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Tokushima University ⟩ University Hospital ⟩ 先端医科医療開発研究プロジェクト ⟩
Tokushima University ⟩ University Hospital ⟩ Clinical Division ⟩ Department of Internal Medicine ⟩ Respiratory and Rheumatology Medicine ⟩
Tokushima University ⟩ Faculty of Medicine ⟩ School of Medicine ⟩ Course of Bioregulation and Medical Oncology ⟩ Respiratory Medicine and Rheumatology ⟩ 		(Files for researchmap) [PDF manual] [Auto-propagate to researchmap]

Research

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Academic Paper (Judged Full Paper):

1. Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Kojin Murakami, Takeshi Imakura, Yuya Yamashita, Kozo Kagawa, Hiroshi Kawano, Eiji Hara and Yasuhiko Nishioka :
A novel BRD4 degrader, ARV-825, attenuates lung fibrosis through senolysis and antifibrotic effect.,
Respiratory Investigation, Vol.61, No.6, 781-792, 2023.
(DOI: 10.1016/j.resinv.2023.08.003,   PubMed: 37741093)
2. Takeshi Imakura, Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Takahiro Niimura, Kojin Murakami, Yuya Yamashita, Keiko Haji, Nobuhito Naito, Kozo Kagawa, Hiroshi Kawano, Yoshito Zamami, Keisuke Ishizawa and Yasuhiko Nishioka :
A polo-like kinase inhibitor identified by computational repositioning attenuates pulmonary fibrosis.,
Respiratory Research, Vol.24, No.1, 148, 2023.
(Tokushima University Institutional Repository: 119057,   DOI: 10.1186/s12931-023-02446-x,   PubMed: 37269004)
3. Atsushi Mitsuhashi, Kazuya Koyama, Hirokazu Ogino, Tania Afroj, Thi Na Nguyen, Hiroto Yoneda, Kenji Otsuka, Masamichi Sugimoto, Osamu Kondoh, Hiroshi Nokihara, Masaki Hanibuchi, Hiromitsu Takizawa, Tsutomu Shinohara and Yasuhiko Nishioka :
Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade.,
Cell Reports, Vol.42, No.3, 112162, 2023.
(Tokushima University Institutional Repository: 118888,   DOI: 10.1016/j.celrep.2023.112162,   PubMed: 36870329)
4. Kozo Kagawa, Seidai Satou, Kazuya Koyama, Takeshi Imakura, Kojin Murakami, Yuya Yamashita, Nobuhito Naito, Hirohisa Ogawa, Hiroshi Kawano and Yasuhiko Nishioka :
The lymphocyte-specific protein tyrosine kinase-specific inhibitor A-770041 attenuates lung fibrosis via the suppression of TGF-β production in regulatory T-cells.,
PLoS ONE, Vol.17, No.10, e0275987, 2022.
(Tokushima University Institutional Repository: 118786,   DOI: 10.1371/journal.pone.0275987,   PubMed: 36301948)
5. Tamotsu Tanaka, Kazuya Koyama, Naoko Takahashi, Katsuya Morito, Hanif Ali, Momoyo Azuma, Kozo Kagawa, Hiroshi Kawano, Rumana Yesmin, Mutsumi Aihara and Yasuhiko Nishioka :
Lysophosphatidic acid, ceramide 1-phosphate and sphingosine 1-phosphate in peripheral blood of patients with idiophathic pulmonary fibrosis,
The Journal of Medical Investigation : JMI, Vol.69, No.3.4, 196-203, 2022.
(Tokushima University Institutional Repository: 117621,   DOI: 10.2152/jmi.69.196,   PubMed: 36244770)
6. Atsushi Mitsuhashi, Kensuke Kondoh, Kazuki Horikawa, Kazuya Koyama, Thi Na Nguyen, Tania Afroj, Hiroto Yoneda, Kenji Otsuka, Hirokazu Ogino, Hiroshi Nokihara, Tsutomu Shinohara and Yasuhiko Nishioka :
Programmed death (PD)-1/PD-ligand 1 blockade mediates antiangiogenic effects by tumor-derived CXCL10/11 as a potential predictive biomarker.,
Cancer Science, Vol.112, No.12, 4853-4866, 2021.
(Tokushima University Institutional Repository: 117305,   DOI: 10.1111/cas.15161,   PubMed: 34628702)
7. Takeshi Imakura, Seidai Satou, Tetsu Tomonari, Kojin Murakami, Naoki Takahashi, Nobuhito Naito, Masato Mima, Kozo Kagawa, Kazuya Koyama, Haruka Nishimura, Hiroshi Kawano, Hiroshi Nokihara, Masahiko Azuma, Tetsuji Takayama and Yasuhiko Nishioka :
Lenvatinib-induced Interstitial Pneumonia in a Patient with Hepatocellular Carcinoma.,
Internal Medicine, Vol.61, No.8, 1211-1217, 2021.
(Tokushima University Institutional Repository: 118011,   DOI: 10.2169/internalmedicine.7300-21,   PubMed: 34544944)
8. Takuma Isshiki, Sakae Homma, Yoshinobu Eishi, Matsuko Yabe, Kazuya Koyama, Yasuhiko Nishioka, Tetsuo Yamaguchi, Keisuke Uchida, Kurara Yamamoto, Kenichi Ohashi, Atsushi Arakawa, Kazutoshi Shibuya, Susumu Sakamoto and Kazuma Kishi :
Usefulness of imunohistochemical detection of Propionibacterium acnes in granulomas for differentiating sarcoidosis from other garanulomatous diseases; comparison between manual and automated immunohistochemical detection methods.,
Microorganisms, Vol.9, No.8, 2021.
(Tokushima University Institutional Repository: 117354,   DOI: 10.3390/microorganisms9081668,   PubMed: 34442747)
9. Tania Afroj, Atsushi Mitsuhashi, Hirokazu Ogino, Atsuro Saijo, Kenji Otsuka, Hiroto Yoneda, Makoto Tobiume, Thi Na Nguyen, Hisatsugu Goto, Kazuya Koyama, Masamichi Sugimoto, Osamu Kondoh, Hiroshi Nokihara and Yasuhiko Nishioka :
Blockade of PD-1/PD-L1 Pathway Enhances the Antigen-Presenting Capacity of Fibrocytes.,
The Journal of Immunology, Vol.206, No.6, 1204-1214, 2021.
(Tokushima University Institutional Repository: 115981,   DOI: 10.4049/jimmunol.2000909,   PubMed: 33504617)
10. Hiroshi Kawano, Kazuya Koyama, Haruka Nishimura, Yuko Toyoda, Kozo Kagawa, Seidai Satou, Nobuhito Naito, Hisatsugu Goto, Yutaka Inagaki and Yasuhiko Nishioka :
Development of improved method to identify and analyze lung fibrocytes with flow cytometry in a reporter mouse strain.,
Immunity, Inflammation and Disease, Vol.9, No.1, 120-127, 2020.
(Tokushima University Institutional Repository: 116531,   DOI: 10.1002/iid3.361,   PubMed: 33369271)
11. Shun Morizumi, Seidai Satou, Kazuya Koyama, Hiroyasu Okazaki, Yajuan Chen, Hisatsugu Goto, Kozo Kagawa, Hirohisa Ogawa, Haruka Nishimura, Hiroshi Kawano, Yuko Toyoda, Hisanori Uehara and Yasuhiko Nishioka :
Blockade of Pan-Fibroblast Growth Factor Receptors Mediates Bidirectional Effects in Lung Fibrosis.,
American Journal of Respiratory Cell and Molecular Biology, Vol.63, No.3, 317-326, 2020.
(Tokushima University Institutional Repository: 115073,   DOI: 10.1165/rcmb.2019-0090OC,   PubMed: 32338990)
12. Mayo Kondou, Toshifumi Tezuka, Hirohisa Ogawa, Kazuya Koyama, Hiroki Bando, Masahiko Azuma and Yasuhiko Nishioka :
Lysophosphatidic Acid Regulates the Differentiation of Th2 Cells and Its Antagonist Suppresses Allergic Airway Inflammation.,
International Archives of Allergy and Immunology, Vol.182, No.1, 1-13, 2020.
(Tokushima University Institutional Repository: 115394,   DOI: 10.1159/000509804,   PubMed: 32846422)
13. Kenji Otsuka, Atsushi Mitsuhashi, Hisatsugu Goto, Masaki Hanibuchi, Kazuya Koyama, Hirohisa Ogawa, Hirokazu Ogino, Atsuro Saijo, Hiroyuki Kozai, Hiroto Yoneda, Makoto Tobiume, Masatoshi Kishuku, Keisuke Ishizawa and Yasuhiko Nishioka :
Anti-PD-1 antibody combined with chemotherapy suppresses the growth of mesothelioma by reducing myeloid-derived suppressor cells.,
Lung Cancer, Vol.146, 86-96, 2020.
(Tokushima University Institutional Repository: 115324,   DOI: 10.1016/j.lungcan.2020.05.023,   PubMed: 32526602)
14. Takeshi Imakura, Yuko Toyoda, Seidai Satou, Kazuya Koyama, Haruka Nishimura, Kozo Kagawa, Naoki Takahashi, Nobuhito Naito, Kojin Murakami, Hiroshi Kawano, Masahiko Azuma, Tsutomu Shinohara and Yasuhiko Nishioka :
Distinct improvement of pulmonary function, ground-glass opacity, hypoxia and physical findings in an idiopathic pulmonary fibrosis patient after pirfenidone treatment : a case report with a review of the literature.,
The Journal of Medical Investigation : JMI, Vol.67, No.3.4, 358-361, 2020.
(Tokushima University Institutional Repository: 115454,   DOI: 10.2152/jmi.67.358,   PubMed: 33148916)

Review, Commentary:

1. Yasuhiko Nishioka, Kojin Murakami, Kazuya Koyama and Seidai Satou :
肺線維化機序,
Nihon Rinsho. Japanese Journal of Clinical Medicine, Vol.80, No.9, 1351-1355, Sep. 2022.
2. Kazuya Koyama and Yasuhiko Nishioka :
肺の線維化 : 肺線維症と抗線維化薬 (特集 組織の線維化),
Clinical Immunology & Allergology, Vol.76, No.2, 139-146, Aug. 2021.
(CiNii: 1521136281215665152)

Proceeding of International Conference:

1. Atsushi Mitsuhashi, Kazuya Koyama, Afroj Tania, Atsuro Saijo, Makoto Tobiume, Hirokazu Ogino, Sugimoto Masamichi, Kondoh Osamu, Hiroshi Nokihara and Yasuhiko Nishioka :
The identification and analysis of fibrocyte regulating the tumor immune microenvironment,
The 9th Joint Meeting 2023 (Tokushima Univ., Gifu Univ., SNU, and IBS-KAIST)., Daejeon, Oct. 2023.
2. Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Murakami Kojin, Yuya Yamashita, Danzan NandinErdene, Bando Hiroki, Keiko Haji, Nobuhito Naito, Hiroshi Kawano, Eiji Hara and Yasuhiko Nishioka :
A novel senolytic drug, ARV-825, ameliorates experimental lung fibrosis,
ERS International Congress 2023, Milano, Sep. 2023.
3. Hiroki Bando, Seidai Satou, Hirohisa Ogawa, Kazuya Koyama, Murakami Kojin, Yuya Yamashita, Danzan Nandin-Erdene, Keiko Haji, Nobuhito Naito, Hiroshi Kawano and Yasuhiko Nishioka :
Anamorelin, a ghrelin receptor agonist, inhibited the allergic airway inflammation in mice,
ERS International Congress 2023, Milano, Sep. 2023.
4. Murakami Kojin, Nishimura Haruka, Hiroshi Kawano, Danzan Nandin-Erdene, Yuya Yamashita, Keiko Haji, Nobuhito Naito, Kazuya Koyama, Seidai Satou and Yasuhiko Nishioka :
Analysis of the Anti-fibrotic Potential of JAK Inhibitors in a Bleomycin-induced Pulmonary Fibrosis Model,
ATS 2023, Washington, DC, May 2023.
5. Kazuya Koyama, Seidai Satou, Hiroshi Kawano, Hiroshi Kawano, Atsushi Mitsuhashi, Murakami Kojin, Yuya Yamashita, Keiko Haji, Kozo Kagawa, Hirohisa Ogawa and Yasuhiko Nishioka :
Evaluation of fibrocytes in silica-induced and bleomycin-induced pulmonary fibrosis model in mice by single cell RNA-seq analysis,
APSR 2022, Seoul, Nov. 2022.
6. Imakura Takeshi, Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Takahiro Niimura, Murakami Kojin, Yuya Yamashita, Keiko Haji, Nobuhito Naito, Kozo Kagawa, Hiroshi Kawano, Yoshito Zamami, Keisuke Ishizawa and Yasuhiko Nishioka :
Computational drug repositioning and wet-lab validation approach identifies polo-like kinase inhibitors as potential therapeutics for pulmonary fibrosis,
ERS International Congress 2022, Barcelona, Sep. 2022.
7. Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Kojin Murakami, Takeshi Imakura, Yuya Yamashita, Keiko Haji, Kozo Kagawa, Hiroshi Kawano, Eiji Hara and Yasuhiko Nishioka :
A Novel Senolytic Agent, ARV-825, Ameliorates Bleomycin-InducedPulmonary Fibrosis in Mice,
ATS 2022 International Conference, San Francisco, May 2022.
8. Takeshi Imakura, Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Takahiro Niimura, Kojin Murakami, Yuya Yamashita, Keiko Haji, Nobuhito Naito, Kozo Kagawa, Hiroshi Kawano, Yoshito Zamami, Keisuke Ishizawa and Yasuhiko Nishioka :
Computational Drug Repositioning Approach Identifies Polo-Like KinaseInhibitors as Potential Therapeutics for Pulmonary Fibrosis,
ATS 2022 International Conference, San Francisco, May 2022.
9. Kazuya Koyama, Hiroshi Kawano, Atsushi Mitsuhashi, Kojin Murakami, Takeshi Imakura, Yuya Yamashita, Keiko Haji, Kozo Kagawa, Seidai Satou, Hirohisa Ogawa and Yasuhiko Nishioka :
Single Cell RNA-seq Analysis of Fibrocytes in Silica Induced Mouse Pulmonary Fibrosis Model,
ATS 2022 International Conference, San Francisco, May 2022.
10. Imakura Takeshi, Seidai Satou, Kazuya Koyama, Takahiro Niimura, Kohjin Murakami, Yuya Yamashita, Takahashi Naoki, Nobuhito Naito, Kozo Kagawa, Hiroshi Kawano, Yoshito Zamami, Keisuke Ishizawa and Yasuhiko Nishioka :
Polo-like kinase inhibitors identified by computational repositioning attenuates bleomycin-induced pulmonary fibrosis in mice,
APSR 2021, Kyoto and online, Nov. 2021.
11. Kohjin Murakami, Takahashi Naoki, Seidai Satou, Imakura Takeshi, Yuya Yamashita, Kozo Kagawa, Kazuya Koyama, Hiroshi Kawano, Tanigawara Kazuaki, Toriumi Wataru and Yasuhiko Nishioka :
Therapeutic effect of oligonucleotide therapeutics PK-7010 in mouse model of bleomycin-induced lung fibrosis,
APSR 2021, Kyoto and online, Nov. 2021.
12. Nobuhito Naito, Hiroshi Kawano, Imakura Takeshi, Yuya Yamashita, Kohjin Murakami, Kozo Kagawa, Kazuya Koyama, Seidai Satou, Hiroshi Nokihara, Inagaki Yutaka and Yasuhiko Nishioka :
Development of improved method to identify and analyze lung fibrocytes with flow cytometry in a reporter mouse strain,
APSR 2021, Kyoto and online, Nov. 2021.
13. Kozo Kagawa, Kazuya Koyama, Seidai Satou, Imakura Takeshi, Kohjin Murakami, Yuya Yamashita, Takahashi Naoki, Nobuhito Naito, Hiroshi Kawano and Yasuhiko Nishioka :
A Lck-specific inhibitor, A-770041, attenuates pulmonary fibrosis via the suppression of TGF-b production in regulatory T cells,
APSR 2021, Kyoto and online, Nov. 2021.
(DOI: 10.1111/resp.14150_945)
14. Hiroshi Kawano, Nishimura Haruka, Imakura Takeshi, Yuya Yamashita, Kohjin Murakami, Nobuhito Naito, Kozo Kagawa, Kazuya Koyama, Seidai Satou, Hiroshi Nokihara and Yasuhiko Nishioka :
Analysis of anti-fibrotic potential of JAK inhibitors in bleomycin-induced pulmonary fibrosis model,
APSR 2021, Kyoto and online, Nov. 2021.
(DOI: 10.1111/resp.14150_915)
15. Kozo Kagawa, Kazuya Koyama, Seidai Satou, Imakura Takeshi, Kohjin Murakami, Takahashi Naoki, Nobuhito Naito, Nishimura Haruka, Hiroshi Kawano and Yasuhiko Nishioka :
Anti-fibrotic efficacy of Lck inhibitor via the suppression of TGF-β production in regulatory T cells,
ERS International Congress 2021, WEB, Sep. 2021.
(DOI: 10.1183/13993003.congress-2021.PA3285)
16. Takahashi Naoki, Seidai Satou, Imakura Takeshi, Kohjin Murakami, Nobuhito Naito, Kozo Kagawa, Kazuya Koyama, Hiroshi Kawano, Tanigawara Kazuaki, Toriumi Wataru and Yasuhiko Nishioka :
Oligonucleotide therapeutics PK-7010 in combination with nintedanib ameliorates bleomycin-induced pulmonary fibrosis in mice,
ATS 2021, 米国(WEB), May 2021.
(DOI: 10.1164/ajrccm-conference.2021.203.1_MeetingAbstracts.A4444)
17. Kazuya Koyama, Hiroshi Kawano, Yuya Yamashita, Imakura Takeshi, Takahashi Naoki, Nobuhito Naito, Seidai Satou and Yasuhiko Nishioka :
Clinical Features of the Acute Exacerbation of Rheumatoid Arthritis-Associated Interstitial Lung Disease,
ATS 2021, 米国(WEB), May 2021.
18. Isshiki Takuma, Homma Sakae, Yabe Matsuko, Kazuya Koyama, Yasuhiko Nishioka, Yamaguchi Tetsuo, Uchida Keisuke, Eishi Yoshinobu, Shibuya Kazutoshi, Sakamoto Susumu and Kishi Kazuma :
Usefulness of Immunohistochemical detection of Propionibacterium acnes in granulomas for the differentiation of sarcoidosis and other granulomatous diseases,
ATS 2021, 米国(WEB), May 2021.
19. Takahashi Naoki, Seidai Satou, Imakura Takeshi, Murakami Kojin, Nobuhito Naito, Kozo Kagawa, Kazuya Koyama, Hiroshi Kawano, Tanigawara Kazuaki, Toriumi Wataru and Yasuhiko Nishioka :
The novel oligonucleotide therapeutics PK-7010 for TGF-β1 ameliorates bleomycin-induced pulmonary fibrosis in micen,
ERS International Congress 2020 Virtual, WEB, Sep. 2020.
(DOI: 10.1183/13993003.congress-2020.3373)
20. Atsushi Mitsuhashi, Afroj Tania, Atsuro Saijo, Kenji Otsuka, Hiroto Yoneda, Kazuya Koyama, Sugimoto Masamichi, Kondoh Osamu, Hiroshi Nokihara and Yasuhiko Nishioka :
The role of fibrocyte-like cells in combination treatment of immune checkpoint inhibitor with antiangiogenic agents,
ERS International Congress 2020 Virtual, WEB, Sep. 2020.
(DOI: 10.1183/13993003.congress-2020.1134)
21. Seidai Satou, Yamamoto Takushi, Waki Kana, Morimoto Yuki, Imakura Takeshi, Murakami Kojin, Takahashi Naoki, Nobuhito Naito, Kozo Kagawa, Kazuya Koyama, Hiroshi Kawano, Koichi Tsuneyama and Yasuhiko Nishioka :
Analysis of localization of nintedanib and cyclophosphamide in pulmonary fibrosisusing the iMScope TRIOS,
ERS International Congress 2020 Virtual, WEB, Sep. 2020.
(DOI: 10.1183/13993003.congress-2020.3385)
22. Kazuya Koyama, Sakamoto Susumu, Homma Sakae, Seidai Satou, Masaki Hanibuchi, Masuda Kiyoshi, Imoto Isei, Yuko Toyoda, Isshiki Takuma, Miyoshi Shion, Kato Motoyasu, Takahashi Kazuhisa, Kataoka Kensuke, Kondoh Yasuhiro and Yasuhiko Nishioka :
The Relationship Between Single-Nucleotide Polymorphisms Within Tollip and the Efficacy of Inhaled N-Acetylcysteine Therapy in Idiopathic Pulmonary Fibrosis,
ATS 2020 VIRTUAL, WEB, Aug. 2020.
(DOI: 10.1164/ajrccm-conference.2020.201.1_MeetingAbstracts.A1494)

Proceeding of Domestic Conference:

1. Hiroki Bandoh, Seidai Satou, Kojin Murakami, Yuya Yamashita, Nobuhito Naitoh, Kazuya Koyama, Hiroshi Kawano, Hirohisa Ogawa and Yasuhiko Nishioka :
グレリン受容体作動薬アナモレリンのアレルギー性気道炎症モデルマウスにおける検討,
第72回日本アレルギー学会学術大会, Oct. 2023.
2. Keiko Haji, Seidai Satou, Hirohisa Ogawa, Kojin Murakami, Yuya Yamashita, Kazuya Koyama, Hiroshi Kawano, 小林 克利, 諸星 俊郎 and Yasuhiko Nishioka :
オートタキシン阻害作用を有する 2ccPA の肺線維症における有効性の検討,
第3回日本びまん性肺疾患研究会, Sep. 2023.
3. Atsushi Mitsuhashi, Kazuya Koyama, Hirokazu Ogino, 杉本 正道, 根東 攝, Hiroshi Nokihara and Yasuhiko Nishioka :
腫瘍内 fibrocyte 遊走・分化制御がもたらす腫瘍免疫微小環境への影響,
第82回日本癌学会学術総会, Sep. 2023.
4. Atsushi Mitsuhashi, Kazuya Koyama, アフローズ タニア, Atsuro Saijo, Makoto Tobiume, Hirokazu Ogino, 杉本 正道, 根東 攝, Hiroshi Nokihara and Yasuhiko Nishioka :
腫瘍内 fibrocyte の同定と制御による新規がん治療開発への橋渡し研究,
第82回日本癌学会学術総会, Sep. 2023.
5. 山本 浩生, Hiroki Bandoh, Keiko Haji, Michihiro Kunishige, 梶本 達也, Kazuya Koyama, Kozo Kagawa, Seidai Satou, Masaki Hanibuchi and Yasuhiko Nishioka :
自然経過で嚢胞性画像変化および呼吸機能の改善を認めた重症COVID-19の1例,
第68回日本呼吸器学会中国・四国地方会, Jul. 2023.
6. Hiroki Bandoh, Seidai Satou, Kojin Murakami, Yuya Yamashita, Nobuhito Naito, Kazuya Koyama, Hiroshi Kawano, Hirohisa Ogawa and Yasuhiko Nishioka :
グレリン受容体作動薬アナモレリンのアレルギー性気道炎症モデルマウスにおける検討,
第63回日本呼吸器学会学術講演会, Apr. 2023.
7. Kojin Murakami, Seidai Satou, Yuya Yamashita, Keiko Haji, 坂東 弘基, Nobuhito Naito, Kazuya Koyama, Hiroshi Kawano, 稲村 典昭, 蓮見 惠司 and Yasuhiko Nishioka :
新規可溶性エポキシヒドロラーゼ阻害薬SMTP-44Dの肺線維症に対する有効性の検討,
第63回日本呼吸器学会学術講演会, Apr. 2023.
8. Nobuhito Naito, 西村 春佳, Yuya Yamashita, Kojin Murakami, Keiko Haji, Kazuya Koyama, Hirokazu Ogino, Seidai Satou, Hiroshi Kawano, Masaki Hanibuchi and Yasuhiko Nishioka :
ブレオマイシン誘発肺線維症モデルマウスを用いたJAK阻害薬の抗線維化効果についての検討,
第50回日本臨床免疫学会総会, Oct. 2022.
9. 小倉 佑一朗, Keiko Haji, 近藤 健介, Kenji Otsuka, Hirokazu Ogino, Kazuya Koyama, 村上 行人, Hiroki Bandoh, Seidai Satou, Masaki Hanibuchi and Yasuhiko Nishioka :
間質性肺炎への治療反応性から肝肺症候群の併存が顕在化した一例,
第66回日本呼吸器学会中国・四国地方会, Jul. 2022.
10. Kojin Murakami, 原田 紗希, Takeshi Imakura, Atsushi Mitsuhashi, 小川 瑛, TSUKAZAKI Yuki, Ryohiko Ozaki, YABUKI Yohhei, Kozo Kagawa, Hiroto Yoneda, Akane Abe, Hirokazu Ogino, Kazuya Koyama, Seidai Satou, Satoshi Sakaguchi and Yasuhiko Nishioka :
抗GM-CSF抗体測定が早期診断に有用であった自己免疫性肺胞蛋白症の一例,
第45回日本呼吸器内視鏡学会学術集会, May 2022.
11. Seidai Satou, Kazuya Koyama, Hirohisa Ogawa, Kojin Murakami, Takeshi Imakura, Yuya Yamashita, Hiroshi Kawano, Eiji Hara and Yasuhiko Nishioka :
Antifibrotic and senolytic activity of novel BRD4 degrader ARV825 in experimental model of lung fibrosis,
The 62nd Annual Meeting of the Japanese Respiratory Society, Apr. 2022.
12. Kazuya Koyama, Atsushi Mitsuhashi, Takeshi Imakura, Kojin Murakami, Kozo Kagawa, Seidai Satou, Hiroshi Kawano, Hirohisa Ogawa and Yasuhiko Nishioka :
シングルセル解析を用いた肺線維症マウスモデルにおけるfibrocyteの検討,
第62回日本呼吸器学会学術講演会, Apr. 2022.
13. Hiroshi Kawano, Takeshi Imakura, Kojin Murakami, Nobuhito Naito, Kozo Kagawa, Kazuya Koyama, Seidai Satou, Hiroshi Nokihara and Yasuhiko Nishioka :
レポーターマウスを用いた肺線維細胞の新規同定法,
第62回日本呼吸器学会学術講演会, Apr. 2022.
14. Takeshi Imakura, Seidai Satou, Kazuya Koyama, Takahiro Niimura, Kojin Murakami, Yuya Yamashita, Keiko Haji, Kozo Kagawa, Hiroshi Kawano, Yoshito Zamami, Keisuke Ishizawa and Yasuhiko Nishioka :
In silico解析により同定されたPLK阻害剤のブレオマイシン誘発肺線維症モデルマウスにおける効果の検討,
第62回日本呼吸器学会学術講演会, Apr. 2022.
15. 高丸 利加子, YABUKI Yohhei, 磯村 祐太, Kozo Kagawa, Kazuya Koyama, Kenji Otsuka, Hirokazu Ogino, Seidai Satou, Hiroshi Kawano, Hiroshi Nokihara and Yasuhiko Nishioka :
自然退縮を認めた気管支原発唾液腺型腫瘍の1例,
第30回日本呼吸器内視鏡学会中国四国支部会, Dec. 2021.
16. 小川 瑛, YABUKI Yohhei, 青井 優, Kozo Kagawa, Kazuya Koyama, Hirokazu Ogino, Seidai Satou, Hiroshi Kawano, Hiroshi Nokihara and Yasuhiko Nishioka :
両側肺に多発する斑状影を呈した自己免疫性肺胞蛋白症の1例,
第65回日本呼吸器学会中国・四国地方会, Dec. 2021.
17. Kazuya Koyama, Hiroshi Kawano and Yasuhiko Nishioka :
肺線維化におけるシングルセル解析,
第1回日本びまん性肺疾患研究会(基礎研究特別講演), Oct. 2021.
18. Takeshi Imakura, Seidai Satou, Kazuya Koyama, Takahiro Niimura, Kohjin Murakami, Naoki Takahashi, Kozo Kagawa, Yoshito Zamami, Keisuke Ishizawa and Yasuhiko Nishioka :
In silico 解析を用いた肺線維症に対する新規治療薬の探索,
第1回日本びまん性肺疾患研究会, Oct. 2021.
19. Kohjin Murakami, Naoki Takahashi, Seidai Satou, Takeshi Imakura, Yuya Yamashita, Kozo Kagawa, Kazuya Koyama, Hiroshi Kawano, 谷川原 万顕, 鳥海 亙 and Yasuhiko Nishioka :
ブレオマイシン誘発肺線維症モデルマウスにおける新規核酸医薬の有効性の検討,
第1回日本びまん性肺疾患研究会, Oct. 2021.
20. Satoshi Sakaguchi, YABUKI Yohhei, Takeshi Imakura, Hiroto Yoneda, Kohjin Murakami, Kazuya Koyama, Kozo Kagawa, 小川 瑛, Hirokazu Ogino, Seidai Satou, Hiroshi Kawano, Hiroshi Nokihara and Yasuhiko Nishioka :
索状の小葉間隔壁の肥厚を認め胸腔鏡下肺生検にて診断した間質性肺炎の1例,
第63回日本呼吸器学会中国・四国地方会, Aug. 2021.
21. Kazuya Koyama, Masaki Hanibuchi, Yuko Toyoda, 一色 琢磨, 三好 嗣臣, 坂本 晋, 加藤 元康, 髙橋 和久, 片岡 健介, 近藤 康博, Yasuhiko Nishioka and 本間 栄 :
特発性肺線維症におけるTOLLIP遺伝子多型とN-アセチルシステイン吸入療法の有効性の検討,
第61回日本呼吸器学会学術講演会, Apr. 2021.
22. Kohjin Murakami, Seidai Satou, Takeshi Imakura, 西村 春佳, Naoki Takahashi, Nobuhito Naito, Kozo Kagawa, Kazuya Koyama, Hiroshi Kawano, Masahiko Azuma, Hiroshi Nokihara and Yasuhiko Nishioka :
抗線維化薬2剤を切り替えて使用した特発性肺線維症症例の後方視的検討,
第61回日本呼吸器学会学術講演会, Apr. 2021.
23. 西村 春佳, Seidai Satou, Takeshi Imakura, Kohjin Murakami, Nobuhito Naito, Kozo Kagawa, Kazuya Koyama, Hiroshi Kawano, Hiroshi Nokihara and Yasuhiko Nishioka :
ブレオマイシン誘発肺線維症モデルマウスにおけるJAK阻害剤の効果に関する検討,
第61回日本呼吸器学会学術講演会, Apr. 2021.
24. Naoki Takahashi, Seidai Satou, Takeshi Imakura, Kohjin Murakami, Nobuhito Naito, Kozo Kagawa, Kazuya Koyama, Hiroshi Kawano, Hiroshi Nokihara, 谷川原 万顕, 鳥海 亙 and Yasuhiko Nishioka :
ブレオマイシン誘発肺線維症モデルマウスにおける核酸医薬PK-7010とnintedanibの併用効果の検討,
第61回日本呼吸器学会学術講演会, Apr. 2021.
25. 一色 琢磨, 本間 栄, 矢部 マツ子, Kazuya Koyama, Yasuhiko Nishioka, 山口 哲生, 内田 圭介, 江石 義信, 渋谷 和俊, 坂本 晋 and 岸 一馬 :
サルコイドーシス診断におけるPAB抗体免疫染色の有用性の検討,
第61回日本呼吸器学会学術講演会, Apr. 2021.
26. 磯村 祐太, Nobuhito Naito, 山下 雄也, Asami Fukuya, Kazuya Koyama, Seidai Satou, Hiroshi Kawano, Hiroshi Nokihara and Yasuhiko Nishioka :
当科における胸水貯留を呈した膠原病および類縁疾患症例の検討,
第64回日本呼吸器学会中国・四国地方会, Nov. 2020.
27. Yuko Toyoda, Seidai Satou, Kazuya Koyama, Kozo Kagawa, 上甲 剛, 江頭 玲子, 寺崎 泰弘, 蛇澤 晶, 萩原 弘一, 稲瀬 直彦 and Yasuhiko Nishioka :
特発性肺骨化症全国調査(中間報告),
第60回日本呼吸器学会学術講演会, Sep. 2020.
28. 髙橋 直希, Seidai Satou, Kazuya Koyama, Kozo Kagawa, Nobuhito Naito, 今倉 健, Yuko Toyoda, Hiroshi Kawano, 谷川原 万顕, 鳥海 亙 and Yasuhiko Nishioka :
ブレオマイシン誘発肺線維症モデルマウスにおける核酸医薬PK-7010の抗線維化効果の検討,
第60回日本呼吸器学会学術講演会, Sep. 2020.
29. Kozo Kagawa, Kazuya Koyama, Seidai Satou, Naoki Takahashi, 西村 春佳, Hiroshi Kawano, Yuko Toyoda, Tsutomu Shinohara and Yasuhiko Nishioka :
ブレオマイシン肺線維症マウスモデルにおけるLck阻害の抗線維化効果,
第60回日本呼吸器学会学術講演会, Sep. 2020.
30. Yasuhiko Nishioka, Kazuya Koyama, Atsushi Mitsuhashi, Afroj Tania and Hiroshi Kawano :
肺線維症モデルにおけるscRNA-Seqを用いた線維細胞の解析,
第60回日本呼吸器学会学術講演会(シンポジウム), Sep. 2020.
31. Seidai Satou, Kohjin Murakami, Yuko Toyoda, Kazuya Koyama, 西村 春佳, Kozo Kagawa, 髙橋 直希, Hiroshi Kawano, Masahiko Azuma and Yasuhiko Nishioka :
2剤の抗線維化薬を使用した特発性肺線維症症例の検討,
第117回日本内科学会講演会, Aug. 2020.

Grants-in-Aid for Scientific Research (KAKEN Grants Database @ NII.ac.jp)

  • 肺がん・中皮腫における新たな抗原提示細胞の同定から革新的複合がん免疫療法への展開 (Project/Area Number: 23K24340 )
  • 多種肺線維症マウスモデル間のシングルセル解析データ比較による炎症細胞機能の解析 (Project/Area Number: 22K16195 )
  • Functional Analysis of TAS-115, a Second Generation Antifibrotic Tyrosine Kinase Inhibitor, and its Clinical Application (Project/Area Number: 20K17183 )
  • Search by Researcher Number (90724089)