血に伴う細胞障害の抑制効果, 日本原子力学会2014年春の年会, Mar. 2014.
35.	片岡隆浩, Yuichi Nishiyama, 恵谷玲央, 高田裕司, 迫田晃弘, 石森有, 光延文裕, 田口勇仁 and 山岡聖典 : ラドン吸入によるマウス肝障害の抑制効果とその医療応用の可能性, 日本放射線影響学会第56回大会, Oct. 2013.
36.	Yuichi Nishiyama, 片岡隆浩, 恵谷玲央, 大和恵子, 高田裕司, 田口勇仁 and 山岡聖典 : ラドン吸入によるマウス炎症性腸疾患の症状緩和に関する検討, 日本放射線影響学会第56回大会, Oct. 2013.
37.	迫田晃弘, 石森有, 田中裕史, 山岡聖典, 片岡隆浩, Yuichi Nishiyama and 光延文裕 : ラドン雰囲気におけるマウスの臓器吸収線量の系統的検討, 日本放射線影響学会第56回大会, Oct. 2013.
38.	片岡隆浩, Yuichi Nishiyama, 恵谷玲央, 高田裕司, 迫田晃弘, 石森有, 田口勇仁 and 山岡聖典 : マウスへのラドン吸入と抗酸化ビタミン投与による抗酸化作用の比較検討, 日本原子力学会中国・四国支部第7回研究発表会, Sep. 2013.
39.	Yuichi Nishiyama, 片岡隆浩, 大和恵子, 田口勇仁 and 山岡聖典 : ラドン吸入によるマウス大腸炎の抑制効果に関する検討, 第50回アイソトープ・放射線研究発表会, Jul. 2013.
40.	恵谷玲央, 片岡隆浩, Yuichi Nishiyama, 大和恵子, 高田裕司 and 山岡聖典 : ラドン吸入と抗酸化ビタミン投与によるマウス肝障害の抑制の相乗効果に関する検討, 第50回アイソトープ・放射線研究発表会, Jul. 2013.
41.	高田裕司, 片岡隆浩, 恵谷玲央, Yuichi Nishiyama, 大和恵子, 田口勇仁 and 山岡聖典 : 極微量放射性クリームがマウス炎症性足浮腫に及ぼす効果に関する検討, 第50回アイソトープ・放射線研究発表会, Jul. 2013.
42.	迫田晃弘, 石森有, 田中裕史, 山岡聖典, 片岡隆浩, Yuichi Nishiyama and 光延文裕 : 三朝医療センターラドン吸入試験におけるマウスの線量評価, 第46回日本保健物理学会研究発表会, Jun. 2013.
43.	Yuichi Nishiyama, 片岡隆浩, 大和恵子, 田口勇仁 and 山岡聖典 : ラドン吸入によるマウス炎症性腸疾患の抑制効果に関する検討, 第66回日本酸化ストレス学会学術集会, Jun. 2013.
44.	片岡隆浩, Yuichi Nishiyama, 恵谷玲央, 高田裕司, 豊田晃章, 迫田晃弘, 石森有, 光延文裕, 田口勇仁 and 山岡聖典 : ラドン吸入によるCCl4誘導マウス肝障害の抑制効果とその医療応用の可能性, Jun. 2013.
45.	豊田晃章, 片岡隆浩, Yuichi Nishiyama, 田口勇仁 and 山岡聖典 : ラドン吸入による急性アルコール性マウス肝障害の抑制効果に関する検討, 第66回日本酸化ストレス学会学術集会, Jun. 2013.
46.	Yuichi Nishiyama, 片岡隆浩, 迫田晃弘, 大和恵子, 田中裕史, 石森有, 光延文裕, 田口勇仁 and 山岡聖典 : ラドン療法によるⅠ型糖尿病の症状緩和に関する一考察, 日本放射線影響学会第55回大会, Sep. 2012.
47.	片岡隆浩, Yuichi Nishiyama, 迫田晃弘, 大和恵子, 森井佑至, 恵谷玲央, 高田裕司, 石森有, 田口勇仁 and 山岡聖典 : マウス肝臓・腎臓におけるラドン吸入による抗酸化機能亢進とビタミン作用との比較, 日本放射線影響学会第55回大会, Sep. 2012.
48.	大和恵子, 片岡隆浩, Yuichi Nishiyama, 花元克巳, 川辺睦, 田口勇仁 and 山岡聖典 : ラドン吸入によるマウス神経障害性疼痛の予防と緩和の効果に関する検討, 日本放射線影響学会第55回大会, Sep. 2012.
49.	Yuichi Nishiyama, 片岡隆浩, 大和恵子, 迫田晃弘, 田中裕史, 石森有, 光延文裕, 田口勇仁 and 山岡聖典 : ラドン吸入によるⅠ型糖尿病マウスの抑制効果に関する検討, 第49回アイソトープ・放射線研究発表会, Jul. 2012.
50.	大和恵子, 片岡隆浩, Yuichi Nishiyama, 田口勇仁 and 山岡聖典 : ラドン吸入による炎症性疼痛と神経障害性疼痛の緩和効果に関する検討, 第49回アイソトープ・放射線研究発表会, Jul. 2012.
51.	森井佑至, 片岡隆浩, Yuichi Nishiyama, 迫田晃弘, 大和恵子, 恵谷玲央, 高田裕司, 石森有, 田口勇仁 and 山岡聖典 : マウス肝障害に対するラドン吸入とビタミンC・E投与による各抗酸化作用の比較検討, 第49回アイソトープ・放射線研究発表会, Jul. 2012.
52.	片岡隆浩, Yuichi Nishiyama, 迫田晃弘, 大和恵子, 恵谷玲央, 高田裕司, 森井佑至, 石森有, 田口勇仁 and 山岡聖典 : 極微量ウラン子孫核種の吸入による抗酸化機能の亢進に関するビタミン投与との比較による定量化, 第65回日本酸化ストレス学会学術集会, Jun. 2012.
53.	Yuichi Nishiyama, 片岡隆浩, 迫田晃弘, 田中裕史, 石森有, 田口勇仁, 光延文裕 and 山岡聖典 : ラドン吸入によるストレプトゾトシン誘導マウス1型糖尿病の抑制効果に関する検討, 第65回日本酸化ストレス学会学術集会, Jun. 2012.
54.	Yuichi Nishiyama, 片岡隆浩, 寺岡准一, 迫田晃弘, 大和恵子, 石森有 and 山岡聖典 : 四塩化炭素誘導マウス臓器障害に対するラドンの事前と事後吸入の抑制効果の比較検討, 日本放射線影響学会第54回大会, Nov. 2011.
55.	片岡隆浩, 寺岡准一, Yuichi Nishiyama, 迫田晃弘, 大和恵子, 石森有, 野村崇治, 田口勇仁 and 山岡聖典 : ラドン吸入によるカラゲニン誘導マウス炎症性足浮腫の抑制効果に関する検討, 日本放射線影響学会第54回大会, Nov. 2011.
56.	大和恵子, 片岡隆浩, Yuichi Nishiyama, 寺岡准一, 森井佑至, 田口勇仁 and 山岡聖典 : ラドン吸入によるマウス炎症性疼痛の緩和効果に関する検討, 日本放射線影響学会第54回大会, Nov. 2011.
57.	寺岡准一, 片岡隆浩, Yuichi Nishiyama, 森井佑至, 大和恵子, 迫田晃弘, 石森有, 田口勇仁 and 山岡聖典 : 四塩化炭素誘導マウス肝障害に対するラドンとアスコルビン酸の各抗酸化作用の比較検討, 日本放射線影響学会第54回大会, Nov. 2011.
58.	片岡隆浩, 寺岡准一, 迫田晃弘, Yuichi Nishiyama, 大和恵子, 野村崇治, 石森有, 田口勇仁 and 山岡聖典 : ラドン吸入装置の開発とこれを用いたマウスカラゲニン誘導浮腫の抑制効果に関する検討, 第64回日本酸化ストレス学会学術集会, Jul. 2011.
59.	片岡隆浩, 迫田晃弘, 吉本雅章, Yuichi Nishiyama, 大和恵子, 寺岡准一, 豊田晃章, 石森有, 田口勇仁 and 山岡聖典 : ラドン吸入によるマウスの抗酸化機能亢進と疾患抑制効果に関する最近の研究動向, 第48回アイソトープ・放射線研究発表会, Jul. 2011.
60.	Yuichi Nishiyama, 迫田晃弘, 石森有, 片岡隆浩, 光延文裕 and 山岡聖典 : 岡山大学病院(三朝)におけるラドン療法用の温泉水中，および周辺空間中ラドン濃度の特性, 日本放射線安全管理学会第9回学術大会, Dec. 2010.
61.	片岡隆浩, 迫田晃弘, 石森有, 豊田晃章, Yuichi Nishiyama, 花元克巳, 川辺睦, 田中裕史, 光延文裕 and 山岡聖典 : ラドン吸入に対するマウス臓器別感受性に関する検討, 日本放射線影響学会第53回大会, Oct. 2010.
62.	Yuichi Nishiyama, 片岡隆浩, 迫田晃弘, 豊田晃章, 寺岡准一, 青山裕, 花元克巳, 川辺睦, 田口勇仁 and 山岡聖典 : ラドン吸入による四塩化炭素誘導マウス腎障害の抑制に関する検討, 日本放射線影響学会第53回大会, Oct. 2010.
63.	迫田晃弘, 花元克巳, 片岡隆浩, 川辺睦, 吉本雅章, 豊田晃章, Yuichi Nishiyama, 寺岡准一, 深尾光佑 and 山岡聖典 : 小動物用ラドン吸入装置の開発とその性能評価, 日本放射線影響学会第53回大会, Oct. 2010.
64.	迫田晃弘, 深尾光佑, 石森有, 花元克巳, 川辺睦, 片岡隆浩, Yuichi Nishiyama and 山岡聖典 : ラドン子孫核種の吸入線量評価に向けたマウス肺気道における粒子の沈着効率の解析, 日本放射線影響学会第53回大会, Oct. 2010.
65.	片岡隆浩, 迫田晃弘, 石森有, 豊田晃章, Yuichi Nishiyama, 田中裕史, 光延文裕 and 山岡聖典 : ラドン吸入による抗酸化機能亢進のマウス臓器別感受性に関する検討, 第63回日本酸化ストレス学会, Jun. 2010.
66.	吉本雅章, 片岡隆浩, 中川慎也, 豊田晃章, Yuichi Nishiyama, 田口勇仁 and 山岡聖典 : 低線量X線照射による凍結マウス脳損傷の抑制効果の病理学的検討, 日本放射線影響学会第52回大会, Nov. 2009.
67.	豊田晃章, 片岡隆浩, Yuichi Nishiyama, 吉本雅章, 田口勇仁 and 山岡聖典 : 低線量X線照射によるマウス慢性アルコール障害の抑制効果の検討, 日本放射線影響学会第52回大会, Nov. 2009.
68.	迫田晃弘, 花元克巳, 石森有, 山本祐紀, Yuichi Nishiyama and 山岡聖典 : 岩石における自然放射能分布の不均一性の検討, 日本放射線影響学会第52回大会, Nov. 2009.
69.	花元克巳, 迫田晃弘, 山本祐紀, Yuichi Nishiyama, 石森有, 永松知洋 and 山岡聖典 : バドガスタイン産出岩石から分離した鉱石中の放射能特性, 日本放射線影響学会第51回大会, Nov. 2008.
70.	片岡隆浩, 迫田晃弘, 野村崇治, 石森有, 豊田晃章, Yuichi Nishiyama, 吉本雅章, 光延文裕, 田口勇仁 and 山岡聖典 : ラドン吸入による四塩化炭素誘導マウス肝障害の抑制効果とその最適吸入条件の検討, 日本放射線影響学会第51回大会, Nov. 2008.

Et cetera, Workshop:

1.	Yuichi Nishiyama and Akinori Morita : 放射線のはたらきを最適化するp53制御性放射線防護剤の開発, 日本原子力学会中国・四国支部講演会, Jun. 2022.
2.	Yuichi Nishiyama : 死後脳CT画像における死後変化の全脳解析, 低線量放射線健康影響研究会2017, Sep. 2017.
3.	片岡隆浩, 神﨑訓枝, Yuichi Nishiyama, 大和恵子, 花元克巳 and 山岡聖典 : ラドン吸入による炎症・疼痛の緩和効果に関する我々の研究動向, 低線量放射線健康影響研究会2016, Sep. 2016.
4.	片岡隆浩, 恵谷玲央, Yuichi Nishiyama, 高田裕司, 田口勇仁 and 山岡聖典 : ラドン吸入によるスナネズミ一過性脳虚血に伴う細胞障害の抑制効果に関する検討, 文部科学省復興対策特別人材育成事業「被ばくの瞬間から生涯」を見渡す放射線生物・医学の学際教育第3回集中講義, Jan. 2014.
5.	高田裕司, 片岡隆浩, 恵谷玲央, Yuichi Nishiyama, 大和恵子, 田口勇仁 and 山岡聖典 : マウス炎症症状に対する極微量放射性クリームの抑制効果に関する検討, 文部科学省復興対策特別人材育成事業「被ばくの瞬間から生涯」を見渡す放射線生物・医学の学際教育第3回集中講義, Jan. 2014.
6.	恵谷玲央, 片岡隆浩, Yuichi Nishiyama, 高田裕司 and 山岡聖典 : ラドン吸入と抗酸化ビタミン投与の併用による急性アルコール性マウス肝障害の抑制効果に関する検討, 文部科学省復興対策特別人材育成事業「被ばくの瞬間から生涯」を見渡す放射線生物・医学の学際教育第3回集中講義, Jan. 2014.
7.	片岡隆浩, Yuichi Nishiyama, 大和恵子, 森井佑至, 恵谷玲央, 高田裕司, 迫田晃弘, 石森有, 光延文裕, 田口勇仁 and 山岡聖典 : ラドン健康効果に関する最近の我々の研究動向, 平成24年度京都大学原子炉実験所専門研究会, Aug. 2012.
8.	Yuichi Nishiyama, 片岡隆浩, 迫田晃弘, 田中裕史, 石森有, 光延文裕, 田口勇仁 and 山岡聖典 : ラドン吸入によるマウスⅠ型糖尿病の抑制効果の検討, Aug. 2012.
9.	恵谷玲央, 片岡隆浩, 森井佑至, Yuichi Nishiyama, 大和恵子, 高田裕司, 迫田晃弘, 石森有, 田口勇仁 and 山岡聖典 : マウス肝障害に対するラドン吸入とビタミンC・E投与による抗酸化作用の比較検討, 平成24年度京都大学原子炉実験所専門研究会, Aug. 2012.

Report:

1.	石森有, 迫田晃弘, 田中裕史, 光延文裕, 山岡聖典, 片岡隆浩, 大和恵子 and Yuichi Nishiyama : 極微量ウラン影響効果試験, JAEA-Research, Vol.005, 2013.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

Mechanism of action of sodium orthovanadate to inhibit radiation-induced male infertility (Project/Area Number: 24K10762 )
A novel radioprotective mechanism of sodium orthovanadate and its application to radiotherapy (Project/Area Number: 21K07644 )
Development of p53 regulators increasing radioresistance of the intestinal tissue (Project/Area Number: 19K17143 )
Functional changes of postmortem brain and its effects on MRI image ocntrast (Project/Area Number: 17K17891 )
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Assistant Professor : Nishiyama, Yuichi

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Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)