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Tokushima University ⟩ Graduate School of Biomedical Sciences ⟩ 歯学域 ⟩ 先端歯学教育研究プロジェクト ⟩
Tokushima University ⟩ Graduate School of Biomedical Sciences ⟩ 歯学域 ⟩ Oral Science ⟩ Clinical Dentistry ⟩ Department of Orthodontics and Dentofacial Orthopedics ⟩
Tokushima University ⟩ University Hospital ⟩ Clinical Division ⟩ Department of Orthodontics ⟩
Tokushima University ⟩ Faculty of Dentistry ⟩ Course in Dentistry ⟩ Clinical Dentistry for Promotion and Development ⟩ Orthodontics and Dentofacial Orthodontics ⟩ 		(Files for researchmap) [PDF manual] [Auto-propagate to researchmap]

Research

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Book / Paper

Academic Paper (Judged Full Paper):

1. Kimiko Sogabe, Shingen Nakamura, Yoshiki Higa, Hirokazu Miki, Asuka Oda, Tomoko Maruhashi, Ryohei Sumitani, Masahiro Oura, Mamiko Takahashi, Masafumi Nakamura, Yusaku Maeda, Tomoyo Hara, Hiroki Yamagami, Shiroh Fujii, Kumiko Kagawa, Shuji Ozaki, Kiyoe Kurahashi, Itsuro Endo, Ken-ichi Aihara, Emiko Nakaue, Masahiro Hiasa, Jumpei Teramachi, Takeshi Harada and Masahiro Abe :
Acute accumulation of PIM2 and NRF2 and recovery of β5 subunit activity mitigate multiple myeloma cell susceptibility to proteasome inhibitors.,
International Journal of Hematology, Vol.119, No.3, 303-315, 2024.
(Tokushima University Institutional Repository: 119384,   DOI: 10.1007/s12185-023-03705-9,   PubMed: 38245883)
2. Emiko Nakaue, Jumpei Teramachi, Hirofumi Tenshin, Masahiro Hiasa, Takeshi Harada, Asuka Oda, Yusuke Inoue, Sou Shimizu, Yoshiki Higa, Kimiko Sogabe, Masahiro Oura, Tomoyo Hara, Ryohei Sumitani, Tomoko Maruhashi, Hiroki Yamagami, Itsuro Endo, Eiji Tanaka and Masahiro Abe :
Mechanisms of preferential bone formation in myeloma bone lesions by proteasome inhibitors.,
International Journal of Hematology, 2023.
(Tokushima University Institutional Repository: 118380,   DOI: 10.1007/s12185-023-03601-2,   PubMed: 37039914)
3. Yoshiki Higa, Masahiro Hiasa, Hirofumi Tenshin, Emiko Nakaue, Mariko Tanaka, Sooha Kim, Motosumi Nakagawa, Sou Shimizu, Kotaro Tanimoto, Jumpei Teramachi, Takeshi Harada, Asuka Oda, Masahiro Oura, Kimiko Sogabe, Tomoyo Hara, Ryohei Sumitani, Tomoko Maruhashi, Hiroki Yamagami, Itsuro Endo, Toshio Matsumoto, Eiji Tanaka and Masahiro Abe :
The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf2.,
Antioxidants, Vol.12, No.1, 2023.
(Tokushima University Institutional Repository: 118313,   DOI: 10.3390/antiox12010133,   PubMed: 36670994)
4. Masahiko Watanabe, Nobuhiko Kawai, Manami Shibata, Emiko Nakaue, Shinya Horiuchi and Eiji Tanaka :
Establishment of a new rehabilitation program using masticatory training food for jaw deformity patients.,
Journal of Dental Sciences, Vol.17, No.3, 1217-1224, 2022.
(Tokushima University Institutional Repository: 117259,   DOI: 10.1016/j.jds.2021.12.007,   PubMed: 35784158)

Academic Paper (Unrefereed Paper):

1. Hirofumi Tenshin, Keiichiro Watanabe, Emiko Nakaue, Khurel-Ochir Tsendsuren, Masahiro Hiasa, Shinya Horiuchi and Eiji Tanaka :
Identification of key determinant for predicting feasible mandibular molars distalization,
Journal of Dental Sciences, 2022.
(DOI: 10.1016/j.jds.2022.05.009,   Elsevier: Scopus)

Proceeding of International Conference:

1. Hirofumi Tenshin, Takeshi Harada, Yusuke Inoue, Jumpei Teramachi, Masahiro Hiasa, Sou Shimizu, Emiko Nakaue, Kotaro Tanimoto, Yoshiki Higa, Masahiro Oura, Kimiko Sogabe, Tomoyo Hara, Ryohei Sumitani, Tomoko Maruhashi, Itsuro Endo, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe :
Targeting SLAMF7 to disrupt myeloma-osteoclast interaction: elotuzumabs ADCC activity with Th1-like gamma delta T cells towards osteoclasts and myeloma cells.,
Cancer and bone society young investigator symposium, Feb. 2022.

Proceeding of Domestic Conference:

1. Emiko Nakaue, Jumpei Teramachi, Masahiro Hiasa, Sou Shimizu, Yoshiki Higa, TANAKA Mariko, KIMU Suha, NAKAGAWA Motosumi, Eiji Tanaka and Masahiro Abe :
プロテアソーム阻害薬による骨髄腫骨病変部における骨形成のメカニズム,
第82回日本矯正歯科学会学術大会抄録集, 192, Nov. 2023.
2. Yoshiki Higa, Masahiro Hiasa, NAKAGAWA Motosumi, KIMU Suha, TANAKA Mariko, Emiko Nakaue, Sou Shimizu, Hirofumi Tenshin, Eiji Tanaka and Masahiro Abe :
KEAP1-NRF2軸を介した脂肪細胞分化と骨芽細胞分化の制御機構,
第82回日本矯正歯科学会学術大会抄録集, 194, Nov. 2023.
3. Shinya Horiuchi, Emiko Nakaue, Keiichiro Watanabe, Masahiro Hiasa and Eiji Tanaka :
顎間関係を判断するAIにおける判定根拠に関する検討,
第82回日本矯正歯科学会学術大会抄録集, 208, Nov. 2023.
4. KINJO Soichiro, 塩屋園 玲子, Kaoru Yoshinaga, Emiko Nakaue, Keiichiro Watanabe, Masahiro Hiasa and Eiji Tanaka :
上顎骨前方部延長術を行った口唇口蓋裂患者2症例の術後評価,
The Journal of Chu-Shikoku Orthodontic Society, Vol.35, No.1, 114-115, Aug. 2023.
5. Kim SooHa, Jumpei Teramachi, Masahiro Hiasa, Hirofumi Tenshin, Emiko Nakaue, TANAKA Mariko, NAKAGAWA Motosumi, Itsuro Endo, Takeshi Harada, Eiji Tanaka and Masahiro Abe :
Molecular mechanisms for generation of non-permissive niche for myeloma cells by activated osteoblasts.,
The Annual Meeting of the Japanese Society for Bone and Mineral Research Program & Abstracts, 173, Jul. 2023.
6. Keiichiro Watanabe, Emiko Nakaue, Kumiko Kamada, Natsumi Takamaru, Naito Kurio and Eiji Tanaka :
3DシミュレーションとCAD/CAMスプリントを用いて上下顎移動術を施行した顎偏位を伴う骨格性下顎前突の1例,
The Japanese Journal of Jaw Deformities, Vol.33, No.2, 174, May 2023.
7. Keiichiro Watanabe, Hirofumi Tenshin, Emiko Nakaue, 塩屋園 玲子 and Eiji Tanaka :
上顎歯列の全体的な圧下を行い骨格的な改善を図った，ガミースマイルを伴う成人骨格性上顎前突症例,
第81回日本矯正歯科学会学術大会, Oct. 2022.
8. Yoshiki Higa, Masahiro Hiasa, KIMU Suha, TANAKA Mariko, Emiko Nakaue, Sou Shimizu, Kotaro Tanimoto, Hirofumi Tenshin, Eiji Tanaka and Masahiro Abe :
キサンチンオキシダーゼ阻害薬febuxostatはKEAP1-NRF2軸を介し脂肪細胞分化と骨芽細胞分化を制御する,
第81回日本矯正歯科学会学術大会, Oct. 2022.
9. Sou Shimizu, Jumpei Teramachi, Masahiro Hiasa, Hirofumi Tenshin, Yoshiki Higa, Emiko Nakaue, Masahiro Abe and Eiji Tanaka :
骨髄腫細胞の生存・増殖におけるTAK1-CIP2A経路の重要な役割,
第81回日本矯正歯科学会学術大会, Oct. 2022.
10. Akihiko Iwasa, Yoshiki Higa, Emiko Nakaue, Kaoru Yoshinaga, Sou Shimizu, Yuta Matsuki, Kotaro Tanimoto, Keiichiro Watanabe, Masahiro Hiasa, Shinya Horiuchi and Eiji Tanaka :
特発性下顎頭吸収を呈する矯正患者の下顎頭の形態学的特徴,
第81回日本矯正歯科学会学術大会, Oct. 2022.
11. Emiko Nakaue, Hirofumi Tenshin, Masahiro Hiasa, Jumpei Teramachi, Takeshi Harada, Yusuke Inoue, Kotaro Tanimoto, Sou Shimizu, Yoshiki Higa, Itsuro Endo, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe :
プロテアソーム阻害薬による骨髄腫骨病変部選択的骨形成誘導活性の検討,
第40回日本骨代謝学会学術集会, 141, Jul. 2022.
12. TANAKA Mariko, Masahiro Hiasa, Kotaro Tanimoto, Hirofumi Tenshin, Sou Shimizu, Yoshiki Higa, Emiko Nakaue, KIMU Suha, Jumpei Teramachi, Takeshi Harada, Shingen Nakamura, Itsuro Endo, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe :
不動は骨髄腫骨病変部DPP-4発現増加と骨髄腫の腫瘍進展・髄外播種を加速させる,
第40回日本骨代謝学会学術集会, Jul. 2022.
13. Takeshi Harada, Hirofumi Tenshin, Yusuke Inoue, Ryohei Sumitani, Emiko Nakaue, Jumpei Teramachi, Masahiro Hiasa, Eiji Tanaka, Toshio Matsumoto and Masahiro Abe :
Production of SLAMF7 by osteoclasts and development of novel treatment targeting SLAMF7 against myeloma bone disease,
第40回日本骨代謝学会学術集会, Jul. 2022.
14. Emiko Nakaue, Keiichiro Watanabe, Hirofumi Tenshin, Kaoru Yoshinaga, Yuta Matsuki, Masahiro Hiasa, Shinya Horiuchi and Eiji Tanaka :
Identification of key determinant for predicting feasible mandibular molars distalization,
The Journal of Chu-Shikoku Orthodontic Society, Jul. 2022.
15. Akihiko Iwasa, Yoshiki Higa, Emiko Nakaue, Sou Shimizu, Tatsuya Nakamura, Shinji Fujihara, Shinya Horiuchi and Eiji Tanaka :
上顎埋伏犬歯に対して開窓牽引を行った叢生症例-長期保定観察例-,
The Journal of Chu-Shikoku Orthodontic Society, Jul. 2022.
16. KIMU Suha, Keiichiro Watanabe, Kaoru Yoshinaga, Hirofumi Tenshin, Emiko Nakaue, Yoshiki Higa, 坂本 幸, 近藤 英司, Aki Shimada, Kazuhide Mineda, Soushi Ishida, Aya Miyazaki, Takamasa Kitamura, Masahiro Hiasa, Shinya Horiuchi, Tomonori Iwasaki, Ichiro Hashimoto and Eiji Tanaka :
徳島大学病院における口唇口蓋裂センター設立前後での患者動向の変化 金 秀河(徳島大学 大学院口腔科学教育部口腔顎顔面矯正学分野), 渡邉 佳一郎, 吉永 薫, 天眞 寛文, 中上 絵美子, 比嘉 佳基, 坂本 幸, 近藤 英司, 島田 亜紀, 峯田 一秀, 石田 創士, 宮嵜 彩, 北村 尚正, 日浅 雅博, 堀内 信也, 岩崎 智憲, 橋本 一郎, 田中 栄二 日本口蓋裂学会雑誌(0386-5185)47巻2号 Page135(2022.04),
Journal fo Japanese Cleft Palate Association, Vol.47, No.2, 135, May 2022.
17. Emiko Nakaue, Hirofumi Tenshin, Jumpei Teramachi, Masahiro Hiasa, Takeshi Harada, Kotaro Tanimoto, Sou Shimizu, Yoshiki Higa, Ryohei Sumitani, 丸橋 朋子, Masahiro Oura, Kimiko Sogabe, Shingen Nakamura, Hirokazu Miki, Itsuro Endo, Eiji Tanaka and Masahiro Abe :
The impact of pulsatile proteasome inhibitor on bone metabolism,
International Journal of Myeloma, Vol.12, No.3, 152, May 2022.
18. Keiichiro Watanabe, Hirofumi Tenshin, Kaoru Yoshinaga, Emiko Nakaue, 坂本 幸, Eiji Kondou, Aki Shimada, Kazuhide Mineda, Soushi Ishida, Masahiro Hiasa, Shinya Horiuchi, Tomonori Iwasaki, Ichiro Hashimoto and Eiji Tanaka :
Pre-epiglottic baton plateによる保存的治療で重度気道閉塞の改善がみられたPierre Robin Sequenceの1例,
Journal fo Japanese Cleft Palate Association, Vol.47, No.2, 116, Apr. 2022.
19. Hirofumi Tenshin, Keiichiro Watanabe, Emiko Nakaue and Eiji Tanaka :
歯科矯正用アンカースクリューを用いた積極的な 臼歯圧下により治療を行なった成人骨格性開咬症例,
第80回日本矯正歯科学会学術大会, Oct. 2021.
20. Yuzo Hirai, Keiichiro Watanabe, Emiko Nakaue, Muneyuki Yoshimura, Hirofumi Tenshin, Masahiro Hiasa and Eiji Tanaka :
歯科矯正用アンカースクリューおよび周囲骨の応力分布に及ぼす植立深さの影響:有限要素法による解析,
The Journal of Chu-Shikoku Orthodontic Society, Vol.33, No.1, 80, Jul. 2021.
21. Emiko Nakaue, Shinya Horiuchi, Masahiko Watanabe, Nobuhiko Kawai and Eiji Tanaka :
骨格性下顎前突症患者における口腔周囲機能に関する検討,
The Japanese Journal of Jaw Deformities, Vol.31, No.2, 143, May 2021.
22. Keiichiro Watanabe, Hirofumi Tenshin, Kazuhide Mineda, Soushi Ishida, Kaoru Yoshinaga, Emiko Nakaue, Yoshiki Higa, Aya Miyazaki, Takamasa Kitamura, 坂本 幸, Eiji Kondou, Aki Shimada, Masahiro Hiasa, Shinya Horiuchi, Ichiro Hashimoto and Eiji Tanaka :
当院における口腔内スキャナーを活用した哺乳床早期装着のための取り組み,
Journal fo Japanese Cleft Palate Association, Vol.46, No.2, 123, Apr. 2021.
23. Shinya Horiuchi, Saki Saitoh, Emiko Nakaue, Masahiko Watanabe, Nobuhiko Kawai and Eiji Tanaka :
AIにて考察する最大口唇圧と顔面形態との関連性について,
Orthodontic Waves, Oct. 2020.
24. Hirofumi Tenshin, Hiroko Sato, Akihiko Iwasa, Emiko Nakaue, Masaki Sawada, Daishi Arai, Shinya Horiuchi and Eiji Tanaka :
哺乳様式と不正咬合との関連性についての検討．,
第63回中・四国矯正歯科学会大会, Jul. 2020.
25. Emiko Nakaue, Keiichiro Watanabe, Hiroki Mori, Hirofumi Tenshin, Shinya Horiuchi and Eiji Tanaka :
カモフラージュ治療が行われた片側性完全唇顎口蓋裂患者の動的治療終了時の顎顔面形態の特徴,
第30回日本顎変形症学会総会・学術大会, Vol.30, No.2, 164, Jun. 2020.
26. Emiko Nakaue, Keiichiro Watanabe, Hiroki Mori, Hirofumi Tenshin, Shinya Horiuchi and Eiji Tanaka :
カモフラージュ治療が行われた片側性完全唇顎口蓋裂患者の動的治療終了時の顎顔面形態の特徴,
第44回日本口蓋裂学会総会・学術集会, Jun. 2020.